CRYAB gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
NM_001330379.1	NP_001317308.1	alpha-crystallin B chain isoform 2
NM_001289808.2	NP_001276737.1	alpha-crystallin B chain isoform 1
NM_001289808.1	NP_001276737.1	alpha-crystallin B chain isoform 1
NM_001289807.1	NP_001276736.1	alpha-crystallin B chain isoform 1
NM_001368245.1	NP_001355174.1	alpha-crystallin B chain isoform 1
NM_001885.2	NP_001876.1	alpha-crystallin B chain isoform 1
XM_011542608.1	XP_011540910.1	alpha-crystallin B chain isoform X1
NM_001885.3	NP_001876.1	alpha-crystallin B chain isoform 1
NM_001368246.1	NP_001355175.1	alpha-crystallin B chain isoform 2

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16676	NM_001885.3 Latest version!	Homo sapiens crystallin alpha B (CRYAB), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu16676	NM_001289808.2 Latest version!	Homo sapiens crystallin alpha B (CRYAB), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu16676	NM_001368245.1 Latest version!	Homo sapiens crystallin alpha B (CRYAB), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu16676	NM_001289807.1 Latest version!	Homo sapiens crystallin alpha B (CRYAB), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu16676	XM_011542608.1 Latest version!	Homo sapiens crystallin alpha B (CRYAB), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu57086	NM_001368246.1 Latest version!	Homo sapiens crystallin alpha B (CRYAB), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu57086	NM_001330379.1 Latest version!	Homo sapiens crystallin alpha B (CRYAB), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
View Old Accession Versions >>
OHu16676	NM_001289808.1	Homo sapiens crystallin alpha B (CRYAB), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu16676	NM_001885.2	Homo sapiens crystallin alpha B (CRYAB), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

CRYAB ( NM_001289808.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276737.1 Homo sapiens crystallin alpha B (CRYAB), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16676
Clone ID Related Accession (Same CDS sequence)	NM_001289808.2 , NM_001289808.1 , NM_001289807.1 , NM_001368245.1 , NM_001885.2 , XM_011542608.1 , NM_001885.3
Accession Version	NM_001289808.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	alpha-crystallin B chain isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BE076509.1, BM721803.1, BC007008.1, BF339748.1 and AP000907.6. On May 17, 2019 this sequence version replaced NM_001289808.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC007008.1, BQ005860.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000650687.2/ ENSP00000499082.1 multifunctional gene product(s) :: PMID: 10217480 RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276737.1
CDS	47..574
Translation	MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK

Target ORF information:

RefSeq Version	NM_001289808.2
Organism	Homo sapiens(human)
Definition	Homo sapiens crystallin alpha B (CRYAB), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289808.2

ORF Insert Sequence:

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CRYAB ( NM_001289808.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276737.1 Homo sapiens crystallin alpha B (CRYAB), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16676
Clone ID Related Accession (Same CDS sequence)	NM_001289808.2 , NM_001289808.1 , NM_001289807.1 , NM_001368245.1 , NM_001885.2 , XM_011542608.1 , NM_001885.3
Accession Version	NM_001289808.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	alpha-crystallin B chain isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI548180.1, BE076509.1, BM721803.1, BC007008.1 and BF339748.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279859.3731.1, ERR279834.1258.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## multifunctional gene product(s) :: PMID: 10217480 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276737.1
CDS	303..830
Translation	MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK

Target ORF information:

RefSeq Version	NM_001289808.1
Organism	Homo sapiens(human)
Definition	Homo sapiens crystallin alpha B (CRYAB), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289808.1

ORF Insert Sequence:

