Chek2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Chek2
Entrez Gene ID	114212
Full Name	checkpoint kinase 2
Synonyms	Chk2,Rad53
General protein information	Preferred Names checkpoint kinase 2 Names serine/threonine-protein kinase Chk2 CHK2 checkpoint homolog protein kinase Chk2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q16
Summary	kinase involved in ATM-dependent DNA damage checkpoint pathway [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006249518.3	XP_006249580.1	serine/threonine-protein kinase Chk2 isoform X1
XM_008769308.2	XP_008767530.1	serine/threonine-protein kinase Chk2 isoform X2
XM_006249519.2	XP_006249581.1	serine/threonine-protein kinase Chk2 isoform X1
XM_006249520.3	XP_006249582.1	serine/threonine-protein kinase Chk2 isoform X1
XM_006249521.3	XP_006249583.1	serine/threonine-protein kinase Chk2 isoform X1
NM_053677.1	NP_446129.1	serine/threonine-protein kinase Chk2

Pathways from BioSystems

Homologies

Homo sapiens (human)	CHEK2	NP_001005735.1
Rattus norvegicus (Norway rat)	Chek2	NP_446129.1
Saccharomyces cerevisiae (baker's yeast)	RAD53	NP_015172.1
Bos taurus (cattle)	CHEK2	NP_001029703.1
Gallus gallus (chicken)	CHEK2	NP_001073576.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009784	XP_318879.3
Caenorhabditis elegans (roundworm)	CELE_T08D2.7	NP_508060.1
Caenorhabditis elegans (roundworm)	chk-2	NP_001024271.1
Kluyveromyces lactis	KLLA0F11143g	XP_455587.1
	CHEK2	XP_001101658.1
Mus musculus (house mouse)	Chek2	NP_057890.1
Danio rerio (zebrafish)	chek2	NP_956339.1
Pan troglodytes (chimpanzee)	CHEK2	XP_003317205.1
Canis lupus familiaris (dog)	CHEK2	XP_005636447.1
Drosophila melanogaster (fruit fly)	lok	NP_724241.1
Eremothecium gossypii	AGOS_ACR142W	NP_983544.2
Xenopus tropicalis (tropical clawed frog)	chek2	NP_001119996.1

Gene Ontology
Bibliography

Related articles in PubMed

Bisphenol A induces oxidative stress-associated DNA damage in INS-1 cells.
Xin F, Jiang L, Liu X, Geng C, Wang W, Zhong L, Yang G, Chen M
Mutation research. Genetic toxicology and environmental mutagenesis76929-33(2014 Jul)

Premature cardiac senescence in DahlS.Z-Lepr(fa)/Lepr(fa) rats as a new animal model of metabolic syndrome.
Takahashi K, Takatsu M, Hattori T, Murase T, Ohura S, Takeshita Y, Watanabe S, Murohara T, Nagata K
Nagoya journal of medical science76(1-2)35-49(2014 Feb)

PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair.
Khoury-Haddad H, Guttmann-Raviv N, Ipenberg I, Huggins D, Jeyasekharan AD, Ayoub N
Proceedings of the National Academy of Sciences of the United States of America111(7)E728-37(2014 Feb)

Nek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblasts.
Nguyen CL, Possemato R, Bauerlein EL, Xie A, Scully R, Hahn WC
Molecular and cellular biology32(19)3963-77(2012 Oct)

Cellular distribution of cell cycle-related molecules in the renal tubules of rats treated with renal carcinogens for 28 days: relationship between cell cycle aberration and carcinogenesis.
Taniai E, Hayashi H, Yafune A, Watanabe M, Akane H, Suzuki K, Mitsumori K, Shibutani M
Archives of toxicology86(9)1453-64(2012 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Chk-2 is an important novel component of anoikis-promoting machinery of intestinal epithelial cells
Title: Tumor suppressor protein kinase Chk2 is a mediator of anoikis of intestinal epithelial cells.

Data demonstrate that polyamines regulate c-Myc translation in IECs through HuR phosphorylation by Chk2 and provide new insight into the molecular functions of cellular polyamines.
Title: Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation.

an important role for the DNA damage response mediated by ATR-Chk2 in p53 activation and renal cell apoptosis during cisplatin nephrotoxicity.
Title: ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis.

