TOPBP1 cDNA ORF clone, Pan troglodytes(chimpanzee)

Gene
Clones
gRNAs

Summary

Gene Symbol	TOPBP1
Entrez Gene ID	460709
Full Name	DNA topoisomerase II binding protein 1
General protein information	Preferred Names DNA topoisomerase II binding protein 1 Names DNA topoisomerase 2-binding protein 1 topoisomerase (DNA) II binding protein 1
Gene Type	protein-coding
Organism	Pan troglodytes(chimpanzee)

mRNA and Protein(s)

mRNA	Protein	Name
XM_009446507.2	XP_009444782.2	DNA topoisomerase 2-binding protein 1 isoform X3
XM_516761.7	XP_516761.5	DNA topoisomerase 2-binding protein 1 isoform X1
XM_516761.6	XP_516761.4	DNA topoisomerase 2-binding protein 1 isoform X1
XM_009446506.2	XP_009444781.2	DNA topoisomerase 2-binding protein 1 isoform X2
XM_009446506.3	XP_009444781.3	DNA topoisomerase 2-binding protein 1 isoform X2
XM_009446507.3	XP_009444782.3	DNA topoisomerase 2-binding protein 1 isoform X3

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TOPBP1	NP_001193695.1
Rattus norvegicus (Norway rat)	Topbp1	XP_236578.6
Homo sapiens (human)	TOPBP1	NP_008958.2
Danio rerio (zebrafish)	topbp1	NP_001186667.1
Xenopus tropicalis (tropical clawed frog)	topbp1	XP_004915426.1
	TOPBP1	XP_001112636.2
Mus musculus (house mouse)	Topbp1	NP_795953.2
Gallus gallus (chicken)	TOPBP1	XP_418794.1
Pan troglodytes (chimpanzee)	TOPBP1	XP_516761.3
Canis lupus familiaris (dog)	TOPBP1	XP_005634503.1

Gene Ontology

The following TOPBP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TOPBP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OPc38345	XM_009446507.3 Latest version!	Pan troglodytes DNA topoisomerase II binding protein 1 (TOPBP1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$713.30 $1019.00
OPc82706	XM_009446507.2 Latest version!	Pan troglodytes topoisomerase (DNA) II binding protein 1 (TOPBP1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$713.30 $1019.00
OPc07192	XM_516761.7 Latest version!	Pan troglodytes DNA topoisomerase II binding protein 1 (TOPBP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$881.30 $1259.00
OPc38344	XM_009446506.3 Latest version!	Pan troglodytes DNA topoisomerase II binding protein 1 (TOPBP1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$881.30 $1259.00
OPc82704	XM_516761.6 Latest version!	Pan troglodytes topoisomerase (DNA) II binding protein 1 (TOPBP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$881.30 $1259.00
OPc82705	XM_009446506.2 Latest version!	Pan troglodytes topoisomerase (DNA) II binding protein 1 (TOPBP1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$881.30 $1259.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TOPBP1 ( XM_009446507.3 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> XP_009444782.3 Pan troglodytes DNA topoisomerase II binding protein 1 (TOPBP1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OPc38345
Clone ID Related Accession (Same CDS sequence)	XM_009446507.3
Accession Version	XM_009446507.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3771bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-19
Organism	Pan troglodytes(chimpanzee)
Product	DNA topoisomerase 2-binding protein 1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_036882.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 20, 2018 this sequence version replaced XM_009446507.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Pan troglodytes Annotation Release 105 Annotation Version :: 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAGAA ATGACAAAGA ACCGTTTTTT GTGAAGTTTT TAAAGTCTTC AGACAATTCC 
AAATGTTTTT TTAAAGCTCT CGAGTCCATA AAAGAATTCC AATCAGAAGA ATATCTTCAG 
ATTATTACAG AAGAAGAGGC ATTGAAGATA AAGGAGAATG ATAGATCACT TTATATCTGT 
GACCCTTTTA GTGGCGTTGT CTTTGATCAC CTCAAAAAGC TTGGCTGCAG AATTGTTGGT 
CCTCAAGTAG TCATATTTTG TATGCACCAC CAGCGATGTG TCCCAAGAGC CGAACATCCA 
GTTTATAATA TGGTTATGTC TGATGTAACC ATATCTTGTA CAAGTCTGGA AAAAGAAAAA 
AGGGAAGAAG TTCATAAATA TGTACAAATG ATGGGCGGAC GAGTATACAG AGACCTTAAT 
GTATCAGTAA CTCACCTTAT TGCAGGAGAA GTTGGTAGCA AAAAATATTT AGTTGCTGCA 
AACCTGAAGA AACCTATTTT GCTTCCCTCT TGGATAAAAA CACTTTGGGA GAAGTCACAA 
GAGAAAAAAA TAACTAGATA TACTGATATA AACATGGAAG ATTTCAAGTG TCCTATTTTT 
CTTGGTTGCA TAATCTGTGT GACTGGCTTA TGTGGCTTAG ACAGGAAAGA AGTTCAGCAA 
CTCACAGTTA AGCATGGAGG TCAATACATG GGACAGTTGA AAATGAATGA ATGTACACAC 
CTCATTGTGC AAGAACCAAA AGGTCAGAAG TATGAGTGTG CCAAGAGATG GAATGTACAC 
TGTGTGACCA CACAGTGGTT TTTTGACAGT ATTGAGAAAG GTTTTTGTCA GGATGAATCC 
ATATACAAGA CAGAACCTAG ACCAGAAGCA AAGACTATGC CCAATTCTTC AACTCCTACC 
AGCCAGATCA ACACAATTGA TAGTCGTACT CTTTCAGATG TCAGCAATAT TTCCAACATA 
AATGCAAGTT GCGTAAGTGA ATCAATATGT AATTCACTTA ACAGCAAACT GGAGCCTACA 
CTTGAAAATC TAGAAAATCT GGATGTCAGT GCATTTCAAG CACCTGAAGA TTTATTAGAT 
GGTTGTCGGA TATATCTTTG CGGTTTTAGT GGCAGAAAGC TAGATAAACT GAGAAGACTT 
ATTAACAGTG GAGGTGGAGT TCGTTTTAAC CAGCTAAATG AAGATGTAAC TCATGTTATT 
GTGGGAGATT ATGATGATGA ATTGAAGCAG TTTTGGAATA AATCAGCCCA CAGGCCTCAT 
GTAGTGGGAG CAAAGTGGTT GCTAGAGTGT TTCAGTAAAG GTTATATGCT TTCTGAAGAA 
CCATATATCC ATGCTAATTA CCAGCCAGTG GAAATTCCAG TTTCACATCA GCCTGAAAGT 
AAAGCAGCTC TTTTAAAAAA GAAGAACAGC AGCTTCTCTA AGAAAGACTT TGCTCCTAGT 
GAAAAGCATG AGCAAGCTGA TGAAGATCTG CTCTCTCAAT ATGAAAATGA TAGCTCCACA 
GTAGTTGAGG CTAAGACGTC TGAAGCCAGG CCCTTTAATG ATTCTACTCA TGCTGAGCCC 
TTGAATGATT CTACTCACAT TTCTTTGCAA GAAGAAAACC AGTCTTCTGT CAGTCATTGT 
GTCCCTGATG TTTCTACAAT TACTGAAGAA GGCTTATTTA GCCAAAAGAG TTTCCTTGTT 
TTGGGTTTTA GTAATGAAAA TGAATCTAAC ATCGCAAACA TCATAAAAGA AAATGCTGGG 
AAAATCATGT CCCTTCTGAG CAGAACTGTT GCGGATTATG CTGTGGTTCC TCTGCTGGGG 
TGTGAAGTGG AAGCCACTGT GGGAGAAGTT GTTACAAATA CATGGCTGGT TACTTGCATA 
GACTATCAGA CTTTGTTTGA TCCAAAGTCG AATCCTCTCT TCACACCAGT CCCAGTAATG 
ACAGGAATGA CTCCTTTAGA GGATTGTGTT ATTTCATTTA GCCAGTGTGC TGGAGCAGAA 
AAAGAGTCTT TAACATTCCT AGCAAACCTC CTTGGAGCAA GTGTTCAAGA ATACTTTGTT 
CGCAAATCCA ATGCAAAGAA AGGCATGTTT GCCAGTACTC ATCTTATACT GAAAGAACGT 
GGTGGCTCTA AATATGAAGC TGCAAAGAAG TGGAATTTAC CTGCAGTTAC TATAGCTTGG 
CTGTTGGAGA CTGCTAGAAC GGGAAAGAGA GCAGACGAAA GCCATTTTCT GATTGAAAAT 
TCATCTAAAG AAGAACGAAG TTTGGAAACA GAAATAACAA ATGGAATCAA TCTAAATTCA 
GATACTGCAG AGCATCCTGG CACACGCCTG CAAACTCACA GAAAAACCGT CGTTACACCT 
TTAGATATGA ACCGCTTTCA GAGTAAAGCT TTCCGTGCTG TGGTCTCACA ACATGCCAGA 
CAGGTCGCAG CCTCCCCAGC AGTAGGACAA CCACTTCAGA AGGAGCCCTC GTTACACCTG 
GATACACCAT CAAAATTCCT GTCCAAGGAC AAACTCTTCA AGCCTTCCTT TGATGTGAAG 
GATGCACTTG CAGCCTTGGA AACTCCAGGA CGTCCCAGCC AACAGAAAAG GAAACTGAGT 
ACGCCACTCT CAGAAGTTAT TGTCAAAAAC TTGCAACTTG CTTTGGCAAA TAGCTCTCGA 
AATGCTGTCG CTCTTTCTGC CAGCCCTCAG CTGAAAGAGG CCCAGTCAGA GAAGGAAGAA 
GCCCCAAAGC CACTTCACAA AGTAGTGGTA TGTGTTAGTA AAAAACTCGG TAAAAAGCAG 
AGTGAACTAA ATGGGATCGC AGCCTCTCTA GGAGCAGATT ACAGGTGGAG TTTTGATGAA 
ACAGTGACTC ATTTCATCTA TCAAGGGCGG CCAAATGACA CTAATCGGGA GTATAAATCT 
GTAAAAGAAA GAGGAGTACA CATTGTTTCC GAGCACTGGC TTTTAGATTG TGCCCAAGAG 
TGTAAACATC TTCCTGAATC TCTTTATCCG CATACTTATA ATCCCAAAAT GAGCTTGGAT 
ATCAGTGCAG TGCAAGATGG CCGACTCTGT AATAGTCGAC TACTCTCAGC TGTGTCTGCA 
ACAAAGGATG ATGAGCCAGA TCCTTTGATT TTAGAAGAAA ATGATGTAGA CAATATGGCC 
ACCAATAATA AAGAGTCAGC ACCATCAAAT GGAAGTGGAA AGAATGACTC TAAAGGAGTT 
CTGACACAGA CCTTAGAGAT GAGAGAGAAC TTTCAGAAGC AGTTACAGGA GATAATGTCT 
GCAACATCAA TAGTGAAACC CCAAGGGCAG AGGACTTCCC TTTCAAGAAG TGGTTGTAAC 
AGCGCATCTT CAACCCCTGA CAGCAGTCGC TCTGCTCGCA GTGGACGAAG TAGAGTCCTA 
GAGGCACTGA GGCAGTCTCG TCAAACAGTA CCTGATGTCA ACACAGAGCC TTCCCAAAAT 
GAACAGATTA TTTGGGATGA CCCTACAGCA AGGGAGGAGA GAGCAAGGCT TGCCAGCAAT 
TTGCAGTGGC CTAGTTGTCC CACACAATAC TCTGAGCTTC AGGTTGACAT TCAAAACTTG 
GAGGATTCTC CTTTTCAAAA GCCTTTACAT GATTCAGAAA TTGCTAAACA GGCTGTCTGT 
GATCCTGGAA ACATACGTGT GACTGAAGCT CCCAAACACC CAATCTCTGA AGAACTGGAA 
ACTCCCATAA AAGATAGCCA CCTGATCCCT ACGCCTCAAG CCCCCAGTAT TGCCTTTCCA 
CTCGCCAACC CCCCTGTGGC TCCGCACCCT AGAGAAAAGG TGGATTGGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_009444782.3
CDS	159..3929
Translation	MSRNDKEPFFVKFLKSSDNSKCFFKALESIKEFQSEEYLQIITEEEALKIKENDRSLYICDPFSGVVFDHLKKLGCRIVGPQVVIFCMHHQRCVPRAEHPVYNMVMSDVTISCTSLEKEKREEVHKYVQMMGGRVYRDLNVSVTHLIAGEVGSKKYLVAANLKKPILLPSWIKTLWEKSQEKKITRYTDINMEDFKCPIFLGCIICVTGLCGLDRKEVQQLTVKHGGQYMGQLKMNECTHLIVQEPKGQKYECAKRWNVHCVTTQWFFDSIEKGFCQDESIYKTEPRPEAKTMPNSSTPTSQINTIDSRTLSDVSNISNINASCVSESICNSLNSKLEPTLENLENLDVSAFQAPEDLLDGCRIYLCGFSGRKLDKLRRLINSGGGVRFNQLNEDVTHVIVGDYDDELKQFWNKSAHRPHVVGAKWLLECFSKGYMLSEEPYIHANYQPVEIPVSHQPESKAALLKKKNSSFSKKDFAPSEKHEQADEDLLSQYENDSSTVVEAKTSEARPFNDSTHAEPLNDSTHISLQEENQSSVSHCVPDVSTITEEGLFSQKSFLVLGFSNENESNIANIIKENAGKIMSLLSRTVADYAVVPLLGCEVEATVGEVVTNTWLVTCIDYQTLFDPKSNPLFTPVPVMTGMTPLEDCVISFSQCAGAEKESLTFLANLLGASVQEYFVRKSNAKKGMFASTHLILKERGGSKYEAAKKWNLPAVTIAWLLETARTGKRADESHFLIENSSKEERSLETEITNGINLNSDTAEHPGTRLQTHRKTVVTPLDMNRFQSKAFRAVVSQHARQVAASPAVGQPLQKEPSLHLDTPSKFLSKDKLFKPSFDVKDALAALETPGRPSQQKRKLSTPLSEVIVKNLQLALANSSRNAVALSASPQLKEAQSEKEEAPKPLHKVVVCVSKKLGKKQSELNGIAASLGADYRWSFDETVTHFIYQGRPNDTNREYKSVKERGVHIVSEHWLLDCAQECKHLPESLYPHTYNPKMSLDISAVQDGRLCNSRLLSAVSATKDDEPDPLILEENDVDNMATNNKESAPSNGSGKNDSKGVLTQTLEMRENFQKQLQEIMSATSIVKPQGQRTSLSRSGCNSASSTPDSSRSARSGRSRVLEALRQSRQTVPDVNTEPSQNEQIIWDDPTAREERARLASNLQWPSCPTQYSELQVDIQNLEDSPFQKPLHDSEIAKQAVCDPGNIRVTEAPKHPISEELETPIKDSHLIPTPQAPSIAFPLANPPVAPHPREKVDW

Target ORF information:

RefSeq Version	XM_009446507.3
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes DNA topoisomerase II binding protein 1 (TOPBP1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_009446507.3

ORF Insert Sequence:

