REM2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	REM2
Entrez Gene ID	161253
Full Name	RRAD and GEM like GTPase 2
General protein information	Preferred Names RRAD and GEM like GTPase 2 Names GTP-binding protein REM 2 RAS (RAD and GEM)-like GTP binding 2 RAS-like GTP binding 2 Rad and Gem-related 2 (rat homolog) rad and Gem-like GTP-binding protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q11.2
Disorder MIM:	616955

mRNA and Protein(s)

mRNA	Protein	Name
NM_173527.2	NP_775798.2	GTP-binding protein REM 2
NM_173527.3	NP_775798.2	GTP-binding protein REM 2
XM_017021059.1	XP_016876548.1	GTP-binding protein REM 2 isoform X2
XM_011536518.2	XP_011534820.1	GTP-binding protein REM 2 isoform X4
XM_005267383.3	XP_005267440.1	GTP-binding protein REM 2 isoform X3
XM_017021058.1	XP_016876547.1	GTP-binding protein REM 2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	REM2	NP_775798.2
Canis lupus familiaris (dog)	REM2	XP_005623273.1
Bos taurus (cattle)	REM2	NP_001179637.1
Xenopus tropicalis (tropical clawed frog)	rem2	XP_002941555.1
Pan troglodytes (chimpanzee)	REM2	XP_522796.2
	LOC712572	XP_001100692.1
Mus musculus (house mouse)	Rem2	NP_542764.2
Rattus norvegicus (Norway rat)	Rem2	NP_073176.2

Gene Ontology
Bibliography

Related articles in PubMed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

A loss-of-function analysis reveals that endogenous Rem2 promotes functional glutamatergic synapse formation and restricts dendritic complexity.
Moore AR, Ghiretti AE, Paradis S
PloS one8(8)e74751(2013)

Activity-dependent subcellular cotrafficking of the small GTPase Rem2 and Ca2+/CaM-dependent protein kinase II?.
Flynn R, Labrie-Dion E, Bernier N, Colicos MA, De Koninck P, Zamponi GW
PloS one7(7)e41185(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

conclude that endogenous Rem2 is a positive regulator of functional, excitatory synapse development and a negative regulator of dendritic complexity
Title: A loss-of-function analysis reveals that endogenous Rem2 promotes functional glutamatergic synapse formation and restricts dendritic complexity.

Rem2 has a role in neuronal plasticity hrough co-trafficking with CaMKIIa
Title: Activity-dependent subcellular cotrafficking of the small GTPase Rem2 and Ca2+/CaM-dependent protein kinase II?.

our results suggest that Rem2 regulates dendritic branching and synapse development
Title: The GTPase Rem2 regulates synapse development and dendritic morphology.

molecular mechanisms by which Rem2 knockdown affected synaptogenesis and Ca(2) homeostasis in cultured rat hippocampal neurons
Title: Rem2-targeted shRNAs reduce frequency of miniature excitatory postsynaptic currents without altering voltage-gated Ca?? currents.

Rem2 mediates the fibroblastic growth factor 2 (FGF2) signaling pathway to maintain proliferation of hESCsby suppressing the transcriptional activity of p53 and cyclin D(1)
Title: Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1.

The following REM2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the REM2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07281	NM_173527.3 Latest version!	Homo sapiens RRAD and GEM like GTPase 2 (REM2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu47565	XM_005267383.3 Latest version!	Homo sapiens RRAD and GEM like GTPase 2 (REM2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu77110	XM_011536518.2 Latest version!	Homo sapiens RRAD and GEM like GTPase 2 (REM2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu84806	XM_017021058.1 Latest version!	Homo sapiens RRAD and GEM like GTPase 2 (REM2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu84807	XM_017021059.1 Latest version!	Homo sapiens RRAD and GEM like GTPase 2 (REM2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu07281	NM_173527.2	Homo sapiens RRAD and GEM like GTPase 2 (REM2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

REM2 ( NM_173527.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_775798.2 Homo sapiens RRAD and GEM like GTPase 2 (REM2), mRNA.

Price & Availability↑

CloneID	OHu07281
Clone ID Related Accession (Same CDS sequence)	NM_173527.2 , NM_173527.3
Accession Version	NM_173527.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1023bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	GTP-binding protein REM 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK096283.1 and BC035663.1. On Jan 27, 2007 this sequence version replaced NM_173527.1. ##Evidence-Data-START## Transcript exon combination :: BC035663.1, KU178879.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END##

