CHD2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CHD2
Entrez Gene ID	1106
Full Name	chromodomain helicase DNA binding protein 2
Synonyms	EEOC
General protein information	Preferred Names chromodomain helicase DNA binding protein 2 Names chromodomain-helicase-DNA-binding protein 2 ATP-dependent helicase CHD2 CHD-2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q26.1
Summary	The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	602119
Disorder Html:	Epileptic encephalopathy, childhood-onset, 615369 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001042572.3	NP_001036037.1	chromodomain-helicase-DNA-binding protein 2 isoform 2
NM_001042572.2	NP_001036037.1	chromodomain-helicase-DNA-binding protein 2 isoform 2
NM_001271.4	NP_001262.3	chromodomain-helicase-DNA-binding protein 2 isoform 1
NM_001271.3	NP_001262.3	chromodomain-helicase-DNA-binding protein 2 isoform 1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	CHD2	XP_413879.3
Danio rerio (zebrafish)	chd2	XP_005159227.1
Oryza sativa (rice)	Os07g0660200	NP_001060530.1
Canis lupus familiaris (dog)	CHD2	XP_005618381.1
Mus musculus (house mouse)	Chd2	NP_001074814.2
Caenorhabditis elegans (roundworm)	chd-1	NP_491994.2
	CHD2	XP_002808499.1
Rattus norvegicus (Norway rat)	Chd2	NP_001100993.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008698	XP_314800.4
Homo sapiens (human)	CHD2	NP_001262.3
Drosophila melanogaster (fruit fly)	Chd1	NP_477197.1
Xenopus tropicalis (tropical clawed frog)	chd2	XP_002933353.1
Pan troglodytes (chimpanzee)	CHD2	XP_001170676.2
Arabidopsis thaliana (thale cress)	CHR5	NP_178970.3

Gene Ontology
Bibliography

Related articles in PubMed

Autism spectrum disorder recurrence, resulting of germline mosaicism for a CHD2 gene missense variant.
Lebrun N, Parent P, Gendras J, Billuart P, Poirier K, Bienvenu T
Clinical genetics92(6)669-670(2017 Dec)

Exome sequencing analysis in a pair of monozygotic twins re-evaluates the genetics behind their intellectual disability and reveals a CHD2 mutation.
Pinto AM, Bianciardi L, Mencarelli MA, Imperatore V, Di Marco C, Furini S, Suppiej A, Salviati L, Tenconi R, Ariani F, Mari F, Renieri A
Brain & development38(6)590-6(2016 Jun)

PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining.
Luijsterburg MS, de Krijger I, Wiegant WW, Shah RG, Smeenk G, de Groot AJL, Pines A, Vertegaal ACO, Jacobs JJL, Shah GM, van Attikum H
Molecular cell61(4)547-562(2016 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

study reports monozygotic twins with a global neurodevelopmental delay associated with an autism spectrum disorder, hypotonia, postnatal microcephaly, stereotypic movements and circadian rhythm alterations in association with late-onset epilepsy; identified a CHD2 mutation, previously described in association with a phenotypic spectrum overlapping our patients' phenotype
Title: Exome sequencing analysis in a pair of monozygotic twins re-evaluates the genetics behind their intellectual disability and reveals a CHD2 mutation.

Results indicate a PARP1-dependent mechanism that regulates non-homologous end-joining through localized chromatin expansion and deposition of the histone variant H3.3 by CHD2 at DNA breaks promoting DNA repair.
Title: PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining.

CHD2 mutations are responsible in rare cases for generalized epilepsy with myoclonic-atonic seizures.
Title: CHD2 mutations are a rare cause of generalized epilepsy with myoclonic-atonic seizures.

CHD2 is a cancer driver and has a role as chromatin remodeler in chronic lymphocytic leukemia.
Title: Mutations in CHD2 cause defective association with active chromatin in chronic lymphocytic leukemia.

CHD2 mutation is the first identified cause of the archetypal generalized photosensitive epilepsy syndrome
Title: CHD2 variants are a risk factor for photosensitivity in epilepsy.

The following CHD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CHD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25946	NM_001042572.3 Latest version!	Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$293.30 $419.00
OHu25723	NM_001271.4 Latest version!	Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$923.30 $1319.00
View Old Accession Versions >>
OHu25946	NM_001042572.2	Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$293.30 $419.00
OHu25723	NM_001271.3	Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$923.30 $1319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CHD2 ( NM_001042572.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001036037.1 Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu25946
Clone ID Related Accession (Same CDS sequence)	NM_001042572.3 , NM_001042572.2
Accession Version	NM_001042572.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1506bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	chromodomain-helicase-DNA-binding protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN277753.1, BC007347.2 and BU630151.1. This sequence is a reference standard in the RefSeqGene project. On Jun 18, 2019 this sequence version replaced NM_001042572.2. Transcript Variant: This variant (2) lacks multiple 3' exons and has an alternate 3' end, as compared to variant 1. The encoded isoform (2) has a much shorter and distinct C-terminus, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.107308.1, SRR1660807.230769.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGAGAA ATAAGGACAA AAGCCAAGAG GAGGACAGTT CGCTACACAG CAATGCATCG 
AGTCACTCAG CCTCTGAAGA AGCTTCGGGT TCAGACTCAG GCAGTCAGTC GGAAAGTGAG 
CAGGGAAGTG ATCCAGGAAG TGGACATGGC AGCGAGTCGA ACAGCAGCTC TGAATCTTCT 
GAGAGTCAGT CGGAATCTGA GAGCGAATCA GCAGGTTCCA AATCCCAGCC AGTCCTCCCA 
GAAGCCAAAG AGAAGCCAGC CTCTAAGAAG GAACGGATAG CTGATGTGAA GAAGATGTGG 
GAAGAATATC CTGATGTTTA TGGGGTCAGG CGGTCAAACC GAAGCAGACA AGAACCATCG 
CGATTTAATA TTAAGGAAGA GGCAAGTAGC GGGTCTGAGA GTGGGAGCCC AAAAAGAAGA 
GGCCAGAGGC AGCTGAAAAA ACAAGAAAAA TGGAAACAGG AACCCTCAGA AGATGAACAG 
GAACAAGGCA CCAGTGCAGA GAGTGAGCCA GAACAAAAAA AAGTAAAAGC CAGAAGACCT 
GTCCCCAGAA GAACAGTGCC CAAACCTCGT GTTAAAAAGC AGCCGAAGAC TCAGCGTGGA 
AAGAGAAAAA AGCAAGATTC TTCTGATGAG GATGATGATG ATGACGAAGC TCCCAAAAGG 
CAGACTCGTC GAAGAGCGGC TAAAAACGTT AGTTACAAAG AAGATGATGA CTTTGAGACT 
GACTCAGATG ATCTCATTGA AATGACTGGA GAAGGAGTTG ATGAACAGCA AGATAATAGT 
GAAACTATTG AAAAGGTCTT AGATTCAAGA CTGGGAAAGA AAGGAGCCAC TGGAGCATCT 
ACTACTGTAT ATGCGATTGA AGCTAATGGC GACCCTAGTG GTGACTTTGA CACTGAAAAG 
GATGAAGGTG AAATCCAGTA CCTCATCAAG TGGAAGGGTT GGTCTTACAT CCACAGCACA 
TGGGAGAGTG AAGAATCCTT ACAGCAACAG AAAGTGAAGG GCCTAAAAAA ACTAGAGAAC 
TTCAAGAAAA AAGAGGACGA AATCAAACAA TGGTTAGGGA AAGTTTCTCC TGAAGATGTA 
GAATATTTCA ATTGCCAACA GGAGCTGGCT TCAGAGTTGA ATAAACAGTA TCAGATAGTA 
GAAAGAGTAA TAGCTGTGAA GACAAGTAAA TCTACATTGG GTCAAACAGA TTTTCCAGCT 
CATAGTCGGA AGCCGGCACC CTCAAATGAG CCCGAATATC TATGTAAATG GATGGGACTC 
CCCTATTCAG AGTGTAGCTG GGAAGATGAA GCCCTCATTG GAAAGAAATT CCAGAATTGC 
ATTGACAGCT TCCACAGTAG GAACAACTCA AAAACCATCC CAACAAGAGA ATGCAAGGCC 
CTGAAGCAGA GACCACGATT TGTAGCTTTA AAGAAACAAC CTGCATATTT AGGAGGGGAG 
AATCTGGAAC TTCGAGATTA TCAGCTAGAA GGTCTAAACT GGCTAGCTCA TTCCTGGTGC 
AAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001036037.1
CDS	573..2078
Translation	MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCK

Target ORF information:

RefSeq Version	NM_001042572.3
Organism	Homo sapiens(human)
Definition	Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042572.3

ORF Insert Sequence:

