mvk cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	mvk
Entrez Gene ID	492477
Full Name	mevalonate kinase
Synonyms	zgc:103473
General protein information	Preferred Names mevalonate kinase Names mevalonate kinase
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001007349.1	NP_001007350.1	mevalonate kinase

Pathways from BioSystems

Homologies

	MVK	XP_001105815.1
Canis lupus familiaris (dog)	MVK	XP_005636378.1
Schizosaccharomyces pombe (fission yeast)	erg12	NP_592837.1
Homo sapiens (human)	MVK	NP_001107657.1
Pan troglodytes (chimpanzee)	MVK	XP_003313983.1
Magnaporthe oryzae (rice blast fungus)	MGG_16219	XP_003709688.1
Xenopus tropicalis (tropical clawed frog)	mvk	XP_002932110.2
Gallus gallus (chicken)	MVK	XP_001231562.3
Danio rerio (zebrafish)	mvk	NP_001007350.1
Neurospora crassa	NCU03633	XP_961360.1
Bos taurus (cattle)	MVK	NP_001015528.1
Mus musculus (house mouse)	Mvk	NP_076045.1
Rattus norvegicus (Norway rat)	Mvk	NP_112325.1
Kluyveromyces lactis	KLLA0C07469g	XP_452532.1
Eremothecium gossypii	AGOS_AER335W	NP_985191.1
Gallus gallus (chicken)	LOC100857437	XP_003643684.2
Caenorhabditis elegans (roundworm)	mvk-1	NP_001022869.1
Saccharomyces cerevisiae (baker's yeast)	ERG12	NP_013935.1
Arabidopsis thaliana (thale cress)	MK	NP_198097.1
Oryza sativa (rice)	Os10g0329300	NP_001064360.1

Gene Ontology
Bibliography

Related articles in PubMed

trappc11 is required for protein glycosylation in zebrafish and humans.
DeRossi C, Vacaru A, Rafiq R, Cinaroglu A, Imrie D, Nayar S, Baryshnikova A, Milev MP, Stanga D, Kadakia D, Gao N, Chu J, Freeze HH, Lehrman MA, Sacher M, Sadler KC
Molecular biology of the cell27(8)1220-34(2016 Apr)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

The draft genome of the grass carp (Ctenopharyngodon idellus) provides insights into its evolution and vegetarian adaptation.
Wang Y, Lu Y, Zhang Y, Ning Z, Li Y, Zhao Q, Lu H, Huang R, Xia X, Feng Q, Liang X, Liu K, Zhang L, Lu T, Huang T, Fan D, Weng Q, Zhu C, Lu Y, Li W, Wen Z, Zhou C, Tian Q, Kang X, Shi M, Zhang W, Jang S, Du F, He S, Liao L, Li Y, Gui B, He H, Ning Z, Yang C, He L, Luo L, Yang R, Luo Q, Liu X, Li S, Huang W, Xiao L, Lin H, Han B, Zhu Z
Nature genetics47(6)625-31(2015 Jun)

Activating transcription factor 6 is necessary and sufficient for alcoholic fatty liver disease in zebrafish.
Howarth DL, Lindtner C, Vacaru AM, Sachidanandam R, Tsedensodnom O, Vasilkova T, Buettner C, Sadler KC
PLoS genetics10(5)e1004335(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following mvk gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mvk cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa04402	NM_001007349.1 Latest version!	Danio rerio mevalonate kinase (mvk), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

mvk ( NM_001007349.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001007350.1 Danio rerio mevalonate kinase (mvk), mRNA.

