Gene Symbol | SLC30A8 |
Entrez Gene ID | 169026 |
Full Name | solute carrier family 30 member 8 |
Synonyms | ZNT8,ZnT-8 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]. |
Disorder MIM: | |
Disorder Html: | {Diabetes mellitus, noninsulin-dependent, susceptibility to}, 125853 (3) |