Slc12a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc12a2
Entrez Gene ID	83629
Full Name	solute carrier family 12 member 2
Synonyms	Bsc2,Nkcc1
General protein information	Preferred Names solute carrier family 12 member 2 Names solute carrier family 12 member 2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 solute carrier family 12 (sodium/potassium/chloride transporters), member 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 18 Map Location: 18q12.1
Summary	Na/K/2Cl cotransporter involved in maintainence of intracellular Cl(-) levels [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006254752.3	XP_006254814.1	solute carrier family 12 member 2 isoform X1
NM_031798.1	NP_113986.1	solute carrier family 12 member 2

Pathways from BioSystems

Homologies

	SLC12A2	XP_001098624.1
Rattus norvegicus (Norway rat)	Slc12a2	NP_113986.1
Danio rerio (zebrafish)	slc12a2	NP_001002080.1
Drosophila melanogaster (fruit fly)	Ncc69	NP_648572.1
Homo sapiens (human)	SLC12A2	NP_001243390.1
Bos taurus (cattle)	SLC12A2	NP_777207.1
Gallus gallus (chicken)	SLC12A2	XP_004949435.1
Pan troglodytes (chimpanzee)	SLC12A2	XP_003310846.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001557	XP_321556.3
Xenopus tropicalis (tropical clawed frog)	slc12a2	XP_004910531.1
Canis lupus familiaris (dog)	SLC12A2	XP_538611.5
Mus musculus (house mouse)	Slc12a2	NP_033220.2

Gene Ontology
Bibliography

Related articles in PubMed

WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats.
Bhuiyan MIH, Song S, Yuan H, Begum G, Kofler J, Kahle KT, Yang SS, Lin SH, Alper SL, Subramanya AR, Sun D
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism37(8)2780-2794(2017 Aug)

Long-term alcohol exposure elicits hippocampal nonsynaptic epileptiform activity changes associated with expression and functional changes in NKCC1, KCC2 co-transporters and Na
Santos LEC, Rodrigues AM, Lopes MR, Costa VDC, Scorza CA, Scorza FA, Cavalheiro EA, Almeida AG
Neuroscience340530-541(2017 Jan)

WNK1 kinase balances T cell adhesion versus migration in vivo.
K?chl R, Thelen F, Vanes L, Braz?o TF, Fountain K, Xie J, Huang CL, Lyck R, Stein JV, Tybulewicz VL
Nature immunology17(9)1075-83(2016 09)

Regulation of the cell surface expression of chloride transporters during epileptogenesis.
Gonz?lez MI
Neuroscience letters628213-8(2016 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Early IGF-1 primes visual cortex maturation and accelerates developmental switch between NKCC1 and KCC2 chloride transporters in enriched animals. Early enrichment and IGF-1 administration produced a decrease in the ratio between NKCC1 and KCC2 cation/chloride transporters, suggesting that enrichment, via IGF-1, may hasten the developmental switch of neuronal GABAergic responses from excitation to inhibition.
Title: Early IGF-1 primes visual cortex maturation and accelerates developmental switch between NKCC1 and KCC2 chloride transporters in enriched animals.

Cata suggest that chronic stress impairs GABAergic inhibition, resulting in hypothalamic-pituitary-adrenal axis hyperactivity through upregulation of the cation chloride cotransporter Na+-K+-Cl--Cl- .
Title: Chronic Unpredictable Mild Stress Induces Loss of GABA Inhibition in Corticotrophin-Releasing Hormone-Expressing Neurons through NKCC1 Upregulation.

Study assessed the nonsynaptic epileptiform activities (NEA) induced in the dentate gyrus after 4weeks of ethanol consumption; increment of the cotransporter expression was determined, and the effects of NKCC1 increasing the ictogenesis of the group treated with a low dosage of ethanol and the neurodegenerative process after ictal-like activity on the group treated with a high dosage were demonstrated.
Title: Long-term alcohol exposure elicits hippocampal nonsynaptic epileptiform activity changes associated with expression and functional changes in NKCC1, KCC2 co-transporters and Na

Findings suggest that aberrant regulation of the plasma membrane levels of NKCC1 might contribute to the impartment of GABAergic neurotransmission and that NKCC1 dysfunction might be relevant for the initial appearance of spontaneous seizures.
Title: Regulation of the cell surface expression of chloride transporters during epileptogenesis.

Results indicate that NKCC1 activity transiently decreases in dorsal root ganglion neurons at fetal stages near term
Title: NKCC1 downregulation induces hyperpolarizing shift of GABA responsiveness at near term fetal stages in rat cultured dorsal root ganglion neurons.

The following Slc12a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc12a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13551	NM_031798.1 Latest version!	Rattus norvegicus solute carrier family 12 member 2 (Slc12a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00
ORa38405	XM_006254752.3 Latest version!	Rattus norvegicus solute carrier family 12 member 2 (Slc12a2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc12a2 ( NM_031798.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113986.1 Rattus norvegicus solute carrier family 12 member 2 (Slc12a2), mRNA.

