Gene Symbol | RSP5 |
Entrez Gene ID | 856862 |
Full Name | NEDD4 family E3 ubiquitin-protein ligase |
Synonyms | MDP1,MUT2,NPI1,SMM1,UBY1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » RSP5 cDNA ORF clone
Gene Symbol | RSP5 |
Entrez Gene ID | 856862 |
Full Name | NEDD4 family E3 ubiquitin-protein ligase |
Synonyms | MDP1,MUT2,NPI1,SMM1,UBY1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179015.3 | NP_011051.3 | NEDD4 family E3 ubiquitin-protein ligase |
Pan troglodytes (chimpanzee) | NEDD4L | XP_001140979.1 |
Canis lupus familiaris (dog) | NEDD4L | XP_005615425.1 |
Bos taurus (cattle) | NEDD4L | XP_005224408.1 |
Schizosaccharomyces pombe (fission yeast) | pub1 | NP_594396.1 |
NEDD4L | XP_001088661.2 | |
Gallus gallus (chicken) | NEDD4L | XP_004949055.1 |
Eremothecium gossypii | AGOS_ADL055C | NP_984041.1 |
Neurospora crassa | NCU03947 | XP_957586.2 |
Homo sapiens (human) | NEDD4L | NP_001138439.1 |
Drosophila melanogaster (fruit fly) | Nedd4 | NP_730284.2 |
Xenopus tropicalis (tropical clawed frog) | nedd4l | NP_001006727.1 |
Caenorhabditis elegans (roundworm) | Y92H12A.2 | NP_490865.3 |
Magnaporthe oryzae (rice blast fungus) | MGG_07255 | XP_003715474.1 |
Mus musculus (house mouse) | Nedd4l | NP_001107858.1 |
Rattus norvegicus (Norway rat) | Nedd4l | NP_001008301.2 |
Danio rerio (zebrafish) | nedd4l | XP_005161145.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP000787 | XP_311327.5 |
Saccharomyces cerevisiae (baker's yeast) | RSP5 | NP_011051.3 |
Kluyveromyces lactis | KLLA0E13575g | XP_454562.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Dietrich FS, Mulligan J, Hennessy K, Yelton MA, Allen E, Araujo R, Aviles E, Berno A, Brennan T, Carpenter J, Chen E, Cherry JM, Chung E, Duncan M, Guzman E, Hartzell G, Hunicke-Smith S, Hyman RW, Kayser A, Komp C, Lashkari D, Lew H, Lin D, Mosedale D, Davis RW
Nature387(6632 Suppl)78-81(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Mdm34 and Mdm12, 2 components of the endoplasmic reticulum-mitochondrial encounter structure, are ubiquitinated by the E3 ligase Rsp5
Title: Ubiquitination of ERMES components by the E3 ligase Rsp5 is involved in mitophagy.
Authors present the molecular features in the methionine permease Mup1 that are required for Art1-Rsp5-mediated ubiquitination and endocytosis.
Title: Identification of the endocytic sorting signal recognized by the Art1-Rsp5 ubiquitin ligase complex.
Rsp5 may be phosphorylated by PKA at position T761 and that this regulation is important for its localization and function.
Title: Mimicking the phosphorylation of Rsp5 in PKA site T761 affects its function and cellular localization.
While rsp5(T255A), RSP5(T357A), and rsp5(T413A) impaired the interaction of Rsp5 with Bul1, the RSP5(T357A) mutation specifically augmented the interaction with Bul2.
Title: Cooperative and selective roles of the WW domains of the yeast Nedd4-like ubiquitin ligase Rsp5 in the recognition of the arrestin-like adaptors Bul1 and Bul2.
Hem12 is monoubiquitinated in vivo by Rsp5
Title: Hem12, an enzyme of heme biosynthesis pathway, is monoubiquitinated by Rsp5 ubiquitin ligase in yeast cells.
The following RSP5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RSP5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05620 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179015.3 | |
Accession Version | NM_001179015.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2430bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | NEDD4 family E3 ubiquitin-protein ligase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001137). On Jul 30, 2012 this sequence version replaced NM_001179015.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCCTTCAT CCATATCCGT CAAGTTAGTG GCTGCAGAGT CATTATATAA GAGGGACGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011051.3 |
CDS | 1..2430 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179015.3 |
1 | ATGCCTTCAT CCATATCCGT CAAGTTAGTG GCTGCAGAGT CATTATATAA GAGGGACGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome V. |
Life with 6000 genes. |