Med26 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Med26
Entrez Gene ID	70625
Full Name	mediator complex subunit 26
Synonyms	5730493L18Rik,AI414941,AW495270,Crsp7
General protein information	Preferred Names mediator complex subunit 26 Names mediator of RNA polymerase II transcription subunit 26 CRSP complex subunit 7 cofactor required for Sp1 transcriptional activation subunit 7 cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 B3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_027485.4	NP_081761.2	mediator of RNA polymerase II transcription subunit 26
XM_006509739.4	XP_006509802.1	mediator of RNA polymerase II transcription subunit 26 isoform X1
XM_006509739.3	XP_006509802.1	mediator of RNA polymerase II transcription subunit 26 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	MED26	NP_001092358.1
Gallus gallus (chicken)	MED26	XP_004948991.1
Danio rerio (zebrafish)	crsp7	NP_998224.1
Homo sapiens (human)	MED26	NP_004822.2
Pan troglodytes (chimpanzee)	MED26	XP_003953452.1
Xenopus tropicalis (tropical clawed frog)	med26	NP_001016996.1
Canis lupus familiaris (dog)	MED26	XP_541963.3
Mus musculus (house mouse)	Med26	NP_081761.2
Rattus norvegicus (Norway rat)	Med26	NP_001100770.2

Gene Ontology
Bibliography

Related articles in PubMed

MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex.
Takahashi H, Takigawa I, Watanabe M, Anwar D, Shibata M, Tomomori-Sato C, Sato S, Ranjan A, Seidel CW, Tsukiyama T, Mizushima W, Hayashi M, Ohkawa Y, Conaway JW, Conaway RC, Hatakeyama S
Nature communications65941(2015 Jan)

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.
Krebs AR, Demmers J, Karmodiya K, Chang NC, Chang AC, Tora L
EMBO reports11(7)541-7(2010 Jul)

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

The chromatin-targeting protein Brd2 is required for neural tube closure and embryogenesis.
Gyuris A, Donovan DJ, Seymour KA, Lovasco LA, Smilowitz NR, Halperin AL, Klysik JE, Freiman RN
Biochimica et biophysica acta1789(5)413-21(2009 May)