ATGATGAGAA ATAAGGACAA AAGCCAAGAG GAGGACAGTT CGCTACACAG CAATGCATCG 
AGTCACTCAG CCTCTGAAGA AGCTTCGGGT TCAGACTCAG GCAGTCAGTC GGAAAGTGAG 
CAGGGAAGTG ATCCAGGAAG TGGACATGGC AGCGAGTCGA ACAGCAGCTC TGAATCTTCT 
GAGAGTCAGT CGGAATCTGA GAGCGAATCA GCAGGTTCCA AATCCCAGCC AGTCCTCCCA 
GAAGCCAAAG AGAAGCCAGC CTCTAAGAAG GAACGGATAG CTGATGTGAA GAAGATGTGG 
GAAGAATATC CTGATGTTTA TGGGGTCAGG CGGTCAAACC GAAGCAGACA AGAACCATCG 
CGATTTAATA TTAAGGAAGA GGCAAGTAGC GGGTCTGAGA GTGGGAGCCC AAAAAGAAGA 
GGCCAGAGGC AGCTGAAAAA ACAAGAAAAA TGGAAACAGG AACCCTCAGA AGATGAACAG 
GAACAAGGCA CCAGTGCAGA GAGTGAGCCA GAACAAAAAA AAGTAAAAGC CAGAAGACCT 
GTCCCCAGAA GAACAGTGCC CAAACCTCGT GTTAAAAAGC AGCCGAAGAC TCAGCGTGGA 
AAGAGAAAAA AGCAAGATTC TTCTGATGAG GATGATGATG ATGACGAAGC TCCCAAAAGG 
CAGACTCGTC GAAGAGCGGC TAAAAACGTT AGTTACAAAG AAGATGATGA CTTTGAGACT 
GACTCAGATG ATCTCATTGA AATGACTGGA GAAGGAGTTG ATGAACAGCA AGATAATAGT 
GAAACTATTG AAAAGGTCTT AGATTCAAGA CTGGGAAAGA AAGGAGCCAC TGGAGCATCT 
ACTACTGTAT ATGCGATTGA AGCTAATGGC GACCCTAGTG GTGACTTTGA CACTGAAAAG 
GATGAAGGTG AAATCCAGTA CCTCATCAAG TGGAAGGGTT GGTCTTACAT CCACAGCACA 
TGGGAGAGTG AAGAATCCTT ACAGCAACAG AAAGTGAAGG GCCTAAAAAA ACTAGAGAAC 
TTCAAGAAAA AAGAGGACGA AATCAAACAA TGGTTAGGGA AAGTTTCTCC TGAAGATGTA 
GAATATTTCA ATTGCCAACA GGAGCTGGCT TCAGAGTTGA ATAAACAGTA TCAGATAGTA 
GAAAGAGTAA TAGCTGTGAA GACAAGTAAA TCTACATTGG GTCAAACAGA TTTTCCAGCT 
CATAGTCGGA AGCCGGCACC CTCAAATGAG CCCGAATATC TATGTAAATG GATGGGACTC 
CCCTATTCAG AGTGTAGCTG GGAAGATGAA GCCCTCATTG GAAAGAAATT CCAGAATTGC 
ATTGACAGCT TCCACAGTAG GAACAACTCA AAAACCATCC CAACAAGAGA ATGCAAGGCC 
CTGAAGCAGA GACCACGATT TGTAGCTTTA AAGAAACAAC CTGCATATTT AGGAGGGGAG 
AATCTGGAAC TTCGAGATTA TCAGCTAGAA GGTCTAAACT GGCTAGCTCA TTCCTGGTGC 
AAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHD2 ( NM_001042572.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001036037.1 Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu25946
Clone ID Related Accession (Same CDS sequence)	NM_001042572.3 , NM_001042572.2
Accession Version	NM_001042572.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1506bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	chromodomain-helicase-DNA-binding protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN277753.1, BC007347.2 and BU630151.1. On Nov 28, 2006 this sequence version replaced NM_001042572.1. Transcript Variant: This variant (2) lacks multiple 3' exons and has an alternate 3' end, as compared to variant 1. The encoded isoform (2) has a much shorter and distinct C-terminus, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.89249.1, BC007347.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGAGAA ATAAGGACAA AAGCCAAGAG GAGGACAGTT CGCTACACAG CAATGCATCG 
AGTCACTCAG CCTCTGAAGA AGCTTCGGGT TCAGACTCAG GCAGTCAGTC GGAAAGTGAG 
CAGGGAAGTG ATCCAGGAAG TGGACATGGC AGCGAGTCGA ACAGCAGCTC TGAATCTTCT 
GAGAGTCAGT CGGAATCTGA GAGCGAATCA GCAGGTTCCA AATCCCAGCC AGTCCTCCCA 
GAAGCCAAAG AGAAGCCAGC CTCTAAGAAG GAACGGATAG CTGATGTGAA GAAGATGTGG 
GAAGAATATC CTGATGTTTA TGGGGTCAGG CGGTCAAACC GAAGCAGACA AGAACCATCG 
CGATTTAATA TTAAGGAAGA GGCAAGTAGC GGGTCTGAGA GTGGGAGCCC AAAAAGAAGA 
GGCCAGAGGC AGCTGAAAAA ACAAGAAAAA TGGAAACAGG AACCCTCAGA AGATGAACAG 
GAACAAGGCA CCAGTGCAGA GAGTGAGCCA GAACAAAAAA AAGTAAAAGC CAGAAGACCT 
GTCCCCAGAA GAACAGTGCC CAAACCTCGT GTTAAAAAGC AGCCGAAGAC TCAGCGTGGA 
AAGAGAAAAA AGCAAGATTC TTCTGATGAG GATGATGATG ATGACGAAGC TCCCAAAAGG 
CAGACTCGTC GAAGAGCGGC TAAAAACGTT AGTTACAAAG AAGATGATGA CTTTGAGACT 
GACTCAGATG ATCTCATTGA AATGACTGGA GAAGGAGTTG ATGAACAGCA AGATAATAGT 
GAAACTATTG AAAAGGTCTT AGATTCAAGA CTGGGAAAGA AAGGAGCCAC TGGAGCATCT 
ACTACTGTAT ATGCGATTGA AGCTAATGGC GACCCTAGTG GTGACTTTGA CACTGAAAAG 
GATGAAGGTG AAATCCAGTA CCTCATCAAG TGGAAGGGTT GGTCTTACAT CCACAGCACA 
TGGGAGAGTG AAGAATCCTT ACAGCAACAG AAAGTGAAGG GCCTAAAAAA ACTAGAGAAC 
TTCAAGAAAA AAGAGGACGA AATCAAACAA TGGTTAGGGA AAGTTTCTCC TGAAGATGTA 
GAATATTTCA ATTGCCAACA GGAGCTGGCT TCAGAGTTGA ATAAACAGTA TCAGATAGTA 
GAAAGAGTAA TAGCTGTGAA GACAAGTAAA TCTACATTGG GTCAAACAGA TTTTCCAGCT 
CATAGTCGGA AGCCGGCACC CTCAAATGAG CCCGAATATC TATGTAAATG GATGGGACTC 
CCCTATTCAG AGTGTAGCTG GGAAGATGAA GCCCTCATTG GAAAGAAATT CCAGAATTGC 
ATTGACAGCT TCCACAGTAG GAACAACTCA AAAACCATCC CAACAAGAGA ATGCAAGGCC 
CTGAAGCAGA GACCACGATT TGTAGCTTTA AAGAAACAAC CTGCATATTT AGGAGGGGAG 
AATCTGGAAC TTCGAGATTA TCAGCTAGAA GGTCTAAACT GGCTAGCTCA TTCCTGGTGC 
AAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001036037.1
CDS	576..2081
Translation	MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCK

Target ORF information:

RefSeq Version	NM_001042572.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042572.2

ORF Insert Sequence:

ATGATGAGAA ATAAGGACAA AAGCCAAGAG GAGGACAGTT CGCTACACAG CAATGCATCG 
AGTCACTCAG CCTCTGAAGA AGCTTCGGGT TCAGACTCAG GCAGTCAGTC GGAAAGTGAG 
CAGGGAAGTG ATCCAGGAAG TGGACATGGC AGCGAGTCGA ACAGCAGCTC TGAATCTTCT 
GAGAGTCAGT CGGAATCTGA GAGCGAATCA GCAGGTTCCA AATCCCAGCC AGTCCTCCCA 
GAAGCCAAAG AGAAGCCAGC CTCTAAGAAG GAACGGATAG CTGATGTGAA GAAGATGTGG 
GAAGAATATC CTGATGTTTA TGGGGTCAGG CGGTCAAACC GAAGCAGACA AGAACCATCG 
CGATTTAATA TTAAGGAAGA GGCAAGTAGC GGGTCTGAGA GTGGGAGCCC AAAAAGAAGA 
GGCCAGAGGC AGCTGAAAAA ACAAGAAAAA TGGAAACAGG AACCCTCAGA AGATGAACAG 
GAACAAGGCA CCAGTGCAGA GAGTGAGCCA GAACAAAAAA AAGTAAAAGC CAGAAGACCT 
GTCCCCAGAA GAACAGTGCC CAAACCTCGT GTTAAAAAGC AGCCGAAGAC TCAGCGTGGA 
AAGAGAAAAA AGCAAGATTC TTCTGATGAG GATGATGATG ATGACGAAGC TCCCAAAAGG 
CAGACTCGTC GAAGAGCGGC TAAAAACGTT AGTTACAAAG AAGATGATGA CTTTGAGACT 
GACTCAGATG ATCTCATTGA AATGACTGGA GAAGGAGTTG ATGAACAGCA AGATAATAGT 
GAAACTATTG AAAAGGTCTT AGATTCAAGA CTGGGAAAGA AAGGAGCCAC TGGAGCATCT 
ACTACTGTAT ATGCGATTGA AGCTAATGGC GACCCTAGTG GTGACTTTGA CACTGAAAAG 
GATGAAGGTG AAATCCAGTA CCTCATCAAG TGGAAGGGTT GGTCTTACAT CCACAGCACA 
TGGGAGAGTG AAGAATCCTT ACAGCAACAG AAAGTGAAGG GCCTAAAAAA ACTAGAGAAC 
TTCAAGAAAA AAGAGGACGA AATCAAACAA TGGTTAGGGA AAGTTTCTCC TGAAGATGTA 
GAATATTTCA ATTGCCAACA GGAGCTGGCT TCAGAGTTGA ATAAACAGTA TCAGATAGTA 
GAAAGAGTAA TAGCTGTGAA GACAAGTAAA TCTACATTGG GTCAAACAGA TTTTCCAGCT 
CATAGTCGGA AGCCGGCACC CTCAAATGAG CCCGAATATC TATGTAAATG GATGGGACTC 
CCCTATTCAG AGTGTAGCTG GGAAGATGAA GCCCTCATTG GAAAGAAATT CCAGAATTGC 
ATTGACAGCT TCCACAGTAG GAACAACTCA AAAACCATCC CAACAAGAGA ATGCAAGGCC 
CTGAAGCAGA GACCACGATT TGTAGCTTTA AAGAAACAAC CTGCATATTT AGGAGGGGAG 
AATCTGGAAC TTCGAGATTA TCAGCTAGAA GGTCTAAACT GGCTAGCTCA TTCCTGGTGC 
AAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHD2 ( NM_001271.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001262.3 Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25723
Clone ID Related Accession (Same CDS sequence)	NM_001271.4 , NM_001271.3
Accession Version	NM_001271.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5487bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-01
Organism	Homo sapiens(human)
Product	chromodomain-helicase-DNA-binding protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF006514.1, DB121252.1, AC013394.12, DB111282.1, CT003638.1 and AA907775.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_001271.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000394196.9/ ENSP00000377747.4 RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATGAGAA ATAAGGACAA AAGCCAAGAG GAGGACAGTT CGCTACACAG CAATGCATCG 
AGTCACTCAG CCTCTGAAGA AGCTTCGGGT TCAGACTCAG GCAGTCAGTC GGAAAGTGAG 
CAGGGAAGTG ATCCAGGAAG TGGACATGGC AGCGAGTCGA ACAGCAGCTC TGAATCTTCT 
GAGAGTCAGT CGGAATCTGA GAGCGAATCA GCAGGTTCCA AATCCCAGCC AGTCCTCCCA 
GAAGCCAAAG AGAAGCCAGC CTCTAAGAAG GAACGGATAG CTGATGTGAA GAAGATGTGG 
GAAGAATATC CTGATGTTTA TGGGGTCAGG CGGTCAAACC GAAGCAGACA AGAACCATCG 
CGATTTAATA TTAAGGAAGA GGCAAGTAGC GGGTCTGAGA GTGGGAGCCC AAAAAGAAGA 
GGCCAGAGGC AGCTGAAAAA ACAAGAAAAA TGGAAACAGG AACCCTCAGA AGATGAACAG 
GAACAAGGCA CCAGTGCAGA GAGTGAGCCA GAACAAAAAA AAGTAAAAGC CAGAAGACCT 
GTCCCCAGAA GAACAGTGCC CAAACCTCGT GTTAAAAAGC AGCCGAAGAC TCAGCGTGGA 
AAGAGAAAAA AGCAAGATTC TTCTGATGAG GATGATGATG ATGACGAAGC TCCCAAAAGG 
CAGACTCGTC GAAGAGCGGC TAAAAACGTT AGTTACAAAG AAGATGATGA CTTTGAGACT 
GACTCAGATG ATCTCATTGA AATGACTGGA GAAGGAGTTG ATGAACAGCA AGATAATAGT 
GAAACTATTG AAAAGGTCTT AGATTCAAGA CTGGGAAAGA AAGGAGCCAC TGGAGCATCT 
ACTACTGTAT ATGCGATTGA AGCTAATGGC GACCCTAGTG GTGACTTTGA CACTGAAAAG 
GATGAAGGTG AAATCCAGTA CCTCATCAAG TGGAAGGGTT GGTCTTACAT CCACAGCACA 
TGGGAGAGTG AAGAATCCTT ACAGCAACAG AAAGTGAAGG GCCTAAAAAA ACTAGAGAAC 
TTCAAGAAAA AAGAGGACGA AATCAAACAA TGGTTAGGGA AAGTTTCTCC TGAAGATGTA 
GAATATTTCA ATTGCCAACA GGAGCTGGCT TCAGAGTTGA ATAAACAGTA TCAGATAGTA 
GAAAGAGTAA TAGCTGTGAA GACAAGTAAA TCTACATTGG GTCAAACAGA TTTTCCAGCT 
CATAGTCGGA AGCCGGCACC CTCAAATGAG CCCGAATATC TATGTAAATG GATGGGACTC 
CCCTATTCAG AGTGTAGCTG GGAAGATGAA GCCCTCATTG GAAAGAAATT CCAGAATTGC 
ATTGACAGCT TCCACAGTAG GAACAACTCA AAAACCATCC CAACAAGAGA ATGCAAGGCC 
CTGAAGCAGA GACCACGATT TGTAGCTTTA AAGAAACAAC CTGCATATTT AGGAGGGGAG 
AATCTGGAAC TTCGAGATTA TCAGCTAGAA GGTCTAAACT GGCTAGCTCA TTCCTGGTGC 
AAAAATAATA GTGTAATCCT TGCTGATGAA ATGGGCCTAG GAAAGACCAT CCAGACCATA 
TCATTCCTCT CCTACCTGTT CCACCAACAC CAGCTGTATG GCCCCTTTCT TATAGTCGTC 
CCTTTATCCA CCCTCACCTC ATGGCAGAGA GAGTTTGAAA TCTGGGCACC AGAGATTAAC 
GTAGTGGTTT ACATAGGTGA CCTGATGAGC AGAAATACGA TACGGGAATA TGAATGGATT 
CATTCCCAAA CCAAAAGATT GAAGTTCAAC GCACTTATAA CAACATATGA GATCCTCTTG 
AAAGATAAGA CTGTGCTGGG CAGTATTAAC TGGGCCTTTC TGGGAGTGGA TGAAGCCCAT 
CGGTTGAAGA ATGATGACTC TTTATTGTAT AAAACTCTGA TTGATTTCAA GTCCAACCAT 
AGGCTCCTGA TTACGGGGAC CCCTCTTCAG AATTCCCTCA AAGAGCTCTG GTCCTTGCTG 
CACTTTATTA TGCCGGAGAA GTTTGAATTT TGGGAAGATT TTGAAGAAGA CCATGGGAAG 
GGGAGAGAAA ATGGCTACCA GAGTCTTCAT AAGGTGCTAG AGCCTTTCCT TCTCCGGAGA 
GTCAAAAAAG ATGTGGAGAA ATCCCTTCCT GCTAAAGTGG AACAGATTCT CAGGGTGGAG 
ATGTCAGCCC TTCAGAAACA GTATTACAAG TGGATTCTGA CCAGGAATTA CAAGGCTCTT 
GCCAAAGGAA CAAGAGGCAG CACATCTGGT TTTCTTAATA TTGTGATGGA ACTGAAAAAA 
TGTTGCAACC ACTGCTATCT GATTAAACCC CCTGAAGAAA ATGAAAGGGA AAATGGACAG 
GAGATTCTTC TGTCCCTCAT AAGGAGCAGT GGGAAGTTGA TTTTATTAGA CAAACTGTTG 
ACAAGACTTC GAGAAAGGGG GAATCGAGTG CTTATCTTCT CTCAGATGGT GAGAATGTTG 
GATATCCTGG CTGAATACCT AACTATTAAA CACTATCCTT TCCAGCGTCT GGATGGTTCC 
ATCAAGGGAG AAATCCGAAA ACAGGCACTG GACCACTTCA ATGCAGATGG GTCTGAGGAC 
TTCTGTTTCC TGCTCTCGAC AAGGGCTGGT GGCCTGGGAA TCAATTTGGC TTCAGCGGAC 
ACAGTCGTCA TCTTTGACTC TGACTGGAAC CCCCAGAATG ACTTGCAGGC ACAAGCCCGA 
GCGCATAGAA TTGGTCAAAA GAAGCAGGTA AATATTTACC GCTTAGTTAC AAAGGGGACT 
GTGGAGGAGG AGATCATAGA ACGGGCCAAA AAGAAGATGG TATTAGATCA TCTGGTGATT 
CAGCGCATGG ACACCACTGG CCGGACGATC CTGGAAAACA ACTCAGGAAG GTCCAACTCA 
AATCCTTTTA ATAAAGAAGA GCTGACAGCT ATTTTGAAAT TTGGAGCAGA GGATCTCTTC 
AAAGAACTGG AAGGGGAGGA ATCAGAACCT CAGGAAATGG ATATAGATGA AATTTTGCGG 
TTGGCTGAAA CGAGAGAGAA TGAAGTGTCA ACAAGTGCAA CAGATGAACT TCTATCACAG 
TTTAAGGTTG CCAACTTTGC AACAATGGAA GATGAAGAAG AGCTAGAAGA GCGTCCTCAC 
AAGGACTGGG ATGAGATCAT TCCAGAGGAA CAAAGGAAAA AAGTAGAGGA GGAAGAGCGG 
CAGAAGGAGC TAGAAGAAAT TTATATGCTG CCTCGAATTC GGAGTTCCAC TAAAAAGGCT 
CAGACAAATG ACAGTGACTC TGACACTGAG TCTAAGAGGC AGGCCCAGAG ATCCTCTGCT 
TCTGAGAGTG AAACGGAAGA CTCTGATGAT GACAAGAAGC CAAAGCGCAG AGGGCGTCCG 
AGGAGTGTGC GGAAGGACCT CGTGGAGGGA TTTACTGATG CAGAGATCCG AAGGTTCATC 
AAGGCTTATA AGAAGTTTGG TCTCCCTCTT GAACGGCTGG AGTGCATAGC ACGTGATGCT 
GAGCTGGTAG ATAAGTCGGT GGCAGATCTG AAGCGCCTGG GTGAACTGAT CCACAACAGC 
TGTGTGTCAG CAATGCAGGA ATACGAAGAG CAGCTGAAAG AAAATGCCAG CGAGGGAAAA 
GGACCAGGGA AAAGGAGAGG TCCAACAATC AAGATATCCG GAGTTCAGGT TAATGTGAAA 
TCCATTATCC AACATGAAGA GGAGTTTGAG ATGCTGCATA AATCTATCCC TGTGGACCCT 
GAAGAAAAAA AAAAATACTG CTTAACCTGT CGTGTCAAAG CTGCACATTT TGATGTAGAG 
TGGGGGGTGG AAGATGATTC TCGCCTGTTG CTGGGGATTT ATGAACATGG CTATGGAAAC 
TGGGAGTTAA TTAAAACAGA CCCAGAGCTT AAATTAACTG ACAAAATTCT GCCGGTGGAG 
ACAGATAAAA AGCCTCAGGG GAAGCAGCTA CAGACCCGAG CGGATTACTT GTTGAAGCTG 
CTCAGAAAGG GTCTGGAGAA GAAGGGGGCT GTGACAGGTG GGGAAGAGGC CAAATTAAAG 
AAGCGGAAGC CTCGGGTAAA GAAGGAAAAC AAAGTGCCCA GGCTGAAAGA GGAGCATGGA 
ATTGAGCTTT CATCTCCTAG GCATTCAGAT AATCCATCAG AAGAGGGAGA AGTGAAAGAT 
GATGGCTTGG AAAAAAGTCC AATGAAAAAA AAACAGAAGA AGAAAGAGAA CAAGGAGAAC 
AAGGAGAAAC AAATGAGTTC TAGGAAAGAC AAAGAAGGGG ACAAGGAAAG AAAGAAGTCA 
AAAGATAAGA AAGAGAAGCC TAAAAGTGGT GATGCCAAAT CTTCGAGTAA ATCAAAGCGA 
TCTCAGGGTC CTGTCCATAT TACAGCAGGA AGTGAACCTG TCCCCATTGG AGAGGATGAG 
GATGATGATC TGGACCAGGA GACATTCAGC ATATGTAAGG AGAGGATGAG GCCCGTGAAA 
AAGGCACTGA AACAGCTCGA CAAACCTGAC AAGGGGCTCA ACGTGCAAGA ACAGCTGGAA 
CACACCCGGA ACTGCCTGCT GAAAATCGGA GACCGGATAG CCGAGTGCCT TAAAGCCTAC 
TCAGATCAGG AGCACATCAA ACTCTGGAGG AGGAACCTAT GGATTTTTGT TTCCAAGTTT 
ACAGAATTTG ATGCTCGAAA ACTGCATAAG TTATACAAGA TGGCTCATAA GAAAAGGTCT 
CAAGAAGAAG AGGAGCAAAA GAAGAAAGAC GACGTGACTG GGGGTAAGAA ACCATTTCGT 
CCAGAGGCCT CAGGCTCCAG CCGGGACTCT CTGATATCTC AGTCCCATAC CTCACACAAC 
CTTCACCCTC AGAAGCCTCA TTTGCCTGCC TCCCATGGCC CACAGATGCA TGGACACCCA 
AGAGATAACT ACAATCACCC CAACAAGAGA CACTTCAGTA ATGCAGATCG AGGAGACTGG 
CAGAGGGAAA GAAAGTTCAA CTATGGTGGT GGCAACAACA ATCCACCATG GGGAAGCGAC 
AGGCACCATC AGTATGAGCA GCACTGGTAC AAGGACCACC ATTATGGGGA CCGGCGACAT 
ATGGATGCCC ACCGTTCCGG AAGCTATCGA CCCAACAACA TGTCCAGAAA GAGGCCTTAT 
GACCAGTACA GCAGTGACCG AGACCACCGG GGACACAGAG ATTATTATGA CAGGCACCAT 
CATGACTCCA AGCGGAGGAG ATCCGATGAA TTTAGGCCTC AAAATTACCA CCAGCAGGAT 
TTCCGACGAA TGTCTGATCA CCGCCCCGCT ATGGGCTACC ATGGCCAGGG ACCCTCAGAC 
CATTACCGCT CTTTCCACAC AGATAAACTG GGGGAATATA AACAGCCTCT ACCCCCATTG 
CACCCTGCAG TCTCAGATCC TCGCTCACCC CCTTCTCAGA AATCTCCTCA CGATTCCAAG 
TCACCCCTGG ATCATAGGTC TCCTTTGGAG AGATCACTAG AACAGAAAAA CAACCCAGAT 
TATAACTGGA ATGTTCGGAA AACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001262.3
CDS	573..6059
Translation	MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIKPPEENERENGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDVTGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKPHLPASHGPQMHGHPRDNYNHPNKRHFSNADRGDWQRERKFNYGGGNNNPPWGSDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYDQYSSDRDHRGHRDYYDRHHHDSKRRRSDEFRPQNYHQQDFRRMSDHRPAMGYHGQGPSDHYRSFHTDKLGEYKQPLPPLHPAVSDPRSPPSQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT

Target ORF information:

RefSeq Version	NM_001271.4
Organism	Homo sapiens(human)
Definition	Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271.4

ORF Insert Sequence:

ATGATGAGAA ATAAGGACAA AAGCCAAGAG GAGGACAGTT CGCTACACAG CAATGCATCG 
AGTCACTCAG CCTCTGAAGA AGCTTCGGGT TCAGACTCAG GCAGTCAGTC GGAAAGTGAG 
CAGGGAAGTG ATCCAGGAAG TGGACATGGC AGCGAGTCGA ACAGCAGCTC TGAATCTTCT 
GAGAGTCAGT CGGAATCTGA GAGCGAATCA GCAGGTTCCA AATCCCAGCC AGTCCTCCCA 
GAAGCCAAAG AGAAGCCAGC CTCTAAGAAG GAACGGATAG CTGATGTGAA GAAGATGTGG 
GAAGAATATC CTGATGTTTA TGGGGTCAGG CGGTCAAACC GAAGCAGACA AGAACCATCG 
CGATTTAATA TTAAGGAAGA GGCAAGTAGC GGGTCTGAGA GTGGGAGCCC AAAAAGAAGA 
GGCCAGAGGC AGCTGAAAAA ACAAGAAAAA TGGAAACAGG AACCCTCAGA AGATGAACAG 
GAACAAGGCA CCAGTGCAGA GAGTGAGCCA GAACAAAAAA AAGTAAAAGC CAGAAGACCT 
GTCCCCAGAA GAACAGTGCC CAAACCTCGT GTTAAAAAGC AGCCGAAGAC TCAGCGTGGA 
AAGAGAAAAA AGCAAGATTC TTCTGATGAG GATGATGATG ATGACGAAGC TCCCAAAAGG 
CAGACTCGTC GAAGAGCGGC TAAAAACGTT AGTTACAAAG AAGATGATGA CTTTGAGACT 
GACTCAGATG ATCTCATTGA AATGACTGGA GAAGGAGTTG ATGAACAGCA AGATAATAGT 
GAAACTATTG AAAAGGTCTT AGATTCAAGA CTGGGAAAGA AAGGAGCCAC TGGAGCATCT 
ACTACTGTAT ATGCGATTGA AGCTAATGGC GACCCTAGTG GTGACTTTGA CACTGAAAAG 
GATGAAGGTG AAATCCAGTA CCTCATCAAG TGGAAGGGTT GGTCTTACAT CCACAGCACA 
TGGGAGAGTG AAGAATCCTT ACAGCAACAG AAAGTGAAGG GCCTAAAAAA ACTAGAGAAC 
TTCAAGAAAA AAGAGGACGA AATCAAACAA TGGTTAGGGA AAGTTTCTCC TGAAGATGTA 
GAATATTTCA ATTGCCAACA GGAGCTGGCT TCAGAGTTGA ATAAACAGTA TCAGATAGTA 
GAAAGAGTAA TAGCTGTGAA GACAAGTAAA TCTACATTGG GTCAAACAGA TTTTCCAGCT 
CATAGTCGGA AGCCGGCACC CTCAAATGAG CCCGAATATC TATGTAAATG GATGGGACTC 
CCCTATTCAG AGTGTAGCTG GGAAGATGAA GCCCTCATTG GAAAGAAATT CCAGAATTGC 
ATTGACAGCT TCCACAGTAG GAACAACTCA AAAACCATCC CAACAAGAGA ATGCAAGGCC 
CTGAAGCAGA GACCACGATT TGTAGCTTTA AAGAAACAAC CTGCATATTT AGGAGGGGAG 
AATCTGGAAC TTCGAGATTA TCAGCTAGAA GGTCTAAACT GGCTAGCTCA TTCCTGGTGC 
AAAAATAATA GTGTAATCCT TGCTGATGAA ATGGGCCTAG GAAAGACCAT CCAGACCATA 
TCATTCCTCT CCTACCTGTT CCACCAACAC CAGCTGTATG GCCCCTTTCT TATAGTCGTC 
CCTTTATCCA CCCTCACCTC ATGGCAGAGA GAGTTTGAAA TCTGGGCACC AGAGATTAAC 
GTAGTGGTTT ACATAGGTGA CCTGATGAGC AGAAATACGA TACGGGAATA TGAATGGATT 
CATTCCCAAA CCAAAAGATT GAAGTTCAAC GCACTTATAA CAACATATGA GATCCTCTTG 
AAAGATAAGA CTGTGCTGGG CAGTATTAAC TGGGCCTTTC TGGGAGTGGA TGAAGCCCAT 
CGGTTGAAGA ATGATGACTC TTTATTGTAT AAAACTCTGA TTGATTTCAA GTCCAACCAT 
AGGCTCCTGA TTACGGGGAC CCCTCTTCAG AATTCCCTCA AAGAGCTCTG GTCCTTGCTG 
CACTTTATTA TGCCGGAGAA GTTTGAATTT TGGGAAGATT TTGAAGAAGA CCATGGGAAG 
GGGAGAGAAA ATGGCTACCA GAGTCTTCAT AAGGTGCTAG AGCCTTTCCT TCTCCGGAGA 
GTCAAAAAAG ATGTGGAGAA ATCCCTTCCT GCTAAAGTGG AACAGATTCT CAGGGTGGAG 
ATGTCAGCCC TTCAGAAACA GTATTACAAG TGGATTCTGA CCAGGAATTA CAAGGCTCTT 
GCCAAAGGAA CAAGAGGCAG CACATCTGGT TTTCTTAATA TTGTGATGGA ACTGAAAAAA 
TGTTGCAACC ACTGCTATCT GATTAAACCC CCTGAAGAAA ATGAAAGGGA AAATGGACAG 
GAGATTCTTC TGTCCCTCAT AAGGAGCAGT GGGAAGTTGA TTTTATTAGA CAAACTGTTG 
ACAAGACTTC GAGAAAGGGG GAATCGAGTG CTTATCTTCT CTCAGATGGT GAGAATGTTG 
GATATCCTGG CTGAATACCT AACTATTAAA CACTATCCTT TCCAGCGTCT GGATGGTTCC 
ATCAAGGGAG AAATCCGAAA ACAGGCACTG GACCACTTCA ATGCAGATGG GTCTGAGGAC 
TTCTGTTTCC TGCTCTCGAC AAGGGCTGGT GGCCTGGGAA TCAATTTGGC TTCAGCGGAC 
ACAGTCGTCA TCTTTGACTC TGACTGGAAC CCCCAGAATG ACTTGCAGGC ACAAGCCCGA 
GCGCATAGAA TTGGTCAAAA GAAGCAGGTA AATATTTACC GCTTAGTTAC AAAGGGGACT 
GTGGAGGAGG AGATCATAGA ACGGGCCAAA AAGAAGATGG TATTAGATCA TCTGGTGATT 
CAGCGCATGG ACACCACTGG CCGGACGATC CTGGAAAACA ACTCAGGAAG GTCCAACTCA 
AATCCTTTTA ATAAAGAAGA GCTGACAGCT ATTTTGAAAT TTGGAGCAGA GGATCTCTTC 
AAAGAACTGG AAGGGGAGGA ATCAGAACCT CAGGAAATGG ATATAGATGA AATTTTGCGG 
TTGGCTGAAA CGAGAGAGAA TGAAGTGTCA ACAAGTGCAA CAGATGAACT TCTATCACAG 
TTTAAGGTTG CCAACTTTGC AACAATGGAA GATGAAGAAG AGCTAGAAGA GCGTCCTCAC 
AAGGACTGGG ATGAGATCAT TCCAGAGGAA CAAAGGAAAA AAGTAGAGGA GGAAGAGCGG 
CAGAAGGAGC TAGAAGAAAT TTATATGCTG CCTCGAATTC GGAGTTCCAC TAAAAAGGCT 
CAGACAAATG ACAGTGACTC TGACACTGAG TCTAAGAGGC AGGCCCAGAG ATCCTCTGCT 
TCTGAGAGTG AAACGGAAGA CTCTGATGAT GACAAGAAGC CAAAGCGCAG AGGGCGTCCG 
AGGAGTGTGC GGAAGGACCT CGTGGAGGGA TTTACTGATG CAGAGATCCG AAGGTTCATC 
AAGGCTTATA AGAAGTTTGG TCTCCCTCTT GAACGGCTGG AGTGCATAGC ACGTGATGCT 
GAGCTGGTAG ATAAGTCGGT GGCAGATCTG AAGCGCCTGG GTGAACTGAT CCACAACAGC 
TGTGTGTCAG CAATGCAGGA ATACGAAGAG CAGCTGAAAG AAAATGCCAG CGAGGGAAAA 
GGACCAGGGA AAAGGAGAGG TCCAACAATC AAGATATCCG GAGTTCAGGT TAATGTGAAA 
TCCATTATCC AACATGAAGA GGAGTTTGAG ATGCTGCATA AATCTATCCC TGTGGACCCT 
GAAGAAAAAA AAAAATACTG CTTAACCTGT CGTGTCAAAG CTGCACATTT TGATGTAGAG 
TGGGGGGTGG AAGATGATTC TCGCCTGTTG CTGGGGATTT ATGAACATGG CTATGGAAAC 
TGGGAGTTAA TTAAAACAGA CCCAGAGCTT AAATTAACTG ACAAAATTCT GCCGGTGGAG 
ACAGATAAAA AGCCTCAGGG GAAGCAGCTA CAGACCCGAG CGGATTACTT GTTGAAGCTG 
CTCAGAAAGG GTCTGGAGAA GAAGGGGGCT GTGACAGGTG GGGAAGAGGC CAAATTAAAG 
AAGCGGAAGC CTCGGGTAAA GAAGGAAAAC AAAGTGCCCA GGCTGAAAGA GGAGCATGGA 
ATTGAGCTTT CATCTCCTAG GCATTCAGAT AATCCATCAG AAGAGGGAGA AGTGAAAGAT 
GATGGCTTGG AAAAAAGTCC AATGAAAAAA AAACAGAAGA AGAAAGAGAA CAAGGAGAAC 
AAGGAGAAAC AAATGAGTTC TAGGAAAGAC AAAGAAGGGG ACAAGGAAAG AAAGAAGTCA 
AAAGATAAGA AAGAGAAGCC TAAAAGTGGT GATGCCAAAT CTTCGAGTAA ATCAAAGCGA 
TCTCAGGGTC CTGTCCATAT TACAGCAGGA AGTGAACCTG TCCCCATTGG AGAGGATGAG 
GATGATGATC TGGACCAGGA GACATTCAGC ATATGTAAGG AGAGGATGAG GCCCGTGAAA 
AAGGCACTGA AACAGCTCGA CAAACCTGAC AAGGGGCTCA ACGTGCAAGA ACAGCTGGAA 
CACACCCGGA ACTGCCTGCT GAAAATCGGA GACCGGATAG CCGAGTGCCT TAAAGCCTAC 
TCAGATCAGG AGCACATCAA ACTCTGGAGG AGGAACCTAT GGATTTTTGT TTCCAAGTTT 
ACAGAATTTG ATGCTCGAAA ACTGCATAAG TTATACAAGA TGGCTCATAA GAAAAGGTCT 
CAAGAAGAAG AGGAGCAAAA GAAGAAAGAC GACGTGACTG GGGGTAAGAA ACCATTTCGT 
CCAGAGGCCT CAGGCTCCAG CCGGGACTCT CTGATATCTC AGTCCCATAC CTCACACAAC 
CTTCACCCTC AGAAGCCTCA TTTGCCTGCC TCCCATGGCC CACAGATGCA TGGACACCCA 
AGAGATAACT ACAATCACCC CAACAAGAGA CACTTCAGTA ATGCAGATCG AGGAGACTGG 
CAGAGGGAAA GAAAGTTCAA CTATGGTGGT GGCAACAACA ATCCACCATG GGGAAGCGAC 
AGGCACCATC AGTATGAGCA GCACTGGTAC AAGGACCACC ATTATGGGGA CCGGCGACAT 
ATGGATGCCC ACCGTTCCGG AAGCTATCGA CCCAACAACA TGTCCAGAAA GAGGCCTTAT 
GACCAGTACA GCAGTGACCG AGACCACCGG GGACACAGAG ATTATTATGA CAGGCACCAT 
CATGACTCCA AGCGGAGGAG ATCCGATGAA TTTAGGCCTC AAAATTACCA CCAGCAGGAT 
TTCCGACGAA TGTCTGATCA CCGCCCCGCT ATGGGCTACC ATGGCCAGGG ACCCTCAGAC 
CATTACCGCT CTTTCCACAC AGATAAACTG GGGGAATATA AACAGCCTCT ACCCCCATTG 
CACCCTGCAG TCTCAGATCC TCGCTCACCC CCTTCTCAGA AATCTCCTCA CGATTCCAAG 
TCACCCCTGG ATCATAGGTC TCCTTTGGAG AGATCACTAG AACAGAAAAA CAACCCAGAT 
TATAACTGGA ATGTTCGGAA AACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CHD2 ( NM_001271.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001262.3 Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 1, mRNA.