Price & Availability↑

CloneID	ORa13551
Clone ID Related Accession (Same CDS sequence)	NM_031798.1
Accession Version	NM_031798.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3612bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-06
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier family 12 member 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF051561.1. On Jan 7, 2005 this sequence version replaced XM_346513.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF051561.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCCCG GGCCCGCGGC GCCCTCGTCT GGCGCCCCGC GGCCCGCCCG GGATGGGGAC 
GCGCCGCTGA CTGCCGCCGG GGTGGACCTG CCCGGCACGG CCGTACTCTC CGGTCGAGAG 
GATGCTACCG CTGGGAGCCA GGCCGGCGGC GGGGTGCGCG GAGAGGGAAC CCCGGCCGCT 
GGCGATGGGC TGGGCAAACC TCTGGGGCCC ACCCCCAGCC AGAGCCGCTT CCAGGTGGAC 
CCGGTTTCCG AGAACGCCGG GCGGGCCGCG GCTGCTGCAG CTGCAGCGGC GGCTGCGGCG 
GCTGCCGGGG CAGCGGGCAA GGAGACCCCC GCGGCTGGGA AAGCCGGCAC TGAGAGCGGC 
GTGGCCAAGG GCAGCGAGGA AGCCAAGGGC CGCTTCCGCG TGAACTTCGT GGACCCGGCT 
GCCTCCTCGT CGGCGGACGA CAGCCTGTCG GATGCGGCGG GAGTCGGTGG CGACGGGCCC 
AACGTGAGCT CCCAGAACGG CGGGGACACG GTGCTGAGCG AGGGCAGCAG CCTGCACTCG 
GGTGGTGGCA GTGGACACCA CCAGCAGTAC TACTATGACA CCCACACCAA CACTTACTAC 
CTGCGCACCT TCGGCCACAA CACCATGGAC GCGGTGCCCA GGATCGACCA CTACCGGCAC 
ACGGCCGCGC AGCTGGGCGA GAAGCTGCTC CGGCCCAGCC TGGGAGAGTT CCACGATGAG 
CTGGAAAAGG AACCTTTTGA GGATGGTTTT GCGAATGGAG AAGAAAGTAC TCCAACCAGA 
GATGCTGTGG TCACATACAC TGCCGAAAGT AAAGGAGTTG TAAAGTTTGG CTGGATCAAG 
GGTGTTTTAG TACGATGTAT GTTGAATATT TGGGGTGTGA TGCTCTTTAT TCGATTGTCA 
TGGATTGTGG GTCAGGCTGG AATAGGTCTC TCCGTTCTTG TAATAGCAAT GGCCACTGTT 
GTGACAACCA TCACAGGATT GTCTACTTCA GCAATAGCTA CCAATGGATT CGTGAGAGGA 
GGAGGAGCAT ACTATTTAAT CTCTAGAAGT CTAGGGCCAG AATTTGGCGG TGCGATTGGC 
TTGATCTTCG CTTTTCCCAA TGCAGTGGCA GTTGCTATGT ATGTTGTTGG ATTCGCAGAG 
ACTGTAGTGG AGCTGCTTAA GGAACATTCC ATACTTATGA TAGATGAAAT CAATGACATC 
CGAATTATTG GAGCCATTAC AGTGGTGGTT CTTCTGGGCA TCTCAGTGGC CGGAATGGAG 
TGGGAAGCAA AGGCTCAGAT CGTCCTTCTG GTGATTCTTC TTCTGGCCAT CGCTGACTTC 
GTCATAGGAA CATTTATCTC ACTGGACAGC AAGAAGCCCA AGGGTTTCTT TGGCTATAAA 
TCTGAAATAT TTAGTGAGAA CTTTGGACCG GATTTTCGAG AAGAAGAGAC TTTCTTTTCT 
GTATTCGCCA TCTTTTTTCC TGCTGCAACT GGTATTCTAG CTGGGGCGAA CATCTCGGGT 
GACCTTGCAG ATCCTCAGTC AGCCATACCC AAAGGAACGC TCTTAGCCAT TTTGATTACG 
ACAGTGGTTT ACATAGGAAT CGCAGTGTCT GTAGGTTCTT GTGTTGTCCG GGATGCCACT 
GGGAACGTTA ATGACACCAT TACAACAGAG CTAACTAACT GTACTTCTGC AGCCTGCAAA 
TTAAACTTTG ACTTTTCCTA CTGTGAAAGC AACACCTGTT CTTATGGGCT AATGAACAAC 
TTTCAGGTGA TGAGCATGGT GTCAGGATTT GCACCCCTGA TCTCTGCGGG TATCTTTTCA 
GCCACACTCT CATCAGCACT GGCATCTCTT GTGAGTGCTC CCAAAATATT TCAGGCTCTA 
TGTAAGGACA ATATCTACCC AGCTTTCCAG ATGTTTGCGA AAGGTTATGG AAAAAATAAT 
GAACCTCTTC GTGGTTACAT CTTAACATTC TTAATTGCAC TTGGATTCAT CTTAATTGCT 
GAATTGAATG TCATTGCTCC AATTATCTCT AATTTCTTTC TCGCATCATA CGCCTTAATC 
AACTTTTCTG TATTCCATGC GTCACTTGCA AAGTCTCCAG GGTGGCGTCC TGCGTTCAAG 
