Gene Symbol | ATG7 |
Entrez Gene ID | 74244 |
Full Name | autophagy related 7 |
Synonyms | 1810013K23Rik,Agp7,Apg7l,Atg7l,Gm21553 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(House mouse) |
Genome | |
Summary | This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]. |