Zeb1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Zeb1
Entrez Gene ID	25705
Full Name	zinc finger E-box binding homeobox 1
Synonyms	Tcf8,Zfhx1a,deltaEF1
General protein information	Preferred Names zinc finger E-box binding homeobox 1 Names zinc finger E-box-binding homeobox 1 TCF-8 transcription factor 8 (represses interleukin 2 expression) zfhep zinc finger homeodomain enhancer-binding protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17q12.1
Summary	zinc finger and homeodomain protein that binds T3-response elements [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001308265.1	NP_001295194.1	zinc finger E-box-binding homeobox 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ZEB1	NP_001167567.1
Bos taurus (cattle)	ZEB1	NP_001193519.1
Mus musculus (house mouse)	Zeb1	NP_035676.1
Gallus gallus (chicken)	ZEB1	NP_990462.1
Canis lupus familiaris (dog)	ZEB1	XP_003638927.1
	ZEB1	XP_001089463.2
Xenopus tropicalis (tropical clawed frog)	zeb1	NP_001015808.1
Pan troglodytes (chimpanzee)	ZEB1	XP_003312560.1
Rattus norvegicus (Norway rat)	Zeb1	NP_037296.1
Danio rerio (zebrafish)	zeb1b	NP_571784.1

Gene Ontology
Bibliography

Related articles in PubMed

XIST accelerates neuropathic pain progression through regulation of miR-150 and ZEB1 in CCI rat models.
Yan XT, Lu JM, Wang Y, Cheng XL, He XH, Zheng WZ, Chen H, Wang YL
Journal of cellular physiology(2018 Jan)

Inhibition of miR-200b/miR-429 contributes to neuropathic pain development through targeting zinc finger E box binding protein-1.
Yan XT, Zhao Y, Cheng XL, He XH, Wang Y, Zheng WZ, Chen H, Wang YL
Journal of cellular physiology(2017 Nov)

Transforming growth factor ?1 antagonizes the transcription, expression and vascular signaling of guanylyl cyclase/natriuretic peptide receptor A - role of ?EF1.
Sen A, Kumar P, Garg R, Lindsey SH, Katakam PV, Bloodworth M, Pandey KN
The FEBS journal283(9)1767-81(2016 05)

MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis.
Filios SR, Xu G, Chen J, Hong K, Jing G, Shalev A
The Journal of biological chemistry289(52)36275-83(2014 Dec)

Functional impact of ZEB1 mutations associated with posterior polymorphous and Fuchs' endothelial corneal dystrophies.
Chung DW, Frausto RF, Ann LB, Jang MS, Aldave AJ
Investigative ophthalmology & visual science55(10)6159-66(2014 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results suggest that an antagonistic cascade exists between the TGF-beta1/Smad/deltaEF1 pathways and Npr1 expression and receptor signaling that is relevant to renal and vascular remodeling, and may be critical in the regulation of blood pressure and cardiovascular homeostasis.
Title: Transforming growth factor ?1 antagonizes the transcription, expression and vascular signaling of guanylyl cyclase/natriuretic peptide receptor A - role of ?EF1.

TXNIP and diabetes up-regulate miR-200 expression in primary islets and miR-200 directly targets Zeb1 promoting beta cell apoptosis.
Title: MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis.

It was demonstrated that the miR-200 family was responsible for protecting tubular epithelial cells from mesenchymal transition by target suppression of zinc finger E-box-binding homeobox (ZEB) 1 and ZEB2, which are E-cadherin transcriptional repressors.
Title: The miR-200 family regulates TGF-?1-induced renal tubular epithelial to mesenchymal transition through Smad pathway by targeting ZEB1 and ZEB2 expression.

Zeb1 is required for several TrkB-induced effects in vitro and in vivo, including metastasis.
Title: Zeb1 is required for TrkB-induced epithelial-mesenchymal transition, anoikis resistance and metastasis.

ZEB1 is the most likely candidate gene contributing to multiple sclerosis pathogenesis and inflammation.
Title: Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat.