ATGCACACGG ACCTGGACAC AGACATGGAC ATGGACACAG AAACCACAGC ACTCTGCCCC 
TCTGGCAGCC GCCGGGCCTC CCCTCCAGGG ACGCCCACAC CAGAAGCAGA TGCCACGCTA 
CTAAAGAAGT CAGAGAAACT GTTGGCAGAG TTGGACCGGA GCGGGTTACC CTCTGCCCCT 
GGGGCCCCCA GACGAAGAGG CAGTATGCCT GTCCCCTACA AGCACCAGCT CCGGCGGGCC 
CAGGCTGTAG ATGAACTTGA CTGGCCACCT CAGGCCTCAT CCTCTGGCTC GTCTGACTCC 
TTGGGCTCAG GGGAGGCAGC CCCTGCTCAA AAGGATGGCA TCTTCAAGGT CATGCTAGTG 
GGGGAGAGCG GCGTGGGCAA GAGCACCCTA GCAGGCACTT TTGGTGGTCT CCAGGGAGAC 
AGTGCTCACG AACCGGAGAA CCCAGAGGAT ACCTATGAGA GACGCATCAT GGTGGATAAG 
GAGGAAGTGA CTCTAGTCGT TTATGACATC TGGGAACAGG GGGATGCAGG AGGGTGGCTG 
CGGGACCACT GCCTTCAGAC CGGGGACGCC TTTCTCATCG TCTTCTCAGT CACCGACCGA 
CGGAGTTTCT CCAAAGTTCC AGAGACCCTA CTTCGGCTCC GGGCTGGGAG GCCGCACCAC 
GACCTACCCG TTATCCTCGT TGGAAACAAG AGCGACTTGG CCCGCTCCCG GGAGGTATCA 
CTGGAGGAGG GCCGCCACCT GGCCGGGACG CTGAGCTGCA AGCACATCGA GACGTCGGCC 
GCACTGCACC ACAACACGAG GGAGCTCTTC GAGGGCGCGG TGCGCCAGAT CCGGCTGCGG 
CGGGGCCGAA ACCACGCCGG AGGCCAGAGG CCCGATCCGG GCAGCCCCGA GGGCCCTGCG 
CCACCTGCAC GCCGCGAGAG CCTCACCAAG AAAGCCAAGA GGTTCCTCGC CAACCTGGTG 
CCGCGCAACG CCAAGTTCTT CAAGCAGCGC TCCAGGTCGT GTCACGACCT CTCGGTGCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775798.2
CDS	66..1088
Translation	MHTDLDTDMDMDTETTALCPSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVGKSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL

Target ORF information:

RefSeq Version	NM_173527.2
Organism	Homo sapiens(human)
Definition	Homo sapiens RRAD and GEM like GTPase 2 (REM2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173527.2

ORF Insert Sequence:

ATGCACACGG ACCTGGACAC AGACATGGAC ATGGACACAG AAACCACAGC ACTCTGCCCC 
TCTGGCAGCC GCCGGGCCTC CCCTCCAGGG ACGCCCACAC CAGAAGCAGA TGCCACGCTA 
CTAAAGAAGT CAGAGAAACT GTTGGCAGAG TTGGACCGGA GCGGGTTACC CTCTGCCCCT 
GGGGCCCCCA GACGAAGAGG CAGTATGCCT GTCCCCTACA AGCACCAGCT CCGGCGGGCC 
CAGGCTGTAG ATGAACTTGA CTGGCCACCT CAGGCCTCAT CCTCTGGCTC GTCTGACTCC 
TTGGGCTCAG GGGAGGCAGC CCCTGCTCAA AAGGATGGCA TCTTCAAGGT CATGCTAGTG 
GGGGAGAGCG GCGTGGGCAA GAGCACCCTA GCAGGCACTT TTGGTGGTCT CCAGGGAGAC 
AGTGCTCACG AACCGGAGAA CCCAGAGGAT ACCTATGAGA GACGCATCAT GGTGGATAAG 
GAGGAAGTGA CTCTAGTCGT TTATGACATC TGGGAACAGG GGGATGCAGG AGGGTGGCTG 
CGGGACCACT GCCTTCAGAC CGGGGACGCC TTTCTCATCG TCTTCTCAGT CACCGACCGA 
CGGAGTTTCT CCAAAGTTCC AGAGACCCTA CTTCGGCTCC GGGCTGGGAG GCCGCACCAC 
GACCTACCCG TTATCCTCGT TGGAAACAAG AGCGACTTGG CCCGCTCCCG GGAGGTATCA 
CTGGAGGAGG GCCGCCACCT GGCCGGGACG CTGAGCTGCA AGCACATCGA GACGTCGGCC 
GCACTGCACC ACAACACGAG GGAGCTCTTC GAGGGCGCGG TGCGCCAGAT CCGGCTGCGG 
CGGGGCCGAA ACCACGCCGG AGGCCAGAGG CCCGATCCGG GCAGCCCCGA GGGCCCTGCG 
CCACCTGCAC GCCGCGAGAG CCTCACCAAG AAAGCCAAGA GGTTCCTCGC CAACCTGGTG 
CCGCGCAACG CCAAGTTCTT CAAGCAGCGC TCCAGGTCGT GTCACGACCT CTCGGTGCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

REM2 ( NM_173527.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_775798.2 Homo sapiens RRAD and GEM like GTPase 2 (REM2), mRNA.

