Gene Symbol | HST2 |
Entrez Gene ID | 856092 |
Full Name | histone deacetylase HST2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » HST2 cDNA ORF clone
Gene Symbol | HST2 |
Entrez Gene ID | 856092 |
Full Name | histone deacetylase HST2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183829.1 | NP_015310.1 | histone deacetylase HST2 |
LOC100425019 | XP_002801273.1 | |
Drosophila melanogaster (fruit fly) | Sirt2 | NP_650880.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002943 | XP_311957.5 |
Schizosaccharomyces pombe (fission yeast) | hst2 | NP_588147.1 |
Pan troglodytes (chimpanzee) | SIRT2 | XP_001168375.1 |
Danio rerio (zebrafish) | sirt2 | NP_955890.1 |
Bos taurus (cattle) | SIRT2 | NP_001107003.1 |
Mus musculus (house mouse) | Sirt2 | NP_071877.3 |
Rattus norvegicus (Norway rat) | Sirt2 | NP_001008369.1 |
Canis lupus familiaris (dog) | SIRT2 | XP_855382.2 |
Kluyveromyces lactis | KLLA0F11033g | XP_455583.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_17827 | XP_003720356.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100489469 | XP_002935827.2 |
Homo sapiens (human) | SIRT2 | NP_036369.2 |
Gallus gallus (chicken) | SIRT2 | NP_001017414.1 |
Saccharomyces cerevisiae (baker's yeast) | HST2 | NP_015310.1 |
Eremothecium gossypii | AGOS_AGL018C | NP_986648.1 |
Neurospora crassa | NCU00523 | XP_963725.2 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
Bussey H, Storms RK, Ahmed A, Albermann K, Allen E, Ansorge W, Araujo R, Aparicio A, Barrell B, Badcock K, Benes V, Botstein D, Bowman S, Br?ckner M, Carpenter J, Cherry JM, Chung E, Churcher C, Coster F, Davis K, Davis RW, Dietrich FS, Delius H, DiPaolo T, Hani J
Nature387(6632 Suppl)103-5(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data show that Sir2, and not Hst2, regulates the acetylation state of H3 lysine 79.
Title: Biotinylation of lysine method identifies acetylated histone H3 lysine 79 in Saccharomyces cerevisiae as a substrate for Sir2.
Specific functions were found for HST2.
Title: Specific functions for the fission yeast Sirtuins Hst2 and Hst4 in gene regulation and retrotransposon silencing.
Here, we show that Hst2 moves between the nucleus and cytoplasm, but is largely cytoplasmic owing to efficient nuclear export.Disruption of Hst2 export shows that nuclear exclusion inhibits the activity of Hst2 as a transcriptional repressor.
Title: Nuclear export modulates the cytoplasmic Sir2 homologue Hst2.
results show that HST2 is responsible for Sir2-independent life-span extension by calorie restriction and that it does so by suppressing rDNA recombination, the same mechanism by which SIR2 extends life span
Title: HST2 mediates SIR2-independent life-span extension by calorie restriction.
The following HST2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HST2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04949 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183829.1 | |
Accession Version | NM_001183829.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1074bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | histone deacetylase HST2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001148). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCTGTTT CTACCGCCTC TACAGAGATG TCGGTTAGGA AGATCGCTGC TCATATGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_015310.1 |
CDS | 1..1074 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183829.1 |
1 | ATGTCTGTTT CTACCGCCTC TACAGAGATG TCGGTTAGGA AGATCGCTGC TCATATGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. |
Life with 6000 genes. |