The following Zeb1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Zeb1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa43206	NM_001308265.1 Latest version!	Rattus norvegicus zinc finger E-box binding homeobox 1 (Zeb1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Zeb1 ( NM_001308265.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001295194.1 Rattus norvegicus zinc finger E-box binding homeobox 1 (Zeb1), mRNA.

Price & Availability↑

CloneID	ORa43206
Clone ID Related Accession (Same CDS sequence)	NM_001308265.1
Accession Version	NM_001308265.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3330bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-30
Organism	Rattus norvegicus(Norway rat)
Product	zinc finger E-box-binding homeobox 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FQ078592.1, U51583.1 and AABR07028042.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U51583.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689600 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGATG GCCCCAGGTG TAAGCGCAGA AAGCAGGCGA ACCCGCGGCG CAATAACGTT 
ACAAATTATA ATACTGTGGT AGAAGCAAAT TCAGATTCGG ATGATGAAGA CAAACTCCAT 
ATTGTGGAAG AAGAAAGTGT CACAGATGCA GCTGACTGTG AAGGTGGTGT GCCAGATGAT 
GAGCTGCCAA CAGACCAGAC AGTGTTACCA GGAGGCAGTG ACAGGGCGGG CAGTGCCAAG 
AACTGCTGGC AAGACGACGT AAAAGATGAC GAATGCGACT CAGATGCAGA AAACGAGCAA 
AACCATGATC CCAACGTGGA AGAGTTCCTG CAGCAACAGG ACACCGCGGT CATCTACCCT 
GAGGCACCCG AGGAGGACCA GCGGCAGGGC ACGCCAGAAG CCAGCGGTCA TGATGACAAT 
GGAACACCAG ATGCATTTTC CCAGTTGCTC ACCTGCCCGT ATTGTGATAG AGGCTACAAG 
CGCTTTACCT CTTTGAAAGA ACACATTAAG TACCGCCATG AGAAGAATGA AGACAACTTC 
AGCTGCTCCC TGTGCAGTTA CACCTTTGCA TACAGAACCC AGCTTGAACG TCATATGACA 
TCACATAAGT CAGGAAGAGA GCAAAGACAT GTGACACAGT CTGGAGGTAA CCGTAAGTTC 
AAGTGCACCG AGTGTGGGAA AGCGTTCAAG TACAAACACC ATCTGAAGGA GCACTTACGG 
ATCCACAGTG GAGAGAAGCC ATATGAATGC CCAAACTGCA AGAAACGTTT TTCCCATTCT 
GGCTCTTATA GCTCACACAT AAGCAGTAAG AAGTGTATTA GCTTGATGCC TGTGAATGGT 
AGGCCCAGAT CAGGACTCAA GACATCTCAG TGTTCCTCGC CATCTCTTTC AACATCACCA 
GGCAGTCCCA CACGCCCACA GATACGGCAG AAGATAGAGA ATAAACCCCT TCAAGAACCG 
CTTTCTGTAA ACCAAATCAA AACTGAACCT GTGGATTATG AGTTCAAACC CATAGTGGTT 
GCTTCAGGAA TCAACTGTTC AACCCCTTTA CAAAATGGGG TTTTTAGCGG TGGTGGCCAA 
TTGCAGGCAA CCAGTTCTCC TCAGGGTGTG GTGCAAGCTG TTGTTCTGCC AACAGTTGGT 
TTGGTATCTC CCATAAGTAT CAACTTAAGT GACATTCAGA ATGTACTTAA AGTGGCTGTA 
GATGGTAACA TAATACGACA GGTTTTGGAG AATAATCAAG CCAGTCTTGC ATCCAAAGAG 
CAAGAAGCCG TGAGTGCTTC ATCCATCCAG CAGGGCGGCC ATTCTGTCAT TTCTGCCATC 
AGTCTTCCTT TAGTTGATCA GGATGGCACA ACCAAAATCA TCATCAACTA CAGTCTTGAG 
CAGCCCGGCC AACTTCAGGT TGTTCCCCAG AATCTAAAGA AAGAAAACCC AGCCCCTCCA 
AAGAGCTGCA AAAGTGAGAA GTCACCAGAA GATCTTACTG TCAAGTCAGA GAAGGACAAA 
AGCTTTGATG GGGCTGCGGA TGAGAGCACT TGCCTTTTGT GTGAGGACTG CCCAGGAGAC 
CTCAATGCAC TTCCAGAACT AAAGCACTAT GACCCAGAGC ACCCTGCTCA ACCTCCACCC 
CCTGCCCCAG CCACCGAGAA GCCAGAGTCC TCTGCTTCAT CAGCCGGCAA TGGAGATTTG 
TCTCCCAGTC AGCCACCTTT AAAGAACCTT CTGTCGCTCT TAAAAGCCTA CTATGCTCTG 
AATGCACAGC CAAGCACAGA AGAGCTCACC AAGATTGCCG ATTCTGTGAA CCTGCCGCTG 
GATGTAGTTA AAAAGTGGTT TGAAAAGATG CAAGCTGGAC AGATTCCCGG GCAGTCTCTT 
GAACCACCTT CTCCAGGACC GGGGTCAGGA AACATCCCTG CAAAAACTGA GGAGCAGCCT 
CAACCTGTGG ATGGAAATGA GCCCCAGGAA GACAGCACAC GTGGACAGAG TCCTCTCAAG 
ATGACAAGCT CTCCAGTTTT ACCAGTAGGA TCAGCCATTA ACGGTTCCAG AAGTTGCACA 
TCATCCCCAT CCCCTCTAAA CCTTTCCTCA GCCAGGAACC CGCAGGGTTA CTCTTGTGTG 
TCAGAGGGTA CCCAGGAGGA GCCCCAAGTA GAACCTCTTG ATCTCTCACT ACCAAAGCAA 
CAGGGAGAGT TACTGGAAAG GTCGACAGTC AGTAGCGTTT ACCAGAACAG TGTTTATTCT 
GTCCAGGAAG AACCCTTGAA CTTGTCTTGT GCAAAAAAGG AGCCACAAAA GGACAGTTGT 
GTTACAGACT CAGAACCAGT TGTAAATGTA GTCCCACCAA GTGCCAACCC CATAAACATT 
GCTATTCCTA CAGTCACTGC CCAGTTACCC ACAATCGTGG CCATCGCTGA CCAGAACAGT 
GTTCCGTGCT TACGGGCACT CGCTGCCAAC AAGCAGACTA TTCTGATTCC CCAAGTGGCA 
TATACATACT CCGCTACAGT CAGCCCAGCC ATGCAGGAGC CACCAGTGAA GGTGATCCAG 
CCAAATGGAA ACCAGGATGA AAGACAAGAC ACTAGCTCAG AAGGAGTCTC CGTGGAGGAC 
CAGAATGACT CTGACTGCAC GCCACCCAAA AAGAAAACTC GGAAGGCAGA GAATGGGATG 
TACGCATGTG ACCTGTGTGA CAAGATATTT CAGAAGAGCA GCTCCCTGCT GAGACACAAA 
TATGAGCATA CAGGTAAGAG GCCCCACGAG TGCGGAATCT GTAGAAAGGC ATTTAAACAC 
AAGCATCATT TGATTGAGCA CATGCGACTG CACTCTGGGG AAAAGCCCTA CCAATGTGAC 
AAGTGTGGCA AGCGCTTCTC ACACTCGGGG TCTTACTCTC AACACATGAA TCACCGCTAC 
TCCTACTGCA AGAGAGGAGC TGAAGACAGA GATGCCATGG AGCAGGAAGA CACTGGGCCG 
GAAGCCCTGC CGGAAGTCCT GCCCACTGAG CTTGTTGGTG CCCGGGCATC TCCCTCACAG 
GCTGACTCGG ACGAGAGAGA AAGTTTGACA AGGGAAGAGG ATGAAGACAG TGAAAAGGAG 
GAGGAGGAGG AGGATAAAGA GATGGAAGAA TTGCAGGAAG ACAAGGAATG TGAGAACCCA 
CAGGAGGAGG AGGAGGAGGA AGAGGAGGAA GAAGAAGAAG AGGAGGAGGA AGAGGAAGAG 
GAGGCAGAGG AAGCTGAGCA TGAGGCGGCA GCAGCCAAGA CTGGGGGTGC AGTGGAGGAG 
GAAGCGGCTC AGCAGGCAGG CAGCTTCCAG CAGAAGGCCA GCGGGAGCGA GAGCAAGCGA 
CTGTCTGAAG AGAAGACAAA TGAAGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001295194.1
CDS	24..3353
Translation	MADGPRCKRRKQANPRRNNVTNYNTVVEANSDSDDEDKLHIVEEESVTDAADCEGGVPDDELPTDQTVLPGGSDRAGSAKNCWQDDVKDDECDSDAENEQNHDPNVEEFLQQQDTAVIYPEAPEEDQRQGTPEASGHDDNGTPDAFSQLLTCPYCDRGYKRFTSLKEHIKYRHEKNEDNFSCSLCSYTFAYRTQLERHMTSHKSGREQRHVTQSGGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCISLMPVNGRPRSGLKTSQCSSPSLSTSPGSPTRPQIRQKIENKPLQEPLSVNQIKTEPVDYEFKPIVVASGINCSTPLQNGVFSGGGQLQATSSPQGVVQAVVLPTVGLVSPISINLSDIQNVLKVAVDGNIIRQVLENNQASLASKEQEAVSASSIQQGGHSVISAISLPLVDQDGTTKIIINYSLEQPGQLQVVPQNLKKENPAPPKSCKSEKSPEDLTVKSEKDKSFDGAADESTCLLCEDCPGDLNALPELKHYDPEHPAQPPPPAPATEKPESSASSAGNGDLSPSQPPLKNLLSLLKAYYALNAQPSTEELTKIADSVNLPLDVVKKWFEKMQAGQIPGQSLEPPSPGPGSGNIPAKTEEQPQPVDGNEPQEDSTRGQSPLKMTSSPVLPVGSAINGSRSCTSSPSPLNLSSARNPQGYSCVSEGTQEEPQVEPLDLSLPKQQGELLERSTVSSVYQNSVYSVQEEPLNLSCAKKEPQKDSCVTDSEPVVNVVPPSANPINIAIPTVTAQLPTIVAIADQNSVPCLRALAANKQTILIPQVAYTYSATVSPAMQEPPVKVIQPNGNQDERQDTSSEGVSVEDQNDSDCTPPKKKTRKAENGMYACDLCDKIFQKSSSLLRHKYEHTGKRPHECGICRKAFKHKHHLIEHMRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKRGAEDRDAMEQEDTGPEALPEVLPTELVGARASPSQADSDERESLTREEDEDSEKEEEEEDKEMEELQEDKECENPQEEEEEEEEEEEEEEEEEEEEAEEAEHEAAAAKTGGAVEEEAAQQAGSFQQKASGSESKRLSEEKTNEA