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Med26 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Med26 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu04278	NM_027485.4 Latest version!	Mus musculus mediator complex subunit 26 (Med26), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$349.30 $499.00
OMu41056	XM_006509739.4 Latest version!	Mus musculus mediator complex subunit 26 (Med26), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OMu41056	XM_006509739.3	Mus musculus mediator complex subunit 26 (Med26), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Med26 ( XM_006509739.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006509802.1 Mus musculus mediator complex subunit 26 (Med26), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu41056
Clone ID Related Accession (Same CDS sequence)	XM_006509739.4 , XM_006509739.3
Accession Version	XM_006509739.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	mediator of RNA polymerase II transcription subunit 26 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006509739.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGCAG TGTTGGAAGT GATCTCCAGT CTGGAGAGAT ACCCCATCAC CAAAGAGGCA 
CTGGAGGAGA CACGACTAGG GAAGCTCATC AATGATGTCC GCAAGAAAAC CAAGAATGAG 
GAGCTGGCCA AGCGGGCCAA GAGGCTGCTA CGAAGCTGGC AGAAGCTCAT CGAGCCTGTA 
CACCAGAACG AAGTGGCACT ACGGGCACTG GCAGGAGCTG CAGGCTCTGC CAATGGGGGT 
GCGCACAACT GCCGACCAGA GATGGGAGTG GCTGGTGCAC CCAAGAGCAT CCATGACCTG 
AAGAATCGCA ACGACATCCA AAGGCTCCCT GGGCAACGGC TAGATAGGCT GGGCAGCCGT 
AAGCGCAGGG GGGACCAGCG TGACCTGGGC CACCCAGGGC CACCCCACAA AGTTTCCAAA 
GGCAGTCCTG ACCCTCTGGT TCCCAATGCA TCCCCTCTCC CCACCAATGG GATCAGCGGG 
AGCCCAGAGA GCTTACCCAG CCCCCTGGAT GGCAGTGGGC ACTTGGGCCC TGATGGCAGC 
CGCCTGGAGC CCAGTGATAA TGAGAAGCAC AGCACCAAGA TTCCCGTGAA CGCCGTGCGG 
CCGCGCCCCA GCTCTCCCGG CTTGGGCAAA CCCCCAGTTC CCTGCCTGCA GACCAAGGCT 
GCACAGTTGC AGCAGTTGGA CAGGGCAGAT GAGTCCCCAG GCCCTCCCTA TCCCAGGGGG 
TCCTCTCGCT GCTCCTTCAG CCCCCGGAAC TCACGGCACG AAGGCTCCTT TTCACGGCAT 
