Gene Symbol | gcn2 |
Entrez Gene ID | 2540500 |
Full Name | eIF2 alpha kinase Gcn2 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
ORF » Species Summary » Schizosaccharomyces pombe » gcn2 cDNA ORF clone
Gene Symbol | gcn2 |
Entrez Gene ID | 2540500 |
Full Name | eIF2 alpha kinase Gcn2 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
mRNA | Protein | Name |
---|---|---|
NM_001021898.2 | NP_595991.2 | eIF2 alpha kinase Gcn2 |
Pan troglodytes (chimpanzee) | EIF2AK4 | XP_001140245.1 |
EIF2AK4 | XP_002804763.1 | |
Gallus gallus (chicken) | EIF2AK4 | XP_004941777.1 |
Eremothecium gossypii | AGOS_AAL083W | NP_982459.1 |
Rattus norvegicus (Norway rat) | Eif2ak4 | NP_001099214.2 |
Danio rerio (zebrafish) | eif2ak4 | XP_002667149.3 |
Drosophila melanogaster (fruit fly) | Gcn2 | NP_001263141.1 |
Saccharomyces cerevisiae (baker's yeast) | GCN2 | NP_010569.3 |
Kluyveromyces lactis | KLLA0C10802g | XP_452681.1 |
Neurospora crassa | NCU01187 | XP_961553.1 |
Xenopus tropicalis (tropical clawed frog) | eif2ak4 | NP_001243855.1 |
Homo sapiens (human) | EIF2AK4 | NP_001013725.2 |
Canis lupus familiaris (dog) | EIF2AK4 | XP_535431.3 |
Bos taurus (cattle) | EIF2AK4 | XP_002690831.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012368 | XP_320188.4 |
Caenorhabditis elegans (roundworm) | gcn-2 | NP_001254370.1 |
Schizosaccharomyces pombe (fission yeast) | gcn2 | NP_595991.2 |
Mus musculus (house mouse) | Eif2ak4 | NP_038747.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_08643 | XP_003711074.1 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Gcn2 and eIF2a phosphorylation are involved in the modulation of G1 phase cell cycle arrest, cell survival and mating under nutritional stress in the fission yeast Schizosaccharomyces pombe.
Title: New roles of the fission yeast eIF2? kinases Hri1 and Gcn2 in response to nutritional stress.
S. pombe Cpc2 facilitates the GAAC response through the regulation of Gcn2 activation
Title: Receptor for activated C-kinase (RACK1) homolog Cpc2 facilitates the general amino acid control response through Gcn2 kinase in fission yeast.
Gcn2 is the primary eIF2 kinase induced during a nutrient downshift, treatment with the amino acid biosynthetic inhibitor 3-aminotriazole or upon exposure to high NaCl concentrations. It is tandemly activated with Hri2 in response to H2O2 exposure. [Gcn2]
Title: Differential activation of eIF2 kinases in response to cellular stresses in Schizosaccharomyces pombe.
The following gcn2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the gcn2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSc100051 | |
Clone ID Related Accession (Same CDS sequence) | NM_001021898.2 | |
Accession Version | NM_001021898.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4731bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-02 | |
Organism | Schizosaccharomyces pombe(fission yeast) | |
Product | eIF2 alpha kinase Gcn2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003423). On Dec 10, 2012 this sequence version replaced NM_001021898.1. |
1 | ATGGATGCGG CGAAACGTCT GGAACTATGC AAGGAAATTC AAGAAAATGA AATTGAGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_595991.2 |
CDS | 735..5465 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001021898.2 |
1 | ATGGATGCGG CGAAACGTCT GGAACTATGC AAGGAAATTC AAGAAAATGA AATTGAGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |