UNC13A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	UNC13A
Entrez Gene ID	23025
Full Name	unc-13 homolog A
Synonyms	Munc13-1
General protein information	Preferred Names unc-13 homolog A Names protein unc-13 homolog A
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.11
Summary	This gene encodes a member of the UNC13 family. UNC13 proteins bind to phorbol esters and diacylglycerol and play important roles in neurotransmitter release at synapses. Single nucleotide polymorphisms in this gene may be associated with sporadic amyotrophic lateral sclerosis. [provided by RefSeq, Feb 2012].
Disorder MIM:	609894

mRNA and Protein(s)

mRNA	Protein	Name
NM_001080421.2	NP_001073890.2	protein unc-13 homolog A
XM_011527811.2	XP_011526113.1	protein unc-13 homolog A isoform X3
XM_011527810.2	XP_011526112.1	protein unc-13 homolog A isoform X2
XM_017026502.1	XP_016881991.1	protein unc-13 homolog A isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	UNC13A	XP_002688619.2
Rattus norvegicus (Norway rat)	Unc13a	NP_074052.1
Danio rerio (zebrafish)	si:dkey-110c1.7	NP_001038630.1
Xenopus tropicalis (tropical clawed frog)	LOC100492289	XP_002938873.2
Homo sapiens (human)	UNC13A	NP_001073890.2
Gallus gallus (chicken)	LOC430487	XP_428042.4
Canis lupus familiaris (dog)	UNC13A	XP_005633256.1
Caenorhabditis elegans (roundworm)	unc-13	NP_001021874.1
Mus musculus (house mouse)	Unc13a	NP_001025044.2
Drosophila melanogaster (fruit fly)	unc-13	NP_651949.2

Gene Ontology
Bibliography

Related articles in PubMed

Rare genetic variation in UNC13A may modify survival in amyotrophic lateral sclerosis.
Gaastra B, Shatunov A, Pulit S, Jones AR, Sproviero W, Gillett A, Chen Z, Kirby J, Fogh I, Powell JF, Leigh PN, Morrison KE, Shaw PJ, Shaw CE, van den Berg LH, Veldink JH, Lewis CM, Al-Chalabi A
Amyotrophic lateral sclerosis & frontotemporal degeneration17(7-8)593-599(2016 Oct - Nov)

Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder.
Lipstein N, Verhoeven-Duif NM, Michelassi FE, Calloway N, van Hasselt PM, Pienkowska K, van Haaften G, van Haelst MM, van Empelen R, Cuppen I, van Teeseling HC, Evelein AM, Vorstman JA, Thoms S, Jahn O, Duran KJ, Monroe GR, Ryan TA, Taschenberger H, Dittman JS, Rhee JS, Visser G, Jans JJ, Brose N
The Journal of clinical investigation127(3)1005-1018(2017 Mar)

UNC13A confers risk for sporadic ALS and influences survival in a Spanish cohort.
Vidal-Taboada JM, Lopez-Lopez A, Salvado M, Lorenzo L, Garcia C, Mahy N, Rodr?guez MJ, Gamez J
Journal of neurology262(10)2285-92(2015 Oct)

C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis.
Diekstra FP, Van Deerlin VM, van Swieten JC, Al-Chalabi A, Ludolph AC, Weishaupt JH, Hardiman O, Landers JE, Brown RH Jr, van Es MA, Pasterkamp RJ, Koppers M, Andersen PM, Estrada K, Rivadeneira F, Hofman A, Uitterlinden AG, van Damme P, Melki J, Meininger V, Shatunov A, Shaw CE, Leigh PN, Shaw PJ, Morrison KE, Fogh I, Chi? A, Traynor BJ, Czell D, Weber M, Heutink P, de Bakker PI, Silani V, Robberecht W, van den Berg LH, Veldink JH
Annals of neurology76(1)120-33(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demonstrated that the population specific rare variants of UNC13A may modulate survival in ALS in United kingdom.
Title: Rare genetic variation in UNC13A may modify survival in amyotrophic lateral sclerosis.

Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder
Title: Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder.

UNC13A rs12608932 is a risk factor for ALS and a modifying factor for survival and disease progression rate in a Spanish cohort.
Title: UNC13A confers risk for sporadic ALS and influences survival in a Spanish cohort.

UNC13A provides a novel link between amyotrophic lateral sclerosis and frontotemporal dementia and identifies changes in neurotransmitter release and synaptic function as a converging mechanism in the pathogenesis of ALS and FTD-TDP.
Title: C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis.

Munc13-1, on account of its role in both insulin and neurotransmitter exocytosis and through its binding properties, may be an important factor contributing to the development or progression of diabetic neuropathy.
Title: Reduced expression of Munc13-1 in human and porcine diabetic peripheral nerve.

The following UNC13A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UNC13A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu01320	NM_001080421.2 Latest version!	Homo sapiens unc-13 homolog A (UNC13A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$679.50-$951.30 $1359.00
OHu65310	XM_011527810.2 Latest version!	Homo sapiens unc-13 homolog A (UNC13A), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$951.30 $1359.00
OHu65311	XM_011527811.2 Latest version!	Homo sapiens unc-13 homolog A (UNC13A), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$951.30 $1359.00
OHu88318	XM_017026502.1 Latest version!	Homo sapiens unc-13 homolog A (UNC13A), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$951.30 $1359.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

UNC13A ( NM_001080421.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073890.2 Homo sapiens unc-13 homolog A (UNC13A), mRNA.

Price & Availability↑

CloneID	OHu01320
Clone ID Related Accession (Same CDS sequence)	NM_001080421.2
Accession Version	NM_001080421.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5112bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	protein unc-13 homolog A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC008761.8, AB028955.2, DA236619.1 and R60139.1. This sequence is a reference standard in the RefSeqGene project. On Jan 14, 2010 this sequence version replaced NM_001080421.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB028955.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCTCTGC TTTGCGTTGG AGTCAAAAAA GCCAAGTTTG ATGGTGCCCA AGAGAAATTC 
AACACGTACG TGACCCTGAA AGTGCAGAAT GTCAAGAGCA CGACCATCGC GGTGCGGGGC 
AGCCAGCCCA GCTGGGAGCA GGATTTCATG TTCGAGATTA ACCGTCTGGA TTTGGGACTG 
ACGGTGGAGG TGTGGAATAA GGGTCTCATC TGGGACACAA TGGTGGGCAC TGTGTGGATC 
CCACTGAGGA CCATCCGCCA GTCCAATGAG GAGGGCCCTG GAGAGTGGCT GACGCTGGAC 
TCCCAGGTCA TCATGGCAGA CAGTGAGATC TGTGGCACCA AGGACCCCAC CTTCCACCGC 
ATCCTCCTGG ACACGCGCTT TGAGCTACCC TTAGACATTC CTGAAGAGGA GGCTCGCTAC 
TGGGCCAAGA AGCTGGAGCA GCTCAATGCT ATGCGGGACC AGGATGAATA TTCGTTCCAA 
GATGAGCAAG ACAAGCCTCT GCCTGTCCCC AGCAACCAGT GCTGCAACTG GAATTATTTT 
GGCTGGGGTG AGCAGCACAA CGATGACCCC GACAGTGCAG TGGATGATCG TGACAGTGAC 
TACCGCAGTG AAACGAGCAA CAGCATCCCG CCGCCCTATT ATACTACGTC ACAACCCAAC 
GCCTCAGTCC ACCAATATTC TGTTCGCCCA CCACCCCTGG GCTCCCGGGA GTCCTACAGT 
GACTCCATGC ACAGTTACGA GGAGTTCTCT GAGCCACAAG CCCTCAGCCC CACGGGTAGC 
AGCCGCTATG CCTCTTCCGG GGAGCTGAGC CAGGGAAGCT CTCAGCTGAG CGAGGACTTC 
GACCCTGACG AGCACAGCCT GCAGGGCTCC GACATGGAGG ATGAGCGGGA CCGGGACTCC 
TACCACTCCT GCCACAGCTC GGTCAGCTAC CACAAAGACT CGCCTCGCTG GGACCAGGAT 
GAGGAAGAGC TGGAGGAGGA CCTGGAGGAC TTCCTGGAGG AGGAGGAGCT GCCTGAAGAT 
GAGGAGGAGC TGGAGGAGGA GGAGGAGGAG GTGCCTGACG ATTTGGGCAG CTATGCCCAG 
CGTGAAGACG TAGCTGTGGC TGAGCCCAAA GACTTCAAAC GCATCAGCCT CCCGCCAGCT 
GCCCCAGGGA AGGAGGACAA GGCCCCAGTG GCACCCACCG AGGCCCCCGA CATGGCCAAG 
GTGGCCCCCA AGCCAGCCAC GCCCGACAAG GTGCCTGCAG CTGAGCAGAT CCCTGAGGCT 
GAGCCACCCA AGGACGAGGA GAGTTTCAGG CCGAGAGAGG ATGAGGAAGG CCAGGAGGGG 
CAGGACTCCA TGTCCAGGGC CAAGGCCAAC TGGCTGCGTG CCTTCAACAA GGTGCGGATG 
CAGCTGCAGG AGGCCCGGGG AGAAGGAGAG ATGTCTAAAT CCCTATGGTT CAAAGGCGGC 
CCAGGGGGCG GTCTCATCAT CATCGACAGC ATGCCAGACA TCCGCAAGAG GAAACCTATC 
CCACTCGTGA GCGACTTGGC CATGTCCCTG GTCCAGTCCA GGAAAGCGGG CATCACCTCG 
GCCTTGGCCT CCAGCACGTT GAACAACGAG GAGCTGAAAA ACCACGTTTA CAAGAAGACC 
CTGCAAGCCT TAATCTACCC CATCTCGTGC ACGACGCCAC ACAACTTCGA AGTGTGGACG 
GCCACCACGC CCACCTACTG CTACGAGTGC GAGGGGCTGC TGTGGGGCAT CGCGAGGCAG 
GGCATGCGCT GCACCGAGTG CGGTGTCAAG TGCCACGAGA AGTGCCAGGA CCTGCTCAAC 
GCCGACTGCC TGCAGCGGGC TGCGGAGAAG AGCTCCAAGC ACGGGGCGGA GGACCGGACA 
CAGAACATCA TCATGGTGCT CAAGGACCGC ATGAAGATCC GGGAGCGCAA CAAGCCCGAG 
ATCTTCGAGC TCATCCAGGA GATCTTCGCG GTGACCAAGA CGGCGCACAC GCAGCAGATG 
AAGGCGGTCA AGCAGAGCGT GCTGGACGGC ACGTCCAAGT GGTCCGCCAA GATCAGCATC 
ACCGTGGTCT GCGCCCAGGG CTTGCAGGCA AAGGACAAGA CAGGATCCAG TGACCCCTAT 
GTCACCGTCC AGGTCGGGAA GACCAAGAAA CGGACAAAAA CCATCTATGG GAACCTCAAC 
CCGGTGTGGG AGGAGAATTT CCACTTTGAA TGTCACAATT CCTCCGACCG CATCAAGGTG 
CGCGTCTGGG ACGAGGATGA CGACATCAAA TCCCGCGTGA AACAGAGGTT CAAGAGGGAA 
TCTGACGATT TCCTGGGGCA GACGATCATT GAGGTGCGGA CGCTCAGCGG CGAGATGGAC 
GTGTGGTACA ACCTGGACAA GCGAACTGAC AAATCTGCCG TGTCGGGTGC CATCCGGCTC 
CACATCAGTG TGGAGATCAA AGGCGAGGAG AAGGTGGCCC CGTACCATGT CCAGTACACC 
TGTCTGCATG AGAACCTGTT CCACTTCGTG ACCGACGTGC AGAACAATGG GGTCGTGAAG 
ATCCCAGATG CCAAGGGTGA CGATGCCTGG AAGGTTTACT ACGATGAGAC AGCCCAGGAG 
ATTGTGGACG AGTTTGCCAT GCGCTACGGC GTCGAGTCCA TCTACCAAGC CATGACCCAC 
TTTGCCTGCC TCTCCTCCAA GTATATGTGC CCAGGGGTGC CTGCCGTCAT GAGCACCCTG 
CTCGCCAACA TCAATGCCTA CTACGCACAC ACCACCGCCT CCACCAACGT GTCTGCCTCC 
GACCGCTTCG CCGCCTCCAA CTTTGGGAAA GAGCGCTTCG TGAAACTCCT GGACCAGCTG 
CATAACTCCC TGCGGATTGA CCTCTCCATG TACCGGAATA ACTTCCCAGC CAGCAGCCCG 
GAGAGACTCC AGGACCTCAA ATCCACTGTG GACCTTCTCA CCAGCATCAC CTTCTTTCGG 
ATGAAGGTAC AAGAACTCCA GAGCCCGCCC CGAGCCAGCC AGGTGGTAAA GGACTGTGTG 
AAAGCCTGCC TTAATTCTAC CTACGAGTAC ATCTTCAATA ACTGCCATGA ACTGTACAGC 
CGGGAGTACC AGACAGACCC GGCCAAGAAG GGGGAAGTTC TCCCAGAGGA ACAGGGGCCC 
AGCATCAAGA ACCTCGACTT CTGGTCCAAG CTGATTACCC TCATAGTGTC CATCATTGAG 
GAAGACAAGA ATTCCTACAC TCCCTGCCTC AACCAGTTTC CCCAGGAGCT GAATGTGGGT 
AAAATCAGCG CTGAAGTGAT GTGGAATCTG TTTGCCCAAG ACATGAAGTA CGCCATGGAG 
GAGCACGACA AGCATCGTCT ATGCAAGAGT GCCGACTACA TGAACCTCCA CTTCAAGGTG 
AAATGGCTCT ACAATGAGTA TGTGACGGAA CTTCCCGCCT TCAAGGACCG CGTGCCTGAG 
TACCCTGCAT GGTTTGAACC CTTCGTCATC CAGTGGCTGG ATGAGAATGA GGAGGTGTCC 
CGGGATTTCC TGCACGGTGC CCTGGAGCGA GACAAGAAGG ATGGGTTCCA GCAGACCTCA 
GAGCATGCCC TATTCTCCTG CTCCGTGGTG GATGTTTTCT CCCAACTCAA CCAGAGCTTT 
GAAATCATCA AGAAACTCGA GTGTCCCGAC CCTCAGATCG TGGGGCACTA CATGAGGCGC 
TTTGCCAAGA CCATCAGTAA TGTGCTCCTC CAGTATGCAG ACATCATCTC CAAGGACTTT 
GCCTCCTACT GCTCCAAGGA GAAGGAGAAA GTGCCCTGCA TTCTCATGAA TAACACTCAA 
CAGCTACGAG TTCAGCTGGA GAAGATGTTC GAAGCCATGG GAGGAAAGGA GCTGGATGCT 
GAAGCCAGTG ACATCCTGAA GGAGCTTCAG GTGAAACTCA ATAACGTCTT GGATGAGCTC 
AGCCGGGTGT TTGCTACCAG CTTCCAGCCG CACATTGAAG AGTGTGTCAA ACAGATGGGT 
GACATCCTTA GCCAGGTTAA GGGCACAGGC AATGTGCCAG CCAGTGCCTG CAGCAGCGTG 
GCCCAGGACG CGGACAATGT GTTGCAGCCC ATCATGGACC TGCTGGACAG CAACCTGACC 
CTCTTTGCCA AAATCTGTGA GAAGACTGTG CTGAAGCGAG TGCTGAAGGA GCTGTGGAAG 
CTGGTTATGA ACACCATGGA GAAAACCATC GTCCTGCCGC CCCTCACTGA CCAGACGATG 
ATCGGGAACC TCTTGAGAAA ACATGGCAAG GGATTAGAAA AGGGCAGGGT GAAATTGCCA 
AGCCACTCAG ACGGAACCCA GATGATCTTC AATGCAGCCA AGGAGCTGGG TCAGCTGTCC 
AAACTCAAGG ATCACATGGT ACGAGAAGAA GCCAAGAGCT TGACCCCAAA GCAGTGCGCG 
GTTGTTGAGT TGGCCCTGGA CACCATCAAG CAATATTTCC ACGCGGGTGG CGTGGGCCTC 
AAGAAGACCT TCCTGGAGAA GAGCCCGGAC CTGCAATCCT TGCGCTATGC CCTGTCGCTC 
TACACGCAGG CCACCGACCT GCTAATCAAG ACCTTTGTAC AGACGCAATC GGCCCAGGGC 
TTGGGTGTAG AAGACCCTGT GGGTGAAGTC TCTGTCCATG TTGAGCTGTT CACTCATCCA 
GGAACTGGGG AACACAAGGT CACAGTGAAA GTGGTGGCTG CCAATGACCT CAAGTGGCAG 
ACTTCTGGCA TCTTCCGGCC GTTCATCGAG GTCAACATCA TTGGGCCCCA GCTCAGCGAC 
AAGAAACGCA AGTTTGCGAC CAAATCCAAG AACAATAGCT GGGCTCCCAA GTACAATGAG 
AGCTTCCAGT TCACGCTGAG CGCCGACGCG GGTCCCGAGT GCTATGAGCT GCAGGTGTGC 
GTCAAGGACT ACTGCTTCGC GCGCGAGGAC CGCACGGTGG GGCTGGCCGT GCTGCAGCTG 
CGTGAGCTGG CCCAGCGCGG GAGCGCCGCC TGCTGGCTGC CGCTCGGCCG CCGCATCCAC 
ATGGACGACA CGGGCCTCAC GGTGCTGCGA ATCCTCTCGC AGCGCAGCAA CGACGAGGTG 
GCCAAGGAGT TCGTGAAGCT CAAGTCGGAC ACGCGCTCCG CCGAGGAGGG CGGTGCCGCG 
CCTGCGCCTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073890.2
CDS	1..5112
Translation	MSLLCVGVKKAKFDGAQEKFNTYVTLKVQNVKSTTIAVRGSQPSWEQDFMFEINRLDLGLTVEVWNKGLIWDTMVGTVWIPLRTIRQSNEEGPGEWLTLDSQVIMADSEICGTKDPTFHRILLDTRFELPLDIPEEEARYWAKKLEQLNAMRDQDEYSFQDEQDKPLPVPSNQCCNWNYFGWGEQHNDDPDSAVDDRDSDYRSETSNSIPPPYYTTSQPNASVHQYSVRPPPLGSRESYSDSMHSYEEFSEPQALSPTGSSRYASSGELSQGSSQLSEDFDPDEHSLQGSDMEDERDRDSYHSCHSSVSYHKDSPRWDQDEEELEEDLEDFLEEEELPEDEEELEEEEEEVPDDLGSYAQREDVAVAEPKDFKRISLPPAAPGKEDKAPVAPTEAPDMAKVAPKPATPDKVPAAEQIPEAEPPKDEESFRPREDEEGQEGQDSMSRAKANWLRAFNKVRMQLQEARGEGEMSKSLWFKGGPGGGLIIIDSMPDIRKRKPIPLVSDLAMSLVQSRKAGITSALASSTLNNEELKNHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDRTQNIIMVLKDRMKIRERNKPEIFELIQEIFAVTKTAHTQQMKAVKQSVLDGTSKWSAKISITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHFECHNSSDRIKVRVWDEDDDIKSRVKQRFKRESDDFLGQTIIEVRTLSGEMDVWYNLDKRTDKSAVSGAIRLHISVEIKGEEKVAPYHVQYTCLHENLFHFVTDVQNNGVVKIPDAKGDDAWKVYYDETAQEIVDEFAMRYGVESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHELYSREYQTDPAKKGEVLPEEQGPSIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVGKISAEVMWNLFAQDMKYAMEEHDKHRLCKSADYMNLHFKVKWLYNEYVTELPAFKDRVPEYPAWFEPFVIQWLDENEEVSRDFLHGALERDKKDGFQQTSEHALFSCSVVDVFSQLNQSFEIIKKLECPDPQIVGHYMRRFAKTISNVLLQYADIISKDFASYCSKEKEKVPCILMNNTQQLRVQLEKMFEAMGGKELDAEASDILKELQVKLNNVLDELSRVFATSFQPHIEECVKQMGDILSQVKGTGNVPASACSSVAQDADNVLQPIMDLLDSNLTLFAKICEKTVLKRVLKELWKLVMNTMEKTIVLPPLTDQTMIGNLLRKHGKGLEKGRVKLPSHSDGTQMIFNAAKELGQLSKLKDHMVREEAKSLTPKQCAVVELALDTIKQYFHAGGVGLKKTFLEKSPDLQSLRYALSLYTQATDLLIKTFVQTQSAQGLGVEDPVGEVSVHVELFTHPGTGEHKVTVKVVAANDLKWQTSGIFRPFIEVNIIGPQLSDKKRKFATKSKNNSWAPKYNESFQFTLSADAGPECYELQVCVKDYCFAREDRTVGLAVLQLRELAQRGSAACWLPLGRRIHMDDTGLTVLRILSQRSNDEVAKEFVKLKSDTRSAEEGGAAPAP

