Gene Symbol | UBA2 |
Entrez Gene ID | 10054 |
Full Name | ubiquitin like modifier activating enzyme 2 |
Synonyms | ARX,HRIHFB2115,SAE2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]. |
Disorder MIM: |