The following Chek2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Chek2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa10283	NM_053677.1 Latest version!	Rattus norvegicus checkpoint kinase 2 (Chek2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa10283	XM_006249520.3 Latest version!	Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa10283	XM_006249518.3 Latest version!	Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa10283	XM_006249521.3 Latest version!	Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa10283	XM_006249519.2 Latest version!	Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa43925	XM_008769308.2 Latest version!	Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Chek2 ( NM_053677.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446129.1 Rattus norvegicus checkpoint kinase 2 (Chek2), mRNA.

Price & Availability↑

CloneID	ORa10283
Clone ID Related Accession (Same CDS sequence)	XM_006249518.3 , XM_006249519.2 , XM_006249520.3 , XM_006249521.3 , NM_053677.1
Accession Version	NM_053677.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-26
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase Chk2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF134054.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF134054.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAAGAGTC ATCAGTCCCA CGGCAGCACC TCCTCGAAGG CTCATGACAG TGCTTCCTGT 
TCACAGTCTC AAGGCGGCTT CAGCCAGTCC CAAGGCACCC CCTCTCAGTT GCACGACCTC 
TCACAGTATC AGGGTGCATC CAGTTCCTCC ACCAGCACAG TGCCATCCTC CAGCCAGTCC 
TCCCACTCCA GCTCTGGGAC CCTGAGCTCT TTAGAGACAG TGTCTACTCA GGAACTCTGT 
TCTATTCCTG AGGACCAAGA ACCGGAAGAG CCTGGACCTA CTCCTTGGGC TCGGCTATGG 
GCTCTTCAGG ATGGATTCTC GAATCTAGAC TGTGTTAATG ACAACTACTG GTTCGGGAGG 
GATAAAAGCT GTGAATATTG CTTCGATGGA CCACTGTTGA AAAGGACGGA TAAGTACCGG 
ACTTACAGCA AGAAGCACTT TCGCATCTTC AGGGAAATGG GCCCTAAGAA TTGTTACATT 
GTATACCTAG AAGACCACAG TGGAAATGGA ACCTTTGTAA ATACAGAGCT TATCGGGAAA 
GGAAAACGCT GTCCTTTGAG TAACAACTCT GAAATCGCAC TTTCACTGTG TAGAAATAAA 
GTTTTTGTAT TTTTTGATCT GACTGTAGAT GACCAGTCAG TTTATCCTAA GGAATTAAGA 
GACGAATACA TCATGTCAAA AACTCTTGGA AGCGGTGCCT GTGGGGAGGT AAAGATGGCC 
TTTGAGAGGA AAACGTGTAA GAAAGTGGCC ATAAAGATCA TCAGCAAGCG GAGGTTCGCC 
CTTGGCTCGT CCAGAGAAGC TGACACAGCT CCCAGTGTGG AAACTGAAAT AGAAATTTTG 
AAGAAGCTGA ATCATCCGTG CATCATCAAG ATTAAAGATG TCTTTGATGT GGAAGATTAT 
TACATTGTTC TGGAACTGAT GGAAGGAGGA GAATTGTTTG ACCGTGTGGT GGGGAACAAA 
CGCCTGAAGG AAGCCACCTG CAAGCTCTAT TTCTACCAAA TGCTTTTAGC TGTACAGTAC 
CTTCATGAAA ATGGGATCAT ACATCGGGAC CTAAAGCCAG AGAATGTTCT TCTGTCATCT 
CAGGAAGAGG ACTGTCTTAT CAAGATCACT GATTTTGGAC AGTCCAAGAT CTTGGGGGAG 
ACCTCCCTGA TGAGGACTCT ATGTGGTACG CCCACTTATC TGGCTCCTGA GGTCCTTATC 
TCCAACGGGA CTGCTGGGTA CAGCCGGGCC GTCGACTGCT GGAGCCTAGG AGTCATTCTT 
TTCATCTGCC TAAGTGGGTA TCCACCTTTC TCTGAGCATA AGACCCAAGT GTCACTGAAG 
GATCAGATCA CCAGTGGAAA GTACAACCTT ATTCCGGAAG TCTGGACAGA TGTCTCAGAG 
AAGGCTCTGG ACCTTGTCAA GAAACTACTG GTTGTGGATC CAAAGGCCAG GCTTACCACA 
GAGGAAGCCT TAAGTCATCC TTGGCTTCAG GATGAGCACA TGAAGAAGAA GTTTCAGGAT 
CTGCTGGTGC AGGAAAAGAA CTTGGTGCCC CTCCCTCTGG CTCCTGCCCA GACTTCCGGT 
CAAAAGCGGC CCCTGGAACT GGAGGCGGAG GACGCGGAGA GCTCGAAGCG CCTGGCCGTG 
TGTAAGGCTG TGTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446129.1
CDS	96..1733
Translation	MKSHQSHGSTSSKAHDSASCSQSQGGFSQSQGTPSQLHDLSQYQGASSSSTSTVPSSSQSSHSSSGTLSSLETVSTQELCSIPEDQEPEEPGPTPWARLWALQDGFSNLDCVNDNYWFGRDKSCEYCFDGPLLKRTDKYRTYSKKHFRIFREMGPKNCYIVYLEDHSGNGTFVNTELIGKGKRCPLSNNSEIALSLCRNKVFVFFDLTVDDQSVYPKELRDEYIMSKTLGSGACGEVKMAFERKTCKKVAIKIISKRRFALGSSREADTAPSVETEIEILKKLNHPCIIKIKDVFDVEDYYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLISNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNLIPEVWTDVSEKALDLVKKLLVVDPKARLTTEEALSHPWLQDEHMKKKFQDLLVQEKNLVPLPLAPAQTSGQKRPLELEAEDAESSKRLAVCKAVL