ATGTCCAGAA ATGACAAAGA ACCGTTTTTT GTGAAGTTTT TAAAGTCTTC AGACAATTCC 
AAATGTTTTT TTAAAGCTCT CGAGTCCATA AAAGAATTCC AATCAGAAGA ATATCTTCAG 
ATTATTACAG AAGAAGAGGC ATTGAAGATA AAGGAGAATG ATAGATCACT TTATATCTGT 
GACCCTTTTA GTGGCGTTGT CTTTGATCAC CTCAAAAAGC TTGGCTGCAG AATTGTTGGT 
CCTCAAGTAG TCATATTTTG TATGCACCAC CAGCGATGTG TCCCAAGAGC CGAACATCCA 
GTTTATAATA TGGTTATGTC TGATGTAACC ATATCTTGTA CAAGTCTGGA AAAAGAAAAA 
AGGGAAGAAG TTCATAAATA TGTACAAATG ATGGGCGGAC GAGTATACAG AGACCTTAAT 
GTATCAGTAA CTCACCTTAT TGCAGGAGAA GTTGGTAGCA AAAAATATTT AGTTGCTGCA 
AACCTGAAGA AACCTATTTT GCTTCCCTCT TGGATAAAAA CACTTTGGGA GAAGTCACAA 
GAGAAAAAAA TAACTAGATA TACTGATATA AACATGGAAG ATTTCAAGTG TCCTATTTTT 
CTTGGTTGCA TAATCTGTGT GACTGGCTTA TGTGGCTTAG ACAGGAAAGA AGTTCAGCAA 
CTCACAGTTA AGCATGGAGG TCAATACATG GGACAGTTGA AAATGAATGA ATGTACACAC 
CTCATTGTGC AAGAACCAAA AGGTCAGAAG TATGAGTGTG CCAAGAGATG GAATGTACAC 
TGTGTGACCA CACAGTGGTT TTTTGACAGT ATTGAGAAAG GTTTTTGTCA GGATGAATCC 
ATATACAAGA CAGAACCTAG ACCAGAAGCA AAGACTATGC CCAATTCTTC AACTCCTACC 
AGCCAGATCA ACACAATTGA TAGTCGTACT CTTTCAGATG TCAGCAATAT TTCCAACATA 
AATGCAAGTT GCGTAAGTGA ATCAATATGT AATTCACTTA ACAGCAAACT GGAGCCTACA 
CTTGAAAATC TAGAAAATCT GGATGTCAGT GCATTTCAAG CACCTGAAGA TTTATTAGAT 
GGTTGTCGGA TATATCTTTG CGGTTTTAGT GGCAGAAAGC TAGATAAACT GAGAAGACTT 
ATTAACAGTG GAGGTGGAGT TCGTTTTAAC CAGCTAAATG AAGATGTAAC TCATGTTATT 
GTGGGAGATT ATGATGATGA ATTGAAGCAG TTTTGGAATA AATCAGCCCA CAGGCCTCAT 
GTAGTGGGAG CAAAGTGGTT GCTAGAGTGT TTCAGTAAAG GTTATATGCT TTCTGAAGAA 
CCATATATCC ATGCTAATTA CCAGCCAGTG GAAATTCCAG TTTCACATCA GCCTGAAAGT 
AAAGCAGCTC TTTTAAAAAA GAAGAACAGC AGCTTCTCTA AGAAAGACTT TGCTCCTAGT 
GAAAAGCATG AGCAAGCTGA TGAAGATCTG CTCTCTCAAT ATGAAAATGA TAGCTCCACA 
GTAGTTGAGG CTAAGACGTC TGAAGCCAGG CCCTTTAATG ATTCTACTCA TGCTGAGCCC 
TTGAATGATT CTACTCACAT TTCTTTGCAA GAAGAAAACC AGTCTTCTGT CAGTCATTGT 
GTCCCTGATG TTTCTACAAT TACTGAAGAA GGCTTATTTA GCCAAAAGAG TTTCCTTGTT 
TTGGGTTTTA GTAATGAAAA TGAATCTAAC ATCGCAAACA TCATAAAAGA AAATGCTGGG 
AAAATCATGT CCCTTCTGAG CAGAACTGTT GCGGATTATG CTGTGGTTCC TCTGCTGGGG 
TGTGAAGTGG AAGCCACTGT GGGAGAAGTT GTTACAAATA CATGGCTGGT TACTTGCATA 
GACTATCAGA CTTTGTTTGA TCCAAAGTCG AATCCTCTCT TCACACCAGT CCCAGTAATG 
ACAGGAATGA CTCCTTTAGA GGATTGTGTT ATTTCATTTA GCCAGTGTGC TGGAGCAGAA 
AAAGAGTCTT TAACATTCCT AGCAAACCTC CTTGGAGCAA GTGTTCAAGA ATACTTTGTT 
CGCAAATCCA ATGCAAAGAA AGGCATGTTT GCCAGTACTC ATCTTATACT GAAAGAACGT 
GGTGGCTCTA AATATGAAGC TGCAAAGAAG TGGAATTTAC CTGCAGTTAC TATAGCTTGG 
CTGTTGGAGA CTGCTAGAAC GGGAAAGAGA GCAGACGAAA GCCATTTTCT GATTGAAAAT 
TCATCTAAAG AAGAACGAAG TTTGGAAACA GAAATAACAA ATGGAATCAA TCTAAATTCA 
GATACTGCAG AGCATCCTGG CACACGCCTG CAAACTCACA GAAAAACCGT CGTTACACCT 
TTAGATATGA ACCGCTTTCA GAGTAAAGCT TTCCGTGCTG TGGTCTCACA ACATGCCAGA 
CAGGTCGCAG CCTCCCCAGC AGTAGGACAA CCACTTCAGA AGGAGCCCTC GTTACACCTG 
GATACACCAT CAAAATTCCT GTCCAAGGAC AAACTCTTCA AGCCTTCCTT TGATGTGAAG 
GATGCACTTG CAGCCTTGGA AACTCCAGGA CGTCCCAGCC AACAGAAAAG GAAACTGAGT 
ACGCCACTCT CAGAAGTTAT TGTCAAAAAC TTGCAACTTG CTTTGGCAAA TAGCTCTCGA 
AATGCTGTCG CTCTTTCTGC CAGCCCTCAG CTGAAAGAGG CCCAGTCAGA GAAGGAAGAA 
GCCCCAAAGC CACTTCACAA AGTAGTGGTA TGTGTTAGTA AAAAACTCGG TAAAAAGCAG 
AGTGAACTAA ATGGGATCGC AGCCTCTCTA GGAGCAGATT ACAGGTGGAG TTTTGATGAA 
ACAGTGACTC ATTTCATCTA TCAAGGGCGG CCAAATGACA CTAATCGGGA GTATAAATCT 
GTAAAAGAAA GAGGAGTACA CATTGTTTCC GAGCACTGGC TTTTAGATTG TGCCCAAGAG 
TGTAAACATC TTCCTGAATC TCTTTATCCG CATACTTATA ATCCCAAAAT GAGCTTGGAT 
ATCAGTGCAG TGCAAGATGG CCGACTCTGT AATAGTCGAC TACTCTCAGC TGTGTCTGCA 
ACAAAGGATG ATGAGCCAGA TCCTTTGATT TTAGAAGAAA ATGATGTAGA CAATATGGCC 
ACCAATAATA AAGAGTCAGC ACCATCAAAT GGAAGTGGAA AGAATGACTC TAAAGGAGTT 
CTGACACAGA CCTTAGAGAT GAGAGAGAAC TTTCAGAAGC AGTTACAGGA GATAATGTCT 
GCAACATCAA TAGTGAAACC CCAAGGGCAG AGGACTTCCC TTTCAAGAAG TGGTTGTAAC 
AGCGCATCTT CAACCCCTGA CAGCAGTCGC TCTGCTCGCA GTGGACGAAG TAGAGTCCTA 
GAGGCACTGA GGCAGTCTCG TCAAACAGTA CCTGATGTCA ACACAGAGCC TTCCCAAAAT 
GAACAGATTA TTTGGGATGA CCCTACAGCA AGGGAGGAGA GAGCAAGGCT TGCCAGCAAT 
TTGCAGTGGC CTAGTTGTCC CACACAATAC TCTGAGCTTC AGGTTGACAT TCAAAACTTG 
GAGGATTCTC CTTTTCAAAA GCCTTTACAT GATTCAGAAA TTGCTAAACA GGCTGTCTGT 
GATCCTGGAA ACATACGTGT GACTGAAGCT CCCAAACACC CAATCTCTGA AGAACTGGAA 
ACTCCCATAA AAGATAGCCA CCTGATCCCT ACGCCTCAAG CCCCCAGTAT TGCCTTTCCA 
CTCGCCAACC CCCCTGTGGC TCCGCACCCT AGAGAAAAGG TGGATTGGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOPBP1 ( XM_009446507.2 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> XP_009444782.2 Pan troglodytes topoisomerase (DNA) II binding protein 1 (TOPBP1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OPc82706
Clone ID Related Accession (Same CDS sequence)	XM_009446507.2
Accession Version	XM_009446507.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3771bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-01
Organism	Pan troglodytes(chimpanzee)
Product	DNA topoisomerase 2-binding protein 1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006490.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 2, 2016 this sequence version replaced XM_009446507.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Pan troglodytes Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAGAA ATGACAAAGA ACCGTTTTTT GTGAAGTTTT TAAAGTCTTC AGACAATTCC 
AAATGTTTTT TTAAAGCTCT CGAGTCCATA AAAGAATTCC AATCAGAAGA ATATCTTCAG 
ATTATTACAG AAGAAGAGGC ATTGAAGATA AAGGAGAATG ATAGATCACT TTATATCTGT 
GACCCTTTTA GTGGCGTTGT CTTTGATCAC CTCAAAAAGC TTGGCTGCAG AATTGTTGGT 
CCTCAAGTAG TCATATTTTG TATGCACCAC CAGCGATGTG TCCCAAGAGC CGAACATCCA 
GTTTATAATA TGGTTATGTC TGATGTAACC ATATCTTGTA CAAGTCTGGA AAAAGAAAAA 
AGGGAAGAAG TTCATAAATA TGTACAAATG ATGGGCGGAC GAGTATACAG AGACCTTAAT 
GTATCAGTAA CTCACCTTAT TGCAGGAGAA GTTGGTAGCA AAAAATATTT AGTTGCTGCA 
AACCTGAAGA AACCTATTTT GCTTCCCTCT TGGATAAAAA CACTTTGGGA GAAGTCACAA 
GAGAAAAAAA TAACTAGATA TACTGATATA AACATGGAAG ATTTCAAGTG TCCTATTTTT 
CTTGGTTGCA TAATCTGTGT GACTGGCTTA TGTGGCTTAG ACAGGAAAGA AGTTCAGCAA 
CTCACAGTTA AGCATGGAGG TCAATACATG GGACAGTTGA AAATGAATGA ATGTACACAC 
CTCATTGTGC AAGAACCAAA AGGTCAGAAG TATGAGTGTG CCAAGAGATG GAATGTACAC 
TGTGTGACCA CACAGTGGTT TTTTGACAGT ATTGAGAAAG GTTTTTGTCA GGATGAATCC 
ATATACAAGA CAGAACCTAG ACCAGAAGCA AAGACTATGC CCAATTCTTC AACTCCTACC 
AGCCAGATCA ACACAATTGA TAGTCGTACT CTTTCAGATG TCAGCAATAT TTCCAACATA 
AATGCAAGTT GCGTAAGTGA ATCAATATGT AATTCACTTA ACAGCAAACT GGAGCCTACA 
CTTGAAAATC TAGAAAATCT GGATGTCAGT GCATTTCAAG CACCTGAAGA TTTATTAGAT 
GGTTGTCGGA TATATCTTTG CGGTTTTAGT GGCAGAAAGC TAGATAAACT GAGAAGACTT 
ATTAACAGTG GAGGTGGAGT TCGTTTTAAC CAGCTAAATG AAGATGTAAC TCATGTTATT 
GTGGGAGATT ATGATGATGA ATTGAAGCAG TTTTGGAATA AATCAGCCCA CAGGCCTCAT 
GTAGTGGGAG CAAAGTGGTT GCTAGAGTGT TTCAGTAAAG GTTATATGCT TTCTGAAGAA 
CCATATATCC ATGCTAATTA CCAGCCAGTG GAAATTCCAG TTTCACATCA GCCTGAAAGT 
AAAGCAGCTC TTTTAAAAAA GAAGAACAGC AGCTTCTCTA AGAAAGACTT TGCTCCTAGT 
GAAAAGCATG AGCAAGCTGA TGAAGATCTG CTCTCTCAAT ATGAAAATGA TAGCTCCACA 
GTAGTTGAGG CTAAGACGTC TGAAGCCAGG CCCTTTAATG ATTCTACTCA TGCTGAGCCC 
TTGAATGATT CTACTCACAT TTCTTTGCAA GAAGAAAACC AGTCTTCTGT CAGTCATTGT 
GTCCCTGATG TTTCTACAAT TACTGAAGAA GGCTTATTTA GCCAAAAGAG TTTCCTTGTT 
TTGGGTTTTA GTAATGAAAA TGAATCTAAC ATCGCAAACA TCATAAAAGA AAATGCTGGG 
AAAATCATGT CCCTTCTGAG CAGAACTGTT GCGGATTATG CTGTGGTTCC TCTGCTGGGG 
TGTGAAGTGG AAGCCACTGT GGGAGAAGTT GTTACAAATA CATGGCTGGT TACTTGCATA 
GACTATCAGA CTTTGTTTGA TCCAAAGTCG AATCCTCTCT TCACACCAGT CCCAGTAATG 
ACAGGAATGA CTCCTTTAGA GGATTGTGTT ATTTCATTTA GCCAGTGTGC TGGAGCAGAA 
AAAGAGTCTT TAACATTCCT AGCAAACCTC CTTGGAGCAA GTGTTCAAGA ATACTTTGTT 
CGCAAATCCA ATGCAAAGAA AGGCATGTTT GCCAGTACTC ATCTTATACT GAAAGAACGT 
GGTGGCTCTA AATATGAAGC TGCAAAGAAG TGGAATTTAC CTGCAGTTAC TATAGCTTGG 
CTGTTGGAGA CTGCTAGAAC GGGAAAGAGA GCAGACGAAA GCCATTTTCT GATTGAAAAT 
TCATCTAAAG AAGAACGAAG TTTGGAAACA GAAATAACAA ATGGAATCAA TCTAAATTCA 
GATACTGCAG AGCATCCTGG CACACGCCTG CAAACTCACA GAAAAACCGT CGTTACACCT 
TTAGATATGA ACCGCTTTCA GAGTAAAGCT TTCCGTGCTG TGGTCTCACA ACATGCCAGA 
CAGGTCGCAG CCTCCCCAGC AGTAGGACAA CCACTTCAGA AGGAGCCCTC GTTACACCTG 
GATACACCAT CAAAATTCCT GTCCAAGGAC AAACTCTTCA AGCCTTCCTT TGATGTGAAG 
GATGCACTTG CAGCCTTGGA AACTCCAGGA CGTCCCAGCC AACAGAAAAG GAAACTGAGT 
ACGCCACTCT CAGAAGTTAT TGTCAAAAAC TTGCAACTTG CTTTGGCAAA TAGCTCTCGA 
AATGCTGTCG CTCTTTCTGC CAGCCCTCAG CTGAAAGAGG CCCAGTCAGA GAAGGAAGAA 
GCCCCAAAGC CACTTCACAA AGTAGTGGTA TGTGTTAGTA AAAAACTCGG TAAAAAGCAG 
AGTGAACTAA ATGGGATCGC AGCCTCTCTA GGAGCAGATT ACAGGTGGAG TTTTGATGAA 
ACAGTGACTC ATTTCATCTA TCAAGGGCGG CCAAATGACA CTAATCGGGA GTATAAATCT 
GTAAAAGAAA GAGGAGTACA CATTGTTTCC GAGCACTGGC TTTTAGATTG TGCCCAAGAG 
TGTAAACATC TTCCTGAATC TCTTTATCCG CATACTTATA ATCCCAAAAT GAGCTTGGAT 
ATCAGTGCAG TGCAAGATGG CCGACTCTGT AATAGTCGAC TACTCTCAGC TGTGTCTGCA 
ACAAAGGATG ATGAGCCAGA TCCTTTGATT TTAGAAGAAA ATGATGTAGA CAATATGGCC 
ACCAATAATA AAGAGTCAGC ACCATCAAAT GGAAGTGGAA AGAATGACTC TAAAGGAGTT 
CTGACACAGA CCTTAGAGAT GAGAGAGAAC TTTCAGAAGC AGTTACAGGA GATAATGTCT 
GCAACATCAA TAGTGAAACC CCAAGGGCAG AGGACTTCCC TTTCAAGAAG TGGTTGTAAC 
AGCGCATCTT CAACCCCTGA CAGCACTCGC TCTGCTCGCA GTGGACGAAG TAGAGTCCTA 
GAGGCACTGA GGCAGTCTCG TCAAACAGTA CCTGATGTCA ACACAGAGCC TTCCCAAAAT 
GAACAGATTA TTTGGGATGA CCCTACAGCA AGGGAGGAGA GAGCAAGGCT TGCCAGCAAT 
TTGCAGTGGC CTAGTTGTCC CACACAATAC TCTGAGCTTC AGGTTGACAT TCAAAACTTG 
GAGGATTCTC CTTTTCAAAA GCCTTTACAT GATTCAGAAA TTGCTAAACA GGCTGTCTGT 
GATCCTGGAA ACATACGTGT GACTGAAGCT CCCAAACACC CAATCTCTGA AGAACTGGAA 
ACTCCCATAA AAGATAGCCA CCTGATCCCT ACGCCTCAAG CCCCCAGTAT TGCCTTTCCA 
CTCGCCAACC CCCCTGTGGC TCCGCACCCT AGAGAAAAGG TGGATTGGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_009444782.2
CDS	159..3929
Translation	MSRNDKEPFFVKFLKSSDNSKCFFKALESIKEFQSEEYLQIITEEEALKIKENDRSLYICDPFSGVVFDHLKKLGCRIVGPQVVIFCMHHQRCVPRAEHPVYNMVMSDVTISCTSLEKEKREEVHKYVQMMGGRVYRDLNVSVTHLIAGEVGSKKYLVAANLKKPILLPSWIKTLWEKSQEKKITRYTDINMEDFKCPIFLGCIICVTGLCGLDRKEVQQLTVKHGGQYMGQLKMNECTHLIVQEPKGQKYECAKRWNVHCVTTQWFFDSIEKGFCQDESIYKTEPRPEAKTMPNSSTPTSQINTIDSRTLSDVSNISNINASCVSESICNSLNSKLEPTLENLENLDVSAFQAPEDLLDGCRIYLCGFSGRKLDKLRRLINSGGGVRFNQLNEDVTHVIVGDYDDELKQFWNKSAHRPHVVGAKWLLECFSKGYMLSEEPYIHANYQPVEIPVSHQPESKAALLKKKNSSFSKKDFAPSEKHEQADEDLLSQYENDSSTVVEAKTSEARPFNDSTHAEPLNDSTHISLQEENQSSVSHCVPDVSTITEEGLFSQKSFLVLGFSNENESNIANIIKENAGKIMSLLSRTVADYAVVPLLGCEVEATVGEVVTNTWLVTCIDYQTLFDPKSNPLFTPVPVMTGMTPLEDCVISFSQCAGAEKESLTFLANLLGASVQEYFVRKSNAKKGMFASTHLILKERGGSKYEAAKKWNLPAVTIAWLLETARTGKRADESHFLIENSSKEERSLETEITNGINLNSDTAEHPGTRLQTHRKTVVTPLDMNRFQSKAFRAVVSQHARQVAASPAVGQPLQKEPSLHLDTPSKFLSKDKLFKPSFDVKDALAALETPGRPSQQKRKLSTPLSEVIVKNLQLALANSSRNAVALSASPQLKEAQSEKEEAPKPLHKVVVCVSKKLGKKQSELNGIAASLGADYRWSFDETVTHFIYQGRPNDTNREYKSVKERGVHIVSEHWLLDCAQECKHLPESLYPHTYNPKMSLDISAVQDGRLCNSRLLSAVSATKDDEPDPLILEENDVDNMATNNKESAPSNGSGKNDSKGVLTQTLEMRENFQKQLQEIMSATSIVKPQGQRTSLSRSGCNSASSTPDSTRSARSGRSRVLEALRQSRQTVPDVNTEPSQNEQIIWDDPTAREERARLASNLQWPSCPTQYSELQVDIQNLEDSPFQKPLHDSEIAKQAVCDPGNIRVTEAPKHPISEELETPIKDSHLIPTPQAPSIAFPLANPPVAPHPREKVDW

Target ORF information:

RefSeq Version	XM_009446507.2
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes topoisomerase (DNA) II binding protein 1 (TOPBP1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_009446507.2

ORF Insert Sequence:

ATGTCCAGAA ATGACAAAGA ACCGTTTTTT GTGAAGTTTT TAAAGTCTTC AGACAATTCC 
AAATGTTTTT TTAAAGCTCT CGAGTCCATA AAAGAATTCC AATCAGAAGA ATATCTTCAG 
ATTATTACAG AAGAAGAGGC ATTGAAGATA AAGGAGAATG ATAGATCACT TTATATCTGT 
GACCCTTTTA GTGGCGTTGT CTTTGATCAC CTCAAAAAGC TTGGCTGCAG AATTGTTGGT 
CCTCAAGTAG TCATATTTTG TATGCACCAC CAGCGATGTG TCCCAAGAGC CGAACATCCA 
GTTTATAATA TGGTTATGTC TGATGTAACC ATATCTTGTA CAAGTCTGGA AAAAGAAAAA 
AGGGAAGAAG TTCATAAATA TGTACAAATG ATGGGCGGAC GAGTATACAG AGACCTTAAT 
GTATCAGTAA CTCACCTTAT TGCAGGAGAA GTTGGTAGCA AAAAATATTT AGTTGCTGCA 
AACCTGAAGA AACCTATTTT GCTTCCCTCT TGGATAAAAA CACTTTGGGA GAAGTCACAA 
GAGAAAAAAA TAACTAGATA TACTGATATA AACATGGAAG ATTTCAAGTG TCCTATTTTT 
CTTGGTTGCA TAATCTGTGT GACTGGCTTA TGTGGCTTAG ACAGGAAAGA AGTTCAGCAA 
CTCACAGTTA AGCATGGAGG TCAATACATG GGACAGTTGA AAATGAATGA ATGTACACAC 
CTCATTGTGC AAGAACCAAA AGGTCAGAAG TATGAGTGTG CCAAGAGATG GAATGTACAC 
TGTGTGACCA CACAGTGGTT TTTTGACAGT ATTGAGAAAG GTTTTTGTCA GGATGAATCC 
ATATACAAGA CAGAACCTAG ACCAGAAGCA AAGACTATGC CCAATTCTTC AACTCCTACC 
AGCCAGATCA ACACAATTGA TAGTCGTACT CTTTCAGATG TCAGCAATAT TTCCAACATA 
AATGCAAGTT GCGTAAGTGA ATCAATATGT AATTCACTTA ACAGCAAACT GGAGCCTACA 
CTTGAAAATC TAGAAAATCT GGATGTCAGT GCATTTCAAG CACCTGAAGA TTTATTAGAT 
GGTTGTCGGA TATATCTTTG CGGTTTTAGT GGCAGAAAGC TAGATAAACT GAGAAGACTT 
ATTAACAGTG GAGGTGGAGT TCGTTTTAAC CAGCTAAATG AAGATGTAAC TCATGTTATT 
GTGGGAGATT ATGATGATGA ATTGAAGCAG TTTTGGAATA AATCAGCCCA CAGGCCTCAT 
GTAGTGGGAG CAAAGTGGTT GCTAGAGTGT TTCAGTAAAG GTTATATGCT TTCTGAAGAA 
CCATATATCC ATGCTAATTA CCAGCCAGTG GAAATTCCAG TTTCACATCA GCCTGAAAGT 
AAAGCAGCTC TTTTAAAAAA GAAGAACAGC AGCTTCTCTA AGAAAGACTT TGCTCCTAGT 
GAAAAGCATG AGCAAGCTGA TGAAGATCTG CTCTCTCAAT ATGAAAATGA TAGCTCCACA 
GTAGTTGAGG CTAAGACGTC TGAAGCCAGG CCCTTTAATG ATTCTACTCA TGCTGAGCCC 
TTGAATGATT CTACTCACAT TTCTTTGCAA GAAGAAAACC AGTCTTCTGT CAGTCATTGT 
GTCCCTGATG TTTCTACAAT TACTGAAGAA GGCTTATTTA GCCAAAAGAG TTTCCTTGTT 
TTGGGTTTTA GTAATGAAAA TGAATCTAAC ATCGCAAACA TCATAAAAGA AAATGCTGGG 
AAAATCATGT CCCTTCTGAG CAGAACTGTT GCGGATTATG CTGTGGTTCC TCTGCTGGGG 
TGTGAAGTGG AAGCCACTGT GGGAGAAGTT GTTACAAATA CATGGCTGGT TACTTGCATA 
GACTATCAGA CTTTGTTTGA TCCAAAGTCG AATCCTCTCT TCACACCAGT CCCAGTAATG 
ACAGGAATGA CTCCTTTAGA GGATTGTGTT ATTTCATTTA GCCAGTGTGC TGGAGCAGAA 
AAAGAGTCTT TAACATTCCT AGCAAACCTC CTTGGAGCAA GTGTTCAAGA ATACTTTGTT 
CGCAAATCCA ATGCAAAGAA AGGCATGTTT GCCAGTACTC ATCTTATACT GAAAGAACGT 
GGTGGCTCTA AATATGAAGC TGCAAAGAAG TGGAATTTAC CTGCAGTTAC TATAGCTTGG 
CTGTTGGAGA CTGCTAGAAC GGGAAAGAGA GCAGACGAAA GCCATTTTCT GATTGAAAAT 
TCATCTAAAG AAGAACGAAG TTTGGAAACA GAAATAACAA ATGGAATCAA TCTAAATTCA 
GATACTGCAG AGCATCCTGG CACACGCCTG CAAACTCACA GAAAAACCGT CGTTACACCT 
TTAGATATGA ACCGCTTTCA GAGTAAAGCT TTCCGTGCTG TGGTCTCACA ACATGCCAGA 
CAGGTCGCAG CCTCCCCAGC AGTAGGACAA CCACTTCAGA AGGAGCCCTC GTTACACCTG 
GATACACCAT CAAAATTCCT GTCCAAGGAC AAACTCTTCA AGCCTTCCTT TGATGTGAAG 
GATGCACTTG CAGCCTTGGA AACTCCAGGA CGTCCCAGCC AACAGAAAAG GAAACTGAGT 
ACGCCACTCT CAGAAGTTAT TGTCAAAAAC TTGCAACTTG CTTTGGCAAA TAGCTCTCGA 
AATGCTGTCG CTCTTTCTGC CAGCCCTCAG CTGAAAGAGG CCCAGTCAGA GAAGGAAGAA 
GCCCCAAAGC CACTTCACAA AGTAGTGGTA TGTGTTAGTA AAAAACTCGG TAAAAAGCAG 
AGTGAACTAA ATGGGATCGC AGCCTCTCTA GGAGCAGATT ACAGGTGGAG TTTTGATGAA 
ACAGTGACTC ATTTCATCTA TCAAGGGCGG CCAAATGACA CTAATCGGGA GTATAAATCT 
GTAAAAGAAA GAGGAGTACA CATTGTTTCC GAGCACTGGC TTTTAGATTG TGCCCAAGAG 
TGTAAACATC TTCCTGAATC TCTTTATCCG CATACTTATA ATCCCAAAAT GAGCTTGGAT 
ATCAGTGCAG TGCAAGATGG CCGACTCTGT AATAGTCGAC TACTCTCAGC TGTGTCTGCA 
ACAAAGGATG ATGAGCCAGA TCCTTTGATT TTAGAAGAAA ATGATGTAGA CAATATGGCC 
ACCAATAATA AAGAGTCAGC ACCATCAAAT GGAAGTGGAA AGAATGACTC TAAAGGAGTT 
CTGACACAGA CCTTAGAGAT GAGAGAGAAC TTTCAGAAGC AGTTACAGGA GATAATGTCT 
GCAACATCAA TAGTGAAACC CCAAGGGCAG AGGACTTCCC TTTCAAGAAG TGGTTGTAAC 
AGCGCATCTT CAACCCCTGA CAGCACTCGC TCTGCTCGCA GTGGACGAAG TAGAGTCCTA 
GAGGCACTGA GGCAGTCTCG TCAAACAGTA CCTGATGTCA ACACAGAGCC TTCCCAAAAT 
GAACAGATTA TTTGGGATGA CCCTACAGCA AGGGAGGAGA GAGCAAGGCT TGCCAGCAAT 
TTGCAGTGGC CTAGTTGTCC CACACAATAC TCTGAGCTTC AGGTTGACAT TCAAAACTTG 
GAGGATTCTC CTTTTCAAAA GCCTTTACAT GATTCAGAAA TTGCTAAACA GGCTGTCTGT 
GATCCTGGAA ACATACGTGT GACTGAAGCT CCCAAACACC CAATCTCTGA AGAACTGGAA 
ACTCCCATAA AAGATAGCCA CCTGATCCCT ACGCCTCAAG CCCCCAGTAT TGCCTTTCCA 
CTCGCCAACC CCCCTGTGGC TCCGCACCCT AGAGAAAAGG TGGATTGGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOPBP1 ( XM_516761.7 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> XP_516761.5 Pan troglodytes DNA topoisomerase II binding protein 1 (TOPBP1), transcript variant X1, mRNA.

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CloneID	OPc07192
Clone ID Related Accession (Same CDS sequence)	XM_516761.7
Accession Version	XM_516761.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4569bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-19
Organism	Pan troglodytes(chimpanzee)
Product	DNA topoisomerase 2-binding protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_036882.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 20, 2018 this sequence version replaced XM_516761.6. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Pan troglodytes Annotation Release 105 Annotation Version :: 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAGAA ATGACAAAGA ACCGTTTTTT GTGAAGTTTT TAAAGTCTTC AGACAATTCC 
AAATGTTTTT TTAAAGCTCT CGAGTCCATA AAAGAATTCC AATCAGAAGA ATATCTTCAG 
ATTATTACAG AAGAAGAGGC ATTGAAGATA AAGGAGAATG ATAGATCACT TTATATCTGT 
GACCCTTTTA GTGGCGTTGT CTTTGATCAC CTCAAAAAGC TTGGCTGCAG AATTGTTGGT 
CCTCAAGTAG TCATATTTTG TATGCACCAC CAGCGATGTG TCCCAAGAGC CGAACATCCA 
GTTTATAATA TGGTTATGTC TGATGTAACC ATATCTTGTA CAAGTCTGGA AAAAGAAAAA 
AGGGAAGAAG TTCATAAATA TGTACAAATG ATGGGCGGAC GAGTATACAG AGACCTTAAT 
GTATCAGTAA CTCACCTTAT TGCAGGAGAA GTTGGTAGCA AAAAATATTT AGTTGCTGCA 
AACCTGAAGA AACCTATTTT GCTTCCCTCT TGGATAAAAA CACTTTGGGA GAAGTCACAA 
GAGAAAAAAA TAACTAGATA TACTGATATA AACATGGAAG ATTTCAAGTG TCCTATTTTT 
CTTGGTTGCA TAATCTGTGT GACTGGCTTA TGTGGCTTAG ACAGGAAAGA AGTTCAGCAA 
CTCACAGTTA AGCATGGAGG TCAATACATG GGACAGTTGA AAATGAATGA ATGTACACAC 
CTCATTGTGC AAGAACCAAA AGGTCAGAAG TATGAGTGTG CCAAGAGATG GAATGTACAC 
TGTGTGACCA CACAGTGGTT TTTTGACAGT ATTGAGAAAG GTTTTTGTCA GGATGAATCC 
ATATACAAGA CAGAACCTAG ACCAGAAGCA AAGACTATGC CCAATTCTTC AACTCCTACC 
AGCCAGATCA ACACAATTGA TAGTCGTACT CTTTCAGATG TCAGCAATAT TTCCAACATA 
AATGCAAGTT GCGTAAGTGA ATCAATATGT AATTCACTTA ACAGCAAACT GGAGCCTACA 
CTTGAAAATC TAGAAAATCT GGATGTCAGT GCATTTCAAG CACCTGAAGA TTTATTAGAT 
GGTTGTCGGA TATATCTTTG CGGTTTTAGT GGCAGAAAGC TAGATAAACT GAGAAGACTT 
ATTAACAGTG GAGGTGGAGT TCGTTTTAAC CAGCTAAATG AAGATGTAAC TCATGTTATT 
GTGGGAGATT ATGATGATGA ATTGAAGCAG TTTTGGAATA AATCAGCCCA CAGGCCTCAT 
GTAGTGGGAG CAAAGTGGTT GCTAGAGTGT TTCAGTAAAG GTTATATGCT TTCTGAAGAA 
CCATATATCC ATGCTAATTA CCAGCCAGTG GAAATTCCAG TTTCACATCA GCCTGAAAGT 
AAAGCAGCTC TTTTAAAAAA GAAGAACAGC AGCTTCTCTA AGAAAGACTT TGCTCCTAGT 
GAAAAGCATG AGCAAGCTGA TGAAGATCTG CTCTCTCAAT ATGAAAATGA TAGCTCCACA 
GTAGTTGAGG CTAAGACGTC TGAAGCCAGG CCCTTTAATG ATTCTACTCA TGCTGAGCCC 
TTGAATGATT CTACTCACAT TTCTTTGCAA GAAGAAAACC AGTCTTCTGT CAGTCATTGT 
GTCCCTGATG TTTCTACAAT TACTGAAGAA GGCTTATTTA GCCAAAAGAG TTTCCTTGTT 
TTGGGTTTTA GTAATGAAAA TGAATCTAAC ATCGCAAACA TCATAAAAGA AAATGCTGGG 
AAAATCATGT CCCTTCTGAG CAGAACTGTT GCGGATTATG CTGTGGTTCC TCTGCTGGGG 
TGTGAAGTGG AAGCCACTGT GGGAGAAGTT GTTACAAATA CATGGCTGGT TACTTGCATA 
GACTATCAGA CTTTGTTTGA TCCAAAGTCG AATCCTCTCT TCACACCAGT CCCAGTAATG 
ACAGGAATGA CTCCTTTAGA GGATTGTGTT ATTTCATTTA GCCAGTGTGC TGGAGCAGAA 
AAAGAGTCTT TAACATTCCT AGCAAACCTC CTTGGAGCAA GTGTTCAAGA ATACTTTGTT 
CGCAAATCCA ATGCAAAGAA AGGCATGTTT GCCAGTACTC ATCTTATACT GAAAGAACGT 
GGTGGCTCTA AATATGAAGC TGCAAAGAAG TGGAATTTAC CTGCAGTTAC TATAGCTTGG 
CTGTTGGAGA CTGCTAGAAC GGGAAAGAGA GCAGACGAAA GCCATTTTCT GATTGAAAAT 
TCATCTAAAG AAGAACGAAG TTTGGAAACA GAAATAACAA ATGGAATCAA TCTAAATTCA 
GATACTGCAG AGCATCCTGG CACACGCCTG CAAACTCACA GAAAAACCGT CGTTACACCT 
TTAGATATGA ACCGCTTTCA GAGTAAAGCT TTCCGTGCTG TGGTCTCACA ACATGCCAGA 
CAGGTCGCAG CCTCCCCAGC AGTAGGACAA CCACTTCAGA AGGAGCCCTC GTTACACCTG 
GATACACCAT CAAAATTCCT GTCCAAGGAC AAACTCTTCA AGCCTTCCTT TGATGTGAAG 
GATGCACTTG CAGCCTTGGA AACTCCAGGA CGTCCCAGCC AACAGAAAAG GAAACTGAGT 
ACGCCACTCT CAGAAGTTAT TGTCAAAAAC TTGCAACTTG CTTTGGCAAA TAGCTCTCGA 
AATGCTGTCG CTCTTTCTGC CAGCCCTCAG CTGAAAGAGG CCCAGTCAGA GAAGGAAGAA 
GCCCCAAAGC CACTTCACAA AGTAGTGGTA TGTGTTAGTA AAAAACTCGG TAAAAAGCAG 
AGTGAACTAA ATGGGATCGC AGCCTCTCTA GGAGCAGATT ACAGGTGGAG TTTTGATGAA 
ACAGTGACTC ATTTCATCTA TCAAGGGCGG CCAAATGACA CTAATCGGGA GTATAAATCT 
GTAAAAGAAA GAGGAGTACA CATTGTTTCC GAGCACTGGC TTTTAGATTG TGCCCAAGAG 
TGTAAACATC TTCCTGAATC TCTTTATCCG CATACTTATA ATCCCAAAAT GAGCTTGGAT 
ATCAGTGCAG TGCAAGATGG CCGACTCTGT AATAGTCGAC TACTCTCAGC TGTGTCTGCA 
ACAAAGGATG ATGAGCCAGA TCCTTTGATT TTAGAAGAAA ATGATGTAGA CAATATGGCC 
ACCAATAATA AAGAGTCAGC ACCATCAAAT GGAAGTGGAA AGAATGACTC TAAAGGAGTT 
CTGACACAGA CCTTAGAGAT GAGAGAGAAC TTTCAGAAGC AGTTACAGGA GATAATGTCT 
GCAACATCAA TAGTGAAACC CCAAGGGCAG AGGACTTCCC TTTCAAGAAG TGGTTGTAAC 
AGCGCATCTT CAACCCCTGA CAGCAGTCGC TCTGCTCGCA GTGGACGAAG TAGAGTCCTA 
GAGGCACTGA GGCAGTCTCG TCAAACAGTA CCTGATGTCA ACACAGAGCC TTCCCAAAAT 
GAACAGATTA TTTGGGATGA CCCTACAGCA AGGGAGGAGA GAGCAAGGCT TGCCAGCAAT 
TTGCAGTGGC CTAGTTGTCC CACACAATAC TCTGAGCTTC AGGTTGACAT TCAAAACTTG 
GAGGATTCTC CTTTTCAAAA GCCTTTACAT GATTCAGAAA TTGCTAAACA GGCTGTCTGT 
GATCCTGGAA ACATACGTGT GACTGAAGCT CCCAAACACC CAATCTCTGA AGAACTGGAA 
ACTCCCATAA AAGATAGCCA CCTGATCCCT ACGCCTCAAG CCCCCAGTAT TGCCTTTCCA 
CTCGCCAACC CCCCTGTGGC TCCGCACCCT AGAGAAAAGA TTATAATGAT AGAGGAGACT 
CATGAAGAAT TAAAAAAACA GTACATATTT CAGTTATCAT CTCTGAATCC TCAAGAACGT 
ATTGACTATT GTCATCTGAT TGAGAAACTA GGTGGATTGG TGATAGAAAA GCAGTGCTTT 
GATCCCACCT GTACACACAT TGTTGTGGGA CATCCACTTC GAAACGAGAA GTATTTAGCC 
TCAGTGGCAG CTGGGAAGTG GGTGCTTCAT CGCTCCTACC TTGAAGCCTG CAGGACTGCT 
GGACACTTCG TGCAGGAAGA AGACTATGAA TGGGGAAGTA GTTCCATACT TGATGTTTTG 
ACTGGAATCA ATGTACAGCA ACGAAGACTA GCACTTGCAG CAATGAGATG GAGAAAAAAA 
ATCCAGCAAA GACAAGAATC TGGCATTGTT GAGGGAGCAT TTAGTGGGTG GAAGGTTATT 
TTACATGTGG ATCAGTCTCG AGAAGCAGGC TTCAAACGCC TTCTTCAGTC AGGAGGAGCA 
AAGGTGCTAC CTGGTCATTC TGTACCTTTA TTTAAAGAGG CCACACATCT TTTTTCTGAC 
TTGAATAAAC TGAAACCAGA TGACTCAGGA GTTAATATAG CAGAAGCTGC TGCCCAGAAC 
GTGTACTGCT TGAGAACAGA ATACATTGCT GATTATCTCA TGCAGGAATC ACCTCCTCAT 
GTAGAAAATT ACTGTCTACC AGAAGCTATT TCATTTATTC AGAATAATAA GGAACTTGGG 
ACTGGATTAT CACAAAAGAG GAAAGCTCCT ACAGAAAAAA ATAAAATCAA ACGACCTAGA 
GTACACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_516761.5
CDS	159..4727
Translation	MSRNDKEPFFVKFLKSSDNSKCFFKALESIKEFQSEEYLQIITEEEALKIKENDRSLYICDPFSGVVFDHLKKLGCRIVGPQVVIFCMHHQRCVPRAEHPVYNMVMSDVTISCTSLEKEKREEVHKYVQMMGGRVYRDLNVSVTHLIAGEVGSKKYLVAANLKKPILLPSWIKTLWEKSQEKKITRYTDINMEDFKCPIFLGCIICVTGLCGLDRKEVQQLTVKHGGQYMGQLKMNECTHLIVQEPKGQKYECAKRWNVHCVTTQWFFDSIEKGFCQDESIYKTEPRPEAKTMPNSSTPTSQINTIDSRTLSDVSNISNINASCVSESICNSLNSKLEPTLENLENLDVSAFQAPEDLLDGCRIYLCGFSGRKLDKLRRLINSGGGVRFNQLNEDVTHVIVGDYDDELKQFWNKSAHRPHVVGAKWLLECFSKGYMLSEEPYIHANYQPVEIPVSHQPESKAALLKKKNSSFSKKDFAPSEKHEQADEDLLSQYENDSSTVVEAKTSEARPFNDSTHAEPLNDSTHISLQEENQSSVSHCVPDVSTITEEGLFSQKSFLVLGFSNENESNIANIIKENAGKIMSLLSRTVADYAVVPLLGCEVEATVGEVVTNTWLVTCIDYQTLFDPKSNPLFTPVPVMTGMTPLEDCVISFSQCAGAEKESLTFLANLLGASVQEYFVRKSNAKKGMFASTHLILKERGGSKYEAAKKWNLPAVTIAWLLETARTGKRADESHFLIENSSKEERSLETEITNGINLNSDTAEHPGTRLQTHRKTVVTPLDMNRFQSKAFRAVVSQHARQVAASPAVGQPLQKEPSLHLDTPSKFLSKDKLFKPSFDVKDALAALETPGRPSQQKRKLSTPLSEVIVKNLQLALANSSRNAVALSASPQLKEAQSEKEEAPKPLHKVVVCVSKKLGKKQSELNGIAASLGADYRWSFDETVTHFIYQGRPNDTNREYKSVKERGVHIVSEHWLLDCAQECKHLPESLYPHTYNPKMSLDISAVQDGRLCNSRLLSAVSATKDDEPDPLILEENDVDNMATNNKESAPSNGSGKNDSKGVLTQTLEMRENFQKQLQEIMSATSIVKPQGQRTSLSRSGCNSASSTPDSSRSARSGRSRVLEALRQSRQTVPDVNTEPSQNEQIIWDDPTAREERARLASNLQWPSCPTQYSELQVDIQNLEDSPFQKPLHDSEIAKQAVCDPGNIRVTEAPKHPISEELETPIKDSHLIPTPQAPSIAFPLANPPVAPHPREKIIMIEETHEELKKQYIFQLSSLNPQERIDYCHLIEKLGGLVIEKQCFDPTCTHIVVGHPLRNEKYLASVAAGKWVLHRSYLEACRTAGHFVQEEDYEWGSSSILDVLTGINVQQRRLALAAMRWRKKIQQRQESGIVEGAFSGWKVILHVDQSREAGFKRLLQSGGAKVLPGHSVPLFKEATHLFSDLNKLKPDDSGVNIAEAAAQNVYCLRTEYIADYLMQESPPHVENYCLPEAISFIQNNKELGTGLSQKRKAPTEKNKIKRPRVH