TACTACAACA TGTGGATCTC CCTTACTGGA GCGATTCTCT GCTGCATAGT GATGTTCGTC 
ATTAACTGGT GGGCTGCACT GCTCACATAT GTGATAGTTC TTGGACTGTA CATTTATGTC 
ACTTACAAAA AGCCAGATGT GAACTGGGGA TCCTCCACAC AAGCGCTGAC TTACCTCAGC 
GCACTGCAGC ATTCAATCCG TCTTTCCGGG GTGGAGGACC ATGTGAAAAA CTTCAGGCCA 
CAGTGTCTTG TAATGACAGG TTCTCCAAAC TCACGGCCTG CTTTACTGCA TCTTGTTCAT 
GACTTCACGA AAAATGTTGG TTTAATGATC TGTGGCCATG TGCATATGGG TCCCCGAAGA 
CAAGCTATGA AAGAGATGTC CATTGATCAA GCCAAATATC AGCGATGGCT CATTAAAAAC 
AAAATGAAGG CTTTCTACGC TCCGGTTCAC GCAGATGACT TGCGGGAAGG TGCACAGTAC 
CTGATGCAGG CTGCTGGACT TGGTCGTATG AAACCAAACA CACTTGTCCT CGGATTTAAG 
AAAGATTGGT TACAAGCAGA TATGAGGGAT GTGGATATGT ATATAAACTT ATTTCATGAT 
GCTTTTGACA TACAGTATGG AGTTGTGGTC ATTCGCCTAA AGGAAGGACT GGATATATCA 
CACCTCCAAG GACAAGAAGA ATTATTGTCA TCACAAGAAA AGTCACCTGG TACCAAGGAT 
GTGGTAGTAA ATGTGGACTA CAGTAAGAAG TCAGATCAAG ATGCTTTCAA AGCATCTGGT 
GAAAAACCTA TTACACAGAA AGATGAGGAA GAGGATGGCA AGACTTCAAC TCAGCCACTG 
TTGAAAAAAG AATCCAAGGG CCCCGTGGCA CCTTTAAATG TAGCTGACCA AAAGCTTCTT 
GAAGCTAGCA CACAGTTTCA GAAAAAACAA GGGAAGAATA CTATAGATGT CTGGTGGCTT 
TTTGATGATG GAGGTTTGAC CTTGTTGATA CCCTATCTTC TGACAACCAA GAAAAAGTGG 
AAAGATTGTA AGATCCGAGT ATTCATTGGT GGAAAGATAA ACAGAATAGA CCATGACCGG 
AGAGCGATGG CTACTTTACT CAGTAAATTC CGAATAGACT TCTCCGATAT CATGGTCCTA 
GGAGACATCA ACACCAAACC AAAAAAGGAA AACATCGTCG CTTTTGATGA CATGATTGAG 
CCATACAGAC TTCACGAGGA TGATAAAGAG CAGGATATTG CAGACAAAAT GAAAGAGGAT 
GAGCCCTGGC GCATCACAGA CAACGAGCTG GAGCTCTACA AGACCAAGAC ATATCGGCAG 
ATCAGGTTAA ATGAATTATT AAAGGAGCAT TCAAGCACAG CTAATATTAT TGTCATGAGT 
CTTCCAGTTG CCCGGAAGGG TGCTGTGTCC AGCGCGCTGT ACATGGCTTG GTTAGAAGCT 
CTGTCTAAGG ACCTGCCACC AATCCTGCTG GTTCGTGGGA ATCATCAGAG CGTCCTTACC 
TTCTACTCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113986.1
CDS	128..3739
Translation	MEPGPAAPSSGAPRPARDGDAPLTAAGVDLPGTAVLSGREDATAGSQAGGGVRGEGTPAAGDGLGKPLGPTPSQSRFQVDPVSENAGRAAAAAAAAAAAAAAGAAGKETPAAGKAGTESGVAKGSEEAKGRFRVNFVDPAASSSADDSLSDAAGVGGDGPNVSSQNGGDTVLSEGSSLHSGGGSGHHQQYYYDTHTNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKLLRPSLGEFHDELEKEPFEDGFANGEESTPTRDAVVTYTAESKGVVKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIAMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFPNAVAVAMYVVGFAETVVELLKEHSILMIDEINDIRIIGAITVVVLLGISVAGMEWEAKAQIVLLVILLLAIADFVIGTFISLDSKKPKGFFGYKSEIFSENFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTVVYIGIAVSVGSCVVRDATGNVNDTITTELTNCTSAACKLNFDFSYCESNTCSYGLMNNFQVMSMVSGFAPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLTGAILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQALTYLSALQHSIRLSGVEDHVKNFRPQCLVMTGSPNSRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEGLDISHLQGQEELLSSQEKSPGTKDVVVNVDYSKKSDQDAFKASGEKPITQKDEEEDGKTSTQPLLKKESKGPVAPLNVADQKLLEASTQFQKKQGKNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGGKINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKENIVAFDDMIEPYRLHEDDKEQDIADKMKEDEPWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLPPILLVRGNHQSVLTFYS

Target ORF information:

RefSeq Version	NM_031798.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 12 member 2 (Slc12a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031798.1

ORF Insert Sequence:

ATGGAGCCCG GGCCCGCGGC GCCCTCGTCT GGCGCCCCGC GGCCCGCCCG GGATGGGGAC 
GCGCCGCTGA CTGCCGCCGG GGTGGACCTG CCCGGCACGG CCGTACTCTC CGGTCGAGAG 
GATGCTACCG CTGGGAGCCA GGCCGGCGGC GGGGTGCGCG GAGAGGGAAC CCCGGCCGCT 
GGCGATGGGC TGGGCAAACC TCTGGGGCCC ACCCCCAGCC AGAGCCGCTT CCAGGTGGAC 
CCGGTTTCCG AGAACGCCGG GCGGGCCGCG GCTGCTGCAG CTGCAGCGGC GGCTGCGGCG 
GCTGCCGGGG CAGCGGGCAA GGAGACCCCC GCGGCTGGGA AAGCCGGCAC TGAGAGCGGC 
GTGGCCAAGG GCAGCGAGGA AGCCAAGGGC CGCTTCCGCG TGAACTTCGT GGACCCGGCT 
GCCTCCTCGT CGGCGGACGA CAGCCTGTCG GATGCGGCGG GAGTCGGTGG CGACGGGCCC 
AACGTGAGCT CCCAGAACGG CGGGGACACG GTGCTGAGCG AGGGCAGCAG CCTGCACTCG 
GGTGGTGGCA GTGGACACCA CCAGCAGTAC TACTATGACA CCCACACCAA CACTTACTAC 
CTGCGCACCT TCGGCCACAA CACCATGGAC GCGGTGCCCA GGATCGACCA CTACCGGCAC 
ACGGCCGCGC AGCTGGGCGA GAAGCTGCTC CGGCCCAGCC TGGGAGAGTT CCACGATGAG 
CTGGAAAAGG AACCTTTTGA GGATGGTTTT GCGAATGGAG AAGAAAGTAC TCCAACCAGA 
GATGCTGTGG TCACATACAC TGCCGAAAGT AAAGGAGTTG TAAAGTTTGG CTGGATCAAG 
GGTGTTTTAG TACGATGTAT GTTGAATATT TGGGGTGTGA TGCTCTTTAT TCGATTGTCA 
TGGATTGTGG GTCAGGCTGG AATAGGTCTC TCCGTTCTTG TAATAGCAAT GGCCACTGTT 
GTGACAACCA TCACAGGATT GTCTACTTCA GCAATAGCTA CCAATGGATT CGTGAGAGGA 
GGAGGAGCAT ACTATTTAAT CTCTAGAAGT CTAGGGCCAG AATTTGGCGG TGCGATTGGC 
TTGATCTTCG CTTTTCCCAA TGCAGTGGCA GTTGCTATGT ATGTTGTTGG ATTCGCAGAG 
ACTGTAGTGG AGCTGCTTAA GGAACATTCC ATACTTATGA TAGATGAAAT CAATGACATC 
CGAATTATTG GAGCCATTAC AGTGGTGGTT CTTCTGGGCA TCTCAGTGGC CGGAATGGAG 
TGGGAAGCAA AGGCTCAGAT CGTCCTTCTG GTGATTCTTC TTCTGGCCAT CGCTGACTTC 
GTCATAGGAA CATTTATCTC ACTGGACAGC AAGAAGCCCA AGGGTTTCTT TGGCTATAAA 
TCTGAAATAT TTAGTGAGAA CTTTGGACCG GATTTTCGAG AAGAAGAGAC TTTCTTTTCT 
GTATTCGCCA TCTTTTTTCC TGCTGCAACT GGTATTCTAG CTGGGGCGAA CATCTCGGGT 
GACCTTGCAG ATCCTCAGTC AGCCATACCC AAAGGAACGC TCTTAGCCAT TTTGATTACG 
ACAGTGGTTT ACATAGGAAT CGCAGTGTCT GTAGGTTCTT GTGTTGTCCG GGATGCCACT 
GGGAACGTTA ATGACACCAT TACAACAGAG CTAACTAACT GTACTTCTGC AGCCTGCAAA 
TTAAACTTTG ACTTTTCCTA CTGTGAAAGC AACACCTGTT CTTATGGGCT AATGAACAAC 
TTTCAGGTGA TGAGCATGGT GTCAGGATTT GCACCCCTGA TCTCTGCGGG TATCTTTTCA 
GCCACACTCT CATCAGCACT GGCATCTCTT GTGAGTGCTC CCAAAATATT TCAGGCTCTA 
TGTAAGGACA ATATCTACCC AGCTTTCCAG ATGTTTGCGA AAGGTTATGG AAAAAATAAT 
GAACCTCTTC GTGGTTACAT CTTAACATTC TTAATTGCAC TTGGATTCAT CTTAATTGCT 
GAATTGAATG TCATTGCTCC AATTATCTCT AATTTCTTTC TCGCATCATA CGCCTTAATC 
AACTTTTCTG TATTCCATGC GTCACTTGCA AAGTCTCCAG GGTGGCGTCC TGCGTTCAAG 
TACTACAACA TGTGGATCTC CCTTACTGGA GCGATTCTCT GCTGCATAGT GATGTTCGTC 
ATTAACTGGT GGGCTGCACT GCTCACATAT GTGATAGTTC TTGGACTGTA CATTTATGTC 
ACTTACAAAA AGCCAGATGT GAACTGGGGA TCCTCCACAC AAGCGCTGAC TTACCTCAGC 
GCACTGCAGC ATTCAATCCG TCTTTCCGGG GTGGAGGACC ATGTGAAAAA CTTCAGGCCA 
CAGTGTCTTG TAATGACAGG TTCTCCAAAC TCACGGCCTG CTTTACTGCA TCTTGTTCAT 
GACTTCACGA AAAATGTTGG TTTAATGATC TGTGGCCATG TGCATATGGG TCCCCGAAGA 
CAAGCTATGA AAGAGATGTC CATTGATCAA GCCAAATATC AGCGATGGCT CATTAAAAAC 
AAAATGAAGG CTTTCTACGC TCCGGTTCAC GCAGATGACT TGCGGGAAGG TGCACAGTAC 
CTGATGCAGG CTGCTGGACT TGGTCGTATG AAACCAAACA CACTTGTCCT CGGATTTAAG 
AAAGATTGGT TACAAGCAGA TATGAGGGAT GTGGATATGT ATATAAACTT ATTTCATGAT 
GCTTTTGACA TACAGTATGG AGTTGTGGTC ATTCGCCTAA AGGAAGGACT GGATATATCA 
CACCTCCAAG GACAAGAAGA ATTATTGTCA TCACAAGAAA AGTCACCTGG TACCAAGGAT 