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CloneID	OHu25723
Clone ID Related Accession (Same CDS sequence)	NM_001271.4 , NM_001271.3
Accession Version	NM_001271.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5487bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	chromodomain-helicase-DNA-binding protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF006514.1, DB121252.1, AC013394.12, DB111282.1, CT003638.1 and AA907775.1. This sequence is a reference standard in the RefSeqGene project. On Nov 28, 2006 this sequence version replaced NM_001271.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGAGAA ATAAGGACAA AAGCCAAGAG GAGGACAGTT CGCTACACAG CAATGCATCG 
AGTCACTCAG CCTCTGAAGA AGCTTCGGGT TCAGACTCAG GCAGTCAGTC GGAAAGTGAG 
CAGGGAAGTG ATCCAGGAAG TGGACATGGC AGCGAGTCGA ACAGCAGCTC TGAATCTTCT 
GAGAGTCAGT CGGAATCTGA GAGCGAATCA GCAGGTTCCA AATCCCAGCC AGTCCTCCCA 
GAAGCCAAAG AGAAGCCAGC CTCTAAGAAG GAACGGATAG CTGATGTGAA GAAGATGTGG 
GAAGAATATC CTGATGTTTA TGGGGTCAGG CGGTCAAACC GAAGCAGACA AGAACCATCG 
CGATTTAATA TTAAGGAAGA GGCAAGTAGC GGGTCTGAGA GTGGGAGCCC AAAAAGAAGA 
GGCCAGAGGC AGCTGAAAAA ACAAGAAAAA TGGAAACAGG AACCCTCAGA AGATGAACAG 
GAACAAGGCA CCAGTGCAGA GAGTGAGCCA GAACAAAAAA AAGTAAAAGC CAGAAGACCT 
GTCCCCAGAA GAACAGTGCC CAAACCTCGT GTTAAAAAGC AGCCGAAGAC TCAGCGTGGA 
AAGAGAAAAA AGCAAGATTC TTCTGATGAG GATGATGATG ATGACGAAGC TCCCAAAAGG 
CAGACTCGTC GAAGAGCGGC TAAAAACGTT AGTTACAAAG AAGATGATGA CTTTGAGACT 
GACTCAGATG ATCTCATTGA AATGACTGGA GAAGGAGTTG ATGAACAGCA AGATAATAGT 
GAAACTATTG AAAAGGTCTT AGATTCAAGA CTGGGAAAGA AAGGAGCCAC TGGAGCATCT 
ACTACTGTAT ATGCGATTGA AGCTAATGGC GACCCTAGTG GTGACTTTGA CACTGAAAAG 
GATGAAGGTG AAATCCAGTA CCTCATCAAG TGGAAGGGTT GGTCTTACAT CCACAGCACA 
TGGGAGAGTG AAGAATCCTT ACAGCAACAG AAAGTGAAGG GCCTAAAAAA ACTAGAGAAC 
TTCAAGAAAA AAGAGGACGA AATCAAACAA TGGTTAGGGA AAGTTTCTCC TGAAGATGTA 
GAATATTTCA ATTGCCAACA GGAGCTGGCT TCAGAGTTGA ATAAACAGTA TCAGATAGTA 
GAAAGAGTAA TAGCTGTGAA GACAAGTAAA TCTACATTGG GTCAAACAGA TTTTCCAGCT 
CATAGTCGGA AGCCGGCACC CTCAAATGAG CCCGAATATC TATGTAAATG GATGGGACTC 
CCCTATTCAG AGTGTAGCTG GGAAGATGAA GCCCTCATTG GAAAGAAATT CCAGAATTGC 
ATTGACAGCT TCCACAGTAG GAACAACTCA AAAACCATCC CAACAAGAGA ATGCAAGGCC 
CTGAAGCAGA GACCACGATT TGTAGCTTTA AAGAAACAAC CTGCATATTT AGGAGGGGAG 
AATCTGGAAC TTCGAGATTA TCAGCTAGAA GGTCTAAACT GGCTAGCTCA TTCCTGGTGC 
AAAAATAATA GTGTAATCCT TGCTGATGAA ATGGGCCTAG GAAAGACCAT CCAGACCATA 
TCATTCCTCT CCTACCTGTT CCACCAACAC CAGCTGTATG GCCCCTTTCT TATAGTCGTC 
CCTTTATCCA CCCTCACCTC ATGGCAGAGA GAGTTTGAAA TCTGGGCACC AGAGATTAAC 
GTAGTGGTTT ACATAGGTGA CCTGATGAGC AGAAATACGA TACGGGAATA TGAATGGATT 
CATTCCCAAA CCAAAAGATT GAAGTTCAAC GCACTTATAA CAACATATGA GATCCTCTTG 
AAAGATAAGA CTGTGCTGGG CAGTATTAAC TGGGCCTTTC TGGGAGTGGA TGAAGCCCAT 
CGGTTGAAGA ATGATGACTC TTTATTGTAT AAAACTCTGA TTGATTTCAA GTCCAACCAT 
AGGCTCCTGA TTACGGGGAC CCCTCTTCAG AATTCCCTCA AAGAGCTCTG GTCCTTGCTG 
CACTTTATTA TGCCGGAGAA GTTTGAATTT TGGGAAGATT TTGAAGAAGA CCATGGGAAG 
GGGAGAGAAA ATGGCTACCA GAGTCTTCAT AAGGTGCTAG AGCCTTTCCT TCTCCGGAGA 
GTCAAAAAAG ATGTGGAGAA ATCCCTTCCT GCTAAAGTGG AACAGATTCT CAGGGTGGAG 
ATGTCAGCCC TTCAGAAACA GTATTACAAG TGGATTCTGA CCAGGAATTA CAAGGCTCTT 
GCCAAAGGAA CAAGAGGCAG CACATCTGGT TTTCTTAATA TTGTGATGGA ACTGAAAAAA 
TGTTGCAACC ACTGCTATCT GATTAAACCC CCTGAAGAAA ATGAAAGGGA AAATGGACAG 
GAGATTCTTC TGTCCCTCAT AAGGAGCAGT GGGAAGTTGA TTTTATTAGA CAAACTGTTG 
ACAAGACTTC GAGAAAGGGG GAATCGAGTG CTTATCTTCT CTCAGATGGT GAGAATGTTG 
GATATCCTGG CTGAATACCT AACTATTAAA CACTATCCTT TCCAGCGTCT GGATGGTTCC 
ATCAAGGGAG AAATCCGAAA ACAGGCACTG GACCACTTCA ATGCAGATGG GTCTGAGGAC 
TTCTGTTTCC TGCTCTCGAC AAGGGCTGGT GGCCTGGGAA TCAATTTGGC TTCAGCGGAC 
ACAGTCGTCA TCTTTGACTC TGACTGGAAC CCCCAGAATG ACTTGCAGGC ACAAGCCCGA 
GCGCATAGAA TTGGTCAAAA GAAGCAGGTA AATATTTACC GCTTAGTTAC AAAGGGGACT 
GTGGAGGAGG AGATCATAGA ACGGGCCAAA AAGAAGATGG TATTAGATCA TCTGGTGATT 
CAGCGCATGG ACACCACTGG CCGGACGATC CTGGAAAACA ACTCAGGAAG GTCCAACTCA 
AATCCTTTTA ATAAAGAAGA GCTGACAGCT ATTTTGAAAT TTGGAGCAGA GGATCTCTTC 
AAAGAACTGG AAGGGGAGGA ATCAGAACCT CAGGAAATGG ATATAGATGA AATTTTGCGG 
TTGGCTGAAA CGAGAGAGAA TGAAGTGTCA ACAAGTGCAA CAGATGAACT TCTATCACAG 
TTTAAGGTTG CCAACTTTGC AACAATGGAA GATGAAGAAG AGCTAGAAGA GCGTCCTCAC 
AAGGACTGGG ATGAGATCAT TCCAGAGGAA CAAAGGAAAA AAGTAGAGGA GGAAGAGCGG 
CAGAAGGAGC TAGAAGAAAT TTATATGCTG CCTCGAATTC GGAGTTCCAC TAAAAAGGCT 
CAGACAAATG ACAGTGACTC TGACACTGAG TCTAAGAGGC AGGCCCAGAG ATCCTCTGCT 
TCTGAGAGTG AAACGGAAGA CTCTGATGAT GACAAGAAGC CAAAGCGCAG AGGGCGTCCG 
AGGAGTGTGC GGAAGGACCT CGTGGAGGGA TTTACTGATG CAGAGATCCG AAGGTTCATC 
AAGGCTTATA AGAAGTTTGG TCTCCCTCTT GAACGGCTGG AGTGCATAGC ACGTGATGCT 
GAGCTGGTAG ATAAGTCGGT GGCAGATCTG AAGCGCCTGG GTGAACTGAT CCACAACAGC 
TGTGTGTCAG CAATGCAGGA ATACGAAGAG CAGCTGAAAG AAAATGCCAG CGAGGGAAAA 
GGACCAGGGA AAAGGAGAGG TCCAACAATC AAGATATCCG GAGTTCAGGT TAATGTGAAA 
TCCATTATCC AACATGAAGA GGAGTTTGAG ATGCTGCATA AATCTATCCC TGTGGACCCT 
GAAGAAAAAA AAAAATACTG CTTAACCTGT CGTGTCAAAG CTGCACATTT TGATGTAGAG 
TGGGGGGTGG AAGATGATTC TCGCCTGTTG CTGGGGATTT ATGAACATGG CTATGGAAAC 
TGGGAGTTAA TTAAAACAGA CCCAGAGCTT AAATTAACTG ACAAAATTCT GCCGGTGGAG 
ACAGATAAAA AGCCTCAGGG GAAGCAGCTA CAGACCCGAG CGGATTACTT GTTGAAGCTG 
CTCAGAAAGG GTCTGGAGAA GAAGGGGGCT GTGACAGGTG GGGAAGAGGC CAAATTAAAG 
AAGCGGAAGC CTCGGGTAAA GAAGGAAAAC AAAGTGCCCA GGCTGAAAGA GGAGCATGGA 
ATTGAGCTTT CATCTCCTAG GCATTCAGAT AATCCATCAG AAGAGGGAGA AGTGAAAGAT 
GATGGCTTGG AAAAAAGTCC AATGAAAAAA AAACAGAAGA AGAAAGAGAA CAAGGAGAAC 
AAGGAGAAAC AAATGAGTTC TAGGAAAGAC AAAGAAGGGG ACAAGGAAAG AAAGAAGTCA 
AAAGATAAGA AAGAGAAGCC TAAAAGTGGT GATGCCAAAT CTTCGAGTAA ATCAAAGCGA 
TCTCAGGGTC CTGTCCATAT TACAGCAGGA AGTGAACCTG TCCCCATTGG AGAGGATGAG 
GATGATGATC TGGACCAGGA GACATTCAGC ATATGTAAGG AGAGGATGAG GCCCGTGAAA 
AAGGCACTGA AACAGCTCGA CAAACCTGAC AAGGGGCTCA ACGTGCAAGA ACAGCTGGAA 
CACACCCGGA ACTGCCTGCT GAAAATCGGA GACCGGATAG CCGAGTGCCT TAAAGCCTAC 
TCAGATCAGG AGCACATCAA ACTCTGGAGG AGGAACCTAT GGATTTTTGT TTCCAAGTTT 
ACAGAATTTG ATGCTCGAAA ACTGCATAAG TTATACAAGA TGGCTCATAA GAAAAGGTCT 
CAAGAAGAAG AGGAGCAAAA GAAGAAAGAC GACGTGACTG GGGGTAAGAA ACCATTTCGT 
CCAGAGGCCT CAGGCTCCAG CCGGGACTCT CTGATATCTC AGTCCCATAC CTCACACAAC 
CTTCACCCTC AGAAGCCTCA TTTGCCTGCC TCCCATGGCC CACAGATGCA TGGACACCCA 
AGAGATAACT ACAATCACCC CAACAAGAGA CACTTCAGTA ATGCAGATCG AGGAGACTGG 
CAGAGGGAAA GAAAGTTCAA CTATGGTGGT GGCAACAACA ATCCACCATG GGGAAGCGAC 
AGGCACCATC AGTATGAGCA GCACTGGTAC AAGGACCACC ATTATGGGGA CCGGCGACAT 
ATGGATGCCC ACCGTTCCGG AAGCTATCGA CCCAACAACA TGTCCAGAAA GAGGCCTTAT 
GACCAGTACA GCAGTGACCG AGACCACCGG GGACACAGAG ATTATTATGA CAGGCACCAT 
CATGACTCCA AGCGGAGGAG ATCCGATGAA TTTAGGCCTC AAAATTACCA CCAGCAGGAT 
TTCCGACGAA TGTCTGATCA CCGCCCCGCT ATGGGCTACC ATGGCCAGGG ACCCTCAGAC 
CATTACCGCT CTTTCCACAC AGATAAACTG GGGGAATATA AACAGCCTCT ACCCCCATTG 
CACCCTGCAG TCTCAGATCC TCGCTCACCC CCTTCTCAGA AATCTCCTCA CGATTCCAAG 
TCACCCCTGG ATCATAGGTC TCCTTTGGAG AGATCACTAG AACAGAAAAA CAACCCAGAT 
TATAACTGGA ATGTTCGGAA AACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001262.3
CDS	576..6062
Translation	MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIKPPEENERENGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRSQEEEEQKKKDDVTGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKPHLPASHGPQMHGHPRDNYNHPNKRHFSNADRGDWQRERKFNYGGGNNNPPWGSDRHHQYEQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYDQYSSDRDHRGHRDYYDRHHHDSKRRRSDEFRPQNYHQQDFRRMSDHRPAMGYHGQGPSDHYRSFHTDKLGEYKQPLPPLHPAVSDPRSPPSQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT

Target ORF information:

RefSeq Version	NM_001271.3
Organism	Homo sapiens(human)
Definition	Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271.3

ORF Insert Sequence:

ATGATGAGAA ATAAGGACAA AAGCCAAGAG GAGGACAGTT CGCTACACAG CAATGCATCG 
AGTCACTCAG CCTCTGAAGA AGCTTCGGGT TCAGACTCAG GCAGTCAGTC GGAAAGTGAG 
CAGGGAAGTG ATCCAGGAAG TGGACATGGC AGCGAGTCGA ACAGCAGCTC TGAATCTTCT 
GAGAGTCAGT CGGAATCTGA GAGCGAATCA GCAGGTTCCA AATCCCAGCC AGTCCTCCCA 
GAAGCCAAAG AGAAGCCAGC CTCTAAGAAG GAACGGATAG CTGATGTGAA GAAGATGTGG 
GAAGAATATC CTGATGTTTA TGGGGTCAGG CGGTCAAACC GAAGCAGACA AGAACCATCG 
CGATTTAATA TTAAGGAAGA GGCAAGTAGC GGGTCTGAGA GTGGGAGCCC AAAAAGAAGA 
GGCCAGAGGC AGCTGAAAAA ACAAGAAAAA TGGAAACAGG AACCCTCAGA AGATGAACAG 
GAACAAGGCA CCAGTGCAGA GAGTGAGCCA GAACAAAAAA AAGTAAAAGC CAGAAGACCT 
GTCCCCAGAA GAACAGTGCC CAAACCTCGT GTTAAAAAGC AGCCGAAGAC TCAGCGTGGA 
AAGAGAAAAA AGCAAGATTC TTCTGATGAG GATGATGATG ATGACGAAGC TCCCAAAAGG 
CAGACTCGTC GAAGAGCGGC TAAAAACGTT AGTTACAAAG AAGATGATGA CTTTGAGACT 
GACTCAGATG ATCTCATTGA AATGACTGGA GAAGGAGTTG ATGAACAGCA AGATAATAGT 
GAAACTATTG AAAAGGTCTT AGATTCAAGA CTGGGAAAGA AAGGAGCCAC TGGAGCATCT 
ACTACTGTAT ATGCGATTGA AGCTAATGGC GACCCTAGTG GTGACTTTGA CACTGAAAAG 
GATGAAGGTG AAATCCAGTA CCTCATCAAG TGGAAGGGTT GGTCTTACAT CCACAGCACA 
TGGGAGAGTG AAGAATCCTT ACAGCAACAG AAAGTGAAGG GCCTAAAAAA ACTAGAGAAC 
TTCAAGAAAA AAGAGGACGA AATCAAACAA TGGTTAGGGA AAGTTTCTCC TGAAGATGTA 
GAATATTTCA ATTGCCAACA GGAGCTGGCT TCAGAGTTGA ATAAACAGTA TCAGATAGTA 
GAAAGAGTAA TAGCTGTGAA GACAAGTAAA TCTACATTGG GTCAAACAGA TTTTCCAGCT 
CATAGTCGGA AGCCGGCACC CTCAAATGAG CCCGAATATC TATGTAAATG GATGGGACTC 
CCCTATTCAG AGTGTAGCTG GGAAGATGAA GCCCTCATTG GAAAGAAATT CCAGAATTGC 
ATTGACAGCT TCCACAGTAG GAACAACTCA AAAACCATCC CAACAAGAGA ATGCAAGGCC 
CTGAAGCAGA GACCACGATT TGTAGCTTTA AAGAAACAAC CTGCATATTT AGGAGGGGAG 
AATCTGGAAC TTCGAGATTA TCAGCTAGAA GGTCTAAACT GGCTAGCTCA TTCCTGGTGC 
AAAAATAATA GTGTAATCCT TGCTGATGAA ATGGGCCTAG GAAAGACCAT CCAGACCATA 
TCATTCCTCT CCTACCTGTT CCACCAACAC CAGCTGTATG GCCCCTTTCT TATAGTCGTC 
CCTTTATCCA CCCTCACCTC ATGGCAGAGA GAGTTTGAAA TCTGGGCACC AGAGATTAAC 
GTAGTGGTTT ACATAGGTGA CCTGATGAGC AGAAATACGA TACGGGAATA TGAATGGATT 
CATTCCCAAA CCAAAAGATT GAAGTTCAAC GCACTTATAA CAACATATGA GATCCTCTTG 
AAAGATAAGA CTGTGCTGGG CAGTATTAAC TGGGCCTTTC TGGGAGTGGA TGAAGCCCAT 
CGGTTGAAGA ATGATGACTC TTTATTGTAT AAAACTCTGA TTGATTTCAA GTCCAACCAT 
AGGCTCCTGA TTACGGGGAC CCCTCTTCAG AATTCCCTCA AAGAGCTCTG GTCCTTGCTG 
CACTTTATTA TGCCGGAGAA GTTTGAATTT TGGGAAGATT TTGAAGAAGA CCATGGGAAG 
GGGAGAGAAA ATGGCTACCA GAGTCTTCAT AAGGTGCTAG AGCCTTTCCT TCTCCGGAGA 
GTCAAAAAAG ATGTGGAGAA ATCCCTTCCT GCTAAAGTGG AACAGATTCT CAGGGTGGAG 
ATGTCAGCCC TTCAGAAACA GTATTACAAG TGGATTCTGA CCAGGAATTA CAAGGCTCTT 
GCCAAAGGAA CAAGAGGCAG CACATCTGGT TTTCTTAATA TTGTGATGGA ACTGAAAAAA 
TGTTGCAACC ACTGCTATCT GATTAAACCC CCTGAAGAAA ATGAAAGGGA AAATGGACAG 
GAGATTCTTC TGTCCCTCAT AAGGAGCAGT GGGAAGTTGA TTTTATTAGA CAAACTGTTG 
ACAAGACTTC GAGAAAGGGG GAATCGAGTG CTTATCTTCT CTCAGATGGT GAGAATGTTG 
GATATCCTGG CTGAATACCT AACTATTAAA CACTATCCTT TCCAGCGTCT GGATGGTTCC 
ATCAAGGGAG AAATCCGAAA ACAGGCACTG GACCACTTCA ATGCAGATGG GTCTGAGGAC 
TTCTGTTTCC TGCTCTCGAC AAGGGCTGGT GGCCTGGGAA TCAATTTGGC TTCAGCGGAC 
ACAGTCGTCA TCTTTGACTC TGACTGGAAC CCCCAGAATG ACTTGCAGGC ACAAGCCCGA 
GCGCATAGAA TTGGTCAAAA GAAGCAGGTA AATATTTACC GCTTAGTTAC AAAGGGGACT 
GTGGAGGAGG AGATCATAGA ACGGGCCAAA AAGAAGATGG TATTAGATCA TCTGGTGATT 
CAGCGCATGG ACACCACTGG CCGGACGATC CTGGAAAACA ACTCAGGAAG GTCCAACTCA 
AATCCTTTTA ATAAAGAAGA GCTGACAGCT ATTTTGAAAT TTGGAGCAGA GGATCTCTTC 
AAAGAACTGG AAGGGGAGGA ATCAGAACCT CAGGAAATGG ATATAGATGA AATTTTGCGG 
TTGGCTGAAA CGAGAGAGAA TGAAGTGTCA ACAAGTGCAA CAGATGAACT TCTATCACAG 
TTTAAGGTTG CCAACTTTGC AACAATGGAA GATGAAGAAG AGCTAGAAGA GCGTCCTCAC 
