BACE1 cDNA ORF clone, Homo sapiens(human)

The following BACE1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BACE1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu18886 NM_012104.4
Latest version!
Homo sapiens beta-secretase 1 (BACE1), transcript variant a, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$219.50-$307.30
$439.00
OHu19699 NM_138973.3
Latest version!
Homo sapiens beta-secretase 1 (BACE1), transcript variant d, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$179.50-$251.30
$359.00
OHu18091 NM_001207048.2
Latest version!
Homo sapiens beta-secretase 1 (BACE1), transcript variant e, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu18219 NM_001207049.2
Latest version!
Homo sapiens beta-secretase 1 (BACE1), transcript variant f, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu17837 NM_138971.3
Latest version!
Homo sapiens beta-secretase 1 (BACE1), transcript variant c, mRNA. pcDNA3.1-C-(k)DYK or customized vector TBD $272.30
$389.00
OHu18478 NM_138972.3
Latest version!
Homo sapiens beta-secretase 1 (BACE1), transcript variant b, mRNA. pcDNA3.1-C-(k)DYK or customized vector TBD $286.30
$409.00
View Old Accession Versions >>
OHu18219 NM_001207049.1 Homo sapiens beta-secretase 1 (BACE1), transcript variant f, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu18091 NM_001207048.1 Homo sapiens beta-secretase 1 (BACE1), transcript variant e, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu18886
    Clone ID Related Accession (Same CDS sequence) NM_012104.4
    Accession Version NM_012104.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1506bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-27
    Organism Homo sapiens(human)
    Product beta-secretase 1 isoform A preproprotein
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC065492.1, AB032975.2 and BM996673.1. This sequence is a reference standard in the RefSeqGene project. On May 19, 2011 this sequence version replaced NM_012104.3. Transcript Variant: This variant (a) is the longest transcript and it encodes the longest isoform (A). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065492.1, AF201468.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein regulatory uORF :: PMID: 15034149 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGGCCCAAG CCCTGCCCTG GCTCCTGCTG TGGATGGGCG CGGGAGTGCT GCCTGCCCAC 
    GGCACCCAGC ACGGCATCCG GCTGCCCCTG CGCAGCGGCC TGGGGGGCGC CCCCCTGGGG
    CTGCGGCTGC CCCGGGAGAC CGACGAAGAG CCCGAGGAGC CCGGCCGGAG GGGCAGCTTT
    GTGGAGATGG TGGACAACCT GAGGGGCAAG TCGGGGCAGG GCTACTACGT GGAGATGACC
    GTGGGCAGCC CCCCGCAGAC GCTCAACATC CTGGTGGATA CAGGCAGCAG TAACTTTGCA
    GTGGGTGCTG CCCCCCACCC CTTCCTGCAT CGCTACTACC AGAGGCAGCT GTCCAGCACA
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGGTAAG CATCCCCCAT GGCCCCAACG TCACTGTGCG TGCCAACATT
    GCTGCCATCA CTGAATCAGA CAAGTTCTTC ATCAACGGCT CCAACTGGGA AGGCATCCTG
    GGGCTGGCCT ATGCTGAGAT TGCCAGGCCT GACGACTCCC TGGAGCCTTT CTTTGACTCT
    CTGGTAAAGC AGACCCACGT TCCCAACCTC TTCTCCCTGC AGCTTTGTGG TGCTGGCTTC
    CCCCTCAACC AGTCTGAAGT GCTGGCCTCT GTCGGAGGGA GCATGATCAT TGGAGGTATC
    GACCACTCGC TGTACACAGG CAGTCTCTGG TATACACCCA TCCGGCGGGA GTGGTATTAT
    GAGGTGATCA TTGTGCGGGT GGAGATCAAT GGACAGGATC TGAAAATGGA CTGCAAGGAG
    TACAACTATG ACAAGAGCAT TGTGGACAGT GGCACCACCA ACCTTCGTTT GCCCAAGAAA
    GTGTTTGAAG CTGCAGTCAA ATCCATCAAG GCAGCCTCCT CCACGGAGAA GTTCCCTGAT
    GGTTTCTGGC TAGGAGAGCA GCTGGTGTGC TGGCAAGCAG GCACCACCCC TTGGAACATT
    TTCCCAGTCA TCTCACTCTA CCTAATGGGT GAGGTTACCA ACCAGTCCTT CCGCATCACC
    ATCCTTCCGC AGCAATACCT GCGGCCAGTG GAAGATGTGG CCACGTCCCA AGACGACTGT
    TACAAGTTTG CCATCTCACA GTCATCCACG GGCACTGTTA TGGGAGCTGT TATCATGGAG
    GGCTTCTACG TTGTCTTTGA TCGGGCCCGA AAACGAATTG GCTTTGCTGT CAGCGCTTGC
    CATGTGCACG ATGAGTTCAG GACGGCAGCG GTGGAAGGCC CTTTTGTCAC CTTGGACATG
    GAAGACTGTG GCTACAACAT TCCACAGACA GATGAGTCAA CCCTCATGAC CATAGCCTAT
    GTCATGGCTG CCATCTGCGC CCTCTTCATG CTGCCACTCT GCCTCATGGT GTGTCAGTGG
    CGCTGCCTCC GCTGCCTGCG CCAGCAGCAT GATGACTTTG CTGATGACAT CTCCCTGCTG
    AAGTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_036236.1
    CDS462..1967
    Translation

    Target ORF information:

    RefSeq Version NM_012104.4
    Organism Homo sapiens(human)
    Definition Homo sapiens beta-secretase 1 (BACE1), transcript variant a, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_012104.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGGCCCAAG CCCTGCCCTG GCTCCTGCTG TGGATGGGCG CGGGAGTGCT GCCTGCCCAC 
    GGCACCCAGC ACGGCATCCG GCTGCCCCTG CGCAGCGGCC TGGGGGGCGC CCCCCTGGGG
    CTGCGGCTGC CCCGGGAGAC CGACGAAGAG CCCGAGGAGC CCGGCCGGAG GGGCAGCTTT
    GTGGAGATGG TGGACAACCT GAGGGGCAAG TCGGGGCAGG GCTACTACGT GGAGATGACC
    GTGGGCAGCC CCCCGCAGAC GCTCAACATC CTGGTGGATA CAGGCAGCAG TAACTTTGCA
    GTGGGTGCTG CCCCCCACCC CTTCCTGCAT CGCTACTACC AGAGGCAGCT GTCCAGCACA
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGGTAAG CATCCCCCAT GGCCCCAACG TCACTGTGCG TGCCAACATT
    GCTGCCATCA CTGAATCAGA CAAGTTCTTC ATCAACGGCT CCAACTGGGA AGGCATCCTG
    GGGCTGGCCT ATGCTGAGAT TGCCAGGCCT GACGACTCCC TGGAGCCTTT CTTTGACTCT
    CTGGTAAAGC AGACCCACGT TCCCAACCTC TTCTCCCTGC AGCTTTGTGG TGCTGGCTTC
    CCCCTCAACC AGTCTGAAGT GCTGGCCTCT GTCGGAGGGA GCATGATCAT TGGAGGTATC
    GACCACTCGC TGTACACAGG CAGTCTCTGG TATACACCCA TCCGGCGGGA GTGGTATTAT
    GAGGTGATCA TTGTGCGGGT GGAGATCAAT GGACAGGATC TGAAAATGGA CTGCAAGGAG
    TACAACTATG ACAAGAGCAT TGTGGACAGT GGCACCACCA ACCTTCGTTT GCCCAAGAAA
    GTGTTTGAAG CTGCAGTCAA ATCCATCAAG GCAGCCTCCT CCACGGAGAA GTTCCCTGAT
    GGTTTCTGGC TAGGAGAGCA GCTGGTGTGC TGGCAAGCAG GCACCACCCC TTGGAACATT
    TTCCCAGTCA TCTCACTCTA CCTAATGGGT GAGGTTACCA ACCAGTCCTT CCGCATCACC
    ATCCTTCCGC AGCAATACCT GCGGCCAGTG GAAGATGTGG CCACGTCCCA AGACGACTGT
    TACAAGTTTG CCATCTCACA GTCATCCACG GGCACTGTTA TGGGAGCTGT TATCATGGAG
    GGCTTCTACG TTGTCTTTGA TCGGGCCCGA AAACGAATTG GCTTTGCTGT CAGCGCTTGC
    CATGTGCACG ATGAGTTCAG GACGGCAGCG GTGGAAGGCC CTTTTGTCAC CTTGGACATG
    GAAGACTGTG GCTACAACAT TCCACAGACA GATGAGTCAA CCCTCATGAC CATAGCCTAT
    GTCATGGCTG CCATCTGCGC CCTCTTCATG CTGCCACTCT GCCTCATGGT GTGTCAGTGG
    CGCTGCCTCC GCTGCCTGCG CCAGCAGCAT GATGACTTTG CTGATGACAT CTCCCTGCTG
    AAGTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu19699
    Clone ID Related Accession (Same CDS sequence) NM_138973.3
    Accession Version NM_138973.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1299bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-24
    Organism Homo sapiens(human)
    Product beta-secretase 1 isoform D precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC065492.1, AB032975.2 and BM996673.1. On May 19, 2011 this sequence version replaced NM_138973.2. Transcript Variant: This variant (d) has an alternate splice junction in the coding region, compared to variant a. The resulting isoform (D) lacks an internal segment, compared to isoform A. This isoform (D) may undergo proteolytic processing similar to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB050438.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 15034149 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGGCCCAAG CCCTGCCCTG GCTCCTGCTG TGGATGGGCG CGGGAGTGCT GCCTGCCCAC 
    GGCACCCAGC ACGGCATCCG GCTGCCCCTG CGCAGCGGCC TGGGGGGCGC CCCCCTGGGG
    CTGCGGCTGC CCCGGGAGAC CGACGAAGAG CCCGAGGAGC CCGGCCGGAG GGGCAGCTTT
    GTGGAGATGG TGGACAACCT GAGGGGCAAG TCGGGGCAGG GCTACTACGT GGAGATGACC
    GTGGGCAGCC CCCCGCAGAC GCTCAACATC CTGGTGGATA CAGGCAGCAG TAACTTTGCA
    GTGGGTGCTG CCCCCCACCC CTTCCTGCAT CGCTACTACC AGAGGCAGCT GTCCAGCACA
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGCTTTG TGGTGCTGGC TTCCCCCTCA ACCAGTCTGA AGTGCTGGCC
    TCTGTCGGAG GGAGCATGAT CATTGGAGGT ATCGACCACT CGCTGTACAC AGGCAGTCTC
    TGGTATACAC CCATCCGGCG GGAGTGGTAT TATGAGGTGA TCATTGTGCG GGTGGAGATC
    AATGGACAGG ATCTGAAAAT GGACTGCAAG GAGTACAACT ATGACAAGAG CATTGTGGAC
    AGTGGCACCA CCAACCTTCG TTTGCCCAAG AAAGTGTTTG AAGCTGCAGT CAAATCCATC
    AAGGCAGCCT CCTCCACGGA GAAGTTCCCT GATGGTTTCT GGCTAGGAGA GCAGCTGGTG
    TGCTGGCAAG CAGGCACCAC CCCTTGGAAC ATTTTCCCAG TCATCTCACT CTACCTAATG
    GGTGAGGTTA CCAACCAGTC CTTCCGCATC ACCATCCTTC CGCAGCAATA CCTGCGGCCA
    GTGGAAGATG TGGCCACGTC CCAAGACGAC TGTTACAAGT TTGCCATCTC ACAGTCATCC
    ACGGGCACTG TTATGGGAGC TGTTATCATG GAGGGCTTCT ACGTTGTCTT TGATCGGGCC
    CGAAAACGAA TTGGCTTTGC TGTCAGCGCT TGCCATGTGC ACGATGAGTT CAGGACGGCA
    GCGGTGGAAG GCCCTTTTGT CACCTTGGAC ATGGAAGACT GTGGCTACAA CATTCCACAG
    ACAGATGAGT CAACCCTCAT GACCATAGCC TATGTCATGG CTGCCATCTG CGCCCTCTTC
    ATGCTGCCAC TCTGCCTCAT GGTGTGTCAG TGGCGCTGCC TCCGCTGCCT GCGCCAGCAG
    CATGATGACT TTGCTGATGA CATCTCCCTG CTGAAGTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_620429.1
    CDS462..1760
    Translation

    Target ORF information:

    RefSeq Version NM_138973.3
    Organism Homo sapiens(human)
    Definition Homo sapiens beta-secretase 1 (BACE1), transcript variant d, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_138973.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGGCCCAAG CCCTGCCCTG GCTCCTGCTG TGGATGGGCG CGGGAGTGCT GCCTGCCCAC 
    GGCACCCAGC ACGGCATCCG GCTGCCCCTG CGCAGCGGCC TGGGGGGCGC CCCCCTGGGG
    CTGCGGCTGC CCCGGGAGAC CGACGAAGAG CCCGAGGAGC CCGGCCGGAG GGGCAGCTTT
    GTGGAGATGG TGGACAACCT GAGGGGCAAG TCGGGGCAGG GCTACTACGT GGAGATGACC
    GTGGGCAGCC CCCCGCAGAC GCTCAACATC CTGGTGGATA CAGGCAGCAG TAACTTTGCA
    GTGGGTGCTG CCCCCCACCC CTTCCTGCAT CGCTACTACC AGAGGCAGCT GTCCAGCACA
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGCTTTG TGGTGCTGGC TTCCCCCTCA ACCAGTCTGA AGTGCTGGCC
    TCTGTCGGAG GGAGCATGAT CATTGGAGGT ATCGACCACT CGCTGTACAC AGGCAGTCTC
    TGGTATACAC CCATCCGGCG GGAGTGGTAT TATGAGGTGA TCATTGTGCG GGTGGAGATC
    AATGGACAGG ATCTGAAAAT GGACTGCAAG GAGTACAACT ATGACAAGAG CATTGTGGAC
    AGTGGCACCA CCAACCTTCG TTTGCCCAAG AAAGTGTTTG AAGCTGCAGT CAAATCCATC
    AAGGCAGCCT CCTCCACGGA GAAGTTCCCT GATGGTTTCT GGCTAGGAGA GCAGCTGGTG
    TGCTGGCAAG CAGGCACCAC CCCTTGGAAC ATTTTCCCAG TCATCTCACT CTACCTAATG
    GGTGAGGTTA CCAACCAGTC CTTCCGCATC ACCATCCTTC CGCAGCAATA CCTGCGGCCA
    GTGGAAGATG TGGCCACGTC CCAAGACGAC TGTTACAAGT TTGCCATCTC ACAGTCATCC
    ACGGGCACTG TTATGGGAGC TGTTATCATG GAGGGCTTCT ACGTTGTCTT TGATCGGGCC
    CGAAAACGAA TTGGCTTTGC TGTCAGCGCT TGCCATGTGC ACGATGAGTT CAGGACGGCA
    GCGGTGGAAG GCCCTTTTGT CACCTTGGAC ATGGAAGACT GTGGCTACAA CATTCCACAG
    ACAGATGAGT CAACCCTCAT GACCATAGCC TATGTCATGG CTGCCATCTG CGCCCTCTTC
    ATGCTGCCAC TCTGCCTCAT GGTGTGTCAG TGGCGCTGCC TCCGCTGCCT GCGCCAGCAG
    CATGATGACT TTGCTGATGA CATCTCCCTG CTGAAGTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu18091
    Clone ID Related Accession (Same CDS sequence) NM_001207048.2 , NM_001207048.1
    Accession Version NM_001207048.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1206bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2020-01-03
    Organism Homo sapiens(human)
    Product beta-secretase 1 isoform E
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP000892.4 and KC877486.1. On Jun 2, 2019 this sequence version replaced NM_001207048.1. Transcript Variant: This variant (e) lacks two exons from the 5' end and has an alternate 5' exon, compared to variant a. The resulting isoform (E) has a shorter and distinct N-terminus, and lacks a predicted signal peptide compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.139806.1, AB177847.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGTTCCCT TCATCTATCT GCAAGCCCAC TTTACACTCT GTTCTGGGTG GTCCAGCACA 
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGGTAAG CATCCCCCAT GGCCCCAACG TCACTGTGCG TGCCAACATT
    GCTGCCATCA CTGAATCAGA CAAGTTCTTC ATCAACGGCT CCAACTGGGA AGGCATCCTG
    GGGCTGGCCT ATGCTGAGAT TGCCAGGCCT GACGACTCCC TGGAGCCTTT CTTTGACTCT
    CTGGTAAAGC AGACCCACGT TCCCAACCTC TTCTCCCTGC AGCTTTGTGG TGCTGGCTTC
    CCCCTCAACC AGTCTGAAGT GCTGGCCTCT GTCGGAGGGA GCATGATCAT TGGAGGTATC
    GACCACTCGC TGTACACAGG CAGTCTCTGG TATACACCCA TCCGGCGGGA GTGGTATTAT
    GAGGTGATCA TTGTGCGGGT GGAGATCAAT GGACAGGATC TGAAAATGGA CTGCAAGGAG
    TACAACTATG ACAAGAGCAT TGTGGACAGT GGCACCACCA ACCTTCGTTT GCCCAAGAAA
    GTGTTTGAAG CTGCAGTCAA ATCCATCAAG GCAGCCTCCT CCACGGAGAA GTTCCCTGAT
    GGTTTCTGGC TAGGAGAGCA GCTGGTGTGC TGGCAAGCAG GCACCACCCC TTGGAACATT
    TTCCCAGTCA TCTCACTCTA CCTAATGGGT GAGGTTACCA ACCAGTCCTT CCGCATCACC
    ATCCTTCCGC AGCAATACCT GCGGCCAGTG GAAGATGTGG CCACGTCCCA AGACGACTGT
    TACAAGTTTG CCATCTCACA GTCATCCACG GGCACTGTTA TGGGAGCTGT TATCATGGAG
    GGCTTCTACG TTGTCTTTGA TCGGGCCCGA AAACGAATTG GCTTTGCTGT CAGCGCTTGC
    CATGTGCACG ATGAGTTCAG GACGGCAGCG GTGGAAGGCC CTTTTGTCAC CTTGGACATG
    GAAGACTGTG GCTACAACAT TCCACAGACA GATGAGTCAA CCCTCATGAC CATAGCCTAT
    GTCATGGCTG CCATCTGCGC CCTCTTCATG CTGCCACTCT GCCTCATGGT GTGTCAGTGG
    CGCTGCCTCC GCTGCCTGCG CCAGCAGCAT GATGACTTTG CTGATGACAT CTCCCTGCTG
    AAGTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193977.1
    CDS27..1232
    Translation

    Target ORF information:

    RefSeq Version NM_001207048.2
    Organism Homo sapiens(human)
    Definition Homo sapiens beta-secretase 1 (BACE1), transcript variant e, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001207048.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGTTCCCT TCATCTATCT GCAAGCCCAC TTTACACTCT GTTCTGGGTG GTCCAGCACA 
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGGTAAG CATCCCCCAT GGCCCCAACG TCACTGTGCG TGCCAACATT
    GCTGCCATCA CTGAATCAGA CAAGTTCTTC ATCAACGGCT CCAACTGGGA AGGCATCCTG
    GGGCTGGCCT ATGCTGAGAT TGCCAGGCCT GACGACTCCC TGGAGCCTTT CTTTGACTCT
    CTGGTAAAGC AGACCCACGT TCCCAACCTC TTCTCCCTGC AGCTTTGTGG TGCTGGCTTC
    CCCCTCAACC AGTCTGAAGT GCTGGCCTCT GTCGGAGGGA GCATGATCAT TGGAGGTATC
    GACCACTCGC TGTACACAGG CAGTCTCTGG TATACACCCA TCCGGCGGGA GTGGTATTAT
    GAGGTGATCA TTGTGCGGGT GGAGATCAAT GGACAGGATC TGAAAATGGA CTGCAAGGAG
    TACAACTATG ACAAGAGCAT TGTGGACAGT GGCACCACCA ACCTTCGTTT GCCCAAGAAA
    GTGTTTGAAG CTGCAGTCAA ATCCATCAAG GCAGCCTCCT CCACGGAGAA GTTCCCTGAT
    GGTTTCTGGC TAGGAGAGCA GCTGGTGTGC TGGCAAGCAG GCACCACCCC TTGGAACATT
    TTCCCAGTCA TCTCACTCTA CCTAATGGGT GAGGTTACCA ACCAGTCCTT CCGCATCACC
    ATCCTTCCGC AGCAATACCT GCGGCCAGTG GAAGATGTGG CCACGTCCCA AGACGACTGT
    TACAAGTTTG CCATCTCACA GTCATCCACG GGCACTGTTA TGGGAGCTGT TATCATGGAG
    GGCTTCTACG TTGTCTTTGA TCGGGCCCGA AAACGAATTG GCTTTGCTGT CAGCGCTTGC
    CATGTGCACG ATGAGTTCAG GACGGCAGCG GTGGAAGGCC CTTTTGTCAC CTTGGACATG
    GAAGACTGTG GCTACAACAT TCCACAGACA GATGAGTCAA CCCTCATGAC CATAGCCTAT
    GTCATGGCTG CCATCTGCGC CCTCTTCATG CTGCCACTCT GCCTCATGGT GTGTCAGTGG
    CGCTGCCTCC GCTGCCTGCG CCAGCAGCAT GATGACTTTG CTGATGACAT CTCCCTGCTG
    AAGTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu18091
    Clone ID Related Accession (Same CDS sequence) NM_001207048.2 , NM_001207048.1
    Accession Version NM_001207048.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1206bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-03-11
    Organism Homo sapiens(human)
    Product beta-secretase 1 isoform E
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC343475.1, AK296535.1, AB177847.1 and BM996673.1. Transcript Variant: This variant (e) lacks two exons from the 5' end and has an alternate 5' exon, compared to variant a. The resulting isoform (E) has a shorter and distinct N-terminus, and lacks a predicted signal peptide compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.262644.1, SRR1803617.77297.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGTTCCCT TCATCTATCT GCAAGCCCAC TTTACACTCT GTTCTGGGTG GTCCAGCACA 
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGGTAAG CATCCCCCAT GGCCCCAACG TCACTGTGCG TGCCAACATT
    GCTGCCATCA CTGAATCAGA CAAGTTCTTC ATCAACGGCT CCAACTGGGA AGGCATCCTG
    GGGCTGGCCT ATGCTGAGAT TGCCAGGCCT GACGACTCCC TGGAGCCTTT CTTTGACTCT
    CTGGTAAAGC AGACCCACGT TCCCAACCTC TTCTCCCTGC AGCTTTGTGG TGCTGGCTTC
    CCCCTCAACC AGTCTGAAGT GCTGGCCTCT GTCGGAGGGA GCATGATCAT TGGAGGTATC
    GACCACTCGC TGTACACAGG CAGTCTCTGG TATACACCCA TCCGGCGGGA GTGGTATTAT
    GAGGTGATCA TTGTGCGGGT GGAGATCAAT GGACAGGATC TGAAAATGGA CTGCAAGGAG
    TACAACTATG ACAAGAGCAT TGTGGACAGT GGCACCACCA ACCTTCGTTT GCCCAAGAAA
    GTGTTTGAAG CTGCAGTCAA ATCCATCAAG GCAGCCTCCT CCACGGAGAA GTTCCCTGAT
    GGTTTCTGGC TAGGAGAGCA GCTGGTGTGC TGGCAAGCAG GCACCACCCC TTGGAACATT
    TTCCCAGTCA TCTCACTCTA CCTAATGGGT GAGGTTACCA ACCAGTCCTT CCGCATCACC
    ATCCTTCCGC AGCAATACCT GCGGCCAGTG GAAGATGTGG CCACGTCCCA AGACGACTGT
    TACAAGTTTG CCATCTCACA GTCATCCACG GGCACTGTTA TGGGAGCTGT TATCATGGAG
    GGCTTCTACG TTGTCTTTGA TCGGGCCCGA AAACGAATTG GCTTTGCTGT CAGCGCTTGC
    CATGTGCACG ATGAGTTCAG GACGGCAGCG GTGGAAGGCC CTTTTGTCAC CTTGGACATG
    GAAGACTGTG GCTACAACAT TCCACAGACA GATGAGTCAA CCCTCATGAC CATAGCCTAT
    GTCATGGCTG CCATCTGCGC CCTCTTCATG CTGCCACTCT GCCTCATGGT GTGTCAGTGG
    CGCTGCCTCC GCTGCCTGCG CCAGCAGCAT GATGACTTTG CTGATGACAT CTCCCTGCTG
    AAGTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193977.1
    CDS124..1329
    Translation

    Target ORF information:

    RefSeq Version NM_001207048.1
    Organism Homo sapiens(human)
    Definition Homo sapiens beta-secretase 1 (BACE1), transcript variant e, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001207048.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGTTCCCT TCATCTATCT GCAAGCCCAC TTTACACTCT GTTCTGGGTG GTCCAGCACA 
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGGTAAG CATCCCCCAT GGCCCCAACG TCACTGTGCG TGCCAACATT
    GCTGCCATCA CTGAATCAGA CAAGTTCTTC ATCAACGGCT CCAACTGGGA AGGCATCCTG
    GGGCTGGCCT ATGCTGAGAT TGCCAGGCCT GACGACTCCC TGGAGCCTTT CTTTGACTCT
    CTGGTAAAGC AGACCCACGT TCCCAACCTC TTCTCCCTGC AGCTTTGTGG TGCTGGCTTC
    CCCCTCAACC AGTCTGAAGT GCTGGCCTCT GTCGGAGGGA GCATGATCAT TGGAGGTATC
    GACCACTCGC TGTACACAGG CAGTCTCTGG TATACACCCA TCCGGCGGGA GTGGTATTAT
    GAGGTGATCA TTGTGCGGGT GGAGATCAAT GGACAGGATC TGAAAATGGA CTGCAAGGAG
    TACAACTATG ACAAGAGCAT TGTGGACAGT GGCACCACCA ACCTTCGTTT GCCCAAGAAA
    GTGTTTGAAG CTGCAGTCAA ATCCATCAAG GCAGCCTCCT CCACGGAGAA GTTCCCTGAT
    GGTTTCTGGC TAGGAGAGCA GCTGGTGTGC TGGCAAGCAG GCACCACCCC TTGGAACATT
    TTCCCAGTCA TCTCACTCTA CCTAATGGGT GAGGTTACCA ACCAGTCCTT CCGCATCACC
    ATCCTTCCGC AGCAATACCT GCGGCCAGTG GAAGATGTGG CCACGTCCCA AGACGACTGT
    TACAAGTTTG CCATCTCACA GTCATCCACG GGCACTGTTA TGGGAGCTGT TATCATGGAG
    GGCTTCTACG TTGTCTTTGA TCGGGCCCGA AAACGAATTG GCTTTGCTGT CAGCGCTTGC
    CATGTGCACG ATGAGTTCAG GACGGCAGCG GTGGAAGGCC CTTTTGTCAC CTTGGACATG
    GAAGACTGTG GCTACAACAT TCCACAGACA GATGAGTCAA CCCTCATGAC CATAGCCTAT
    GTCATGGCTG CCATCTGCGC CCTCTTCATG CTGCCACTCT GCCTCATGGT GTGTCAGTGG
    CGCTGCCTCC GCTGCCTGCG CCAGCAGCAT GATGACTTTG CTGATGACAT CTCCCTGCTG
    AAGTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu18219
    Clone ID Related Accession (Same CDS sequence) NM_001207049.1 , NM_001207049.2
    Accession Version NM_001207049.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1131bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-03-11
    Organism Homo sapiens(human)
    Product beta-secretase 1 isoform F
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC343475.1, AK296015.1, AB032975.2 and BM996673.1. Transcript Variant: This variant (f) lacks two exons from the 5' end and has an alternate 5' exon and an alternate splice site in the coding region, compared to variant a. The resulting isoform (F) is shorter and lacks a predicted signal peptide compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.245781.1, SRR1803617.249289.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGTTCCCT TCATCTATCT GCAAGCCCAC TTTACACTCT GTTCTGGGTG GTCCAGCACA 
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGGTAAG CATCCCCCAT GGCCCCAACG TCACTGTGCG TGCCAACATT
    GCTGCCATCA CTGAATCAGA CAAGTTCTTC ATCAACGGCT CCAACTGGGA AGGCATCCTG
    GGGCTGGCCT ATGCTGAGAT TGCCAGGCTT TGTGGTGCTG GCTTCCCCCT CAACCAGTCT
    GAAGTGCTGG CCTCTGTCGG AGGGAGCATG ATCATTGGAG GTATCGACCA CTCGCTGTAC
    ACAGGCAGTC TCTGGTATAC ACCCATCCGG CGGGAGTGGT ATTATGAGGT GATCATTGTG
    CGGGTGGAGA TCAATGGACA GGATCTGAAA ATGGACTGCA AGGAGTACAA CTATGACAAG
    AGCATTGTGG ACAGTGGCAC CACCAACCTT CGTTTGCCCA AGAAAGTGTT TGAAGCTGCA
    GTCAAATCCA TCAAGGCAGC CTCCTCCACG GAGAAGTTCC CTGATGGTTT CTGGCTAGGA
    GAGCAGCTGG TGTGCTGGCA AGCAGGCACC ACCCCTTGGA ACATTTTCCC AGTCATCTCA
    CTCTACCTAA TGGGTGAGGT TACCAACCAG TCCTTCCGCA TCACCATCCT TCCGCAGCAA
    TACCTGCGGC CAGTGGAAGA TGTGGCCACG TCCCAAGACG ACTGTTACAA GTTTGCCATC
    TCACAGTCAT CCACGGGCAC TGTTATGGGA GCTGTTATCA TGGAGGGCTT CTACGTTGTC
    TTTGATCGGG CCCGAAAACG AATTGGCTTT GCTGTCAGCG CTTGCCATGT GCACGATGAG
    TTCAGGACGG CAGCGGTGGA AGGCCCTTTT GTCACCTTGG ACATGGAAGA CTGTGGCTAC
    AACATTCCAC AGACAGATGA GTCAACCCTC ATGACCATAG CCTATGTCAT GGCTGCCATC
    TGCGCCCTCT TCATGCTGCC ACTCTGCCTC ATGGTGTGTC AGTGGCGCTG CCTCCGCTGC
    CTGCGCCAGC AGCATGATGA CTTTGCTGAT GACATCTCCC TGCTGAAGTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193978.1
    CDS124..1254
    Translation

    Target ORF information:

    RefSeq Version NM_001207049.1
    Organism Homo sapiens(human)
    Definition Homo sapiens beta-secretase 1 (BACE1), transcript variant f, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001207049.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGTTCCCT TCATCTATCT GCAAGCCCAC TTTACACTCT GTTCTGGGTG GTCCAGCACA 
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGGTAAG CATCCCCCAT GGCCCCAACG TCACTGTGCG TGCCAACATT
    GCTGCCATCA CTGAATCAGA CAAGTTCTTC ATCAACGGCT CCAACTGGGA AGGCATCCTG
    GGGCTGGCCT ATGCTGAGAT TGCCAGGCTT TGTGGTGCTG GCTTCCCCCT CAACCAGTCT
    GAAGTGCTGG CCTCTGTCGG AGGGAGCATG ATCATTGGAG GTATCGACCA CTCGCTGTAC
    ACAGGCAGTC TCTGGTATAC ACCCATCCGG CGGGAGTGGT ATTATGAGGT GATCATTGTG
    CGGGTGGAGA TCAATGGACA GGATCTGAAA ATGGACTGCA AGGAGTACAA CTATGACAAG
    AGCATTGTGG ACAGTGGCAC CACCAACCTT CGTTTGCCCA AGAAAGTGTT TGAAGCTGCA
    GTCAAATCCA TCAAGGCAGC CTCCTCCACG GAGAAGTTCC CTGATGGTTT CTGGCTAGGA
    GAGCAGCTGG TGTGCTGGCA AGCAGGCACC ACCCCTTGGA ACATTTTCCC AGTCATCTCA
    CTCTACCTAA TGGGTGAGGT TACCAACCAG TCCTTCCGCA TCACCATCCT TCCGCAGCAA
    TACCTGCGGC CAGTGGAAGA TGTGGCCACG TCCCAAGACG ACTGTTACAA GTTTGCCATC
    TCACAGTCAT CCACGGGCAC TGTTATGGGA GCTGTTATCA TGGAGGGCTT CTACGTTGTC
    TTTGATCGGG CCCGAAAACG AATTGGCTTT GCTGTCAGCG CTTGCCATGT GCACGATGAG
    TTCAGGACGG CAGCGGTGGA AGGCCCTTTT GTCACCTTGG ACATGGAAGA CTGTGGCTAC
    AACATTCCAC AGACAGATGA GTCAACCCTC ATGACCATAG CCTATGTCAT GGCTGCCATC
    TGCGCCCTCT TCATGCTGCC ACTCTGCCTC ATGGTGTGTC AGTGGCGCTG CCTCCGCTGC
    CTGCGCCAGC AGCATGATGA CTTTGCTGAT GACATCTCCC TGCTGAAGTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu18219
    Clone ID Related Accession (Same CDS sequence) NM_001207049.1 , NM_001207049.2
    Accession Version NM_001207049.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1131bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2020-01-04
    Organism Homo sapiens(human)
    Product beta-secretase 1 isoform F
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP000892.4 and KC877486.1. On Jun 2, 2019 this sequence version replaced NM_001207049.1. Transcript Variant: This variant (f) lacks two exons from the 5' end and has an alternate 5' exon and an alternate splice site in the coding region, compared to variant a. The resulting isoform (F) is shorter and lacks a predicted signal peptide compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.245781.1, SRR1803617.249289.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGTTCCCT TCATCTATCT GCAAGCCCAC TTTACACTCT GTTCTGGGTG GTCCAGCACA 
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGGTAAG CATCCCCCAT GGCCCCAACG TCACTGTGCG TGCCAACATT
    GCTGCCATCA CTGAATCAGA CAAGTTCTTC ATCAACGGCT CCAACTGGGA AGGCATCCTG
    GGGCTGGCCT ATGCTGAGAT TGCCAGGCTT TGTGGTGCTG GCTTCCCCCT CAACCAGTCT
    GAAGTGCTGG CCTCTGTCGG AGGGAGCATG ATCATTGGAG GTATCGACCA CTCGCTGTAC
    ACAGGCAGTC TCTGGTATAC ACCCATCCGG CGGGAGTGGT ATTATGAGGT GATCATTGTG
    CGGGTGGAGA TCAATGGACA GGATCTGAAA ATGGACTGCA AGGAGTACAA CTATGACAAG
    AGCATTGTGG ACAGTGGCAC CACCAACCTT CGTTTGCCCA AGAAAGTGTT TGAAGCTGCA
    GTCAAATCCA TCAAGGCAGC CTCCTCCACG GAGAAGTTCC CTGATGGTTT CTGGCTAGGA
    GAGCAGCTGG TGTGCTGGCA AGCAGGCACC ACCCCTTGGA ACATTTTCCC AGTCATCTCA
    CTCTACCTAA TGGGTGAGGT TACCAACCAG TCCTTCCGCA TCACCATCCT TCCGCAGCAA
    TACCTGCGGC CAGTGGAAGA TGTGGCCACG TCCCAAGACG ACTGTTACAA GTTTGCCATC
    TCACAGTCAT CCACGGGCAC TGTTATGGGA GCTGTTATCA TGGAGGGCTT CTACGTTGTC
    TTTGATCGGG CCCGAAAACG AATTGGCTTT GCTGTCAGCG CTTGCCATGT GCACGATGAG
    TTCAGGACGG CAGCGGTGGA AGGCCCTTTT GTCACCTTGG ACATGGAAGA CTGTGGCTAC
    AACATTCCAC AGACAGATGA GTCAACCCTC ATGACCATAG CCTATGTCAT GGCTGCCATC
    TGCGCCCTCT TCATGCTGCC ACTCTGCCTC ATGGTGTGTC AGTGGCGCTG CCTCCGCTGC
    CTGCGCCAGC AGCATGATGA CTTTGCTGAT GACATCTCCC TGCTGAAGTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001193978.1
    CDS27..1157
    Translation

    Target ORF information:

    RefSeq Version NM_001207049.2
    Organism Homo sapiens(human)
    Definition Homo sapiens beta-secretase 1 (BACE1), transcript variant f, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001207049.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGTTCCCT TCATCTATCT GCAAGCCCAC TTTACACTCT GTTCTGGGTG GTCCAGCACA 
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGGTAAG CATCCCCCAT GGCCCCAACG TCACTGTGCG TGCCAACATT
    GCTGCCATCA CTGAATCAGA CAAGTTCTTC ATCAACGGCT CCAACTGGGA AGGCATCCTG
    GGGCTGGCCT ATGCTGAGAT TGCCAGGCTT TGTGGTGCTG GCTTCCCCCT CAACCAGTCT
    GAAGTGCTGG CCTCTGTCGG AGGGAGCATG ATCATTGGAG GTATCGACCA CTCGCTGTAC
    ACAGGCAGTC TCTGGTATAC ACCCATCCGG CGGGAGTGGT ATTATGAGGT GATCATTGTG
    CGGGTGGAGA TCAATGGACA GGATCTGAAA ATGGACTGCA AGGAGTACAA CTATGACAAG
    AGCATTGTGG ACAGTGGCAC CACCAACCTT CGTTTGCCCA AGAAAGTGTT TGAAGCTGCA
    GTCAAATCCA TCAAGGCAGC CTCCTCCACG GAGAAGTTCC CTGATGGTTT CTGGCTAGGA
    GAGCAGCTGG TGTGCTGGCA AGCAGGCACC ACCCCTTGGA ACATTTTCCC AGTCATCTCA
    CTCTACCTAA TGGGTGAGGT TACCAACCAG TCCTTCCGCA TCACCATCCT TCCGCAGCAA
    TACCTGCGGC CAGTGGAAGA TGTGGCCACG TCCCAAGACG ACTGTTACAA GTTTGCCATC
    TCACAGTCAT CCACGGGCAC TGTTATGGGA GCTGTTATCA TGGAGGGCTT CTACGTTGTC
    TTTGATCGGG CCCGAAAACG AATTGGCTTT GCTGTCAGCG CTTGCCATGT GCACGATGAG
    TTCAGGACGG CAGCGGTGGA AGGCCCTTTT GTCACCTTGG ACATGGAAGA CTGTGGCTAC
    AACATTCCAC AGACAGATGA GTCAACCCTC ATGACCATAG CCTATGTCAT GGCTGCCATC
    TGCGCCCTCT TCATGCTGCC ACTCTGCCTC ATGGTGTGTC AGTGGCGCTG CCTCCGCTGC
    CTGCGCCAGC AGCATGATGA CTTTGCTGAT GACATCTCCC TGCTGAAGTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu17837
    Clone ID Related Accession (Same CDS sequence) NM_138971.3
    Accession Version NM_138971.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1374bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-24
    Organism Homo sapiens(human)
    Product beta-secretase 1 isoform C precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC065492.1, AB032975.2 and BM996673.1. On May 19, 2011 this sequence version replaced NM_138971.2. Transcript Variant: This variant (c) has an alternate splice site in the coding region, compared to variant a. The resulting isoform (C) lacks an internal segment, compared to isoform A. This isoform (C) may not undergo proteolytic processing similar to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB050437.1, AF338817.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 15034149 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGGCCCAAG CCCTGCCCTG GCTCCTGCTG TGGATGGGCG CGGGAGTGCT GCCTGCCCAC 
    GGCACCCAGC ACGGCATCCG GCTGCCCCTG CGCAGCGGCC TGGGGGGCGC CCCCCTGGGG
    CTGCGGCTGC CCCGGGAGAC CGACGAAGAG CCCGAGGAGC CCGGCCGGAG GGGCAGCTTT
    GTGGAGATGG TGGACAACCT GAGGGGCAAG TCGGGGCAGG GCTACTACGT GGAGATGACC
    GTGGGCAGCC CCCCGCAGAC GCTCAACATC CTGGTGGATA CAGGCAGCAG TAACTTTGCA
    GTGGGTGCTG CCCCCCACCC CTTCCTGCAT CGCTACTACC AGAGGCAGCT GTCCAGCACA
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGCCTGA CGACTCCCTG GAGCCTTTCT TTGACTCTCT GGTAAAGCAG
    ACCCACGTTC CCAACCTCTT CTCCCTGCAG CTTTGTGGTG CTGGCTTCCC CCTCAACCAG
    TCTGAAGTGC TGGCCTCTGT CGGAGGGAGC ATGATCATTG GAGGTATCGA CCACTCGCTG
    TACACAGGCA GTCTCTGGTA TACACCCATC CGGCGGGAGT GGTATTATGA GGTGATCATT
    GTGCGGGTGG AGATCAATGG ACAGGATCTG AAAATGGACT GCAAGGAGTA CAACTATGAC
    AAGAGCATTG TGGACAGTGG CACCACCAAC CTTCGTTTGC CCAAGAAAGT GTTTGAAGCT
    GCAGTCAAAT CCATCAAGGC AGCCTCCTCC ACGGAGAAGT TCCCTGATGG TTTCTGGCTA
    GGAGAGCAGC TGGTGTGCTG GCAAGCAGGC ACCACCCCTT GGAACATTTT CCCAGTCATC
    TCACTCTACC TAATGGGTGA GGTTACCAAC CAGTCCTTCC GCATCACCAT CCTTCCGCAG
    CAATACCTGC GGCCAGTGGA AGATGTGGCC ACGTCCCAAG ACGACTGTTA CAAGTTTGCC
    ATCTCACAGT CATCCACGGG CACTGTTATG GGAGCTGTTA TCATGGAGGG CTTCTACGTT
    GTCTTTGATC GGGCCCGAAA ACGAATTGGC TTTGCTGTCA GCGCTTGCCA TGTGCACGAT
    GAGTTCAGGA CGGCAGCGGT GGAAGGCCCT TTTGTCACCT TGGACATGGA AGACTGTGGC
    TACAACATTC CACAGACAGA TGAGTCAACC CTCATGACCA TAGCCTATGT CATGGCTGCC
    ATCTGCGCCC TCTTCATGCT GCCACTCTGC CTCATGGTGT GTCAGTGGCG CTGCCTCCGC
    TGCCTGCGCC AGCAGCATGA TGACTTTGCT GATGACATCT CCCTGCTGAA GTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_620427.1
    CDS462..1835
    Translation