GTGGTAGTAA ATGTGGACTA CAGTAAGAAG TCAGATCAAG ATGCTTTCAA AGCATCTGGT 
GAAAAACCTA TTACACAGAA AGATGAGGAA GAGGATGGCA AGACTTCAAC TCAGCCACTG 
TTGAAAAAAG AATCCAAGGG CCCCGTGGCA CCTTTAAATG TAGCTGACCA AAAGCTTCTT 
GAAGCTAGCA CACAGTTTCA GAAAAAACAA GGGAAGAATA CTATAGATGT CTGGTGGCTT 
TTTGATGATG GAGGTTTGAC CTTGTTGATA CCCTATCTTC TGACAACCAA GAAAAAGTGG 
AAAGATTGTA AGATCCGAGT ATTCATTGGT GGAAAGATAA ACAGAATAGA CCATGACCGG 
AGAGCGATGG CTACTTTACT CAGTAAATTC CGAATAGACT TCTCCGATAT CATGGTCCTA 
GGAGACATCA ACACCAAACC AAAAAAGGAA AACATCGTCG CTTTTGATGA CATGATTGAG 
CCATACAGAC TTCACGAGGA TGATAAAGAG CAGGATATTG CAGACAAAAT GAAAGAGGAT 
GAGCCCTGGC GCATCACAGA CAACGAGCTG GAGCTCTACA AGACCAAGAC ATATCGGCAG 
ATCAGGTTAA ATGAATTATT AAAGGAGCAT TCAAGCACAG CTAATATTAT TGTCATGAGT 
CTTCCAGTTG CCCGGAAGGG TGCTGTGTCC AGCGCGCTGT ACATGGCTTG GTTAGAAGCT 
CTGTCTAAGG ACCTGCCACC AATCCTGCTG GTTCGTGGGA ATCATCAGAG CGTCCTTACC 
TTCTACTCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc12a2 ( XM_006254752.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006254814.1 Rattus norvegicus solute carrier family 12 member 2 (Slc12a2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa38405
Clone ID Related Accession (Same CDS sequence)	XM_006254752.3
Accession Version	XM_006254752.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3564bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier family 12 member 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254752.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCCG GGCCCGCGGC GCCCTCGTCT GGCGCCCCGC GGCCCGCCCG GGATGGGGAC 
GCGCCGCTGA CTGCCGCCGG GGTGGACCTG CCCGGCACGG CCGTACTCTC CGGTCGAGAG 
GATGCTACCG CTGGGAGCCA GGCCGGCGGC GGGGTGCGCG GAGAGGGAAC CCCGGCCGCT 
GGCGATGGGC TGGGCAAACC TCTGGGGCCC ACCCCCAGCC AGAGCCGCTT CCAGGTGGAC 
CCGGTTTCCG AGAACGCCGG GCGGGCCGCG GCTGCTGCAG CTGCAGCGGC GGCTGCGGCG 
GCTGCCGGGG CAGCGGGCAA GGAGACCCCC GCGGCTGGGA AAGCCGGCAC TGAGAGCGGC 
GTGGCCAAGG GCAGCGAGGA AGCCAAGGGC CGCTTCCGCG TGAACTTCGT GGACCCGGCT 
GCCTCCTCGT CGGCGGACGA CAGCCTGTCG GATGCGGCGG GGGTCGGTGG CGACGGGCCC 
AACGTGAGCT TCCAGAACGG CGGGGACACG GTGCTGAGCG AGGGCAGCAG CCTGCACTCG 
GGTGGTGGCA GTGGACACCA CCAGCAGTAC TACTATGACA CCCACACCAA CACCTACTAC 
CTGCGCACCT TCGGCCACAA CACCATGGAC GCGGTGCCCA GGATCGACCA CTACCGGCAC 
ACGGCCGCGC AGCTGGGCGA GAAGCTGCTC CGGCCCAGCC TGGCAGAGCT CCACGATGAG 
CTGGAAAAGG AACCTTTTGA GGATGGCTTT GCGAATGGAG AAGAAAGTAC TCCAACCAGA 
GATGCTGTGG TCACATACAC TGCCGAAAGT AAAGGAGTTG TAAAGTTTGG CTGGATCAAG 
GGTGTATTAG TACGATGTAT GTTGAACATT TGGGGTGTGA TGCTCTTTAT TCGATTGTCA 
TGGATTGTGG GTCAGGCTGG AATAGGTCTC TCCGTTCTTG TAATAGCAAT GGCCACTGTT 
GTGACAACCA TCACAGGATT GTCTACTTCA GCAATAGCTA CCAATGGATT CGTGAGAGGA 
GGAGGAGCAT ACTATTTAAT CTCTAGAAGT CTAGGGCCAG AATTTGGCGG TGCGATTGGC 
TTGATCTTCG CTTTTGCCAA TGCAGTGGCA GTTGCTATGT ATGTTGTTGG ATTCGCAGAG 
ACTGTAGTGG AGCTGCTTAA GGAACATTCC ATACTTATGA TAGATGAAAT CAATGACATC 
CGAATTATTG GAGCCATTAC AGTGGTGGTT CTTCTGGGCA TCTCAGTGGC CGGAATGGAG 
TGGGAAGCAA AGGCTCAGAT CGTCCTTCTG GTGATTCTTC TTCTGGCCAT CGCTGACTTC 
GTCATAGGAA CATTTATCTC ACTGGACAGC AAGAAGCCCA AGGGTTTCTT TGGCTATAAA 
TCTGAAATAT TTAGTGAGAA CTTTGGACCG GATTTTCGAG AAGAAGAGAC TTTCTTTTCT 
GTATTCGCCA TCTTTTTTCC TGCTGCAACT GGTATTCTAG CTGGGGCGAA CATCTCGGGT 
GACCTTGCAG ATCCTCAGTC AGCCATACCC AAAGGAACGC TCTTAGCCAT TTTGATTACG 
ACAGTGGTTT ACATAGGAAT CGCAGTGTCT GTAGGTTCTT GTGTTGTCCG GGATGCCACT 
