MVK gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
XM_011538372.1	XP_011536674.1	mevalonate kinase isoform X1
XM_011538372.2	XP_011536674.2	mevalonate kinase isoform X1
NM_001114185.3	NP_001107657.1	mevalonate kinase isoform a
XM_017019313.2	XP_016874802.1	mevalonate kinase isoform X2
NM_001114185.2	NP_001107657.1	mevalonate kinase isoform a
NM_001301182.1	NP_001288111.1	mevalonate kinase isoform b
NM_001301182.2	NP_001288111.1	mevalonate kinase isoform b
NM_000431.4	NP_000422.1	mevalonate kinase isoform a
XM_017019313.1	XP_016874802.1	mevalonate kinase isoform X2
NM_000431.3	NP_000422.1	mevalonate kinase isoform a
XM_024448982.1	XP_024304750.1	mevalonate kinase isoform X1
XM_017019314.1	XP_016874803.1	mevalonate kinase isoform X3

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24972	NM_001114185.3 Latest version!	Homo sapiens mevalonate kinase (MVK), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu24972	NM_000431.4 Latest version!	Homo sapiens mevalonate kinase (MVK), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu24972	XM_017019314.1 Latest version!	Homo sapiens mevalonate kinase (MVK), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu24972	XM_011538372.1 Latest version!	Homo sapiens mevalonate kinase (MVK), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu46565	NM_001301182.2 Latest version!	Homo sapiens mevalonate kinase (MVK), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu46565	XM_017019313.2 Latest version!	Homo sapiens mevalonate kinase (MVK), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu103728	XM_024448982.1 Latest version!	Homo sapiens mevalonate kinase (MVK), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu83787	XM_011538372.2 Latest version!	Homo sapiens mevalonate kinase (MVK), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu24972	NM_001114185.2	Homo sapiens mevalonate kinase (MVK), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu46565	NM_001301182.1	Homo sapiens mevalonate kinase (MVK), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu46565	XM_017019313.1	Homo sapiens mevalonate kinase (MVK), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu24972	NM_000431.3	Homo sapiens mevalonate kinase (MVK), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

MVK ( NM_001114185.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001107657.1 Homo sapiens mevalonate kinase (MVK), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu24972
Clone ID Related Accession (Same CDS sequence)	XM_011538372.1 , NM_001114185.3 , NM_001114185.2 , NM_000431.4 , NM_000431.3 , XM_017019314.1
Accession Version	NM_001114185.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	mevalonate kinase isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC421549.1, BC016140.1, R51202.1 and AC007570.23. On May 31, 2019 this sequence version replaced NM_001114185.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC016140.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2152719, SAMEA2154361 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001107657.1
CDS	86..1276
Translation	MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

Target ORF information:

RefSeq Version	NM_001114185.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mevalonate kinase (MVK), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001114185.3

ORF Insert Sequence:

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVK ( NM_001114185.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001107657.1 Homo sapiens mevalonate kinase (MVK), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu24972
Clone ID Related Accession (Same CDS sequence)	XM_011538372.1 , NM_001114185.3 , NM_001114185.2 , NM_000431.4 , NM_000431.3 , XM_017019314.1
Accession Version	NM_001114185.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	mevalonate kinase isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC421549.1, BC016140.1 and R51202.1. On Jul 25, 2014 this sequence version replaced NM_001114185.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC016140.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2152719, SAMEA2154361 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001107657.1
CDS	185..1375
Translation	MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

Target ORF information:

RefSeq Version	NM_001114185.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mevalonate kinase (MVK), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001114185.2

ORF Insert Sequence:

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVK ( NM_000431.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000422.1 Homo sapiens mevalonate kinase (MVK), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24972
Clone ID Related Accession (Same CDS sequence)	XM_011538372.1 , NM_001114185.3 , NM_001114185.2 , NM_000431.4 , NM_000431.3 , XM_017019314.1
Accession Version	NM_000431.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	mevalonate kinase isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC421549.1, M88468.1, BC016140.1, R51202.1 and AC007570.23. On Nov 22, 2018 this sequence version replaced NM_000431.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.786103.1, SRR3476690.971180.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000228510.8/ ENSP00000228510.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000422.1
CDS	95..1285
Translation	MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