    Target ORF information:

    RefSeq Version NM_138971.3
    Organism Homo sapiens(human)
    Definition Homo sapiens beta-secretase 1 (BACE1), transcript variant c, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_138971.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGGCCCAAG CCCTGCCCTG GCTCCTGCTG TGGATGGGCG CGGGAGTGCT GCCTGCCCAC 
    GGCACCCAGC ACGGCATCCG GCTGCCCCTG CGCAGCGGCC TGGGGGGCGC CCCCCTGGGG
    CTGCGGCTGC CCCGGGAGAC CGACGAAGAG CCCGAGGAGC CCGGCCGGAG GGGCAGCTTT
    GTGGAGATGG TGGACAACCT GAGGGGCAAG TCGGGGCAGG GCTACTACGT GGAGATGACC
    GTGGGCAGCC CCCCGCAGAC GCTCAACATC CTGGTGGATA CAGGCAGCAG TAACTTTGCA
    GTGGGTGCTG CCCCCCACCC CTTCCTGCAT CGCTACTACC AGAGGCAGCT GTCCAGCACA
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGCCTGA CGACTCCCTG GAGCCTTTCT TTGACTCTCT GGTAAAGCAG
    ACCCACGTTC CCAACCTCTT CTCCCTGCAG CTTTGTGGTG CTGGCTTCCC CCTCAACCAG
    TCTGAAGTGC TGGCCTCTGT CGGAGGGAGC ATGATCATTG GAGGTATCGA CCACTCGCTG
    TACACAGGCA GTCTCTGGTA TACACCCATC CGGCGGGAGT GGTATTATGA GGTGATCATT
    GTGCGGGTGG AGATCAATGG ACAGGATCTG AAAATGGACT GCAAGGAGTA CAACTATGAC
    AAGAGCATTG TGGACAGTGG CACCACCAAC CTTCGTTTGC CCAAGAAAGT GTTTGAAGCT
    GCAGTCAAAT CCATCAAGGC AGCCTCCTCC ACGGAGAAGT TCCCTGATGG TTTCTGGCTA
    GGAGAGCAGC TGGTGTGCTG GCAAGCAGGC ACCACCCCTT GGAACATTTT CCCAGTCATC
    TCACTCTACC TAATGGGTGA GGTTACCAAC CAGTCCTTCC GCATCACCAT CCTTCCGCAG
    CAATACCTGC GGCCAGTGGA AGATGTGGCC ACGTCCCAAG ACGACTGTTA CAAGTTTGCC
    ATCTCACAGT CATCCACGGG CACTGTTATG GGAGCTGTTA TCATGGAGGG CTTCTACGTT
    GTCTTTGATC GGGCCCGAAA ACGAATTGGC TTTGCTGTCA GCGCTTGCCA TGTGCACGAT
    GAGTTCAGGA CGGCAGCGGT GGAAGGCCCT TTTGTCACCT TGGACATGGA AGACTGTGGC
    TACAACATTC CACAGACAGA TGAGTCAACC CTCATGACCA TAGCCTATGT CATGGCTGCC
    ATCTGCGCCC TCTTCATGCT GCCACTCTGC CTCATGGTGT GTCAGTGGCG CTGCCTCCGC
    TGCCTGCGCC AGCAGCATGA TGACTTTGCT GATGACATCT CCCTGCTGAA GTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu18478
    Clone ID Related Accession (Same CDS sequence) NM_138972.3
    Accession Version NM_138972.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1431bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-27
    Organism Homo sapiens(human)
    Product beta-secretase 1 isoform B precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC065492.1, AB032975.2 and BM996673.1. On May 19, 2011 this sequence version replaced NM_138972.2. Transcript Variant: This variant (b) has an alternate splice site in the coding region, compared to variant a. The resulting isoform (B) lacks an internal segment, compared to isoform A. This isoform (B) may not undergo proteolytic processing similar to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.199804.1, SRR1660805.250212.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 15034149 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGCCCAAG CCCTGCCCTG GCTCCTGCTG TGGATGGGCG CGGGAGTGCT GCCTGCCCAC 
    GGCACCCAGC ACGGCATCCG GCTGCCCCTG CGCAGCGGCC TGGGGGGCGC CCCCCTGGGG
    CTGCGGCTGC CCCGGGAGAC CGACGAAGAG CCCGAGGAGC CCGGCCGGAG GGGCAGCTTT
    GTGGAGATGG TGGACAACCT GAGGGGCAAG TCGGGGCAGG GCTACTACGT GGAGATGACC
    GTGGGCAGCC CCCCGCAGAC GCTCAACATC CTGGTGGATA CAGGCAGCAG TAACTTTGCA
    GTGGGTGCTG CCCCCCACCC CTTCCTGCAT CGCTACTACC AGAGGCAGCT GTCCAGCACA
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGGTAAG CATCCCCCAT GGCCCCAACG TCACTGTGCG TGCCAACATT
    GCTGCCATCA CTGAATCAGA CAAGTTCTTC ATCAACGGCT CCAACTGGGA AGGCATCCTG
    GGGCTGGCCT ATGCTGAGAT TGCCAGGCTT TGTGGTGCTG GCTTCCCCCT CAACCAGTCT
    GAAGTGCTGG CCTCTGTCGG AGGGAGCATG ATCATTGGAG GTATCGACCA CTCGCTGTAC
    ACAGGCAGTC TCTGGTATAC ACCCATCCGG CGGGAGTGGT ATTATGAGGT GATCATTGTG
    CGGGTGGAGA TCAATGGACA GGATCTGAAA ATGGACTGCA AGGAGTACAA CTATGACAAG
    AGCATTGTGG ACAGTGGCAC CACCAACCTT CGTTTGCCCA AGAAAGTGTT TGAAGCTGCA
    GTCAAATCCA TCAAGGCAGC CTCCTCCACG GAGAAGTTCC CTGATGGTTT CTGGCTAGGA
    GAGCAGCTGG TGTGCTGGCA AGCAGGCACC ACCCCTTGGA ACATTTTCCC AGTCATCTCA
    CTCTACCTAA TGGGTGAGGT TACCAACCAG TCCTTCCGCA TCACCATCCT TCCGCAGCAA
    TACCTGCGGC CAGTGGAAGA TGTGGCCACG TCCCAAGACG ACTGTTACAA GTTTGCCATC
    TCACAGTCAT CCACGGGCAC TGTTATGGGA GCTGTTATCA TGGAGGGCTT CTACGTTGTC
    TTTGATCGGG CCCGAAAACG AATTGGCTTT GCTGTCAGCG CTTGCCATGT GCACGATGAG
    TTCAGGACGG CAGCGGTGGA AGGCCCTTTT GTCACCTTGG ACATGGAAGA CTGTGGCTAC
    AACATTCCAC AGACAGATGA GTCAACCCTC ATGACCATAG CCTATGTCAT GGCTGCCATC
    TGCGCCCTCT TCATGCTGCC ACTCTGCCTC ATGGTGTGTC AGTGGCGCTG CCTCCGCTGC
    CTGCGCCAGC AGCATGATGA CTTTGCTGAT GACATCTCCC TGCTGAAGTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_620428.1
    CDS462..1892
    Translation