Target ORF information:

RefSeq Version	NM_053677.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus checkpoint kinase 2 (Chek2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053677.1

ORF Insert Sequence:

ATGAAGAGTC ATCAGTCCCA CGGCAGCACC TCCTCGAAGG CTCATGACAG TGCTTCCTGT 
TCACAGTCTC AAGGCGGCTT CAGCCAGTCC CAAGGCACCC CCTCTCAGTT GCACGACCTC 
TCACAGTATC AGGGTGCATC CAGTTCCTCC ACCAGCACAG TGCCATCCTC CAGCCAGTCC 
TCCCACTCCA GCTCTGGGAC CCTGAGCTCT TTAGAGACAG TGTCTACTCA GGAACTCTGT 
TCTATTCCTG AGGACCAAGA ACCGGAAGAG CCTGGACCTA CTCCTTGGGC TCGGCTATGG 
GCTCTTCAGG ATGGATTCTC GAATCTAGAC TGTGTTAATG ACAACTACTG GTTCGGGAGG 
GATAAAAGCT GTGAATATTG CTTCGATGGA CCACTGTTGA AAAGGACGGA TAAGTACCGG 
ACTTACAGCA AGAAGCACTT TCGCATCTTC AGGGAAATGG GCCCTAAGAA TTGTTACATT 
GTATACCTAG AAGACCACAG TGGAAATGGA ACCTTTGTAA ATACAGAGCT TATCGGGAAA 
GGAAAACGCT GTCCTTTGAG TAACAACTCT GAAATCGCAC TTTCACTGTG TAGAAATAAA 
GTTTTTGTAT TTTTTGATCT GACTGTAGAT GACCAGTCAG TTTATCCTAA GGAATTAAGA 
GACGAATACA TCATGTCAAA AACTCTTGGA AGCGGTGCCT GTGGGGAGGT AAAGATGGCC 
TTTGAGAGGA AAACGTGTAA GAAAGTGGCC ATAAAGATCA TCAGCAAGCG GAGGTTCGCC 
CTTGGCTCGT CCAGAGAAGC TGACACAGCT CCCAGTGTGG AAACTGAAAT AGAAATTTTG 
AAGAAGCTGA ATCATCCGTG CATCATCAAG ATTAAAGATG TCTTTGATGT GGAAGATTAT 
TACATTGTTC TGGAACTGAT GGAAGGAGGA GAATTGTTTG ACCGTGTGGT GGGGAACAAA 
CGCCTGAAGG AAGCCACCTG CAAGCTCTAT TTCTACCAAA TGCTTTTAGC TGTACAGTAC 
CTTCATGAAA ATGGGATCAT ACATCGGGAC CTAAAGCCAG AGAATGTTCT TCTGTCATCT 
CAGGAAGAGG ACTGTCTTAT CAAGATCACT GATTTTGGAC AGTCCAAGAT CTTGGGGGAG 
ACCTCCCTGA TGAGGACTCT ATGTGGTACG CCCACTTATC TGGCTCCTGA GGTCCTTATC 
TCCAACGGGA CTGCTGGGTA CAGCCGGGCC GTCGACTGCT GGAGCCTAGG AGTCATTCTT 
TTCATCTGCC TAAGTGGGTA TCCACCTTTC TCTGAGCATA AGACCCAAGT GTCACTGAAG 
GATCAGATCA CCAGTGGAAA GTACAACCTT ATTCCGGAAG TCTGGACAGA TGTCTCAGAG 
AAGGCTCTGG ACCTTGTCAA GAAACTACTG GTTGTGGATC CAAAGGCCAG GCTTACCACA 
GAGGAAGCCT TAAGTCATCC TTGGCTTCAG GATGAGCACA TGAAGAAGAA GTTTCAGGAT 
CTGCTGGTGC AGGAAAAGAA CTTGGTGCCC CTCCCTCTGG CTCCTGCCCA GACTTCCGGT 
CAAAAGCGGC CCCTGGAACT GGAGGCGGAG GACGCGGAGA GCTCGAAGCG CCTGGCCGTG 
TGTAAGGCTG TGTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Chek2 ( XM_006249518.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006249580.1 Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa10283
Clone ID Related Accession (Same CDS sequence)	XM_006249518.3 , XM_006249519.2 , XM_006249520.3 , XM_006249521.3 , NM_053677.1
Accession Version	XM_006249518.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase Chk2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249518.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAGTC ATCAGTCCCA CGGCAGCACC TCCTCGAAGG CTCATGACAG TGCTTCCTGT 
TCACAGTCTC AAGGCGGCTT CAGCCAGTCC CAAGGCACCC CCTCTCAGTT GCACGACCTC 
TCACAGTATC AGGGTGCATC CAGTTCCTCC ACCAGCACAG TGCCATCCTC CAGCCAGTCC 
TCCCACTCCA GCTCTGGGAC CCTGAGCTCT TTAGAGACAG TGTCTACTCA GGAACTCTGT 
TCTATTCCTG AGGACCAAGA ACCGGAAGAG CCTGGACCTA CTCCTTGGGC TCGGCTATGG 
GCTCTTCAGG ATGGATTCTC GAATCTAGAC TGTGTTAATG ACAACTACTG GTTCGGGAGG 
GATAAAAGCT GTGAATATTG CTTCGATGGA CCACTGTTGA AAAGGACGGA TAAGTACCGG 
ACTTACAGCA AGAAGCACTT TCGCATCTTC AGGGAAATGG GCCCTAAGAA TTGTTACATT 
GTATACCTAG AAGACCACAG TGGAAATGGA ACCTTTGTAA ATACAGAGCT TATCGGGAAA 
GGAAAACGCT GTCCTTTGAG TAACAACTCT GAAATCGCAC TTTCACTGTG TAGAAATAAA 
GTTTTTGTAT TTTTTGATCT GACTGTAGAT GACCAGTCAG TTTATCCTAA GGAATTAAGA 
GACGAATACA TCATGTCAAA AACTCTTGGA AGCGGTGCCT GTGGGGAGGT AAAGATGGCC 
TTTGAGAGGA AAACGTGTAA GAAAGTGGCC ATAAAGATCA TCAGCAAGCG GAGGTTCGCC 
CTTGGCTCGT CCAGAGAAGC TGACACAGCT CCCAGTGTGG AAACTGAAAT AGAAATTTTG 
AAGAAGCTGA ATCATCCGTG CATCATCAAG ATTAAAGATG TCTTTGATGT GGAAGATTAT 
TACATTGTTC TGGAACTGAT GGAAGGAGGA GAATTGTTTG ACCGTGTGGT GGGGAACAAA 
CGCCTGAAGG AAGCCACCTG CAAGCTCTAT TTCTACCAAA TGCTTTTAGC TGTACAGTAC 
CTTCATGAAA ATGGGATCAT ACATCGGGAC CTAAAGCCAG AGAATGTTCT TCTGTCATCT 
CAGGAAGAGG ACTGTCTTAT CAAGATCACT GATTTTGGAC AGTCCAAGAT CTTGGGGGAG 
ACCTCCCTGA TGAGGACTCT ATGTGGTACG CCCACTTATC TGGCTCCTGA GGTCCTTATC 
TCCAACGGGA CTGCTGGGTA CAGCCGGGCC GTCGACTGCT GGAGCCTAGG AGTCATTCTT 
TTCATCTGCC TAAGTGGGTA TCCACCTTTC TCTGAGCATA AGACCCAAGT GTCACTGAAG 
GATCAGATCA CCAGTGGAAA GTACAACCTT ATTCCGGAAG TCTGGACAGA TGTCTCAGAG 
AAGGCTCTGG ACCTTGTCAA GAAACTACTG GTTGTGGATC CAAAGGCCAG GCTTACCACA 
GAGGAAGCCT TAAGTCATCC TTGGCTTCAG GATGAGCACA TGAAGAAGAA GTTTCAGGAT 
CTGCTGGTGC AGGAAAAGAA CTTGGTGCCC CTCCCTCTGG CTCCTGCCCA GACTTCCGGT 
CAAAAGCGGC CCCTGGAACT GGAGGCGGAG GACGCGGAGA GCTCGAAGCG CCTGGCCGTG 
TGTAAGGCTG TGTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006249580.1
CDS	216..1853
Translation	MKSHQSHGSTSSKAHDSASCSQSQGGFSQSQGTPSQLHDLSQYQGASSSSTSTVPSSSQSSHSSSGTLSSLETVSTQELCSIPEDQEPEEPGPTPWARLWALQDGFSNLDCVNDNYWFGRDKSCEYCFDGPLLKRTDKYRTYSKKHFRIFREMGPKNCYIVYLEDHSGNGTFVNTELIGKGKRCPLSNNSEIALSLCRNKVFVFFDLTVDDQSVYPKELRDEYIMSKTLGSGACGEVKMAFERKTCKKVAIKIISKRRFALGSSREADTAPSVETEIEILKKLNHPCIIKIKDVFDVEDYYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLISNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNLIPEVWTDVSEKALDLVKKLLVVDPKARLTTEEALSHPWLQDEHMKKKFQDLLVQEKNLVPLPLAPAQTSGQKRPLELEAEDAESSKRLAVCKAVL

