The following Pde3a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pde3a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa43395 | |
| Clone ID Related Accession (Same CDS sequence) | XM_008763422.2 | |
| Accession Version | XM_008763422.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2469bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008763422.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGGCCATT CAGAATGGGA CCACAAGAGA GGGTCACGAG GATCCCAGTC AGGAACCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_008761644.1 |
| CDS | 1042..3510 |
| Translation |
Target ORF information:
Target ORF information:
|
 XM_008763422.2 |
1 | ATGGGCCATT CAGAATGGGA CCACAAGAGA GGGTCACGAG GATCCCAGTC AGGAACCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa03684 | |
| Clone ID Related Accession (Same CDS sequence) | NM_017337.1 | |
| Accession Version | NM_017337.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3426bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-20 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U38179.1. On Jun 25, 2006 this sequence version replaced XM_001073892.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U38179.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCAGTGC GGGGCGAGGC CGCCCAAGAC TGGGCCAAGC CCGGTCTCCG AGGGCCGAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_059033.1 |
| CDS | 1..3426 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_017337.1 |
1 | ATGGCAGTGC GGGGCGAGGC CGCCCAAGAC TGGGCCAAGC CCGGTCTCCG AGGGCCGAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
cUMP hydrolysis by PDE3A. |
Phosphoinositide 3-kinase ? protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterases. |
Phosphodiesterase 3A expression is modulated by nitric oxide in rat pulmonary artery smooth muscle cells. |
Cyclic GMP signaling is involved in the luteinizing hormone-dependent meiotic maturation of mouse oocytes. |
Iloprost- and isoproterenol-induced increases in cAMP are regulated by different phosphodiesterases in erythrocytes of both rabbits and humans. |
