Gene Symbol | TOP2 |
Entrez Gene ID | 855636 |
Full Name | DNA topoisomerase 2 |
Synonyms | TOR3,TRF3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » TOP2 cDNA ORF clone
Gene Symbol | TOP2 |
Entrez Gene ID | 855636 |
Full Name | DNA topoisomerase 2 |
Synonyms | TOR3,TRF3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182926.3 | NP_014311.3 | DNA topoisomerase 2 |
Saccharomyces cerevisiae (baker's yeast) | TOP2 | NP_014311.3 |
Schizosaccharomyces pombe (fission yeast) | top2 | NP_595805.1 |
Oryza sativa (rice) | Os02g0699700 | NP_001047833.1 |
Pan troglodytes (chimpanzee) | TOP2B | XP_516332.3 |
TOP2B | XP_001092092.2 | |
Gallus gallus (chicken) | TOP2B | NP_990413.1 |
Neurospora crassa | NCU06338 | XP_962372.2 |
Danio rerio (zebrafish) | top2b | NP_001038656.1 |
Bos taurus (cattle) | TOP2B | XP_002698796.2 |
Mus musculus (house mouse) | Top2b | NP_033435.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_06162 | XP_003712042.1 |
Arabidopsis thaliana (thale cress) | TOPII | NP_001118686.1 |
Homo sapiens (human) | TOP2B | NP_001059.2 |
Canis lupus familiaris (dog) | TOP2B | XP_534241.3 |
Rattus norvegicus (Norway rat) | Top2b | NP_001094328.1 |
Kluyveromyces lactis | KLLA0C13838g | XP_452818.1 |
Eremothecium gossypii | AGOS_AER410W | NP_985265.1 |
Xenopus tropicalis (tropical clawed frog) | top2b | XP_004915443.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.
Philippsen P, Kleine K, P?hlmann R, D?sterh?ft A, Hamberg K, Hegemann JH, Obermaier B, Urrestarazu LA, Aert R, Albermann K, Altmann R, Andr? B, Baladron V, Ballesta JP, B?cam AM, Beinhauer J, Boskovic J, Buitrago MJ, Bussereau F, Coster F, Crouzet M, D'Angelo M, Dal Pero F, De Antoni A, Del Rey F, Doignon F, Domdey H, Dubois E, Fiedler T, Fleig U, Floeth M, Fritz C, Gaillardin C, Garcia-Cantalejo JM, Glansdorff NN, Goffeau A, Gueldener U, Herbert C, Heumann K, Heuss-Neitzel D, Hilbert H, Hinni K, Iraqui Houssaini I, Jacquet M, Jimenez A, Jonniaux JL, Karpfinger L, Lanfranchi G, Lepingle A, Levesque H, Lyck R, Maftahi M, Mallet L, Maurer KC, Messenguy F, Mewes HW, M?sti D, Nasr F, Nicaud JM, Niedenthal RK, Pandolfo D, Pi?rard A, Piravandi E, Planta RJ, Pohl TM, Purnelle B, Rebischung C, Remacha M, Revuelta JL, Rinke M, Saiz JE, Sartorello F, Scherens B, Sen-Gupta M, Soler-Mira A, Urbanus JH, Valle G, Van Dyck L, Verhasselt P, Vierendeels F, Vissers S, Voet M, Volckaert G, Wach A, Wambutt R, Wedler H, Zollner A, Hani J
Nature387(6632 Suppl)93-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Condensin DNA supercoiling activity correlates with Top2 intertwine removal during DNA replication.
Title: Physical Proximity of Sister Chromatids Promotes Top2-Dependent Intertwining.
Our data are consistent with a redundant role of Top2 and Sgs1 together with Top3 (Sgs1-Top3) in replication fork merging at rDNA barriers.
Title: Top2 and Sgs1-Top3 Act Redundantly to Ensure rDNA Replication Termination.
Topoisomerase II plays a central role in a molecular pathway for crossover interference
Title: Topoisomerase II mediates meiotic crossover interference.
Chromatin regulates DNA torsional energy via topoisomerase II-mediated relaxation of positive supercoils.
Title: Chromatin regulates DNA torsional energy via topoisomerase II-mediated relaxation of positive supercoils.
the cell cycle delay depends on the divergent and catalytically inert C-terminal region of Topo II, indicating that transmission of a checkpoint signal may occur via the C-terminus
Title: Direct monitoring of the strand passage reaction of DNA topoisomerase II triggers checkpoint activation.
The following TOP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TOP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04543 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182926.3 | |
Accession Version | NM_001182926.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4287bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | DNA topoisomerase 2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001146). On Jul 30, 2012 this sequence version replaced NM_001182926.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCAACTG AACCGGTAAG CGCCTCTGAT AAATATCAGA AAATTTCTCA ACTGGAACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014311.3 |
CDS | 1..4287 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182926.3 |
1 | ATGTCAACTG AACCGGTAAG CGCCTCTGAT AAATATCAGA AAATTTCTCA ACTGGAACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications. |
Life with 6000 genes. |