SIRT2 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	SIRT2
Entrez Gene ID	504463
Full Name	sirtuin 2
General protein information	Preferred Names sirtuin 2 Names NAD-dependent protein deacetylase sirtuin-2 NAD-dependent deacetylase sirtuin-2 sirtuin-like protein 2
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
XM_024978010.1	XP_024833778.1	NAD-dependent protein deacetylase sirtuin-2 isoform X1
NM_001113531.1	NP_001107003.1	NAD-dependent protein deacetylase sirtuin-2

Pathways from BioSystems

Homologies

	LOC100425019	XP_002801273.1
Drosophila melanogaster (fruit fly)	Sirt2	NP_650880.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002943	XP_311957.5
Schizosaccharomyces pombe (fission yeast)	hst2	NP_588147.1
Pan troglodytes (chimpanzee)	SIRT2	XP_001168375.1
Danio rerio (zebrafish)	sirt2	NP_955890.1
Bos taurus (cattle)	SIRT2	NP_001107003.1
Mus musculus (house mouse)	Sirt2	NP_071877.3
Rattus norvegicus (Norway rat)	Sirt2	NP_001008369.1
Canis lupus familiaris (dog)	SIRT2	XP_855382.2
Kluyveromyces lactis	KLLA0F11033g	XP_455583.1
Magnaporthe oryzae (rice blast fungus)	MGG_17827	XP_003720356.1
Xenopus tropicalis (tropical clawed frog)	LOC100489469	XP_002935827.2
Homo sapiens (human)	SIRT2	NP_036369.2
Gallus gallus (chicken)	SIRT2	NP_001017414.1
Saccharomyces cerevisiae (baker's yeast)	HST2	NP_015310.1
Eremothecium gossypii	AGOS_AGL018C	NP_986648.1
Neurospora crassa	NCU00523	XP_963725.2

Gene Ontology
Bibliography

Related articles in PubMed

Haplotype distribution in the class I sirtuin genes and their associations with ultrasound carcass traits in Qinchuan cattle (Bos taurus).
Gui L, Hao R, Zhang Y, Zhao X, Zan L
Molecular and cellular probes29(3)167-71(2015 Jun)

Expression of the SIRT2 gene and its relationship with body size traits in Qinchuan cattle (Bos taurus).
Gui LS, Zhang YR, Liu GY, Zan LS
International journal of molecular sciences16(2)2458-71(2015 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results indicate that the variations in the class I sirtuin genes and their corresponding genotypes may be considered as molecular markers for economic traits in cattle breeding.
Title: Haplotype distribution in the class I sirtuin genes and their associations with ultrasound carcass traits in Qinchuan cattle (Bos taurus).

An association analysis showed that the two loci of SIRT2 were significantly correlated with some body size traits and the H2H2 (-CT-CT-) diplotypes performed better than other combinations.
Title: Expression of the SIRT2 gene and its relationship with body size traits in Qinchuan cattle (Bos taurus).

Data suggest that the silent information regulator 2 (SIRT2) gene may be a candidate gene for marker-assisted selection in the development of breeding programs for Qinchuan cattle.
Title: Association of SIRT2 gene polymorphisms with body measurement and growth traits of Qinchuan cattle.

The following SIRT2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SIRT2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa28603	NM_001113531.1 Latest version!	Bos taurus sirtuin 2 (SIRT2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OBa224841	XM_024978010.1 Latest version!	Bos taurus sirtuin 2 (SIRT2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SIRT2 ( NM_001113531.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001107003.1 Bos taurus sirtuin 2 (SIRT2), mRNA.

Price & Availability↑

CloneID	OBa28603
Clone ID Related Accession (Same CDS sequence)	NM_001113531.1
Accession Version	NM_001113531.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1173bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-15
Organism	Bos taurus(cattle)
Product	NAD-dependent protein deacetylase sirtuin-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EE225228.1, DN532360.1, DN546771.1 and CO876041.1. On Jan 17, 2008 this sequence version replaced XM_580596.3. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN03145412, SAMN03145413 [ECO:0000350] ##Evidence-Data-END##