Target ORF information:

RefSeq Version	XM_006249518.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249518.3

ORF Insert Sequence:

ATGAAGAGTC ATCAGTCCCA CGGCAGCACC TCCTCGAAGG CTCATGACAG TGCTTCCTGT 
TCACAGTCTC AAGGCGGCTT CAGCCAGTCC CAAGGCACCC CCTCTCAGTT GCACGACCTC 
TCACAGTATC AGGGTGCATC CAGTTCCTCC ACCAGCACAG TGCCATCCTC CAGCCAGTCC 
TCCCACTCCA GCTCTGGGAC CCTGAGCTCT TTAGAGACAG TGTCTACTCA GGAACTCTGT 
TCTATTCCTG AGGACCAAGA ACCGGAAGAG CCTGGACCTA CTCCTTGGGC TCGGCTATGG 
GCTCTTCAGG ATGGATTCTC GAATCTAGAC TGTGTTAATG ACAACTACTG GTTCGGGAGG 
GATAAAAGCT GTGAATATTG CTTCGATGGA CCACTGTTGA AAAGGACGGA TAAGTACCGG 
ACTTACAGCA AGAAGCACTT TCGCATCTTC AGGGAAATGG GCCCTAAGAA TTGTTACATT 
GTATACCTAG AAGACCACAG TGGAAATGGA ACCTTTGTAA ATACAGAGCT TATCGGGAAA 
GGAAAACGCT GTCCTTTGAG TAACAACTCT GAAATCGCAC TTTCACTGTG TAGAAATAAA 
GTTTTTGTAT TTTTTGATCT GACTGTAGAT GACCAGTCAG TTTATCCTAA GGAATTAAGA 
GACGAATACA TCATGTCAAA AACTCTTGGA AGCGGTGCCT GTGGGGAGGT AAAGATGGCC 
TTTGAGAGGA AAACGTGTAA GAAAGTGGCC ATAAAGATCA TCAGCAAGCG GAGGTTCGCC 
CTTGGCTCGT CCAGAGAAGC TGACACAGCT CCCAGTGTGG AAACTGAAAT AGAAATTTTG 
AAGAAGCTGA ATCATCCGTG CATCATCAAG ATTAAAGATG TCTTTGATGT GGAAGATTAT 
TACATTGTTC TGGAACTGAT GGAAGGAGGA GAATTGTTTG ACCGTGTGGT GGGGAACAAA 
CGCCTGAAGG AAGCCACCTG CAAGCTCTAT TTCTACCAAA TGCTTTTAGC TGTACAGTAC 
CTTCATGAAA ATGGGATCAT ACATCGGGAC CTAAAGCCAG AGAATGTTCT TCTGTCATCT 
CAGGAAGAGG ACTGTCTTAT CAAGATCACT GATTTTGGAC AGTCCAAGAT CTTGGGGGAG 
ACCTCCCTGA TGAGGACTCT ATGTGGTACG CCCACTTATC TGGCTCCTGA GGTCCTTATC 
TCCAACGGGA CTGCTGGGTA CAGCCGGGCC GTCGACTGCT GGAGCCTAGG AGTCATTCTT 
TTCATCTGCC TAAGTGGGTA TCCACCTTTC TCTGAGCATA AGACCCAAGT GTCACTGAAG 
GATCAGATCA CCAGTGGAAA GTACAACCTT ATTCCGGAAG TCTGGACAGA TGTCTCAGAG 
AAGGCTCTGG ACCTTGTCAA GAAACTACTG GTTGTGGATC CAAAGGCCAG GCTTACCACA 
GAGGAAGCCT TAAGTCATCC TTGGCTTCAG GATGAGCACA TGAAGAAGAA GTTTCAGGAT 
CTGCTGGTGC AGGAAAAGAA CTTGGTGCCC CTCCCTCTGG CTCCTGCCCA GACTTCCGGT 
CAAAAGCGGC CCCTGGAACT GGAGGCGGAG GACGCGGAGA GCTCGAAGCG CCTGGCCGTG 
TGTAAGGCTG TGTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Chek2 ( XM_006249519.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006249581.1 Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa10283
Clone ID Related Accession (Same CDS sequence)	XM_006249518.3 , XM_006249519.2 , XM_006249520.3 , XM_006249521.3 , NM_053677.1
Accession Version	XM_006249519.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase Chk2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006249519.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAGTC ATCAGTCCCA CGGCAGCACC TCCTCGAAGG CTCATGACAG TGCTTCCTGT 
TCACAGTCTC AAGGCGGCTT CAGCCAGTCC CAAGGCACCC CCTCTCAGTT GCACGACCTC 
TCACAGTATC AGGGTGCATC CAGTTCCTCC ACCAGCACAG TGCCATCCTC CAGCCAGTCC 
TCCCACTCCA GCTCTGGGAC CCTGAGCTCT TTAGAGACAG TGTCTACTCA GGAACTCTGT 
TCTATTCCTG AGGACCAAGA ACCGGAAGAG CCTGGACCTA CTCCTTGGGC TCGGCTATGG 
GCTCTTCAGG ATGGATTCTC GAATCTAGAC TGTGTTAATG ACAACTACTG GTTCGGGAGG 
GATAAAAGCT GTGAATATTG CTTCGATGGA CCACTGTTGA AAAGGACGGA TAAGTACCGG 
ACTTACAGCA AGAAGCACTT TCGCATCTTC AGGGAAATGG GCCCTAAGAA TTGTTACATT 
GTATACCTAG AAGACCACAG TGGAAATGGA ACCTTTGTAA ATACAGAGCT TATCGGGAAA 
GGAAAACGCT GTCCTTTGAG TAACAACTCT GAAATCGCAC TTTCACTGTG TAGAAATAAA 
GTTTTTGTAT TTTTTGATCT GACTGTAGAT GACCAGTCAG TTTATCCTAA GGAATTAAGA 
GACGAATACA TCATGTCAAA AACTCTTGGA AGCGGTGCCT GTGGGGAGGT AAAGATGGCC 
TTTGAGAGGA AAACGTGTAA GAAAGTGGCC ATAAAGATCA TCAGCAAGCG GAGGTTCGCC 
CTTGGCTCGT CCAGAGAAGC TGACACAGCT CCCAGTGTGG AAACTGAAAT AGAAATTTTG 
AAGAAGCTGA ATCATCCGTG CATCATCAAG ATTAAAGATG TCTTTGATGT GGAAGATTAT 
TACATTGTTC TGGAACTGAT GGAAGGAGGA GAATTGTTTG ACCGTGTGGT GGGGAACAAA 
CGCCTGAAGG AAGCCACCTG CAAGCTCTAT TTCTACCAAA TGCTTTTAGC TGTACAGTAC 
CTTCATGAAA ATGGGATCAT ACATCGGGAC CTAAAGCCAG AGAATGTTCT TCTGTCATCT 
CAGGAAGAGG ACTGTCTTAT CAAGATCACT GATTTTGGAC AGTCCAAGAT CTTGGGGGAG 
ACCTCCCTGA TGAGGACTCT ATGTGGTACG CCCACTTATC TGGCTCCTGA GGTCCTTATC 
TCCAACGGGA CTGCTGGGTA CAGCCGGGCC GTCGACTGCT GGAGCCTAGG AGTCATTCTT 
TTCATCTGCC TAAGTGGGTA TCCACCTTTC TCTGAGCATA AGACCCAAGT GTCACTGAAG 
GATCAGATCA CCAGTGGAAA GTACAACCTT ATTCCGGAAG TCTGGACAGA TGTCTCAGAG 
AAGGCTCTGG ACCTTGTCAA GAAACTACTG GTTGTGGATC CAAAGGCCAG GCTTACCACA 
GAGGAAGCCT TAAGTCATCC TTGGCTTCAG GATGAGCACA TGAAGAAGAA GTTTCAGGAT 
CTGCTGGTGC AGGAAAAGAA CTTGGTGCCC CTCCCTCTGG CTCCTGCCCA GACTTCCGGT 
CAAAAGCGGC CCCTGGAACT GGAGGCGGAG GACGCGGAGA GCTCGAAGCG CCTGGCCGTG 
TGTAAGGCTG TGTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006249581.1
CDS	89..1726
Translation	MKSHQSHGSTSSKAHDSASCSQSQGGFSQSQGTPSQLHDLSQYQGASSSSTSTVPSSSQSSHSSSGTLSSLETVSTQELCSIPEDQEPEEPGPTPWARLWALQDGFSNLDCVNDNYWFGRDKSCEYCFDGPLLKRTDKYRTYSKKHFRIFREMGPKNCYIVYLEDHSGNGTFVNTELIGKGKRCPLSNNSEIALSLCRNKVFVFFDLTVDDQSVYPKELRDEYIMSKTLGSGACGEVKMAFERKTCKKVAIKIISKRRFALGSSREADTAPSVETEIEILKKLNHPCIIKIKDVFDVEDYYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLISNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNLIPEVWTDVSEKALDLVKKLLVVDPKARLTTEEALSHPWLQDEHMKKKFQDLLVQEKNLVPLPLAPAQTSGQKRPLELEAEDAESSKRLAVCKAVL

Target ORF information:

RefSeq Version	XM_006249519.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249519.2

ORF Insert Sequence:

ATGAAGAGTC ATCAGTCCCA CGGCAGCACC TCCTCGAAGG CTCATGACAG TGCTTCCTGT 
TCACAGTCTC AAGGCGGCTT CAGCCAGTCC CAAGGCACCC CCTCTCAGTT GCACGACCTC 
TCACAGTATC AGGGTGCATC CAGTTCCTCC ACCAGCACAG TGCCATCCTC CAGCCAGTCC 
TCCCACTCCA GCTCTGGGAC CCTGAGCTCT TTAGAGACAG TGTCTACTCA GGAACTCTGT 
TCTATTCCTG AGGACCAAGA ACCGGAAGAG CCTGGACCTA CTCCTTGGGC TCGGCTATGG 
GCTCTTCAGG ATGGATTCTC GAATCTAGAC TGTGTTAATG ACAACTACTG GTTCGGGAGG 
GATAAAAGCT GTGAATATTG CTTCGATGGA CCACTGTTGA AAAGGACGGA TAAGTACCGG 
ACTTACAGCA AGAAGCACTT TCGCATCTTC AGGGAAATGG GCCCTAAGAA TTGTTACATT 
GTATACCTAG AAGACCACAG TGGAAATGGA ACCTTTGTAA ATACAGAGCT TATCGGGAAA 
GGAAAACGCT GTCCTTTGAG TAACAACTCT GAAATCGCAC TTTCACTGTG TAGAAATAAA 
GTTTTTGTAT TTTTTGATCT GACTGTAGAT GACCAGTCAG TTTATCCTAA GGAATTAAGA 
GACGAATACA TCATGTCAAA AACTCTTGGA AGCGGTGCCT GTGGGGAGGT AAAGATGGCC 
TTTGAGAGGA AAACGTGTAA GAAAGTGGCC ATAAAGATCA TCAGCAAGCG GAGGTTCGCC 
CTTGGCTCGT CCAGAGAAGC TGACACAGCT CCCAGTGTGG AAACTGAAAT AGAAATTTTG 
AAGAAGCTGA ATCATCCGTG CATCATCAAG ATTAAAGATG TCTTTGATGT GGAAGATTAT 
TACATTGTTC TGGAACTGAT GGAAGGAGGA GAATTGTTTG ACCGTGTGGT GGGGAACAAA 
CGCCTGAAGG AAGCCACCTG CAAGCTCTAT TTCTACCAAA TGCTTTTAGC TGTACAGTAC 
CTTCATGAAA ATGGGATCAT ACATCGGGAC CTAAAGCCAG AGAATGTTCT TCTGTCATCT 
CAGGAAGAGG ACTGTCTTAT CAAGATCACT GATTTTGGAC AGTCCAAGAT CTTGGGGGAG 
ACCTCCCTGA TGAGGACTCT ATGTGGTACG CCCACTTATC TGGCTCCTGA GGTCCTTATC 
TCCAACGGGA CTGCTGGGTA CAGCCGGGCC GTCGACTGCT GGAGCCTAGG AGTCATTCTT 
TTCATCTGCC TAAGTGGGTA TCCACCTTTC TCTGAGCATA AGACCCAAGT GTCACTGAAG 
GATCAGATCA CCAGTGGAAA GTACAACCTT ATTCCGGAAG TCTGGACAGA TGTCTCAGAG 
AAGGCTCTGG ACCTTGTCAA GAAACTACTG GTTGTGGATC CAAAGGCCAG GCTTACCACA 
GAGGAAGCCT TAAGTCATCC TTGGCTTCAG GATGAGCACA TGAAGAAGAA GTTTCAGGAT 
CTGCTGGTGC AGGAAAAGAA CTTGGTGCCC CTCCCTCTGG CTCCTGCCCA GACTTCCGGT 
CAAAAGCGGC CCCTGGAACT GGAGGCGGAG GACGCGGAGA GCTCGAAGCG CCTGGCCGTG 
TGTAAGGCTG TGTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Chek2 ( XM_006249520.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006249582.1 Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X3, mRNA.

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CloneID	ORa10283
Clone ID Related Accession (Same CDS sequence)	XM_006249518.3 , XM_006249519.2 , XM_006249520.3 , XM_006249521.3 , NM_053677.1
Accession Version	XM_006249520.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase Chk2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249520.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAGTC ATCAGTCCCA CGGCAGCACC TCCTCGAAGG CTCATGACAG TGCTTCCTGT 
TCACAGTCTC AAGGCGGCTT CAGCCAGTCC CAAGGCACCC CCTCTCAGTT GCACGACCTC 
TCACAGTATC AGGGTGCATC CAGTTCCTCC ACCAGCACAG TGCCATCCTC CAGCCAGTCC 
TCCCACTCCA GCTCTGGGAC CCTGAGCTCT TTAGAGACAG TGTCTACTCA GGAACTCTGT 
TCTATTCCTG AGGACCAAGA ACCGGAAGAG CCTGGACCTA CTCCTTGGGC TCGGCTATGG 
GCTCTTCAGG ATGGATTCTC GAATCTAGAC TGTGTTAATG ACAACTACTG GTTCGGGAGG 
GATAAAAGCT GTGAATATTG CTTCGATGGA CCACTGTTGA AAAGGACGGA TAAGTACCGG 
ACTTACAGCA AGAAGCACTT TCGCATCTTC AGGGAAATGG GCCCTAAGAA TTGTTACATT 
GTATACCTAG AAGACCACAG TGGAAATGGA ACCTTTGTAA ATACAGAGCT TATCGGGAAA 
GGAAAACGCT GTCCTTTGAG TAACAACTCT GAAATCGCAC TTTCACTGTG TAGAAATAAA 
GTTTTTGTAT TTTTTGATCT GACTGTAGAT GACCAGTCAG TTTATCCTAA GGAATTAAGA 
GACGAATACA TCATGTCAAA AACTCTTGGA AGCGGTGCCT GTGGGGAGGT AAAGATGGCC 
TTTGAGAGGA AAACGTGTAA GAAAGTGGCC ATAAAGATCA TCAGCAAGCG GAGGTTCGCC 
CTTGGCTCGT CCAGAGAAGC TGACACAGCT CCCAGTGTGG AAACTGAAAT AGAAATTTTG 
AAGAAGCTGA ATCATCCGTG CATCATCAAG ATTAAAGATG TCTTTGATGT GGAAGATTAT 
TACATTGTTC TGGAACTGAT GGAAGGAGGA GAATTGTTTG ACCGTGTGGT GGGGAACAAA 
CGCCTGAAGG AAGCCACCTG CAAGCTCTAT TTCTACCAAA TGCTTTTAGC TGTACAGTAC 
CTTCATGAAA ATGGGATCAT ACATCGGGAC CTAAAGCCAG AGAATGTTCT TCTGTCATCT 
CAGGAAGAGG ACTGTCTTAT CAAGATCACT GATTTTGGAC AGTCCAAGAT CTTGGGGGAG 
ACCTCCCTGA TGAGGACTCT ATGTGGTACG CCCACTTATC TGGCTCCTGA GGTCCTTATC 
TCCAACGGGA CTGCTGGGTA CAGCCGGGCC GTCGACTGCT GGAGCCTAGG AGTCATTCTT 
TTCATCTGCC TAAGTGGGTA TCCACCTTTC TCTGAGCATA AGACCCAAGT GTCACTGAAG 
GATCAGATCA CCAGTGGAAA GTACAACCTT ATTCCGGAAG TCTGGACAGA TGTCTCAGAG 
AAGGCTCTGG ACCTTGTCAA GAAACTACTG GTTGTGGATC CAAAGGCCAG GCTTACCACA 
GAGGAAGCCT TAAGTCATCC TTGGCTTCAG GATGAGCACA TGAAGAAGAA GTTTCAGGAT 
CTGCTGGTGC AGGAAAAGAA CTTGGTGCCC CTCCCTCTGG CTCCTGCCCA GACTTCCGGT 
CAAAAGCGGC CCCTGGAACT GGAGGCGGAG GACGCGGAGA GCTCGAAGCG CCTGGCCGTG 
TGTAAGGCTG TGTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006249582.1
CDS	147..1784
Translation	MKSHQSHGSTSSKAHDSASCSQSQGGFSQSQGTPSQLHDLSQYQGASSSSTSTVPSSSQSSHSSSGTLSSLETVSTQELCSIPEDQEPEEPGPTPWARLWALQDGFSNLDCVNDNYWFGRDKSCEYCFDGPLLKRTDKYRTYSKKHFRIFREMGPKNCYIVYLEDHSGNGTFVNTELIGKGKRCPLSNNSEIALSLCRNKVFVFFDLTVDDQSVYPKELRDEYIMSKTLGSGACGEVKMAFERKTCKKVAIKIISKRRFALGSSREADTAPSVETEIEILKKLNHPCIIKIKDVFDVEDYYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLISNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNLIPEVWTDVSEKALDLVKKLLVVDPKARLTTEEALSHPWLQDEHMKKKFQDLLVQEKNLVPLPLAPAQTSGQKRPLELEAEDAESSKRLAVCKAVL

Target ORF information:

RefSeq Version	XM_006249520.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249520.3

ORF Insert Sequence:

ATGAAGAGTC ATCAGTCCCA CGGCAGCACC TCCTCGAAGG CTCATGACAG TGCTTCCTGT 
TCACAGTCTC AAGGCGGCTT CAGCCAGTCC CAAGGCACCC CCTCTCAGTT GCACGACCTC 
TCACAGTATC AGGGTGCATC CAGTTCCTCC ACCAGCACAG TGCCATCCTC CAGCCAGTCC 
TCCCACTCCA GCTCTGGGAC CCTGAGCTCT TTAGAGACAG TGTCTACTCA GGAACTCTGT 
TCTATTCCTG AGGACCAAGA ACCGGAAGAG CCTGGACCTA CTCCTTGGGC TCGGCTATGG 
GCTCTTCAGG ATGGATTCTC GAATCTAGAC TGTGTTAATG ACAACTACTG GTTCGGGAGG 
GATAAAAGCT GTGAATATTG CTTCGATGGA CCACTGTTGA AAAGGACGGA TAAGTACCGG 
ACTTACAGCA AGAAGCACTT TCGCATCTTC AGGGAAATGG GCCCTAAGAA TTGTTACATT 
GTATACCTAG AAGACCACAG TGGAAATGGA ACCTTTGTAA ATACAGAGCT TATCGGGAAA 
GGAAAACGCT GTCCTTTGAG TAACAACTCT GAAATCGCAC TTTCACTGTG TAGAAATAAA 
GTTTTTGTAT TTTTTGATCT GACTGTAGAT GACCAGTCAG TTTATCCTAA GGAATTAAGA 
GACGAATACA TCATGTCAAA AACTCTTGGA AGCGGTGCCT GTGGGGAGGT AAAGATGGCC 
TTTGAGAGGA AAACGTGTAA GAAAGTGGCC ATAAAGATCA TCAGCAAGCG GAGGTTCGCC 
CTTGGCTCGT CCAGAGAAGC TGACACAGCT CCCAGTGTGG AAACTGAAAT AGAAATTTTG 
AAGAAGCTGA ATCATCCGTG CATCATCAAG ATTAAAGATG TCTTTGATGT GGAAGATTAT 
TACATTGTTC TGGAACTGAT GGAAGGAGGA GAATTGTTTG ACCGTGTGGT GGGGAACAAA 
CGCCTGAAGG AAGCCACCTG CAAGCTCTAT TTCTACCAAA TGCTTTTAGC TGTACAGTAC 
CTTCATGAAA ATGGGATCAT ACATCGGGAC CTAAAGCCAG AGAATGTTCT TCTGTCATCT 
CAGGAAGAGG ACTGTCTTAT CAAGATCACT GATTTTGGAC AGTCCAAGAT CTTGGGGGAG 
ACCTCCCTGA TGAGGACTCT ATGTGGTACG CCCACTTATC TGGCTCCTGA GGTCCTTATC 
TCCAACGGGA CTGCTGGGTA CAGCCGGGCC GTCGACTGCT GGAGCCTAGG AGTCATTCTT 
TTCATCTGCC TAAGTGGGTA TCCACCTTTC TCTGAGCATA AGACCCAAGT GTCACTGAAG 
GATCAGATCA CCAGTGGAAA GTACAACCTT ATTCCGGAAG TCTGGACAGA TGTCTCAGAG 
AAGGCTCTGG ACCTTGTCAA GAAACTACTG GTTGTGGATC CAAAGGCCAG GCTTACCACA 
GAGGAAGCCT TAAGTCATCC TTGGCTTCAG GATGAGCACA TGAAGAAGAA GTTTCAGGAT 
CTGCTGGTGC AGGAAAAGAA CTTGGTGCCC CTCCCTCTGG CTCCTGCCCA GACTTCCGGT 
CAAAAGCGGC CCCTGGAACT GGAGGCGGAG GACGCGGAGA GCTCGAAGCG CCTGGCCGTG 
TGTAAGGCTG TGTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Chek2 ( XM_006249521.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006249583.1 Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa10283
Clone ID Related Accession (Same CDS sequence)	XM_006249518.3 , XM_006249519.2 , XM_006249520.3 , XM_006249521.3 , NM_053677.1
Accession Version	XM_006249521.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase Chk2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249521.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAGTC ATCAGTCCCA CGGCAGCACC TCCTCGAAGG CTCATGACAG TGCTTCCTGT 
TCACAGTCTC AAGGCGGCTT CAGCCAGTCC CAAGGCACCC CCTCTCAGTT GCACGACCTC 
TCACAGTATC AGGGTGCATC CAGTTCCTCC ACCAGCACAG TGCCATCCTC CAGCCAGTCC 
TCCCACTCCA GCTCTGGGAC CCTGAGCTCT TTAGAGACAG TGTCTACTCA GGAACTCTGT 
TCTATTCCTG AGGACCAAGA ACCGGAAGAG CCTGGACCTA CTCCTTGGGC TCGGCTATGG 
GCTCTTCAGG ATGGATTCTC GAATCTAGAC TGTGTTAATG ACAACTACTG GTTCGGGAGG 
GATAAAAGCT GTGAATATTG CTTCGATGGA CCACTGTTGA AAAGGACGGA TAAGTACCGG 
ACTTACAGCA AGAAGCACTT TCGCATCTTC AGGGAAATGG GCCCTAAGAA TTGTTACATT 
GTATACCTAG AAGACCACAG TGGAAATGGA ACCTTTGTAA ATACAGAGCT TATCGGGAAA 
GGAAAACGCT GTCCTTTGAG TAACAACTCT GAAATCGCAC TTTCACTGTG TAGAAATAAA 
GTTTTTGTAT TTTTTGATCT GACTGTAGAT GACCAGTCAG TTTATCCTAA GGAATTAAGA 
GACGAATACA TCATGTCAAA AACTCTTGGA AGCGGTGCCT GTGGGGAGGT AAAGATGGCC 
TTTGAGAGGA AAACGTGTAA GAAAGTGGCC ATAAAGATCA TCAGCAAGCG GAGGTTCGCC 
CTTGGCTCGT CCAGAGAAGC TGACACAGCT CCCAGTGTGG AAACTGAAAT AGAAATTTTG 
AAGAAGCTGA ATCATCCGTG CATCATCAAG ATTAAAGATG TCTTTGATGT GGAAGATTAT 
TACATTGTTC TGGAACTGAT GGAAGGAGGA GAATTGTTTG ACCGTGTGGT GGGGAACAAA 
CGCCTGAAGG AAGCCACCTG CAAGCTCTAT TTCTACCAAA TGCTTTTAGC TGTACAGTAC 
CTTCATGAAA ATGGGATCAT ACATCGGGAC CTAAAGCCAG AGAATGTTCT TCTGTCATCT 
CAGGAAGAGG ACTGTCTTAT CAAGATCACT GATTTTGGAC AGTCCAAGAT CTTGGGGGAG 
ACCTCCCTGA TGAGGACTCT ATGTGGTACG CCCACTTATC TGGCTCCTGA GGTCCTTATC 
TCCAACGGGA CTGCTGGGTA CAGCCGGGCC GTCGACTGCT GGAGCCTAGG AGTCATTCTT 
TTCATCTGCC TAAGTGGGTA TCCACCTTTC TCTGAGCATA AGACCCAAGT GTCACTGAAG 
GATCAGATCA CCAGTGGAAA GTACAACCTT ATTCCGGAAG TCTGGACAGA TGTCTCAGAG 
AAGGCTCTGG ACCTTGTCAA GAAACTACTG GTTGTGGATC CAAAGGCCAG GCTTACCACA 
GAGGAAGCCT TAAGTCATCC TTGGCTTCAG GATGAGCACA TGAAGAAGAA GTTTCAGGAT 
CTGCTGGTGC AGGAAAAGAA CTTGGTGCCC CTCCCTCTGG CTCCTGCCCA GACTTCCGGT 
CAAAAGCGGC CCCTGGAACT GGAGGCGGAG GACGCGGAGA GCTCGAAGCG CCTGGCCGTG 
TGTAAGGCTG TGTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006249583.1
CDS	31..1668
Translation	MKSHQSHGSTSSKAHDSASCSQSQGGFSQSQGTPSQLHDLSQYQGASSSSTSTVPSSSQSSHSSSGTLSSLETVSTQELCSIPEDQEPEEPGPTPWARLWALQDGFSNLDCVNDNYWFGRDKSCEYCFDGPLLKRTDKYRTYSKKHFRIFREMGPKNCYIVYLEDHSGNGTFVNTELIGKGKRCPLSNNSEIALSLCRNKVFVFFDLTVDDQSVYPKELRDEYIMSKTLGSGACGEVKMAFERKTCKKVAIKIISKRRFALGSSREADTAPSVETEIEILKKLNHPCIIKIKDVFDVEDYYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLISNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNLIPEVWTDVSEKALDLVKKLLVVDPKARLTTEEALSHPWLQDEHMKKKFQDLLVQEKNLVPLPLAPAQTSGQKRPLELEAEDAESSKRLAVCKAVL

