Gene Symbol | AFF4 |
Entrez Gene ID | 27125 |
Full Name | AF4/FMR2 family member 4 |
Synonyms | AF5Q31,CHOPS,MCEF |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011]. |
Disorder MIM: | |
Disorder Html: | CHOPS syndrome, 616368 (3) |