GGGAACGTTA ATGACACCAT TACAACAGAG CTAACTAACT GTACTTCTGC AGCCTGCAAA 
TTAAACTTTG ACTTTTCCTA CTGTGAAAGC AACACCTGTT CTTATGGGCT AATGAACAAC 
TTTCAGGTGA TGAGCATGGT GTCAGGATTT GCACCCCTGA TCTCTGCGGG TATCTTTTCA 
GCCACACTCT CATCAGCACT GGCATCTCTT GTGAGTGCTC CCAAAATATT TCAGGCTCTA 
TGTAAGGACA ATATCTACCC AGCTTTCCAG ATGTTTGCGA AAGGTTATGG AAAAAATAAT 
GAACCTCTTC GTGGTTACAT CTTAACATTC TTAATTGCAC TTGGATTCAT CTTAATTGCT 
GAATTGAATG TCATTGCTCC AATTATCTCT AATTTCTTTC TCGCATCATA CGCCTTAATC 
AACTTTTCTG TATTCCATGC GTCACTTGCA AAGTCTCCAG GGTGGCGTCC TGCGTTCAAG 
TACTACAACA TGTGGATCTC CCTTACTGGA GCGATTCTCT GCTGCATAGT GATGTTCGTC 
ATTAACTGGT GGGCTGCACT GCTCACGTAT GTGATAGTTC TTGGACTGTA CATTTATGTC 
ACTTACAAAA AGCCAGATGT GAACTGGGGA TCCTCCACAC AAGCGCTGAC TTACCTCAGC 
GCACTGCAGC ATTCAATCCG TCTTTCCGGG GTGGAGGACC ATGTGAAAAA CTTCAGGCCA 
CAGTGTCTTG TAATGACAGG TTCTCCAAAC TCACGGCCTG CTTTACTGCA TCTTGTTCAT 
GACTTCACGA AAAATGTTGG TTTAATGATC TGTGGCCATG TGCATATGGG TCCCCGAAGA 
CAAGCTATGA AAGAGATGTC CATTGATCAA GCCAAATATC AGCGATGGCT CATTAAAAAC 
AAAATGAAGG CTTTCTACGC TCCGGTTCAC GCAGATGACT TGCGGGAAGG TGCACAGTAC 
CTGATGCAGG CTGCTGGACT TGGTCGTATG AAACCAAACA CACTTGTCCT CGGATTTAAG 
AAAGATTGGT TACAAGCAGA TATGAGGGAT GTGGATATGT ATATAAACTT ATTTCATGAT 
GCTTTTGACA TACAGTATGG AGTTGTGGTC ATTCGCCTAA AGGAAGGACT GGATATATCA 
CACCTCCAAG GACAAGAAGA ATTATTGTCA TCACAAGAAA AGTCACCTGG TACCAAGGAT 
GTGGTAGTAA ATGTGGACTA CAGTAAGAAG TCAGATCAAG ATGCTTTCAA AGCATCTGGT 
GAAAAACCTA TTACACAGAA AGAATCCAAG GGCCCCGTGG CACCTTTAAA TGTAGCTGAC 
CAAAAGCTTC TTGAAGCTAG CACACAGTTT CAGAAAAAAC AAGGGAAGAA TACTATAGAT 
GTCTGGTGGC TTTTTGATGA TGGAGGTTTG ACCTTGTTGA TACCCTATCT TCTGACAACC 
AAGAAAAAGT GGAAAGATTG TAAGATCCGA GTATTCATTG GTGGAAAGAT AAACAGAATA 
GACCATGACC GGAGAGCGAT GGCTACTTTA CTCAGTAAAT TCCGAATAGA CTTCTCCGAT 
ATCATGGTCC TAGGAGACAT CAACACCAAA CCAAAAAAGG AAAACATCGT CGCTTTTGAT 
GACATGATTG AGCCATACAG ACTTCACGAG GATGATAAAG AGCAGGATAT TGCAGACAAA 
ATGAAAGAGG ATGAGCCCTG GCGCATCACA GACAACGAGC TGGAGCTCTA CAAGACCAAG 
ACATATCGGC AGATCAGGTT AAATGAATTA TTAAAGGAGC ATTCAAGCAC AGCTAATATT 
ATTGTCATGA GTCTTCCAGT TGCCCGGAAG GGTGCTGTGT CCAGCGCGCT GTACATGGCT 
TGGTTAGAAG CTCTGTCTAA GGACCTGCCA CCAATCCTGC TGGTTCGTGG GAATCATCAG 
AGCGTCCTTA CCTTCTACTC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006254814.1
CDS	97..3660
Translation	MEPGPAAPSSGAPRPARDGDAPLTAAGVDLPGTAVLSGREDATAGSQAGGGVRGEGTPAAGDGLGKPLGPTPSQSRFQVDPVSENAGRAAAAAAAAAAAAAAGAAGKETPAAGKAGTESGVAKGSEEAKGRFRVNFVDPAASSSADDSLSDAAGVGGDGPNVSFQNGGDTVLSEGSSLHSGGGSGHHQQYYYDTHTNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEKEPFEDGFANGEESTPTRDAVVTYTAESKGVVKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIAMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMIDEINDIRIIGAITVVVLLGISVAGMEWEAKAQIVLLVILLLAIADFVIGTFISLDSKKPKGFFGYKSEIFSENFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTVVYIGIAVSVGSCVVRDATGNVNDTITTELTNCTSAACKLNFDFSYCESNTCSYGLMNNFQVMSMVSGFAPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLTGAILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQALTYLSALQHSIRLSGVEDHVKNFRPQCLVMTGSPNSRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEGLDISHLQGQEELLSSQEKSPGTKDVVVNVDYSKKSDQDAFKASGEKPITQKESKGPVAPLNVADQKLLEASTQFQKKQGKNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGGKINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKENIVAFDDMIEPYRLHEDDKEQDIADKMKEDEPWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLPPILLVRGNHQSVLTFYS

Target ORF information:

RefSeq Version	XM_006254752.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 12 member 2 (Slc12a2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006254752.3

ORF Insert Sequence:

ATGGAGCCCG GGCCCGCGGC GCCCTCGTCT GGCGCCCCGC GGCCCGCCCG GGATGGGGAC 
GCGCCGCTGA CTGCCGCCGG GGTGGACCTG CCCGGCACGG CCGTACTCTC CGGTCGAGAG 
GATGCTACCG CTGGGAGCCA GGCCGGCGGC GGGGTGCGCG GAGAGGGAAC CCCGGCCGCT 
GGCGATGGGC TGGGCAAACC TCTGGGGCCC ACCCCCAGCC AGAGCCGCTT CCAGGTGGAC 
CCGGTTTCCG AGAACGCCGG GCGGGCCGCG GCTGCTGCAG CTGCAGCGGC GGCTGCGGCG 
GCTGCCGGGG CAGCGGGCAA GGAGACCCCC GCGGCTGGGA AAGCCGGCAC TGAGAGCGGC 
GTGGCCAAGG GCAGCGAGGA AGCCAAGGGC CGCTTCCGCG TGAACTTCGT GGACCCGGCT 
GCCTCCTCGT CGGCGGACGA CAGCCTGTCG GATGCGGCGG GGGTCGGTGG CGACGGGCCC 
AACGTGAGCT TCCAGAACGG CGGGGACACG GTGCTGAGCG AGGGCAGCAG CCTGCACTCG 
GGTGGTGGCA GTGGACACCA CCAGCAGTAC TACTATGACA CCCACACCAA CACCTACTAC 
CTGCGCACCT TCGGCCACAA CACCATGGAC GCGGTGCCCA GGATCGACCA CTACCGGCAC 
ACGGCCGCGC AGCTGGGCGA GAAGCTGCTC CGGCCCAGCC TGGCAGAGCT CCACGATGAG 
CTGGAAAAGG AACCTTTTGA GGATGGCTTT GCGAATGGAG AAGAAAGTAC TCCAACCAGA 
GATGCTGTGG TCACATACAC TGCCGAAAGT AAAGGAGTTG TAAAGTTTGG CTGGATCAAG 
GGTGTATTAG TACGATGTAT GTTGAACATT TGGGGTGTGA TGCTCTTTAT TCGATTGTCA 
TGGATTGTGG GTCAGGCTGG AATAGGTCTC TCCGTTCTTG TAATAGCAAT GGCCACTGTT 
GTGACAACCA TCACAGGATT GTCTACTTCA GCAATAGCTA CCAATGGATT CGTGAGAGGA 
GGAGGAGCAT ACTATTTAAT CTCTAGAAGT CTAGGGCCAG AATTTGGCGG TGCGATTGGC 
TTGATCTTCG CTTTTGCCAA TGCAGTGGCA GTTGCTATGT ATGTTGTTGG ATTCGCAGAG 
ACTGTAGTGG AGCTGCTTAA GGAACATTCC ATACTTATGA TAGATGAAAT CAATGACATC 
CGAATTATTG GAGCCATTAC AGTGGTGGTT CTTCTGGGCA TCTCAGTGGC CGGAATGGAG 
TGGGAAGCAA AGGCTCAGAT CGTCCTTCTG GTGATTCTTC TTCTGGCCAT CGCTGACTTC 
GTCATAGGAA CATTTATCTC ACTGGACAGC AAGAAGCCCA AGGGTTTCTT TGGCTATAAA 
TCTGAAATAT TTAGTGAGAA CTTTGGACCG GATTTTCGAG AAGAAGAGAC TTTCTTTTCT 
GTATTCGCCA TCTTTTTTCC TGCTGCAACT GGTATTCTAG CTGGGGCGAA CATCTCGGGT 
GACCTTGCAG ATCCTCAGTC AGCCATACCC AAAGGAACGC TCTTAGCCAT TTTGATTACG 
ACAGTGGTTT ACATAGGAAT CGCAGTGTCT GTAGGTTCTT GTGTTGTCCG GGATGCCACT 
GGGAACGTTA ATGACACCAT TACAACAGAG CTAACTAACT GTACTTCTGC AGCCTGCAAA 
TTAAACTTTG ACTTTTCCTA CTGTGAAAGC AACACCTGTT CTTATGGGCT AATGAACAAC 
TTTCAGGTGA TGAGCATGGT GTCAGGATTT GCACCCCTGA TCTCTGCGGG TATCTTTTCA 
GCCACACTCT CATCAGCACT GGCATCTCTT GTGAGTGCTC CCAAAATATT TCAGGCTCTA 
TGTAAGGACA ATATCTACCC AGCTTTCCAG ATGTTTGCGA AAGGTTATGG AAAAAATAAT 
GAACCTCTTC GTGGTTACAT CTTAACATTC TTAATTGCAC TTGGATTCAT CTTAATTGCT 
GAATTGAATG TCATTGCTCC AATTATCTCT AATTTCTTTC TCGCATCATA CGCCTTAATC 
AACTTTTCTG TATTCCATGC GTCACTTGCA AAGTCTCCAG GGTGGCGTCC TGCGTTCAAG 
