Gene Symbol | NLGN4X |
Entrez Gene ID | 57502 |
Full Name | neuroligin 4, X-linked |
Synonyms | ASPGX2,AUTSX2,HLNX,HNL4X,NLGN4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]. |
Disorder MIM: | |
Disorder Html: | {Autism susceptibility, X-linked 2}, 300495 (3); {Asperger syndrome susceptibility, X-linked 2}, 300497 (3); Mental retardation, X-linked, 300495 (3) |