Target ORF information:

RefSeq Version	XM_006249521.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249521.3

ORF Insert Sequence:

ATGAAGAGTC ATCAGTCCCA CGGCAGCACC TCCTCGAAGG CTCATGACAG TGCTTCCTGT 
TCACAGTCTC AAGGCGGCTT CAGCCAGTCC CAAGGCACCC CCTCTCAGTT GCACGACCTC 
TCACAGTATC AGGGTGCATC CAGTTCCTCC ACCAGCACAG TGCCATCCTC CAGCCAGTCC 
TCCCACTCCA GCTCTGGGAC CCTGAGCTCT TTAGAGACAG TGTCTACTCA GGAACTCTGT 
TCTATTCCTG AGGACCAAGA ACCGGAAGAG CCTGGACCTA CTCCTTGGGC TCGGCTATGG 
GCTCTTCAGG ATGGATTCTC GAATCTAGAC TGTGTTAATG ACAACTACTG GTTCGGGAGG 
GATAAAAGCT GTGAATATTG CTTCGATGGA CCACTGTTGA AAAGGACGGA TAAGTACCGG 
ACTTACAGCA AGAAGCACTT TCGCATCTTC AGGGAAATGG GCCCTAAGAA TTGTTACATT 
GTATACCTAG AAGACCACAG TGGAAATGGA ACCTTTGTAA ATACAGAGCT TATCGGGAAA 
GGAAAACGCT GTCCTTTGAG TAACAACTCT GAAATCGCAC TTTCACTGTG TAGAAATAAA 
GTTTTTGTAT TTTTTGATCT GACTGTAGAT GACCAGTCAG TTTATCCTAA GGAATTAAGA 
GACGAATACA TCATGTCAAA AACTCTTGGA AGCGGTGCCT GTGGGGAGGT AAAGATGGCC 
TTTGAGAGGA AAACGTGTAA GAAAGTGGCC ATAAAGATCA TCAGCAAGCG GAGGTTCGCC 
CTTGGCTCGT CCAGAGAAGC TGACACAGCT CCCAGTGTGG AAACTGAAAT AGAAATTTTG 
AAGAAGCTGA ATCATCCGTG CATCATCAAG ATTAAAGATG TCTTTGATGT GGAAGATTAT 
TACATTGTTC TGGAACTGAT GGAAGGAGGA GAATTGTTTG ACCGTGTGGT GGGGAACAAA 
CGCCTGAAGG AAGCCACCTG CAAGCTCTAT TTCTACCAAA TGCTTTTAGC TGTACAGTAC 
CTTCATGAAA ATGGGATCAT ACATCGGGAC CTAAAGCCAG AGAATGTTCT TCTGTCATCT 
CAGGAAGAGG ACTGTCTTAT CAAGATCACT GATTTTGGAC AGTCCAAGAT CTTGGGGGAG 
ACCTCCCTGA TGAGGACTCT ATGTGGTACG CCCACTTATC TGGCTCCTGA GGTCCTTATC 
TCCAACGGGA CTGCTGGGTA CAGCCGGGCC GTCGACTGCT GGAGCCTAGG AGTCATTCTT 
TTCATCTGCC TAAGTGGGTA TCCACCTTTC TCTGAGCATA AGACCCAAGT GTCACTGAAG 
GATCAGATCA CCAGTGGAAA GTACAACCTT ATTCCGGAAG TCTGGACAGA TGTCTCAGAG 
AAGGCTCTGG ACCTTGTCAA GAAACTACTG GTTGTGGATC CAAAGGCCAG GCTTACCACA 
GAGGAAGCCT TAAGTCATCC TTGGCTTCAG GATGAGCACA TGAAGAAGAA GTTTCAGGAT 
CTGCTGGTGC AGGAAAAGAA CTTGGTGCCC CTCCCTCTGG CTCCTGCCCA GACTTCCGGT 
CAAAAGCGGC CCCTGGAACT GGAGGCGGAG GACGCGGAGA GCTCGAAGCG CCTGGCCGTG 
TGTAAGGCTG TGTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Chek2 ( XM_008769308.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008767530.1 Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa43925
Clone ID Related Accession (Same CDS sequence)	XM_008769308.2
Accession Version	XM_008769308.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase Chk2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008769308.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAGTC ATCAGTCCCA CGGCAGCACC TCCTCGAAGG CTCATGACAG TGCTTCCTGT 
TCACAGTCTC AAGGCGGCTT CAGCCAGTCC CAAGGCACCC CCTCTCAGTT GCACGACCTC 
TCACAGTATC AGGGTGCATC CAGTTCCTCC ACCAGCACAG TGCCATCCTC CAGCCAGTCC 
TCCCACTCCA GCTCTGGGAC CCTGAGCTCT TTAGAGACAG TGTCTACTCA GGAACTCTGT 
TCTATTCCTG AGGACCAAGA ACCGGAAGAG CCTGGACCTA CTCCTTGGGC TCGGCTATGG 
GCTCTTCAGG ATGGATTCTC GAATCTAGAC TGTGTTAATG ACAACTACTG GTTCGGGAGG 
GATAAAAGCT GTGAATATTG CTTCGATGGA CCACTGTTGA AAAGGACGGA TAAGTACCGG 
ACTTACAGCA AGAAGCACTT TCGCATCTTC AGGGAAATGG GCCCTAAGAA TTGTTACATT 
GTATACCTAG AAGACCACAG TGGAAATGGA ACCTTTGTAA ATACAGAGCT TATCGGGAAA 
GGAAAACGCT GTCCTTTGAG TAACAACTCT GAAATCGCAC TTTCACTGTG TAGAAATAAA 
GTTTTTGTAT TTTTTGATCT GACTGTAGAT GACCAGTCAG TTTATCCTAA GGAATTAAGA 
GACGAATACA TCATGTCAAA AACTCTTGGA AGCGGTGCCT GTGGGGAGGT AAAGATGGCC 
TTTGAGAGGA AAACGTGTAA GAAAGTGGCC ATAAAGATCA TCAGCAAGCG GAGGTTCGCC 
CTTGGCTCGT CCAGAGAAGC TGACACAGCT CCCAGTGTGG AAACTGAAAT AGAAATTTTG 
AAGAAGCTGA ATCATCCGTG CATCATCAAG ATTAAAGATG TCTTTGATGT GGAAGATTAT 
TACATTGTTC TGGAACTGAT GGAAGGAGGA GAATTGTTTG ACCGTGTGGT GGGGAACAAA 
CGCCTGAAGG AAGCCACCTG CAAGCTCTAT TTCTACCAAA TGCTTTTAGC TGTACAGTAC 
CTTCATGAAA ATGGGATCAT ACATCGGGAC CTAAAGCCAG AGAATGTTCT TCTGTCATCT 
CAGGAAGAGG ACTGTCTTAT CAAGATCACT GATTTTGGAC AGTCCAAGAT CTTGGGGGAG 
ACCTCCCTGA TGAGGACTCT ATGTGGTACG CCCACTTATC TGGCTCCTGA GGTCCTTATC 
TCCAACGGGA CTGCTGGGTA CAGCCGGGCC GTCGACTGCT GGAGCCTAGG AGTCATTCTT 
TTCATCTGCC TAAGTGGGTA TCCACCTTTC TCTGAGCATA AGACCCAAGT GTCACTGAAG 
GATCAGATCA CCAGTGGAAA GTACAACCTT ATTCCGGAAG TCTGGACAGA TGTCTCAGAG 
AAGGGTATGG ATACGAAAGG GTTACAGGCG TCTGGTTTAA CTGACGTGTG GGTGTCCTGT 
TGGTGGGAGC GTCTCCTCAG ACTGCTGGTT TTCTCCCATC TGGTCATTCT GTTGCTTTGC 
ACCACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008767530.1
CDS	89..1597
Translation	MKSHQSHGSTSSKAHDSASCSQSQGGFSQSQGTPSQLHDLSQYQGASSSSTSTVPSSSQSSHSSSGTLSSLETVSTQELCSIPEDQEPEEPGPTPWARLWALQDGFSNLDCVNDNYWFGRDKSCEYCFDGPLLKRTDKYRTYSKKHFRIFREMGPKNCYIVYLEDHSGNGTFVNTELIGKGKRCPLSNNSEIALSLCRNKVFVFFDLTVDDQSVYPKELRDEYIMSKTLGSGACGEVKMAFERKTCKKVAIKIISKRRFALGSSREADTAPSVETEIEILKKLNHPCIIKIKDVFDVEDYYIVLELMEGGELFDRVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGQSKILGETSLMRTLCGTPTYLAPEVLISNGTAGYSRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYNLIPEVWTDVSEKGMDTKGLQASGLTDVWVSCWWERLLRLLVFSHLVILLLCTT