Target ORF information:

RefSeq Version	NM_001080421.2
Organism	Homo sapiens(human)
Definition	Homo sapiens unc-13 homolog A (UNC13A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080421.2

ORF Insert Sequence:

ATGTCTCTGC TTTGCGTTGG AGTCAAAAAA GCCAAGTTTG ATGGTGCCCA AGAGAAATTC 
AACACGTACG TGACCCTGAA AGTGCAGAAT GTCAAGAGCA CGACCATCGC GGTGCGGGGC 
AGCCAGCCCA GCTGGGAGCA GGATTTCATG TTCGAGATTA ACCGTCTGGA TTTGGGACTG 
ACGGTGGAGG TGTGGAATAA GGGTCTCATC TGGGACACAA TGGTGGGCAC TGTGTGGATC 
CCACTGAGGA CCATCCGCCA GTCCAATGAG GAGGGCCCTG GAGAGTGGCT GACGCTGGAC 
TCCCAGGTCA TCATGGCAGA CAGTGAGATC TGTGGCACCA AGGACCCCAC CTTCCACCGC 
ATCCTCCTGG ACACGCGCTT TGAGCTACCC TTAGACATTC CTGAAGAGGA GGCTCGCTAC 
TGGGCCAAGA AGCTGGAGCA GCTCAATGCT ATGCGGGACC AGGATGAATA TTCGTTCCAA 
GATGAGCAAG ACAAGCCTCT GCCTGTCCCC AGCAACCAGT GCTGCAACTG GAATTATTTT 
GGCTGGGGTG AGCAGCACAA CGATGACCCC GACAGTGCAG TGGATGATCG TGACAGTGAC 
TACCGCAGTG AAACGAGCAA CAGCATCCCG CCGCCCTATT ATACTACGTC ACAACCCAAC 
GCCTCAGTCC ACCAATATTC TGTTCGCCCA CCACCCCTGG GCTCCCGGGA GTCCTACAGT 
GACTCCATGC ACAGTTACGA GGAGTTCTCT GAGCCACAAG CCCTCAGCCC CACGGGTAGC 
AGCCGCTATG CCTCTTCCGG GGAGCTGAGC CAGGGAAGCT CTCAGCTGAG CGAGGACTTC 
GACCCTGACG AGCACAGCCT GCAGGGCTCC GACATGGAGG ATGAGCGGGA CCGGGACTCC 
TACCACTCCT GCCACAGCTC GGTCAGCTAC CACAAAGACT CGCCTCGCTG GGACCAGGAT 
GAGGAAGAGC TGGAGGAGGA CCTGGAGGAC TTCCTGGAGG AGGAGGAGCT GCCTGAAGAT 
GAGGAGGAGC TGGAGGAGGA GGAGGAGGAG GTGCCTGACG ATTTGGGCAG CTATGCCCAG 
CGTGAAGACG TAGCTGTGGC TGAGCCCAAA GACTTCAAAC GCATCAGCCT CCCGCCAGCT 
GCCCCAGGGA AGGAGGACAA GGCCCCAGTG GCACCCACCG AGGCCCCCGA CATGGCCAAG 
GTGGCCCCCA AGCCAGCCAC GCCCGACAAG GTGCCTGCAG CTGAGCAGAT CCCTGAGGCT 
GAGCCACCCA AGGACGAGGA GAGTTTCAGG CCGAGAGAGG ATGAGGAAGG CCAGGAGGGG 
CAGGACTCCA TGTCCAGGGC CAAGGCCAAC TGGCTGCGTG CCTTCAACAA GGTGCGGATG 
CAGCTGCAGG AGGCCCGGGG AGAAGGAGAG ATGTCTAAAT CCCTATGGTT CAAAGGCGGC 
CCAGGGGGCG GTCTCATCAT CATCGACAGC ATGCCAGACA TCCGCAAGAG GAAACCTATC 
CCACTCGTGA GCGACTTGGC CATGTCCCTG GTCCAGTCCA GGAAAGCGGG CATCACCTCG 
GCCTTGGCCT CCAGCACGTT GAACAACGAG GAGCTGAAAA ACCACGTTTA CAAGAAGACC 
CTGCAAGCCT TAATCTACCC CATCTCGTGC ACGACGCCAC ACAACTTCGA AGTGTGGACG 
GCCACCACGC CCACCTACTG CTACGAGTGC GAGGGGCTGC TGTGGGGCAT CGCGAGGCAG 
GGCATGCGCT GCACCGAGTG CGGTGTCAAG TGCCACGAGA AGTGCCAGGA CCTGCTCAAC 
GCCGACTGCC TGCAGCGGGC TGCGGAGAAG AGCTCCAAGC ACGGGGCGGA GGACCGGACA 
CAGAACATCA TCATGGTGCT CAAGGACCGC ATGAAGATCC GGGAGCGCAA CAAGCCCGAG 
ATCTTCGAGC TCATCCAGGA GATCTTCGCG GTGACCAAGA CGGCGCACAC GCAGCAGATG 
AAGGCGGTCA AGCAGAGCGT GCTGGACGGC ACGTCCAAGT GGTCCGCCAA GATCAGCATC 
ACCGTGGTCT GCGCCCAGGG CTTGCAGGCA AAGGACAAGA CAGGATCCAG TGACCCCTAT 
GTCACCGTCC AGGTCGGGAA GACCAAGAAA CGGACAAAAA CCATCTATGG GAACCTCAAC 
CCGGTGTGGG AGGAGAATTT CCACTTTGAA TGTCACAATT CCTCCGACCG CATCAAGGTG 
CGCGTCTGGG ACGAGGATGA CGACATCAAA TCCCGCGTGA AACAGAGGTT CAAGAGGGAA 
TCTGACGATT TCCTGGGGCA GACGATCATT GAGGTGCGGA CGCTCAGCGG CGAGATGGAC 
GTGTGGTACA ACCTGGACAA GCGAACTGAC AAATCTGCCG TGTCGGGTGC CATCCGGCTC 
CACATCAGTG TGGAGATCAA AGGCGAGGAG AAGGTGGCCC CGTACCATGT CCAGTACACC 
TGTCTGCATG AGAACCTGTT CCACTTCGTG ACCGACGTGC AGAACAATGG GGTCGTGAAG 
ATCCCAGATG CCAAGGGTGA CGATGCCTGG AAGGTTTACT ACGATGAGAC AGCCCAGGAG 
ATTGTGGACG AGTTTGCCAT GCGCTACGGC GTCGAGTCCA TCTACCAAGC CATGACCCAC 
TTTGCCTGCC TCTCCTCCAA GTATATGTGC CCAGGGGTGC CTGCCGTCAT GAGCACCCTG 
CTCGCCAACA TCAATGCCTA CTACGCACAC ACCACCGCCT CCACCAACGT GTCTGCCTCC 
GACCGCTTCG CCGCCTCCAA CTTTGGGAAA GAGCGCTTCG TGAAACTCCT GGACCAGCTG 
CATAACTCCC TGCGGATTGA CCTCTCCATG TACCGGAATA ACTTCCCAGC CAGCAGCCCG 
GAGAGACTCC AGGACCTCAA ATCCACTGTG GACCTTCTCA CCAGCATCAC CTTCTTTCGG 
ATGAAGGTAC AAGAACTCCA GAGCCCGCCC CGAGCCAGCC AGGTGGTAAA GGACTGTGTG 
AAAGCCTGCC TTAATTCTAC CTACGAGTAC ATCTTCAATA ACTGCCATGA ACTGTACAGC 
CGGGAGTACC AGACAGACCC GGCCAAGAAG GGGGAAGTTC TCCCAGAGGA ACAGGGGCCC 
AGCATCAAGA ACCTCGACTT CTGGTCCAAG CTGATTACCC TCATAGTGTC CATCATTGAG 
GAAGACAAGA ATTCCTACAC TCCCTGCCTC AACCAGTTTC CCCAGGAGCT GAATGTGGGT 
AAAATCAGCG CTGAAGTGAT GTGGAATCTG TTTGCCCAAG ACATGAAGTA CGCCATGGAG 
GAGCACGACA AGCATCGTCT ATGCAAGAGT GCCGACTACA TGAACCTCCA CTTCAAGGTG 
AAATGGCTCT ACAATGAGTA TGTGACGGAA CTTCCCGCCT TCAAGGACCG CGTGCCTGAG 
TACCCTGCAT GGTTTGAACC CTTCGTCATC CAGTGGCTGG ATGAGAATGA GGAGGTGTCC 
CGGGATTTCC TGCACGGTGC CCTGGAGCGA GACAAGAAGG ATGGGTTCCA GCAGACCTCA 
GAGCATGCCC TATTCTCCTG CTCCGTGGTG GATGTTTTCT CCCAACTCAA CCAGAGCTTT 
GAAATCATCA AGAAACTCGA GTGTCCCGAC CCTCAGATCG TGGGGCACTA CATGAGGCGC 
TTTGCCAAGA CCATCAGTAA TGTGCTCCTC CAGTATGCAG ACATCATCTC CAAGGACTTT 
GCCTCCTACT GCTCCAAGGA GAAGGAGAAA GTGCCCTGCA TTCTCATGAA TAACACTCAA 
CAGCTACGAG TTCAGCTGGA GAAGATGTTC GAAGCCATGG GAGGAAAGGA GCTGGATGCT 
GAAGCCAGTG ACATCCTGAA GGAGCTTCAG GTGAAACTCA ATAACGTCTT GGATGAGCTC 
AGCCGGGTGT TTGCTACCAG CTTCCAGCCG CACATTGAAG AGTGTGTCAA ACAGATGGGT 
GACATCCTTA GCCAGGTTAA GGGCACAGGC AATGTGCCAG CCAGTGCCTG CAGCAGCGTG 
GCCCAGGACG CGGACAATGT GTTGCAGCCC ATCATGGACC TGCTGGACAG CAACCTGACC 
CTCTTTGCCA AAATCTGTGA GAAGACTGTG CTGAAGCGAG TGCTGAAGGA GCTGTGGAAG 
CTGGTTATGA ACACCATGGA GAAAACCATC GTCCTGCCGC CCCTCACTGA CCAGACGATG 
ATCGGGAACC TCTTGAGAAA ACATGGCAAG GGATTAGAAA AGGGCAGGGT GAAATTGCCA 
AGCCACTCAG ACGGAACCCA GATGATCTTC AATGCAGCCA AGGAGCTGGG TCAGCTGTCC 
AAACTCAAGG ATCACATGGT ACGAGAAGAA GCCAAGAGCT TGACCCCAAA GCAGTGCGCG 
GTTGTTGAGT TGGCCCTGGA CACCATCAAG CAATATTTCC ACGCGGGTGG CGTGGGCCTC 
AAGAAGACCT TCCTGGAGAA GAGCCCGGAC CTGCAATCCT TGCGCTATGC CCTGTCGCTC 
TACACGCAGG CCACCGACCT GCTAATCAAG ACCTTTGTAC AGACGCAATC GGCCCAGGGC 
TTGGGTGTAG AAGACCCTGT GGGTGAAGTC TCTGTCCATG TTGAGCTGTT CACTCATCCA 
GGAACTGGGG AACACAAGGT CACAGTGAAA GTGGTGGCTG CCAATGACCT CAAGTGGCAG 
ACTTCTGGCA TCTTCCGGCC GTTCATCGAG GTCAACATCA TTGGGCCCCA GCTCAGCGAC 
AAGAAACGCA AGTTTGCGAC CAAATCCAAG AACAATAGCT GGGCTCCCAA GTACAATGAG 
AGCTTCCAGT TCACGCTGAG CGCCGACGCG GGTCCCGAGT GCTATGAGCT GCAGGTGTGC 
GTCAAGGACT ACTGCTTCGC GCGCGAGGAC CGCACGGTGG GGCTGGCCGT GCTGCAGCTG 
CGTGAGCTGG CCCAGCGCGG GAGCGCCGCC TGCTGGCTGC CGCTCGGCCG CCGCATCCAC 
ATGGACGACA CGGGCCTCAC GGTGCTGCGA ATCCTCTCGC AGCGCAGCAA CGACGAGGTG 
GCCAAGGAGT TCGTGAAGCT CAAGTCGGAC ACGCGCTCCG CCGAGGAGGG CGGTGCCGCG 
CCTGCGCCTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UNC13A ( XM_011527810.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526112.1 Homo sapiens unc-13 homolog A (UNC13A), transcript variant X2, mRNA.

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CloneID	OHu65310
Clone ID Related Accession (Same CDS sequence)	XM_011527810.2
Accession Version	XM_011527810.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5082bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein unc-13 homolog A isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527810.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCTGC TTTGCGTTGG AGAGAAATTC AACACGTACG TGACCCTGAA AGTGCAGAAT 
GTCAAGAGCA CGACCATCGC GGTGCGGGGC AGCCAGCCCA GCTGGGAGCA GGATTTCATG 
TTCGAGATTA ACCGTCTGGA TTTGGGACTG ACGGTGGAGG TGTGGAATAA GGGTCTCATC 
TGGGACACAA TGGTGGGCAC TGTGTGGATC CCACTGAGGA CCATCCGCCA GTCCAATGAG 
GAGGGCCCTG GAGAGTGGCT GACGCTGGAC TCCCAGGTCA TCATGGCAGA CAGTGAGATC 
TGTGGCACCA AGGACCCCAC CTTCCACCGC ATCCTCCTGG ACACGCGCTT TGAGCTACCC 
TTAGACATTC CTGAAGAGGA GGCTCGCTAC TGGGCCAAGA AGCTGGAGCA GCTCAATGCT 
ATGCGGGACC AGGATGAATA TTCGTTCCAA GATGAGCAAG ACAAGCCTCT GCCTGTCCCC 
AGCAACCAGT GCTGCAACTG GAATTATTTT GGCTGGGGTG AGCAGCACAA CGATGACCCC 
GACAGTGCAG TGGATGATCG TGACAGTGAC TACCGCAGTG AAACGAGCAA CAGCATCCCG 
CCGCCCTATT ATACTACGTC ACAACCCAAC GCCTCAGTCC ACCAATATTC TGTTCGCCCA 
CCACCCCTGG GCTCCCGGGA GTCCTACAGT GACTCCATGC ACAGTTACGA GGAGTTCTCT 
GAGCCACAAG CCCTCAGCCC CACGGGTAGC AGCCGCTATG CCTCTTCCGG GGAGCTGAGC 
CAGGGAAGCT CTCAGCTGAG CGAGGACTTC GACCCTGACG AGCACAGCCT GCAGGGCTCC 
GACATGGAGG ATGAGCGGGA CCGGGACTCC TACCACTCCT GCCACAGCTC GGTCAGCTAC 
CACAAAGACT CGCCTCGCTG GGACCAGGAT GAGGAAGAGC TGGAGGAGGA CCTGGAGGAC 
TTCCTGGAGG AGGAGGAGCT GCCTGAAGAT GAGGAGGAGC TGGAGGAGGA GGAGGAGGAG 
GTGCCTGACG ATTTGGGCAG CTATGCCCAG CGTGAAGACG TAGCTGTGGC TGAGCCCAAA 
GACTTCAAAC GCATCAGCCT CCCGCCAGCT GCCCCAGGGA AGGAGGACAA GGCCCCAGTG 
GCACCCACCG AGGCCCCCGA CATGGCCAAG GTGGCCCCCA AGCCAGCCAC GCCCGACAAG 
GTGCCTGCAG CTGAGCAGAT CCCTGAGGCT GAGCCACCCA AGGACGAGGA GAGTTTCAGG 
CCGAGAGAGG ATGAGGAAGG CCAGGAGGGG CAGGACTCCA TGTCCAGGGC CAAGGCCAAC 
TGGCTGCGTG CCTTCAACAA GGTGCGGATG CAGCTGCAGG AGGCCCGGGG AGAAGGAGAG 
ATGTCTAAAT CCCTATGGTT CAAAGGCGGC CCAGGGGGCG GTCTCATCAT CATCGACAGC 
ATGCCAGACA TCCGCAAGAG GAAACCTATC CCACTCGTGA GCGACTTGGC CATGTCCCTG 
GTCCAGTCCA GGAAAGCGGG CATCACCTCG GCCTTGGCCT CCAGCACGTT GAACAACGAG 
GAGCTGAAAA ACCACGTTTA CAAGAAGACC CTGCAAGCCT TAATCTACCC CATCTCGTGC 
ACGACGCCAC ACAACTTCGA AGTGTGGACG GCCACCACGC CCACCTACTG CTACGAGTGC 
GAGGGGCTGC TGTGGGGCAT CGCGAGGCAG GGCATGCGCT GCACCGAGTG CGGTGTCAAG 
TGCCACGAGA AGTGCCAGGA CCTGCTCAAC GCCGACTGCC TGCAGCGGGC TGCGGAGAAG 
AGCTCCAAGC ACGGGGCGGA GGACCGGACA CAGAACATCA TCATGGTGCT CAAGGACCGC 
ATGAAGATCC GGGAGCGCAA CAAGCCCGAG ATCTTCGAGC TCATCCAGGA GATCTTCGCG 
GTGACCAAGA CGGCGCACAC GCAGCAGATG AAGGCGGTCA AGCAGAGCGT GCTGGACGGC 
ACGTCCAAGT GGTCCGCCAA GATCAGCATC ACCGTGGTCT GCGCCCAGGG CTTGCAGGCA 
AAGGACAAGA CAGGATCCAG TGACCCCTAT GTCACCGTCC AGGTCGGGAA GACCAAGAAA 
CGGACAAAAA CCATCTATGG GAACCTCAAC CCGGTGTGGG AGGAGAATTT CCACTTTGAA 
TGTCACAATT CCTCCGACCG CATCAAGGTG CGCGTCTGGG ACGAGGATGA CGACATCAAA 
TCCCGCGTGA AACAGAGGTT CAAGAGGGAA TCTGACGATT TCCTGGGGCA GACGATCATT 
GAGGTGCGGA CGCTCAGCGG CGAGATGGAC GTGTGGTACA ACCTGGACAA GCGAACTGAC 
AAATCTGCCG TGTCGGGTGC CATCCGGCTC CACATCAGTG TGGAGATCAA AGGCGAGGAG 
AAGGTGGCCC CGTACCATGT CCAGTACACC TGTCTGCATG AGAACCTGTT CCACTTCGTG 
ACCGACGTGC AGAACAATGG GGTCGTGAAG ATCCCAGATG CCAAGGGTGA CGATGCCTGG 
AAGGTTTACT ACGATGAGAC AGCCCAGGAG ATTGTGGACG AGTTTGCCAT GCGCTACGGC 
GTCGAGTCCA TCTACCAAGC CATGACCCAC TTTGCCTGCC TCTCCTCCAA GTATATGTGC 
CCAGGGGTGC CTGCCGTCAT GAGCACCCTG CTCGCCAACA TCAATGCCTA CTACGCACAC 
ACCACCGCCT CCACCAACGT GTCTGCCTCC GACCGCTTCG CCGCCTCCAA CTTTGGGAAA 
GAGCGCTTCG TGAAACTCCT GGACCAGCTG CATAACTCCC TGCGGATTGA CCTCTCCATG 
TACCGGAATA ACTTCCCAGC CAGCAGCCCG GAGAGACTCC AGGACCTCAA ATCCACTGTG 
GACCTTCTCA CCAGCATCAC CTTCTTTCGG ATGAAGGTAC AAGAACTCCA GAGCCCGCCC 
CGAGCCAGCC AGGTGGTAAA GGACTGTGTG AAAGCCTGCC TTAATTCTAC CTACGAGTAC 
ATCTTCAATA ACTGCCATGA ACTGTACAGC CGGGAGTACC AGACAGACCC GGCCAAGAAG 
GGGGAAGTTC TCCCAGAGGA ACAGGGGCCC AGCATCAAGA ACCTCGACTT CTGGTCCAAG 
CTGATTACCC TCATAGTGTC CATCATTGAG GAAGACAAGA ATTCCTACAC TCCCTGCCTC 
AACCAGTTTC CCCAGGAGCT GAATGTGGGT AAAATCAGCG CTGAAGTGAT GTGGAATCTG 
TTTGCCCAAG ACATGAAGTA CGCCATGGAG GAGCACGACA AGCATCGTCT ATGCAAGAGT 
GCCGACTACA TGAACCTCCA CTTCAAGGTG AAATGGCTCT ACAATGAGTA TGTGACGGAA 
CTTCCCGCCT TCAAGGACCG CGTGCCTGAG TACCCTGCAT GGTTTGAACC CTTCGTCATC 
CAGTGGCTGG ATGAGAATGA GGAGGTGTCC CGGGATTTCC TGCACGGTGC CCTGGAGCGA 
GACAAGAAGG ATGGGTTCCA GCAGACCTCA GAGCATGCCC TATTCTCCTG CTCCGTGGTG 
GATGTTTTCT CCCAACTCAA CCAGAGCTTT GAAATCATCA AGAAACTCGA GTGTCCCGAC 
CCTCAGATCG TGGGGCACTA CATGAGGCGC TTTGCCAAGA CCATCAGTAA TGTGCTCCTC 
CAGTATGCAG ACATCATCTC CAAGGACTTT GCCTCCTACT GCTCCAAGGA GAAGGAGAAA 
GTGCCCTGCA TTCTCATGAA TAACACTCAA CAGCTACGAG TTCAGCTGGA GAAGATGTTC 
GAAGCCATGG GAGGAAAGGA GCTGGATGCT GAAGCCAGTG ACATCCTGAA GGAGCTTCAG 
GTGAAACTCA ATAACGTCTT GGATGAGCTC AGCCGGGTGT TTGCTACCAG CTTCCAGCCG 
CACATTGAAG AGTGTGTCAA ACAGATGGGT GACATCCTTA GCCAGGTTAA GGGCACAGGC 
AATGTGCCAG CCAGTGCCTG CAGCAGCGTG GCCCAGGACG CGGACAATGT GTTGCAGCCC 
ATCATGGACC TGCTGGACAG CAACCTGACC CTCTTTGCCA AAATCTGTGA GAAGACTGTG 
CTGAAGCGAG TGCTGAAGGA GCTGTGGAAG CTGGTTATGA ACACCATGGA GAAAACCATC 
GTCCTGCCGC CCCTCACTGA CCAGACGATG ATCGGGAACC TCTTGAGAAA ACATGGCAAG 
GGATTAGAAA AGGGCAGGGT GAAATTGCCA AGCCACTCAG ACGGAACCCA GATGATCTTC 
AATGCAGCCA AGGAGCTGGG TCAGCTGTCC AAACTCAAGG ATCACATGGT ACGAGAAGAA 
GCCAAGAGCT TGACCCCAAA GCAGTGCGCG GTTGTTGAGT TGGCCCTGGA CACCATCAAG 
CAATATTTCC ACGCGGGTGG CGTGGGCCTC AAGAAGACCT TCCTGGAGAA GAGCCCGGAC 
CTGCAATCCT TGCGCTATGC CCTGTCGCTC TACACGCAGG CCACCGACCT GCTAATCAAG 
ACCTTTGTAC AGACGCAATC GGCCCAGGGC TTGGGTGTAG AAGACCCTGT GGGTGAAGTC 
TCTGTCCATG TTGAGCTGTT CACTCATCCA GGAACTGGGG AACACAAGGT CACAGTGAAA 
GTGGTGGCTG CCAATGACCT CAAGTGGCAG ACTTCTGGCA TCTTCCGGCC GTTCATCGAG 
GTCAACATCA TTGGGCCCCA GCTCAGCGAC AAGAAACGCA AGTTTGCGAC CAAATCCAAG 
AACAATAGCT GGGCTCCCAA GTACAATGAG AGCTTCCAGT TCACGCTGAG CGCCGACGCG 
GGTCCCGAGT GCTATGAGCT GCAGGTGTGC GTCAAGGACT ACTGCTTCGC GCGCGAGGAC 
CGCACGGTGG GGCTGGCCGT GCTGCAGCTG CGTGAGCTGG CCCAGCGCGG GAGCGCCGCC 
TGCTGGCTGC CGCTCGGCCG CCGCATCCAC ATGGACGACA CGGGCCTCAC GGTGCTGCGA 
ATCCTCTCGC AGCGCAGCAA CGACGAGGTG GCCAAGGAGT TCGTGAAGCT CAAGTCGGAC 
ACGCGCTCCG CCGAGGAGGG CGGTGCCGCG CCTGCGCCTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526112.1
CDS	146..5227
Translation	MSLLCVGEKFNTYVTLKVQNVKSTTIAVRGSQPSWEQDFMFEINRLDLGLTVEVWNKGLIWDTMVGTVWIPLRTIRQSNEEGPGEWLTLDSQVIMADSEICGTKDPTFHRILLDTRFELPLDIPEEEARYWAKKLEQLNAMRDQDEYSFQDEQDKPLPVPSNQCCNWNYFGWGEQHNDDPDSAVDDRDSDYRSETSNSIPPPYYTTSQPNASVHQYSVRPPPLGSRESYSDSMHSYEEFSEPQALSPTGSSRYASSGELSQGSSQLSEDFDPDEHSLQGSDMEDERDRDSYHSCHSSVSYHKDSPRWDQDEEELEEDLEDFLEEEELPEDEEELEEEEEEVPDDLGSYAQREDVAVAEPKDFKRISLPPAAPGKEDKAPVAPTEAPDMAKVAPKPATPDKVPAAEQIPEAEPPKDEESFRPREDEEGQEGQDSMSRAKANWLRAFNKVRMQLQEARGEGEMSKSLWFKGGPGGGLIIIDSMPDIRKRKPIPLVSDLAMSLVQSRKAGITSALASSTLNNEELKNHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDRTQNIIMVLKDRMKIRERNKPEIFELIQEIFAVTKTAHTQQMKAVKQSVLDGTSKWSAKISITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHFECHNSSDRIKVRVWDEDDDIKSRVKQRFKRESDDFLGQTIIEVRTLSGEMDVWYNLDKRTDKSAVSGAIRLHISVEIKGEEKVAPYHVQYTCLHENLFHFVTDVQNNGVVKIPDAKGDDAWKVYYDETAQEIVDEFAMRYGVESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHELYSREYQTDPAKKGEVLPEEQGPSIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVGKISAEVMWNLFAQDMKYAMEEHDKHRLCKSADYMNLHFKVKWLYNEYVTELPAFKDRVPEYPAWFEPFVIQWLDENEEVSRDFLHGALERDKKDGFQQTSEHALFSCSVVDVFSQLNQSFEIIKKLECPDPQIVGHYMRRFAKTISNVLLQYADIISKDFASYCSKEKEKVPCILMNNTQQLRVQLEKMFEAMGGKELDAEASDILKELQVKLNNVLDELSRVFATSFQPHIEECVKQMGDILSQVKGTGNVPASACSSVAQDADNVLQPIMDLLDSNLTLFAKICEKTVLKRVLKELWKLVMNTMEKTIVLPPLTDQTMIGNLLRKHGKGLEKGRVKLPSHSDGTQMIFNAAKELGQLSKLKDHMVREEAKSLTPKQCAVVELALDTIKQYFHAGGVGLKKTFLEKSPDLQSLRYALSLYTQATDLLIKTFVQTQSAQGLGVEDPVGEVSVHVELFTHPGTGEHKVTVKVVAANDLKWQTSGIFRPFIEVNIIGPQLSDKKRKFATKSKNNSWAPKYNESFQFTLSADAGPECYELQVCVKDYCFAREDRTVGLAVLQLRELAQRGSAACWLPLGRRIHMDDTGLTVLRILSQRSNDEVAKEFVKLKSDTRSAEEGGAAPAP

Target ORF information:

RefSeq Version	XM_011527810.2
Organism	Homo sapiens(human)
Definition	Homo sapiens unc-13 homolog A (UNC13A), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527810.2

ORF Insert Sequence:

ATGTCTCTGC TTTGCGTTGG AGAGAAATTC AACACGTACG TGACCCTGAA AGTGCAGAAT 
GTCAAGAGCA CGACCATCGC GGTGCGGGGC AGCCAGCCCA GCTGGGAGCA GGATTTCATG 
TTCGAGATTA ACCGTCTGGA TTTGGGACTG ACGGTGGAGG TGTGGAATAA GGGTCTCATC 
TGGGACACAA TGGTGGGCAC TGTGTGGATC CCACTGAGGA CCATCCGCCA GTCCAATGAG 
GAGGGCCCTG GAGAGTGGCT GACGCTGGAC TCCCAGGTCA TCATGGCAGA CAGTGAGATC 
TGTGGCACCA AGGACCCCAC CTTCCACCGC ATCCTCCTGG ACACGCGCTT TGAGCTACCC 
TTAGACATTC CTGAAGAGGA GGCTCGCTAC TGGGCCAAGA AGCTGGAGCA GCTCAATGCT 
ATGCGGGACC AGGATGAATA TTCGTTCCAA GATGAGCAAG ACAAGCCTCT GCCTGTCCCC 
AGCAACCAGT GCTGCAACTG GAATTATTTT GGCTGGGGTG AGCAGCACAA CGATGACCCC 
GACAGTGCAG TGGATGATCG TGACAGTGAC TACCGCAGTG AAACGAGCAA CAGCATCCCG 
CCGCCCTATT ATACTACGTC ACAACCCAAC GCCTCAGTCC ACCAATATTC TGTTCGCCCA 
CCACCCCTGG GCTCCCGGGA GTCCTACAGT GACTCCATGC ACAGTTACGA GGAGTTCTCT 
GAGCCACAAG CCCTCAGCCC CACGGGTAGC AGCCGCTATG CCTCTTCCGG GGAGCTGAGC 
CAGGGAAGCT CTCAGCTGAG CGAGGACTTC GACCCTGACG AGCACAGCCT GCAGGGCTCC 
GACATGGAGG ATGAGCGGGA CCGGGACTCC TACCACTCCT GCCACAGCTC GGTCAGCTAC 
CACAAAGACT CGCCTCGCTG GGACCAGGAT GAGGAAGAGC TGGAGGAGGA CCTGGAGGAC 
TTCCTGGAGG AGGAGGAGCT GCCTGAAGAT GAGGAGGAGC TGGAGGAGGA GGAGGAGGAG 
GTGCCTGACG ATTTGGGCAG CTATGCCCAG CGTGAAGACG TAGCTGTGGC TGAGCCCAAA 
GACTTCAAAC GCATCAGCCT CCCGCCAGCT GCCCCAGGGA AGGAGGACAA GGCCCCAGTG 
GCACCCACCG AGGCCCCCGA CATGGCCAAG GTGGCCCCCA AGCCAGCCAC GCCCGACAAG 
GTGCCTGCAG CTGAGCAGAT CCCTGAGGCT GAGCCACCCA AGGACGAGGA GAGTTTCAGG 
CCGAGAGAGG ATGAGGAAGG CCAGGAGGGG CAGGACTCCA TGTCCAGGGC CAAGGCCAAC 
TGGCTGCGTG CCTTCAACAA GGTGCGGATG CAGCTGCAGG AGGCCCGGGG AGAAGGAGAG 
ATGTCTAAAT CCCTATGGTT CAAAGGCGGC CCAGGGGGCG GTCTCATCAT CATCGACAGC 
ATGCCAGACA TCCGCAAGAG GAAACCTATC CCACTCGTGA GCGACTTGGC CATGTCCCTG 
GTCCAGTCCA GGAAAGCGGG CATCACCTCG GCCTTGGCCT CCAGCACGTT GAACAACGAG 
GAGCTGAAAA ACCACGTTTA CAAGAAGACC CTGCAAGCCT TAATCTACCC CATCTCGTGC 
ACGACGCCAC ACAACTTCGA AGTGTGGACG GCCACCACGC CCACCTACTG CTACGAGTGC 
GAGGGGCTGC TGTGGGGCAT CGCGAGGCAG GGCATGCGCT GCACCGAGTG CGGTGTCAAG 
TGCCACGAGA AGTGCCAGGA CCTGCTCAAC GCCGACTGCC TGCAGCGGGC TGCGGAGAAG 
AGCTCCAAGC ACGGGGCGGA GGACCGGACA CAGAACATCA TCATGGTGCT CAAGGACCGC 
ATGAAGATCC GGGAGCGCAA CAAGCCCGAG ATCTTCGAGC TCATCCAGGA GATCTTCGCG 
GTGACCAAGA CGGCGCACAC GCAGCAGATG AAGGCGGTCA AGCAGAGCGT GCTGGACGGC 
ACGTCCAAGT GGTCCGCCAA GATCAGCATC ACCGTGGTCT GCGCCCAGGG CTTGCAGGCA 
AAGGACAAGA CAGGATCCAG TGACCCCTAT GTCACCGTCC AGGTCGGGAA GACCAAGAAA 
CGGACAAAAA CCATCTATGG GAACCTCAAC CCGGTGTGGG AGGAGAATTT CCACTTTGAA 
TGTCACAATT CCTCCGACCG CATCAAGGTG CGCGTCTGGG ACGAGGATGA CGACATCAAA 
TCCCGCGTGA AACAGAGGTT CAAGAGGGAA TCTGACGATT TCCTGGGGCA GACGATCATT 
GAGGTGCGGA CGCTCAGCGG CGAGATGGAC GTGTGGTACA ACCTGGACAA GCGAACTGAC 
AAATCTGCCG TGTCGGGTGC CATCCGGCTC CACATCAGTG TGGAGATCAA AGGCGAGGAG 
AAGGTGGCCC CGTACCATGT CCAGTACACC TGTCTGCATG AGAACCTGTT CCACTTCGTG 
ACCGACGTGC AGAACAATGG GGTCGTGAAG ATCCCAGATG CCAAGGGTGA CGATGCCTGG 
AAGGTTTACT ACGATGAGAC AGCCCAGGAG ATTGTGGACG AGTTTGCCAT GCGCTACGGC 
GTCGAGTCCA TCTACCAAGC CATGACCCAC TTTGCCTGCC TCTCCTCCAA GTATATGTGC 
CCAGGGGTGC CTGCCGTCAT GAGCACCCTG CTCGCCAACA TCAATGCCTA CTACGCACAC 
ACCACCGCCT CCACCAACGT GTCTGCCTCC GACCGCTTCG CCGCCTCCAA CTTTGGGAAA 
GAGCGCTTCG TGAAACTCCT GGACCAGCTG CATAACTCCC TGCGGATTGA CCTCTCCATG 
TACCGGAATA ACTTCCCAGC CAGCAGCCCG GAGAGACTCC AGGACCTCAA ATCCACTGTG 
GACCTTCTCA CCAGCATCAC CTTCTTTCGG ATGAAGGTAC AAGAACTCCA GAGCCCGCCC 
CGAGCCAGCC AGGTGGTAAA GGACTGTGTG AAAGCCTGCC TTAATTCTAC CTACGAGTAC 
ATCTTCAATA ACTGCCATGA ACTGTACAGC CGGGAGTACC AGACAGACCC GGCCAAGAAG 
GGGGAAGTTC TCCCAGAGGA ACAGGGGCCC AGCATCAAGA ACCTCGACTT CTGGTCCAAG 
CTGATTACCC TCATAGTGTC CATCATTGAG GAAGACAAGA ATTCCTACAC TCCCTGCCTC 
AACCAGTTTC CCCAGGAGCT GAATGTGGGT AAAATCAGCG CTGAAGTGAT GTGGAATCTG 
TTTGCCCAAG ACATGAAGTA CGCCATGGAG GAGCACGACA AGCATCGTCT ATGCAAGAGT 
GCCGACTACA TGAACCTCCA CTTCAAGGTG AAATGGCTCT ACAATGAGTA TGTGACGGAA 
CTTCCCGCCT TCAAGGACCG CGTGCCTGAG TACCCTGCAT GGTTTGAACC CTTCGTCATC 
CAGTGGCTGG ATGAGAATGA GGAGGTGTCC CGGGATTTCC TGCACGGTGC CCTGGAGCGA 
GACAAGAAGG ATGGGTTCCA GCAGACCTCA GAGCATGCCC TATTCTCCTG CTCCGTGGTG 
GATGTTTTCT CCCAACTCAA CCAGAGCTTT GAAATCATCA AGAAACTCGA GTGTCCCGAC 
CCTCAGATCG TGGGGCACTA CATGAGGCGC TTTGCCAAGA CCATCAGTAA TGTGCTCCTC 
CAGTATGCAG ACATCATCTC CAAGGACTTT GCCTCCTACT GCTCCAAGGA GAAGGAGAAA 
GTGCCCTGCA TTCTCATGAA TAACACTCAA CAGCTACGAG TTCAGCTGGA GAAGATGTTC 
GAAGCCATGG GAGGAAAGGA GCTGGATGCT GAAGCCAGTG ACATCCTGAA GGAGCTTCAG 
GTGAAACTCA ATAACGTCTT GGATGAGCTC AGCCGGGTGT TTGCTACCAG CTTCCAGCCG 
CACATTGAAG AGTGTGTCAA ACAGATGGGT GACATCCTTA GCCAGGTTAA GGGCACAGGC 
AATGTGCCAG CCAGTGCCTG CAGCAGCGTG GCCCAGGACG CGGACAATGT GTTGCAGCCC 
ATCATGGACC TGCTGGACAG CAACCTGACC CTCTTTGCCA AAATCTGTGA GAAGACTGTG 
CTGAAGCGAG TGCTGAAGGA GCTGTGGAAG CTGGTTATGA ACACCATGGA GAAAACCATC 
GTCCTGCCGC CCCTCACTGA CCAGACGATG ATCGGGAACC TCTTGAGAAA ACATGGCAAG 
GGATTAGAAA AGGGCAGGGT GAAATTGCCA AGCCACTCAG ACGGAACCCA GATGATCTTC 
AATGCAGCCA AGGAGCTGGG TCAGCTGTCC AAACTCAAGG ATCACATGGT ACGAGAAGAA 
GCCAAGAGCT TGACCCCAAA GCAGTGCGCG GTTGTTGAGT TGGCCCTGGA CACCATCAAG 
CAATATTTCC ACGCGGGTGG CGTGGGCCTC AAGAAGACCT TCCTGGAGAA GAGCCCGGAC 
CTGCAATCCT TGCGCTATGC CCTGTCGCTC TACACGCAGG CCACCGACCT GCTAATCAAG 
ACCTTTGTAC AGACGCAATC GGCCCAGGGC TTGGGTGTAG AAGACCCTGT GGGTGAAGTC 
TCTGTCCATG TTGAGCTGTT CACTCATCCA GGAACTGGGG AACACAAGGT CACAGTGAAA 
GTGGTGGCTG CCAATGACCT CAAGTGGCAG ACTTCTGGCA TCTTCCGGCC GTTCATCGAG 
GTCAACATCA TTGGGCCCCA GCTCAGCGAC AAGAAACGCA AGTTTGCGAC CAAATCCAAG 
AACAATAGCT GGGCTCCCAA GTACAATGAG AGCTTCCAGT TCACGCTGAG CGCCGACGCG 
GGTCCCGAGT GCTATGAGCT GCAGGTGTGC GTCAAGGACT ACTGCTTCGC GCGCGAGGAC 
CGCACGGTGG GGCTGGCCGT GCTGCAGCTG CGTGAGCTGG CCCAGCGCGG GAGCGCCGCC 
TGCTGGCTGC CGCTCGGCCG CCGCATCCAC ATGGACGACA CGGGCCTCAC GGTGCTGCGA 
ATCCTCTCGC AGCGCAGCAA CGACGAGGTG GCCAAGGAGT TCGTGAAGCT CAAGTCGGAC 
ACGCGCTCCG CCGAGGAGGG CGGTGCCGCG CCTGCGCCTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UNC13A ( XM_011527811.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526113.1 Homo sapiens unc-13 homolog A (UNC13A), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu65311
Clone ID Related Accession (Same CDS sequence)	XM_011527811.2
Accession Version	XM_011527811.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5043bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein unc-13 homolog A isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527811.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCTGC TTTGCGTTGG AGTCAAAAAA GCCAAGTTTG ATGGTGCCCA AGAGAAATTC 
AACACGTACG TGACCCTGAA AGTGCAGAAT GTCAAGAGCA CGACCATCGC GGTGCGGGGC 
AGCCAGCCCA GCTGGGAGCA GGATTTCATG TTCGAGATTA ACCGTCTGGA TTTGGGACTG 
ACGGTGGAGG TGTGGAATAA GGGTCTCATC TGGGACACAA TGGTGGGCAC TGTGTGGATC 
CCACTGAGGA CCATCCGCCA GTCCAATGAG GAGGGCCCTG GAGAGTGGCT GACGCTGGAC 
TCCCAGGTCA TCATGGCAGA CAGTGAGATC TGTGGCACCA AGGACCCCAC CTTCCACCGC 
ATCCTCCTGG ACACGCGCTT TGAGCTACCC TTAGACATTC CTGAAGAGGA GGCTCGCTAC 
TGGGCCAAGA AGCTGGAGCA GCTCAATGCT ATGCGGGACC AGGATGAATA TTCGTTCCAA 
GATGAGCAAG ACAAGCCTCT GCCTGTCCCC AGCAACCAGT GCTGCAACTG GAATTATTTT 
GGCTGGGGTG AGCAGCACAA CGATGACCCC GACAGTGCAG TGGATGATCG TGACAGTGAC 
TACCGCAGTG AAACGAGCAA CAGCATCCCG CCGCCCTATT ATACTACGTC ACAACCCAAC 
GCCTCAGTCC ACCAATATTC TGTTCGCCCA CCACCCCTGG GCTCCCGGGA GTCCTACAGT 
GACTCCATGC ACAGTTACGA GGAGTTCTCT GAGCCACAAG CCCTCAGCCC CACGGGTAGC 
AGCCGCTATG CCTCTTCCGG GGAGCTGAGC CAGGGAAGCT CTCAGCTGAG CGAGGACTTC 
GACCCTGACG AGCACAGCCT GCAGGGCTCC GACATGGAGG ATGAGCGGGA CCGGGACTCC 
TACCACTCCT GCCACAGCTC GGTCAGCTAC CACAAAGACT CGCCTCGCTG GGACCAGGAT 
GAGGAAGAGC TGGAGGAGGA CCTGGAGGAC TTCCTGGAGG AGGAGGAGCT GCCTGAAGAT 
GAGGAGGAGC TGGAGGAGGA GGAGGAGGAG GTGCCTGACG ATTTGGGCAG CTATGCCCAG 
CGTGAAGACG TAGCTGTGGC TGAGCCCAAA GACTTCAAAC GCATCAGCCT CCCGCCAGCT 
GCCCCAGGGA AGGAGGACAA GGCCCCAGTG GCACCCACCG AGGCCCCCGA CATGGCCAAG 
GTGGCCCCCA AGCCAGCCAC GCCCGACAAG GTGCCTGCAG CTGAGCAGAT CCCTGAGGCT 
GAGCCACCCA AGGACGAGGA GAGTTTCAGG CCGAGAGAGG ATGAGGAAGG CCAGGAGGGG 
CAGGACTCCA TGTCCAGGGC CAAGGCCAAC TGGCTGCGTG CCTTCAACAA GGTGCGGATG 
CAGCTGCAGG AGGCCCGGGG AGAAGGAGAG ATGTCTAAAT CCCTATGGTT CAAAGGCGGC 
CCAGGGGGCG GTCTCATCAT CATCGACAGC ATGCCAGACA TCCGCAAGAG GAAACCTATC 
CCACTCGTGA GCGACTTGGC CATGTCCCTG GTCCAGTCCA GGAAAGCGGG CATCACCTCG 
GCCTTGGCCT CCAGCACGTT GAACAACGAG GAGCTGAAAA ACCACGTTTA CAAGAAGACC 
CTGCAAGCCT TAATCTACCC CATCTCGTGC ACGACGCCAC ACAACTTCGA AGTGTGGACG 
GCCACCACGC CCACCTACTG CTACGAGTGC GAGGGGCTGC TGTGGGGCAT CGCGAGGCAG 
GGCATGCGCT GCACCGAGTG CGGTGTCAAG TGCCACGAGA AGTGCCAGGA CCTGCTCAAC 
GCCGACTGCC TGCAGCGGGC TGCGGAGAAG AGCTCCAAGC ACGGGGCGGA GGACCGGACA 
CAGAACATCA TCATGGTGCT CAAGGACCGC ATGAAGATCC GGGAGCGCAA CAAGCCCGAG 
ATCTTCGAGC TCATCCAGGA GATCTTCGCG GTGACCAAGA CGGCGCACAC GCAGCAGATG 
AAGGCGGTCA AGCAGAGCGT GCTGGACGGC ACGTCCAAGT GGTCCGCCAA GATCAGCATC 
ACCGTGGTCT GCGCCCAGGG CTTGCAGGCA AAGGACAAGA CAGGATCCAG TGACCCCTAT 
GTCACCGTCC AGGTCGGGAA GACCAAGAAA CGGACAAAAA CCATCTATGG GAACCTCAAC 
CCGGTGTGGG AGGAGAATTT CCACTTTGAA TGTCACAATT CCTCCGACCG CATCAAGGTG 
CGCGTCTGGG ACGAGGATGA CGACATCAAA TCCCGCGTGA AACAGAGGTT CAAGAGGGAA 
TCTGACGATT TCCTGGGGCA GACGATCATT GAGGTGCGGA CGCTCAGCGG CGAGATGGAC 
GTGTGGTACA ACCTGGACAA GCGAACTGAC AAATCTGCCG TGTCGGGTGC CATCCGGCTC 
CACATCAGTG TGGAGATCAA AGGCGAGGAG AAGGTGGCCC CGTACCATGT CCAGTACACC 
TGTCTGCATG AGAACCTGTT CCACTTCGTG ACCGACGTGC AGAACAATGG GGTCGTGAAG 
ATCCCAGATG CCAAGGGTGA CGATGCCTGG AAGGTTTACT ACGATGAGAC AGCCCAGGAG 
ATTGTGGACG AGTTTGCCAT GCGCTACGGC GTCGAGTCCA TCTACCAAGC CATGACCCAC 
TTTGCCTGCC TCTCCTCCAA GTATATGTGC CCAGGGGTGC CTGCCGTCAT GAGCACCCTG 
CTCGCCAACA TCAATGCCTA CTACGCACAC ACCACCGCCT CCACCAACGT GTCTGCCTCC 
GACCGCTTCG CCGCCTCCAA CTTTGGGAAA GAGCGCTTCG TGAAACTCCT GGACCAGCTG 
CATAACTCCC TGCGGATTGA CCTCTCCATG TACCGGAATA ACTTCCCAGC CAGCAGCCCG 
GAGAGACTCC AGGACCTCAA ATCCACTGTG GACCTTCTCA CCAGCATCAC CTTCTTTCGG 
ATGAAGGTAC AAGAACTCCA GAGCCCGCCC CGAGCCAGCC AGGTGGTAAA GGACTGTGTG 
AAAGCCTGCC TTAATTCTAC CTACGAGTAC ATCTTCAATA ACTGCCATGA ACTGTACAGC 
CGGGAGTACC AGACAGACCC GGCCAAGAAG GGGGAAGTTC TCCCAGAGGA ACAGGGGCCC 
AGCATCAAGA ACCTCGACTT CTGGTCCAAG CTGATTACCC TCATAGTGTC CATCATTGAG 
GAAGACAAGA ATTCCTACAC TCCCTGCCTC AACCAGTTTC CCCAGGAGCT GAATGTGGGT 
AAAATCAGCG CTGAAGTGAT GTGGAATCTG TTTGCCCAAG ACATGAAGTA CGCCATGGAG 
GAGCACGACA AGCATCGTCT ATGCAAGAGT GCCGACTACA TGAACCTCCA CTTCAAGGTG 
AAATGGCTCT ACAATGAGTA TGTGACGGAA CTTCCCGCCT TCAAGGACCG CGTGCCTGAG 
TACCCTGCAT GGTTTGAACC CTTCGTCATC CAGTGGCTGG ATGAGAATGA GGAGGTGTCC 
CGGGATTTCC TGCACGGTGC CCTGGAGCGA GACAAGAAGG ATGGGTTCCA GCAGACCTCA 
GAGCATGCCC TATTCTCCTG CTCCGTGGTG GATGTTTTCT CCCAACTCAA CCAGAGCTTT 
GAAATCATCA AGAAACTCGA GTGTCCCGAC CCTCAGATCG TGGGGCACTA CATGAGGCGC 
TTTGCCAAGA CCATCAGTAA TGTGCTCCTC CAGTATGCAG ACATCATCTC CAAGGACTTT 
GCCTCCTACT GCTCCAAGGA GAAGGAGAAA GTGCCCTGCA TTCTCATGAA TAACACTCAA 
CAGCTACGAG TTCAGCTGGA GAAGATGTTC GAAGCCATGG GAGGAAAGGA GCTGGATGCT 
GAAGCCAGTG ACATCCTGAA GGAGCTTCAG GTGAAACTCA ATAACGTCTT GGATGAGCTC 
AGCCGGGTGT TTGCTACCAG CTTCCAGCCG CACATTGAAG AGTGTGTCAA ACAGATGGGT 
GACATCCTTA GCCAGGTTAA GGGCACAGGC AATGTGCCAG CCAGTGCCTG CAGCAGCGTG 
GCCCAGGACG CGGACAATGT GTTGCAGCCC ATCATGGACC TGCTGGACAG CAACCTGACC 
CTCTTTGCCA AAATCTGTGA GAAGACTGTG CTGAAGCGAG TGCTGAAGGA GCTGTGGAAG 
CTGGTTATGA ACACCATGGA GAAAACCATC GTCCTGCCGC CCCTCACTGA CCAGACGATG 
ATCGGAACCC AGATGATCTT CAATGCAGCC AAGGAGCTGG GTCAGCTGTC CAAACTCAAG 
GATCACATGG TACGAGAAGA AGCCAAGAGC TTGACCCCAA AGCAGTGCGC GGTTGTTGAG 
TTGGCCCTGG ACACCATCAA GCAATATTTC CACGCGGGTG GCGTGGGCCT CAAGAAGACC 
TTCCTGGAGA AGAGCCCGGA CCTGCAATCC TTGCGCTATG CCCTGTCGCT CTACACGCAG 
GCCACCGACC TGCTAATCAA GACCTTTGTA CAGACGCAAT CGGCCCAGGG CTTGGGTGTA 
GAAGACCCTG TGGGTGAAGT CTCTGTCCAT GTTGAGCTGT TCACTCATCC AGGAACTGGG 
GAACACAAGG TCACAGTGAA AGTGGTGGCT GCCAATGACC TCAAGTGGCA GACTTCTGGC 
ATCTTCCGGC CGTTCATCGA GGTCAACATC ATTGGGCCCC AGCTCAGCGA CAAGAAACGC 
AAGTTTGCGA CCAAATCCAA GAACAATAGC TGGGCTCCCA AGTACAATGA GAGCTTCCAG 
TTCACGCTGA GCGCCGACGC GGGTCCCGAG TGCTATGAGC TGCAGGTGTG CGTCAAGGAC 
TACTGCTTCG CGCGCGAGGA CCGCACGGTG GGGCTGGCCG TGCTGCAGCT GCGTGAGCTG 
GCCCAGCGCG GGAGCGCCGC CTGCTGGCTG CCGCTCGGCC GCCGCATCCA CATGGACGAC 
ACGGGCCTCA CGGTGCTGCG AATCCTCTCG CAGCGCAGCA ACGACGAGGT GGCCAAGGAG 
TTCGTGAAGC TCAAGTCGGA CACGCGCTCC GCCGAGGAGG GCGGTGCCGC GCCTGCGCCT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526113.1
CDS	146..5188
Translation	MSLLCVGVKKAKFDGAQEKFNTYVTLKVQNVKSTTIAVRGSQPSWEQDFMFEINRLDLGLTVEVWNKGLIWDTMVGTVWIPLRTIRQSNEEGPGEWLTLDSQVIMADSEICGTKDPTFHRILLDTRFELPLDIPEEEARYWAKKLEQLNAMRDQDEYSFQDEQDKPLPVPSNQCCNWNYFGWGEQHNDDPDSAVDDRDSDYRSETSNSIPPPYYTTSQPNASVHQYSVRPPPLGSRESYSDSMHSYEEFSEPQALSPTGSSRYASSGELSQGSSQLSEDFDPDEHSLQGSDMEDERDRDSYHSCHSSVSYHKDSPRWDQDEEELEEDLEDFLEEEELPEDEEELEEEEEEVPDDLGSYAQREDVAVAEPKDFKRISLPPAAPGKEDKAPVAPTEAPDMAKVAPKPATPDKVPAAEQIPEAEPPKDEESFRPREDEEGQEGQDSMSRAKANWLRAFNKVRMQLQEARGEGEMSKSLWFKGGPGGGLIIIDSMPDIRKRKPIPLVSDLAMSLVQSRKAGITSALASSTLNNEELKNHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDRTQNIIMVLKDRMKIRERNKPEIFELIQEIFAVTKTAHTQQMKAVKQSVLDGTSKWSAKISITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHFECHNSSDRIKVRVWDEDDDIKSRVKQRFKRESDDFLGQTIIEVRTLSGEMDVWYNLDKRTDKSAVSGAIRLHISVEIKGEEKVAPYHVQYTCLHENLFHFVTDVQNNGVVKIPDAKGDDAWKVYYDETAQEIVDEFAMRYGVESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHELYSREYQTDPAKKGEVLPEEQGPSIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVGKISAEVMWNLFAQDMKYAMEEHDKHRLCKSADYMNLHFKVKWLYNEYVTELPAFKDRVPEYPAWFEPFVIQWLDENEEVSRDFLHGALERDKKDGFQQTSEHALFSCSVVDVFSQLNQSFEIIKKLECPDPQIVGHYMRRFAKTISNVLLQYADIISKDFASYCSKEKEKVPCILMNNTQQLRVQLEKMFEAMGGKELDAEASDILKELQVKLNNVLDELSRVFATSFQPHIEECVKQMGDILSQVKGTGNVPASACSSVAQDADNVLQPIMDLLDSNLTLFAKICEKTVLKRVLKELWKLVMNTMEKTIVLPPLTDQTMIGTQMIFNAAKELGQLSKLKDHMVREEAKSLTPKQCAVVELALDTIKQYFHAGGVGLKKTFLEKSPDLQSLRYALSLYTQATDLLIKTFVQTQSAQGLGVEDPVGEVSVHVELFTHPGTGEHKVTVKVVAANDLKWQTSGIFRPFIEVNIIGPQLSDKKRKFATKSKNNSWAPKYNESFQFTLSADAGPECYELQVCVKDYCFAREDRTVGLAVLQLRELAQRGSAACWLPLGRRIHMDDTGLTVLRILSQRSNDEVAKEFVKLKSDTRSAEEGGAAPAP

Target ORF information:

RefSeq Version	XM_011527811.2
Organism	Homo sapiens(human)
Definition	Homo sapiens unc-13 homolog A (UNC13A), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527811.2

ORF Insert Sequence:

ATGTCTCTGC TTTGCGTTGG AGTCAAAAAA GCCAAGTTTG ATGGTGCCCA AGAGAAATTC 
AACACGTACG TGACCCTGAA AGTGCAGAAT GTCAAGAGCA CGACCATCGC GGTGCGGGGC 
AGCCAGCCCA GCTGGGAGCA GGATTTCATG TTCGAGATTA ACCGTCTGGA TTTGGGACTG 
ACGGTGGAGG TGTGGAATAA GGGTCTCATC TGGGACACAA TGGTGGGCAC TGTGTGGATC 
CCACTGAGGA CCATCCGCCA GTCCAATGAG GAGGGCCCTG GAGAGTGGCT GACGCTGGAC 
TCCCAGGTCA TCATGGCAGA CAGTGAGATC TGTGGCACCA AGGACCCCAC CTTCCACCGC 
ATCCTCCTGG ACACGCGCTT TGAGCTACCC TTAGACATTC CTGAAGAGGA GGCTCGCTAC 
TGGGCCAAGA AGCTGGAGCA GCTCAATGCT ATGCGGGACC AGGATGAATA TTCGTTCCAA 
GATGAGCAAG ACAAGCCTCT GCCTGTCCCC AGCAACCAGT GCTGCAACTG GAATTATTTT 
GGCTGGGGTG AGCAGCACAA CGATGACCCC GACAGTGCAG TGGATGATCG TGACAGTGAC 
TACCGCAGTG AAACGAGCAA CAGCATCCCG CCGCCCTATT ATACTACGTC ACAACCCAAC 
GCCTCAGTCC ACCAATATTC TGTTCGCCCA CCACCCCTGG GCTCCCGGGA GTCCTACAGT 
GACTCCATGC ACAGTTACGA GGAGTTCTCT GAGCCACAAG CCCTCAGCCC CACGGGTAGC 
AGCCGCTATG CCTCTTCCGG GGAGCTGAGC CAGGGAAGCT CTCAGCTGAG CGAGGACTTC 
GACCCTGACG AGCACAGCCT GCAGGGCTCC GACATGGAGG ATGAGCGGGA CCGGGACTCC 
TACCACTCCT GCCACAGCTC GGTCAGCTAC CACAAAGACT CGCCTCGCTG GGACCAGGAT 
GAGGAAGAGC TGGAGGAGGA CCTGGAGGAC TTCCTGGAGG AGGAGGAGCT GCCTGAAGAT 
GAGGAGGAGC TGGAGGAGGA GGAGGAGGAG GTGCCTGACG ATTTGGGCAG CTATGCCCAG 
CGTGAAGACG TAGCTGTGGC TGAGCCCAAA GACTTCAAAC GCATCAGCCT CCCGCCAGCT 
GCCCCAGGGA AGGAGGACAA GGCCCCAGTG GCACCCACCG AGGCCCCCGA CATGGCCAAG 
GTGGCCCCCA AGCCAGCCAC GCCCGACAAG GTGCCTGCAG CTGAGCAGAT CCCTGAGGCT 
GAGCCACCCA AGGACGAGGA GAGTTTCAGG CCGAGAGAGG ATGAGGAAGG CCAGGAGGGG 
CAGGACTCCA TGTCCAGGGC CAAGGCCAAC TGGCTGCGTG CCTTCAACAA GGTGCGGATG 
CAGCTGCAGG AGGCCCGGGG AGAAGGAGAG ATGTCTAAAT CCCTATGGTT CAAAGGCGGC 
CCAGGGGGCG GTCTCATCAT CATCGACAGC ATGCCAGACA TCCGCAAGAG GAAACCTATC 
CCACTCGTGA GCGACTTGGC CATGTCCCTG GTCCAGTCCA GGAAAGCGGG CATCACCTCG 
GCCTTGGCCT CCAGCACGTT GAACAACGAG GAGCTGAAAA ACCACGTTTA CAAGAAGACC 
CTGCAAGCCT TAATCTACCC CATCTCGTGC ACGACGCCAC ACAACTTCGA AGTGTGGACG 
GCCACCACGC CCACCTACTG CTACGAGTGC GAGGGGCTGC TGTGGGGCAT CGCGAGGCAG 
GGCATGCGCT GCACCGAGTG CGGTGTCAAG TGCCACGAGA AGTGCCAGGA CCTGCTCAAC 
GCCGACTGCC TGCAGCGGGC TGCGGAGAAG AGCTCCAAGC ACGGGGCGGA GGACCGGACA 
CAGAACATCA TCATGGTGCT CAAGGACCGC ATGAAGATCC GGGAGCGCAA CAAGCCCGAG 
ATCTTCGAGC TCATCCAGGA GATCTTCGCG GTGACCAAGA CGGCGCACAC GCAGCAGATG 
AAGGCGGTCA AGCAGAGCGT GCTGGACGGC ACGTCCAAGT GGTCCGCCAA GATCAGCATC 
ACCGTGGTCT GCGCCCAGGG CTTGCAGGCA AAGGACAAGA CAGGATCCAG TGACCCCTAT 
GTCACCGTCC AGGTCGGGAA GACCAAGAAA CGGACAAAAA CCATCTATGG GAACCTCAAC 
CCGGTGTGGG AGGAGAATTT CCACTTTGAA TGTCACAATT CCTCCGACCG CATCAAGGTG 
CGCGTCTGGG ACGAGGATGA CGACATCAAA TCCCGCGTGA AACAGAGGTT CAAGAGGGAA 
TCTGACGATT TCCTGGGGCA GACGATCATT GAGGTGCGGA CGCTCAGCGG CGAGATGGAC 
GTGTGGTACA ACCTGGACAA GCGAACTGAC AAATCTGCCG TGTCGGGTGC CATCCGGCTC 
CACATCAGTG TGGAGATCAA AGGCGAGGAG AAGGTGGCCC CGTACCATGT CCAGTACACC 
TGTCTGCATG AGAACCTGTT CCACTTCGTG ACCGACGTGC AGAACAATGG GGTCGTGAAG 
ATCCCAGATG CCAAGGGTGA CGATGCCTGG AAGGTTTACT ACGATGAGAC AGCCCAGGAG 
ATTGTGGACG AGTTTGCCAT GCGCTACGGC GTCGAGTCCA TCTACCAAGC CATGACCCAC 
TTTGCCTGCC TCTCCTCCAA GTATATGTGC CCAGGGGTGC CTGCCGTCAT GAGCACCCTG 
CTCGCCAACA TCAATGCCTA CTACGCACAC ACCACCGCCT CCACCAACGT GTCTGCCTCC 
GACCGCTTCG CCGCCTCCAA CTTTGGGAAA GAGCGCTTCG TGAAACTCCT GGACCAGCTG 
CATAACTCCC TGCGGATTGA CCTCTCCATG TACCGGAATA ACTTCCCAGC CAGCAGCCCG 
GAGAGACTCC AGGACCTCAA ATCCACTGTG GACCTTCTCA CCAGCATCAC CTTCTTTCGG 
ATGAAGGTAC AAGAACTCCA GAGCCCGCCC CGAGCCAGCC AGGTGGTAAA GGACTGTGTG 
AAAGCCTGCC TTAATTCTAC CTACGAGTAC ATCTTCAATA ACTGCCATGA ACTGTACAGC 
CGGGAGTACC AGACAGACCC GGCCAAGAAG GGGGAAGTTC TCCCAGAGGA ACAGGGGCCC 
AGCATCAAGA ACCTCGACTT CTGGTCCAAG CTGATTACCC TCATAGTGTC CATCATTGAG 
GAAGACAAGA ATTCCTACAC TCCCTGCCTC AACCAGTTTC CCCAGGAGCT GAATGTGGGT 
AAAATCAGCG CTGAAGTGAT GTGGAATCTG TTTGCCCAAG ACATGAAGTA CGCCATGGAG 
GAGCACGACA AGCATCGTCT ATGCAAGAGT GCCGACTACA TGAACCTCCA CTTCAAGGTG 
AAATGGCTCT ACAATGAGTA TGTGACGGAA CTTCCCGCCT TCAAGGACCG CGTGCCTGAG 
TACCCTGCAT GGTTTGAACC CTTCGTCATC CAGTGGCTGG ATGAGAATGA GGAGGTGTCC 
CGGGATTTCC TGCACGGTGC CCTGGAGCGA GACAAGAAGG ATGGGTTCCA GCAGACCTCA 
GAGCATGCCC TATTCTCCTG CTCCGTGGTG GATGTTTTCT CCCAACTCAA CCAGAGCTTT 
GAAATCATCA AGAAACTCGA GTGTCCCGAC CCTCAGATCG TGGGGCACTA CATGAGGCGC 
TTTGCCAAGA CCATCAGTAA TGTGCTCCTC CAGTATGCAG ACATCATCTC CAAGGACTTT 
GCCTCCTACT GCTCCAAGGA GAAGGAGAAA GTGCCCTGCA TTCTCATGAA TAACACTCAA 
CAGCTACGAG TTCAGCTGGA GAAGATGTTC GAAGCCATGG GAGGAAAGGA GCTGGATGCT 
GAAGCCAGTG ACATCCTGAA GGAGCTTCAG GTGAAACTCA ATAACGTCTT GGATGAGCTC 
AGCCGGGTGT TTGCTACCAG CTTCCAGCCG CACATTGAAG AGTGTGTCAA ACAGATGGGT 
GACATCCTTA GCCAGGTTAA GGGCACAGGC AATGTGCCAG CCAGTGCCTG CAGCAGCGTG 
GCCCAGGACG CGGACAATGT GTTGCAGCCC ATCATGGACC TGCTGGACAG CAACCTGACC 
CTCTTTGCCA AAATCTGTGA GAAGACTGTG CTGAAGCGAG TGCTGAAGGA GCTGTGGAAG 
CTGGTTATGA ACACCATGGA GAAAACCATC GTCCTGCCGC CCCTCACTGA CCAGACGATG 
ATCGGAACCC AGATGATCTT CAATGCAGCC AAGGAGCTGG GTCAGCTGTC CAAACTCAAG 
GATCACATGG TACGAGAAGA AGCCAAGAGC TTGACCCCAA AGCAGTGCGC GGTTGTTGAG 
TTGGCCCTGG ACACCATCAA GCAATATTTC CACGCGGGTG GCGTGGGCCT CAAGAAGACC 
TTCCTGGAGA AGAGCCCGGA CCTGCAATCC TTGCGCTATG CCCTGTCGCT CTACACGCAG 
GCCACCGACC TGCTAATCAA GACCTTTGTA CAGACGCAAT CGGCCCAGGG CTTGGGTGTA 
GAAGACCCTG TGGGTGAAGT CTCTGTCCAT GTTGAGCTGT TCACTCATCC AGGAACTGGG 
GAACACAAGG TCACAGTGAA AGTGGTGGCT GCCAATGACC TCAAGTGGCA GACTTCTGGC 
ATCTTCCGGC CGTTCATCGA GGTCAACATC ATTGGGCCCC AGCTCAGCGA CAAGAAACGC 
AAGTTTGCGA CCAAATCCAA GAACAATAGC TGGGCTCCCA AGTACAATGA GAGCTTCCAG 
TTCACGCTGA GCGCCGACGC GGGTCCCGAG TGCTATGAGC TGCAGGTGTG CGTCAAGGAC 
TACTGCTTCG CGCGCGAGGA CCGCACGGTG GGGCTGGCCG TGCTGCAGCT GCGTGAGCTG 
GCCCAGCGCG GGAGCGCCGC CTGCTGGCTG CCGCTCGGCC GCCGCATCCA CATGGACGAC 
ACGGGCCTCA CGGTGCTGCG AATCCTCTCG CAGCGCAGCA ACGACGAGGT GGCCAAGGAG 
TTCGTGAAGC TCAAGTCGGA CACGCGCTCC GCCGAGGAGG GCGGTGCCGC GCCTGCGCCT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UNC13A ( XM_017026502.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016881991.1 Homo sapiens unc-13 homolog A (UNC13A), transcript variant X1, mRNA.