    Target ORF information:

    RefSeq Version NM_138972.3
    Organism Homo sapiens(human)
    Definition Homo sapiens beta-secretase 1 (BACE1), transcript variant b, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_138972.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGCCCAAG CCCTGCCCTG GCTCCTGCTG TGGATGGGCG CGGGAGTGCT GCCTGCCCAC 
    GGCACCCAGC ACGGCATCCG GCTGCCCCTG CGCAGCGGCC TGGGGGGCGC CCCCCTGGGG
    CTGCGGCTGC CCCGGGAGAC CGACGAAGAG CCCGAGGAGC CCGGCCGGAG GGGCAGCTTT
    GTGGAGATGG TGGACAACCT GAGGGGCAAG TCGGGGCAGG GCTACTACGT GGAGATGACC
    GTGGGCAGCC CCCCGCAGAC GCTCAACATC CTGGTGGATA CAGGCAGCAG TAACTTTGCA
    GTGGGTGCTG CCCCCCACCC CTTCCTGCAT CGCTACTACC AGAGGCAGCT GTCCAGCACA
    TACCGGGACC TCCGGAAGGG TGTGTATGTG CCCTACACCC AGGGCAAGTG GGAAGGGGAG
    CTGGGCACCG ACCTGGTAAG CATCCCCCAT GGCCCCAACG TCACTGTGCG TGCCAACATT
    GCTGCCATCA CTGAATCAGA CAAGTTCTTC ATCAACGGCT CCAACTGGGA AGGCATCCTG
    GGGCTGGCCT ATGCTGAGAT TGCCAGGCTT TGTGGTGCTG GCTTCCCCCT CAACCAGTCT
    GAAGTGCTGG CCTCTGTCGG AGGGAGCATG ATCATTGGAG GTATCGACCA CTCGCTGTAC
    ACAGGCAGTC TCTGGTATAC ACCCATCCGG CGGGAGTGGT ATTATGAGGT GATCATTGTG
    CGGGTGGAGA TCAATGGACA GGATCTGAAA ATGGACTGCA AGGAGTACAA CTATGACAAG
    AGCATTGTGG ACAGTGGCAC CACCAACCTT CGTTTGCCCA AGAAAGTGTT TGAAGCTGCA
    GTCAAATCCA TCAAGGCAGC CTCCTCCACG GAGAAGTTCC CTGATGGTTT CTGGCTAGGA
    GAGCAGCTGG TGTGCTGGCA AGCAGGCACC ACCCCTTGGA ACATTTTCCC AGTCATCTCA
    CTCTACCTAA TGGGTGAGGT TACCAACCAG TCCTTCCGCA TCACCATCCT TCCGCAGCAA
    TACCTGCGGC CAGTGGAAGA TGTGGCCACG TCCCAAGACG ACTGTTACAA GTTTGCCATC
    TCACAGTCAT CCACGGGCAC TGTTATGGGA GCTGTTATCA TGGAGGGCTT CTACGTTGTC
    TTTGATCGGG CCCGAAAACG AATTGGCTTT GCTGTCAGCG CTTGCCATGT GCACGATGAG
    TTCAGGACGG CAGCGGTGGA AGGCCCTTTT GTCACCTTGG ACATGGAAGA CTGTGGCTAC
    AACATTCCAC AGACAGATGA GTCAACCCTC ATGACCATAG CCTATGTCAT GGCTGCCATC
    TGCGCCCTCT TCATGCTGCC ACTCTGCCTC ATGGTGTGTC AGTGGCGCTG CCTCCGCTGC
    CTGCGCCAGC AGCATGATGA CTTTGCTGAT GACATCTCCC TGCTGAAGTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.