Target ORF information:

RefSeq Version	NM_001308265.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus zinc finger E-box binding homeobox 1 (Zeb1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001308265.1

ORF Insert Sequence:

ATGGCGGATG GCCCCAGGTG TAAGCGCAGA AAGCAGGCGA ACCCGCGGCG CAATAACGTT 
ACAAATTATA ATACTGTGGT AGAAGCAAAT TCAGATTCGG ATGATGAAGA CAAACTCCAT 
ATTGTGGAAG AAGAAAGTGT CACAGATGCA GCTGACTGTG AAGGTGGTGT GCCAGATGAT 
GAGCTGCCAA CAGACCAGAC AGTGTTACCA GGAGGCAGTG ACAGGGCGGG CAGTGCCAAG 
AACTGCTGGC AAGACGACGT AAAAGATGAC GAATGCGACT CAGATGCAGA AAACGAGCAA 
AACCATGATC CCAACGTGGA AGAGTTCCTG CAGCAACAGG ACACCGCGGT CATCTACCCT 
GAGGCACCCG AGGAGGACCA GCGGCAGGGC ACGCCAGAAG CCAGCGGTCA TGATGACAAT 
GGAACACCAG ATGCATTTTC CCAGTTGCTC ACCTGCCCGT ATTGTGATAG AGGCTACAAG 
CGCTTTACCT CTTTGAAAGA ACACATTAAG TACCGCCATG AGAAGAATGA AGACAACTTC 
AGCTGCTCCC TGTGCAGTTA CACCTTTGCA TACAGAACCC AGCTTGAACG TCATATGACA 
TCACATAAGT CAGGAAGAGA GCAAAGACAT GTGACACAGT CTGGAGGTAA CCGTAAGTTC 
AAGTGCACCG AGTGTGGGAA AGCGTTCAAG TACAAACACC ATCTGAAGGA GCACTTACGG 
ATCCACAGTG GAGAGAAGCC ATATGAATGC CCAAACTGCA AGAAACGTTT TTCCCATTCT 
GGCTCTTATA GCTCACACAT AAGCAGTAAG AAGTGTATTA GCTTGATGCC TGTGAATGGT 
AGGCCCAGAT CAGGACTCAA GACATCTCAG TGTTCCTCGC CATCTCTTTC AACATCACCA 
GGCAGTCCCA CACGCCCACA GATACGGCAG AAGATAGAGA ATAAACCCCT TCAAGAACCG 
CTTTCTGTAA ACCAAATCAA AACTGAACCT GTGGATTATG AGTTCAAACC CATAGTGGTT 
GCTTCAGGAA TCAACTGTTC AACCCCTTTA CAAAATGGGG TTTTTAGCGG TGGTGGCCAA 
TTGCAGGCAA CCAGTTCTCC TCAGGGTGTG GTGCAAGCTG TTGTTCTGCC AACAGTTGGT 
TTGGTATCTC CCATAAGTAT CAACTTAAGT GACATTCAGA ATGTACTTAA AGTGGCTGTA 
GATGGTAACA TAATACGACA GGTTTTGGAG AATAATCAAG CCAGTCTTGC ATCCAAAGAG 
CAAGAAGCCG TGAGTGCTTC ATCCATCCAG CAGGGCGGCC ATTCTGTCAT TTCTGCCATC 
AGTCTTCCTT TAGTTGATCA GGATGGCACA ACCAAAATCA TCATCAACTA CAGTCTTGAG 
CAGCCCGGCC AACTTCAGGT TGTTCCCCAG AATCTAAAGA AAGAAAACCC AGCCCCTCCA 
AAGAGCTGCA AAAGTGAGAA GTCACCAGAA GATCTTACTG TCAAGTCAGA GAAGGACAAA 
AGCTTTGATG GGGCTGCGGA TGAGAGCACT TGCCTTTTGT GTGAGGACTG CCCAGGAGAC 