Target ORF information:

RefSeq Version	NM_000431.4
Organism	Homo sapiens(human)
Definition	Homo sapiens mevalonate kinase (MVK), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000431.4

ORF Insert Sequence:

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVK ( NM_000431.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000422.1 Homo sapiens mevalonate kinase (MVK), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24972
Clone ID Related Accession (Same CDS sequence)	XM_011538372.1 , NM_001114185.3 , NM_001114185.2 , NM_000431.4 , NM_000431.3 , XM_017019314.1
Accession Version	NM_000431.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	mevalonate kinase isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC421549.1, M88468.1, BC016140.1 and R51202.1. On Jul 25, 2014 this sequence version replaced NM_000431.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB209722.1, M88468.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000422.1
CDS	194..1384
Translation	MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

Target ORF information:

RefSeq Version	NM_000431.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mevalonate kinase (MVK), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000431.3

ORF Insert Sequence:

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVK ( XM_011538372.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011536674.1 Homo sapiens mevalonate kinase (MVK), transcript variant X1, mRNA.

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CloneID	OHu24972
Clone ID Related Accession (Same CDS sequence)	XM_011538372.1 , NM_001114185.3 , NM_001114185.2 , NM_000431.4 , NM_000431.3 , XM_017019314.1
Accession Version	XM_011538372.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	mevalonate kinase isoform X1
Comment

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011536674.1
Translation	MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

Target ORF information:

RefSeq Version	XM_011538372.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens mevalonate kinase (MVK), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011538372.1

ORF Insert Sequence:

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVK ( XM_017019314.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874803.1 Homo sapiens mevalonate kinase (MVK), transcript variant X3, mRNA.

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CloneID	OHu24972
Clone ID Related Accession (Same CDS sequence)	XM_011538372.1 , NM_001114185.3 , NM_001114185.2 , NM_000431.4 , NM_000431.3 , XM_017019314.1
Accession Version	XM_017019314.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	mevalonate kinase isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874803.1
CDS	660..1850
Translation	MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

Target ORF information:

RefSeq Version	XM_017019314.1
Organism	Homo sapiens(human)
Definition	Homo sapiens mevalonate kinase (MVK), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017019314.1

ORF Insert Sequence:

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVK ( NM_001301182.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001288111.1 Homo sapiens mevalonate kinase (MVK), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu46565
Clone ID Related Accession (Same CDS sequence)	XM_017019313.2 , NM_001301182.1 , NM_001301182.2 , XM_017019313.1
Accession Version	NM_001301182.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	mevalonate kinase isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC421549.1, AK295338.1, AC007570.23, BC016140.1 and R51202.1. On Jul 25, 2014 this sequence version replaced XM_005253884.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (b) is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.257998.1, AK295338.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGTGGACCAA GGAGGATTTG GAGCTAATTA ACAAGTGGGC CTTCCAAGGG 
GAGAGAATGA TTCACGGGAA CCCCTCCGGA GTGGACAATG CTGTCAGCAC CTGGGGAGGA 
GCCCTCCGAT ACCATCAAGG GAAGATTTCA TCCTTAAAGA GGTCGCCAGC TCTCCAGATC 
CTGCTGACCA ACACCAAAGT CCCTCGCAAT ACCAGGGCCC TTGTGGCTGG CGTCAGAAAC 
AGGCTGCTCA AGTTCCCAGA GATCGTGGCC CCCCTCCTGA CCTCAATAGA TGCCATCTCC 
CTGGAGTGTG AGCGCGTGCT GGGAGAGATG GGGGAAGCCC CAGCCCCGGA GCAGTACCTC 
GTGCTGGAAG AGCTCATTGA CATGAACCAG CACCATCTGA ATGCCCTCGG CGTGGGCCAC 
GCCTCTCTGG ACCAGCTCTG CCAGGTGACC AGGGCCCGCG GACTTCACAG CAAGCTGACT 
GGCGCAGGCG GTGGTGGCTG TGGCATCACA CTCCTCAAGC CAGGGCTGGA GCAGCCAGAA 
GTGGAGGCCA CGAAGCAGGC CCTGACCAGC TGTGGCTTTG ACTGCTTGGA AACCAGCATC 
GGTGCCCCCG GCGTCTCCAT CCACTCAGCC ACCTCCCTGG ACAGCCGAGT CCAGCAAGCC 
CTGGATGGCC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288111.1
CDS	194..1228
Translation	MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