AAGGACTGGG ATGAGATCAT TCCAGAGGAA CAAAGGAAAA AAGTAGAGGA GGAAGAGCGG 
CAGAAGGAGC TAGAAGAAAT TTATATGCTG CCTCGAATTC GGAGTTCCAC TAAAAAGGCT 
CAGACAAATG ACAGTGACTC TGACACTGAG TCTAAGAGGC AGGCCCAGAG ATCCTCTGCT 
TCTGAGAGTG AAACGGAAGA CTCTGATGAT GACAAGAAGC CAAAGCGCAG AGGGCGTCCG 
AGGAGTGTGC GGAAGGACCT CGTGGAGGGA TTTACTGATG CAGAGATCCG AAGGTTCATC 
AAGGCTTATA AGAAGTTTGG TCTCCCTCTT GAACGGCTGG AGTGCATAGC ACGTGATGCT 
GAGCTGGTAG ATAAGTCGGT GGCAGATCTG AAGCGCCTGG GTGAACTGAT CCACAACAGC 
TGTGTGTCAG CAATGCAGGA ATACGAAGAG CAGCTGAAAG AAAATGCCAG CGAGGGAAAA 
GGACCAGGGA AAAGGAGAGG TCCAACAATC AAGATATCCG GAGTTCAGGT TAATGTGAAA 
TCCATTATCC AACATGAAGA GGAGTTTGAG ATGCTGCATA AATCTATCCC TGTGGACCCT 
GAAGAAAAAA AAAAATACTG CTTAACCTGT CGTGTCAAAG CTGCACATTT TGATGTAGAG 
TGGGGGGTGG AAGATGATTC TCGCCTGTTG CTGGGGATTT ATGAACATGG CTATGGAAAC 
TGGGAGTTAA TTAAAACAGA CCCAGAGCTT AAATTAACTG ACAAAATTCT GCCGGTGGAG 
ACAGATAAAA AGCCTCAGGG GAAGCAGCTA CAGACCCGAG CGGATTACTT GTTGAAGCTG 
CTCAGAAAGG GTCTGGAGAA GAAGGGGGCT GTGACAGGTG GGGAAGAGGC CAAATTAAAG 
AAGCGGAAGC CTCGGGTAAA GAAGGAAAAC AAAGTGCCCA GGCTGAAAGA GGAGCATGGA 
ATTGAGCTTT CATCTCCTAG GCATTCAGAT AATCCATCAG AAGAGGGAGA AGTGAAAGAT 
GATGGCTTGG AAAAAAGTCC AATGAAAAAA AAACAGAAGA AGAAAGAGAA CAAGGAGAAC 
AAGGAGAAAC AAATGAGTTC TAGGAAAGAC AAAGAAGGGG ACAAGGAAAG AAAGAAGTCA 
AAAGATAAGA AAGAGAAGCC TAAAAGTGGT GATGCCAAAT CTTCGAGTAA ATCAAAGCGA 
TCTCAGGGTC CTGTCCATAT TACAGCAGGA AGTGAACCTG TCCCCATTGG AGAGGATGAG 
GATGATGATC TGGACCAGGA GACATTCAGC ATATGTAAGG AGAGGATGAG GCCCGTGAAA 
AAGGCACTGA AACAGCTCGA CAAACCTGAC AAGGGGCTCA ACGTGCAAGA ACAGCTGGAA 
CACACCCGGA ACTGCCTGCT GAAAATCGGA GACCGGATAG CCGAGTGCCT TAAAGCCTAC 
TCAGATCAGG AGCACATCAA ACTCTGGAGG AGGAACCTAT GGATTTTTGT TTCCAAGTTT 
ACAGAATTTG ATGCTCGAAA ACTGCATAAG TTATACAAGA TGGCTCATAA GAAAAGGTCT 
CAAGAAGAAG AGGAGCAAAA GAAGAAAGAC GACGTGACTG GGGGTAAGAA ACCATTTCGT 
CCAGAGGCCT CAGGCTCCAG CCGGGACTCT CTGATATCTC AGTCCCATAC CTCACACAAC 
CTTCACCCTC AGAAGCCTCA TTTGCCTGCC TCCCATGGCC CACAGATGCA TGGACACCCA 
AGAGATAACT ACAATCACCC CAACAAGAGA CACTTCAGTA ATGCAGATCG AGGAGACTGG 
CAGAGGGAAA GAAAGTTCAA CTATGGTGGT GGCAACAACA ATCCACCATG GGGAAGCGAC 
AGGCACCATC AGTATGAGCA GCACTGGTAC AAGGACCACC ATTATGGGGA CCGGCGACAT 
ATGGATGCCC ACCGTTCCGG AAGCTATCGA CCCAACAACA TGTCCAGAAA GAGGCCTTAT 
GACCAGTACA GCAGTGACCG AGACCACCGG GGACACAGAG ATTATTATGA CAGGCACCAT 
CATGACTCCA AGCGGAGGAG ATCCGATGAA TTTAGGCCTC AAAATTACCA CCAGCAGGAT 
TTCCGACGAA TGTCTGATCA CCGCCCCGCT ATGGGCTACC ATGGCCAGGG ACCCTCAGAC 
CATTACCGCT CTTTCCACAC AGATAAACTG GGGGAATATA AACAGCCTCT ACCCCCATTG 
CACCCTGCAG TCTCAGATCC TCGCTCACCC CCTTCTCAGA AATCTCCTCA CGATTCCAAG 
TCACCCCTGG ATCATAGGTC TCCTTTGGAG AGATCACTAG AACAGAAAAA CAACCCAGAT 
TATAACTGGA ATGTTCGGAA AACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Autism spectrum disorder recurrence, resulting of germline mosaicism for a CHD2 gene missense variant.
Clinical genetics92(6)669-670(2017 Dec)
Lebrun N,Parent P,Gendras J,Billuart P,Poirier K,Bienvenu T

Exome sequencing analysis in a pair of monozygotic twins re-evaluates the genetics behind their intellectual disability and reveals a CHD2 mutation.
Brain & development38(6)590-6(2016 Jun)
Pinto AM,Bianciardi L,Mencarelli MA,Imperatore V,Di Marco C,Furini S,Suppiej A,Salviati L,Tenconi R,Ariani F,Mari F,Renieri A

PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining.
Molecular cell61(4)547-562(2016 Feb)
Luijsterburg MS,de Krijger I,Wiegant WW,Shah RG,Smeenk G,de Groot AJL,Pines A,Vertegaal ACO,Jacobs JJL,Shah GM,van Attikum H

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CHD2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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