GJA1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GJA1
Entrez Gene ID	2697
Full Name	gap junction protein alpha 1
Synonyms	AVSD3,CMDR,CX43,EKVP,EKVP3,GJAL,HLHS1,HSS,ODDD,PPKCA
General protein information	Preferred Names gap junction protein alpha 1 Names gap junction alpha-1 protein connexin-43 gap junction 43 kDa heart protein gap junction protein, alpha 1, 43kDa
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q22.31
Summary	This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014].
Disorder MIM:	121014
Disorder Html:	Oculodentodigital dysplasia, 164200 (3); Syndactyly, type III, 186100 (3); Hypoplastic left heart syndrome 1, 241550 (3); Atrioventricular septal defect 3, 600309 (3); Oculodentodigital dysplasia, autosomal recessive, 257850 (3); Craniometaphyseal dysplasia, autosomal recessive, 218400 (3); Erythrokeratodermia variabilis et progressiva 3, 617525 (3); Palmoplantar keratoderma with congenital alopecia, 104100 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000165.4	NP_000156.1	gap junction alpha-1 protein
NM_000165.5	NP_000156.1	gap junction alpha-1 protein

Pathways from BioSystems

Homologies

	GJA1	XP_001109617.1
Mus musculus (house mouse)	Gja1	NP_034418.1
Xenopus tropicalis (tropical clawed frog)	gja1	NP_988856.1
Pan troglodytes (chimpanzee)	GJA1	XP_001164338.1
Canis lupus familiaris (dog)	GJA1	NP_001002951.2
Bos taurus (cattle)	GJA1	NP_776493.1
Rattus norvegicus (Norway rat)	Gja1	NP_036699.1
Homo sapiens (human)	GJA1	NP_000156.1
Gallus gallus (chicken)	GJA1	NP_989917.1
Danio rerio (zebrafish)	cx43	NP_571113.1

Gene Ontology

The following GJA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GJA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24686	NM_000165.5 Latest version!	Homo sapiens gap junction protein alpha 1 (GJA1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu24686	NM_000165.4	Homo sapiens gap junction protein alpha 1 (GJA1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GJA1 ( NM_000165.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000156.1 Homo sapiens gap junction protein alpha 1 (GJA1), mRNA.

Price & Availability↑

CloneID	OHu24686
Clone ID Related Accession (Same CDS sequence)	NM_000165.4 , NM_000165.5
Accession Version	NM_000165.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1149bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Homo sapiens(human)
Product	gap junction alpha-1 protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP226987.1, BC026329.1, AL139098.15 and AW664595.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2014 this sequence version replaced NM_000165.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BP226987.1, SRR1803614.274105.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGTGACT GGAGCGCCTT AGGCAAACTC CTTGACAAGG TTCAAGCCTA CTCAACTGCT 
GGAGGGAAGG TGTGGCTGTC AGTACTTTTC ATTTTCCGAA TCCTGCTGCT GGGGACAGCG 
GTTGAGTCAG CCTGGGGAGA TGAGCAGTCT GCCTTTCGTT GTAACACTCA GCAACCTGGT 
TGTGAAAATG TCTGCTATGA CAAGTCTTTC CCAATCTCTC ATGTGCGCTT CTGGGTCCTG 
CAGATCATAT TTGTGTCTGT ACCCACACTC TTGTACCTGG CTCATGTGTT CTATGTGATG 
CGAAAGGAAG AGAAACTGAA CAAGAAAGAG GAAGAACTCA AGGTTGCCCA AACTGATGGT 
GTCAATGTGG ACATGCACTT GAAGCAGATT GAGATAAAGA AGTTCAAGTA CGGTATTGAA 
GAGCATGGTA AGGTGAAAAT GCGAGGGGGG TTGCTGCGAA CCTACATCAT CAGTATCCTC 
TTCAAGTCTA TCTTTGAGGT GGCCTTCTTG CTGATCCAGT GGTACATCTA TGGATTCAGC 
TTGAGTGCTG TTTACACTTG CAAAAGAGAT CCCTGCCCAC ATCAGGTGGA CTGTTTCCTC 
TCTCGCCCCA CGGAGAAAAC CATCTTCATC ATCTTCATGC TGGTGGTGTC CTTGGTGTCC 
CTGGCCTTGA ATATCATTGA ACTCTTCTAT GTTTTCTTCA AGGGCGTTAA GGATCGGGTT 
AAGGGAAAGA GCGACCCTTA CCATGCGACC AGTGGTGCGC TGAGCCCTGC CAAAGACTGT 
GGGTCTCAAA AATATGCTTA TTTCAATGGC TGCTCCTCAC CAACCGCTCC CCTCTCGCCT 
ATGTCTCCTC CTGGGTACAA GCTGGTTACT GGCGACAGAA ACAATTCTTC TTGCCGCAAT 
TACAACAAGC AAGCAAGTGA GCAAAACTGG GCTAATTACA GTGCAGAACA AAATCGAATG 
GGGCAGGCGG GAAGCACCAT CTCTAACTCC CATGCACAGC CTTTTGATTT CCCCGATGAT 
AACCAGAATT CTAAAAAACT AGCTGCTGGA CATGAATTAC AGCCACTAGC CATTGTGGAC 
CAGCGACCTT CAAGCAGAGC CAGCAGTCGT GCCAGCAGCA GACCTCGGCC TGATGACCTG 
GAGATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000156.1
CDS	273..1421
Translation	MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI

Target ORF information:

RefSeq Version	NM_000165.4
Organism	Homo sapiens(human)
Definition	Homo sapiens gap junction protein alpha 1 (GJA1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000165.4

ORF Insert Sequence:

ATGGGTGACT GGAGCGCCTT AGGCAAACTC CTTGACAAGG TTCAAGCCTA CTCAACTGCT 
GGAGGGAAGG TGTGGCTGTC AGTACTTTTC ATTTTCCGAA TCCTGCTGCT GGGGACAGCG 
GTTGAGTCAG CCTGGGGAGA TGAGCAGTCT GCCTTTCGTT GTAACACTCA GCAACCTGGT 
TGTGAAAATG TCTGCTATGA CAAGTCTTTC CCAATCTCTC ATGTGCGCTT CTGGGTCCTG 
CAGATCATAT TTGTGTCTGT ACCCACACTC TTGTACCTGG CTCATGTGTT CTATGTGATG 
CGAAAGGAAG AGAAACTGAA CAAGAAAGAG GAAGAACTCA AGGTTGCCCA AACTGATGGT 
GTCAATGTGG ACATGCACTT GAAGCAGATT GAGATAAAGA AGTTCAAGTA CGGTATTGAA 
GAGCATGGTA AGGTGAAAAT GCGAGGGGGG TTGCTGCGAA CCTACATCAT CAGTATCCTC 
TTCAAGTCTA TCTTTGAGGT GGCCTTCTTG CTGATCCAGT GGTACATCTA TGGATTCAGC 
TTGAGTGCTG TTTACACTTG CAAAAGAGAT CCCTGCCCAC ATCAGGTGGA CTGTTTCCTC 
TCTCGCCCCA CGGAGAAAAC CATCTTCATC ATCTTCATGC TGGTGGTGTC CTTGGTGTCC 
CTGGCCTTGA ATATCATTGA ACTCTTCTAT GTTTTCTTCA AGGGCGTTAA GGATCGGGTT 
AAGGGAAAGA GCGACCCTTA CCATGCGACC AGTGGTGCGC TGAGCCCTGC CAAAGACTGT 
GGGTCTCAAA AATATGCTTA TTTCAATGGC TGCTCCTCAC CAACCGCTCC CCTCTCGCCT 
ATGTCTCCTC CTGGGTACAA GCTGGTTACT GGCGACAGAA ACAATTCTTC TTGCCGCAAT 
TACAACAAGC AAGCAAGTGA GCAAAACTGG GCTAATTACA GTGCAGAACA AAATCGAATG 
GGGCAGGCGG GAAGCACCAT CTCTAACTCC CATGCACAGC CTTTTGATTT CCCCGATGAT 
AACCAGAATT CTAAAAAACT AGCTGCTGGA CATGAATTAC AGCCACTAGC CATTGTGGAC 
CAGCGACCTT CAAGCAGAGC CAGCAGTCGT GCCAGCAGCA GACCTCGGCC TGATGACCTG 
GAGATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GJA1 ( NM_000165.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_000156.1 Homo sapiens gap junction protein alpha 1 (GJA1), mRNA.