Target ORF information:

RefSeq Version	NM_001301182.1
Organism	Homo sapiens(human)
Definition	Homo sapiens mevalonate kinase (MVK), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301182.1

ORF Insert Sequence:

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGTGGACCAA GGAGGATTTG GAGCTAATTA ACAAGTGGGC CTTCCAAGGG 
GAGAGAATGA TTCACGGGAA CCCCTCCGGA GTGGACAATG CTGTCAGCAC CTGGGGAGGA 
GCCCTCCGAT ACCATCAAGG GAAGATTTCA TCCTTAAAGA GGTCGCCAGC TCTCCAGATC 
CTGCTGACCA ACACCAAAGT CCCTCGCAAT ACCAGGGCCC TTGTGGCTGG CGTCAGAAAC 
AGGCTGCTCA AGTTCCCAGA GATCGTGGCC CCCCTCCTGA CCTCAATAGA TGCCATCTCC 
CTGGAGTGTG AGCGCGTGCT GGGAGAGATG GGGGAAGCCC CAGCCCCGGA GCAGTACCTC 
GTGCTGGAAG AGCTCATTGA CATGAACCAG CACCATCTGA ATGCCCTCGG CGTGGGCCAC 
GCCTCTCTGG ACCAGCTCTG CCAGGTGACC AGGGCCCGCG GACTTCACAG CAAGCTGACT 
GGCGCAGGCG GTGGTGGCTG TGGCATCACA CTCCTCAAGC CAGGGCTGGA GCAGCCAGAA 
GTGGAGGCCA CGAAGCAGGC CCTGACCAGC TGTGGCTTTG ACTGCTTGGA AACCAGCATC 
GGTGCCCCCG GCGTCTCCAT CCACTCAGCC ACCTCCCTGG ACAGCCGAGT CCAGCAAGCC 
CTGGATGGCC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVK ( NM_001301182.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001288111.1 Homo sapiens mevalonate kinase (MVK), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu46565
Clone ID Related Accession (Same CDS sequence)	XM_017019313.2 , NM_001301182.1 , NM_001301182.2 , XM_017019313.1
Accession Version	NM_001301182.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	mevalonate kinase isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC421549.1, AK295338.1, AC007570.23, BC016140.1 and R51202.1. On May 31, 2019 this sequence version replaced NM_001301182.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (b) is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7410570.509229.1, SRR1163655.257998.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGTGGACCAA GGAGGATTTG GAGCTAATTA ACAAGTGGGC CTTCCAAGGG 
GAGAGAATGA TTCACGGGAA CCCCTCCGGA GTGGACAATG CTGTCAGCAC CTGGGGAGGA 
GCCCTCCGAT ACCATCAAGG GAAGATTTCA TCCTTAAAGA GGTCGCCAGC TCTCCAGATC 
CTGCTGACCA ACACCAAAGT CCCTCGCAAT ACCAGGGCCC TTGTGGCTGG CGTCAGAAAC 
AGGCTGCTCA AGTTCCCAGA GATCGTGGCC CCCCTCCTGA CCTCAATAGA TGCCATCTCC 
CTGGAGTGTG AGCGCGTGCT GGGAGAGATG GGGGAAGCCC CAGCCCCGGA GCAGTACCTC 
GTGCTGGAAG AGCTCATTGA CATGAACCAG CACCATCTGA ATGCCCTCGG CGTGGGCCAC 
GCCTCTCTGG ACCAGCTCTG CCAGGTGACC AGGGCCCGCG GACTTCACAG CAAGCTGACT 
GGCGCAGGCG GTGGTGGCTG TGGCATCACA CTCCTCAAGC CAGGGCTGGA GCAGCCAGAA 
GTGGAGGCCA CGAAGCAGGC CCTGACCAGC TGTGGCTTTG ACTGCTTGGA AACCAGCATC 
GGTGCCCCCG GCGTCTCCAT CCACTCAGCC ACCTCCCTGG ACAGCCGAGT CCAGCAAGCC 
CTGGATGGCC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288111.1
CDS	95..1129
Translation	MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