ATGGCCGATC CGGATCCCTC TGACCCTGAG GAGACCCAGG CAGGGAAGGT GCAGGAGGCT 
CAGGACTCAG ATTCAGACAC TGAGGCAGGA GCCACTGGCG GAGAAGCAGA GATGGACTTC 
CTGCGGAATT TCTTCTCCCA GACTCTGGGC CTGGGCACCC AGAAGGAGCG ACTCCTGGAC 
GAACTAACCC TGGAAGGAGT GAGCCGCTAC ATGCAGAGCG AGCGCTGTCG CAGGGTCATC 
TGTTTGGTGG GAGCTGGAAT CTCCACTTCC GCGGGTATCC CTGACTTTCG GTCCCCAAAC 
ACGGGCCTCT ATGCCAACCT GGAGAAATAC CGTCTTCCCT ACCCGGAGGC CATCTTTGAA 
ATCAGCTACT TCAAGAAACA TCCAGAGCCC TTCTTTGCTC TCGCCAAGGA ACTCTATCCT 
GGGCAGTTCA AGCCGACCAT CTGCCACTAC TTCATCCGCC TGCTGAAGGA AAAAGGACTG 
CTCCTGCGCT GCTACACACA GAACATAGAC ACCCTGGAGC GAGTGGCTGG GCTGGAGCCC 
GAAGACCTGG TGGAGGCCCA CGGCACCTTC TACACGTCCC ACTGCATCAG CTCAGGCTGC 
CGGCAGGAGT ACTCACTAAG CTGGATGAAA GAGAAGATCT TCTCCGAGGT GACTCCCAAG 
TGTGAGAAAT GTCAGAGCGT GGTGAAGCCT GATATCGTGT TCTTCGGCGA GAACCTCCCA 
GCGCGTTTCT TCTCCTGCAT GCAGTCAGAC TTCCTAAAGG TGGACCTCCT TATCATCATG 
GGCACCTCCC TGCAGGTGCA GCCCTTCGCG TCCCTCATCG GCAAGGCGCC CCTGTCGACC 
CCGCGCCTGC TCATCAACAA GGAGAAGACT GGCCAGACTG ACCCTTTCCT CGGGATGATG 
ATGGCCCTCG GAGGAGGCAT GGACTTTGAC TCCAAGAAGG CCTACAGGGA CGTGGCCTGG 
CTGGGCGACT GTGACCAGGG CTGCCTGGCC CTCGCCGACC TCCTTGGATG GAAGAAGGAG 
CTGGAGGACC TTGTTCGGAA GGAGCATGCC AGCATAGATG CCCAGTCGGG GTCGGGGGCC 
TCCAACCCCG CTACTTCAGC TTCCCCCAGG AATTCTCCAC CACCTCCCAC CAAGGAGGAG 
CCCAGGACCA CTGAGGGAGA GAAACCCCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001107003.1
CDS	86..1258
Translation	MADPDPSDPEETQAGKVQEAQDSDSDTEAGATGGEAEMDFLRNFFSQTLGLGTQKERLLDELTLEGVSRYMQSERCRRVICLVGAGISTSAGIPDFRSPNTGLYANLEKYRLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPEDLVEAHGTFYTSHCISSGCRQEYSLSWMKEKIFSEVTPKCEKCQSVVKPDIVFFGENLPARFFSCMQSDFLKVDLLIIMGTSLQVQPFASLIGKAPLSTPRLLINKEKTGQTDPFLGMMMALGGGMDFDSKKAYRDVAWLGDCDQGCLALADLLGWKKELEDLVRKEHASIDAQSGSGASNPATSASPRNSPPPPTKEEPRTTEGEKPQ

Target ORF information:

RefSeq Version	NM_001113531.1
Organism	Bos taurus(cattle)
Definition	Bos taurus sirtuin 2 (SIRT2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001113531.1

ORF Insert Sequence:

ATGGCCGATC CGGATCCCTC TGACCCTGAG GAGACCCAGG CAGGGAAGGT GCAGGAGGCT 
CAGGACTCAG ATTCAGACAC TGAGGCAGGA GCCACTGGCG GAGAAGCAGA GATGGACTTC 
CTGCGGAATT TCTTCTCCCA GACTCTGGGC CTGGGCACCC AGAAGGAGCG ACTCCTGGAC 
GAACTAACCC TGGAAGGAGT GAGCCGCTAC ATGCAGAGCG AGCGCTGTCG CAGGGTCATC 
TGTTTGGTGG GAGCTGGAAT CTCCACTTCC GCGGGTATCC CTGACTTTCG GTCCCCAAAC 
ACGGGCCTCT ATGCCAACCT GGAGAAATAC CGTCTTCCCT ACCCGGAGGC CATCTTTGAA 
ATCAGCTACT TCAAGAAACA TCCAGAGCCC TTCTTTGCTC TCGCCAAGGA ACTCTATCCT 
GGGCAGTTCA AGCCGACCAT CTGCCACTAC TTCATCCGCC TGCTGAAGGA AAAAGGACTG 
CTCCTGCGCT GCTACACACA GAACATAGAC ACCCTGGAGC GAGTGGCTGG GCTGGAGCCC 
GAAGACCTGG TGGAGGCCCA CGGCACCTTC TACACGTCCC ACTGCATCAG CTCAGGCTGC 
CGGCAGGAGT ACTCACTAAG CTGGATGAAA GAGAAGATCT TCTCCGAGGT GACTCCCAAG 
TGTGAGAAAT GTCAGAGCGT GGTGAAGCCT GATATCGTGT TCTTCGGCGA GAACCTCCCA 
GCGCGTTTCT TCTCCTGCAT GCAGTCAGAC TTCCTAAAGG TGGACCTCCT TATCATCATG 
GGCACCTCCC TGCAGGTGCA GCCCTTCGCG TCCCTCATCG GCAAGGCGCC CCTGTCGACC 
CCGCGCCTGC TCATCAACAA GGAGAAGACT GGCCAGACTG ACCCTTTCCT CGGGATGATG 
ATGGCCCTCG GAGGAGGCAT GGACTTTGAC TCCAAGAAGG CCTACAGGGA CGTGGCCTGG 
CTGGGCGACT GTGACCAGGG CTGCCTGGCC CTCGCCGACC TCCTTGGATG GAAGAAGGAG 
CTGGAGGACC TTGTTCGGAA GGAGCATGCC AGCATAGATG CCCAGTCGGG GTCGGGGGCC 
TCCAACCCCG CTACTTCAGC TTCCCCCAGG AATTCTCCAC CACCTCCCAC CAAGGAGGAG 
CCCAGGACCA CTGAGGGAGA GAAACCCCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SIRT2 ( XM_024978010.1 ) cDNA ORF clone, Bos taurus(cattle) -> XP_024833778.1 Bos taurus sirtuin 2 (SIRT2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa224841
Clone ID Related Accession (Same CDS sequence)	XM_024978010.1
Accession Version	XM_024978010.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	NAD-dependent protein deacetylase sirtuin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037345.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACTTCC TGCGGAATTT CTTCTCCCAG ACTCTGGGCC TGGGCACCCA GAAGGAGCGA 
CTCCTGGACG AACTAACCCT GGAAGGAGTG AGCCGCTACA TGCAGAGCGA GCGCTGTCGC 
AGGGTCATCT GTTTGGTGGG AGCTGGAATC TCCACTTCCG CGGGTATCCC TGACTTTCGG 
TCCCCAAACA CGGGCCTCTA TGCCAACCTG GAGAAATACC GTCTTCCCTA CCCGGAGGCC 
ATCTTTGAAA TCAGCTACTT CAAGAAACAT CCAGAGCCCT TCTTTGCTCT CGCCAAGGAA 
CTCTATCCTG GGCAGTTCAA GCCGACCATC TGCCACTACT TCATCCGCCT GCTGAAGGAA 
AAAGGACTGC TCCTGCGCTG CTACACACAG AACATAGACA CCCTGGAGCG AGTGGCTGGG 
CTGGAGCCCG AAGACCTGGT GGAGGCCCAC GGCACCTTCT ACACGTCCCA CTGCATCAGC 
TCAGGCTGCC GGCAGGAGTA CTCACTAAGC TGGATGAAAG AGAAGATCTT CTCCGAGGTG 
ACTCCCAAGT GTGAGAAATG TCAGAGCGTG GTGAAGCCTG ATATCGTGTT CTTCGGCGAG 
AACCTCCCAG CGCGTTTCTT CTCCTGCATG CAGTCAGACT TCCTAAAGGT GGACCTCCTT 
ATCATCATGG GCACCTCCCT GCAGGTGCAG CCCTTCGCGT CCCTCATCGG CAAGGCGCCC 
CTGTCGACCC CGCGCCTGCT CATCAACAAG GAGAAGACTG GCCAGACTGA CCCTTTCCTC 
GGGATGATGA TGGCCCTCGG AGGAGGCATG GACTTTGACT CCAAGAAGGC CTACAGGGAC 
GTGGCCTGGC TGGGCGACTG TGACCAGGGC TGCCTGGCCC TCGCCGACCT CCTTGGATGG 
AAGAAGGAGC TGGAGGACCT TGTTCGGAAG GAGCATGCCA GCATAGATGC CCAGTCGGGG 
TCGGGGGCCT CCAACCCCGC TACTTCAGCT TCCCCCAGGA ATTCTCCACC ACCTCCCACC 
AAGGAGGAGC CCAGGACCAC TGAGGGAGAG AAACCCCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024833778.1
CDS	225..1286
Translation	MDFLRNFFSQTLGLGTQKERLLDELTLEGVSRYMQSERCRRVICLVGAGISTSAGIPDFRSPNTGLYANLEKYRLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFIRLLKEKGLLLRCYTQNIDTLERVAGLEPEDLVEAHGTFYTSHCISSGCRQEYSLSWMKEKIFSEVTPKCEKCQSVVKPDIVFFGENLPARFFSCMQSDFLKVDLLIIMGTSLQVQPFASLIGKAPLSTPRLLINKEKTGQTDPFLGMMMALGGGMDFDSKKAYRDVAWLGDCDQGCLALADLLGWKKELEDLVRKEHASIDAQSGSGASNPATSASPRNSPPPPTKEEPRTTEGEKPQ

