Gene Symbol | SERPINA3-3 |
Entrez Gene ID | 615103 |
Full Name | endopin 1b |
Synonyms | SERPINA3-4 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » SERPINA3-3 cDNA ORF clone
Gene Symbol | SERPINA3-3 |
Entrez Gene ID | 615103 |
Full Name | endopin 1b |
Synonyms | SERPINA3-4 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_024981937.1 | XP_024837705.1 | serpin A3-3 isoform X2 |
NM_001038204.2 | NP_001033293.1 | serpin A3-3 precursor |
XM_024981936.1 | XP_024837704.1 | serpin A3-3 isoform X1 |
XM_024981938.1 | XP_024837706.1 | serpin A3-3 isoform X2 |
Bos taurus (cattle) | SERPINA3-7 | NP_001012283.2 |
Bos taurus (cattle) | LOC784932 | XP_002696874.1 |
Bos taurus (cattle) | SERPINA3 | XP_005222351.1 |
Mus musculus (house mouse) | Serpina3n | NP_033278.2 |
Homo sapiens (human) | SERPINA3 | NP_001076.2 |
Bos taurus (cattle) | SERPINA3-1 | NP_777193.2 |
Bos taurus (cattle) | SERPINA3-3 | NP_001033293.1 |
Mus musculus (house mouse) | Serpina3c | NP_032484.1 |
Pan troglodytes (chimpanzee) | SERPINA3 | XP_510145.2 |
Mus musculus (house mouse) | Serpina3k | NP_035588.2 |
Mus musculus (house mouse) | Serpina3m | NP_033279.2 |
Rattus norvegicus (Norway rat) | Serpina3n | NP_113719.1 |
SERPINA3 | XP_001096947.2 | |
Canis lupus familiaris (dog) | SERPINA3 | XP_005623829.1 |
Bos taurus (cattle) | SERPINA3-8 | NP_001075181.1 |
Mutagenesis of the bovSERPINA3-3 demonstrates the requirement of aspartate-371 for intermolecular interaction and formation of dimers.
Blanchet X, P?r?-Brissaud A, Duprat N, Pinault E, Delourme D, Ouali A, Combet C, Maftah A, P?lissier P, Br?maud L
Protein science : a publication of the Protein Society21(7)977-86(2012 Jul)
Inhibition of human initiator caspase 8 and effector caspase 3 by cross-class inhibitory bovSERPINA3-1 and A3-3.
Herrera-Mendez CH, Becila S, Blanchet X, Pelissier P, Delourme D, Coulis G, Sentandreu MA, Boudjellal A, Bremaud L, Ouali A
FEBS letters583(17)2743-8(2009 Sep)
An original SERPINA3 gene cluster: elucidation of genomic organization and gene expression in the Bos taurus 21q24 region.
Pelissier P, Delourme D, Germot A, Blanchet X, Becila S, Maftah A, Leveziel H, Ouali A, Bremaud L
BMC genomics9151(2008 Apr)
Purification of the skeletal muscle protein Endopin 1B and characterization of the genes encoding Endopin 1A and 1B isoforms.
Herrera-Mendez CH, Br?maud L, Coulis G, P?lissier P, Sentandreu MA, Aubry L, Delourme D, Chambon C, Maftah A, Leveziel H, Ouali A
FEBS letters580(14)3477-84(2006 Jun)
Unique reactive site domains of neuroendocrine isoforms of alpha 1-antichymotrypsin from bovine adrenal medulla and pituitary revealed by molecular cloning.
Hwang SR, Kohn AB, Hook VY
FEBS letters368(3)471-6(1995 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
In this report, by site-directed mutagenesis of recombinant SERPINA3-3, with substitution D371A, the study demonstrates the importance of D371 for the intermolecular linkage observed in denaturing and reducing conditions.
Title: Mutagenesis of the bovSERPINA3-3 demonstrates the requirement of aspartate-371 for intermolecular interaction and formation of dimers.
Data demonstrate the strong inhibition of human initiator and effector caspases 3 and 8 by bovine SERPINA3-1 and A3-3.
Title: Inhibition of human initiator caspase 8 and effector caspase 3 by cross-class inhibitory bovSERPINA3-1 and A3-3.
The following SERPINA3-3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SERPINA3-3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa42924 | |
Clone ID Related Accession (Same CDS sequence) | NM_001038204.2 | |
Accession Version | NM_001038204.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1236bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-20 | |
Organism | Bos taurus(cattle) | |
Product | serpin A3-3 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC111356.1. On Oct 26, 2014 this sequence version replaced NM_001038204.1. ##Evidence-Data-START## Transcript exon combination :: BC111356.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04019641 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAGGGCAG AGAGACTGTC CCCCCTCCTG GCTCTGGGGC TCCTGGTGGC TGGGATCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001033293.1 |
CDS | 148..1383 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001038204.2 |
1 | ATGAGGGCAG AGAGACTGTC CCCCCTCCTG GCTCTGGGGC TCCTGGTGGC TGGGATCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa31143 | |
Clone ID Related Accession (Same CDS sequence) | XM_024981936.1 | |
Accession Version | XM_024981936.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | serpin A3-3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037348.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGACTG CGGATCCATC CCCACCTCCC GCTCTCACAG ACATGAGGGC AGAGAGACTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024837704.1 |
CDS | 45..1322 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024981936.1 |
1 | ATGGTGACTG CGGATCCATC CCCACCTCCC GCTCTCACAG ACATGAGGGC AGAGAGACTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa31144 | |
Clone ID Related Accession (Same CDS sequence) | XM_024981937.1 , XM_024981938.1 | |
Accession Version | XM_024981937.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1236bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | serpin A3-3 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037348.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGGGCAG AGAGACTGTC CCCCCTCCTG GCTCTGGGGC TCCTGGTGGC TGGGATCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024837705.1 |
CDS | 161..1396 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024981937.1 |
1 | ATGAGGGCAG AGAGACTGTC CCCCCTCCTG GCTCTGGGGC TCCTGGTGGC TGGGATCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa31144 | |
Clone ID Related Accession (Same CDS sequence) | XM_024981937.1 , XM_024981938.1 | |
Accession Version | XM_024981938.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1236bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | serpin A3-3 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037348.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGGGCAG AGAGACTGTC CCCCCTCCTG GCTCTGGGGC TCCTGGTGGC TGGGATCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024837706.1 |
CDS | 97..1332 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024981938.1 |
1 | ATGAGGGCAG AGAGACTGTC CCCCCTCCTG GCTCTGGGGC TCCTGGTGGC TGGGATCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mutagenesis of the bovSERPINA3-3 demonstrates the requirement of aspartate-371 for intermolecular interaction and formation of dimers. |
Inhibition of human initiator caspase 8 and effector caspase 3 by cross-class inhibitory bovSERPINA3-1 and A3-3. |
An original SERPINA3 gene cluster: elucidation of genomic organization and gene expression in the Bos taurus 21q24 region. |
Purification of the skeletal muscle protein Endopin 1B and characterization of the genes encoding Endopin 1A and 1B isoforms. |
Unique reactive site domains of neuroendocrine isoforms of alpha 1-antichymotrypsin from bovine adrenal medulla and pituitary revealed by molecular cloning. |