Target ORF information:

RefSeq Version	NM_001301182.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mevalonate kinase (MVK), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301182.2

ORF Insert Sequence:

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGTGGACCAA GGAGGATTTG GAGCTAATTA ACAAGTGGGC CTTCCAAGGG 
GAGAGAATGA TTCACGGGAA CCCCTCCGGA GTGGACAATG CTGTCAGCAC CTGGGGAGGA 
GCCCTCCGAT ACCATCAAGG GAAGATTTCA TCCTTAAAGA GGTCGCCAGC TCTCCAGATC 
CTGCTGACCA ACACCAAAGT CCCTCGCAAT ACCAGGGCCC TTGTGGCTGG CGTCAGAAAC 
AGGCTGCTCA AGTTCCCAGA GATCGTGGCC CCCCTCCTGA CCTCAATAGA TGCCATCTCC 
CTGGAGTGTG AGCGCGTGCT GGGAGAGATG GGGGAAGCCC CAGCCCCGGA GCAGTACCTC 
GTGCTGGAAG AGCTCATTGA CATGAACCAG CACCATCTGA ATGCCCTCGG CGTGGGCCAC 
GCCTCTCTGG ACCAGCTCTG CCAGGTGACC AGGGCCCGCG GACTTCACAG CAAGCTGACT 
GGCGCAGGCG GTGGTGGCTG TGGCATCACA CTCCTCAAGC CAGGGCTGGA GCAGCCAGAA 
GTGGAGGCCA CGAAGCAGGC CCTGACCAGC TGTGGCTTTG ACTGCTTGGA AACCAGCATC 
GGTGCCCCCG GCGTCTCCAT CCACTCAGCC ACCTCCCTGG ACAGCCGAGT CCAGCAAGCC 
CTGGATGGCC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVK ( XM_017019313.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874802.1 Homo sapiens mevalonate kinase (MVK), transcript variant X2, mRNA.

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CloneID	OHu46565
Clone ID Related Accession (Same CDS sequence)	XM_017019313.2 , NM_001301182.1 , NM_001301182.2 , XM_017019313.1
Accession Version	XM_017019313.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	mevalonate kinase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017019313.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGTGGACCAA GGAGGATTTG GAGCTAATTA ACAAGTGGGC CTTCCAAGGG 
GAGAGAATGA TTCACGGGAA CCCCTCCGGA GTGGACAATG CTGTCAGCAC CTGGGGAGGA 
GCCCTCCGAT ACCATCAAGG GAAGATTTCA TCCTTAAAGA GGTCGCCAGC TCTCCAGATC 
CTGCTGACCA ACACCAAAGT CCCTCGCAAT ACCAGGGCCC TTGTGGCTGG CGTCAGAAAC 
AGGCTGCTCA AGTTCCCAGA GATCGTGGCC CCCCTCCTGA CCTCAATAGA TGCCATCTCC 
CTGGAGTGTG AGCGCGTGCT GGGAGAGATG GGGGAAGCCC CAGCCCCGGA GCAGTACCTC 
GTGCTGGAAG AGCTCATTGA CATGAACCAG CACCATCTGA ATGCCCTCGG CGTGGGCCAC 
GCCTCTCTGG ACCAGCTCTG CCAGGTGACC AGGGCCCGCG GACTTCACAG CAAGCTGACT 
GGCGCAGGCG GTGGTGGCTG TGGCATCACA CTCCTCAAGC CAGGGCTGGA GCAGCCAGAA 
GTGGAGGCCA CGAAGCAGGC CCTGACCAGC TGTGGCTTTG ACTGCTTGGA AACCAGCATC 
GGTGCCCCCG GCGTCTCCAT CCACTCAGCC ACCTCCCTGG ACAGCCGAGT CCAGCAAGCC 
CTGGATGGCC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874802.1
CDS	89..1123
Translation	MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