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CRYAB ( NM_001289807.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001276736.1 Homo sapiens crystallin alpha B (CRYAB), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16676
Clone ID Related Accession (Same CDS sequence)	NM_001289808.2 , NM_001289808.1 , NM_001289807.1 , NM_001368245.1 , NM_001885.2 , XM_011542608.1 , NM_001885.3
Accession Version	NM_001289807.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	alpha-crystallin B chain isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB506606.1, BI759672.1, BM721803.1, BC007008.1 and BF339748.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI759672.1, SRR7410570.491597.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## multifunctional gene product(s) :: PMID: 10217480 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276736.1
CDS	274..801
Translation	MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK

Target ORF information:

RefSeq Version	NM_001289807.1
Organism	Homo sapiens(human)
Definition	Homo sapiens crystallin alpha B (CRYAB), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289807.1

ORF Insert Sequence:

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CRYAB ( NM_001368245.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001355174.1 Homo sapiens crystallin alpha B (CRYAB), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu16676
Clone ID Related Accession (Same CDS sequence)	NM_001289808.2 , NM_001289808.1 , NM_001289807.1 , NM_001368245.1 , NM_001885.2 , XM_011542608.1 , NM_001885.3
Accession Version	NM_001368245.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	alpha-crystallin B chain isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP000907.6. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.44348.1, BU556902.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154125, SAMEA2154361 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## multifunctional gene product(s) :: PMID: 10217480 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001355174.1
CDS	237..764
Translation	MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK

Target ORF information:

RefSeq Version	NM_001368245.1
Organism	Homo sapiens(human)
Definition	Homo sapiens crystallin alpha B (CRYAB), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001368245.1

ORF Insert Sequence:

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CRYAB ( NM_001885.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001876.1 Homo sapiens crystallin alpha B (CRYAB), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16676
Clone ID Related Accession (Same CDS sequence)	NM_001289808.2 , NM_001289808.1 , NM_001289807.1 , NM_001368245.1 , NM_001885.2 , XM_011542608.1 , NM_001885.3
Accession Version	NM_001885.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	alpha-crystallin B chain isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB506606.1, BM721803.1, BC007008.1 and BF339748.1. This sequence is a reference standard in the RefSeqGene project. On Jan 31, 2014 this sequence version replaced NM_001885.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279849.4838.1, ERR279842.9857.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## multifunctional gene product(s) :: PMID: 10217480 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001876.1
CDS	308..835
Translation	MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK

Target ORF information:

RefSeq Version	NM_001885.2
Organism	Homo sapiens(human)
Definition	Homo sapiens crystallin alpha B (CRYAB), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001885.2

ORF Insert Sequence:

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CRYAB ( NM_001885.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001876.1 Homo sapiens crystallin alpha B (CRYAB), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16676
Clone ID Related Accession (Same CDS sequence)	NM_001289808.2 , NM_001289808.1 , NM_001289807.1 , NM_001368245.1 , NM_001885.2 , XM_011542608.1 , NM_001885.3
Accession Version	NM_001885.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	alpha-crystallin B chain isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM721803.1, BC007008.1, BF339748.1 and AP000907.6. This sequence is a reference standard in the RefSeqGene project. On Jun 1, 2019 this sequence version replaced NM_001885.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.22038.1, SRR5189667.79928.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## multifunctional gene product(s) :: PMID: 10217480 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001876.1
CDS	256..783
Translation	MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK

Target ORF information:

RefSeq Version	NM_001885.3
Organism	Homo sapiens(human)
Definition	Homo sapiens crystallin alpha B (CRYAB), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001885.3

ORF Insert Sequence:

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CRYAB ( XM_011542608.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011540910.1 Homo sapiens crystallin alpha B (CRYAB), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu16676
Clone ID Related Accession (Same CDS sequence)	NM_001289808.2 , NM_001289808.1 , NM_001289807.1 , NM_001368245.1 , NM_001885.2 , XM_011542608.1 , NM_001885.3
Accession Version	XM_011542608.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	alpha-crystallin B chain isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011540910.1
CDS	289..816
Translation	MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK

Target ORF information:

RefSeq Version	XM_011542608.1
Organism	Homo sapiens(human)
Definition	Homo sapiens crystallin alpha B (CRYAB), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011542608.1

ORF Insert Sequence:

ATGGACATCG CCATCCACCA CCCCTGGATC CGCCGCCCCT TCTTTCCTTT CCACTCCCCC 
AGCCGCCTCT TTGACCAGTT CTTCGGAGAG CACCTGTTGG AGTCTGATCT TTTCCCGACG 
TCTACTTCCC TGAGTCCCTT CTACCTTCGG CCACCCTCCT TCCTGCGGGC ACCCAGCTGG 
TTTGACACTG GACTCTCAGA GATGCGCCTG GAGAAGGACA GGTTCTCTGT CAACCTGGAT 
GTGAAGCACT TCTCCCCAGA GGAACTCAAA GTTAAGGTGT TGGGAGATGT GATTGAGGTG 
CATGGAAAAC ATGAAGAGCG CCAGGATGAA CATGGTTTCA TCTCCAGGGA GTTCCACAGG 
AAATACCGGA TCCCAGCTGA TGTAGACCCT CTCACCATTA CTTCATCCCT GTCATCTGAT 
GGGGTCCTCA CTGTGAATGG ACCAAGGAAA CAGGTCTCTG GCCCTGAGCG CACCATTCCC 
ATCACCCGTG AAGAGAAGCC TGCTGTCACC GCAGCCCCCA AGAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CRYAB ( NM_001330379.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317308.1 Homo sapiens crystallin alpha B (CRYAB), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu57086
Clone ID Related Accession (Same CDS sequence)	NM_001330379.1 , NM_001368246.1
Accession Version	NM_001330379.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 327bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-22
Organism	Homo sapiens(human)
Product	alpha-crystallin B chain isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP000907.6, BQ437433.1 and BF339748.1. On Aug 29, 2016 this sequence version replaced XM_011542609.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ709037.1, BQ437433.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2151741, SAMN03267751 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## multifunctional gene product(s) :: PMID: 10217480 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCGCCTGG AGAAGGACAG GTTCTCTGTC AACCTGGATG TGAAGCACTT CTCCCCAGAG 
GAACTCAAAG TTAAGGTGTT GGGAGATGTG ATTGAGGTGC ATGGAAAACA TGAAGAGCGC 
CAGGATGAAC ATGGTTTCAT CTCCAGGGAG TTCCACAGGA AATACCGGAT CCCAGCTGAT 
GTAGACCCTC TCACCATTAC TTCATCCCTG TCATCTGATG GGGTCCTCAC TGTGAATGGA 
CCAAGGAAAC AGGTCTCTGG CCCTGAGCGC ACCATTCCCA TCACCCGTGA AGAGAAGCCT 
GCTGTCACCG CAGCCCCCAA GAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317308.1
CDS	84..410
Translation	MRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK

Target ORF information:

RefSeq Version	NM_001330379.1
Organism	Homo sapiens(human)
Definition	Homo sapiens crystallin alpha B (CRYAB), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330379.1

ORF Insert Sequence:

ATGCGCCTGG AGAAGGACAG GTTCTCTGTC AACCTGGATG TGAAGCACTT CTCCCCAGAG 
GAACTCAAAG TTAAGGTGTT GGGAGATGTG ATTGAGGTGC ATGGAAAACA TGAAGAGCGC 
CAGGATGAAC ATGGTTTCAT CTCCAGGGAG TTCCACAGGA AATACCGGAT CCCAGCTGAT 
GTAGACCCTC TCACCATTAC TTCATCCCTG TCATCTGATG GGGTCCTCAC TGTGAATGGA 
CCAAGGAAAC AGGTCTCTGG CCCTGAGCGC ACCATTCCCA TCACCCGTGA AGAGAAGCCT 
GCTGTCACCG CAGCCCCCAA GAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CRYAB ( NM_001368246.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001355175.1 Homo sapiens crystallin alpha B (CRYAB), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu57086
Clone ID Related Accession (Same CDS sequence)	NM_001330379.1 , NM_001368246.1
Accession Version	NM_001368246.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 327bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	alpha-crystallin B chain isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EB386544.1 and AP000907.6. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7410570.491736.1, SRR7410570.491589.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## multifunctional gene product(s) :: PMID: 10217480 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCGCCTGG AGAAGGACAG GTTCTCTGTC AACCTGGATG TGAAGCACTT CTCCCCAGAG 
GAACTCAAAG TTAAGGTGTT GGGAGATGTG ATTGAGGTGC ATGGAAAACA TGAAGAGCGC 
CAGGATGAAC ATGGTTTCAT CTCCAGGGAG TTCCACAGGA AATACCGGAT CCCAGCTGAT 
GTAGACCCTC TCACCATTAC TTCATCCCTG TCATCTGATG GGGTCCTCAC TGTGAATGGA 
CCAAGGAAAC AGGTCTCTGG CCCTGAGCGC ACCATTCCCA TCACCCGTGA AGAGAAGCCT 
GCTGTCACCG CAGCCCCCAA GAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001355175.1
CDS	291..617
Translation	MRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK

Target ORF information:

RefSeq Version	NM_001368246.1
Organism	Homo sapiens(human)
Definition	Homo sapiens crystallin alpha B (CRYAB), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001368246.1

ORF Insert Sequence:

ATGCGCCTGG AGAAGGACAG GTTCTCTGTC AACCTGGATG TGAAGCACTT CTCCCCAGAG 
GAACTCAAAG TTAAGGTGTT GGGAGATGTG ATTGAGGTGC ATGGAAAACA TGAAGAGCGC 
CAGGATGAAC ATGGTTTCAT CTCCAGGGAG TTCCACAGGA AATACCGGAT CCCAGCTGAT 
GTAGACCCTC TCACCATTAC TTCATCCCTG TCATCTGATG GGGTCCTCAC TGTGAATGGA 
CCAAGGAAAC AGGTCTCTGG CCCTGAGCGC ACCATTCCCA TCACCCGTGA AGAGAAGCCT 
GCTGTCACCG CAGCCCCCAA GAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	CRYAB
Entrez Gene ID	1410
Full Name	crystallin alpha B
Synonyms	CMD1II,CRYA2,CTPP2,CTRCT16,HEL-S-101,HSPB5,MFM2
General protein information	Preferred Names crystallin alpha B Names alpha-crystallin B chain epididymis secretory protein Li 101 heat shock protein beta-5 heat-shock 20 kD like-protein renal carcinoma antigen NY-REN-27 rosenthal fiber component
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q23.1
Summary	Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].
Disorder MIM:	123590
Disorder Html:	Myopathy, myofibrillar, 2, 608810 (3); Cataract 16, multiple types, 613763 (3); Myopathy, myofibrillar, fatal infantile hypertonic, alpha-B crystallin-related, 613869 (3); Cardiomyopathy, dilated, 1II, 615184 (3)

Homo sapiens (human)	CRYAB	NP_001876.1
	CRYAB	XP_002799808.1
Mus musculus (house mouse)	Cryab	NP_034094.1
Danio rerio (zebrafish)	cryabb	NP_001002670.1
Canis lupus familiaris (dog)	CRYAB	XP_862258.2
Bos taurus (cattle)	CRYAB	NP_776715.1
Gallus gallus (chicken)	CRYAB	NP_990507.1
Pan troglodytes (chimpanzee)	CRYAB	XP_508752.2
Rattus norvegicus (Norway rat)	Cryab	NP_037067.1
Drosophila melanogaster (fruit fly)	l(2)efl	NP_523827.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007162	XP_308606.2
Xenopus tropicalis (tropical clawed frog)	cryab	XP_002932964.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

CRYAB cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

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ORF Insert Sequence:

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