Rem2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rem2
Entrez Gene ID	140743
Full Name	rad and gem related GTP binding protein 2
Synonyms	AW411893
General protein information	Preferred Names rad and gem related GTP binding protein 2 Names GTP-binding protein REM 2 rad and Gem-like GTP-binding protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 14 Map Location: 14\|14 C2

mRNA and Protein(s)

mRNA	Protein	Name
NM_080726.3	NP_542764.2	GTP-binding protein REM 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	REM2	NP_775798.2
Canis lupus familiaris (dog)	REM2	XP_005623273.1
Bos taurus (cattle)	REM2	NP_001179637.1
Xenopus tropicalis (tropical clawed frog)	rem2	XP_002941555.1
Pan troglodytes (chimpanzee)	REM2	XP_522796.2
	LOC712572	XP_001100692.1
Mus musculus (house mouse)	Rem2	NP_542764.2
Rattus norvegicus (Norway rat)	Rem2	NP_073176.2

Gene Ontology
Bibliography

Related articles in PubMed

Rem2 signaling affects neuronal structure and function in part by regulation of gene expression.
Kenny K, Royer L, Moore AR, Chen X, Marr MT 2nd, Paradis S
Molecular and cellular neurosciences85190-201(2017 Dec)

Rem2, a member of the RGK family of small GTPases, is enriched in nuclei of the basal ganglia.
Liput DJ, Lu VB, Davis MI, Puhl HL, Ikeda SR
Scientific reports625137(2016 04)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Voltage dependant calcium channels blockade by Rem2 is likely to be controlled by both the localized concentration of membrane phosphorylated phosphatidylinositide lipids and direct 14-3-3 binding to the Rem2 C-terminus.
Title: Analysis of the Rem2 - voltage dependant calcium channel beta subunit interaction and Rem2 interaction with phosphorylated phosphatidylinositide lipids.

Nuclear localization of RGK proteins (Rad, Rem, and Rem2) contributes to the suppression of RGK-mediated cell shape remodeling.
Title: Nuclear localization of endogenous RGK proteins and modulation of cell shape remodeling by regulated nuclear transport.

The following Rem2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rem2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09741	NM_080726.3 Latest version!	Mus musculus rad and gem related GTP binding protein 2 (Rem2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rem2 ( NM_080726.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_542764.2 Mus musculus rad and gem related GTP binding protein 2 (Rem2), mRNA.

Price & Availability↑

CloneID	OMu09741
Clone ID Related Accession (Same CDS sequence)	NM_080726.3
Accession Version	NM_080726.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	GTP-binding protein REM 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK090165.1. On Apr 6, 2007 this sequence version replaced NM_080726.2. ##Evidence-Data-START## Transcript exon combination :: AK090165.1, BC018219.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCACACGG ACCTTGACAC CGACATGGAC ATGGACACAG AAACCGTAGC ACTTTGTTCT 
TCCAGCAGCC GCCAGGCCTC CCCACTGGGG ACACCCACAC CAGAAGCAGA TACTACACTT 
CTGAAACAGA AGCCAGAGAA ACTGTTAGCA GAGTTGGACC TGAGCGGGCC TCCTCCTGCT 
CCTGGGGTCC CCAGACGAAG AGGAAGCATG CCCGTGCCCT ACAAACACCA GCTGCGGCGG 
GCCCAAGCTG TAGATGAACT TGACTGGCCA CCCCAGGCCT CCCCCTCTGG CTCCTCTGAC 
TCCTTGGGCT CAGGGGAGGC AGCCCTTACC CAAAAAGATG GCGTCTTTAA GGTCATGCTC 
GTGGGGGAGA GTGGCGTGGG CAAGAGCACT CTAGCGGGCA CTTTTGGAGG TCTCCAGGGA 
GACCATGCTC ACGAGATGGA GAACTCAGAG GACACCTATG AGAGACGGAT CATGGTGGAC 
AAAGAAGAAG TGACTTTAAT TGTTTATGAC ATCTGGGAAC AGGGAGATGC AGGAGGATGG 
CTGCAGGATC ACTGCCTTCA GACGGGGGAT GCCTTTCTCA TCGTCTTCTC AGTGACAGAT 
CGACGAAGCT TCTCTAAAGT TCCAGAAACC CTTCTTCGGC TCCGGGCTGG GAGGCCCCAC 
CATGACCTAC CTGTCATCCT TGTTGGAAAT AAGAGTGACC TGGCCCGCTC CCGGGAGGTA 
TCACTGGAGG AGGGTCGCCA TCTGGCTGGG ACGCTGAGCT GCAAGCACAT CGAGACGTCG 
GCCGCTCTCC ACCACAACAC TCGTGAGCTC TTCGAGGGTG CTGTGCGTCA GATCAGGCTG 
CGGCGGGGCC GGGGTCATGC CGGGGGCCAG CGACCCGAAC CTAGCAGCCC GGACGGCCCC 
GCGCCGCCTA CGCGCCGTGA GAGCCTCACC AAGAAAGCTA AGCGCTTCCT CGCCAACCTG 
GTGCCGCGCA ACGCTAAGTT CTTCAAGCAA CGCTCCAGGT CATGTCACGA CCTCTCTGTG 
CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_542764.2
CDS	173..1198
Translation	MHTDLDTDMDMDTETVALCSSSSRQASPLGTPTPEADTTLLKQKPEKLLAELDLSGPPPAPGVPRRRGSMPVPYKHQLRRAQAVDELDWPPQASPSGSSDSLGSGEAALTQKDGVFKVMLVGESGVGKSTLAGTFGGLQGDHAHEMENSEDTYERRIMVDKEEVTLIVYDIWEQGDAGGWLQDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVSLEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRGHAGGQRPEPSSPDGPAPPTRRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL

Target ORF information:

RefSeq Version	NM_080726.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus rad and gem related GTP binding protein 2 (Rem2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080726.3

ORF Insert Sequence:

ATGCACACGG ACCTTGACAC CGACATGGAC ATGGACACAG AAACCGTAGC ACTTTGTTCT 
TCCAGCAGCC GCCAGGCCTC CCCACTGGGG ACACCCACAC CAGAAGCAGA TACTACACTT 
CTGAAACAGA AGCCAGAGAA ACTGTTAGCA GAGTTGGACC TGAGCGGGCC TCCTCCTGCT 
CCTGGGGTCC CCAGACGAAG AGGAAGCATG CCCGTGCCCT ACAAACACCA GCTGCGGCGG 
GCCCAAGCTG TAGATGAACT TGACTGGCCA CCCCAGGCCT CCCCCTCTGG CTCCTCTGAC 
TCCTTGGGCT CAGGGGAGGC AGCCCTTACC CAAAAAGATG GCGTCTTTAA GGTCATGCTC 
GTGGGGGAGA GTGGCGTGGG CAAGAGCACT CTAGCGGGCA CTTTTGGAGG TCTCCAGGGA 
GACCATGCTC ACGAGATGGA GAACTCAGAG GACACCTATG AGAGACGGAT CATGGTGGAC 
AAAGAAGAAG TGACTTTAAT TGTTTATGAC ATCTGGGAAC AGGGAGATGC AGGAGGATGG 
CTGCAGGATC ACTGCCTTCA GACGGGGGAT GCCTTTCTCA TCGTCTTCTC AGTGACAGAT 
CGACGAAGCT TCTCTAAAGT TCCAGAAACC CTTCTTCGGC TCCGGGCTGG GAGGCCCCAC 
CATGACCTAC CTGTCATCCT TGTTGGAAAT AAGAGTGACC TGGCCCGCTC CCGGGAGGTA 
TCACTGGAGG AGGGTCGCCA TCTGGCTGGG ACGCTGAGCT GCAAGCACAT CGAGACGTCG 
GCCGCTCTCC ACCACAACAC TCGTGAGCTC TTCGAGGGTG CTGTGCGTCA GATCAGGCTG 
CGGCGGGGCC GGGGTCATGC CGGGGGCCAG CGACCCGAAC CTAGCAGCCC GGACGGCCCC 
GCGCCGCCTA CGCGCCGTGA GAGCCTCACC AAGAAAGCTA AGCGCTTCCT CGCCAACCTG 
GTGCCGCGCA ACGCTAAGTT CTTCAAGCAA CGCTCCAGGT CATGTCACGA CCTCTCTGTG 
CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Rem2 signaling affects neuronal structure and function in part by regulation of gene expression.
Molecular and cellular neurosciences85190-201(2017 Dec)
Kenny K,Royer L,Moore AR,Chen X,Marr MT 2nd,Paradis S

Rem2, a member of the RGK family of small GTPases, is enriched in nuclei of the basal ganglia.
Scientific reports625137(2016 04)
Liput DJ,Lu VB,Davis MI,Puhl HL,Ikeda SR

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H

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Rem2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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FAX

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