Target ORF information:

RefSeq Version	XM_516761.7
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes DNA topoisomerase II binding protein 1 (TOPBP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_516761.7

ORF Insert Sequence:

ATGTCCAGAA ATGACAAAGA ACCGTTTTTT GTGAAGTTTT TAAAGTCTTC AGACAATTCC 
AAATGTTTTT TTAAAGCTCT CGAGTCCATA AAAGAATTCC AATCAGAAGA ATATCTTCAG 
ATTATTACAG AAGAAGAGGC ATTGAAGATA AAGGAGAATG ATAGATCACT TTATATCTGT 
GACCCTTTTA GTGGCGTTGT CTTTGATCAC CTCAAAAAGC TTGGCTGCAG AATTGTTGGT 
CCTCAAGTAG TCATATTTTG TATGCACCAC CAGCGATGTG TCCCAAGAGC CGAACATCCA 
GTTTATAATA TGGTTATGTC TGATGTAACC ATATCTTGTA CAAGTCTGGA AAAAGAAAAA 
AGGGAAGAAG TTCATAAATA TGTACAAATG ATGGGCGGAC GAGTATACAG AGACCTTAAT 
GTATCAGTAA CTCACCTTAT TGCAGGAGAA GTTGGTAGCA AAAAATATTT AGTTGCTGCA 
AACCTGAAGA AACCTATTTT GCTTCCCTCT TGGATAAAAA CACTTTGGGA GAAGTCACAA 
GAGAAAAAAA TAACTAGATA TACTGATATA AACATGGAAG ATTTCAAGTG TCCTATTTTT 
CTTGGTTGCA TAATCTGTGT GACTGGCTTA TGTGGCTTAG ACAGGAAAGA AGTTCAGCAA 
CTCACAGTTA AGCATGGAGG TCAATACATG GGACAGTTGA AAATGAATGA ATGTACACAC 
CTCATTGTGC AAGAACCAAA AGGTCAGAAG TATGAGTGTG CCAAGAGATG GAATGTACAC 
TGTGTGACCA CACAGTGGTT TTTTGACAGT ATTGAGAAAG GTTTTTGTCA GGATGAATCC 
ATATACAAGA CAGAACCTAG ACCAGAAGCA AAGACTATGC CCAATTCTTC AACTCCTACC 
AGCCAGATCA ACACAATTGA TAGTCGTACT CTTTCAGATG TCAGCAATAT TTCCAACATA 
AATGCAAGTT GCGTAAGTGA ATCAATATGT AATTCACTTA ACAGCAAACT GGAGCCTACA 
CTTGAAAATC TAGAAAATCT GGATGTCAGT GCATTTCAAG CACCTGAAGA TTTATTAGAT 
GGTTGTCGGA TATATCTTTG CGGTTTTAGT GGCAGAAAGC TAGATAAACT GAGAAGACTT 
ATTAACAGTG GAGGTGGAGT TCGTTTTAAC CAGCTAAATG AAGATGTAAC TCATGTTATT 
GTGGGAGATT ATGATGATGA ATTGAAGCAG TTTTGGAATA AATCAGCCCA CAGGCCTCAT 
GTAGTGGGAG CAAAGTGGTT GCTAGAGTGT TTCAGTAAAG GTTATATGCT TTCTGAAGAA 
CCATATATCC ATGCTAATTA CCAGCCAGTG GAAATTCCAG TTTCACATCA GCCTGAAAGT 
AAAGCAGCTC TTTTAAAAAA GAAGAACAGC AGCTTCTCTA AGAAAGACTT TGCTCCTAGT 
GAAAAGCATG AGCAAGCTGA TGAAGATCTG CTCTCTCAAT ATGAAAATGA TAGCTCCACA 
GTAGTTGAGG CTAAGACGTC TGAAGCCAGG CCCTTTAATG ATTCTACTCA TGCTGAGCCC 
TTGAATGATT CTACTCACAT TTCTTTGCAA GAAGAAAACC AGTCTTCTGT CAGTCATTGT 
GTCCCTGATG TTTCTACAAT TACTGAAGAA GGCTTATTTA GCCAAAAGAG TTTCCTTGTT 
TTGGGTTTTA GTAATGAAAA TGAATCTAAC ATCGCAAACA TCATAAAAGA AAATGCTGGG 
AAAATCATGT CCCTTCTGAG CAGAACTGTT GCGGATTATG CTGTGGTTCC TCTGCTGGGG 
TGTGAAGTGG AAGCCACTGT GGGAGAAGTT GTTACAAATA CATGGCTGGT TACTTGCATA 
GACTATCAGA CTTTGTTTGA TCCAAAGTCG AATCCTCTCT TCACACCAGT CCCAGTAATG 
ACAGGAATGA CTCCTTTAGA GGATTGTGTT ATTTCATTTA GCCAGTGTGC TGGAGCAGAA 
AAAGAGTCTT TAACATTCCT AGCAAACCTC CTTGGAGCAA GTGTTCAAGA ATACTTTGTT 
CGCAAATCCA ATGCAAAGAA AGGCATGTTT GCCAGTACTC ATCTTATACT GAAAGAACGT 
GGTGGCTCTA AATATGAAGC TGCAAAGAAG TGGAATTTAC CTGCAGTTAC TATAGCTTGG 
CTGTTGGAGA CTGCTAGAAC GGGAAAGAGA GCAGACGAAA GCCATTTTCT GATTGAAAAT 
TCATCTAAAG AAGAACGAAG TTTGGAAACA GAAATAACAA ATGGAATCAA TCTAAATTCA 
GATACTGCAG AGCATCCTGG CACACGCCTG CAAACTCACA GAAAAACCGT CGTTACACCT 
TTAGATATGA ACCGCTTTCA GAGTAAAGCT TTCCGTGCTG TGGTCTCACA ACATGCCAGA 
CAGGTCGCAG CCTCCCCAGC AGTAGGACAA CCACTTCAGA AGGAGCCCTC GTTACACCTG 
GATACACCAT CAAAATTCCT GTCCAAGGAC AAACTCTTCA AGCCTTCCTT TGATGTGAAG 
GATGCACTTG CAGCCTTGGA AACTCCAGGA CGTCCCAGCC AACAGAAAAG GAAACTGAGT 
ACGCCACTCT CAGAAGTTAT TGTCAAAAAC TTGCAACTTG CTTTGGCAAA TAGCTCTCGA 
AATGCTGTCG CTCTTTCTGC CAGCCCTCAG CTGAAAGAGG CCCAGTCAGA GAAGGAAGAA 
GCCCCAAAGC CACTTCACAA AGTAGTGGTA TGTGTTAGTA AAAAACTCGG TAAAAAGCAG 
AGTGAACTAA ATGGGATCGC AGCCTCTCTA GGAGCAGATT ACAGGTGGAG TTTTGATGAA 
ACAGTGACTC ATTTCATCTA TCAAGGGCGG CCAAATGACA CTAATCGGGA GTATAAATCT 
GTAAAAGAAA GAGGAGTACA CATTGTTTCC GAGCACTGGC TTTTAGATTG TGCCCAAGAG 
TGTAAACATC TTCCTGAATC TCTTTATCCG CATACTTATA ATCCCAAAAT GAGCTTGGAT 
ATCAGTGCAG TGCAAGATGG CCGACTCTGT AATAGTCGAC TACTCTCAGC TGTGTCTGCA 
ACAAAGGATG ATGAGCCAGA TCCTTTGATT TTAGAAGAAA ATGATGTAGA CAATATGGCC 
ACCAATAATA AAGAGTCAGC ACCATCAAAT GGAAGTGGAA AGAATGACTC TAAAGGAGTT 
CTGACACAGA CCTTAGAGAT GAGAGAGAAC TTTCAGAAGC AGTTACAGGA GATAATGTCT 
GCAACATCAA TAGTGAAACC CCAAGGGCAG AGGACTTCCC TTTCAAGAAG TGGTTGTAAC 
AGCGCATCTT CAACCCCTGA CAGCAGTCGC TCTGCTCGCA GTGGACGAAG TAGAGTCCTA 
GAGGCACTGA GGCAGTCTCG TCAAACAGTA CCTGATGTCA ACACAGAGCC TTCCCAAAAT 
GAACAGATTA TTTGGGATGA CCCTACAGCA AGGGAGGAGA GAGCAAGGCT TGCCAGCAAT 
TTGCAGTGGC CTAGTTGTCC CACACAATAC TCTGAGCTTC AGGTTGACAT TCAAAACTTG 
GAGGATTCTC CTTTTCAAAA GCCTTTACAT GATTCAGAAA TTGCTAAACA GGCTGTCTGT 
GATCCTGGAA ACATACGTGT GACTGAAGCT CCCAAACACC CAATCTCTGA AGAACTGGAA 
ACTCCCATAA AAGATAGCCA CCTGATCCCT ACGCCTCAAG CCCCCAGTAT TGCCTTTCCA 
CTCGCCAACC CCCCTGTGGC TCCGCACCCT AGAGAAAAGA TTATAATGAT AGAGGAGACT 
CATGAAGAAT TAAAAAAACA GTACATATTT CAGTTATCAT CTCTGAATCC TCAAGAACGT 
ATTGACTATT GTCATCTGAT TGAGAAACTA GGTGGATTGG TGATAGAAAA GCAGTGCTTT 
GATCCCACCT GTACACACAT TGTTGTGGGA CATCCACTTC GAAACGAGAA GTATTTAGCC 
TCAGTGGCAG CTGGGAAGTG GGTGCTTCAT CGCTCCTACC TTGAAGCCTG CAGGACTGCT 
GGACACTTCG TGCAGGAAGA AGACTATGAA TGGGGAAGTA GTTCCATACT TGATGTTTTG 
ACTGGAATCA ATGTACAGCA ACGAAGACTA GCACTTGCAG CAATGAGATG GAGAAAAAAA 
ATCCAGCAAA GACAAGAATC TGGCATTGTT GAGGGAGCAT TTAGTGGGTG GAAGGTTATT 
TTACATGTGG ATCAGTCTCG AGAAGCAGGC TTCAAACGCC TTCTTCAGTC AGGAGGAGCA 
AAGGTGCTAC CTGGTCATTC TGTACCTTTA TTTAAAGAGG CCACACATCT TTTTTCTGAC 
TTGAATAAAC TGAAACCAGA TGACTCAGGA GTTAATATAG CAGAAGCTGC TGCCCAGAAC 
GTGTACTGCT TGAGAACAGA ATACATTGCT GATTATCTCA TGCAGGAATC ACCTCCTCAT 
GTAGAAAATT ACTGTCTACC AGAAGCTATT TCATTTATTC AGAATAATAA GGAACTTGGG 
ACTGGATTAT CACAAAAGAG GAAAGCTCCT ACAGAAAAAA ATAAAATCAA ACGACCTAGA 
GTACACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOPBP1 ( XM_009446506.3 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> XP_009444781.3 Pan troglodytes DNA topoisomerase II binding protein 1 (TOPBP1), transcript variant X2, mRNA.