CGGAGCTCTT ACATACCCAA GGGCCAGGTG TCCAGCCCTT CCCCATGGCC CCAGCCACCG 
GACAACACGC AGGTACCATC CCCACTCCCG CTGGCCCAGC CACCCACGCC CCCTGTGCGC 
CGTCAGGAGC TGCTGCCTAA TGCTGAGAGC CCTGTGCACT GGCCAGAGCA GTCTGAGGGC 
CACCCACGGC TAACGGGGCC AGCCTGCAGG GCTGGATTTT CTCCAGATTC CTCCAAGGCG 
GACAGTGATG CTACCTCTTC GGGTGGCTCG GACAGCAAAA AGAAAAAGAG GTACCGACCT 
CGAGACTACA CAGTGAACTT GGACGGGCAG GTGGCTGAGG CTGGTGTTAA ACCTGTGCGG 
TTAAAAGAGC GGAAGCTCAC CTTTGACCCC ATGACAAGAC AGATCAGGCC TCTGACCCAG 
AAAGAGCCGG TGCGGGCTGA CAGCCCAGTA CCCACAGAGC AGCTGCCTAG GACAGAGCTG 
GAGCAGCAGG AGGTCAAGGC CAGCCTCCAG AGCCCTTTTG AGCAGACGAA CTGGAAGGAG 
CTATCACGAA ATGAGATCAT ACAGTCCTAC CTGAGCCGCC AGAGCAGCTT GCTATCCTCC 
TCAGGCGCAC AGACCCCAGG TGCGCACCAC TTTATGGCTG AATACCTGAA GCAGGAGGAG 
AGCAGTCGGC AAGGGGCCCG GCAGCCCCAT GTGCTGCTAC CACTGCCCAC ACCCACTGAC 
CTACCAGGGC TCACACGTGA GGTCACGCAG GATGATCTGG ACAGAATCCA GGCCCAGCAA 
TGGCCAGGGG TTAACGGGTG TGAAGACACA CAGGGTAATT GGTATGACTG GACACAGTGT 
ATATCGCTCG ACCCTCATGG TGACGATGGG CGCTTGAACA TTCTGCCTTA TGTCTGCTTG 
GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006509802.1
CDS	237..1922
Translation	MVAVLEVISSLERYPITKEALEETRLGKLINDVRKKTKNEELAKRAKRLLRSWQKLIEPVHQNEVALRALAGAAGSANGGAHNCRPEMGVAGAPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPHKVSKGSPDPLVPNASPLPTNGISGSPESLPSPLDGSGHLGPDGSRLEPSDNEKHSTKIPVNAVRPRPSSPGLGKPPVPCLQTKAAQLQQLDRADESPGPPYPRGSSRCSFSPRNSRHEGSFSRHRSSYIPKGQVSSPSPWPQPPDNTQVPSPLPLAQPPTPPVRRQELLPNAESPVHWPEQSEGHPRLTGPACRAGFSPDSSKADSDATSSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIRPLTQKEPVRADSPVPTEQLPRTELEQQEVKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMAEYLKQEESSRQGARQPHVLLPLPTPTDLPGLTREVTQDDLDRIQAQQWPGVNGCEDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD

Target ORF information:

RefSeq Version	XM_006509739.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus mediator complex subunit 26 (Med26), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006509739.3

ORF Insert Sequence:

ATGGTGGCAG TGTTGGAAGT GATCTCCAGT CTGGAGAGAT ACCCCATCAC CAAAGAGGCA 
CTGGAGGAGA CACGACTAGG GAAGCTCATC AATGATGTCC GCAAGAAAAC CAAGAATGAG 
GAGCTGGCCA AGCGGGCCAA GAGGCTGCTA CGAAGCTGGC AGAAGCTCAT CGAGCCTGTA 
CACCAGAACG AAGTGGCACT ACGGGCACTG GCAGGAGCTG CAGGCTCTGC CAATGGGGGT 
GCGCACAACT GCCGACCAGA GATGGGAGTG GCTGGTGCAC CCAAGAGCAT CCATGACCTG 
AAGAATCGCA ACGACATCCA AAGGCTCCCT GGGCAACGGC TAGATAGGCT GGGCAGCCGT 
AAGCGCAGGG GGGACCAGCG TGACCTGGGC CACCCAGGGC CACCCCACAA AGTTTCCAAA 
GGCAGTCCTG ACCCTCTGGT TCCCAATGCA TCCCCTCTCC CCACCAATGG GATCAGCGGG 
AGCCCAGAGA GCTTACCCAG CCCCCTGGAT GGCAGTGGGC ACTTGGGCCC TGATGGCAGC 
CGCCTGGAGC CCAGTGATAA TGAGAAGCAC AGCACCAAGA TTCCCGTGAA CGCCGTGCGG 
CCGCGCCCCA GCTCTCCCGG CTTGGGCAAA CCCCCAGTTC CCTGCCTGCA GACCAAGGCT 
GCACAGTTGC AGCAGTTGGA CAGGGCAGAT GAGTCCCCAG GCCCTCCCTA TCCCAGGGGG 
TCCTCTCGCT GCTCCTTCAG CCCCCGGAAC TCACGGCACG AAGGCTCCTT TTCACGGCAT 
CGGAGCTCTT ACATACCCAA GGGCCAGGTG TCCAGCCCTT CCCCATGGCC CCAGCCACCG 
GACAACACGC AGGTACCATC CCCACTCCCG CTGGCCCAGC CACCCACGCC CCCTGTGCGC 
CGTCAGGAGC TGCTGCCTAA TGCTGAGAGC CCTGTGCACT GGCCAGAGCA GTCTGAGGGC 
CACCCACGGC TAACGGGGCC AGCCTGCAGG GCTGGATTTT CTCCAGATTC CTCCAAGGCG 
GACAGTGATG CTACCTCTTC GGGTGGCTCG GACAGCAAAA AGAAAAAGAG GTACCGACCT 
CGAGACTACA CAGTGAACTT GGACGGGCAG GTGGCTGAGG CTGGTGTTAA ACCTGTGCGG 
TTAAAAGAGC GGAAGCTCAC CTTTGACCCC ATGACAAGAC AGATCAGGCC TCTGACCCAG 
AAAGAGCCGG TGCGGGCTGA CAGCCCAGTA CCCACAGAGC AGCTGCCTAG GACAGAGCTG 
GAGCAGCAGG AGGTCAAGGC CAGCCTCCAG AGCCCTTTTG AGCAGACGAA CTGGAAGGAG 
CTATCACGAA ATGAGATCAT ACAGTCCTAC CTGAGCCGCC AGAGCAGCTT GCTATCCTCC 
TCAGGCGCAC AGACCCCAGG TGCGCACCAC TTTATGGCTG AATACCTGAA GCAGGAGGAG 
AGCAGTCGGC AAGGGGCCCG GCAGCCCCAT GTGCTGCTAC CACTGCCCAC ACCCACTGAC 
CTACCAGGGC TCACACGTGA GGTCACGCAG GATGATCTGG ACAGAATCCA GGCCCAGCAA 
TGGCCAGGGG TTAACGGGTG TGAAGACACA CAGGGTAATT GGTATGACTG GACACAGTGT 
ATATCGCTCG ACCCTCATGG TGACGATGGG CGCTTGAACA TTCTGCCTTA TGTCTGCTTG 
GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Med26 ( NM_027485.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_081761.2 Mus musculus mediator complex subunit 26 (Med26), mRNA.