Price & Availability↑

CloneID	OHu07281
Clone ID Related Accession (Same CDS sequence)	NM_173527.2 , NM_173527.3
Accession Version	NM_173527.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1023bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Homo sapiens(human)
Product	GTP-binding protein REM 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL135998.6, AK096283.1 and BC035663.1. On Nov 22, 2018 this sequence version replaced NM_173527.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK096283.1, BC035663.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000267396.9/ ENSP00000267396.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCACACGG ACCTGGACAC AGACATGGAC ATGGACACAG AAACCACAGC ACTCTGCCCC 
TCTGGCAGCC GCCGGGCCTC CCCTCCAGGG ACGCCCACAC CAGAAGCAGA TGCCACGCTA 
CTAAAGAAGT CAGAGAAACT GTTGGCAGAG TTGGACCGGA GCGGGTTACC CTCTGCCCCT 
GGGGCCCCCA GACGAAGAGG CAGTATGCCT GTCCCCTACA AGCACCAGCT CCGGCGGGCC 
CAGGCTGTAG ATGAACTTGA CTGGCCACCT CAGGCCTCAT CCTCTGGCTC GTCTGACTCC 
TTGGGCTCAG GGGAGGCAGC CCCTGCTCAA AAGGATGGCA TCTTCAAGGT CATGCTAGTG 
GGGGAGAGCG GCGTGGGCAA GAGCACCCTA GCAGGCACTT TTGGTGGTCT CCAGGGAGAC 
AGTGCTCACG AACCGGAGAA CCCAGAGGAT ACCTATGAGA GACGCATCAT GGTGGATAAG 
GAGGAAGTGA CTCTAGTCGT TTATGACATC TGGGAACAGG GGGATGCAGG AGGGTGGCTG 
CGGGACCACT GCCTTCAGAC CGGGGACGCC TTTCTCATCG TCTTCTCAGT CACCGACCGA 
CGGAGTTTCT CCAAAGTTCC AGAGACCCTA CTTCGGCTCC GGGCTGGGAG GCCGCACCAC 
GACCTACCCG TTATCCTCGT TGGAAACAAG AGCGACTTGG CCCGCTCCCG GGAGGTATCA 
CTGGAGGAGG GCCGCCACCT GGCCGGGACG CTGAGCTGCA AGCACATCGA GACGTCGGCC 
GCACTGCACC ACAACACGAG GGAGCTCTTC GAGGGCGCGG TGCGCCAGAT CCGGCTGCGG 
CGGGGCCGAA ACCACGCCGG AGGCCAGAGG CCCGATCCGG GCAGCCCCGA GGGCCCTGCG 
CCACCTGCAC GCCGCGAGAG CCTCACCAAG AAAGCCAAGA GGTTCCTCGC CAACCTGGTG 
CCGCGCAACG CCAAGTTCTT CAAGCAGCGC TCCAGGTCGT GTCACGACCT CTCGGTGCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_775798.2
CDS	67..1089
Translation	MHTDLDTDMDMDTETTALCPSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVGKSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL

Target ORF information:

RefSeq Version	NM_173527.3
Organism	Homo sapiens(human)
Definition	Homo sapiens RRAD and GEM like GTPase 2 (REM2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_173527.3

ORF Insert Sequence:

ATGCACACGG ACCTGGACAC AGACATGGAC ATGGACACAG AAACCACAGC ACTCTGCCCC 
TCTGGCAGCC GCCGGGCCTC CCCTCCAGGG ACGCCCACAC CAGAAGCAGA TGCCACGCTA 
CTAAAGAAGT CAGAGAAACT GTTGGCAGAG TTGGACCGGA GCGGGTTACC CTCTGCCCCT 
GGGGCCCCCA GACGAAGAGG CAGTATGCCT GTCCCCTACA AGCACCAGCT CCGGCGGGCC 
CAGGCTGTAG ATGAACTTGA CTGGCCACCT CAGGCCTCAT CCTCTGGCTC GTCTGACTCC 
TTGGGCTCAG GGGAGGCAGC CCCTGCTCAA AAGGATGGCA TCTTCAAGGT CATGCTAGTG 
GGGGAGAGCG GCGTGGGCAA GAGCACCCTA GCAGGCACTT TTGGTGGTCT CCAGGGAGAC 
AGTGCTCACG AACCGGAGAA CCCAGAGGAT ACCTATGAGA GACGCATCAT GGTGGATAAG 
GAGGAAGTGA CTCTAGTCGT TTATGACATC TGGGAACAGG GGGATGCAGG AGGGTGGCTG 
CGGGACCACT GCCTTCAGAC CGGGGACGCC TTTCTCATCG TCTTCTCAGT CACCGACCGA 
CGGAGTTTCT CCAAAGTTCC AGAGACCCTA CTTCGGCTCC GGGCTGGGAG GCCGCACCAC 
GACCTACCCG TTATCCTCGT TGGAAACAAG AGCGACTTGG CCCGCTCCCG GGAGGTATCA 
CTGGAGGAGG GCCGCCACCT GGCCGGGACG CTGAGCTGCA AGCACATCGA GACGTCGGCC 
GCACTGCACC ACAACACGAG GGAGCTCTTC GAGGGCGCGG TGCGCCAGAT CCGGCTGCGG 
CGGGGCCGAA ACCACGCCGG AGGCCAGAGG CCCGATCCGG GCAGCCCCGA GGGCCCTGCG 
CCACCTGCAC GCCGCGAGAG CCTCACCAAG AAAGCCAAGA GGTTCCTCGC CAACCTGGTG 
CCGCGCAACG CCAAGTTCTT CAAGCAGCGC TCCAGGTCGT GTCACGACCT CTCGGTGCTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