Target ORF information:

RefSeq Version	XM_024978010.1
Organism	Bos taurus(cattle)
Definition	Bos taurus sirtuin 2 (SIRT2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024978010.1

ORF Insert Sequence:

ATGGACTTCC TGCGGAATTT CTTCTCCCAG ACTCTGGGCC TGGGCACCCA GAAGGAGCGA 
CTCCTGGACG AACTAACCCT GGAAGGAGTG AGCCGCTACA TGCAGAGCGA GCGCTGTCGC 
AGGGTCATCT GTTTGGTGGG AGCTGGAATC TCCACTTCCG CGGGTATCCC TGACTTTCGG 
TCCCCAAACA CGGGCCTCTA TGCCAACCTG GAGAAATACC GTCTTCCCTA CCCGGAGGCC 
ATCTTTGAAA TCAGCTACTT CAAGAAACAT CCAGAGCCCT TCTTTGCTCT CGCCAAGGAA 
CTCTATCCTG GGCAGTTCAA GCCGACCATC TGCCACTACT TCATCCGCCT GCTGAAGGAA 
AAAGGACTGC TCCTGCGCTG CTACACACAG AACATAGACA CCCTGGAGCG AGTGGCTGGG 
CTGGAGCCCG AAGACCTGGT GGAGGCCCAC GGCACCTTCT ACACGTCCCA CTGCATCAGC 
TCAGGCTGCC GGCAGGAGTA CTCACTAAGC TGGATGAAAG AGAAGATCTT CTCCGAGGTG 
ACTCCCAAGT GTGAGAAATG TCAGAGCGTG GTGAAGCCTG ATATCGTGTT CTTCGGCGAG 
AACCTCCCAG CGCGTTTCTT CTCCTGCATG CAGTCAGACT TCCTAAAGGT GGACCTCCTT 
ATCATCATGG GCACCTCCCT GCAGGTGCAG CCCTTCGCGT CCCTCATCGG CAAGGCGCCC 
CTGTCGACCC CGCGCCTGCT CATCAACAAG GAGAAGACTG GCCAGACTGA CCCTTTCCTC 
GGGATGATGA TGGCCCTCGG AGGAGGCATG GACTTTGACT CCAAGAAGGC CTACAGGGAC 
GTGGCCTGGC TGGGCGACTG TGACCAGGGC TGCCTGGCCC TCGCCGACCT CCTTGGATGG 
AAGAAGGAGC TGGAGGACCT TGTTCGGAAG GAGCATGCCA GCATAGATGC CCAGTCGGGG 
TCGGGGGCCT CCAACCCCGC TACTTCAGCT TCCCCCAGGA ATTCTCCACC ACCTCCCACC 
AAGGAGGAGC CCAGGACCAC TGAGGGAGAG AAACCCCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Haplotype distribution in the class I sirtuin genes and their associations with ultrasound carcass traits in Qinchuan cattle (Bos taurus).
Molecular and cellular probes29(3)167-71(2015 Jun)
Gui L,Hao R,Zhang Y,Zhao X,Zan L

Expression of the SIRT2 gene and its relationship with body size traits in Qinchuan cattle (Bos taurus).
International journal of molecular sciences16(2)2458-71(2015 Jan)
Gui LS,Zhang YR,Liu GY,Zan LS

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SIRT2 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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