Gene Symbol | SERPINA3-7 |
Entrez Gene ID | 497203 |
Full Name | endopin 2 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » SERPINA3-7 cDNA ORF clone
Gene Symbol | SERPINA3-7 |
Entrez Gene ID | 497203 |
Full Name | endopin 2 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_005222134.3 | XP_005222191.1 | serpin A3-7 isoform X1 |
NM_001012283.3 | NP_001012283.2 | serpin A3-7 precursor |
XM_005222134.4 | XP_005222191.1 | serpin A3-7 isoform X1 |
Bos taurus (cattle) | SERPINA3-7 | NP_001012283.2 |
Bos taurus (cattle) | LOC784932 | XP_002696874.1 |
Bos taurus (cattle) | SERPINA3 | XP_005222351.1 |
Mus musculus (house mouse) | Serpina3n | NP_033278.2 |
Homo sapiens (human) | SERPINA3 | NP_001076.2 |
Bos taurus (cattle) | SERPINA3-1 | NP_777193.2 |
Bos taurus (cattle) | SERPINA3-3 | NP_001033293.1 |
Mus musculus (house mouse) | Serpina3c | NP_032484.1 |
Pan troglodytes (chimpanzee) | SERPINA3 | XP_510145.2 |
Mus musculus (house mouse) | Serpina3k | NP_035588.2 |
Mus musculus (house mouse) | Serpina3m | NP_033279.2 |
Rattus norvegicus (Norway rat) | Serpina3n | NP_113719.1 |
SERPINA3 | XP_001096947.2 | |
Canis lupus familiaris (dog) | SERPINA3 | XP_005623829.1 |
Bos taurus (cattle) | SERPINA3-8 | NP_001075181.1 |
Effect of reactive center loop structure of antichymotrypsin on inhibition of duodenase activity.
Zamolodchikova TS, Popykina NA, Gladysheva IP, Larionova NI
Biochemistry. Biokhimiia74(8)824-33(2009 Aug)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Multiple domains of endopin 2A for serpin cross-class inhibition of papain.
Hwang SR, Hook VY
Archives of biochemistry and biophysics461(2)219-24(2007 May)
The novel bovine serpin endopin 2C demonstrates selective inhibition of the cysteine protease cathepsin L compared to the serine protease elastase, in cross-class inhibition.
Hwang SR, Stoka V, Turk V, Hook VY
Biochemistry44(21)7757-67(2005 May)
Demonstration of GTG as an alternative initiation codon for the serpin endopin 2B-2.
Hwang SR, Garza CZ, Wegrzyn JL, Hook VY
Biochemical and biophysical research communications327(3)837-44(2005 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Duodenase interacted with P1 variants of antichymotrypsin via a suicide mechanism with stoichiometry of the process SI = 1.2.
Title: Effect of reactive center loop structure of antichymotrypsin on inhibition of duodenase activity.
NH2-terminal domain and the reactive site loop region both participate in endopin 2A inhibition of papain.
Title: Multiple domains of endopin 2A for serpin cross-class inhibition of papain.
Molecular cloning revealed the unique serpin endopin 2C that demonstrates selective inhibition of cathepsin L compared to papain or elastase. Endopin 2C, thus, functions as a serpin with the property of cross-class inhibition.
Title: The novel bovine serpin endopin 2C demonstrates selective inhibition of the cysteine protease cathepsin L compared to the serine protease elastase, in cross-class inhibition.
The following SERPINA3-7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SERPINA3-7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa42108 | |
Clone ID Related Accession (Same CDS sequence) | NM_001012283.3 | |
Accession Version | NM_001012283.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1254bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-07 | |
Organism | Bos taurus(cattle) | |
Product | serpin A3-7 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC102746.1. On Oct 26, 2014 this sequence version replaced NM_001012283.2. ##Evidence-Data-START## Transcript exon combination :: BC102746.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN03145419, SAMN03145425 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGAGGACAG AGAGAACTTC CTTCCTCCTG GCTCTGGGGC TCCTGGTGTC TGGGTTCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001012283.2 |
CDS | 61..1314 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001012283.3 |
1 | ATGAGGACAG AGAGAACTTC CTTCCTCCTG GCTCTGGGGC TCCTGGTGTC TGGGTTCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa31062 | |
Clone ID Related Accession (Same CDS sequence) | XM_005222134.3 , XM_005222134.4 | |
Accession Version | XM_005222134.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1254bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | serpin A3-7 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 26, 2016 this sequence version replaced XM_005222134.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGGACAG AGAGAACTTC CTTCCTCCTG GCTCTGGGGC TCCTGGTGTC TGGGTTCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005222191.1 |
CDS | 118..1371 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005222134.3 |
1 | ATGAGGACAG AGAGAACTTC CTTCCTCCTG GCTCTGGGGC TCCTGGTGTC TGGGTTCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa31062 | |
Clone ID Related Accession (Same CDS sequence) | XM_005222134.3 , XM_005222134.4 | |
Accession Version | XM_005222134.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1254bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | serpin A3-7 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037348.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_005222134.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGGACAG AGAGAACTTC CTTCCTCCTG GCTCTGGGGC TCCTGGTGTC TGGGTTCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005222191.1 |
CDS | 63..1316 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005222134.4 |
1 | ATGAGGACAG AGAGAACTTC CTTCCTCCTG GCTCTGGGGC TCCTGGTGTC TGGGTTCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Effect of reactive center loop structure of antichymotrypsin on inhibition of duodenase activity. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Multiple domains of endopin 2A for serpin cross-class inhibition of papain. |
The novel bovine serpin endopin 2C demonstrates selective inhibition of the cysteine protease cathepsin L compared to the serine protease elastase, in cross-class inhibition. |
Demonstration of GTG as an alternative initiation codon for the serpin endopin 2B-2. |