Target ORF information:

RefSeq Version	XM_008769308.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus checkpoint kinase 2 (Chek2), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008769308.2

ORF Insert Sequence:

ATGAAGAGTC ATCAGTCCCA CGGCAGCACC TCCTCGAAGG CTCATGACAG TGCTTCCTGT 
TCACAGTCTC AAGGCGGCTT CAGCCAGTCC CAAGGCACCC CCTCTCAGTT GCACGACCTC 
TCACAGTATC AGGGTGCATC CAGTTCCTCC ACCAGCACAG TGCCATCCTC CAGCCAGTCC 
TCCCACTCCA GCTCTGGGAC CCTGAGCTCT TTAGAGACAG TGTCTACTCA GGAACTCTGT 
TCTATTCCTG AGGACCAAGA ACCGGAAGAG CCTGGACCTA CTCCTTGGGC TCGGCTATGG 
GCTCTTCAGG ATGGATTCTC GAATCTAGAC TGTGTTAATG ACAACTACTG GTTCGGGAGG 
GATAAAAGCT GTGAATATTG CTTCGATGGA CCACTGTTGA AAAGGACGGA TAAGTACCGG 
ACTTACAGCA AGAAGCACTT TCGCATCTTC AGGGAAATGG GCCCTAAGAA TTGTTACATT 
GTATACCTAG AAGACCACAG TGGAAATGGA ACCTTTGTAA ATACAGAGCT TATCGGGAAA 
GGAAAACGCT GTCCTTTGAG TAACAACTCT GAAATCGCAC TTTCACTGTG TAGAAATAAA 
GTTTTTGTAT TTTTTGATCT GACTGTAGAT GACCAGTCAG TTTATCCTAA GGAATTAAGA 
GACGAATACA TCATGTCAAA AACTCTTGGA AGCGGTGCCT GTGGGGAGGT AAAGATGGCC 
TTTGAGAGGA AAACGTGTAA GAAAGTGGCC ATAAAGATCA TCAGCAAGCG GAGGTTCGCC 
CTTGGCTCGT CCAGAGAAGC TGACACAGCT CCCAGTGTGG AAACTGAAAT AGAAATTTTG 
AAGAAGCTGA ATCATCCGTG CATCATCAAG ATTAAAGATG TCTTTGATGT GGAAGATTAT 
TACATTGTTC TGGAACTGAT GGAAGGAGGA GAATTGTTTG ACCGTGTGGT GGGGAACAAA 
CGCCTGAAGG AAGCCACCTG CAAGCTCTAT TTCTACCAAA TGCTTTTAGC TGTACAGTAC 
CTTCATGAAA ATGGGATCAT ACATCGGGAC CTAAAGCCAG AGAATGTTCT TCTGTCATCT 
CAGGAAGAGG ACTGTCTTAT CAAGATCACT GATTTTGGAC AGTCCAAGAT CTTGGGGGAG 
ACCTCCCTGA TGAGGACTCT ATGTGGTACG CCCACTTATC TGGCTCCTGA GGTCCTTATC 
TCCAACGGGA CTGCTGGGTA CAGCCGGGCC GTCGACTGCT GGAGCCTAGG AGTCATTCTT 
TTCATCTGCC TAAGTGGGTA TCCACCTTTC TCTGAGCATA AGACCCAAGT GTCACTGAAG 
GATCAGATCA CCAGTGGAAA GTACAACCTT ATTCCGGAAG TCTGGACAGA TGTCTCAGAG 
AAGGGTATGG ATACGAAAGG GTTACAGGCG TCTGGTTTAA CTGACGTGTG GGTGTCCTGT 
TGGTGGGAGC GTCTCCTCAG ACTGCTGGTT TTCTCCCATC TGGTCATTCT GTTGCTTTGC 
ACCACTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Bisphenol A induces oxidative stress-associated DNA damage in INS-1 cells.
Mutation research. Genetic toxicology and environmental mutagenesis76929-33(2014 Jul)
Xin F,Jiang L,Liu X,Geng C,Wang W,Zhong L,Yang G,Chen M

Premature cardiac senescence in DahlS.Z-Lepr(fa)/Lepr(fa) rats as a new animal model of metabolic syndrome.
Nagoya journal of medical science76(1-2)35-49(2014 Feb)
Takahashi K,Takatsu M,Hattori T,Murase T,Ohura S,Takeshita Y,Watanabe S,Murohara T,Nagata K

PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair.
Proceedings of the National Academy of Sciences of the United States of America111(7)E728-37(2014 Feb)
Khoury-Haddad H,Guttmann-Raviv N,Ipenberg I,Huggins D,Jeyasekharan AD,Ayoub N

Nek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblasts.
Molecular and cellular biology32(19)3963-77(2012 Oct)
Nguyen CL,Possemato R,Bauerlein EL,Xie A,Scully R,Hahn WC

Cellular distribution of cell cycle-related molecules in the renal tubules of rats treated with renal carcinogens for 28 days: relationship between cell cycle aberration and carcinogenesis.
Archives of toxicology86(9)1453-64(2012 Sep)
Taniai E,Hayashi H,Yafune A,Watanabe M,Akane H,Suzuki K,Mitsumori K,Shibutani M

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Chek2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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