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CloneID	OPc38344
Clone ID Related Accession (Same CDS sequence)	XM_009446506.3
Accession Version	XM_009446506.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-19
Organism	Pan troglodytes(chimpanzee)
Product	DNA topoisomerase 2-binding protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_036882.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 20, 2018 this sequence version replaced XM_009446506.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Pan troglodytes Annotation Release 105 Annotation Version :: 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAGAA ATGACAAAGA ACCGTTTTTT GTGAAGTTTT TAAAGTCTTC AGACAATTCC 
AAATGTTTTT TTAAAGCTCT CGAGTCCATA AAAGAATTCC AATCAGAAGA ATATCTTCAG 
ATTATTACAG AAGAAGAGGC ATTGAAGATA AAGGAGAATG ATAGATCACT TTATATCTGT 
GACCCTTTTA GTGGCGTTGT CTTTGATCAC CTCAAAAAGC TTGGCTGCAG AATTGTTGGT 
CCTCAAGTAG TCATATTTTG TATGCACCAC CAGCGATGTG TCCCAAGAGC CGAACATCCA 
GTTTATAATA TGGTTATGTC TGATGTAACC ATATCTTGTA CAAGTCTGGA AAAAGAAAAA 
AGGGAAGAAG TTCATAAATA TGTACAAATG ATGGGCGGAC GAGTATACAG AGACCTTAAT 
GTATCAGTAA CTCACCTTAT TGCAGGAGAA GTTGGTAGCA AAAAATATTT AGTTGCTGCA 
AACCTGAAGA AACCTATTTT GCTTCCCTCT TGGATAAAAA CACTTTGGGA GAAGTCACAA 
GAGAAAAAAA TAACTAGATA TACTGATATA AACATGGAAG ATTTCAAGTG TCCTATTTTT 
CTTGGTTGCA TAATCTGTGT GACTGGCTTA TGTGGCTTAG ACAGGAAAGA AGTTCAGCAA 
CTCACAGTTA AGCATGGAGG TCAATACATG GGACAGTTGA AAATGAATGA ATGTACACAC 
CTCATTGTGC AAGAACCAAA AGGTCAGAAG TATGAGTGTG CCAAGAGATG GAATGTACAC 
TGTGTGACCA CACAGTGGTT TTTTGACAGT ATTGAGAAAG GTTTTTGTCA GGATGAATCC 
ATATACAAGA CAGAACCTAG ACCAGAAGCA AAGACTATGC CCAATTCTTC AACTCCTACC 
AGCCAGATCA ACACAATTGA TAATGTCAGC AATATTTCCA ACATAAATGC AAGTTGCGTA 
AGTGAATCAA TATGTAATTC ACTTAACAGC AAACTGGAGC CTACACTTGA AAATCTAGAA 
AATCTGGATG TCAGTGCATT TCAAGCACCT GAAGATTTAT TAGATGGTTG TCGGATATAT 
CTTTGCGGTT TTAGTGGCAG AAAGCTAGAT AAACTGAGAA GACTTATTAA CAGTGGAGGT 
GGAGTTCGTT TTAACCAGCT AAATGAAGAT GTAACTCATG TTATTGTGGG AGATTATGAT 
GATGAATTGA AGCAGTTTTG GAATAAATCA GCCCACAGGC CTCATGTAGT GGGAGCAAAG 
TGGTTGCTAG AGTGTTTCAG TAAAGGTTAT ATGCTTTCTG AAGAACCATA TATCCATGCT 
AATTACCAGC CAGTGGAAAT TCCAGTTTCA CATCAGCCTG AAAGTAAAGC AGCTCTTTTA 
AAAAAGAAGA ACAGCAGCTT CTCTAAGAAA GACTTTGCTC CTAGTGAAAA GCATGAGCAA 
GCTGATGAAG ATCTGCTCTC TCAATATGAA AATGATAGCT CCACAGTAGT TGAGGCTAAG 
ACGTCTGAAG CCAGGCCCTT TAATGATTCT ACTCATGCTG AGCCCTTGAA TGATTCTACT 
CACATTTCTT TGCAAGAAGA AAACCAGTCT TCTGTCAGTC ATTGTGTCCC TGATGTTTCT 
ACAATTACTG AAGAAGGCTT ATTTAGCCAA AAGAGTTTCC TTGTTTTGGG TTTTAGTAAT 
GAAAATGAAT CTAACATCGC AAACATCATA AAAGAAAATG CTGGGAAAAT CATGTCCCTT 
CTGAGCAGAA CTGTTGCGGA TTATGCTGTG GTTCCTCTGC TGGGGTGTGA AGTGGAAGCC 
ACTGTGGGAG AAGTTGTTAC AAATACATGG CTGGTTACTT GCATAGACTA TCAGACTTTG 
TTTGATCCAA AGTCGAATCC TCTCTTCACA CCAGTCCCAG TAATGACAGG AATGACTCCT 
TTAGAGGATT GTGTTATTTC ATTTAGCCAG TGTGCTGGAG CAGAAAAAGA GTCTTTAACA 
TTCCTAGCAA ACCTCCTTGG AGCAAGTGTT CAAGAATACT TTGTTCGCAA ATCCAATGCA 
AAGAAAGGCA TGTTTGCCAG TACTCATCTT ATACTGAAAG AACGTGGTGG CTCTAAATAT 
GAAGCTGCAA AGAAGTGGAA TTTACCTGCA GTTACTATAG CTTGGCTGTT GGAGACTGCT 
AGAACGGGAA AGAGAGCAGA CGAAAGCCAT TTTCTGATTG AAAATTCATC TAAAGAAGAA 
CGAAGTTTGG AAACAGAAAT AACAAATGGA ATCAATCTAA ATTCAGATAC TGCAGAGCAT 
CCTGGCACAC GCCTGCAAAC TCACAGAAAA ACCGTCGTTA CACCTTTAGA TATGAACCGC 
TTTCAGAGTA AAGCTTTCCG TGCTGTGGTC TCACAACATG CCAGACAGGT CGCAGCCTCC 
CCAGCAGTAG GACAACCACT TCAGAAGGAG CCCTCGTTAC ACCTGGATAC ACCATCAAAA 
TTCCTGTCCA AGGACAAACT CTTCAAGCCT TCCTTTGATG TGAAGGATGC ACTTGCAGCC 
TTGGAAACTC CAGGACGTCC CAGCCAACAG AAAAGGAAAC TGAGTACGCC ACTCTCAGAA 
GTTATTGTCA AAAACTTGCA ACTTGCTTTG GCAAATAGCT CTCGAAATGC TGTCGCTCTT 
TCTGCCAGCC CTCAGCTGAA AGAGGCCCAG TCAGAGAAGG AAGAAGCCCC AAAGCCACTT 
CACAAAGTAG TGGTATGTGT TAGTAAAAAA CTCGGTAAAA AGCAGAGTGA ACTAAATGGG 
ATCGCAGCCT CTCTAGGAGC AGATTACAGG TGGAGTTTTG ATGAAACAGT GACTCATTTC 
ATCTATCAAG GGCGGCCAAA TGACACTAAT CGGGAGTATA AATCTGTAAA AGAAAGAGGA 
GTACACATTG TTTCCGAGCA CTGGCTTTTA GATTGTGCCC AAGAGTGTAA ACATCTTCCT 
GAATCTCTTT ATCCGCATAC TTATAATCCC AAAATGAGCT TGGATATCAG TGCAGTGCAA 
GATGGCCGAC TCTGTAATAG TCGACTACTC TCAGCTGTGT CTGCAACAAA GGATGATGAG 
CCAGATCCTT TGATTTTAGA AGAAAATGAT GTAGACAATA TGGCCACCAA TAATAAAGAG 
TCAGCACCAT CAAATGGAAG TGGAAAGAAT GACTCTAAAG GAGTTCTGAC ACAGACCTTA 
GAGATGAGAG AGAACTTTCA GAAGCAGTTA CAGGAGATAA TGTCTGCAAC ATCAATAGTG 
AAACCCCAAG GGCAGAGGAC TTCCCTTTCA AGAAGTGGTT GTAACAGCGC ATCTTCAACC 
CCTGACAGCA GTCGCTCTGC TCGCAGTGGA CGAAGTAGAG TCCTAGAGGC ACTGAGGCAG 
TCTCGTCAAA CAGTACCTGA TGTCAACACA GAGCCTTCCC AAAATGAACA GATTATTTGG 
GATGACCCTA CAGCAAGGGA GGAGAGAGCA AGGCTTGCCA GCAATTTGCA GTGGCCTAGT 
TGTCCCACAC AATACTCTGA GCTTCAGGTT GACATTCAAA ACTTGGAGGA TTCTCCTTTT 
CAAAAGCCTT TACATGATTC AGAAATTGCT AAACAGGCTG TCTGTGATCC TGGAAACATA 
CGTGTGACTG AAGCTCCCAA ACACCCAATC TCTGAAGAAC TGGAAACTCC CATAAAAGAT 
AGCCACCTGA TCCCTACGCC TCAAGCCCCC AGTATTGCCT TTCCACTCGC CAACCCCCCT 
GTGGCTCCGC ACCCTAGAGA AAAGATTATA ATGATAGAGG AGACTCATGA AGAATTAAAA 
AAACAGTACA TATTTCAGTT ATCATCTCTG AATCCTCAAG AACGTATTGA CTATTGTCAT 
CTGATTGAGA AACTAGGTGG ATTGGTGATA GAAAAGCAGT GCTTTGATCC CACCTGTACA 
CACATTGTTG TGGGACATCC ACTTCGAAAC GAGAAGTATT TAGCCTCAGT GGCAGCTGGG 
AAGTGGGTGC TTCATCGCTC CTACCTTGAA GCCTGCAGGA CTGCTGGACA CTTCGTGCAG 
GAAGAAGACT ATGAATGGGG AAGTAGTTCC ATACTTGATG TTTTGACTGG AATCAATGTA 
CAGCAACGAA GACTAGCACT TGCAGCAATG AGATGGAGAA AAAAAATCCA GCAAAGACAA 
GAATCTGGCA TTGTTGAGGG AGCATTTAGT GGGTGGAAGG TTATTTTACA TGTGGATCAG 
TCTCGAGAAG CAGGCTTCAA ACGCCTTCTT CAGTCAGGAG GAGCAAAGGT GCTACCTGGT 
CATTCTGTAC CTTTATTTAA AGAGGCCACA CATCTTTTTT CTGACTTGAA TAAACTGAAA 
CCAGATGACT CAGGAGTTAA TATAGCAGAA GCTGCTGCCC AGAACGTGTA CTGCTTGAGA 
ACAGAATACA TTGCTGATTA TCTCATGCAG GAATCACCTC CTCATGTAGA AAATTACTGT 
CTACCAGAAG CTATTTCATT TATTCAGAAT AATAAGGAAC TTGGGACTGG ATTATCACAA 
AAGAGGAAAG CTCCTACAGA AAAAAATAAA ATCAAACGAC CTAGAGTACA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_009444781.3
CDS	159..4712
Translation	MSRNDKEPFFVKFLKSSDNSKCFFKALESIKEFQSEEYLQIITEEEALKIKENDRSLYICDPFSGVVFDHLKKLGCRIVGPQVVIFCMHHQRCVPRAEHPVYNMVMSDVTISCTSLEKEKREEVHKYVQMMGGRVYRDLNVSVTHLIAGEVGSKKYLVAANLKKPILLPSWIKTLWEKSQEKKITRYTDINMEDFKCPIFLGCIICVTGLCGLDRKEVQQLTVKHGGQYMGQLKMNECTHLIVQEPKGQKYECAKRWNVHCVTTQWFFDSIEKGFCQDESIYKTEPRPEAKTMPNSSTPTSQINTIDNVSNISNINASCVSESICNSLNSKLEPTLENLENLDVSAFQAPEDLLDGCRIYLCGFSGRKLDKLRRLINSGGGVRFNQLNEDVTHVIVGDYDDELKQFWNKSAHRPHVVGAKWLLECFSKGYMLSEEPYIHANYQPVEIPVSHQPESKAALLKKKNSSFSKKDFAPSEKHEQADEDLLSQYENDSSTVVEAKTSEARPFNDSTHAEPLNDSTHISLQEENQSSVSHCVPDVSTITEEGLFSQKSFLVLGFSNENESNIANIIKENAGKIMSLLSRTVADYAVVPLLGCEVEATVGEVVTNTWLVTCIDYQTLFDPKSNPLFTPVPVMTGMTPLEDCVISFSQCAGAEKESLTFLANLLGASVQEYFVRKSNAKKGMFASTHLILKERGGSKYEAAKKWNLPAVTIAWLLETARTGKRADESHFLIENSSKEERSLETEITNGINLNSDTAEHPGTRLQTHRKTVVTPLDMNRFQSKAFRAVVSQHARQVAASPAVGQPLQKEPSLHLDTPSKFLSKDKLFKPSFDVKDALAALETPGRPSQQKRKLSTPLSEVIVKNLQLALANSSRNAVALSASPQLKEAQSEKEEAPKPLHKVVVCVSKKLGKKQSELNGIAASLGADYRWSFDETVTHFIYQGRPNDTNREYKSVKERGVHIVSEHWLLDCAQECKHLPESLYPHTYNPKMSLDISAVQDGRLCNSRLLSAVSATKDDEPDPLILEENDVDNMATNNKESAPSNGSGKNDSKGVLTQTLEMRENFQKQLQEIMSATSIVKPQGQRTSLSRSGCNSASSTPDSSRSARSGRSRVLEALRQSRQTVPDVNTEPSQNEQIIWDDPTAREERARLASNLQWPSCPTQYSELQVDIQNLEDSPFQKPLHDSEIAKQAVCDPGNIRVTEAPKHPISEELETPIKDSHLIPTPQAPSIAFPLANPPVAPHPREKIIMIEETHEELKKQYIFQLSSLNPQERIDYCHLIEKLGGLVIEKQCFDPTCTHIVVGHPLRNEKYLASVAAGKWVLHRSYLEACRTAGHFVQEEDYEWGSSSILDVLTGINVQQRRLALAAMRWRKKIQQRQESGIVEGAFSGWKVILHVDQSREAGFKRLLQSGGAKVLPGHSVPLFKEATHLFSDLNKLKPDDSGVNIAEAAAQNVYCLRTEYIADYLMQESPPHVENYCLPEAISFIQNNKELGTGLSQKRKAPTEKNKIKRPRVH

Target ORF information:

RefSeq Version	XM_009446506.3
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes DNA topoisomerase II binding protein 1 (TOPBP1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_009446506.3

ORF Insert Sequence:

ATGTCCAGAA ATGACAAAGA ACCGTTTTTT GTGAAGTTTT TAAAGTCTTC AGACAATTCC 
AAATGTTTTT TTAAAGCTCT CGAGTCCATA AAAGAATTCC AATCAGAAGA ATATCTTCAG 
ATTATTACAG AAGAAGAGGC ATTGAAGATA AAGGAGAATG ATAGATCACT TTATATCTGT 
GACCCTTTTA GTGGCGTTGT CTTTGATCAC CTCAAAAAGC TTGGCTGCAG AATTGTTGGT 
CCTCAAGTAG TCATATTTTG TATGCACCAC CAGCGATGTG TCCCAAGAGC CGAACATCCA 
GTTTATAATA TGGTTATGTC TGATGTAACC ATATCTTGTA CAAGTCTGGA AAAAGAAAAA 
AGGGAAGAAG TTCATAAATA TGTACAAATG ATGGGCGGAC GAGTATACAG AGACCTTAAT 
GTATCAGTAA CTCACCTTAT TGCAGGAGAA GTTGGTAGCA AAAAATATTT AGTTGCTGCA 
AACCTGAAGA AACCTATTTT GCTTCCCTCT TGGATAAAAA CACTTTGGGA GAAGTCACAA 
GAGAAAAAAA TAACTAGATA TACTGATATA AACATGGAAG ATTTCAAGTG TCCTATTTTT 
CTTGGTTGCA TAATCTGTGT GACTGGCTTA TGTGGCTTAG ACAGGAAAGA AGTTCAGCAA 
CTCACAGTTA AGCATGGAGG TCAATACATG GGACAGTTGA AAATGAATGA ATGTACACAC 
CTCATTGTGC AAGAACCAAA AGGTCAGAAG TATGAGTGTG CCAAGAGATG GAATGTACAC 
TGTGTGACCA CACAGTGGTT TTTTGACAGT ATTGAGAAAG GTTTTTGTCA GGATGAATCC 
ATATACAAGA CAGAACCTAG ACCAGAAGCA AAGACTATGC CCAATTCTTC AACTCCTACC 
AGCCAGATCA ACACAATTGA TAATGTCAGC AATATTTCCA ACATAAATGC AAGTTGCGTA 
AGTGAATCAA TATGTAATTC ACTTAACAGC AAACTGGAGC CTACACTTGA AAATCTAGAA 
AATCTGGATG TCAGTGCATT TCAAGCACCT GAAGATTTAT TAGATGGTTG TCGGATATAT 
CTTTGCGGTT TTAGTGGCAG AAAGCTAGAT AAACTGAGAA GACTTATTAA CAGTGGAGGT 
GGAGTTCGTT TTAACCAGCT AAATGAAGAT GTAACTCATG TTATTGTGGG AGATTATGAT 
GATGAATTGA AGCAGTTTTG GAATAAATCA GCCCACAGGC CTCATGTAGT GGGAGCAAAG 
TGGTTGCTAG AGTGTTTCAG TAAAGGTTAT ATGCTTTCTG AAGAACCATA TATCCATGCT 
AATTACCAGC CAGTGGAAAT TCCAGTTTCA CATCAGCCTG AAAGTAAAGC AGCTCTTTTA 
AAAAAGAAGA ACAGCAGCTT CTCTAAGAAA GACTTTGCTC CTAGTGAAAA GCATGAGCAA 
GCTGATGAAG ATCTGCTCTC TCAATATGAA AATGATAGCT CCACAGTAGT TGAGGCTAAG 
ACGTCTGAAG CCAGGCCCTT TAATGATTCT ACTCATGCTG AGCCCTTGAA TGATTCTACT 
CACATTTCTT TGCAAGAAGA AAACCAGTCT TCTGTCAGTC ATTGTGTCCC TGATGTTTCT 
ACAATTACTG AAGAAGGCTT ATTTAGCCAA AAGAGTTTCC TTGTTTTGGG TTTTAGTAAT 
GAAAATGAAT CTAACATCGC AAACATCATA AAAGAAAATG CTGGGAAAAT CATGTCCCTT 
CTGAGCAGAA CTGTTGCGGA TTATGCTGTG GTTCCTCTGC TGGGGTGTGA AGTGGAAGCC 
ACTGTGGGAG AAGTTGTTAC AAATACATGG CTGGTTACTT GCATAGACTA TCAGACTTTG 
TTTGATCCAA AGTCGAATCC TCTCTTCACA CCAGTCCCAG TAATGACAGG AATGACTCCT 
TTAGAGGATT GTGTTATTTC ATTTAGCCAG TGTGCTGGAG CAGAAAAAGA GTCTTTAACA 
TTCCTAGCAA ACCTCCTTGG AGCAAGTGTT CAAGAATACT TTGTTCGCAA ATCCAATGCA 
AAGAAAGGCA TGTTTGCCAG TACTCATCTT ATACTGAAAG AACGTGGTGG CTCTAAATAT 
GAAGCTGCAA AGAAGTGGAA TTTACCTGCA GTTACTATAG CTTGGCTGTT GGAGACTGCT 
AGAACGGGAA AGAGAGCAGA CGAAAGCCAT TTTCTGATTG AAAATTCATC TAAAGAAGAA 
CGAAGTTTGG AAACAGAAAT AACAAATGGA ATCAATCTAA ATTCAGATAC TGCAGAGCAT 
CCTGGCACAC GCCTGCAAAC TCACAGAAAA ACCGTCGTTA CACCTTTAGA TATGAACCGC 
TTTCAGAGTA AAGCTTTCCG TGCTGTGGTC TCACAACATG CCAGACAGGT CGCAGCCTCC 
CCAGCAGTAG GACAACCACT TCAGAAGGAG CCCTCGTTAC ACCTGGATAC ACCATCAAAA 
TTCCTGTCCA AGGACAAACT CTTCAAGCCT TCCTTTGATG TGAAGGATGC ACTTGCAGCC 
TTGGAAACTC CAGGACGTCC CAGCCAACAG AAAAGGAAAC TGAGTACGCC ACTCTCAGAA 
GTTATTGTCA AAAACTTGCA ACTTGCTTTG GCAAATAGCT CTCGAAATGC TGTCGCTCTT 
TCTGCCAGCC CTCAGCTGAA AGAGGCCCAG TCAGAGAAGG AAGAAGCCCC AAAGCCACTT 
CACAAAGTAG TGGTATGTGT TAGTAAAAAA CTCGGTAAAA AGCAGAGTGA ACTAAATGGG 
ATCGCAGCCT CTCTAGGAGC AGATTACAGG TGGAGTTTTG ATGAAACAGT GACTCATTTC 
ATCTATCAAG GGCGGCCAAA TGACACTAAT CGGGAGTATA AATCTGTAAA AGAAAGAGGA 
GTACACATTG TTTCCGAGCA CTGGCTTTTA GATTGTGCCC AAGAGTGTAA ACATCTTCCT 
GAATCTCTTT ATCCGCATAC TTATAATCCC AAAATGAGCT TGGATATCAG TGCAGTGCAA 
GATGGCCGAC TCTGTAATAG TCGACTACTC TCAGCTGTGT CTGCAACAAA GGATGATGAG 
CCAGATCCTT TGATTTTAGA AGAAAATGAT GTAGACAATA TGGCCACCAA TAATAAAGAG 
TCAGCACCAT CAAATGGAAG TGGAAAGAAT GACTCTAAAG GAGTTCTGAC ACAGACCTTA 
GAGATGAGAG AGAACTTTCA GAAGCAGTTA CAGGAGATAA TGTCTGCAAC ATCAATAGTG 
AAACCCCAAG GGCAGAGGAC TTCCCTTTCA AGAAGTGGTT GTAACAGCGC ATCTTCAACC 
CCTGACAGCA GTCGCTCTGC TCGCAGTGGA CGAAGTAGAG TCCTAGAGGC ACTGAGGCAG 
TCTCGTCAAA CAGTACCTGA TGTCAACACA GAGCCTTCCC AAAATGAACA GATTATTTGG 
GATGACCCTA CAGCAAGGGA GGAGAGAGCA AGGCTTGCCA GCAATTTGCA GTGGCCTAGT 
TGTCCCACAC AATACTCTGA GCTTCAGGTT GACATTCAAA ACTTGGAGGA TTCTCCTTTT 
CAAAAGCCTT TACATGATTC AGAAATTGCT AAACAGGCTG TCTGTGATCC TGGAAACATA 
CGTGTGACTG AAGCTCCCAA ACACCCAATC TCTGAAGAAC TGGAAACTCC CATAAAAGAT 
AGCCACCTGA TCCCTACGCC TCAAGCCCCC AGTATTGCCT TTCCACTCGC CAACCCCCCT 
GTGGCTCCGC ACCCTAGAGA AAAGATTATA ATGATAGAGG AGACTCATGA AGAATTAAAA 
AAACAGTACA TATTTCAGTT ATCATCTCTG AATCCTCAAG AACGTATTGA CTATTGTCAT 
CTGATTGAGA AACTAGGTGG ATTGGTGATA GAAAAGCAGT GCTTTGATCC CACCTGTACA 
CACATTGTTG TGGGACATCC ACTTCGAAAC GAGAAGTATT TAGCCTCAGT GGCAGCTGGG 
AAGTGGGTGC TTCATCGCTC CTACCTTGAA GCCTGCAGGA CTGCTGGACA CTTCGTGCAG 
GAAGAAGACT ATGAATGGGG AAGTAGTTCC ATACTTGATG TTTTGACTGG AATCAATGTA 
CAGCAACGAA GACTAGCACT TGCAGCAATG AGATGGAGAA AAAAAATCCA GCAAAGACAA 
GAATCTGGCA TTGTTGAGGG AGCATTTAGT GGGTGGAAGG TTATTTTACA TGTGGATCAG 
TCTCGAGAAG CAGGCTTCAA ACGCCTTCTT CAGTCAGGAG GAGCAAAGGT GCTACCTGGT 
CATTCTGTAC CTTTATTTAA AGAGGCCACA CATCTTTTTT CTGACTTGAA TAAACTGAAA 
CCAGATGACT CAGGAGTTAA TATAGCAGAA GCTGCTGCCC AGAACGTGTA CTGCTTGAGA 
ACAGAATACA TTGCTGATTA TCTCATGCAG GAATCACCTC CTCATGTAGA AAATTACTGT 
CTACCAGAAG CTATTTCATT TATTCAGAAT AATAAGGAAC TTGGGACTGG ATTATCACAA 
AAGAGGAAAG CTCCTACAGA AAAAAATAAA ATCAAACGAC CTAGAGTACA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOPBP1 ( XM_516761.6 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> XP_516761.4 Pan troglodytes topoisomerase (DNA) II binding protein 1 (TOPBP1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OPc82704
Clone ID Related Accession (Same CDS sequence)	XM_516761.6
Accession Version	XM_516761.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4569bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-01
Organism	Pan troglodytes(chimpanzee)
Product	DNA topoisomerase 2-binding protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006490.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 2, 2016 this sequence version replaced XM_516761.5. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Pan troglodytes Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAGAA ATGACAAAGA ACCGTTTTTT GTGAAGTTTT TAAAGTCTTC AGACAATTCC 
AAATGTTTTT TTAAAGCTCT CGAGTCCATA AAAGAATTCC AATCAGAAGA ATATCTTCAG 
ATTATTACAG AAGAAGAGGC ATTGAAGATA AAGGAGAATG ATAGATCACT TTATATCTGT 
GACCCTTTTA GTGGCGTTGT CTTTGATCAC CTCAAAAAGC TTGGCTGCAG AATTGTTGGT 
CCTCAAGTAG TCATATTTTG TATGCACCAC CAGCGATGTG TCCCAAGAGC CGAACATCCA 
GTTTATAATA TGGTTATGTC TGATGTAACC ATATCTTGTA CAAGTCTGGA AAAAGAAAAA 
AGGGAAGAAG TTCATAAATA TGTACAAATG ATGGGCGGAC GAGTATACAG AGACCTTAAT 
GTATCAGTAA CTCACCTTAT TGCAGGAGAA GTTGGTAGCA AAAAATATTT AGTTGCTGCA 
AACCTGAAGA AACCTATTTT GCTTCCCTCT TGGATAAAAA CACTTTGGGA GAAGTCACAA 
GAGAAAAAAA TAACTAGATA TACTGATATA AACATGGAAG ATTTCAAGTG TCCTATTTTT 
CTTGGTTGCA TAATCTGTGT GACTGGCTTA TGTGGCTTAG ACAGGAAAGA AGTTCAGCAA 
CTCACAGTTA AGCATGGAGG TCAATACATG GGACAGTTGA AAATGAATGA ATGTACACAC 
CTCATTGTGC AAGAACCAAA AGGTCAGAAG TATGAGTGTG CCAAGAGATG GAATGTACAC 
TGTGTGACCA CACAGTGGTT TTTTGACAGT ATTGAGAAAG GTTTTTGTCA GGATGAATCC 
ATATACAAGA CAGAACCTAG ACCAGAAGCA AAGACTATGC CCAATTCTTC AACTCCTACC 
AGCCAGATCA ACACAATTGA TAGTCGTACT CTTTCAGATG TCAGCAATAT TTCCAACATA 
AATGCAAGTT GCGTAAGTGA ATCAATATGT AATTCACTTA ACAGCAAACT GGAGCCTACA 
CTTGAAAATC TAGAAAATCT GGATGTCAGT GCATTTCAAG CACCTGAAGA TTTATTAGAT 
GGTTGTCGGA TATATCTTTG CGGTTTTAGT GGCAGAAAGC TAGATAAACT GAGAAGACTT 
ATTAACAGTG GAGGTGGAGT TCGTTTTAAC CAGCTAAATG AAGATGTAAC TCATGTTATT 
GTGGGAGATT ATGATGATGA ATTGAAGCAG TTTTGGAATA AATCAGCCCA CAGGCCTCAT 
GTAGTGGGAG CAAAGTGGTT GCTAGAGTGT TTCAGTAAAG GTTATATGCT TTCTGAAGAA 
CCATATATCC ATGCTAATTA CCAGCCAGTG GAAATTCCAG TTTCACATCA GCCTGAAAGT 
AAAGCAGCTC TTTTAAAAAA GAAGAACAGC AGCTTCTCTA AGAAAGACTT TGCTCCTAGT 
GAAAAGCATG AGCAAGCTGA TGAAGATCTG CTCTCTCAAT ATGAAAATGA TAGCTCCACA 
GTAGTTGAGG CTAAGACGTC TGAAGCCAGG CCCTTTAATG ATTCTACTCA TGCTGAGCCC 
TTGAATGATT CTACTCACAT TTCTTTGCAA GAAGAAAACC AGTCTTCTGT CAGTCATTGT 
GTCCCTGATG TTTCTACAAT TACTGAAGAA GGCTTATTTA GCCAAAAGAG TTTCCTTGTT 
TTGGGTTTTA GTAATGAAAA TGAATCTAAC ATCGCAAACA TCATAAAAGA AAATGCTGGG 
AAAATCATGT CCCTTCTGAG CAGAACTGTT GCGGATTATG CTGTGGTTCC TCTGCTGGGG 
TGTGAAGTGG AAGCCACTGT GGGAGAAGTT GTTACAAATA CATGGCTGGT TACTTGCATA 
GACTATCAGA CTTTGTTTGA TCCAAAGTCG AATCCTCTCT TCACACCAGT CCCAGTAATG 
ACAGGAATGA CTCCTTTAGA GGATTGTGTT ATTTCATTTA GCCAGTGTGC TGGAGCAGAA 
AAAGAGTCTT TAACATTCCT AGCAAACCTC CTTGGAGCAA GTGTTCAAGA ATACTTTGTT 
CGCAAATCCA ATGCAAAGAA AGGCATGTTT GCCAGTACTC ATCTTATACT GAAAGAACGT 
GGTGGCTCTA AATATGAAGC TGCAAAGAAG TGGAATTTAC CTGCAGTTAC TATAGCTTGG 
CTGTTGGAGA CTGCTAGAAC GGGAAAGAGA GCAGACGAAA GCCATTTTCT GATTGAAAAT 
TCATCTAAAG AAGAACGAAG TTTGGAAACA GAAATAACAA ATGGAATCAA TCTAAATTCA 
GATACTGCAG AGCATCCTGG CACACGCCTG CAAACTCACA GAAAAACCGT CGTTACACCT 
TTAGATATGA ACCGCTTTCA GAGTAAAGCT TTCCGTGCTG TGGTCTCACA ACATGCCAGA 
CAGGTCGCAG CCTCCCCAGC AGTAGGACAA CCACTTCAGA AGGAGCCCTC GTTACACCTG 
GATACACCAT CAAAATTCCT GTCCAAGGAC AAACTCTTCA AGCCTTCCTT TGATGTGAAG 
GATGCACTTG CAGCCTTGGA AACTCCAGGA CGTCCCAGCC AACAGAAAAG GAAACTGAGT 
ACGCCACTCT CAGAAGTTAT TGTCAAAAAC TTGCAACTTG CTTTGGCAAA TAGCTCTCGA 
AATGCTGTCG CTCTTTCTGC CAGCCCTCAG CTGAAAGAGG CCCAGTCAGA GAAGGAAGAA 
GCCCCAAAGC CACTTCACAA AGTAGTGGTA TGTGTTAGTA AAAAACTCGG TAAAAAGCAG 
AGTGAACTAA ATGGGATCGC AGCCTCTCTA GGAGCAGATT ACAGGTGGAG TTTTGATGAA 
ACAGTGACTC ATTTCATCTA TCAAGGGCGG CCAAATGACA CTAATCGGGA GTATAAATCT 
GTAAAAGAAA GAGGAGTACA CATTGTTTCC GAGCACTGGC TTTTAGATTG TGCCCAAGAG 
TGTAAACATC TTCCTGAATC TCTTTATCCG CATACTTATA ATCCCAAAAT GAGCTTGGAT 
ATCAGTGCAG TGCAAGATGG CCGACTCTGT AATAGTCGAC TACTCTCAGC TGTGTCTGCA 
ACAAAGGATG ATGAGCCAGA TCCTTTGATT TTAGAAGAAA ATGATGTAGA CAATATGGCC 
ACCAATAATA AAGAGTCAGC ACCATCAAAT GGAAGTGGAA AGAATGACTC TAAAGGAGTT 
CTGACACAGA CCTTAGAGAT GAGAGAGAAC TTTCAGAAGC AGTTACAGGA GATAATGTCT 
GCAACATCAA TAGTGAAACC CCAAGGGCAG AGGACTTCCC TTTCAAGAAG TGGTTGTAAC 
AGCGCATCTT CAACCCCTGA CAGCACTCGC TCTGCTCGCA GTGGACGAAG TAGAGTCCTA 
GAGGCACTGA GGCAGTCTCG TCAAACAGTA CCTGATGTCA ACACAGAGCC TTCCCAAAAT 
GAACAGATTA TTTGGGATGA CCCTACAGCA AGGGAGGAGA GAGCAAGGCT TGCCAGCAAT 
TTGCAGTGGC CTAGTTGTCC CACACAATAC TCTGAGCTTC AGGTTGACAT TCAAAACTTG 
GAGGATTCTC CTTTTCAAAA GCCTTTACAT GATTCAGAAA TTGCTAAACA GGCTGTCTGT 
GATCCTGGAA ACATACGTGT GACTGAAGCT CCCAAACACC CAATCTCTGA AGAACTGGAA 
ACTCCCATAA AAGATAGCCA CCTGATCCCT ACGCCTCAAG CCCCCAGTAT TGCCTTTCCA 
CTCGCCAACC CCCCTGTGGC TCCGCACCCT AGAGAAAAGA TTATAATGAT AGAGGAGACT 
CATGAAGAAT TAAAAAAACA GTACATATTT CAGTTATCAT CTCTGAATCC TCAAGAACGT 
ATTGACTATT GTCATCTGAT TGAGAAACTA GGTGGATTGG TGATAGAAAA GCAGTGCTTT 
GATCCCACCT GTACACACAT TGTTGTGGGA CATCCACTTC GAAACGAGAA GTATTTAGCC 
TCAGTGGCAG CTGGGAAGTG GGTGCTTCAT CGCTCCTACC TTGAAGCCTG CAGGACTGCT 
GGACACTTCG TGCAGGAAGA AGACTATGAA TGGGGAAGTA GTTCCATACT TGATGTTTTG 
ACTGGAATCA ATGTACAGCA ACGAAGACTA GCACTTGCAG CAATGAGATG GAGAAAAAAA 
ATCCAGCAAA GACAAGAATC TGGCATTGTT GAGGGAGCAT TTAGTGGGTG GAAGGTTATT 
TTACATGTGG ATCAGTCTCG AGAAGCAGGC TTCAAACGCC TTCTTCAGTC AGGAGGAGCA 
AAGGTGCTAC CTGGTCATTC TGTACCTTTA TTTAAAGAGG CCACACATCT TTTTTCTGAC 
TTGAATAAAC TGAAACCAGA TGACTCAGGA GTTAATATAG CAGAAGCTGC TGCCCAGAAC 
GTGTACTGCT TGAGAACAGA ATACATTGCT GATTATCTCA TGCAGGAATC ACCTCCTCAT 
GTAGAAAATT ACTGTCTACC AGAAGCTATT TCATTTATTC AGAATAATAA GGAACTTGGG 
ACTGGATTAT CACAAAAGAG GAAAGCTCCT ACAGAAAAAA ATAAAATCAA ACGACCTAGA 
GTACACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_516761.4
CDS	159..4727
Translation	MSRNDKEPFFVKFLKSSDNSKCFFKALESIKEFQSEEYLQIITEEEALKIKENDRSLYICDPFSGVVFDHLKKLGCRIVGPQVVIFCMHHQRCVPRAEHPVYNMVMSDVTISCTSLEKEKREEVHKYVQMMGGRVYRDLNVSVTHLIAGEVGSKKYLVAANLKKPILLPSWIKTLWEKSQEKKITRYTDINMEDFKCPIFLGCIICVTGLCGLDRKEVQQLTVKHGGQYMGQLKMNECTHLIVQEPKGQKYECAKRWNVHCVTTQWFFDSIEKGFCQDESIYKTEPRPEAKTMPNSSTPTSQINTIDSRTLSDVSNISNINASCVSESICNSLNSKLEPTLENLENLDVSAFQAPEDLLDGCRIYLCGFSGRKLDKLRRLINSGGGVRFNQLNEDVTHVIVGDYDDELKQFWNKSAHRPHVVGAKWLLECFSKGYMLSEEPYIHANYQPVEIPVSHQPESKAALLKKKNSSFSKKDFAPSEKHEQADEDLLSQYENDSSTVVEAKTSEARPFNDSTHAEPLNDSTHISLQEENQSSVSHCVPDVSTITEEGLFSQKSFLVLGFSNENESNIANIIKENAGKIMSLLSRTVADYAVVPLLGCEVEATVGEVVTNTWLVTCIDYQTLFDPKSNPLFTPVPVMTGMTPLEDCVISFSQCAGAEKESLTFLANLLGASVQEYFVRKSNAKKGMFASTHLILKERGGSKYEAAKKWNLPAVTIAWLLETARTGKRADESHFLIENSSKEERSLETEITNGINLNSDTAEHPGTRLQTHRKTVVTPLDMNRFQSKAFRAVVSQHARQVAASPAVGQPLQKEPSLHLDTPSKFLSKDKLFKPSFDVKDALAALETPGRPSQQKRKLSTPLSEVIVKNLQLALANSSRNAVALSASPQLKEAQSEKEEAPKPLHKVVVCVSKKLGKKQSELNGIAASLGADYRWSFDETVTHFIYQGRPNDTNREYKSVKERGVHIVSEHWLLDCAQECKHLPESLYPHTYNPKMSLDISAVQDGRLCNSRLLSAVSATKDDEPDPLILEENDVDNMATNNKESAPSNGSGKNDSKGVLTQTLEMRENFQKQLQEIMSATSIVKPQGQRTSLSRSGCNSASSTPDSTRSARSGRSRVLEALRQSRQTVPDVNTEPSQNEQIIWDDPTAREERARLASNLQWPSCPTQYSELQVDIQNLEDSPFQKPLHDSEIAKQAVCDPGNIRVTEAPKHPISEELETPIKDSHLIPTPQAPSIAFPLANPPVAPHPREKIIMIEETHEELKKQYIFQLSSLNPQERIDYCHLIEKLGGLVIEKQCFDPTCTHIVVGHPLRNEKYLASVAAGKWVLHRSYLEACRTAGHFVQEEDYEWGSSSILDVLTGINVQQRRLALAAMRWRKKIQQRQESGIVEGAFSGWKVILHVDQSREAGFKRLLQSGGAKVLPGHSVPLFKEATHLFSDLNKLKPDDSGVNIAEAAAQNVYCLRTEYIADYLMQESPPHVENYCLPEAISFIQNNKELGTGLSQKRKAPTEKNKIKRPRVH