Price & Availability↑

CloneID	OMu04278
Clone ID Related Accession (Same CDS sequence)	NM_027485.4
Accession Version	NM_027485.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1767bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Mus musculus(house mouse)
Product	mediator of RNA polymerase II transcription subunit 26
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY059601.1 and BC054737.1. On Nov 19, 2009 this sequence version replaced NM_027485.3. ##Evidence-Data-START## Transcript exon combination :: BC054737.1, AK083035.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164140 [ECO:0000348] ##Evidence-Data-END##

ATGACAGCGG CTCCGGCGTC TCCGCAGCAG ATGAGGGACC GGCTGCTACA GGCCATCGAC 
TCCCAGAGCA ACATCCGGAA CATGGTGGCA GTGTTGGAAG TGATCTCCAG TCTGGAGAGA 
TACCCCATCA CCAAAGAGGC ACTGGAGGAG ACACGACTAG GGAAGCTCAT CAATGATGTC 
CGCAAGAAAA CCAAGAATGA GGAGCTGGCC AAGCGGGCCA AGAGGCTGCT ACGAAGCTGG 
CAGAAGCTCA TCGAGCCTGT ACACCAGAAC GAAGTGGCAC TACGGGCACT GGCAGGAGCT 
GCAGGCTCTG CCAATGGGGG TGCGCACAAC TGCCGACCAG AGATGGGAGT GGCTGGTGCA 
CCCAAGAGCA TCCATGACCT GAAGAATCGC AACGACATCC AAAGGCTCCC TGGGCAACGG 
CTAGATAGGC TGGGCAGCCG TAAGCGCAGG GGGGACCAGC GTGACCTGGG CCACCCAGGG 
CCACCCCACA AAGTTTCCAA AGGCAGTCCT GACCCTCTGG TTCCCAATGC ATCCCCTCTC 
CCCACCAATG GGATCAGCGG GAGCCCAGAG AGCTTACCCA GCCCCCTGGA TGGCAGTGGG 
CACTTGGGCC CTGATGGCAG CCGCCTGGAG CCCAGTGATA ATGAGAAGCA CAGCACCAAG 
ATTCCCGTGA ACGCCGTGCG GCCGCGCCCC AGCTCTCCCG GCTTGGGCAA ACCCCCAGTT 
CCCTGCCTGC AGACCAAGGC TGCACAGTTG CAGCAGTTGG ACAGGGCAGA TGAGTCCCCA 
GGCCCTCCCT ATCCCAGGGG GTCCTCTCGC TGCTCCTTCA GCCCCCGGAA CTCACGGCAC 
GAAGGCTCCT TTTCACGGCA TCGGAGCTCT TACATACCCA AGGGCCAGGT GTCCAGCCCT 
TCCCCATGGC CCCAGCCACC GGACAACACG CAGGTACCAT CCCCACTCCC GCTGGCCCAG 
CCACCCACGC CCCCTGTGCG CCGTCAGGAG CTGCTGCCTA ATGCTGAGAG CCCTGTGCAC 
TGGCCAGAGC AGTCTGAGGG CCACCCACGG CTAACGGGGC CAGCCTGCAG GGCTGGATTT 
TCTCCAGATT CCTCCAAGGC GGACAGTGAT GCTACCTCTT CGGGTGGCTC GGACAGCAAA 
AAGAAAAAGA GGTACCGACC TCGAGACTAC ACAGTGAACT TGGACGGGCA GGTGGCTGAG 
GCTGGTGTTA AACCTGTGCG GTTAAAAGAG CGGAAGCTCA CCTTTGACCC CATGACAAGA 
CAGATCAGGC CTCTGACCCA GAAAGAGCCG GTGCGGGCTG ACAGCCCAGT ACCCACAGAG 
CAGCTGCCTA GGACAGAGCT GGAGCAGCAG GAGGTCAAGG CCAGCCTCCA GAGCCCTTTT 
GAGCAGACGA ACTGGAAGGA GCTATCACGA AATGAGATCA TACAGTCCTA CCTGAGCCGC 
CAGAGCAGCT TGCTATCCTC CTCAGGCGCA CAGACCCCAG GTGCGCACCA CTTTATGGCT 
GAATACCTGA AGCAGGAGGA GAGCAGTCGG CAAGGGGCCC GGCAGCCCCA TGTGCTGCTA 
CCACTGCCCA CACCCACTGA CCTACCAGGG CTCACACGTG AGGTCACGCA GGATGATCTG 
GACAGAATCC AGGCCCAGCA ATGGCCAGGG GTTAACGGGT GTGAAGACAC ACAGGGTAAT 
TGGTATGACT GGACACAGTG TATATCGCTC GACCCTCATG GTGACGATGG GCGCTTGAAC 
ATTCTGCCTT ATGTCTGCTT GGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_081761.2
CDS	345..2111
Translation	MTAAPASPQQMRDRLLQAIDSQSNIRNMVAVLEVISSLERYPITKEALEETRLGKLINDVRKKTKNEELAKRAKRLLRSWQKLIEPVHQNEVALRALAGAAGSANGGAHNCRPEMGVAGAPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPHKVSKGSPDPLVPNASPLPTNGISGSPESLPSPLDGSGHLGPDGSRLEPSDNEKHSTKIPVNAVRPRPSSPGLGKPPVPCLQTKAAQLQQLDRADESPGPPYPRGSSRCSFSPRNSRHEGSFSRHRSSYIPKGQVSSPSPWPQPPDNTQVPSPLPLAQPPTPPVRRQELLPNAESPVHWPEQSEGHPRLTGPACRAGFSPDSSKADSDATSSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIRPLTQKEPVRADSPVPTEQLPRTELEQQEVKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMAEYLKQEESSRQGARQPHVLLPLPTPTDLPGLTREVTQDDLDRIQAQQWPGVNGCEDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD

Target ORF information:

RefSeq Version	NM_027485.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus mediator complex subunit 26 (Med26), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_027485.4

ORF Insert Sequence:

ATGACAGCGG CTCCGGCGTC TCCGCAGCAG ATGAGGGACC GGCTGCTACA GGCCATCGAC 
TCCCAGAGCA ACATCCGGAA CATGGTGGCA GTGTTGGAAG TGATCTCCAG TCTGGAGAGA 
TACCCCATCA CCAAAGAGGC ACTGGAGGAG ACACGACTAG GGAAGCTCAT CAATGATGTC 
CGCAAGAAAA CCAAGAATGA GGAGCTGGCC AAGCGGGCCA AGAGGCTGCT ACGAAGCTGG 
CAGAAGCTCA TCGAGCCTGT ACACCAGAAC GAAGTGGCAC TACGGGCACT GGCAGGAGCT 
GCAGGCTCTG CCAATGGGGG TGCGCACAAC TGCCGACCAG AGATGGGAGT GGCTGGTGCA 
CCCAAGAGCA TCCATGACCT GAAGAATCGC AACGACATCC AAAGGCTCCC TGGGCAACGG 
CTAGATAGGC TGGGCAGCCG TAAGCGCAGG GGGGACCAGC GTGACCTGGG CCACCCAGGG 
CCACCCCACA AAGTTTCCAA AGGCAGTCCT GACCCTCTGG TTCCCAATGC ATCCCCTCTC 
CCCACCAATG GGATCAGCGG GAGCCCAGAG AGCTTACCCA GCCCCCTGGA TGGCAGTGGG 
CACTTGGGCC CTGATGGCAG CCGCCTGGAG CCCAGTGATA ATGAGAAGCA CAGCACCAAG 
ATTCCCGTGA ACGCCGTGCG GCCGCGCCCC AGCTCTCCCG GCTTGGGCAA ACCCCCAGTT 
CCCTGCCTGC AGACCAAGGC TGCACAGTTG CAGCAGTTGG ACAGGGCAGA TGAGTCCCCA 
GGCCCTCCCT ATCCCAGGGG GTCCTCTCGC TGCTCCTTCA GCCCCCGGAA CTCACGGCAC 
GAAGGCTCCT TTTCACGGCA TCGGAGCTCT TACATACCCA AGGGCCAGGT GTCCAGCCCT 
TCCCCATGGC CCCAGCCACC GGACAACACG CAGGTACCAT CCCCACTCCC GCTGGCCCAG 
CCACCCACGC CCCCTGTGCG CCGTCAGGAG CTGCTGCCTA ATGCTGAGAG CCCTGTGCAC 
TGGCCAGAGC AGTCTGAGGG CCACCCACGG CTAACGGGGC CAGCCTGCAG GGCTGGATTT 
TCTCCAGATT CCTCCAAGGC GGACAGTGAT GCTACCTCTT CGGGTGGCTC GGACAGCAAA 
AAGAAAAAGA GGTACCGACC TCGAGACTAC ACAGTGAACT TGGACGGGCA GGTGGCTGAG 
GCTGGTGTTA AACCTGTGCG GTTAAAAGAG CGGAAGCTCA CCTTTGACCC CATGACAAGA 
CAGATCAGGC CTCTGACCCA GAAAGAGCCG GTGCGGGCTG ACAGCCCAGT ACCCACAGAG 
CAGCTGCCTA GGACAGAGCT GGAGCAGCAG GAGGTCAAGG CCAGCCTCCA GAGCCCTTTT 
GAGCAGACGA ACTGGAAGGA GCTATCACGA AATGAGATCA TACAGTCCTA CCTGAGCCGC 
CAGAGCAGCT TGCTATCCTC CTCAGGCGCA CAGACCCCAG GTGCGCACCA CTTTATGGCT 
GAATACCTGA AGCAGGAGGA GAGCAGTCGG CAAGGGGCCC GGCAGCCCCA TGTGCTGCTA 
CCACTGCCCA CACCCACTGA CCTACCAGGG CTCACACGTG AGGTCACGCA GGATGATCTG 
GACAGAATCC AGGCCCAGCA ATGGCCAGGG GTTAACGGGT GTGAAGACAC ACAGGGTAAT 
TGGTATGACT GGACACAGTG TATATCGCTC GACCCTCATG GTGACGATGG GCGCTTGAAC 
ATTCTGCCTT ATGTCTGCTT GGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Med26 ( XM_006509739.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006509802.1 Mus musculus mediator complex subunit 26 (Med26), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu41056
Clone ID Related Accession (Same CDS sequence)	XM_006509739.4 , XM_006509739.3