Target ORF information:

RefSeq Version	XM_017019313.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mevalonate kinase (MVK), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017019313.2

ORF Insert Sequence:

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGTGGACCAA GGAGGATTTG GAGCTAATTA ACAAGTGGGC CTTCCAAGGG 
GAGAGAATGA TTCACGGGAA CCCCTCCGGA GTGGACAATG CTGTCAGCAC CTGGGGAGGA 
GCCCTCCGAT ACCATCAAGG GAAGATTTCA TCCTTAAAGA GGTCGCCAGC TCTCCAGATC 
CTGCTGACCA ACACCAAAGT CCCTCGCAAT ACCAGGGCCC TTGTGGCTGG CGTCAGAAAC 
AGGCTGCTCA AGTTCCCAGA GATCGTGGCC CCCCTCCTGA CCTCAATAGA TGCCATCTCC 
CTGGAGTGTG AGCGCGTGCT GGGAGAGATG GGGGAAGCCC CAGCCCCGGA GCAGTACCTC 
GTGCTGGAAG AGCTCATTGA CATGAACCAG CACCATCTGA ATGCCCTCGG CGTGGGCCAC 
GCCTCTCTGG ACCAGCTCTG CCAGGTGACC AGGGCCCGCG GACTTCACAG CAAGCTGACT 
GGCGCAGGCG GTGGTGGCTG TGGCATCACA CTCCTCAAGC CAGGGCTGGA GCAGCCAGAA 
GTGGAGGCCA CGAAGCAGGC CCTGACCAGC TGTGGCTTTG ACTGCTTGGA AACCAGCATC 
GGTGCCCCCG GCGTCTCCAT CCACTCAGCC ACCTCCCTGG ACAGCCGAGT CCAGCAAGCC 
CTGGATGGCC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVK ( XM_017019313.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874802.1 Homo sapiens mevalonate kinase (MVK), transcript variant X2, mRNA.

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CloneID	OHu46565
Clone ID Related Accession (Same CDS sequence)	XM_017019313.2 , NM_001301182.1 , NM_001301182.2 , XM_017019313.1
Accession Version	XM_017019313.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	mevalonate kinase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGTGGACCAA GGAGGATTTG GAGCTAATTA ACAAGTGGGC CTTCCAAGGG 
GAGAGAATGA TTCACGGGAA CCCCTCCGGA GTGGACAATG CTGTCAGCAC CTGGGGAGGA 
GCCCTCCGAT ACCATCAAGG GAAGATTTCA TCCTTAAAGA GGTCGCCAGC TCTCCAGATC 
CTGCTGACCA ACACCAAAGT CCCTCGCAAT ACCAGGGCCC TTGTGGCTGG CGTCAGAAAC 
AGGCTGCTCA AGTTCCCAGA GATCGTGGCC CCCCTCCTGA CCTCAATAGA TGCCATCTCC 
CTGGAGTGTG AGCGCGTGCT GGGAGAGATG GGGGAAGCCC CAGCCCCGGA GCAGTACCTC 
GTGCTGGAAG AGCTCATTGA CATGAACCAG CACCATCTGA ATGCCCTCGG CGTGGGCCAC 
GCCTCTCTGG ACCAGCTCTG CCAGGTGACC AGGGCCCGCG GACTTCACAG CAAGCTGACT 
GGCGCAGGCG GTGGTGGCTG TGGCATCACA CTCCTCAAGC CAGGGCTGGA GCAGCCAGAA 
GTGGAGGCCA CGAAGCAGGC CCTGACCAGC TGTGGCTTTG ACTGCTTGGA AACCAGCATC 
GGTGCCCCCG GCGTCTCCAT CCACTCAGCC ACCTCCCTGG ACAGCCGAGT CCAGCAAGCC 
CTGGATGGCC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874802.1
CDS	147..1181
Translation	MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

