Gene Symbol | ZEB1 |
Entrez Gene ID | 6935 |
Full Name | zinc finger E-box binding homeobox 1 |
Synonyms | AREB6,BZP,DELTAEF1,FECD6,NIL2A,PPCD3,TCF8,ZFHEP,ZFHX1A |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010]. |
Disorder MIM: | |
Disorder Html: | Corneal dystrophy, posterior polymorphous, 3, 609141 (3); Corneal dystrophy, Fuchs endothelial, 6, 613270 (3) |