Target ORF information:

RefSeq Version	XM_516761.6
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes topoisomerase (DNA) II binding protein 1 (TOPBP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_516761.6

ORF Insert Sequence:

ATGTCCAGAA ATGACAAAGA ACCGTTTTTT GTGAAGTTTT TAAAGTCTTC AGACAATTCC 
AAATGTTTTT TTAAAGCTCT CGAGTCCATA AAAGAATTCC AATCAGAAGA ATATCTTCAG 
ATTATTACAG AAGAAGAGGC ATTGAAGATA AAGGAGAATG ATAGATCACT TTATATCTGT 
GACCCTTTTA GTGGCGTTGT CTTTGATCAC CTCAAAAAGC TTGGCTGCAG AATTGTTGGT 
CCTCAAGTAG TCATATTTTG TATGCACCAC CAGCGATGTG TCCCAAGAGC CGAACATCCA 
GTTTATAATA TGGTTATGTC TGATGTAACC ATATCTTGTA CAAGTCTGGA AAAAGAAAAA 
AGGGAAGAAG TTCATAAATA TGTACAAATG ATGGGCGGAC GAGTATACAG AGACCTTAAT 
GTATCAGTAA CTCACCTTAT TGCAGGAGAA GTTGGTAGCA AAAAATATTT AGTTGCTGCA 
AACCTGAAGA AACCTATTTT GCTTCCCTCT TGGATAAAAA CACTTTGGGA GAAGTCACAA 
GAGAAAAAAA TAACTAGATA TACTGATATA AACATGGAAG ATTTCAAGTG TCCTATTTTT 
CTTGGTTGCA TAATCTGTGT GACTGGCTTA TGTGGCTTAG ACAGGAAAGA AGTTCAGCAA 
CTCACAGTTA AGCATGGAGG TCAATACATG GGACAGTTGA AAATGAATGA ATGTACACAC 
CTCATTGTGC AAGAACCAAA AGGTCAGAAG TATGAGTGTG CCAAGAGATG GAATGTACAC 
TGTGTGACCA CACAGTGGTT TTTTGACAGT ATTGAGAAAG GTTTTTGTCA GGATGAATCC 
ATATACAAGA CAGAACCTAG ACCAGAAGCA AAGACTATGC CCAATTCTTC AACTCCTACC 
AGCCAGATCA ACACAATTGA TAGTCGTACT CTTTCAGATG TCAGCAATAT TTCCAACATA 
AATGCAAGTT GCGTAAGTGA ATCAATATGT AATTCACTTA ACAGCAAACT GGAGCCTACA 
CTTGAAAATC TAGAAAATCT GGATGTCAGT GCATTTCAAG CACCTGAAGA TTTATTAGAT 
GGTTGTCGGA TATATCTTTG CGGTTTTAGT GGCAGAAAGC TAGATAAACT GAGAAGACTT 
ATTAACAGTG GAGGTGGAGT TCGTTTTAAC CAGCTAAATG AAGATGTAAC TCATGTTATT 
GTGGGAGATT ATGATGATGA ATTGAAGCAG TTTTGGAATA AATCAGCCCA CAGGCCTCAT 
GTAGTGGGAG CAAAGTGGTT GCTAGAGTGT TTCAGTAAAG GTTATATGCT TTCTGAAGAA 
CCATATATCC ATGCTAATTA CCAGCCAGTG GAAATTCCAG TTTCACATCA GCCTGAAAGT 
AAAGCAGCTC TTTTAAAAAA GAAGAACAGC AGCTTCTCTA AGAAAGACTT TGCTCCTAGT 
GAAAAGCATG AGCAAGCTGA TGAAGATCTG CTCTCTCAAT ATGAAAATGA TAGCTCCACA 
GTAGTTGAGG CTAAGACGTC TGAAGCCAGG CCCTTTAATG ATTCTACTCA TGCTGAGCCC 
TTGAATGATT CTACTCACAT TTCTTTGCAA GAAGAAAACC AGTCTTCTGT CAGTCATTGT 
GTCCCTGATG TTTCTACAAT TACTGAAGAA GGCTTATTTA GCCAAAAGAG TTTCCTTGTT 
TTGGGTTTTA GTAATGAAAA TGAATCTAAC ATCGCAAACA TCATAAAAGA AAATGCTGGG 
AAAATCATGT CCCTTCTGAG CAGAACTGTT GCGGATTATG CTGTGGTTCC TCTGCTGGGG 
TGTGAAGTGG AAGCCACTGT GGGAGAAGTT GTTACAAATA CATGGCTGGT TACTTGCATA 
GACTATCAGA CTTTGTTTGA TCCAAAGTCG AATCCTCTCT TCACACCAGT CCCAGTAATG 
ACAGGAATGA CTCCTTTAGA GGATTGTGTT ATTTCATTTA GCCAGTGTGC TGGAGCAGAA 
AAAGAGTCTT TAACATTCCT AGCAAACCTC CTTGGAGCAA GTGTTCAAGA ATACTTTGTT 
CGCAAATCCA ATGCAAAGAA AGGCATGTTT GCCAGTACTC ATCTTATACT GAAAGAACGT 
GGTGGCTCTA AATATGAAGC TGCAAAGAAG TGGAATTTAC CTGCAGTTAC TATAGCTTGG 
CTGTTGGAGA CTGCTAGAAC GGGAAAGAGA GCAGACGAAA GCCATTTTCT GATTGAAAAT 
TCATCTAAAG AAGAACGAAG TTTGGAAACA GAAATAACAA ATGGAATCAA TCTAAATTCA 
GATACTGCAG AGCATCCTGG CACACGCCTG CAAACTCACA GAAAAACCGT CGTTACACCT 
TTAGATATGA ACCGCTTTCA GAGTAAAGCT TTCCGTGCTG TGGTCTCACA ACATGCCAGA 
CAGGTCGCAG CCTCCCCAGC AGTAGGACAA CCACTTCAGA AGGAGCCCTC GTTACACCTG 
GATACACCAT CAAAATTCCT GTCCAAGGAC AAACTCTTCA AGCCTTCCTT TGATGTGAAG 
GATGCACTTG CAGCCTTGGA AACTCCAGGA CGTCCCAGCC AACAGAAAAG GAAACTGAGT 
ACGCCACTCT CAGAAGTTAT TGTCAAAAAC TTGCAACTTG CTTTGGCAAA TAGCTCTCGA 
AATGCTGTCG CTCTTTCTGC CAGCCCTCAG CTGAAAGAGG CCCAGTCAGA GAAGGAAGAA 
GCCCCAAAGC CACTTCACAA AGTAGTGGTA TGTGTTAGTA AAAAACTCGG TAAAAAGCAG 
AGTGAACTAA ATGGGATCGC AGCCTCTCTA GGAGCAGATT ACAGGTGGAG TTTTGATGAA 
ACAGTGACTC ATTTCATCTA TCAAGGGCGG CCAAATGACA CTAATCGGGA GTATAAATCT 
GTAAAAGAAA GAGGAGTACA CATTGTTTCC GAGCACTGGC TTTTAGATTG TGCCCAAGAG 
TGTAAACATC TTCCTGAATC TCTTTATCCG CATACTTATA ATCCCAAAAT GAGCTTGGAT 
ATCAGTGCAG TGCAAGATGG CCGACTCTGT AATAGTCGAC TACTCTCAGC TGTGTCTGCA 
ACAAAGGATG ATGAGCCAGA TCCTTTGATT TTAGAAGAAA ATGATGTAGA CAATATGGCC 
ACCAATAATA AAGAGTCAGC ACCATCAAAT GGAAGTGGAA AGAATGACTC TAAAGGAGTT 
CTGACACAGA CCTTAGAGAT GAGAGAGAAC TTTCAGAAGC AGTTACAGGA GATAATGTCT 
GCAACATCAA TAGTGAAACC CCAAGGGCAG AGGACTTCCC TTTCAAGAAG TGGTTGTAAC 
AGCGCATCTT CAACCCCTGA CAGCACTCGC TCTGCTCGCA GTGGACGAAG TAGAGTCCTA 
GAGGCACTGA GGCAGTCTCG TCAAACAGTA CCTGATGTCA ACACAGAGCC TTCCCAAAAT 
GAACAGATTA TTTGGGATGA CCCTACAGCA AGGGAGGAGA GAGCAAGGCT TGCCAGCAAT 
TTGCAGTGGC CTAGTTGTCC CACACAATAC TCTGAGCTTC AGGTTGACAT TCAAAACTTG 
GAGGATTCTC CTTTTCAAAA GCCTTTACAT GATTCAGAAA TTGCTAAACA GGCTGTCTGT 
GATCCTGGAA ACATACGTGT GACTGAAGCT CCCAAACACC CAATCTCTGA AGAACTGGAA 
ACTCCCATAA AAGATAGCCA CCTGATCCCT ACGCCTCAAG CCCCCAGTAT TGCCTTTCCA 
CTCGCCAACC CCCCTGTGGC TCCGCACCCT AGAGAAAAGA TTATAATGAT AGAGGAGACT 
CATGAAGAAT TAAAAAAACA GTACATATTT CAGTTATCAT CTCTGAATCC TCAAGAACGT 
ATTGACTATT GTCATCTGAT TGAGAAACTA GGTGGATTGG TGATAGAAAA GCAGTGCTTT 
GATCCCACCT GTACACACAT TGTTGTGGGA CATCCACTTC GAAACGAGAA GTATTTAGCC 
TCAGTGGCAG CTGGGAAGTG GGTGCTTCAT CGCTCCTACC TTGAAGCCTG CAGGACTGCT 
GGACACTTCG TGCAGGAAGA AGACTATGAA TGGGGAAGTA GTTCCATACT TGATGTTTTG 
ACTGGAATCA ATGTACAGCA ACGAAGACTA GCACTTGCAG CAATGAGATG GAGAAAAAAA 
ATCCAGCAAA GACAAGAATC TGGCATTGTT GAGGGAGCAT TTAGTGGGTG GAAGGTTATT 
TTACATGTGG ATCAGTCTCG AGAAGCAGGC TTCAAACGCC TTCTTCAGTC AGGAGGAGCA 
AAGGTGCTAC CTGGTCATTC TGTACCTTTA TTTAAAGAGG CCACACATCT TTTTTCTGAC 
TTGAATAAAC TGAAACCAGA TGACTCAGGA GTTAATATAG CAGAAGCTGC TGCCCAGAAC 
GTGTACTGCT TGAGAACAGA ATACATTGCT GATTATCTCA TGCAGGAATC ACCTCCTCAT 
GTAGAAAATT ACTGTCTACC AGAAGCTATT TCATTTATTC AGAATAATAA GGAACTTGGG 
ACTGGATTAT CACAAAAGAG GAAAGCTCCT ACAGAAAAAA ATAAAATCAA ACGACCTAGA 
GTACACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOPBP1 ( XM_009446506.2 ) cDNA ORF clone, Pan troglodytes(chimpanzee) -> XP_009444781.2 Pan troglodytes topoisomerase (DNA) II binding protein 1 (TOPBP1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OPc82705
Clone ID Related Accession (Same CDS sequence)	XM_009446506.2
Accession Version	XM_009446506.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-01
Organism	Pan troglodytes(chimpanzee)
Product	DNA topoisomerase 2-binding protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006490.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 2, 2016 this sequence version replaced XM_009446506.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Pan troglodytes Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAGAA ATGACAAAGA ACCGTTTTTT GTGAAGTTTT TAAAGTCTTC AGACAATTCC 
AAATGTTTTT TTAAAGCTCT CGAGTCCATA AAAGAATTCC AATCAGAAGA ATATCTTCAG 
ATTATTACAG AAGAAGAGGC ATTGAAGATA AAGGAGAATG ATAGATCACT TTATATCTGT 
GACCCTTTTA GTGGCGTTGT CTTTGATCAC CTCAAAAAGC TTGGCTGCAG AATTGTTGGT 
CCTCAAGTAG TCATATTTTG TATGCACCAC CAGCGATGTG TCCCAAGAGC CGAACATCCA 
GTTTATAATA TGGTTATGTC TGATGTAACC ATATCTTGTA CAAGTCTGGA AAAAGAAAAA 
AGGGAAGAAG TTCATAAATA TGTACAAATG ATGGGCGGAC GAGTATACAG AGACCTTAAT 
GTATCAGTAA CTCACCTTAT TGCAGGAGAA GTTGGTAGCA AAAAATATTT AGTTGCTGCA 
AACCTGAAGA AACCTATTTT GCTTCCCTCT TGGATAAAAA CACTTTGGGA GAAGTCACAA 
GAGAAAAAAA TAACTAGATA TACTGATATA AACATGGAAG ATTTCAAGTG TCCTATTTTT 
CTTGGTTGCA TAATCTGTGT GACTGGCTTA TGTGGCTTAG ACAGGAAAGA AGTTCAGCAA 
CTCACAGTTA AGCATGGAGG TCAATACATG GGACAGTTGA AAATGAATGA ATGTACACAC 
CTCATTGTGC AAGAACCAAA AGGTCAGAAG TATGAGTGTG CCAAGAGATG GAATGTACAC 
TGTGTGACCA CACAGTGGTT TTTTGACAGT ATTGAGAAAG GTTTTTGTCA GGATGAATCC 
ATATACAAGA CAGAACCTAG ACCAGAAGCA AAGACTATGC CCAATTCTTC AACTCCTACC 
AGCCAGATCA ACACAATTGA TAATGTCAGC AATATTTCCA ACATAAATGC AAGTTGCGTA 
AGTGAATCAA TATGTAATTC ACTTAACAGC AAACTGGAGC CTACACTTGA AAATCTAGAA 
AATCTGGATG TCAGTGCATT TCAAGCACCT GAAGATTTAT TAGATGGTTG TCGGATATAT 
CTTTGCGGTT TTAGTGGCAG AAAGCTAGAT AAACTGAGAA GACTTATTAA CAGTGGAGGT 
GGAGTTCGTT TTAACCAGCT AAATGAAGAT GTAACTCATG TTATTGTGGG AGATTATGAT 
GATGAATTGA AGCAGTTTTG GAATAAATCA GCCCACAGGC CTCATGTAGT GGGAGCAAAG 
TGGTTGCTAG AGTGTTTCAG TAAAGGTTAT ATGCTTTCTG AAGAACCATA TATCCATGCT 
AATTACCAGC CAGTGGAAAT TCCAGTTTCA CATCAGCCTG AAAGTAAAGC AGCTCTTTTA 
AAAAAGAAGA ACAGCAGCTT CTCTAAGAAA GACTTTGCTC CTAGTGAAAA GCATGAGCAA 
GCTGATGAAG ATCTGCTCTC TCAATATGAA AATGATAGCT CCACAGTAGT TGAGGCTAAG 
ACGTCTGAAG CCAGGCCCTT TAATGATTCT ACTCATGCTG AGCCCTTGAA TGATTCTACT 
CACATTTCTT TGCAAGAAGA AAACCAGTCT TCTGTCAGTC ATTGTGTCCC TGATGTTTCT 
ACAATTACTG AAGAAGGCTT ATTTAGCCAA AAGAGTTTCC TTGTTTTGGG TTTTAGTAAT 
GAAAATGAAT CTAACATCGC AAACATCATA AAAGAAAATG CTGGGAAAAT CATGTCCCTT 
CTGAGCAGAA CTGTTGCGGA TTATGCTGTG GTTCCTCTGC TGGGGTGTGA AGTGGAAGCC 
ACTGTGGGAG AAGTTGTTAC AAATACATGG CTGGTTACTT GCATAGACTA TCAGACTTTG 
TTTGATCCAA AGTCGAATCC TCTCTTCACA CCAGTCCCAG TAATGACAGG AATGACTCCT 
TTAGAGGATT GTGTTATTTC ATTTAGCCAG TGTGCTGGAG CAGAAAAAGA GTCTTTAACA 
TTCCTAGCAA ACCTCCTTGG AGCAAGTGTT CAAGAATACT TTGTTCGCAA ATCCAATGCA 
AAGAAAGGCA TGTTTGCCAG TACTCATCTT ATACTGAAAG AACGTGGTGG CTCTAAATAT 
GAAGCTGCAA AGAAGTGGAA TTTACCTGCA GTTACTATAG CTTGGCTGTT GGAGACTGCT 
AGAACGGGAA AGAGAGCAGA CGAAAGCCAT TTTCTGATTG AAAATTCATC TAAAGAAGAA 
CGAAGTTTGG AAACAGAAAT AACAAATGGA ATCAATCTAA ATTCAGATAC TGCAGAGCAT 
CCTGGCACAC GCCTGCAAAC TCACAGAAAA ACCGTCGTTA CACCTTTAGA TATGAACCGC 
TTTCAGAGTA AAGCTTTCCG TGCTGTGGTC TCACAACATG CCAGACAGGT CGCAGCCTCC 
CCAGCAGTAG GACAACCACT TCAGAAGGAG CCCTCGTTAC ACCTGGATAC ACCATCAAAA 
TTCCTGTCCA AGGACAAACT CTTCAAGCCT TCCTTTGATG TGAAGGATGC ACTTGCAGCC 
TTGGAAACTC CAGGACGTCC CAGCCAACAG AAAAGGAAAC TGAGTACGCC ACTCTCAGAA 
GTTATTGTCA AAAACTTGCA ACTTGCTTTG GCAAATAGCT CTCGAAATGC TGTCGCTCTT 
TCTGCCAGCC CTCAGCTGAA AGAGGCCCAG TCAGAGAAGG AAGAAGCCCC AAAGCCACTT 
CACAAAGTAG TGGTATGTGT TAGTAAAAAA CTCGGTAAAA AGCAGAGTGA ACTAAATGGG 
ATCGCAGCCT CTCTAGGAGC AGATTACAGG TGGAGTTTTG ATGAAACAGT GACTCATTTC 
ATCTATCAAG GGCGGCCAAA TGACACTAAT CGGGAGTATA AATCTGTAAA AGAAAGAGGA 
GTACACATTG TTTCCGAGCA CTGGCTTTTA GATTGTGCCC AAGAGTGTAA ACATCTTCCT 
GAATCTCTTT ATCCGCATAC TTATAATCCC AAAATGAGCT TGGATATCAG TGCAGTGCAA 
GATGGCCGAC TCTGTAATAG TCGACTACTC TCAGCTGTGT CTGCAACAAA GGATGATGAG 
CCAGATCCTT TGATTTTAGA AGAAAATGAT GTAGACAATA TGGCCACCAA TAATAAAGAG 
TCAGCACCAT CAAATGGAAG TGGAAAGAAT GACTCTAAAG GAGTTCTGAC ACAGACCTTA 
GAGATGAGAG AGAACTTTCA GAAGCAGTTA CAGGAGATAA TGTCTGCAAC ATCAATAGTG 
AAACCCCAAG GGCAGAGGAC TTCCCTTTCA AGAAGTGGTT GTAACAGCGC ATCTTCAACC 
CCTGACAGCA CTCGCTCTGC TCGCAGTGGA CGAAGTAGAG TCCTAGAGGC ACTGAGGCAG 
TCTCGTCAAA CAGTACCTGA TGTCAACACA GAGCCTTCCC AAAATGAACA GATTATTTGG 
GATGACCCTA CAGCAAGGGA GGAGAGAGCA AGGCTTGCCA GCAATTTGCA GTGGCCTAGT 
TGTCCCACAC AATACTCTGA GCTTCAGGTT GACATTCAAA ACTTGGAGGA TTCTCCTTTT 
CAAAAGCCTT TACATGATTC AGAAATTGCT AAACAGGCTG TCTGTGATCC TGGAAACATA 
CGTGTGACTG AAGCTCCCAA ACACCCAATC TCTGAAGAAC TGGAAACTCC CATAAAAGAT 
AGCCACCTGA TCCCTACGCC TCAAGCCCCC AGTATTGCCT TTCCACTCGC CAACCCCCCT 
GTGGCTCCGC ACCCTAGAGA AAAGATTATA ATGATAGAGG AGACTCATGA AGAATTAAAA 
AAACAGTACA TATTTCAGTT ATCATCTCTG AATCCTCAAG AACGTATTGA CTATTGTCAT 
CTGATTGAGA AACTAGGTGG ATTGGTGATA GAAAAGCAGT GCTTTGATCC CACCTGTACA 
CACATTGTTG TGGGACATCC ACTTCGAAAC GAGAAGTATT TAGCCTCAGT GGCAGCTGGG 
AAGTGGGTGC TTCATCGCTC CTACCTTGAA GCCTGCAGGA CTGCTGGACA CTTCGTGCAG 
GAAGAAGACT ATGAATGGGG AAGTAGTTCC ATACTTGATG TTTTGACTGG AATCAATGTA 
CAGCAACGAA GACTAGCACT TGCAGCAATG AGATGGAGAA AAAAAATCCA GCAAAGACAA 
GAATCTGGCA TTGTTGAGGG AGCATTTAGT GGGTGGAAGG TTATTTTACA TGTGGATCAG 
TCTCGAGAAG CAGGCTTCAA ACGCCTTCTT CAGTCAGGAG GAGCAAAGGT GCTACCTGGT 
CATTCTGTAC CTTTATTTAA AGAGGCCACA CATCTTTTTT CTGACTTGAA TAAACTGAAA 
CCAGATGACT CAGGAGTTAA TATAGCAGAA GCTGCTGCCC AGAACGTGTA CTGCTTGAGA 
ACAGAATACA TTGCTGATTA TCTCATGCAG GAATCACCTC CTCATGTAGA AAATTACTGT 
CTACCAGAAG CTATTTCATT TATTCAGAAT AATAAGGAAC TTGGGACTGG ATTATCACAA 
AAGAGGAAAG CTCCTACAGA AAAAAATAAA ATCAAACGAC CTAGAGTACA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_009444781.2
CDS	159..4712
Translation	MSRNDKEPFFVKFLKSSDNSKCFFKALESIKEFQSEEYLQIITEEEALKIKENDRSLYICDPFSGVVFDHLKKLGCRIVGPQVVIFCMHHQRCVPRAEHPVYNMVMSDVTISCTSLEKEKREEVHKYVQMMGGRVYRDLNVSVTHLIAGEVGSKKYLVAANLKKPILLPSWIKTLWEKSQEKKITRYTDINMEDFKCPIFLGCIICVTGLCGLDRKEVQQLTVKHGGQYMGQLKMNECTHLIVQEPKGQKYECAKRWNVHCVTTQWFFDSIEKGFCQDESIYKTEPRPEAKTMPNSSTPTSQINTIDNVSNISNINASCVSESICNSLNSKLEPTLENLENLDVSAFQAPEDLLDGCRIYLCGFSGRKLDKLRRLINSGGGVRFNQLNEDVTHVIVGDYDDELKQFWNKSAHRPHVVGAKWLLECFSKGYMLSEEPYIHANYQPVEIPVSHQPESKAALLKKKNSSFSKKDFAPSEKHEQADEDLLSQYENDSSTVVEAKTSEARPFNDSTHAEPLNDSTHISLQEENQSSVSHCVPDVSTITEEGLFSQKSFLVLGFSNENESNIANIIKENAGKIMSLLSRTVADYAVVPLLGCEVEATVGEVVTNTWLVTCIDYQTLFDPKSNPLFTPVPVMTGMTPLEDCVISFSQCAGAEKESLTFLANLLGASVQEYFVRKSNAKKGMFASTHLILKERGGSKYEAAKKWNLPAVTIAWLLETARTGKRADESHFLIENSSKEERSLETEITNGINLNSDTAEHPGTRLQTHRKTVVTPLDMNRFQSKAFRAVVSQHARQVAASPAVGQPLQKEPSLHLDTPSKFLSKDKLFKPSFDVKDALAALETPGRPSQQKRKLSTPLSEVIVKNLQLALANSSRNAVALSASPQLKEAQSEKEEAPKPLHKVVVCVSKKLGKKQSELNGIAASLGADYRWSFDETVTHFIYQGRPNDTNREYKSVKERGVHIVSEHWLLDCAQECKHLPESLYPHTYNPKMSLDISAVQDGRLCNSRLLSAVSATKDDEPDPLILEENDVDNMATNNKESAPSNGSGKNDSKGVLTQTLEMRENFQKQLQEIMSATSIVKPQGQRTSLSRSGCNSASSTPDSTRSARSGRSRVLEALRQSRQTVPDVNTEPSQNEQIIWDDPTAREERARLASNLQWPSCPTQYSELQVDIQNLEDSPFQKPLHDSEIAKQAVCDPGNIRVTEAPKHPISEELETPIKDSHLIPTPQAPSIAFPLANPPVAPHPREKIIMIEETHEELKKQYIFQLSSLNPQERIDYCHLIEKLGGLVIEKQCFDPTCTHIVVGHPLRNEKYLASVAAGKWVLHRSYLEACRTAGHFVQEEDYEWGSSSILDVLTGINVQQRRLALAAMRWRKKIQQRQESGIVEGAFSGWKVILHVDQSREAGFKRLLQSGGAKVLPGHSVPLFKEATHLFSDLNKLKPDDSGVNIAEAAAQNVYCLRTEYIADYLMQESPPHVENYCLPEAISFIQNNKELGTGLSQKRKAPTEKNKIKRPRVH