TACTACAACA TGTGGATCTC CCTTACTGGA GCGATTCTCT GCTGCATAGT GATGTTCGTC 
ATTAACTGGT GGGCTGCACT GCTCACGTAT GTGATAGTTC TTGGACTGTA CATTTATGTC 
ACTTACAAAA AGCCAGATGT GAACTGGGGA TCCTCCACAC AAGCGCTGAC TTACCTCAGC 
GCACTGCAGC ATTCAATCCG TCTTTCCGGG GTGGAGGACC ATGTGAAAAA CTTCAGGCCA 
CAGTGTCTTG TAATGACAGG TTCTCCAAAC TCACGGCCTG CTTTACTGCA TCTTGTTCAT 
GACTTCACGA AAAATGTTGG TTTAATGATC TGTGGCCATG TGCATATGGG TCCCCGAAGA 
CAAGCTATGA AAGAGATGTC CATTGATCAA GCCAAATATC AGCGATGGCT CATTAAAAAC 
AAAATGAAGG CTTTCTACGC TCCGGTTCAC GCAGATGACT TGCGGGAAGG TGCACAGTAC 
CTGATGCAGG CTGCTGGACT TGGTCGTATG AAACCAAACA CACTTGTCCT CGGATTTAAG 
AAAGATTGGT TACAAGCAGA TATGAGGGAT GTGGATATGT ATATAAACTT ATTTCATGAT 
GCTTTTGACA TACAGTATGG AGTTGTGGTC ATTCGCCTAA AGGAAGGACT GGATATATCA 
CACCTCCAAG GACAAGAAGA ATTATTGTCA TCACAAGAAA AGTCACCTGG TACCAAGGAT 
GTGGTAGTAA ATGTGGACTA CAGTAAGAAG TCAGATCAAG ATGCTTTCAA AGCATCTGGT 
GAAAAACCTA TTACACAGAA AGAATCCAAG GGCCCCGTGG CACCTTTAAA TGTAGCTGAC 
CAAAAGCTTC TTGAAGCTAG CACACAGTTT CAGAAAAAAC AAGGGAAGAA TACTATAGAT 
GTCTGGTGGC TTTTTGATGA TGGAGGTTTG ACCTTGTTGA TACCCTATCT TCTGACAACC 
AAGAAAAAGT GGAAAGATTG TAAGATCCGA GTATTCATTG GTGGAAAGAT AAACAGAATA 
GACCATGACC GGAGAGCGAT GGCTACTTTA CTCAGTAAAT TCCGAATAGA CTTCTCCGAT 
ATCATGGTCC TAGGAGACAT CAACACCAAA CCAAAAAAGG AAAACATCGT CGCTTTTGAT 
GACATGATTG AGCCATACAG ACTTCACGAG GATGATAAAG AGCAGGATAT TGCAGACAAA 
ATGAAAGAGG ATGAGCCCTG GCGCATCACA GACAACGAGC TGGAGCTCTA CAAGACCAAG 
ACATATCGGC AGATCAGGTT AAATGAATTA TTAAAGGAGC ATTCAAGCAC AGCTAATATT 
ATTGTCATGA GTCTTCCAGT TGCCCGGAAG GGTGCTGTGT CCAGCGCGCT GTACATGGCT 
TGGTTAGAAG CTCTGTCTAA GGACCTGCCA CCAATCCTGC TGGTTCGTGG GAATCATCAG 
AGCGTCCTTA CCTTCTACTC TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism37(8)2780-2794(2017 Aug)
Bhuiyan MIH,Song S,Yuan H,Begum G,Kofler J,Kahle KT,Yang SS,Lin SH,Alper SL,Subramanya AR,Sun D

Long-term alcohol exposure elicits hippocampal nonsynaptic epileptiform activity changes associated with expression and functional changes in NKCC1, KCC2 co-transporters and Na
Neuroscience340530-541(2017 Jan)
Santos LEC,Rodrigues AM,Lopes MR,Costa VDC,Scorza CA,Scorza FA,Cavalheiro EA,Almeida AG

WNK1 kinase balances T cell adhesion versus migration in vivo.
Nature immunology17(9)1075-83(2016 09)
K?chl R,Thelen F,Vanes L,Braz?o TF,Fountain K,Xie J,Huang CL,Lyck R,Stein JV,Tybulewicz VL

Regulation of the cell surface expression of chloride transporters during epileptogenesis.
Neuroscience letters628213-8(2016 Aug)
Gonz?lez MI

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Slc12a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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