SH3BP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SH3BP2
Entrez Gene ID	6452
Full Name	SH3 domain binding protein 2
Synonyms	3BP-2,3BP2,CRBM,CRPM,RES4-23
General protein information	Preferred Names SH3 domain binding protein 2 Names SH3 domain-binding protein 2 Abl-SH3 binding protein 2 TNFAIP3 interacting protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4p16.3
Summary	The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
Disorder MIM:	602104
Disorder Html:	Cherubism, 118400 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_003023.4	NP_003014.3	SH3 domain-binding protein 2 isoform a
NM_001145856.1	NP_001139328.1	SH3 domain-binding protein 2 isoform b
NM_001122681.1	NP_001116153.1	SH3 domain-binding protein 2 isoform a
NM_001145856.2	NP_001139328.1	SH3 domain-binding protein 2 isoform b
NM_001145855.1	NP_001139327.1	SH3 domain-binding protein 2 isoform c
NM_001145855.2	NP_001139327.1	SH3 domain-binding protein 2 isoform c
NM_001122681.2	NP_001116153.1	SH3 domain-binding protein 2 isoform a

Pathways from BioSystems

Homologies

Homo sapiens (human)	SH3BP2	NP_001139328.1
Mus musculus (house mouse)	Sh3bp2	NP_001139331.1
Rattus norvegicus (Norway rat)	Sh3bp2	NP_001094154.1
Gallus gallus (chicken)	SH3BP2	NP_001026336.1
Canis lupus familiaris (dog)	SH3BP2	XP_005618564.1
Pan troglodytes (chimpanzee)	LOC750514	XP_003950326.1
	SH3BP2	XP_001088909.2
Bos taurus (cattle)	SH3BP2	NP_001178455.1

Gene Ontology
Bibliography

Related articles in PubMed

Clinicopathologic and Molecular Characteristics of Familial Cherubism with Associated Odontogenic Tumorous Proliferations.
Argyris PP, Gopalakrishnan R, Hu Y, Reichenberger EJ, Koutlas IG
Head and neck pathology(2017 Jul)

The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival.
Ainsua-Enrich E, Serrano-Candelas E, ?lvarez-Errico D, Picado C, Say?s J, Rivera J, Mart?n M
Journal of immunology (Baltimore, Md. : 1950)194(9)4309-18(2015 May)

A c.1244G>A (p.Arg415Gln) mutation in SH3BP2 gene causes cherubism in a Turkish family: report of a family with review of the literature.
Sekerci AE, Balta B, Dundar M, Hu Y, Reichenberger EJ, Etoz OA, Nazlim S, Bayrakdar IS
Medicina oral, patologia oral y cirugia bucal19(4)e340-4(2014 Jul)

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.
Leung KK, Hause RJ Jr, Barkinge JL, Ciaccio MF, Chuu CP, Jones RB
Molecular & cellular proteomics : MCP13(7)1705-23(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival.
Title: The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival.

A c.1244G>A (p.Arg415Gln) mutation in SH3BP2 gene causes cherubism in a Turkish family
Title: A c.1244G>A (p.Arg415Gln) mutation in SH3BP2 gene causes cherubism in a Turkish family: report of a family with review of the literature.

Authors conclude that a novel p.Asp419Tyr alteration in SH3BP2 to be a cherubism-causing mutation in a Turkish family.
Title: A novel c.1255G>T (p.D419Y) mutation in SH3BP2 gene causes cherubism in a Turkish family.

These results demonstrate that PARP1 regulates expression of SH3BP2.
Title: Cloning and characterization of the human SH3BP2 promoter.

In the first family, a missense mutation Arg415Gln was found in exon 9 of SH3BP2 in all affected individuals. The unaffected individuals did not have the mutation. In the second family, a missense mutation Pro418Thr was identified in exon 9 of the SH3BP2
Title: Mutations of the SH3BP2 gene in 2 families of cherubism.

The following SH3BP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SH3BP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16490	NM_001122681.2 Latest version!	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu16490	NM_003023.4 Latest version!	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu22670	NM_001145855.2 Latest version!	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$349.30 $499.00
OHu23162	NM_001145856.2 Latest version!	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OHu23162	NM_001145856.1	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu22670	NM_001145855.1	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$349.30 $499.00
OHu16490	NM_001122681.1	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SH3BP2 ( NM_003023.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003014.3 Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16490
Clone ID Related Accession (Same CDS sequence)	NM_003023.4 , NM_001122681.1 , NM_001122681.2
Accession Version	NM_003023.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Homo sapiens(human)
Product	SH3 domain-binding protein 2 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB000462.1, AK312286.1 and AL121750.22. On Mar 15, 2008 this sequence version replaced NM_003023.3. Transcript Variant: This variant (1) represents use of an alternative promoter and 5' UTR and uses a downstream translation start site, compared to variant 3. The resulting isoform (a) has a shorter N-terminus, compared to isoform b. Both variants 1 and 2 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB000462.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTG AAGAGATGCA TTGGCCTGTC CCTATGAAGG CCATTGGTGC CCAGAACCTG 
CTAACCATGC CTGGGGGCGT GGCCAAGGCT GGCTACCTGC ACAAGAAGGG CGGTACCCAG 
CTGCAGCTGC TGAAATGGCC CCTGCGCTTT GTCATCATCC ACAAACGCTG CGTCTACTAC 
TTCAAGAGTA GCACCTCTGC CTCCCCGCAG GGCGCCTTCT CCCTGAGTGG CTATAACCGG 
GTGATGCGGG CGGCTGAGGA GACCACGTCC AACAACGTTT TCCCCTTCAA GATCATCCAT 
ATCAGCAAGA AGCACCGCAC GTGGTTCTTC TCGGCCTCCT CCGAGGAGGA GCGCAAGAGC 
TGGATGGCCT TGCTGCGCAG GGAGATTGGC CACTTCCACG AAAAGAAAGA CCTGCCCTTG 
GACACCAGCG ACTCCAGCTC GGACACAGAC AGCTTCTACG GCGCAGTTGA GCGGCCTGTG 
GATATCAGCC TTTCCCCGTA CCCCACGGAC AATGAAGACT ATGAGCACGA CGATGAGGAT 
GACTCCTACC TGGAGCCTGA CTCCCCGGAG CCCGGAAGGC TTGAGGATGC CCTGATGCAC 
CCACCGGCTT ACCCACCACC CCCAGTGCCC ACGCCCAGGA AGCCAGCCTT CTCTGACATG 
CCCCGGGCCC ACTCCTTTAC CTCCAAGGGC CCCGGTCCCC TACTGCCACC CCCGCCCCCT 
AAGCACGGCC TCCCAGATGT TGGCCTGGCT GCTGAGGACT CCAAGAGGGA CCCACTGTGC 
CCGAGGCGGG CTGAGCCTTG CCCCAGGGTA CCTGCTACCC CCCGAAGGAT GAGCGATCCC 
CCTCTGAGCA CCATGCCCAC CGCACCCGGC CTCCGGAAAC CCCCTTGCTT CCGGGAGAGT 
GCCAGCCCCA GCCCGGAGCC CTGGACCCCT GGCCACGGGG CCTGCTCCAC TTCCAGTGCT 
GCCATCATGG CCACTGCCAC CTCCAGAAAC TGTGACAAAC TCAAGTCCTT CCACCTGTCC 
CCCCGAGGAC CACCCACATC TGAGCCCCCA CCTGTGCCAG CCAACAAGCC CAAGTTCCTG 
AAGATAGCTG AAGAGGACCC CCCAAGGGAG GCAGCCATGC CCGGACTCTT TGTGCCCCCC 
GTGGCTCCCC GGCCTCCTGC GCTGAAGCTG CCAGTGCCTG AGGCCATGGC GCGGCCCGCA 
GTCCTGCCCA GGCCAGAGAA GCCGCAGCTC CCGCACCTCC AGCGATCACC CCCCGATGGG 
CAGAGTTTCA GGAGCTTCTC CTTTGAAAAG CCCCGGCAAC CCTCACAGGC TGACACTGGC 
GGGGACGACT CGGACGAGGA CTATGAGAAG GTGCCACTGC CCAACTCGGT CTTCGTCAAC 
ACCACGGAGT CCTGCGAAGT GGAAAGGTTG TTCAAGGCTA CAAGCCCCCG GGGAGAGCCC 
CAGGATGGAC TCTACTGCAT CCGGAACTCC TCTACCAAGT CGGGGAAGGT CCTGGTTGTG 
TGGGACGAAA CCTCTAACAA AGTGAGGAAC TATCGCATTT TTGAGAAGGA CTCTAAGTTC 
TACCTGGAGG GCGAGGTCCT GTTTGTGAGT GTGGGCAGCA TGGTGGAGCA CTACCACACC 
CACGTGCTGC CCAGCCACCA GAGCCTGCTG CTGCGGCACC CCTACGGCTA CACTGGGCCT 
AGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003014.3
CDS	262..1947
Translation	MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR

Target ORF information:

RefSeq Version	NM_003023.4
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003023.4

ORF Insert Sequence:

ATGGCGGCTG AAGAGATGCA TTGGCCTGTC CCTATGAAGG CCATTGGTGC CCAGAACCTG 
CTAACCATGC CTGGGGGCGT GGCCAAGGCT GGCTACCTGC ACAAGAAGGG CGGTACCCAG 
CTGCAGCTGC TGAAATGGCC CCTGCGCTTT GTCATCATCC ACAAACGCTG CGTCTACTAC 
TTCAAGAGTA GCACCTCTGC CTCCCCGCAG GGCGCCTTCT CCCTGAGTGG CTATAACCGG 
GTGATGCGGG CGGCTGAGGA GACCACGTCC AACAACGTTT TCCCCTTCAA GATCATCCAT 
ATCAGCAAGA AGCACCGCAC GTGGTTCTTC TCGGCCTCCT CCGAGGAGGA GCGCAAGAGC 
TGGATGGCCT TGCTGCGCAG GGAGATTGGC CACTTCCACG AAAAGAAAGA CCTGCCCTTG 
GACACCAGCG ACTCCAGCTC GGACACAGAC AGCTTCTACG GCGCAGTTGA GCGGCCTGTG 
GATATCAGCC TTTCCCCGTA CCCCACGGAC AATGAAGACT ATGAGCACGA CGATGAGGAT 
GACTCCTACC TGGAGCCTGA CTCCCCGGAG CCCGGAAGGC TTGAGGATGC CCTGATGCAC 
CCACCGGCTT ACCCACCACC CCCAGTGCCC ACGCCCAGGA AGCCAGCCTT CTCTGACATG 
CCCCGGGCCC ACTCCTTTAC CTCCAAGGGC CCCGGTCCCC TACTGCCACC CCCGCCCCCT 
AAGCACGGCC TCCCAGATGT TGGCCTGGCT GCTGAGGACT CCAAGAGGGA CCCACTGTGC 
CCGAGGCGGG CTGAGCCTTG CCCCAGGGTA CCTGCTACCC CCCGAAGGAT GAGCGATCCC 
CCTCTGAGCA CCATGCCCAC CGCACCCGGC CTCCGGAAAC CCCCTTGCTT CCGGGAGAGT 
GCCAGCCCCA GCCCGGAGCC CTGGACCCCT GGCCACGGGG CCTGCTCCAC TTCCAGTGCT 
GCCATCATGG CCACTGCCAC CTCCAGAAAC TGTGACAAAC TCAAGTCCTT CCACCTGTCC 
CCCCGAGGAC CACCCACATC TGAGCCCCCA CCTGTGCCAG CCAACAAGCC CAAGTTCCTG 
AAGATAGCTG AAGAGGACCC CCCAAGGGAG GCAGCCATGC CCGGACTCTT TGTGCCCCCC 
GTGGCTCCCC GGCCTCCTGC GCTGAAGCTG CCAGTGCCTG AGGCCATGGC GCGGCCCGCA 
GTCCTGCCCA GGCCAGAGAA GCCGCAGCTC CCGCACCTCC AGCGATCACC CCCCGATGGG 
CAGAGTTTCA GGAGCTTCTC CTTTGAAAAG CCCCGGCAAC CCTCACAGGC TGACACTGGC 
GGGGACGACT CGGACGAGGA CTATGAGAAG GTGCCACTGC CCAACTCGGT CTTCGTCAAC 
ACCACGGAGT CCTGCGAAGT GGAAAGGTTG TTCAAGGCTA CAAGCCCCCG GGGAGAGCCC 
CAGGATGGAC TCTACTGCAT CCGGAACTCC TCTACCAAGT CGGGGAAGGT CCTGGTTGTG 
TGGGACGAAA CCTCTAACAA AGTGAGGAAC TATCGCATTT TTGAGAAGGA CTCTAAGTTC 
TACCTGGAGG GCGAGGTCCT GTTTGTGAGT GTGGGCAGCA TGGTGGAGCA CTACCACACC 
CACGTGCTGC CCAGCCACCA GAGCCTGCTG CTGCGGCACC CCTACGGCTA CACTGGGCCT 
AGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3BP2 ( NM_001122681.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001116153.1 Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16490
Clone ID Related Accession (Same CDS sequence)	NM_003023.4 , NM_001122681.1 , NM_001122681.2
Accession Version	NM_001122681.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	SH3 domain-binding protein 2 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK225497.1, AK312286.1 and AL121750.22. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (2) represents use of an alternative promoter and 5' UTR and uses a downstream translation start site, compared to variant 3. The resulting isoform (a) has a shorter N-terminus, compared to isoform b. Both variants 1 and 2 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC022996.1, AK225497.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTG AAGAGATGCA TTGGCCTGTC CCTATGAAGG CCATTGGTGC CCAGAACCTG 
CTAACCATGC CTGGGGGCGT GGCCAAGGCT GGCTACCTGC ACAAGAAGGG CGGTACCCAG 
CTGCAGCTGC TGAAATGGCC CCTGCGCTTT GTCATCATCC ACAAACGCTG CGTCTACTAC 
TTCAAGAGTA GCACCTCTGC CTCCCCGCAG GGCGCCTTCT CCCTGAGTGG CTATAACCGG 
GTGATGCGGG CGGCTGAGGA GACCACGTCC AACAACGTTT TCCCCTTCAA GATCATCCAT 
ATCAGCAAGA AGCACCGCAC GTGGTTCTTC TCGGCCTCCT CCGAGGAGGA GCGCAAGAGC 
TGGATGGCCT TGCTGCGCAG GGAGATTGGC CACTTCCACG AAAAGAAAGA CCTGCCCTTG 
GACACCAGCG ACTCCAGCTC GGACACAGAC AGCTTCTACG GCGCAGTTGA GCGGCCTGTG 
GATATCAGCC TTTCCCCGTA CCCCACGGAC AATGAAGACT ATGAGCACGA CGATGAGGAT 
GACTCCTACC TGGAGCCTGA CTCCCCGGAG CCCGGAAGGC TTGAGGATGC CCTGATGCAC 
CCACCGGCTT ACCCACCACC CCCAGTGCCC ACGCCCAGGA AGCCAGCCTT CTCTGACATG 
CCCCGGGCCC ACTCCTTTAC CTCCAAGGGC CCCGGTCCCC TACTGCCACC CCCGCCCCCT 
AAGCACGGCC TCCCAGATGT TGGCCTGGCT GCTGAGGACT CCAAGAGGGA CCCACTGTGC 
CCGAGGCGGG CTGAGCCTTG CCCCAGGGTA CCTGCTACCC CCCGAAGGAT GAGCGATCCC 
CCTCTGAGCA CCATGCCCAC CGCACCCGGC CTCCGGAAAC CCCCTTGCTT CCGGGAGAGT 
GCCAGCCCCA GCCCGGAGCC CTGGACCCCT GGCCACGGGG CCTGCTCCAC TTCCAGTGCT 
GCCATCATGG CCACTGCCAC CTCCAGAAAC TGTGACAAAC TCAAGTCCTT CCACCTGTCC 
CCCCGAGGAC CACCCACATC TGAGCCCCCA CCTGTGCCAG CCAACAAGCC CAAGTTCCTG 
AAGATAGCTG AAGAGGACCC CCCAAGGGAG GCAGCCATGC CCGGACTCTT TGTGCCCCCC 
GTGGCTCCCC GGCCTCCTGC GCTGAAGCTG CCAGTGCCTG AGGCCATGGC GCGGCCCGCA 
GTCCTGCCCA GGCCAGAGAA GCCGCAGCTC CCGCACCTCC AGCGATCACC CCCCGATGGG 
CAGAGTTTCA GGAGCTTCTC CTTTGAAAAG CCCCGGCAAC CCTCACAGGC TGACACTGGC 
GGGGACGACT CGGACGAGGA CTATGAGAAG GTGCCACTGC CCAACTCGGT CTTCGTCAAC 
ACCACGGAGT CCTGCGAAGT GGAAAGGTTG TTCAAGGCTA CAAGCCCCCG GGGAGAGCCC 
CAGGATGGAC TCTACTGCAT CCGGAACTCC TCTACCAAGT CGGGGAAGGT CCTGGTTGTG 
TGGGACGAAA CCTCTAACAA AGTGAGGAAC TATCGCATTT TTGAGAAGGA CTCTAAGTTC 
TACCTGGAGG GCGAGGTCCT GTTTGTGAGT GTGGGCAGCA TGGTGGAGCA CTACCACACC 
CACGTGCTGC CCAGCCACCA GAGCCTGCTG CTGCGGCACC CCTACGGCTA CACTGGGCCT 
AGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001116153.1
CDS	121..1806
Translation	MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR

Target ORF information:

RefSeq Version	NM_001122681.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001122681.1

ORF Insert Sequence:

ATGGCGGCTG AAGAGATGCA TTGGCCTGTC CCTATGAAGG CCATTGGTGC CCAGAACCTG 
CTAACCATGC CTGGGGGCGT GGCCAAGGCT GGCTACCTGC ACAAGAAGGG CGGTACCCAG 
CTGCAGCTGC TGAAATGGCC CCTGCGCTTT GTCATCATCC ACAAACGCTG CGTCTACTAC 
TTCAAGAGTA GCACCTCTGC CTCCCCGCAG GGCGCCTTCT CCCTGAGTGG CTATAACCGG 
GTGATGCGGG CGGCTGAGGA GACCACGTCC AACAACGTTT TCCCCTTCAA GATCATCCAT 
ATCAGCAAGA AGCACCGCAC GTGGTTCTTC TCGGCCTCCT CCGAGGAGGA GCGCAAGAGC 
TGGATGGCCT TGCTGCGCAG GGAGATTGGC CACTTCCACG AAAAGAAAGA CCTGCCCTTG 
GACACCAGCG ACTCCAGCTC GGACACAGAC AGCTTCTACG GCGCAGTTGA GCGGCCTGTG 
GATATCAGCC TTTCCCCGTA CCCCACGGAC AATGAAGACT ATGAGCACGA CGATGAGGAT 
GACTCCTACC TGGAGCCTGA CTCCCCGGAG CCCGGAAGGC TTGAGGATGC CCTGATGCAC 
CCACCGGCTT ACCCACCACC CCCAGTGCCC ACGCCCAGGA AGCCAGCCTT CTCTGACATG 
CCCCGGGCCC ACTCCTTTAC CTCCAAGGGC CCCGGTCCCC TACTGCCACC CCCGCCCCCT 
AAGCACGGCC TCCCAGATGT TGGCCTGGCT GCTGAGGACT CCAAGAGGGA CCCACTGTGC 
CCGAGGCGGG CTGAGCCTTG CCCCAGGGTA CCTGCTACCC CCCGAAGGAT GAGCGATCCC 
CCTCTGAGCA CCATGCCCAC CGCACCCGGC CTCCGGAAAC CCCCTTGCTT CCGGGAGAGT 
GCCAGCCCCA GCCCGGAGCC CTGGACCCCT GGCCACGGGG CCTGCTCCAC TTCCAGTGCT 
GCCATCATGG CCACTGCCAC CTCCAGAAAC TGTGACAAAC TCAAGTCCTT CCACCTGTCC 
CCCCGAGGAC CACCCACATC TGAGCCCCCA CCTGTGCCAG CCAACAAGCC CAAGTTCCTG 
AAGATAGCTG AAGAGGACCC CCCAAGGGAG GCAGCCATGC CCGGACTCTT TGTGCCCCCC 
GTGGCTCCCC GGCCTCCTGC GCTGAAGCTG CCAGTGCCTG AGGCCATGGC GCGGCCCGCA 
GTCCTGCCCA GGCCAGAGAA GCCGCAGCTC CCGCACCTCC AGCGATCACC CCCCGATGGG 
CAGAGTTTCA GGAGCTTCTC CTTTGAAAAG CCCCGGCAAC CCTCACAGGC TGACACTGGC 
GGGGACGACT CGGACGAGGA CTATGAGAAG GTGCCACTGC CCAACTCGGT CTTCGTCAAC 
ACCACGGAGT CCTGCGAAGT GGAAAGGTTG TTCAAGGCTA CAAGCCCCCG GGGAGAGCCC 
CAGGATGGAC TCTACTGCAT CCGGAACTCC TCTACCAAGT CGGGGAAGGT CCTGGTTGTG 
TGGGACGAAA CCTCTAACAA AGTGAGGAAC TATCGCATTT TTGAGAAGGA CTCTAAGTTC 
TACCTGGAGG GCGAGGTCCT GTTTGTGAGT GTGGGCAGCA TGGTGGAGCA CTACCACACC 
CACGTGCTGC CCAGCCACCA GAGCCTGCTG CTGCGGCACC CCTACGGCTA CACTGGGCCT 
AGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3BP2 ( NM_001122681.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001116153.1 Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16490
Clone ID Related Accession (Same CDS sequence)	NM_003023.4 , NM_001122681.1 , NM_001122681.2
Accession Version	NM_001122681.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	SH3 domain-binding protein 2 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK225497.1, AK312286.1 and AL121750.22. This sequence is a reference standard in the RefSeqGene project. On Dec 13, 2018 this sequence version replaced NM_001122681.1. Transcript Variant: This variant (2) represents use of an alternative promoter and 5' UTR and uses a downstream translation start site, compared to variant 3. The resulting isoform (a) has a shorter N-terminus, compared to isoform b. Variants 1 and 2 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK312286.1, BC022996.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000503393.8/ ENSP00000422168.3 RefSeq Select criteria :: based on manual assertion, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTG AAGAGATGCA TTGGCCTGTC CCTATGAAGG CCATTGGTGC CCAGAACCTG 
CTAACCATGC CTGGGGGCGT GGCCAAGGCT GGCTACCTGC ACAAGAAGGG CGGTACCCAG 
CTGCAGCTGC TGAAATGGCC CCTGCGCTTT GTCATCATCC ACAAACGCTG CGTCTACTAC 
TTCAAGAGTA GCACCTCTGC CTCCCCGCAG GGCGCCTTCT CCCTGAGTGG CTATAACCGG 
GTGATGCGGG CGGCTGAGGA GACCACGTCC AACAACGTTT TCCCCTTCAA GATCATCCAT 
ATCAGCAAGA AGCACCGCAC GTGGTTCTTC TCGGCCTCCT CCGAGGAGGA GCGCAAGAGC 
TGGATGGCCT TGCTGCGCAG GGAGATTGGC CACTTCCACG AAAAGAAAGA CCTGCCCTTG 
GACACCAGCG ACTCCAGCTC GGACACAGAC AGCTTCTACG GCGCAGTTGA GCGGCCTGTG 
GATATCAGCC TTTCCCCGTA CCCCACGGAC AATGAAGACT ATGAGCACGA CGATGAGGAT 
GACTCCTACC TGGAGCCTGA CTCCCCGGAG CCCGGAAGGC TTGAGGATGC CCTGATGCAC 
CCACCGGCTT ACCCACCACC CCCAGTGCCC ACGCCCAGGA AGCCAGCCTT CTCTGACATG 
CCCCGGGCCC ACTCCTTTAC CTCCAAGGGC CCCGGTCCCC TACTGCCACC CCCGCCCCCT 
AAGCACGGCC TCCCAGATGT TGGCCTGGCT GCTGAGGACT CCAAGAGGGA CCCACTGTGC 
CCGAGGCGGG CTGAGCCTTG CCCCAGGGTA CCTGCTACCC CCCGAAGGAT GAGCGATCCC 
CCTCTGAGCA CCATGCCCAC CGCACCCGGC CTCCGGAAAC CCCCTTGCTT CCGGGAGAGT 
GCCAGCCCCA GCCCGGAGCC CTGGACCCCT GGCCACGGGG CCTGCTCCAC TTCCAGTGCT 
GCCATCATGG CCACTGCCAC CTCCAGAAAC TGTGACAAAC TCAAGTCCTT CCACCTGTCC 
CCCCGAGGAC CACCCACATC TGAGCCCCCA CCTGTGCCAG CCAACAAGCC CAAGTTCCTG 
AAGATAGCTG AAGAGGACCC CCCAAGGGAG GCAGCCATGC CCGGACTCTT TGTGCCCCCC 
GTGGCTCCCC GGCCTCCTGC GCTGAAGCTG CCAGTGCCTG AGGCCATGGC GCGGCCCGCA 
GTCCTGCCCA GGCCAGAGAA GCCGCAGCTC CCGCACCTCC AGCGATCACC CCCCGATGGG 
CAGAGTTTCA GGAGCTTCTC CTTTGAAAAG CCCCGGCAAC CCTCACAGGC TGACACTGGC 
GGGGACGACT CGGACGAGGA CTATGAGAAG GTGCCACTGC CCAACTCGGT CTTCGTCAAC 
ACCACGGAGT CCTGCGAAGT GGAAAGGTTG TTCAAGGCTA CAAGCCCCCG GGGAGAGCCC 
CAGGATGGAC TCTACTGCAT CCGGAACTCC TCTACCAAGT CGGGGAAGGT CCTGGTTGTG 
TGGGACGAAA CCTCTAACAA AGTGAGGAAC TATCGCATTT TTGAGAAGGA CTCTAAGTTC 
TACCTGGAGG GCGAGGTCCT GTTTGTGAGT GTGGGCAGCA TGGTGGAGCA CTACCACACC 
CACGTGCTGC CCAGCCACCA GAGCCTGCTG CTGCGGCACC CCTACGGCTA CACTGGGCCT 
AGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001116153.1
CDS	59..1744
Translation	MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR

Target ORF information:

RefSeq Version	NM_001122681.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001122681.2

ORF Insert Sequence:

ATGGCGGCTG AAGAGATGCA TTGGCCTGTC CCTATGAAGG CCATTGGTGC CCAGAACCTG 
CTAACCATGC CTGGGGGCGT GGCCAAGGCT GGCTACCTGC ACAAGAAGGG CGGTACCCAG 
CTGCAGCTGC TGAAATGGCC CCTGCGCTTT GTCATCATCC ACAAACGCTG CGTCTACTAC 
TTCAAGAGTA GCACCTCTGC CTCCCCGCAG GGCGCCTTCT CCCTGAGTGG CTATAACCGG 
GTGATGCGGG CGGCTGAGGA GACCACGTCC AACAACGTTT TCCCCTTCAA GATCATCCAT 
ATCAGCAAGA AGCACCGCAC GTGGTTCTTC TCGGCCTCCT CCGAGGAGGA GCGCAAGAGC 
TGGATGGCCT TGCTGCGCAG GGAGATTGGC CACTTCCACG AAAAGAAAGA CCTGCCCTTG 
GACACCAGCG ACTCCAGCTC GGACACAGAC AGCTTCTACG GCGCAGTTGA GCGGCCTGTG 
GATATCAGCC TTTCCCCGTA CCCCACGGAC AATGAAGACT ATGAGCACGA CGATGAGGAT 
GACTCCTACC TGGAGCCTGA CTCCCCGGAG CCCGGAAGGC TTGAGGATGC CCTGATGCAC 
CCACCGGCTT ACCCACCACC CCCAGTGCCC ACGCCCAGGA AGCCAGCCTT CTCTGACATG 
CCCCGGGCCC ACTCCTTTAC CTCCAAGGGC CCCGGTCCCC TACTGCCACC CCCGCCCCCT 
AAGCACGGCC TCCCAGATGT TGGCCTGGCT GCTGAGGACT CCAAGAGGGA CCCACTGTGC 
CCGAGGCGGG CTGAGCCTTG CCCCAGGGTA CCTGCTACCC CCCGAAGGAT GAGCGATCCC 
CCTCTGAGCA CCATGCCCAC CGCACCCGGC CTCCGGAAAC CCCCTTGCTT CCGGGAGAGT 
GCCAGCCCCA GCCCGGAGCC CTGGACCCCT GGCCACGGGG CCTGCTCCAC TTCCAGTGCT 
GCCATCATGG CCACTGCCAC CTCCAGAAAC TGTGACAAAC TCAAGTCCTT CCACCTGTCC 
CCCCGAGGAC CACCCACATC TGAGCCCCCA CCTGTGCCAG CCAACAAGCC CAAGTTCCTG 
AAGATAGCTG AAGAGGACCC CCCAAGGGAG GCAGCCATGC CCGGACTCTT TGTGCCCCCC 
GTGGCTCCCC GGCCTCCTGC GCTGAAGCTG CCAGTGCCTG AGGCCATGGC GCGGCCCGCA 
GTCCTGCCCA GGCCAGAGAA GCCGCAGCTC CCGCACCTCC AGCGATCACC CCCCGATGGG 
CAGAGTTTCA GGAGCTTCTC CTTTGAAAAG CCCCGGCAAC CCTCACAGGC TGACACTGGC 
GGGGACGACT CGGACGAGGA CTATGAGAAG GTGCCACTGC CCAACTCGGT CTTCGTCAAC 
ACCACGGAGT CCTGCGAAGT GGAAAGGTTG TTCAAGGCTA CAAGCCCCCG GGGAGAGCCC 
CAGGATGGAC TCTACTGCAT CCGGAACTCC TCTACCAAGT CGGGGAAGGT CCTGGTTGTG 
TGGGACGAAA CCTCTAACAA AGTGAGGAAC TATCGCATTT TTGAGAAGGA CTCTAAGTTC 
TACCTGGAGG GCGAGGTCCT GTTTGTGAGT GTGGGCAGCA TGGTGGAGCA CTACCACACC 
CACGTGCTGC CCAGCCACCA GAGCCTGCTG CTGCGGCACC CCTACGGCTA CACTGGGCCT 
AGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3BP2 ( NM_001145855.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139327.1 Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu22670
Clone ID Related Accession (Same CDS sequence)	NM_001145855.1 , NM_001145855.2
Accession Version	NM_001145855.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1770bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-13
Organism	Homo sapiens(human)
Product	SH3 domain-binding protein 2 isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC391267.1, AK299996.1, AK312286.1 and AL121750.22. Transcript Variant: This variant (4) represents use of an alternative promoter and 5' UTR and uses an alternate translation start site, compared to variant 3. The resulting isoform (c) has a shorter and distinct N-terminus, compared to isoform b. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK299996.1, SRR1163655.605934.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCCC TGGGCCCCAG GACACCGGCC CCGAGCAGGT CACGAGGACG GAGGGCCATG 
TGTTGGGTCA GCACCATCAG CTTCATGGCG GCTGAAGAGA TGCATTGGCC TGTCCCTATG 
AAGGCCATTG GTGCCCAGAA CCTGCTAACC ATGCCTGGGG GCGTGGCCAA GGCTGGCTAC 
CTGCACAAGA AGGGCGGTAC CCAGCTGCAG CTGCTGAAAT GGCCCCTGCG CTTTGTCATC 
ATCCACAAAC GCTGCGTCTA CTACTTCAAG AGTAGCACCT CTGCCTCCCC GCAGGGCGCC 
TTCTCCCTGA GTGGCTATAA CCGGGTGATG CGGGCGGCTG AGGAGACCAC GTCCAACAAC 
GTTTTCCCCT TCAAGATCAT CCATATCAGC AAGAAGCACC GCACGTGGTT CTTCTCGGCC 
TCCTCCGAGG AGGAGCGCAA GAGCTGGATG GCCTTGCTGC GCAGGGAGAT TGGCCACTTC 
CACGAAAAGA AAGACCTGCC CTTGGACACC AGCGACTCCA GCTCGGACAC AGACAGCTTC 
TACGGCGCAG TTGAGCGGCC TGTGGATATC AGCCTTTCCC CGTACCCCAC GGACAATGAA 
GACTATGAGC ACGACGATGA GGATGACTCC TACCTGGAGC CTGACTCCCC GGAGCCCGGA 
AGGCTTGAGG ATGCCCTGAT GCACCCACCG GCTTACCCAC CACCCCCAGT GCCCACGCCC 
AGGAAGCCAG CCTTCTCTGA CATGCCCCGG GCCCACTCCT TTACCTCCAA GGGCCCCGGT 
CCCCTACTGC CACCCCCGCC CCCTAAGCAC GGCCTCCCAG ATGTTGGCCT GGCTGCTGAG 
GACTCCAAGA GGGACCCACT GTGCCCGAGG CGGGCTGAGC CTTGCCCCAG GGTACCTGCT 
ACCCCCCGAA GGATGAGCGA TCCCCCTCTG AGCACCATGC CCACCGCACC CGGCCTCCGG 
AAACCCCCTT GCTTCCGGGA GAGTGCCAGC CCCAGCCCGG AGCCCTGGAC CCCTGGCCAC 
GGGGCCTGCT CCACTTCCAG TGCTGCCATC ATGGCCACTG CCACCTCCAG AAACTGTGAC 
AAACTCAAGT CCTTCCACCT GTCCCCCCGA GGACCACCCA CATCTGAGCC CCCACCTGTG 
CCAGCCAACA AGCCCAAGTT CCTGAAGATA GCTGAAGAGG ACCCCCCAAG GGAGGCAGCC 
ATGCCCGGAC TCTTTGTGCC CCCCGTGGCT CCCCGGCCTC CTGCGCTGAA GCTGCCAGTG 
CCTGAGGCCA TGGCGCGGCC CGCAGTCCTG CCCAGGCCAG AGAAGCCGCA GCTCCCGCAC 
CTCCAGCGAT CACCCCCCGA TGGGCAGAGT TTCAGGAGCT TCTCCTTTGA AAAGCCCCGG 
CAACCCTCAC AGGCTGACAC TGGCGGGGAC GACTCGGACG AGGACTATGA GAAGGTGCCA 
CTGCCCAACT CGGTCTTCGT CAACACCACG GAGTCCTGCG AAGTGGAAAG GTTGTTCAAG 
GCTACAAGCC CCCGGGGAGA GCCCCAGGAT GGACTCTACT GCATCCGGAA CTCCTCTACC 
AAGTCGGGGA AGGTCCTGGT TGTGTGGGAC GAAACCTCTA ACAAAGTGAG GAACTATCGC 
ATTTTTGAGA AGGACTCTAA GTTCTACCTG GAGGGCGAGG TCCTGTTTGT GAGTGTGGGC 
AGCATGGTGG AGCACTACCA CACCCACGTG CTGCCCAGCC ACCAGAGCCT GCTGCTGCGG 
CACCCCTACG GCTACACTGG GCCTAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139327.1
CDS	180..1949
Translation	MASLGPRTPAPSRSRGRRAMCWVSTISFMAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR

Target ORF information:

RefSeq Version	NM_001145855.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145855.1

ORF Insert Sequence:

ATGGCCTCCC TGGGCCCCAG GACACCGGCC CCGAGCAGGT CACGAGGACG GAGGGCCATG 
TGTTGGGTCA GCACCATCAG CTTCATGGCG GCTGAAGAGA TGCATTGGCC TGTCCCTATG 
AAGGCCATTG GTGCCCAGAA CCTGCTAACC ATGCCTGGGG GCGTGGCCAA GGCTGGCTAC 
CTGCACAAGA AGGGCGGTAC CCAGCTGCAG CTGCTGAAAT GGCCCCTGCG CTTTGTCATC 
ATCCACAAAC GCTGCGTCTA CTACTTCAAG AGTAGCACCT CTGCCTCCCC GCAGGGCGCC 
TTCTCCCTGA GTGGCTATAA CCGGGTGATG CGGGCGGCTG AGGAGACCAC GTCCAACAAC 
GTTTTCCCCT TCAAGATCAT CCATATCAGC AAGAAGCACC GCACGTGGTT CTTCTCGGCC 
TCCTCCGAGG AGGAGCGCAA GAGCTGGATG GCCTTGCTGC GCAGGGAGAT TGGCCACTTC 
CACGAAAAGA AAGACCTGCC CTTGGACACC AGCGACTCCA GCTCGGACAC AGACAGCTTC 
TACGGCGCAG TTGAGCGGCC TGTGGATATC AGCCTTTCCC CGTACCCCAC GGACAATGAA 
GACTATGAGC ACGACGATGA GGATGACTCC TACCTGGAGC CTGACTCCCC GGAGCCCGGA 
AGGCTTGAGG ATGCCCTGAT GCACCCACCG GCTTACCCAC CACCCCCAGT GCCCACGCCC 
AGGAAGCCAG CCTTCTCTGA CATGCCCCGG GCCCACTCCT TTACCTCCAA GGGCCCCGGT 
CCCCTACTGC CACCCCCGCC CCCTAAGCAC GGCCTCCCAG ATGTTGGCCT GGCTGCTGAG 
GACTCCAAGA GGGACCCACT GTGCCCGAGG CGGGCTGAGC CTTGCCCCAG GGTACCTGCT 
ACCCCCCGAA GGATGAGCGA TCCCCCTCTG AGCACCATGC CCACCGCACC CGGCCTCCGG 
AAACCCCCTT GCTTCCGGGA GAGTGCCAGC CCCAGCCCGG AGCCCTGGAC CCCTGGCCAC 
GGGGCCTGCT CCACTTCCAG TGCTGCCATC ATGGCCACTG CCACCTCCAG AAACTGTGAC 
AAACTCAAGT CCTTCCACCT GTCCCCCCGA GGACCACCCA CATCTGAGCC CCCACCTGTG 
CCAGCCAACA AGCCCAAGTT CCTGAAGATA GCTGAAGAGG ACCCCCCAAG GGAGGCAGCC 
ATGCCCGGAC TCTTTGTGCC CCCCGTGGCT CCCCGGCCTC CTGCGCTGAA GCTGCCAGTG 
CCTGAGGCCA TGGCGCGGCC CGCAGTCCTG CCCAGGCCAG AGAAGCCGCA GCTCCCGCAC 
CTCCAGCGAT CACCCCCCGA TGGGCAGAGT TTCAGGAGCT TCTCCTTTGA AAAGCCCCGG 
CAACCCTCAC AGGCTGACAC TGGCGGGGAC GACTCGGACG AGGACTATGA GAAGGTGCCA 
CTGCCCAACT CGGTCTTCGT CAACACCACG GAGTCCTGCG AAGTGGAAAG GTTGTTCAAG 
GCTACAAGCC CCCGGGGAGA GCCCCAGGAT GGACTCTACT GCATCCGGAA CTCCTCTACC 
AAGTCGGGGA AGGTCCTGGT TGTGTGGGAC GAAACCTCTA ACAAAGTGAG GAACTATCGC 
ATTTTTGAGA AGGACTCTAA GTTCTACCTG GAGGGCGAGG TCCTGTTTGT GAGTGTGGGC 
AGCATGGTGG AGCACTACCA CACCCACGTG CTGCCCAGCC ACCAGAGCCT GCTGCTGCGG 
CACCCCTACG GCTACACTGG GCCTAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3BP2 ( NM_001145855.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139327.1 Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu22670
Clone ID Related Accession (Same CDS sequence)	NM_001145855.1 , NM_001145855.2
Accession Version	NM_001145855.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1770bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	SH3 domain-binding protein 2 isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC391267.1, AK299996.1, AK312286.1 and AL121750.22. This sequence is a reference standard in the RefSeqGene project. On Jan 15, 2019 this sequence version replaced NM_001145855.1. Transcript Variant: This variant (4) represents use of an alternative promoter and 5' UTR and uses an alternate translation start site, compared to variant 3. The resulting isoform (c) has a shorter and distinct N-terminus, compared to isoform b. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK299996.1, SRR1163655.605934.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCCC TGGGCCCCAG GACACCGGCC CCGAGCAGGT CACGAGGACG GAGGGCCATG 
TGTTGGGTCA GCACCATCAG CTTCATGGCG GCTGAAGAGA TGCATTGGCC TGTCCCTATG 
AAGGCCATTG GTGCCCAGAA CCTGCTAACC ATGCCTGGGG GCGTGGCCAA GGCTGGCTAC 
CTGCACAAGA AGGGCGGTAC CCAGCTGCAG CTGCTGAAAT GGCCCCTGCG CTTTGTCATC 
ATCCACAAAC GCTGCGTCTA CTACTTCAAG AGTAGCACCT CTGCCTCCCC GCAGGGCGCC 
TTCTCCCTGA GTGGCTATAA CCGGGTGATG CGGGCGGCTG AGGAGACCAC GTCCAACAAC 
GTTTTCCCCT TCAAGATCAT CCATATCAGC AAGAAGCACC GCACGTGGTT CTTCTCGGCC 
TCCTCCGAGG AGGAGCGCAA GAGCTGGATG GCCTTGCTGC GCAGGGAGAT TGGCCACTTC 
CACGAAAAGA AAGACCTGCC CTTGGACACC AGCGACTCCA GCTCGGACAC AGACAGCTTC 
TACGGCGCAG TTGAGCGGCC TGTGGATATC AGCCTTTCCC CGTACCCCAC GGACAATGAA 
GACTATGAGC ACGACGATGA GGATGACTCC TACCTGGAGC CTGACTCCCC GGAGCCCGGA 
AGGCTTGAGG ATGCCCTGAT GCACCCACCG GCTTACCCAC CACCCCCAGT GCCCACGCCC 
AGGAAGCCAG CCTTCTCTGA CATGCCCCGG GCCCACTCCT TTACCTCCAA GGGCCCCGGT 
CCCCTACTGC CACCCCCGCC CCCTAAGCAC GGCCTCCCAG ATGTTGGCCT GGCTGCTGAG 
GACTCCAAGA GGGACCCACT GTGCCCGAGG CGGGCTGAGC CTTGCCCCAG GGTACCTGCT 
ACCCCCCGAA GGATGAGCGA TCCCCCTCTG AGCACCATGC CCACCGCACC CGGCCTCCGG 
AAACCCCCTT GCTTCCGGGA GAGTGCCAGC CCCAGCCCGG AGCCCTGGAC CCCTGGCCAC 
GGGGCCTGCT CCACTTCCAG TGCTGCCATC ATGGCCACTG CCACCTCCAG AAACTGTGAC 
AAACTCAAGT CCTTCCACCT GTCCCCCCGA GGACCACCCA CATCTGAGCC CCCACCTGTG 
CCAGCCAACA AGCCCAAGTT CCTGAAGATA GCTGAAGAGG ACCCCCCAAG GGAGGCAGCC 
ATGCCCGGAC TCTTTGTGCC CCCCGTGGCT CCCCGGCCTC CTGCGCTGAA GCTGCCAGTG 
CCTGAGGCCA TGGCGCGGCC CGCAGTCCTG CCCAGGCCAG AGAAGCCGCA GCTCCCGCAC 
CTCCAGCGAT CACCCCCCGA TGGGCAGAGT TTCAGGAGCT TCTCCTTTGA AAAGCCCCGG 
CAACCCTCAC AGGCTGACAC TGGCGGGGAC GACTCGGACG AGGACTATGA GAAGGTGCCA 
CTGCCCAACT CGGTCTTCGT CAACACCACG GAGTCCTGCG AAGTGGAAAG GTTGTTCAAG 
GCTACAAGCC CCCGGGGAGA GCCCCAGGAT GGACTCTACT GCATCCGGAA CTCCTCTACC 
AAGTCGGGGA AGGTCCTGGT TGTGTGGGAC GAAACCTCTA ACAAAGTGAG GAACTATCGC 
ATTTTTGAGA AGGACTCTAA GTTCTACCTG GAGGGCGAGG TCCTGTTTGT GAGTGTGGGC 
AGCATGGTGG AGCACTACCA CACCCACGTG CTGCCCAGCC ACCAGAGCCT GCTGCTGCGG 
CACCCCTACG GCTACACTGG GCCTAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139327.1
CDS	108..1877
Translation	MASLGPRTPAPSRSRGRRAMCWVSTISFMAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR

Target ORF information:

RefSeq Version	NM_001145855.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145855.2

ORF Insert Sequence:

ATGGCCTCCC TGGGCCCCAG GACACCGGCC CCGAGCAGGT CACGAGGACG GAGGGCCATG 
TGTTGGGTCA GCACCATCAG CTTCATGGCG GCTGAAGAGA TGCATTGGCC TGTCCCTATG 
AAGGCCATTG GTGCCCAGAA CCTGCTAACC ATGCCTGGGG GCGTGGCCAA GGCTGGCTAC 
CTGCACAAGA AGGGCGGTAC CCAGCTGCAG CTGCTGAAAT GGCCCCTGCG CTTTGTCATC 
ATCCACAAAC GCTGCGTCTA CTACTTCAAG AGTAGCACCT CTGCCTCCCC GCAGGGCGCC 
TTCTCCCTGA GTGGCTATAA CCGGGTGATG CGGGCGGCTG AGGAGACCAC GTCCAACAAC 
GTTTTCCCCT TCAAGATCAT CCATATCAGC AAGAAGCACC GCACGTGGTT CTTCTCGGCC 
TCCTCCGAGG AGGAGCGCAA GAGCTGGATG GCCTTGCTGC GCAGGGAGAT TGGCCACTTC 
CACGAAAAGA AAGACCTGCC CTTGGACACC AGCGACTCCA GCTCGGACAC AGACAGCTTC 
TACGGCGCAG TTGAGCGGCC TGTGGATATC AGCCTTTCCC CGTACCCCAC GGACAATGAA 
GACTATGAGC ACGACGATGA GGATGACTCC TACCTGGAGC CTGACTCCCC GGAGCCCGGA 
AGGCTTGAGG ATGCCCTGAT GCACCCACCG GCTTACCCAC CACCCCCAGT GCCCACGCCC 
AGGAAGCCAG CCTTCTCTGA CATGCCCCGG GCCCACTCCT TTACCTCCAA GGGCCCCGGT 
CCCCTACTGC CACCCCCGCC CCCTAAGCAC GGCCTCCCAG ATGTTGGCCT GGCTGCTGAG 
GACTCCAAGA GGGACCCACT GTGCCCGAGG CGGGCTGAGC CTTGCCCCAG GGTACCTGCT 
ACCCCCCGAA GGATGAGCGA TCCCCCTCTG AGCACCATGC CCACCGCACC CGGCCTCCGG 
AAACCCCCTT GCTTCCGGGA GAGTGCCAGC CCCAGCCCGG AGCCCTGGAC CCCTGGCCAC 
GGGGCCTGCT CCACTTCCAG TGCTGCCATC ATGGCCACTG CCACCTCCAG AAACTGTGAC 
AAACTCAAGT CCTTCCACCT GTCCCCCCGA GGACCACCCA CATCTGAGCC CCCACCTGTG 
CCAGCCAACA AGCCCAAGTT CCTGAAGATA GCTGAAGAGG ACCCCCCAAG GGAGGCAGCC 
ATGCCCGGAC TCTTTGTGCC CCCCGTGGCT CCCCGGCCTC CTGCGCTGAA GCTGCCAGTG 
CCTGAGGCCA TGGCGCGGCC CGCAGTCCTG CCCAGGCCAG AGAAGCCGCA GCTCCCGCAC 
CTCCAGCGAT CACCCCCCGA TGGGCAGAGT TTCAGGAGCT TCTCCTTTGA AAAGCCCCGG 
CAACCCTCAC AGGCTGACAC TGGCGGGGAC GACTCGGACG AGGACTATGA GAAGGTGCCA 
CTGCCCAACT CGGTCTTCGT CAACACCACG GAGTCCTGCG AAGTGGAAAG GTTGTTCAAG 
GCTACAAGCC CCCGGGGAGA GCCCCAGGAT GGACTCTACT GCATCCGGAA CTCCTCTACC 
AAGTCGGGGA AGGTCCTGGT TGTGTGGGAC GAAACCTCTA ACAAAGTGAG GAACTATCGC 
ATTTTTGAGA AGGACTCTAA GTTCTACCTG GAGGGCGAGG TCCTGTTTGT GAGTGTGGGC 
AGCATGGTGG AGCACTACCA CACCCACGTG CTGCCCAGCC ACCAGAGCCT GCTGCTGCGG 
CACCCCTACG GCTACACTGG GCCTAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3BP2 ( NM_001145856.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139328.1 Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 3, mRNA.

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CloneID	OHu23162
Clone ID Related Accession (Same CDS sequence)	NM_001145856.1 , NM_001145856.2
Accession Version	NM_001145856.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1857bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-19
Organism	Homo sapiens(human)
Product	SH3 domain-binding protein 2 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U56386.1, AL121750.22 and AK225497.1. Transcript Variant: This variant (3) encodes the longest isoform (b). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U56386.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGCT CCGGGCCGCG GCCGCGGAGC TGGGGCCGGC GGGAGGCGGG CGCCCGGGAC 
GAGGCGGCGG CGGCCGGGGG ACGCGGCCCG GGGCCGTGCC GGTGCTCGCA GGGGAGGCGG 
GCGTGGATCG CCCCGGGGAA GCCGGCCATG CCCGCCGCGT GGACGCCCTT CATGGCGGCT 
GAAGAGATGC ATTGGCCTGT CCCTATGAAG GCCATTGGTG CCCAGAACCT GCTAACCATG 
CCTGGGGGCG TGGCCAAGGC TGGCTACCTG CACAAGAAGG GCGGTACCCA GCTGCAGCTG 
CTGAAATGGC CCCTGCGCTT TGTCATCATC CACAAACGCT GCGTCTACTA CTTCAAGAGT 
AGCACCTCTG CCTCCCCGCA GGGCGCCTTC TCCCTGAGTG GCTATAACCG GGTGATGCGG 
GCGGCTGAGG AGACCACGTC CAACAACGTT TTCCCCTTCA AGATCATCCA TATCAGCAAG 
AAGCACCGCA CGTGGTTCTT CTCGGCCTCC TCCGAGGAGG AGCGCAAGAG CTGGATGGCC 
TTGCTGCGCA GGGAGATTGG CCACTTCCAC GAAAAGAAAG ACCTGCCCTT GGACACCAGC 
GACTCCAGCT CGGACACAGA CAGCTTCTAC GGCGCAGTTG AGCGGCCTGT GGATATCAGC 
CTTTCCCCGT ACCCCACGGA CAATGAAGAC TATGAGCACG ACGATGAGGA TGACTCCTAC 
CTGGAGCCTG ACTCCCCGGA GCCCGGAAGG CTTGAGGATG CCCTGATGCA CCCACCGGCT 
TACCCACCAC CCCCAGTGCC CACGCCCAGG AAGCCAGCCT TCTCTGACAT GCCCCGGGCC 
CACTCCTTTA CCTCCAAGGG CCCCGGTCCC CTACTGCCAC CCCCGCCCCC TAAGCACGGC 
CTCCCAGATG TTGGCCTGGC TGCTGAGGAC TCCAAGAGGG ACCCACTGTG CCCGAGGCGG 
GCTGAGCCTT GCCCCAGGGT ACCTGCTACC CCCCGAAGGA TGAGCGATCC CCCTCTGAGC 
ACCATGCCCA CCGCACCCGG CCTCCGGAAA CCCCCTTGCT TCCGGGAGAG TGCCAGCCCC 
AGCCCGGAGC CCTGGACCCC TGGCCACGGG GCCTGCTCCA CTTCCAGTGC TGCCATCATG 
GCCACTGCCA CCTCCAGAAA CTGTGACAAA CTCAAGTCCT TCCACCTGTC CCCCCGAGGA 
CCACCCACAT CTGAGCCCCC ACCTGTGCCA GCCAACAAGC CCAAGTTCCT GAAGATAGCT 
GAAGAGGACC CCCCAAGGGA GGCAGCCATG CCCGGACTCT TTGTGCCCCC CGTGGCTCCC 
CGGCCTCCTG CGCTGAAGCT GCCAGTGCCT GAGGCCATGG CGCGGCCCGC AGTCCTGCCC 
AGGCCAGAGA AGCCGCAGCT CCCGCACCTC CAGCGATCAC CCCCCGATGG GCAGAGTTTC 
AGGAGCTTCT CCTTTGAAAA GCCCCGGCAA CCCTCACAGG CTGACACTGG CGGGGACGAC 
TCGGACGAGG ACTATGAGAA GGTGCCACTG CCCAACTCGG TCTTCGTCAA CACCACGGAG 
TCCTGCGAAG TGGAAAGGTT GTTCAAGGCT ACAAGCCCCC GGGGAGAGCC CCAGGATGGA 
CTCTACTGCA TCCGGAACTC CTCTACCAAG TCGGGGAAGG TCCTGGTTGT GTGGGACGAA 
ACCTCTAACA AAGTGAGGAA CTATCGCATT TTTGAGAAGG ACTCTAAGTT CTACCTGGAG 
GGCGAGGTCC TGTTTGTGAG TGTGGGCAGC ATGGTGGAGC ACTACCACAC CCACGTGCTG 
CCCAGCCACC AGAGCCTGCT GCTGCGGCAC CCCTACGGCT ACACTGGGCC TAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139328.1
CDS	40..1896
Translation	MAGSGPRPRSWGRREAGARDEAAAAGGRGPGPCRCSQGRRAWIAPGKPAMPAAWTPFMAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR

Target ORF information:

RefSeq Version	NM_001145856.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145856.1

ORF Insert Sequence:

ATGGCGGGCT CCGGGCCGCG GCCGCGGAGC TGGGGCCGGC GGGAGGCGGG CGCCCGGGAC 
GAGGCGGCGG CGGCCGGGGG ACGCGGCCCG GGGCCGTGCC GGTGCTCGCA GGGGAGGCGG 
GCGTGGATCG CCCCGGGGAA GCCGGCCATG CCCGCCGCGT GGACGCCCTT CATGGCGGCT 
GAAGAGATGC ATTGGCCTGT CCCTATGAAG GCCATTGGTG CCCAGAACCT GCTAACCATG 
CCTGGGGGCG TGGCCAAGGC TGGCTACCTG CACAAGAAGG GCGGTACCCA GCTGCAGCTG 
CTGAAATGGC CCCTGCGCTT TGTCATCATC CACAAACGCT GCGTCTACTA CTTCAAGAGT 
AGCACCTCTG CCTCCCCGCA GGGCGCCTTC TCCCTGAGTG GCTATAACCG GGTGATGCGG 
GCGGCTGAGG AGACCACGTC CAACAACGTT TTCCCCTTCA AGATCATCCA TATCAGCAAG 
AAGCACCGCA CGTGGTTCTT CTCGGCCTCC TCCGAGGAGG AGCGCAAGAG CTGGATGGCC 
TTGCTGCGCA GGGAGATTGG CCACTTCCAC GAAAAGAAAG ACCTGCCCTT GGACACCAGC 
GACTCCAGCT CGGACACAGA CAGCTTCTAC GGCGCAGTTG AGCGGCCTGT GGATATCAGC 
CTTTCCCCGT ACCCCACGGA CAATGAAGAC TATGAGCACG ACGATGAGGA TGACTCCTAC 
CTGGAGCCTG ACTCCCCGGA GCCCGGAAGG CTTGAGGATG CCCTGATGCA CCCACCGGCT 
TACCCACCAC CCCCAGTGCC CACGCCCAGG AAGCCAGCCT TCTCTGACAT GCCCCGGGCC 
CACTCCTTTA CCTCCAAGGG CCCCGGTCCC CTACTGCCAC CCCCGCCCCC TAAGCACGGC 
CTCCCAGATG TTGGCCTGGC TGCTGAGGAC TCCAAGAGGG ACCCACTGTG CCCGAGGCGG 
GCTGAGCCTT GCCCCAGGGT ACCTGCTACC CCCCGAAGGA TGAGCGATCC CCCTCTGAGC 
ACCATGCCCA CCGCACCCGG CCTCCGGAAA CCCCCTTGCT TCCGGGAGAG TGCCAGCCCC 
AGCCCGGAGC CCTGGACCCC TGGCCACGGG GCCTGCTCCA CTTCCAGTGC TGCCATCATG 
GCCACTGCCA CCTCCAGAAA CTGTGACAAA CTCAAGTCCT TCCACCTGTC CCCCCGAGGA 
CCACCCACAT CTGAGCCCCC ACCTGTGCCA GCCAACAAGC CCAAGTTCCT GAAGATAGCT 
GAAGAGGACC CCCCAAGGGA GGCAGCCATG CCCGGACTCT TTGTGCCCCC CGTGGCTCCC 
CGGCCTCCTG CGCTGAAGCT GCCAGTGCCT GAGGCCATGG CGCGGCCCGC AGTCCTGCCC 
AGGCCAGAGA AGCCGCAGCT CCCGCACCTC CAGCGATCAC CCCCCGATGG GCAGAGTTTC 
AGGAGCTTCT CCTTTGAAAA GCCCCGGCAA CCCTCACAGG CTGACACTGG CGGGGACGAC 
TCGGACGAGG ACTATGAGAA GGTGCCACTG CCCAACTCGG TCTTCGTCAA CACCACGGAG 
TCCTGCGAAG TGGAAAGGTT GTTCAAGGCT ACAAGCCCCC GGGGAGAGCC CCAGGATGGA 
CTCTACTGCA TCCGGAACTC CTCTACCAAG TCGGGGAAGG TCCTGGTTGT GTGGGACGAA 
ACCTCTAACA AAGTGAGGAA CTATCGCATT TTTGAGAAGG ACTCTAAGTT CTACCTGGAG 
GGCGAGGTCC TGTTTGTGAG TGTGGGCAGC ATGGTGGAGC ACTACCACAC CCACGTGCTG 
CCCAGCCACC AGAGCCTGCT GCTGCGGCAC CCCTACGGCT ACACTGGGCC TAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3BP2 ( NM_001145856.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139328.1 Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu23162
Clone ID Related Accession (Same CDS sequence)	NM_001145856.1 , NM_001145856.2
Accession Version	NM_001145856.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1857bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	SH3 domain-binding protein 2 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL121750.22, U56386.1 and AK225497.1. On Jun 1, 2019 this sequence version replaced NM_001145856.1. Transcript Variant: This variant (3) encodes the longest isoform (b). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U56386.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGCT CCGGGCCGCG GCCGCGGAGC TGGGGCCGGC GGGAGGCGGG CGCCCGGGAC 
GAGGCGGCGG CGGCCGGGGG ACGCGGCCCG GGGCCGTGCC GGTGCTCGCA GGGGAGGCGG 
GCGTGGATCG CCCCGGGGAA GCCGGCCATG CCCGCCGCGT GGACGCCCTT CATGGCGGCT 
GAAGAGATGC ATTGGCCTGT CCCTATGAAG GCCATTGGTG CCCAGAACCT GCTAACCATG 
CCTGGGGGCG TGGCCAAGGC TGGCTACCTG CACAAGAAGG GCGGTACCCA GCTGCAGCTG 
CTGAAATGGC CCCTGCGCTT TGTCATCATC CACAAACGCT GCGTCTACTA CTTCAAGAGT 
AGCACCTCTG CCTCCCCGCA GGGCGCCTTC TCCCTGAGTG GCTATAACCG GGTGATGCGG 
GCGGCTGAGG AGACCACGTC CAACAACGTT TTCCCCTTCA AGATCATCCA TATCAGCAAG 
AAGCACCGCA CGTGGTTCTT CTCGGCCTCC TCCGAGGAGG AGCGCAAGAG CTGGATGGCC 
TTGCTGCGCA GGGAGATTGG CCACTTCCAC GAAAAGAAAG ACCTGCCCTT GGACACCAGC 
GACTCCAGCT CGGACACAGA CAGCTTCTAC GGCGCAGTTG AGCGGCCTGT GGATATCAGC 
CTTTCCCCGT ACCCCACGGA CAATGAAGAC TATGAGCACG ACGATGAGGA TGACTCCTAC 
CTGGAGCCTG ACTCCCCGGA GCCCGGAAGG CTTGAGGATG CCCTGATGCA CCCACCGGCT 
TACCCACCAC CCCCAGTGCC CACGCCCAGG AAGCCAGCCT TCTCTGACAT GCCCCGGGCC 
CACTCCTTTA CCTCCAAGGG CCCCGGTCCC CTACTGCCAC CCCCGCCCCC TAAGCACGGC 
CTCCCAGATG TTGGCCTGGC TGCTGAGGAC TCCAAGAGGG ACCCACTGTG CCCGAGGCGG 
GCTGAGCCTT GCCCCAGGGT ACCTGCTACC CCCCGAAGGA TGAGCGATCC CCCTCTGAGC 
ACCATGCCCA CCGCACCCGG CCTCCGGAAA CCCCCTTGCT TCCGGGAGAG TGCCAGCCCC 
AGCCCGGAGC CCTGGACCCC TGGCCACGGG GCCTGCTCCA CTTCCAGTGC TGCCATCATG 
GCCACTGCCA CCTCCAGAAA CTGTGACAAA CTCAAGTCCT TCCACCTGTC CCCCCGAGGA 
CCACCCACAT CTGAGCCCCC ACCTGTGCCA GCCAACAAGC CCAAGTTCCT GAAGATAGCT 
GAAGAGGACC CCCCAAGGGA GGCAGCCATG CCCGGACTCT TTGTGCCCCC CGTGGCTCCC 
CGGCCTCCTG CGCTGAAGCT GCCAGTGCCT GAGGCCATGG CGCGGCCCGC AGTCCTGCCC 
AGGCCAGAGA AGCCGCAGCT CCCGCACCTC CAGCGATCAC CCCCCGATGG GCAGAGTTTC 
AGGAGCTTCT CCTTTGAAAA GCCCCGGCAA CCCTCACAGG CTGACACTGG CGGGGACGAC 
TCGGACGAGG ACTATGAGAA GGTGCCACTG CCCAACTCGG TCTTCGTCAA CACCACGGAG 
TCCTGCGAAG TGGAAAGGTT GTTCAAGGCT ACAAGCCCCC GGGGAGAGCC CCAGGATGGA 
CTCTACTGCA TCCGGAACTC CTCTACCAAG TCGGGGAAGG TCCTGGTTGT GTGGGACGAA 
ACCTCTAACA AAGTGAGGAA CTATCGCATT TTTGAGAAGG ACTCTAAGTT CTACCTGGAG 
GGCGAGGTCC TGTTTGTGAG TGTGGGCAGC ATGGTGGAGC ACTACCACAC CCACGTGCTG 
CCCAGCCACC AGAGCCTGCT GCTGCGGCAC CCCTACGGCT ACACTGGGCC TAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139328.1
CDS	55..1911
Translation	MAGSGPRPRSWGRREAGARDEAAAAGGRGPGPCRCSQGRRAWIAPGKPAMPAAWTPFMAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR

Target ORF information:

RefSeq Version	NM_001145856.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain binding protein 2 (SH3BP2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145856.2

ORF Insert Sequence:

ATGGCGGGCT CCGGGCCGCG GCCGCGGAGC TGGGGCCGGC GGGAGGCGGG CGCCCGGGAC 
GAGGCGGCGG CGGCCGGGGG ACGCGGCCCG GGGCCGTGCC GGTGCTCGCA GGGGAGGCGG 
GCGTGGATCG CCCCGGGGAA GCCGGCCATG CCCGCCGCGT GGACGCCCTT CATGGCGGCT 
GAAGAGATGC ATTGGCCTGT CCCTATGAAG GCCATTGGTG CCCAGAACCT GCTAACCATG 
CCTGGGGGCG TGGCCAAGGC TGGCTACCTG CACAAGAAGG GCGGTACCCA GCTGCAGCTG 
CTGAAATGGC CCCTGCGCTT TGTCATCATC CACAAACGCT GCGTCTACTA CTTCAAGAGT 
AGCACCTCTG CCTCCCCGCA GGGCGCCTTC TCCCTGAGTG GCTATAACCG GGTGATGCGG 
GCGGCTGAGG AGACCACGTC CAACAACGTT TTCCCCTTCA AGATCATCCA TATCAGCAAG 
AAGCACCGCA CGTGGTTCTT CTCGGCCTCC TCCGAGGAGG AGCGCAAGAG CTGGATGGCC 
TTGCTGCGCA GGGAGATTGG CCACTTCCAC GAAAAGAAAG ACCTGCCCTT GGACACCAGC 
GACTCCAGCT CGGACACAGA CAGCTTCTAC GGCGCAGTTG AGCGGCCTGT GGATATCAGC 
CTTTCCCCGT ACCCCACGGA CAATGAAGAC TATGAGCACG ACGATGAGGA TGACTCCTAC 
CTGGAGCCTG ACTCCCCGGA GCCCGGAAGG CTTGAGGATG CCCTGATGCA CCCACCGGCT 
TACCCACCAC CCCCAGTGCC CACGCCCAGG AAGCCAGCCT TCTCTGACAT GCCCCGGGCC 
CACTCCTTTA CCTCCAAGGG CCCCGGTCCC CTACTGCCAC CCCCGCCCCC TAAGCACGGC 
CTCCCAGATG TTGGCCTGGC TGCTGAGGAC TCCAAGAGGG ACCCACTGTG CCCGAGGCGG 
GCTGAGCCTT GCCCCAGGGT ACCTGCTACC CCCCGAAGGA TGAGCGATCC CCCTCTGAGC 
ACCATGCCCA CCGCACCCGG CCTCCGGAAA CCCCCTTGCT TCCGGGAGAG TGCCAGCCCC 
AGCCCGGAGC CCTGGACCCC TGGCCACGGG GCCTGCTCCA CTTCCAGTGC TGCCATCATG 
GCCACTGCCA CCTCCAGAAA CTGTGACAAA CTCAAGTCCT TCCACCTGTC CCCCCGAGGA 
CCACCCACAT CTGAGCCCCC ACCTGTGCCA GCCAACAAGC CCAAGTTCCT GAAGATAGCT 
GAAGAGGACC CCCCAAGGGA GGCAGCCATG CCCGGACTCT TTGTGCCCCC CGTGGCTCCC 
CGGCCTCCTG CGCTGAAGCT GCCAGTGCCT GAGGCCATGG CGCGGCCCGC AGTCCTGCCC 
AGGCCAGAGA AGCCGCAGCT CCCGCACCTC CAGCGATCAC CCCCCGATGG GCAGAGTTTC 
AGGAGCTTCT CCTTTGAAAA GCCCCGGCAA CCCTCACAGG CTGACACTGG CGGGGACGAC 
TCGGACGAGG ACTATGAGAA GGTGCCACTG CCCAACTCGG TCTTCGTCAA CACCACGGAG 
TCCTGCGAAG TGGAAAGGTT GTTCAAGGCT ACAAGCCCCC GGGGAGAGCC CCAGGATGGA 
CTCTACTGCA TCCGGAACTC CTCTACCAAG TCGGGGAAGG TCCTGGTTGT GTGGGACGAA 
ACCTCTAACA AAGTGAGGAA CTATCGCATT TTTGAGAAGG ACTCTAAGTT CTACCTGGAG 
GGCGAGGTCC TGTTTGTGAG TGTGGGCAGC ATGGTGGAGC ACTACCACAC CCACGTGCTG 
CCCAGCCACC AGAGCCTGCT GCTGCGGCAC CCCTACGGCT ACACTGGGCC TAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Clinicopathologic and Molecular Characteristics of Familial Cherubism with Associated Odontogenic Tumorous Proliferations.
Head and neck pathology(2017 Jul)
Argyris PP,Gopalakrishnan R,Hu Y,Reichenberger EJ,Koutlas IG

The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival.
Journal of immunology (Baltimore, Md. : 1950)194(9)4309-18(2015 May)
Ainsua-Enrich E,Serrano-Candelas E,?lvarez-Errico D,Picado C,Say?s J,Rivera J,Mart?n M

A c.1244G>A (p.Arg415Gln) mutation in SH3BP2 gene causes cherubism in a Turkish family: report of a family with review of the literature.
Medicina oral, patologia oral y cirugia bucal19(4)e340-4(2014 Jul)
Sekerci AE,Balta B,Dundar M,Hu Y,Reichenberger EJ,Etoz OA,Nazlim S,Bayrakdar IS

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.
Molecular & cellular proteomics : MCP13(7)1705-23(2014 Jul)
Leung KK,Hause RJ Jr,Barkinge JL,Ciaccio MF,Chuu CP,Jones RB

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SH3BP2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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