Price & Availability↑

CloneID	ODa04402
Clone ID Related Accession (Same CDS sequence)	NM_001007349.1
Accession Version	NM_001007349.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-08
Organism	Danio rerio(zebrafish)
Product	mevalonate kinase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085528.1. ##Evidence-Data-START## Transcript exon combination :: BC085528.1, BC164491.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGCAAAGCA GAGAGTTGTT CGTTTCAGCA CCTGGGAAAG TAATTCTCCA CGGCGAGCAT 
TCTGTCGTGC ATGGGAAGGT TGCCTTGGCT GTGAGTGTGA ATCTGCGCAC ATACCTGCGG 
CTGCAGTCCA CGTCATCTGG TCAAGTGTGC ATCAACCTCC CCAATATTGA CACTTTTCTG 
TCCTGGGAAA TAACTGCACT GCAGCCTCTA CTTGCTGGCT CTAAAGCTGA GCAGAGGGAC 
CCCAAGGAAC TTGATGCAGA TCTTTTGAAG AAACTCAGAG AATTCACTGG CATTTCAGAT 
GATTCCACAG ACACAAGGAG CATGGCAGTG TTGGCTTTTC TCTACATGTA CCTCACTGTT 
TTTGCAGAGT CTTTGGCCAG TATCACAGTG TCTGTGTGGT CAGAGTTGCC CACAGGAGCT 
GGTTTAGGCT CCAGTGCTGC CTATAATGTT TGTCTGTCTG CTGCATTGCT GTCTGCTAGA 
GGAAACATAT CACCTCTGCT TATGGCTCAG CAGGAGTCTG CCAGGTGGAG TAAAGATGAG 
ATGGAGCTGA TTAACAGGTG GGCGTTCATG GGTGAGAAGA TCATTCATGG TAACCCTTCA 
GGGGTGGACA ATGCTGTGGG CACATGGGGT GGTTTCTTAA GATATCATTC TGGAAATATA 
ACTCCATTAA GCTGGGTTCC CATTTTGAGG ATACTTCTCA CTAACACCAA AGTACCACGT 
AGTACCAAAG TGCTTGTTTC TGGAGTGAAG GACAAAATTA ACAAGTTTCC CTCTGTAATG 
AGGCCAGTTC TGGAGTCAGT GAGTGCAGTG TCCTGCACTT GTGAACAGAC ACTCACTGAG 
ATGGCAGAAC ACGGACCTTC AGCTGAACAC TACAACATAC TCGAGGAGCT GATTGATATA 
AACCAGCATC ATCTGAATGT GATGGGTGTG GGTCACTCAT CTCTGGACAC ACTGTGTAGA 
GTAACTCTGT CCAAAGGGCT ACACAGCAAA CTGACAGGGG CAGGAGGAGG AGGGTGTGGA 
ATCACACTTT TGCGACCAGA GACTGATACT TCAGTGATTC AGAGCGCTGT TGAGGAGCTG 
AAGGCCTGTG GGTTTGACTG CTGGGAGACC AGTATCGGAG CTCCTGGTGT ACAACAACAC 
TCTTCTGCTG CTATCAGTCC AGATGTGCTG AAGATCCTTA ACAGCTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007350.1
CDS	207..1397
Translation	MQSRELFVSAPGKVILHGEHSVVHGKVALAVSVNLRTYLRLQSTSSGQVCINLPNIDTFLSWEITALQPLLAGSKAEQRDPKELDADLLKKLREFTGISDDSTDTRSMAVLAFLYMYLTVFAESLASITVSVWSELPTGAGLGSSAAYNVCLSAALLSARGNISPLLMAQQESARWSKDEMELINRWAFMGEKIIHGNPSGVDNAVGTWGGFLRYHSGNITPLSWVPILRILLTNTKVPRSTKVLVSGVKDKINKFPSVMRPVLESVSAVSCTCEQTLTEMAEHGPSAEHYNILEELIDINQHHLNVMGVGHSSLDTLCRVTLSKGLHSKLTGAGGGGCGITLLRPETDTSVIQSAVEELKACGFDCWETSIGAPGVQQHSSAAISPDVLKILNSY

Target ORF information:

RefSeq Version	NM_001007349.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio mevalonate kinase (mvk), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007349.1

ORF Insert Sequence:

ATGCAAAGCA GAGAGTTGTT CGTTTCAGCA CCTGGGAAAG TAATTCTCCA CGGCGAGCAT 
TCTGTCGTGC ATGGGAAGGT TGCCTTGGCT GTGAGTGTGA ATCTGCGCAC ATACCTGCGG 
CTGCAGTCCA CGTCATCTGG TCAAGTGTGC ATCAACCTCC CCAATATTGA CACTTTTCTG 
TCCTGGGAAA TAACTGCACT GCAGCCTCTA CTTGCTGGCT CTAAAGCTGA GCAGAGGGAC 
CCCAAGGAAC TTGATGCAGA TCTTTTGAAG AAACTCAGAG AATTCACTGG CATTTCAGAT 
GATTCCACAG ACACAAGGAG CATGGCAGTG TTGGCTTTTC TCTACATGTA CCTCACTGTT 
TTTGCAGAGT CTTTGGCCAG TATCACAGTG TCTGTGTGGT CAGAGTTGCC CACAGGAGCT 
GGTTTAGGCT CCAGTGCTGC CTATAATGTT TGTCTGTCTG CTGCATTGCT GTCTGCTAGA 
GGAAACATAT CACCTCTGCT TATGGCTCAG CAGGAGTCTG CCAGGTGGAG TAAAGATGAG 
ATGGAGCTGA TTAACAGGTG GGCGTTCATG GGTGAGAAGA TCATTCATGG TAACCCTTCA 
GGGGTGGACA ATGCTGTGGG CACATGGGGT GGTTTCTTAA GATATCATTC TGGAAATATA 
ACTCCATTAA GCTGGGTTCC CATTTTGAGG ATACTTCTCA CTAACACCAA AGTACCACGT 
AGTACCAAAG TGCTTGTTTC TGGAGTGAAG GACAAAATTA ACAAGTTTCC CTCTGTAATG 
AGGCCAGTTC TGGAGTCAGT GAGTGCAGTG TCCTGCACTT GTGAACAGAC ACTCACTGAG 
ATGGCAGAAC ACGGACCTTC AGCTGAACAC TACAACATAC TCGAGGAGCT GATTGATATA 
AACCAGCATC ATCTGAATGT GATGGGTGTG GGTCACTCAT CTCTGGACAC ACTGTGTAGA 
GTAACTCTGT CCAAAGGGCT ACACAGCAAA CTGACAGGGG CAGGAGGAGG AGGGTGTGGA 
ATCACACTTT TGCGACCAGA GACTGATACT TCAGTGATTC AGAGCGCTGT TGAGGAGCTG 
AAGGCCTGTG GGTTTGACTG CTGGGAGACC AGTATCGGAG CTCCTGGTGT ACAACAACAC 
TCTTCTGCTG CTATCAGTCC AGATGTGCTG AAGATCCTTA ACAGCTACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

trappc11 is required for protein glycosylation in zebrafish and humans.
Molecular biology of the cell27(8)1220-34(2016 Apr)
DeRossi C,Vacaru A,Rafiq R,Cinaroglu A,Imrie D,Nayar S,Baryshnikova A,Milev MP,Stanga D,Kadakia D,Gao N,Chu J,Freeze HH,Lehrman MA,Sacher M,Sadler KC

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

The draft genome of the grass carp (Ctenopharyngodon idellus) provides insights into its evolution and vegetarian adaptation.
Nature genetics47(6)625-31(2015 Jun)
Wang Y,Lu Y,Zhang Y,Ning Z,Li Y,Zhao Q,Lu H,Huang R,Xia X,Feng Q,Liang X,Liu K,Zhang L,Lu T,Huang T,Fan D,Weng Q,Zhu C,Lu Y,Li W,Wen Z,Zhou C,Tian Q,Kang X,Shi M,Zhang W,Jang S,Du F,He S,Liao L,Li Y,Gui B,He H,Ning Z,Yang C,He L,Luo L,Yang R,Luo Q,Liu X,Li S,Huang W,Xiao L,Lin H,Han B,Zhu Z

Activating transcription factor 6 is necessary and sufficient for alcoholic fatty liver disease in zebrafish.
PLoS genetics10(5)e1004335(2014)
Howarth DL,Lindtner C,Vacaru AM,Sachidanandam R,Tsedensodnom O,Vasilkova T,Buettner C,Sadler KC

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mvk cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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