Target ORF information:

RefSeq Version	XM_017019313.1
Organism	Homo sapiens(human)
Definition	Homo sapiens mevalonate kinase (MVK), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017019313.1

ORF Insert Sequence:

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGTGGACCAA GGAGGATTTG GAGCTAATTA ACAAGTGGGC CTTCCAAGGG 
GAGAGAATGA TTCACGGGAA CCCCTCCGGA GTGGACAATG CTGTCAGCAC CTGGGGAGGA 
GCCCTCCGAT ACCATCAAGG GAAGATTTCA TCCTTAAAGA GGTCGCCAGC TCTCCAGATC 
CTGCTGACCA ACACCAAAGT CCCTCGCAAT ACCAGGGCCC TTGTGGCTGG CGTCAGAAAC 
AGGCTGCTCA AGTTCCCAGA GATCGTGGCC CCCCTCCTGA CCTCAATAGA TGCCATCTCC 
CTGGAGTGTG AGCGCGTGCT GGGAGAGATG GGGGAAGCCC CAGCCCCGGA GCAGTACCTC 
GTGCTGGAAG AGCTCATTGA CATGAACCAG CACCATCTGA ATGCCCTCGG CGTGGGCCAC 
GCCTCTCTGG ACCAGCTCTG CCAGGTGACC AGGGCCCGCG GACTTCACAG CAAGCTGACT 
GGCGCAGGCG GTGGTGGCTG TGGCATCACA CTCCTCAAGC CAGGGCTGGA GCAGCCAGAA 
GTGGAGGCCA CGAAGCAGGC CCTGACCAGC TGTGGCTTTG ACTGCTTGGA AACCAGCATC 
GGTGCCCCCG GCGTCTCCAT CCACTCAGCC ACCTCCCTGG ACAGCCGAGT CCAGCAAGCC 
CTGGATGGCC TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVK ( XM_024448982.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024304750.1 Homo sapiens mevalonate kinase (MVK), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu103728
Clone ID Related Accession (Same CDS sequence)	XM_024448982.1
Accession Version	XM_024448982.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1170bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	mevalonate kinase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGTAAG AGCCTGTCTG 
CAGGAACCGG GGTTACTGAG TCCACACCAC TGTCCAAGGC AGTGGCTCTG CAATCTGGCT 
GTGCTCAGAA TCCCCCGGAA GCTAGCACAT AGAGGTCAGG ACCTGCCTCT GGCCTATGCT 
CTCAGCTGGG CCCAGGTCTG TGCGTGCCAT ATAAGCGTAT CTTATTTTCA GGCCTCTTCC 
TGGGTGATTC CGAGTAATTG GGAGAGTGCA AGGGAGGCCA GGGCCTGGCT CGTGCTAAGT 
GCAATGGAAA CAGGTTTGGG TCACTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024304750.1
CDS	126..1295
Translation	MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEVRACLQEPGLLSPHHCPRQWLCNLAVLRIPRKLAHRGQDLPLAYALSWAQVCACHISVSYFQASSWVIPSNWESAREARAWLVLSAMETGLGHF

Target ORF information:

RefSeq Version	XM_024448982.1
Organism	Homo sapiens(human)
Definition	Homo sapiens mevalonate kinase (MVK), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024448982.1

ORF Insert Sequence:

ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGTAAG AGCCTGTCTG 
CAGGAACCGG GGTTACTGAG TCCACACCAC TGTCCAAGGC AGTGGCTCTG CAATCTGGCT 
GTGCTCAGAA TCCCCCGGAA GCTAGCACAT AGAGGTCAGG ACCTGCCTCT GGCCTATGCT 
CTCAGCTGGG CCCAGGTCTG TGCGTGCCAT ATAAGCGTAT CTTATTTTCA GGCCTCTTCC 
TGGGTGATTC CGAGTAATTG GGAGAGTGCA AGGGAGGCCA GGGCCTGGCT CGTGCTAAGT 
GCAATGGAAA CAGGTTTGGG TCACTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MVK ( XM_011538372.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011536674.2 Homo sapiens mevalonate kinase (MVK), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu83787
Clone ID Related Accession (Same CDS sequence)	XM_011538372.2
Accession Version	XM_011538372.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1491bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	mevalonate kinase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011538372.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACGA CACCACGATT CACGGCAGGT GTTCGAGTTG CCCTTCCCGC CAGCCACTCA 
CCTGTCCCCG TCTTCCACGC CCTGAGGGCC GCGGCTCTGG AAACGGGGAT ACAGGAGCCT 
GGCGGCGCCG AAGCACCCGC GCAGGCCAAG ACGGCTCCCC AGGCCAAGAC GGCTCCCCAG 
GCCGCACACA GCCATGAGCC AGGCTGCTTG ACGGGACCTG ACCCCGCCAG GTTCCCGTCC 
AGTCCGCGGG GTGACTCCAC CCACAGCTGG CCGCGCCACC GCTCAGGATT CCCAGGAGCC 
ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011536674.2
CDS	2..1492
Translation	MATTPRFTAGVRVALPASHSPVPVFHALRAAALETGIQEPGGAEAPAQAKTAPQAKTAPQAAHSHEPGCLTGPDPARFPSSPRGDSTHSWPRHRSGFPGAMLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL

Target ORF information:

RefSeq Version	XM_011538372.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mevalonate kinase (MVK), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011538372.2

ORF Insert Sequence:

ATGGCGACGA CACCACGATT CACGGCAGGT GTTCGAGTTG CCCTTCCCGC CAGCCACTCA 
CCTGTCCCCG TCTTCCACGC CCTGAGGGCC GCGGCTCTGG AAACGGGGAT ACAGGAGCCT 
GGCGGCGCCG AAGCACCCGC GCAGGCCAAG ACGGCTCCCC AGGCCAAGAC GGCTCCCCAG 
GCCGCACACA GCCATGAGCC AGGCTGCTTG ACGGGACCTG ACCCCGCCAG GTTCCCGTCC 
AGTCCGCGGG GTGACTCCAC CCACAGCTGG CCGCGCCACC GCTCAGGATT CCCAGGAGCC 
ATGTTGTCAG AAGTCCTACT GGTGTCTGCT CCGGGGAAAG TCATCCTTCA TGGAGAACAT 
GCCGTGGTAC ATGGCAAGGT AGCACTGGCT GTATCCTTGA ACTTGAGAAC ATTCCTCCGG 
CTTCAACCCC ACAGCAATGG GAAAGTGGAC CTCAGCTTAC CCAACATTGG TATCAAGCGG 
GCCTGGGATG TGGCCAGGCT TCAGTCACTG GACACAAGCT TTCTGGAGCA AGGTGATGTC 
ACAACACCCA CCTCAGAGCA AGTGGAGAAG CTAAAGGAGG TTGCAGGCTT GCCTGACGAC 
TGTGCTGTCA CCGAGCGCCT GGCTGTGCTG GCCTTTCTTT ACTTATACCT GTCCATCTGC 
CGGAAGCAGA GGGCCCTGCC GAGCCTGGAT ATCGTAGTGT GGTCGGAGCT GCCCCCCGGG 
GCGGGCTTGG GCTCCAGCGC CGCCTACTCG GTGTGTCTGG CAGCAGCCCT CCTGACTGTG 
TGCGAGGAGA TCCCAAACCC GCTGAAGGAC GGGGATTGCG TCAACAGGTG GACCAAGGAG 
GATTTGGAGC TAATTAACAA GTGGGCCTTC CAAGGGGAGA GAATGATTCA CGGGAACCCC 
TCCGGAGTGG ACAATGCTGT CAGCACCTGG GGAGGAGCCC TCCGATACCA TCAAGGGAAG 
ATTTCATCCT TAAAGAGGTC GCCAGCTCTC CAGATCCTGC TGACCAACAC CAAAGTCCCT 
CGCAATACCA GGGCCCTTGT GGCTGGCGTC AGAAACAGGC TGCTCAAGTT CCCAGAGATC 
GTGGCCCCCC TCCTGACCTC AATAGATGCC ATCTCCCTGG AGTGTGAGCG CGTGCTGGGA 
GAGATGGGGG AAGCCCCAGC CCCGGAGCAG TACCTCGTGC TGGAAGAGCT CATTGACATG 
AACCAGCACC ATCTGAATGC CCTCGGCGTG GGCCACGCCT CTCTGGACCA GCTCTGCCAG 
GTGACCAGGG CCCGCGGACT TCACAGCAAG CTGACTGGCG CAGGCGGTGG TGGCTGTGGC 
ATCACACTCC TCAAGCCAGG GCTGGAGCAG CCAGAAGTGG AGGCCACGAA GCAGGCCCTG 
ACCAGCTGTG GCTTTGACTG CTTGGAAACC AGCATCGGTG CCCCCGGCGT CTCCATCCAC 
TCAGCCACCT CCCTGGACAG CCGAGTCCAG CAAGCCCTGG ATGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	MVK
Entrez Gene ID	4598
Full Name	mevalonate kinase
Synonyms	LRBP,MK,MVLK,POROK3
General protein information	Preferred Names mevalonate kinase Names mevalonate kinase LH receptor mRNA-binding protein mevalonate kinase 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q24.11
Summary	This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].
Disorder MIM:	251170
Disorder Html:	Mevalonic aciduria, 610377 (3); Hyper-IgD syndrome, 260920 (3); Porokeratosis 3, multiple types, 175900 (3)

	MVK	XP_001105815.1
Canis lupus familiaris (dog)	MVK	XP_005636378.1
Schizosaccharomyces pombe (fission yeast)	erg12	NP_592837.1
Homo sapiens (human)	MVK	NP_001107657.1
Pan troglodytes (chimpanzee)	MVK	XP_003313983.1
Magnaporthe oryzae (rice blast fungus)	MGG_16219	XP_003709688.1
Xenopus tropicalis (tropical clawed frog)	mvk	XP_002932110.2
Gallus gallus (chicken)	MVK	XP_001231562.3
Danio rerio (zebrafish)	mvk	NP_001007350.1
Neurospora crassa	NCU03633	XP_961360.1
Bos taurus (cattle)	MVK	NP_001015528.1
Mus musculus (house mouse)	Mvk	NP_076045.1
Rattus norvegicus (Norway rat)	Mvk	NP_112325.1
Kluyveromyces lactis	KLLA0C07469g	XP_452532.1
Eremothecium gossypii	AGOS_AER335W	NP_985191.1
Gallus gallus (chicken)	LOC100857437	XP_003643684.2
Caenorhabditis elegans (roundworm)	mvk-1	NP_001022869.1
Saccharomyces cerevisiae (baker's yeast)	ERG12	NP_013935.1
Arabidopsis thaliana (thale cress)	MK	NP_198097.1
Oryza sativa (rice)	Os10g0329300	NP_001064360.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

MVK cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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