Target ORF information:

RefSeq Version	XM_009446506.2
Organism	Pan troglodytes(chimpanzee)
Definition	Pan troglodytes topoisomerase (DNA) II binding protein 1 (TOPBP1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_009446506.2

ORF Insert Sequence:

ATGTCCAGAA ATGACAAAGA ACCGTTTTTT GTGAAGTTTT TAAAGTCTTC AGACAATTCC 
AAATGTTTTT TTAAAGCTCT CGAGTCCATA AAAGAATTCC AATCAGAAGA ATATCTTCAG 
ATTATTACAG AAGAAGAGGC ATTGAAGATA AAGGAGAATG ATAGATCACT TTATATCTGT 
GACCCTTTTA GTGGCGTTGT CTTTGATCAC CTCAAAAAGC TTGGCTGCAG AATTGTTGGT 
CCTCAAGTAG TCATATTTTG TATGCACCAC CAGCGATGTG TCCCAAGAGC CGAACATCCA 
GTTTATAATA TGGTTATGTC TGATGTAACC ATATCTTGTA CAAGTCTGGA AAAAGAAAAA 
AGGGAAGAAG TTCATAAATA TGTACAAATG ATGGGCGGAC GAGTATACAG AGACCTTAAT 
GTATCAGTAA CTCACCTTAT TGCAGGAGAA GTTGGTAGCA AAAAATATTT AGTTGCTGCA 
AACCTGAAGA AACCTATTTT GCTTCCCTCT TGGATAAAAA CACTTTGGGA GAAGTCACAA 
GAGAAAAAAA TAACTAGATA TACTGATATA AACATGGAAG ATTTCAAGTG TCCTATTTTT 
CTTGGTTGCA TAATCTGTGT GACTGGCTTA TGTGGCTTAG ACAGGAAAGA AGTTCAGCAA 
CTCACAGTTA AGCATGGAGG TCAATACATG GGACAGTTGA AAATGAATGA ATGTACACAC 
CTCATTGTGC AAGAACCAAA AGGTCAGAAG TATGAGTGTG CCAAGAGATG GAATGTACAC 
TGTGTGACCA CACAGTGGTT TTTTGACAGT ATTGAGAAAG GTTTTTGTCA GGATGAATCC 
ATATACAAGA CAGAACCTAG ACCAGAAGCA AAGACTATGC CCAATTCTTC AACTCCTACC 
AGCCAGATCA ACACAATTGA TAATGTCAGC AATATTTCCA ACATAAATGC AAGTTGCGTA 
AGTGAATCAA TATGTAATTC ACTTAACAGC AAACTGGAGC CTACACTTGA AAATCTAGAA 
AATCTGGATG TCAGTGCATT TCAAGCACCT GAAGATTTAT TAGATGGTTG TCGGATATAT 
CTTTGCGGTT TTAGTGGCAG AAAGCTAGAT AAACTGAGAA GACTTATTAA CAGTGGAGGT 
GGAGTTCGTT TTAACCAGCT AAATGAAGAT GTAACTCATG TTATTGTGGG AGATTATGAT 
GATGAATTGA AGCAGTTTTG GAATAAATCA GCCCACAGGC CTCATGTAGT GGGAGCAAAG 
TGGTTGCTAG AGTGTTTCAG TAAAGGTTAT ATGCTTTCTG AAGAACCATA TATCCATGCT 
AATTACCAGC CAGTGGAAAT TCCAGTTTCA CATCAGCCTG AAAGTAAAGC AGCTCTTTTA 
AAAAAGAAGA ACAGCAGCTT CTCTAAGAAA GACTTTGCTC CTAGTGAAAA GCATGAGCAA 
GCTGATGAAG ATCTGCTCTC TCAATATGAA AATGATAGCT CCACAGTAGT TGAGGCTAAG 
ACGTCTGAAG CCAGGCCCTT TAATGATTCT ACTCATGCTG AGCCCTTGAA TGATTCTACT 
CACATTTCTT TGCAAGAAGA AAACCAGTCT TCTGTCAGTC ATTGTGTCCC TGATGTTTCT 
ACAATTACTG AAGAAGGCTT ATTTAGCCAA AAGAGTTTCC TTGTTTTGGG TTTTAGTAAT 
GAAAATGAAT CTAACATCGC AAACATCATA AAAGAAAATG CTGGGAAAAT CATGTCCCTT 
CTGAGCAGAA CTGTTGCGGA TTATGCTGTG GTTCCTCTGC TGGGGTGTGA AGTGGAAGCC 
ACTGTGGGAG AAGTTGTTAC AAATACATGG CTGGTTACTT GCATAGACTA TCAGACTTTG 
TTTGATCCAA AGTCGAATCC TCTCTTCACA CCAGTCCCAG TAATGACAGG AATGACTCCT 
TTAGAGGATT GTGTTATTTC ATTTAGCCAG TGTGCTGGAG CAGAAAAAGA GTCTTTAACA 
TTCCTAGCAA ACCTCCTTGG AGCAAGTGTT CAAGAATACT TTGTTCGCAA ATCCAATGCA 
AAGAAAGGCA TGTTTGCCAG TACTCATCTT ATACTGAAAG AACGTGGTGG CTCTAAATAT 
GAAGCTGCAA AGAAGTGGAA TTTACCTGCA GTTACTATAG CTTGGCTGTT GGAGACTGCT 
AGAACGGGAA AGAGAGCAGA CGAAAGCCAT TTTCTGATTG AAAATTCATC TAAAGAAGAA 
CGAAGTTTGG AAACAGAAAT AACAAATGGA ATCAATCTAA ATTCAGATAC TGCAGAGCAT 
CCTGGCACAC GCCTGCAAAC TCACAGAAAA ACCGTCGTTA CACCTTTAGA TATGAACCGC 
TTTCAGAGTA AAGCTTTCCG TGCTGTGGTC TCACAACATG CCAGACAGGT CGCAGCCTCC 
CCAGCAGTAG GACAACCACT TCAGAAGGAG CCCTCGTTAC ACCTGGATAC ACCATCAAAA 
TTCCTGTCCA AGGACAAACT CTTCAAGCCT TCCTTTGATG TGAAGGATGC ACTTGCAGCC 
TTGGAAACTC CAGGACGTCC CAGCCAACAG AAAAGGAAAC TGAGTACGCC ACTCTCAGAA 
GTTATTGTCA AAAACTTGCA ACTTGCTTTG GCAAATAGCT CTCGAAATGC TGTCGCTCTT 
TCTGCCAGCC CTCAGCTGAA AGAGGCCCAG TCAGAGAAGG AAGAAGCCCC AAAGCCACTT 
CACAAAGTAG TGGTATGTGT TAGTAAAAAA CTCGGTAAAA AGCAGAGTGA ACTAAATGGG 
ATCGCAGCCT CTCTAGGAGC AGATTACAGG TGGAGTTTTG ATGAAACAGT GACTCATTTC 
ATCTATCAAG GGCGGCCAAA TGACACTAAT CGGGAGTATA AATCTGTAAA AGAAAGAGGA 
GTACACATTG TTTCCGAGCA CTGGCTTTTA GATTGTGCCC AAGAGTGTAA ACATCTTCCT 
GAATCTCTTT ATCCGCATAC TTATAATCCC AAAATGAGCT TGGATATCAG TGCAGTGCAA 
GATGGCCGAC TCTGTAATAG TCGACTACTC TCAGCTGTGT CTGCAACAAA GGATGATGAG 
CCAGATCCTT TGATTTTAGA AGAAAATGAT GTAGACAATA TGGCCACCAA TAATAAAGAG 
TCAGCACCAT CAAATGGAAG TGGAAAGAAT GACTCTAAAG GAGTTCTGAC ACAGACCTTA 
GAGATGAGAG AGAACTTTCA GAAGCAGTTA CAGGAGATAA TGTCTGCAAC ATCAATAGTG 
AAACCCCAAG GGCAGAGGAC TTCCCTTTCA AGAAGTGGTT GTAACAGCGC ATCTTCAACC 
CCTGACAGCA CTCGCTCTGC TCGCAGTGGA CGAAGTAGAG TCCTAGAGGC ACTGAGGCAG 
TCTCGTCAAA CAGTACCTGA TGTCAACACA GAGCCTTCCC AAAATGAACA GATTATTTGG 
GATGACCCTA CAGCAAGGGA GGAGAGAGCA AGGCTTGCCA GCAATTTGCA GTGGCCTAGT 
TGTCCCACAC AATACTCTGA GCTTCAGGTT GACATTCAAA ACTTGGAGGA TTCTCCTTTT 
CAAAAGCCTT TACATGATTC AGAAATTGCT AAACAGGCTG TCTGTGATCC TGGAAACATA 
CGTGTGACTG AAGCTCCCAA ACACCCAATC TCTGAAGAAC TGGAAACTCC CATAAAAGAT 
AGCCACCTGA TCCCTACGCC TCAAGCCCCC AGTATTGCCT TTCCACTCGC CAACCCCCCT 
GTGGCTCCGC ACCCTAGAGA AAAGATTATA ATGATAGAGG AGACTCATGA AGAATTAAAA 
AAACAGTACA TATTTCAGTT ATCATCTCTG AATCCTCAAG AACGTATTGA CTATTGTCAT 
CTGATTGAGA AACTAGGTGG ATTGGTGATA GAAAAGCAGT GCTTTGATCC CACCTGTACA 
CACATTGTTG TGGGACATCC ACTTCGAAAC GAGAAGTATT TAGCCTCAGT GGCAGCTGGG 
AAGTGGGTGC TTCATCGCTC CTACCTTGAA GCCTGCAGGA CTGCTGGACA CTTCGTGCAG 
GAAGAAGACT ATGAATGGGG AAGTAGTTCC ATACTTGATG TTTTGACTGG AATCAATGTA 
CAGCAACGAA GACTAGCACT TGCAGCAATG AGATGGAGAA AAAAAATCCA GCAAAGACAA 
GAATCTGGCA TTGTTGAGGG AGCATTTAGT GGGTGGAAGG TTATTTTACA TGTGGATCAG 
TCTCGAGAAG CAGGCTTCAA ACGCCTTCTT CAGTCAGGAG GAGCAAAGGT GCTACCTGGT 
CATTCTGTAC CTTTATTTAA AGAGGCCACA CATCTTTTTT CTGACTTGAA TAAACTGAAA 
CCAGATGACT CAGGAGTTAA TATAGCAGAA GCTGCTGCCC AGAACGTGTA CTGCTTGAGA 
ACAGAATACA TTGCTGATTA TCTCATGCAG GAATCACCTC CTCATGTAGA AAATTACTGT 
CTACCAGAAG CTATTTCATT TATTCAGAAT AATAAGGAAC TTGGGACTGG ATTATCACAA 
AAGAGGAAAG CTCCTACAGA AAAAAATAAA ATCAAACGAC CTAGAGTACA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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TOPBP1 cDNA ORF clone, Pan troglodytes(chimpanzee)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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