REM2 ( XM_005267383.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005267440.1 Homo sapiens RRAD and GEM like GTPase 2 (REM2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu47565
Clone ID Related Accession (Same CDS sequence)	XM_005267383.3
Accession Version	XM_005267383.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	GTP-binding protein REM 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005267383.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACACGG ACCTGGACAC AGACATGGAC ATGGACACAG AAACCACAGC ACTCTGCCCC 
TCTGGCAGCC GCCGGGCCTC CCCTCCAGGG ACGCCCACAC CAGAAGCAGA TGCCACGCTA 
CTAAAGAAGT CAGAGAAACT GTTGGCAGAG TTGGACCGGA GCGGGTTACC CTCTGCCCCT 
GGGGCCCCCA GACGAAGAGG CAGTATGCCT GTCCCCTACA AGCACCAGCT CCGGCGGGCC 
CAGGCTGTAG ATGAACTTGA CTGGCCACCT CAGGCCTCAT CCTCTGGCTC GTCTGACTCC 
TTGGGCTCAG GGGAGGCAGC CCCTGCTCAA AAGGATGGCA TCTTCAAGGT CATGCTAGTG 
GGGGAGAGCG GCGTGGGCAA GAGCACCCTA GCAGGCACTT TTGGTGGTCT CCAGGGAGAC 
AGTGCTCACG AACCGGAGAA CCCAGCAGAG GATACCTATG AGAGACGCAT CATGGTGGAT 
AAGGAGGAAG TGACTCTAGT CGTTTATGAC ATCTGGGAAC AGGGGGATGC AGGAGGGTGG 
CTGCGGGACC ACTGCCTTCA GACCGGGGAC GCCTTTCTCA TCGTCTTCTC AGTCACCGAC 
CGACGGAGTT TCTCCAAAGT TCCAGAGACC CTACTTCGGC TCCGGGCTGG GAGGCCGCAC 
CACGACCTAC CCGTTATCCT CGTTGGAAAC AAGAGCGACT TGGCCCGCTC CCGGGAGGTA 
TCACTGGAGG AGGGCCGCCA CCTGGCCGGG ACGCTGAGCT GCAAGCACAT CGAGACGTCG 
GCCGCACTGC ACCACAACAC GAGGGAGCTC TTCGAGGGCG CGGTGCGCCA GATCCGGCTG 
CGGCGGGGCC GAAACCACGC CGGAGGCCAG AGGCCCGATC CGGGCAGCCC CGAGGGCCCT 
GCGCCACCTG CACGCCGCGA GAGCCTCACC AAGAAAGCCA AGAGGTTCCT CGCCAACCTG 
GTGCCGCGCA ACGCCAAGTT CTTCAAGCAG CGCTCCAGGT CGTGTCACGA CCTCTCGGTG 
CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005267440.1
CDS	124..1149
Translation	MHTDLDTDMDMDTETTALCPSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVGKSTLAGTFGGLQGDSAHEPENPAEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL

Target ORF information:

RefSeq Version	XM_005267383.3
Organism	Homo sapiens(human)
Definition	Homo sapiens RRAD and GEM like GTPase 2 (REM2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005267383.3

ORF Insert Sequence:

ATGCACACGG ACCTGGACAC AGACATGGAC ATGGACACAG AAACCACAGC ACTCTGCCCC 
TCTGGCAGCC GCCGGGCCTC CCCTCCAGGG ACGCCCACAC CAGAAGCAGA TGCCACGCTA 
CTAAAGAAGT CAGAGAAACT GTTGGCAGAG TTGGACCGGA GCGGGTTACC CTCTGCCCCT 
GGGGCCCCCA GACGAAGAGG CAGTATGCCT GTCCCCTACA AGCACCAGCT CCGGCGGGCC 
CAGGCTGTAG ATGAACTTGA CTGGCCACCT CAGGCCTCAT CCTCTGGCTC GTCTGACTCC 
TTGGGCTCAG GGGAGGCAGC CCCTGCTCAA AAGGATGGCA TCTTCAAGGT CATGCTAGTG 
GGGGAGAGCG GCGTGGGCAA GAGCACCCTA GCAGGCACTT TTGGTGGTCT CCAGGGAGAC 
AGTGCTCACG AACCGGAGAA CCCAGCAGAG GATACCTATG AGAGACGCAT CATGGTGGAT 
AAGGAGGAAG TGACTCTAGT CGTTTATGAC ATCTGGGAAC AGGGGGATGC AGGAGGGTGG 
CTGCGGGACC ACTGCCTTCA GACCGGGGAC GCCTTTCTCA TCGTCTTCTC AGTCACCGAC 
CGACGGAGTT TCTCCAAAGT TCCAGAGACC CTACTTCGGC TCCGGGCTGG GAGGCCGCAC 
CACGACCTAC CCGTTATCCT CGTTGGAAAC AAGAGCGACT TGGCCCGCTC CCGGGAGGTA 
TCACTGGAGG AGGGCCGCCA CCTGGCCGGG ACGCTGAGCT GCAAGCACAT CGAGACGTCG 
GCCGCACTGC ACCACAACAC GAGGGAGCTC TTCGAGGGCG CGGTGCGCCA GATCCGGCTG 
CGGCGGGGCC GAAACCACGC CGGAGGCCAG AGGCCCGATC CGGGCAGCCC CGAGGGCCCT 
GCGCCACCTG CACGCCGCGA GAGCCTCACC AAGAAAGCCA AGAGGTTCCT CGCCAACCTG 
GTGCCGCGCA ACGCCAAGTT CTTCAAGCAG CGCTCCAGGT CGTGTCACGA CCTCTCGGTG 
CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

REM2 ( XM_011536518.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534820.1 Homo sapiens RRAD and GEM like GTPase 2 (REM2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu77110
Clone ID Related Accession (Same CDS sequence)	XM_011536518.2
Accession Version	XM_011536518.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	GTP-binding protein REM 2 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011536518.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAACTC CAGTTCAGGC TTCTGGAGAC TTTAGTGTAA GAGGTCAGGC CAGACATTCT 
CAGTTCCTTC TGGGTAATGG TCATCAAGTG GGTGTAGCTG GGCCTCTGAT ACTGGAACAG 
CCTGGATTGA GCCTTCTGCA TATGGTTGAG CATATCCCAC TCATAGCTTC CTTTTCTTTG 
CCCTCCCATT TTATTTTAGA AGCAGATGCC ACGCTACTAA AGAAGTCAGA GAAACTGTTG 
GCAGAGTTGG ACCGGAGCGG GTTACCCTCT GCCCCTGGGG CCCCCAGACG AAGAGGCAGT 
ATGCCTGTCC CCTACAAGCA CCAGCTCCGG CGGGCCCAGG CTGTAGATGA ACTTGACTGG 
CCACCTCAGG CCTCATCCTC TGGCTCGTCT GACTCCTTGG GCTCAGGGGA GGCAGCCCCT 
GCTCAAAAGG ATGGCATCTT CAAGGTCATG CTAGTGGGGG AGAGCGGCGT GGGCAAGAGC 
ACCCTAGCAG GCACTTTTGG TGGTCTCCAG GGAGACAGTG CTCACGAACC GGAGAACCCA 
GCAGAGGATA CCTATGAGAG ACGCATCATG GTGGATAAGG AGGAAGTGAC TCTAGTCGTT 
TATGACATCT GGGAACAGGG GGATGCAGGA GGGTGGCTGC GGGACCACTG CCTTCAGACC 
GGGGACGCCT TTCTCATCGT CTTCTCAGTC ACCGACCGAC GGAGTTTCTC CAAAGTTCCA 
GAGACCCTAC TTCGGCTCCG GGCTGGGAGG CCGCACCACG ACCTACCCGT TATCCTCGTT 
GGAAACAAGA GCGACTTGGC CCGCTCCCGG GAGAGGGCCG CCACCTGGCC GGGACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534820.1
CDS	1177..2016
Translation	MSTPVQASGDFSVRGQARHSQFLLGNGHQVGVAGPLILEQPGLSLLHMVEHIPLIASFSLPSHFILEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVGKSTLAGTFGGLQGDSAHEPENPAEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSRERAATWPGR

Target ORF information:

RefSeq Version	XM_011536518.2
Organism	Homo sapiens(human)
Definition	Homo sapiens RRAD and GEM like GTPase 2 (REM2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011536518.2

ORF Insert Sequence:

ATGTCAACTC CAGTTCAGGC TTCTGGAGAC TTTAGTGTAA GAGGTCAGGC CAGACATTCT 
CAGTTCCTTC TGGGTAATGG TCATCAAGTG GGTGTAGCTG GGCCTCTGAT ACTGGAACAG 
CCTGGATTGA GCCTTCTGCA TATGGTTGAG CATATCCCAC TCATAGCTTC CTTTTCTTTG 
CCCTCCCATT TTATTTTAGA AGCAGATGCC ACGCTACTAA AGAAGTCAGA GAAACTGTTG 
GCAGAGTTGG ACCGGAGCGG GTTACCCTCT GCCCCTGGGG CCCCCAGACG AAGAGGCAGT 
ATGCCTGTCC CCTACAAGCA CCAGCTCCGG CGGGCCCAGG CTGTAGATGA ACTTGACTGG 
CCACCTCAGG CCTCATCCTC TGGCTCGTCT GACTCCTTGG GCTCAGGGGA GGCAGCCCCT 
GCTCAAAAGG ATGGCATCTT CAAGGTCATG CTAGTGGGGG AGAGCGGCGT GGGCAAGAGC 
ACCCTAGCAG GCACTTTTGG TGGTCTCCAG GGAGACAGTG CTCACGAACC GGAGAACCCA 
GCAGAGGATA CCTATGAGAG ACGCATCATG GTGGATAAGG AGGAAGTGAC TCTAGTCGTT 
TATGACATCT GGGAACAGGG GGATGCAGGA GGGTGGCTGC GGGACCACTG CCTTCAGACC 
GGGGACGCCT TTCTCATCGT CTTCTCAGTC ACCGACCGAC GGAGTTTCTC CAAAGTTCCA 
GAGACCCTAC TTCGGCTCCG GGCTGGGAGG CCGCACCACG ACCTACCCGT TATCCTCGTT 
GGAAACAAGA GCGACTTGGC CCGCTCCCGG GAGAGGGCCG CCACCTGGCC GGGACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

REM2 ( XM_017021058.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016876547.1 Homo sapiens RRAD and GEM like GTPase 2 (REM2), transcript variant X1, mRNA.

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CloneID	OHu84806
Clone ID Related Accession (Same CDS sequence)	XM_017021058.1
Accession Version	XM_017021058.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	GTP-binding protein REM 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAACTC CAGTTCAGGC TTCTGGAGAC TTTAGTGTAA GAGGTCAGGC CAGACATTCT 
CAGTTCCTTC TGGGTAATGG TCATCAAGTG GGTGTAGCTG GGCCTCTGAT ACTGGAACAG 
CCTGGATTGA GCCTTCTGCA TATGGTTGAG CATATCCCAC TCATAGCTTC CTTTTCTTTG 
CCCTCCCATT TTATTTTAGA AGCAGATGCC ACGCTACTAA AGAAGTCAGA GAAACTGTTG 
GCAGAGTTGG ACCGGAGCGG GTTACCCTCT GCCCCTGGGG CCCCCAGACG AAGAGGCAGT 
ATGCCTGTCC CCTACAAGCA CCAGCTCCGG CGGGCCCAGG CTGTAGATGA ACTTGACTGG 
CCACCTCAGG CCTCATCCTC TGGCTCGTCT GACTCCTTGG GCTCAGGGGA GGCAGCCCCT 
GCTCAAAAGG ATGGCATCTT CAAGGTCATG CTAGTGGGGG AGAGCGGCGT GGGCAAGAGC 
ACCCTAGCAG GCACTTTTGG TGGTCTCCAG GGAGACAGTG CTCACGAACC GGAGAACCCA 
GCAGAGGATA CCTATGAGAG ACGCATCATG GTGGATAAGG AGGAAGTGAC TCTAGTCGTT 
TATGACATCT GGGAACAGGG GGATGCAGGA GGGTGGCTGC GGGACCACTG CCTTCAGACC 
GGGGACGCCT TTCTCATCGT CTTCTCAGTC ACCGACCGAC GGAGTTTCTC CAAAGTTCCA 
GAGACCCTAC TTCGGCTCCG GGCTGGGAGG CCGCACCACG ACCTACCCGT TATCCTCGTT 
GGAAACAAGA GCGACTTGGC CCGCTCCCGG GAGGTATCAC TGGAGGAGGG CCGCCACCTG 
GCCGGGACGC TGAGCTGCAA GCACATCGAG ACGTCGGCCG CACTGCACCA CAACACGAGG 
GAGCTCTTCG AGGGCGCGGT GCGCCAGATC CGGCTGCGGC GGGGCCGAAA CCACGCCGGA 
GGCCAGAGGC CCGATCCGGG CAGCCCCGAG GGCCCTGCGC CACCTGCACG CCGCGAGAGC 
CTCACCAAGA AAGCCAAGAG GTTCCTCGCC AACCTGGTGC CGCGCAACGC CAAGTTCTTC 
AAGCAGCGCT CCAGGTCGTG TCACGACCTC TCGGTGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016876547.1
CDS	1177..2298
Translation	MSTPVQASGDFSVRGQARHSQFLLGNGHQVGVAGPLILEQPGLSLLHMVEHIPLIASFSLPSHFILEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVGKSTLAGTFGGLQGDSAHEPENPAEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL

Target ORF information:

RefSeq Version	XM_017021058.1
Organism	Homo sapiens(human)
Definition	Homo sapiens RRAD and GEM like GTPase 2 (REM2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017021058.1

ORF Insert Sequence:

ATGTCAACTC CAGTTCAGGC TTCTGGAGAC TTTAGTGTAA GAGGTCAGGC CAGACATTCT 
CAGTTCCTTC TGGGTAATGG TCATCAAGTG GGTGTAGCTG GGCCTCTGAT ACTGGAACAG 
CCTGGATTGA GCCTTCTGCA TATGGTTGAG CATATCCCAC TCATAGCTTC CTTTTCTTTG 
CCCTCCCATT TTATTTTAGA AGCAGATGCC ACGCTACTAA AGAAGTCAGA GAAACTGTTG 
GCAGAGTTGG ACCGGAGCGG GTTACCCTCT GCCCCTGGGG CCCCCAGACG AAGAGGCAGT 
ATGCCTGTCC CCTACAAGCA CCAGCTCCGG CGGGCCCAGG CTGTAGATGA ACTTGACTGG 
CCACCTCAGG CCTCATCCTC TGGCTCGTCT GACTCCTTGG GCTCAGGGGA GGCAGCCCCT 
GCTCAAAAGG ATGGCATCTT CAAGGTCATG CTAGTGGGGG AGAGCGGCGT GGGCAAGAGC 
ACCCTAGCAG GCACTTTTGG TGGTCTCCAG GGAGACAGTG CTCACGAACC GGAGAACCCA 
GCAGAGGATA CCTATGAGAG ACGCATCATG GTGGATAAGG AGGAAGTGAC TCTAGTCGTT 
TATGACATCT GGGAACAGGG GGATGCAGGA GGGTGGCTGC GGGACCACTG CCTTCAGACC 
GGGGACGCCT TTCTCATCGT CTTCTCAGTC ACCGACCGAC GGAGTTTCTC CAAAGTTCCA 
GAGACCCTAC TTCGGCTCCG GGCTGGGAGG CCGCACCACG ACCTACCCGT TATCCTCGTT 
GGAAACAAGA GCGACTTGGC CCGCTCCCGG GAGGTATCAC TGGAGGAGGG CCGCCACCTG 
GCCGGGACGC TGAGCTGCAA GCACATCGAG ACGTCGGCCG CACTGCACCA CAACACGAGG 
GAGCTCTTCG AGGGCGCGGT GCGCCAGATC CGGCTGCGGC GGGGCCGAAA CCACGCCGGA 
GGCCAGAGGC CCGATCCGGG CAGCCCCGAG GGCCCTGCGC CACCTGCACG CCGCGAGAGC 
CTCACCAAGA AAGCCAAGAG GTTCCTCGCC AACCTGGTGC CGCGCAACGC CAAGTTCTTC 
AAGCAGCGCT CCAGGTCGTG TCACGACCTC TCGGTGCTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

REM2 ( XM_017021059.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016876548.1 Homo sapiens RRAD and GEM like GTPase 2 (REM2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu84807
Clone ID Related Accession (Same CDS sequence)	XM_017021059.1
Accession Version	XM_017021059.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	GTP-binding protein REM 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAACTC CAGTTCAGGC TTCTGGAGAC TTTAGTGTAA GAGGTCAGGC CAGACATTCT 
CAGTTCCTTC TGGGTAATGG TCATCAAGTG GGTGTAGCTG GGCCTCTGAT ACTGGAACAG 
CCTGGATTGA GCCTTCTGCA TATGGTTGAG CATATCCCAC TCATAGCTTC CTTTTCTTTG 
CCCTCCCATT TTATTTTAGA AGCAGATGCC ACGCTACTAA AGAAGTCAGA GAAACTGTTG 
GCAGAGTTGG ACCGGAGCGG GTTACCCTCT GCCCCTGGGG CCCCCAGACG AAGAGGCAGT 
ATGCCTGTCC CCTACAAGCA CCAGCTCCGG CGGGCCCAGG CTGTAGATGA ACTTGACTGG 
CCACCTCAGG CCTCATCCTC TGGCTCGTCT GACTCCTTGG GCTCAGGGGA GGCAGCCCCT 
GCTCAAAAGG ATGGCATCTT CAAGGTCATG CTAGTGGGGG AGAGCGGCGT GGGCAAGAGC 
ACCCTAGCAG GCACTTTTGG TGGTCTCCAG GGAGACAGTG CTCACGAACC GGAGAACCCA 
GAGGATACCT ATGAGAGACG CATCATGGTG GATAAGGAGG AAGTGACTCT AGTCGTTTAT 
GACATCTGGG AACAGGGGGA TGCAGGAGGG TGGCTGCGGG ACCACTGCCT TCAGACCGGG 
GACGCCTTTC TCATCGTCTT CTCAGTCACC GACCGACGGA GTTTCTCCAA AGTTCCAGAG 
ACCCTACTTC GGCTCCGGGC TGGGAGGCCG CACCACGACC TACCCGTTAT CCTCGTTGGA 
AACAAGAGCG ACTTGGCCCG CTCCCGGGAG GTATCACTGG AGGAGGGCCG CCACCTGGCC 
GGGACGCTGA GCTGCAAGCA CATCGAGACG TCGGCCGCAC TGCACCACAA CACGAGGGAG 
CTCTTCGAGG GCGCGGTGCG CCAGATCCGG CTGCGGCGGG GCCGAAACCA CGCCGGAGGC 
CAGAGGCCCG ATCCGGGCAG CCCCGAGGGC CCTGCGCCAC CTGCACGCCG CGAGAGCCTC 
ACCAAGAAAG CCAAGAGGTT CCTCGCCAAC CTGGTGCCGC GCAACGCCAA GTTCTTCAAG 
CAGCGCTCCA GGTCGTGTCA CGACCTCTCG GTGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016876548.1
CDS	1177..2295
Translation	MSTPVQASGDFSVRGQARHSQFLLGNGHQVGVAGPLILEQPGLSLLHMVEHIPLIASFSLPSHFILEADATLLKKSEKLLAELDRSGLPSAPGAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLVGESGVGKSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWLRDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPAPPARRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL

Target ORF information:

RefSeq Version	XM_017021059.1
Organism	Homo sapiens(human)
Definition	Homo sapiens RRAD and GEM like GTPase 2 (REM2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017021059.1

ORF Insert Sequence:

ATGTCAACTC CAGTTCAGGC TTCTGGAGAC TTTAGTGTAA GAGGTCAGGC CAGACATTCT 
CAGTTCCTTC TGGGTAATGG TCATCAAGTG GGTGTAGCTG GGCCTCTGAT ACTGGAACAG 
CCTGGATTGA GCCTTCTGCA TATGGTTGAG CATATCCCAC TCATAGCTTC CTTTTCTTTG 
CCCTCCCATT TTATTTTAGA AGCAGATGCC ACGCTACTAA AGAAGTCAGA GAAACTGTTG 
GCAGAGTTGG ACCGGAGCGG GTTACCCTCT GCCCCTGGGG CCCCCAGACG AAGAGGCAGT 
ATGCCTGTCC CCTACAAGCA CCAGCTCCGG CGGGCCCAGG CTGTAGATGA ACTTGACTGG 
CCACCTCAGG CCTCATCCTC TGGCTCGTCT GACTCCTTGG GCTCAGGGGA GGCAGCCCCT 
GCTCAAAAGG ATGGCATCTT CAAGGTCATG CTAGTGGGGG AGAGCGGCGT GGGCAAGAGC 
ACCCTAGCAG GCACTTTTGG TGGTCTCCAG GGAGACAGTG CTCACGAACC GGAGAACCCA 
GAGGATACCT ATGAGAGACG CATCATGGTG GATAAGGAGG AAGTGACTCT AGTCGTTTAT 
GACATCTGGG AACAGGGGGA TGCAGGAGGG TGGCTGCGGG ACCACTGCCT TCAGACCGGG 
GACGCCTTTC TCATCGTCTT CTCAGTCACC GACCGACGGA GTTTCTCCAA AGTTCCAGAG 
ACCCTACTTC GGCTCCGGGC TGGGAGGCCG CACCACGACC TACCCGTTAT CCTCGTTGGA 
AACAAGAGCG ACTTGGCCCG CTCCCGGGAG GTATCACTGG AGGAGGGCCG CCACCTGGCC 
GGGACGCTGA GCTGCAAGCA CATCGAGACG TCGGCCGCAC TGCACCACAA CACGAGGGAG 
CTCTTCGAGG GCGCGGTGCG CCAGATCCGG CTGCGGCGGG GCCGAAACCA CGCCGGAGGC 
CAGAGGCCCG ATCCGGGCAG CCCCGAGGGC CCTGCGCCAC CTGCACGCCG CGAGAGCCTC 
ACCAAGAAAG CCAAGAGGTT CCTCGCCAAC CTGGTGCCGC GCAACGCCAA GTTCTTCAAG 
CAGCGCTCCA GGTCGTGTCA CGACCTCTCG GTGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

A loss-of-function analysis reveals that endogenous Rem2 promotes functional glutamatergic synapse formation and restricts dendritic complexity.
PloS one8(8)e74751(2013)
Moore AR,Ghiretti AE,Paradis S

Activity-dependent subcellular cotrafficking of the small GTPase Rem2 and Ca2+/CaM-dependent protein kinase II?.
PloS one7(7)e41185(2012)
Flynn R,Labrie-Dion E,Bernier N,Colicos MA,De Koninck P,Zamponi GW

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REM2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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