Price & Availability↑

CloneID	OHu24686
Clone ID Related Accession (Same CDS sequence)	NM_000165.4 , NM_000165.5
Accession Version	NM_000165.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1149bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	gap junction alpha-1 protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP226987.1, BC026329.1, AL139098.15 and AW664595.1. This sequence is a reference standard in the RefSeqGene project. On Oct 3, 2018 this sequence version replaced NM_000165.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.188866.1, SRR1660803.132563.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000282561.4/ ENSP00000282561.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGTGACT GGAGCGCCTT AGGCAAACTC CTTGACAAGG TTCAAGCCTA CTCAACTGCT 
GGAGGGAAGG TGTGGCTGTC AGTACTTTTC ATTTTCCGAA TCCTGCTGCT GGGGACAGCG 
GTTGAGTCAG CCTGGGGAGA TGAGCAGTCT GCCTTTCGTT GTAACACTCA GCAACCTGGT 
TGTGAAAATG TCTGCTATGA CAAGTCTTTC CCAATCTCTC ATGTGCGCTT CTGGGTCCTG 
CAGATCATAT TTGTGTCTGT ACCCACACTC TTGTACCTGG CTCATGTGTT CTATGTGATG 
CGAAAGGAAG AGAAACTGAA CAAGAAAGAG GAAGAACTCA AGGTTGCCCA AACTGATGGT 
GTCAATGTGG ACATGCACTT GAAGCAGATT GAGATAAAGA AGTTCAAGTA CGGTATTGAA 
GAGCATGGTA AGGTGAAAAT GCGAGGGGGG TTGCTGCGAA CCTACATCAT CAGTATCCTC 
TTCAAGTCTA TCTTTGAGGT GGCCTTCTTG CTGATCCAGT GGTACATCTA TGGATTCAGC 
TTGAGTGCTG TTTACACTTG CAAAAGAGAT CCCTGCCCAC ATCAGGTGGA CTGTTTCCTC 
TCTCGCCCCA CGGAGAAAAC CATCTTCATC ATCTTCATGC TGGTGGTGTC CTTGGTGTCC 
CTGGCCTTGA ATATCATTGA ACTCTTCTAT GTTTTCTTCA AGGGCGTTAA GGATCGGGTT 
AAGGGAAAGA GCGACCCTTA CCATGCGACC AGTGGTGCGC TGAGCCCTGC CAAAGACTGT 
GGGTCTCAAA AATATGCTTA TTTCAATGGC TGCTCCTCAC CAACCGCTCC CCTCTCGCCT 
ATGTCTCCTC CTGGGTACAA GCTGGTTACT GGCGACAGAA ACAATTCTTC TTGCCGCAAT 
TACAACAAGC AAGCAAGTGA GCAAAACTGG GCTAATTACA GTGCAGAACA AAATCGAATG 
GGGCAGGCGG GAAGCACCAT CTCTAACTCC CATGCACAGC CTTTTGATTT CCCCGATGAT 
AACCAGAATT CTAAAAAACT AGCTGCTGGA CATGAATTAC AGCCACTAGC CATTGTGGAC 
CAGCGACCTT CAAGCAGAGC CAGCAGTCGT GCCAGCAGCA GACCTCGGCC TGATGACCTG 
GAGATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000156.1
CDS	204..1352
Translation	MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI

Target ORF information:

RefSeq Version	NM_000165.5
Organism	Homo sapiens(human)
Definition	Homo sapiens gap junction protein alpha 1 (GJA1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000165.5

ORF Insert Sequence:

ATGGGTGACT GGAGCGCCTT AGGCAAACTC CTTGACAAGG TTCAAGCCTA CTCAACTGCT 
GGAGGGAAGG TGTGGCTGTC AGTACTTTTC ATTTTCCGAA TCCTGCTGCT GGGGACAGCG 
GTTGAGTCAG CCTGGGGAGA TGAGCAGTCT GCCTTTCGTT GTAACACTCA GCAACCTGGT 
TGTGAAAATG TCTGCTATGA CAAGTCTTTC CCAATCTCTC ATGTGCGCTT CTGGGTCCTG 
CAGATCATAT TTGTGTCTGT ACCCACACTC TTGTACCTGG CTCATGTGTT CTATGTGATG 
CGAAAGGAAG AGAAACTGAA CAAGAAAGAG GAAGAACTCA AGGTTGCCCA AACTGATGGT 
GTCAATGTGG ACATGCACTT GAAGCAGATT GAGATAAAGA AGTTCAAGTA CGGTATTGAA 
GAGCATGGTA AGGTGAAAAT GCGAGGGGGG TTGCTGCGAA CCTACATCAT CAGTATCCTC 
TTCAAGTCTA TCTTTGAGGT GGCCTTCTTG CTGATCCAGT GGTACATCTA TGGATTCAGC 
TTGAGTGCTG TTTACACTTG CAAAAGAGAT CCCTGCCCAC ATCAGGTGGA CTGTTTCCTC 
TCTCGCCCCA CGGAGAAAAC CATCTTCATC ATCTTCATGC TGGTGGTGTC CTTGGTGTCC 
CTGGCCTTGA ATATCATTGA ACTCTTCTAT GTTTTCTTCA AGGGCGTTAA GGATCGGGTT 
AAGGGAAAGA GCGACCCTTA CCATGCGACC AGTGGTGCGC TGAGCCCTGC CAAAGACTGT 
GGGTCTCAAA AATATGCTTA TTTCAATGGC TGCTCCTCAC CAACCGCTCC CCTCTCGCCT 
ATGTCTCCTC CTGGGTACAA GCTGGTTACT GGCGACAGAA ACAATTCTTC TTGCCGCAAT 
TACAACAAGC AAGCAAGTGA GCAAAACTGG GCTAATTACA GTGCAGAACA AAATCGAATG 
GGGCAGGCGG GAAGCACCAT CTCTAACTCC CATGCACAGC CTTTTGATTT CCCCGATGAT 
AACCAGAATT CTAAAAAACT AGCTGCTGGA CATGAATTAC AGCCACTAGC CATTGTGGAC 
CAGCGACCTT CAAGCAGAGC CAGCAGTCGT GCCAGCAGCA GACCTCGGCC TGATGACCTG 
GAGATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

GJA1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報