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CloneID	OHu88318
Clone ID Related Accession (Same CDS sequence)	XM_017026502.1
Accession Version	XM_017026502.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5109bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein unc-13 homolog A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCTGC TTTGCGTTGG AGTCAAAAAA GCCAAGTTTG ATGGTGCCCA AGAGAAATTC 
AACACGTACG TGACCCTGAA AGTGCAGAAT GTCAAGAGCA CGACCATCGC GGTGCGGGGC 
AGCCAGCCCA GCTGGGAGCA GGATTTCATG TTCGAGATTA ACCGTCTGGA TTTGGGACTG 
ACGGTGGAGG TGTGGAATAA GGGTCTCATC TGGGACACAA TGGTGGGCAC TGTGTGGATC 
CCACTGAGGA CCATCCGCCA GTCCAATGAG GAGGGCCCTG GAGAGTGGCT GACGCTGGAC 
TCCCAGGTCA TCATGGCAGA CAGTGAGATC TGTGGCACCA AGGACCCCAC CTTCCACCGC 
ATCCTCCTGG ACACGCGCTT TGAGCTACCC TTAGACATTC CTGAAGAGGA GGCTCGCTAC 
TGGGCCAAGA AGCTGGAGCA GCTCAATGCT ATGCGGGACC AGGATGAATA TTCGTTCCAA 
GATGAGCAAG ACAAGCCTCT GCCTGTCCCC AGCAACCAGT GCTGCAACTG GAATTATTTT 
GGCTGGGGTG AGCAGCACAA CGATGACCCC GACAGTGCAG TGGATGATCG TGACAGTGAC 
TACCGCAGTG AAACGAGCAA CAGCATCCCG CCGCCCTATT ATACTACGTC ACAACCCAAC 
GCCTCAGTCC ACCAATATTC TGTTCGCCCA CCACCCCTGG GCTCCCGGGA GTCCTACAGT 
GACTCCATGC ACAGTTACGA GGAGTTCTCT GAGCCACAAG CCCTCAGCCC CACGGGTAGC 
AGCCGCTATG CCTCTTCCGG GGAGCTGAGC CAGGGAAGCT CTCAGCTGAG CGAGGACTTC 
GACCCTGACG AGCACAGCCT GCAGGGCTCC GACATGGAGG ATGAGCGGGA CCGGGACTCC 
TACCACTCCT GCCACAGCTC GGTCAGCTAC CACAAAGACT CGCCTCGCTG GGACCAGGAT 
GAGGAAGAGC TGGAGGAGGA CCTGGAGGAC TTCCTGGAGG AGGAGGAGCT GCCTGAAGAT 
GAGGAGGAGC TGGAGGAGGA GGAGGAGGAG GTGCCTGACG ATTTGGGCAG CTATGCCCAG 
CGTGAAGACG TAGCTGTGGC TGAGCCCAAA GACTTCAAAC GCATCAGCCT CCCGCCAGCT 
GCCCCAGGGA AGGAGGACAA GGCCCCAGTG GCACCCACCG AGGCCCCCGA CATGGCCAAG 
GTGGCCCCCA AGCCAGCCAC GCCCGACAAG GTGCCTGCAG CTGAGCAGAT CCCTGAGGCT 
GAGCCACCCA AGGACGAGGA GAGTTTCAGG CCGAGAGAGG ATGAGGAAGG CCAGGAGGGG 
CAGGACTCCA TGTCCAGGGC CAAGGCCAAC TGGCTGCGTG CCTTCAACAA GGTGCGGATG 
CAGCTGCAGG AGGCCCGGGG AGAAGGAGAG ATGTCTAAAT CCCTATGGTT CAAAGGCGGC 
CCAGGGGGCG GTCTCATCAT CATCGACAGC ATGCCAGACA TCCGCAAGAG GAAACCTATC 
CCACTCGTGA GCGACTTGGC CATGTCCCTG GTCCAGTCCA GGAAAGCGGG CATCACCTCG 
GCCTTGGCCT CCAGCACGTT GAACAACGAG GAGCTGAAAA ACCACGTTTA CAAGAAGACC 
CTGCAAGCCT TAATCTACCC CATCTCGTGC ACGACGCCAC ACAACTTCGA AGTGTGGACG 
GCCACCACGC CCACCTACTG CTACGAGTGC GAGGGGCTGC TGTGGGGCAT CGCGAGGCAG 
GGCATGCGCT GCACCGAGTG CGGTGTCAAG TGCCACGAGA AGTGCCAGGA CCTGCTCAAC 
GCCGACTGCC TGCAGCGGGC TGCGGAGAAG AGCTCCAAGC ACGGGGCGGA GGACCGGACA 
CAGAACATCA TCATGGTGCT CAAGGACCGC ATGAAGATCC GGGAGCGCAA CAAGCCCGAG 
ATCTTCGAGC TCATCCAGGA GATCTTCGCG GTGACCAAGA CGGCGCACAC GCAGCAGATG 
AAGGCGGTCA AGCAGAGCGT GCTGGACGGC ACGTCCAAGT GGTCCGCCAA GATCAGCATC 
ACCGTGGTCT GCGCCCAGGG CTTGCAGGCA AAGGACAAGA CAGGATCCAG TGACCCCTAT 
GTCACCGTCC AGGTCGGGAA GACCAAGAAA CGGACAAAAA CCATCTATGG GAACCTCAAC 
CCGGTGTGGG AGGAGAATTT CCACTTTGAA TGTCACAATT CCTCCGACCG CATCAAGGTG 
CGCGTCTGGG ACGAGGATGA CGACATCAAA TCCCGCGTGA AACAGAGGTT CAAGAGGGAA 
TCTGACGATT TCCTGGGGCA GACGATCATT GAGGTGCGGA CGCTCAGCGG CGAGATGGAC 
GTGTGGTACA ACCTGGACAA GCGAACTGAC AAATCTGCCG TGTCGGGTGC CATCCGGCTC 
CACATCAGTG TGGAGATCAA AGGCGAGGAG AAGGTGGCCC CGTACCATGT CCAGTACACC 
TGTCTGCATG AGAACCTGTT CCACTTCGTG ACCGACGTGC AGAACAATGG GGTCGTGAAG 
ATCCCAGATG CCAAGGGTGA CGATGCCTGG AAGGTTTACT ACGATGAGAC AGCCCAGGAG 
ATTGTGGACG AGTTTGCCAT GCGCTACGGC GTCGAGTCCA TCTACCAAGC CATGACCCAC 
TTTGCCTGCC TCTCCTCCAA GTATATGTGC CCAGGGGTGC CTGCCGTCAT GAGCACCCTG 
CTCGCCAACA TCAATGCCTA CTACGCACAC ACCACCGCCT CCACCAACGT GTCTGCCTCC 
GACCGCTTCG CCGCCTCCAA CTTTGGGAAA GAGCGCTTCG TGAAACTCCT GGACCAGCTG 
CATAACTCCC TGCGGATTGA CCTCTCCATG TACCGGAATA ACTTCCCAGC CAGCAGCCCG 
GAGAGACTCC AGGACCTCAA ATCCACTGTG GACCTTCTCA CCAGCATCAC CTTCTTTCGG 
ATGAAGGTAC AAGAACTCCA GAGCCCGCCC CGAGCCAGCC AGGTGGTAAA GGACTGTGTG 
AAAGCCTGCC TTAATTCTAC CTACGAGTAC ATCTTCAATA ACTGCCATGA ACTGTACAGC 
CGGGAGTACC AGACAGACCC GGCCAAGAAG GGGGAAGTTC TCCCAGAGGA ACAGGGGCCC 
AGCATCAAGA ACCTCGACTT CTGGTCCAAG CTGATTACCC TCATAGTGTC CATCATTGAG 
GAAGACAAGA ATTCCTACAC TCCCTGCCTC AACCAGTTTC CCCAGGAGCT GAATGTGGGT 
AAAATCAGCG CTGAAGTGAT GTGGAATCTG TTTGCCCAAG ACATGAAGTA CGCCATGGAG 
GAGCACGACA AGCATCGTCT ATGCAAGAGT GCCGACTACA TGAACCTCCA CTTCAAGGTG 
AAATGGCTCT ACAATGAGTA TGTGACGGAA CTTCCCGCCT TCAAGGACCG CGTGCCTGAG 
TACCCTGCAT GGTTTGAACC CTTCGTCATC CAGTGGCTGG ATGAGAATGA GGAGGTGTCC 
CGGGATTTCC TGCACGGTGC CCTGGAGCGA GACAAGAAGG ATGGGTTCCA GCAGACCTCA 
GAGCATGCCC TATTCTCCTG CTCCGTGGTG GATGTTTTCT CCCAACTCAA CCAGAGCTTT 
GAAATCATCA AGAAACTCGA GTGTCCCGAC CCTCAGATCG TGGGGCACTA CATGAGGCGC 
TTTGCCAAGA CCATCAGTAA TGTGCTCCTC CAGTATGCAG ACATCATCTC CAAGGACTTT 
GCCTCCTACT GCTCCAAGGA GAAGGAGAAA CCCTGCATTC TCATGAATAA CACTCAACAG 
CTACGAGTTC AGCTGGAGAA GATGTTCGAA GCCATGGGAG GAAAGGAGCT GGATGCTGAA 
GCCAGTGACA TCCTGAAGGA GCTTCAGGTG AAACTCAATA ACGTCTTGGA TGAGCTCAGC 
CGGGTGTTTG CTACCAGCTT CCAGCCGCAC ATTGAAGAGT GTGTCAAACA GATGGGTGAC 
ATCCTTAGCC AGGTTAAGGG CACAGGCAAT GTGCCAGCCA GTGCCTGCAG CAGCGTGGCC 
CAGGACGCGG ACAATGTGTT GCAGCCCATC ATGGACCTGC TGGACAGCAA CCTGACCCTC 
TTTGCCAAAA TCTGTGAGAA GACTGTGCTG AAGCGAGTGC TGAAGGAGCT GTGGAAGCTG 
GTTATGAACA CCATGGAGAA AACCATCGTC CTGCCGCCCC TCACTGACCA GACGATGATC 
GGGAACCTCT TGAGAAAACA TGGCAAGGGA TTAGAAAAGG GCAGGGTGAA ATTGCCAAGC 
CACTCAGACG GAACCCAGAT GATCTTCAAT GCAGCCAAGG AGCTGGGTCA GCTGTCCAAA 
CTCAAGGATC ACATGGTACG AGAAGAAGCC AAGAGCTTGA CCCCAAAGCA GTGCGCGGTT 
GTTGAGTTGG CCCTGGACAC CATCAAGCAA TATTTCCACG CGGGTGGCGT GGGCCTCAAG 
AAGACCTTCC TGGAGAAGAG CCCGGACCTG CAATCCTTGC GCTATGCCCT GTCGCTCTAC 
ACGCAGGCCA CCGACCTGCT AATCAAGACC TTTGTACAGA CGCAATCGGC CCAGGGCTTG 
GGTGTAGAAG ACCCTGTGGG TGAAGTCTCT GTCCATGTTG AGCTGTTCAC TCATCCAGGA 
ACTGGGGAAC ACAAGGTCAC AGTGAAAGTG GTGGCTGCCA ATGACCTCAA GTGGCAGACT 
TCTGGCATCT TCCGGCCGTT CATCGAGGTC AACATCATTG GGCCCCAGCT CAGCGACAAG 
AAACGCAAGT TTGCGACCAA ATCCAAGAAC AATAGCTGGG CTCCCAAGTA CAATGAGAGC 
TTCCAGTTCA CGCTGAGCGC CGACGCGGGT CCCGAGTGCT ATGAGCTGCA GGTGTGCGTC 
AAGGACTACT GCTTCGCGCG CGAGGACCGC ACGGTGGGGC TGGCCGTGCT GCAGCTGCGT 
GAGCTGGCCC AGCGCGGGAG CGCCGCCTGC TGGCTGCCGC TCGGCCGCCG CATCCACATG 
GACGACACGG GCCTCACGGT GCTGCGAATC CTCTCGCAGC GCAGCAACGA CGAGGTGGCC 
AAGGAGTTCG TGAAGCTCAA GTCGGACACG CGCTCCGCCG AGGAGGGCGG TGCCGCGCCT 
GCGCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016881991.1
CDS	146..5254
Translation	MSLLCVGVKKAKFDGAQEKFNTYVTLKVQNVKSTTIAVRGSQPSWEQDFMFEINRLDLGLTVEVWNKGLIWDTMVGTVWIPLRTIRQSNEEGPGEWLTLDSQVIMADSEICGTKDPTFHRILLDTRFELPLDIPEEEARYWAKKLEQLNAMRDQDEYSFQDEQDKPLPVPSNQCCNWNYFGWGEQHNDDPDSAVDDRDSDYRSETSNSIPPPYYTTSQPNASVHQYSVRPPPLGSRESYSDSMHSYEEFSEPQALSPTGSSRYASSGELSQGSSQLSEDFDPDEHSLQGSDMEDERDRDSYHSCHSSVSYHKDSPRWDQDEEELEEDLEDFLEEEELPEDEEELEEEEEEVPDDLGSYAQREDVAVAEPKDFKRISLPPAAPGKEDKAPVAPTEAPDMAKVAPKPATPDKVPAAEQIPEAEPPKDEESFRPREDEEGQEGQDSMSRAKANWLRAFNKVRMQLQEARGEGEMSKSLWFKGGPGGGLIIIDSMPDIRKRKPIPLVSDLAMSLVQSRKAGITSALASSTLNNEELKNHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDRTQNIIMVLKDRMKIRERNKPEIFELIQEIFAVTKTAHTQQMKAVKQSVLDGTSKWSAKISITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHFECHNSSDRIKVRVWDEDDDIKSRVKQRFKRESDDFLGQTIIEVRTLSGEMDVWYNLDKRTDKSAVSGAIRLHISVEIKGEEKVAPYHVQYTCLHENLFHFVTDVQNNGVVKIPDAKGDDAWKVYYDETAQEIVDEFAMRYGVESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHELYSREYQTDPAKKGEVLPEEQGPSIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVGKISAEVMWNLFAQDMKYAMEEHDKHRLCKSADYMNLHFKVKWLYNEYVTELPAFKDRVPEYPAWFEPFVIQWLDENEEVSRDFLHGALERDKKDGFQQTSEHALFSCSVVDVFSQLNQSFEIIKKLECPDPQIVGHYMRRFAKTISNVLLQYADIISKDFASYCSKEKEKPCILMNNTQQLRVQLEKMFEAMGGKELDAEASDILKELQVKLNNVLDELSRVFATSFQPHIEECVKQMGDILSQVKGTGNVPASACSSVAQDADNVLQPIMDLLDSNLTLFAKICEKTVLKRVLKELWKLVMNTMEKTIVLPPLTDQTMIGNLLRKHGKGLEKGRVKLPSHSDGTQMIFNAAKELGQLSKLKDHMVREEAKSLTPKQCAVVELALDTIKQYFHAGGVGLKKTFLEKSPDLQSLRYALSLYTQATDLLIKTFVQTQSAQGLGVEDPVGEVSVHVELFTHPGTGEHKVTVKVVAANDLKWQTSGIFRPFIEVNIIGPQLSDKKRKFATKSKNNSWAPKYNESFQFTLSADAGPECYELQVCVKDYCFAREDRTVGLAVLQLRELAQRGSAACWLPLGRRIHMDDTGLTVLRILSQRSNDEVAKEFVKLKSDTRSAEEGGAAPAP