CTCAATGCAC TTCCAGAACT AAAGCACTAT GACCCAGAGC ACCCTGCTCA ACCTCCACCC 
CCTGCCCCAG CCACCGAGAA GCCAGAGTCC TCTGCTTCAT CAGCCGGCAA TGGAGATTTG 
TCTCCCAGTC AGCCACCTTT AAAGAACCTT CTGTCGCTCT TAAAAGCCTA CTATGCTCTG 
AATGCACAGC CAAGCACAGA AGAGCTCACC AAGATTGCCG ATTCTGTGAA CCTGCCGCTG 
GATGTAGTTA AAAAGTGGTT TGAAAAGATG CAAGCTGGAC AGATTCCCGG GCAGTCTCTT 
GAACCACCTT CTCCAGGACC GGGGTCAGGA AACATCCCTG CAAAAACTGA GGAGCAGCCT 
CAACCTGTGG ATGGAAATGA GCCCCAGGAA GACAGCACAC GTGGACAGAG TCCTCTCAAG 
ATGACAAGCT CTCCAGTTTT ACCAGTAGGA TCAGCCATTA ACGGTTCCAG AAGTTGCACA 
TCATCCCCAT CCCCTCTAAA CCTTTCCTCA GCCAGGAACC CGCAGGGTTA CTCTTGTGTG 
TCAGAGGGTA CCCAGGAGGA GCCCCAAGTA GAACCTCTTG ATCTCTCACT ACCAAAGCAA 
CAGGGAGAGT TACTGGAAAG GTCGACAGTC AGTAGCGTTT ACCAGAACAG TGTTTATTCT 
GTCCAGGAAG AACCCTTGAA CTTGTCTTGT GCAAAAAAGG AGCCACAAAA GGACAGTTGT 
GTTACAGACT CAGAACCAGT TGTAAATGTA GTCCCACCAA GTGCCAACCC CATAAACATT 
GCTATTCCTA CAGTCACTGC CCAGTTACCC ACAATCGTGG CCATCGCTGA CCAGAACAGT 
GTTCCGTGCT TACGGGCACT CGCTGCCAAC AAGCAGACTA TTCTGATTCC CCAAGTGGCA 
TATACATACT CCGCTACAGT CAGCCCAGCC ATGCAGGAGC CACCAGTGAA GGTGATCCAG 
CCAAATGGAA ACCAGGATGA AAGACAAGAC ACTAGCTCAG AAGGAGTCTC CGTGGAGGAC 
CAGAATGACT CTGACTGCAC GCCACCCAAA AAGAAAACTC GGAAGGCAGA GAATGGGATG 
TACGCATGTG ACCTGTGTGA CAAGATATTT CAGAAGAGCA GCTCCCTGCT GAGACACAAA 
TATGAGCATA CAGGTAAGAG GCCCCACGAG TGCGGAATCT GTAGAAAGGC ATTTAAACAC 
AAGCATCATT TGATTGAGCA CATGCGACTG CACTCTGGGG AAAAGCCCTA CCAATGTGAC 
AAGTGTGGCA AGCGCTTCTC ACACTCGGGG TCTTACTCTC AACACATGAA TCACCGCTAC 
TCCTACTGCA AGAGAGGAGC TGAAGACAGA GATGCCATGG AGCAGGAAGA CACTGGGCCG 
GAAGCCCTGC CGGAAGTCCT GCCCACTGAG CTTGTTGGTG CCCGGGCATC TCCCTCACAG 
GCTGACTCGG ACGAGAGAGA AAGTTTGACA AGGGAAGAGG ATGAAGACAG TGAAAAGGAG 
GAGGAGGAGG AGGATAAAGA GATGGAAGAA TTGCAGGAAG ACAAGGAATG TGAGAACCCA 
CAGGAGGAGG AGGAGGAGGA AGAGGAGGAA GAAGAAGAAG AGGAGGAGGA AGAGGAAGAG 
GAGGCAGAGG AAGCTGAGCA TGAGGCGGCA GCAGCCAAGA CTGGGGGTGC AGTGGAGGAG 
GAAGCGGCTC AGCAGGCAGG CAGCTTCCAG CAGAAGGCCA GCGGGAGCGA GAGCAAGCGA 
CTGTCTGAAG AGAAGACAAA TGAAGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