Target ORF information:

RefSeq Version	XM_017026502.1
Organism	Homo sapiens(human)
Definition	Homo sapiens unc-13 homolog A (UNC13A), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026502.1

ORF Insert Sequence:

ATGTCTCTGC TTTGCGTTGG AGTCAAAAAA GCCAAGTTTG ATGGTGCCCA AGAGAAATTC 
AACACGTACG TGACCCTGAA AGTGCAGAAT GTCAAGAGCA CGACCATCGC GGTGCGGGGC 
AGCCAGCCCA GCTGGGAGCA GGATTTCATG TTCGAGATTA ACCGTCTGGA TTTGGGACTG 
ACGGTGGAGG TGTGGAATAA GGGTCTCATC TGGGACACAA TGGTGGGCAC TGTGTGGATC 
CCACTGAGGA CCATCCGCCA GTCCAATGAG GAGGGCCCTG GAGAGTGGCT GACGCTGGAC 
TCCCAGGTCA TCATGGCAGA CAGTGAGATC TGTGGCACCA AGGACCCCAC CTTCCACCGC 
ATCCTCCTGG ACACGCGCTT TGAGCTACCC TTAGACATTC CTGAAGAGGA GGCTCGCTAC 
TGGGCCAAGA AGCTGGAGCA GCTCAATGCT ATGCGGGACC AGGATGAATA TTCGTTCCAA 
GATGAGCAAG ACAAGCCTCT GCCTGTCCCC AGCAACCAGT GCTGCAACTG GAATTATTTT 
GGCTGGGGTG AGCAGCACAA CGATGACCCC GACAGTGCAG TGGATGATCG TGACAGTGAC 
TACCGCAGTG AAACGAGCAA CAGCATCCCG CCGCCCTATT ATACTACGTC ACAACCCAAC 
GCCTCAGTCC ACCAATATTC TGTTCGCCCA CCACCCCTGG GCTCCCGGGA GTCCTACAGT 
GACTCCATGC ACAGTTACGA GGAGTTCTCT GAGCCACAAG CCCTCAGCCC CACGGGTAGC 
AGCCGCTATG CCTCTTCCGG GGAGCTGAGC CAGGGAAGCT CTCAGCTGAG CGAGGACTTC 
GACCCTGACG AGCACAGCCT GCAGGGCTCC GACATGGAGG ATGAGCGGGA CCGGGACTCC 
TACCACTCCT GCCACAGCTC GGTCAGCTAC CACAAAGACT CGCCTCGCTG GGACCAGGAT 
GAGGAAGAGC TGGAGGAGGA CCTGGAGGAC TTCCTGGAGG AGGAGGAGCT GCCTGAAGAT 
GAGGAGGAGC TGGAGGAGGA GGAGGAGGAG GTGCCTGACG ATTTGGGCAG CTATGCCCAG 
CGTGAAGACG TAGCTGTGGC TGAGCCCAAA GACTTCAAAC GCATCAGCCT CCCGCCAGCT 
GCCCCAGGGA AGGAGGACAA GGCCCCAGTG GCACCCACCG AGGCCCCCGA CATGGCCAAG 
GTGGCCCCCA AGCCAGCCAC GCCCGACAAG GTGCCTGCAG CTGAGCAGAT CCCTGAGGCT 
GAGCCACCCA AGGACGAGGA GAGTTTCAGG CCGAGAGAGG ATGAGGAAGG CCAGGAGGGG 
CAGGACTCCA TGTCCAGGGC CAAGGCCAAC TGGCTGCGTG CCTTCAACAA GGTGCGGATG 
CAGCTGCAGG AGGCCCGGGG AGAAGGAGAG ATGTCTAAAT CCCTATGGTT CAAAGGCGGC 
CCAGGGGGCG GTCTCATCAT CATCGACAGC ATGCCAGACA TCCGCAAGAG GAAACCTATC 
CCACTCGTGA GCGACTTGGC CATGTCCCTG GTCCAGTCCA GGAAAGCGGG CATCACCTCG 
GCCTTGGCCT CCAGCACGTT GAACAACGAG GAGCTGAAAA ACCACGTTTA CAAGAAGACC 
CTGCAAGCCT TAATCTACCC CATCTCGTGC ACGACGCCAC ACAACTTCGA AGTGTGGACG 
GCCACCACGC CCACCTACTG CTACGAGTGC GAGGGGCTGC TGTGGGGCAT CGCGAGGCAG 
GGCATGCGCT GCACCGAGTG CGGTGTCAAG TGCCACGAGA AGTGCCAGGA CCTGCTCAAC 
GCCGACTGCC TGCAGCGGGC TGCGGAGAAG AGCTCCAAGC ACGGGGCGGA GGACCGGACA 
CAGAACATCA TCATGGTGCT CAAGGACCGC ATGAAGATCC GGGAGCGCAA CAAGCCCGAG 
ATCTTCGAGC TCATCCAGGA GATCTTCGCG GTGACCAAGA CGGCGCACAC GCAGCAGATG 
AAGGCGGTCA AGCAGAGCGT GCTGGACGGC ACGTCCAAGT GGTCCGCCAA GATCAGCATC 
ACCGTGGTCT GCGCCCAGGG CTTGCAGGCA AAGGACAAGA CAGGATCCAG TGACCCCTAT 
GTCACCGTCC AGGTCGGGAA GACCAAGAAA CGGACAAAAA CCATCTATGG GAACCTCAAC 
CCGGTGTGGG AGGAGAATTT CCACTTTGAA TGTCACAATT CCTCCGACCG CATCAAGGTG 
CGCGTCTGGG ACGAGGATGA CGACATCAAA TCCCGCGTGA AACAGAGGTT CAAGAGGGAA 
TCTGACGATT TCCTGGGGCA GACGATCATT GAGGTGCGGA CGCTCAGCGG CGAGATGGAC 
GTGTGGTACA ACCTGGACAA GCGAACTGAC AAATCTGCCG TGTCGGGTGC CATCCGGCTC 
CACATCAGTG TGGAGATCAA AGGCGAGGAG AAGGTGGCCC CGTACCATGT CCAGTACACC 
TGTCTGCATG AGAACCTGTT CCACTTCGTG ACCGACGTGC AGAACAATGG GGTCGTGAAG 
ATCCCAGATG CCAAGGGTGA CGATGCCTGG AAGGTTTACT ACGATGAGAC AGCCCAGGAG 
ATTGTGGACG AGTTTGCCAT GCGCTACGGC GTCGAGTCCA TCTACCAAGC CATGACCCAC 
TTTGCCTGCC TCTCCTCCAA GTATATGTGC CCAGGGGTGC CTGCCGTCAT GAGCACCCTG 
CTCGCCAACA TCAATGCCTA CTACGCACAC ACCACCGCCT CCACCAACGT GTCTGCCTCC 
GACCGCTTCG CCGCCTCCAA CTTTGGGAAA GAGCGCTTCG TGAAACTCCT GGACCAGCTG 
CATAACTCCC TGCGGATTGA CCTCTCCATG TACCGGAATA ACTTCCCAGC CAGCAGCCCG 
GAGAGACTCC AGGACCTCAA ATCCACTGTG GACCTTCTCA CCAGCATCAC CTTCTTTCGG 
ATGAAGGTAC AAGAACTCCA GAGCCCGCCC CGAGCCAGCC AGGTGGTAAA GGACTGTGTG 
AAAGCCTGCC TTAATTCTAC CTACGAGTAC ATCTTCAATA ACTGCCATGA ACTGTACAGC 
CGGGAGTACC AGACAGACCC GGCCAAGAAG GGGGAAGTTC TCCCAGAGGA ACAGGGGCCC 
AGCATCAAGA ACCTCGACTT CTGGTCCAAG CTGATTACCC TCATAGTGTC CATCATTGAG 
GAAGACAAGA ATTCCTACAC TCCCTGCCTC AACCAGTTTC CCCAGGAGCT GAATGTGGGT 
AAAATCAGCG CTGAAGTGAT GTGGAATCTG TTTGCCCAAG ACATGAAGTA CGCCATGGAG 
GAGCACGACA AGCATCGTCT ATGCAAGAGT GCCGACTACA TGAACCTCCA CTTCAAGGTG 
AAATGGCTCT ACAATGAGTA TGTGACGGAA CTTCCCGCCT TCAAGGACCG CGTGCCTGAG 
TACCCTGCAT GGTTTGAACC CTTCGTCATC CAGTGGCTGG ATGAGAATGA GGAGGTGTCC 
CGGGATTTCC TGCACGGTGC CCTGGAGCGA GACAAGAAGG ATGGGTTCCA GCAGACCTCA 
GAGCATGCCC TATTCTCCTG CTCCGTGGTG GATGTTTTCT CCCAACTCAA CCAGAGCTTT 
GAAATCATCA AGAAACTCGA GTGTCCCGAC CCTCAGATCG TGGGGCACTA CATGAGGCGC 
TTTGCCAAGA CCATCAGTAA TGTGCTCCTC CAGTATGCAG ACATCATCTC CAAGGACTTT 
GCCTCCTACT GCTCCAAGGA GAAGGAGAAA CCCTGCATTC TCATGAATAA CACTCAACAG 
CTACGAGTTC AGCTGGAGAA GATGTTCGAA GCCATGGGAG GAAAGGAGCT GGATGCTGAA 
GCCAGTGACA TCCTGAAGGA GCTTCAGGTG AAACTCAATA ACGTCTTGGA TGAGCTCAGC 
CGGGTGTTTG CTACCAGCTT CCAGCCGCAC ATTGAAGAGT GTGTCAAACA GATGGGTGAC 
ATCCTTAGCC AGGTTAAGGG CACAGGCAAT GTGCCAGCCA GTGCCTGCAG CAGCGTGGCC 
CAGGACGCGG ACAATGTGTT GCAGCCCATC ATGGACCTGC TGGACAGCAA CCTGACCCTC 
TTTGCCAAAA TCTGTGAGAA GACTGTGCTG AAGCGAGTGC TGAAGGAGCT GTGGAAGCTG 
GTTATGAACA CCATGGAGAA AACCATCGTC CTGCCGCCCC TCACTGACCA GACGATGATC 
GGGAACCTCT TGAGAAAACA TGGCAAGGGA TTAGAAAAGG GCAGGGTGAA ATTGCCAAGC 
CACTCAGACG GAACCCAGAT GATCTTCAAT GCAGCCAAGG AGCTGGGTCA GCTGTCCAAA 
CTCAAGGATC ACATGGTACG AGAAGAAGCC AAGAGCTTGA CCCCAAAGCA GTGCGCGGTT 
GTTGAGTTGG CCCTGGACAC CATCAAGCAA TATTTCCACG CGGGTGGCGT GGGCCTCAAG 
AAGACCTTCC TGGAGAAGAG CCCGGACCTG CAATCCTTGC GCTATGCCCT GTCGCTCTAC 
ACGCAGGCCA CCGACCTGCT AATCAAGACC TTTGTACAGA CGCAATCGGC CCAGGGCTTG 
GGTGTAGAAG ACCCTGTGGG TGAAGTCTCT GTCCATGTTG AGCTGTTCAC TCATCCAGGA 
ACTGGGGAAC ACAAGGTCAC AGTGAAAGTG GTGGCTGCCA ATGACCTCAA GTGGCAGACT 
TCTGGCATCT TCCGGCCGTT CATCGAGGTC AACATCATTG GGCCCCAGCT CAGCGACAAG 
AAACGCAAGT TTGCGACCAA ATCCAAGAAC AATAGCTGGG CTCCCAAGTA CAATGAGAGC 
TTCCAGTTCA CGCTGAGCGC CGACGCGGGT CCCGAGTGCT ATGAGCTGCA GGTGTGCGTC 
AAGGACTACT GCTTCGCGCG CGAGGACCGC ACGGTGGGGC TGGCCGTGCT GCAGCTGCGT 
GAGCTGGCCC AGCGCGGGAG CGCCGCCTGC TGGCTGCCGC TCGGCCGCCG CATCCACATG 
GACGACACGG GCCTCACGGT GCTGCGAATC CTCTCGCAGC GCAGCAACGA CGAGGTGGCC 
AAGGAGTTCG TGAAGCTCAA GTCGGACACG CGCTCCGCCG AGGAGGGCGG TGCCGCGCCT 
GCGCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Rare genetic variation in UNC13A may modify survival in amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis & frontotemporal degeneration17(7-8)593-599(2016 Oct - Nov)
Gaastra B,Shatunov A,Pulit S,Jones AR,Sproviero W,Gillett A,Chen Z,Kirby J,Fogh I,Powell JF,Leigh PN,Morrison KE,Shaw PJ,Shaw CE,van den Berg LH,Veldink JH,Lewis CM,Al-Chalabi A

Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder.
The Journal of clinical investigation127(3)1005-1018(2017 Mar)
Lipstein N,Verhoeven-Duif NM,Michelassi FE,Calloway N,van Hasselt PM,Pienkowska K,van Haaften G,van Haelst MM,van Empelen R,Cuppen I,van Teeseling HC,Evelein AM,Vorstman JA,Thoms S,Jahn O,Duran KJ,Monroe GR,Ryan TA,Taschenberger H,Dittman JS,Rhee JS,Visser G,Jans JJ,Brose N

UNC13A confers risk for sporadic ALS and influences survival in a Spanish cohort.
Journal of neurology262(10)2285-92(2015 Oct)
Vidal-Taboada JM,Lopez-Lopez A,Salvado M,Lorenzo L,Garcia C,Mahy N,Rodr?guez MJ,Gamez J

C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis.
Annals of neurology76(1)120-33(2014 Jul)
Diekstra FP,Van Deerlin VM,van Swieten JC,Al-Chalabi A,Ludolph AC,Weishaupt JH,Hardiman O,Landers JE,Brown RH Jr,van Es MA,Pasterkamp RJ,Koppers M,Andersen PM,Estrada K,Rivadeneira F,Hofman A,Uitterlinden AG,van Damme P,Melki J,Meininger V,Shatunov A,Shaw CE,Leigh PN,Shaw PJ,Morrison KE,Fogh I,Chi? A,Traynor BJ,Czell D,Weber M,Heutink P,de Bakker PI,Silani V,Robberecht W,van den Berg LH,Veldink JH

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UNC13A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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