XIST accelerates neuropathic pain progression through regulation of miR-150 and ZEB1 in CCI rat models.
Journal of cellular physiology(2018 Jan)
Yan XT,Lu JM,Wang Y,Cheng XL,He XH,Zheng WZ,Chen H,Wang YL

Inhibition of miR-200b/miR-429 contributes to neuropathic pain development through targeting zinc finger E box binding protein-1.
Journal of cellular physiology(2017 Nov)
Yan XT,Zhao Y,Cheng XL,He XH,Wang Y,Zheng WZ,Chen H,Wang YL

Transforming growth factor ?1 antagonizes the transcription, expression and vascular signaling of guanylyl cyclase/natriuretic peptide receptor A - role of ?EF1.
The FEBS journal283(9)1767-81(2016 05)
Sen A,Kumar P,Garg R,Lindsey SH,Katakam PV,Bloodworth M,Pandey KN

MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis.
The Journal of biological chemistry289(52)36275-83(2014 Dec)
Filios SR,Xu G,Chen J,Hong K,Jing G,Shalev A

Functional impact of ZEB1 mutations associated with posterior polymorphous and Fuchs' endothelial corneal dystrophies.
Investigative ophthalmology & visual science55(10)6159-66(2014 Sep)
Chung DW,Frausto RF,Ann LB,Jang MS,Aldave AJ

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Zeb1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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