Accession Version	XM_006509739.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1686bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	mediator of RNA polymerase II transcription subunit 26 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000074.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006509739.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGCAG TGTTGGAAGT GATCTCCAGT CTGGAGAGAT ACCCCATCAC CAAAGAGGCA 
CTGGAGGAGA CACGACTAGG GAAGCTCATC AATGATGTCC GCAAGAAAAC CAAGAATGAG 
GAGCTGGCCA AGCGGGCCAA GAGGCTGCTA CGAAGCTGGC AGAAGCTCAT CGAGCCTGTA 
CACCAGAACG AAGTGGCACT ACGGGCACTG GCAGGAGCTG CAGGCTCTGC CAATGGGGGT 
GCGCACAACT GCCGACCAGA GATGGGAGTG GCTGGTGCAC CCAAGAGCAT CCATGACCTG 
AAGAATCGCA ACGACATCCA AAGGCTCCCT GGGCAACGGC TAGATAGGCT GGGCAGCCGT 
AAGCGCAGGG GGGACCAGCG TGACCTGGGC CACCCAGGGC CACCCCACAA AGTTTCCAAA 
GGCAGTCCTG ACCCTCTGGT TCCCAATGCA TCCCCTCTCC CCACCAATGG GATCAGCGGG 
AGCCCAGAGA GCTTACCCAG CCCCCTGGAT GGCAGTGGGC ACTTGGGCCC TGATGGCAGC 
CGCCTGGAGC CCAGTGATAA TGAGAAGCAC AGCACCAAGA TTCCCGTGAA CGCCGTGCGG 
CCGCGCCCCA GCTCTCCCGG CTTGGGCAAA CCCCCAGTTC CCTGCCTGCA GACCAAGGCT 
GCACAGTTGC AGCAGTTGGA CAGGGCAGAT GAGTCCCCAG GCCCTCCCTA TCCCAGGGGG 
TCCTCTCGCT GCTCCTTCAG CCCCCGGAAC TCACGGCACG AAGGCTCCTT TTCACGGCAT 
CGGAGCTCTT ACATACCCAA GGGCCAGGTG TCCAGCCCTT CCCCATGGCC CCAGCCACCG 
GACAACACGC AGGTACCATC CCCACTCCCG CTGGCCCAGC CACCCACGCC CCCTGTGCGC 
CGTCAGGAGC TGCTGCCTAA TGCTGAGAGC CCTGTGCACT GGCCAGAGCA GTCTGAGGGC 
CACCCACGGC TAACGGGGCC AGCCTGCAGG GCTGGATTTT CTCCAGATTC CTCCAAGGCG 
GACAGTGATG CTACCTCTTC GGGTGGCTCG GACAGCAAAA AGAAAAAGAG GTACCGACCT 
CGAGACTACA CAGTGAACTT GGACGGGCAG GTGGCTGAGG CTGGTGTTAA ACCTGTGCGG 
TTAAAAGAGC GGAAGCTCAC CTTTGACCCC ATGACAAGAC AGATCAGGCC TCTGACCCAG 
AAAGAGCCGG TGCGGGCTGA CAGCCCAGTA CCCACAGAGC AGCTGCCTAG GACAGAGCTG 
GAGCAGCAGG AGGTCAAGGC CAGCCTCCAG AGCCCTTTTG AGCAGACGAA CTGGAAGGAG 
CTATCACGAA ATGAGATCAT ACAGTCCTAC CTGAGCCGCC AGAGCAGCTT GCTATCCTCC 
TCAGGCGCAC AGACCCCAGG TGCGCACCAC TTTATGGCTG AATACCTGAA GCAGGAGGAG 
AGCAGTCGGC AAGGGGCCCG GCAGCCCCAT GTGCTGCTAC CACTGCCCAC ACCCACTGAC 
CTACCAGGGC TCACACGTGA GGTCACGCAG GATGATCTGG ACAGAATCCA GGCCCAGCAA 
TGGCCAGGGG TTAACGGGTG TGAAGACACA CAGGGTAATT GGTATGACTG GACACAGTGT 
ATATCGCTCG ACCCTCATGG TGACGATGGG CGCTTGAACA TTCTGCCTTA TGTCTGCTTG 
GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006509802.1
CDS	202..1887
Translation	MVAVLEVISSLERYPITKEALEETRLGKLINDVRKKTKNEELAKRAKRLLRSWQKLIEPVHQNEVALRALAGAAGSANGGAHNCRPEMGVAGAPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPHKVSKGSPDPLVPNASPLPTNGISGSPESLPSPLDGSGHLGPDGSRLEPSDNEKHSTKIPVNAVRPRPSSPGLGKPPVPCLQTKAAQLQQLDRADESPGPPYPRGSSRCSFSPRNSRHEGSFSRHRSSYIPKGQVSSPSPWPQPPDNTQVPSPLPLAQPPTPPVRRQELLPNAESPVHWPEQSEGHPRLTGPACRAGFSPDSSKADSDATSSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIRPLTQKEPVRADSPVPTEQLPRTELEQQEVKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMAEYLKQEESSRQGARQPHVLLPLPTPTDLPGLTREVTQDDLDRIQAQQWPGVNGCEDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD

Target ORF information:

RefSeq Version	XM_006509739.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus mediator complex subunit 26 (Med26), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006509739.4

ORF Insert Sequence:

ATGGTGGCAG TGTTGGAAGT GATCTCCAGT CTGGAGAGAT ACCCCATCAC CAAAGAGGCA 
CTGGAGGAGA CACGACTAGG GAAGCTCATC AATGATGTCC GCAAGAAAAC CAAGAATGAG 
GAGCTGGCCA AGCGGGCCAA GAGGCTGCTA CGAAGCTGGC AGAAGCTCAT CGAGCCTGTA 
CACCAGAACG AAGTGGCACT ACGGGCACTG GCAGGAGCTG CAGGCTCTGC CAATGGGGGT 
GCGCACAACT GCCGACCAGA GATGGGAGTG GCTGGTGCAC CCAAGAGCAT CCATGACCTG 
AAGAATCGCA ACGACATCCA AAGGCTCCCT GGGCAACGGC TAGATAGGCT GGGCAGCCGT 
AAGCGCAGGG GGGACCAGCG TGACCTGGGC CACCCAGGGC CACCCCACAA AGTTTCCAAA 
GGCAGTCCTG ACCCTCTGGT TCCCAATGCA TCCCCTCTCC CCACCAATGG GATCAGCGGG 
AGCCCAGAGA GCTTACCCAG CCCCCTGGAT GGCAGTGGGC ACTTGGGCCC TGATGGCAGC 
CGCCTGGAGC CCAGTGATAA TGAGAAGCAC AGCACCAAGA TTCCCGTGAA CGCCGTGCGG 
CCGCGCCCCA GCTCTCCCGG CTTGGGCAAA CCCCCAGTTC CCTGCCTGCA GACCAAGGCT 
GCACAGTTGC AGCAGTTGGA CAGGGCAGAT GAGTCCCCAG GCCCTCCCTA TCCCAGGGGG 
TCCTCTCGCT GCTCCTTCAG CCCCCGGAAC TCACGGCACG AAGGCTCCTT TTCACGGCAT 
CGGAGCTCTT ACATACCCAA GGGCCAGGTG TCCAGCCCTT CCCCATGGCC CCAGCCACCG 
GACAACACGC AGGTACCATC CCCACTCCCG CTGGCCCAGC CACCCACGCC CCCTGTGCGC 
CGTCAGGAGC TGCTGCCTAA TGCTGAGAGC CCTGTGCACT GGCCAGAGCA GTCTGAGGGC 
CACCCACGGC TAACGGGGCC AGCCTGCAGG GCTGGATTTT CTCCAGATTC CTCCAAGGCG 
GACAGTGATG CTACCTCTTC GGGTGGCTCG GACAGCAAAA AGAAAAAGAG GTACCGACCT 
CGAGACTACA CAGTGAACTT GGACGGGCAG GTGGCTGAGG CTGGTGTTAA ACCTGTGCGG 
TTAAAAGAGC GGAAGCTCAC CTTTGACCCC ATGACAAGAC AGATCAGGCC TCTGACCCAG 
AAAGAGCCGG TGCGGGCTGA CAGCCCAGTA CCCACAGAGC AGCTGCCTAG GACAGAGCTG 
GAGCAGCAGG AGGTCAAGGC CAGCCTCCAG AGCCCTTTTG AGCAGACGAA CTGGAAGGAG 
CTATCACGAA ATGAGATCAT ACAGTCCTAC CTGAGCCGCC AGAGCAGCTT GCTATCCTCC 
TCAGGCGCAC AGACCCCAGG TGCGCACCAC TTTATGGCTG AATACCTGAA GCAGGAGGAG 
AGCAGTCGGC AAGGGGCCCG GCAGCCCCAT GTGCTGCTAC CACTGCCCAC ACCCACTGAC 
CTACCAGGGC TCACACGTGA GGTCACGCAG GATGATCTGG ACAGAATCCA GGCCCAGCAA 
TGGCCAGGGG TTAACGGGTG TGAAGACACA CAGGGTAATT GGTATGACTG GACACAGTGT 
ATATCGCTCG ACCCTCATGG TGACGATGGG CGCTTGAACA TTCTGCCTTA TGTCTGCTTG 
GACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex.
Nature communications65941(2015 Jan)
Takahashi H,Takigawa I,Watanabe M,Anwar D,Shibata M,Tomomori-Sato C,Sato S,Ranjan A,Seidel CW,Tsukiyama T,Mizushima W,Hayashi M,Ohkawa Y,Conaway JW,Conaway RC,Hatakeyama S

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.
EMBO reports11(7)541-7(2010 Jul)
Krebs AR,Demmers J,Karmodiya K,Chang NC,Chang AC,Tora L

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H

The chromatin-targeting protein Brd2 is required for neural tube closure and embryogenesis.
Biochimica et biophysica acta1789(5)413-21(2009 May)
Gyuris A,Donovan DJ,Seymour KA,Lovasco LA,Smilowitz NR,Halperin AL,Klysik JE,Freiman RN

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Nucleic acids research31(1)278-81(2003 Jan)
Stryke D,Kawamoto M,Huang CC,Johns SJ,King LA,Harper CA,Meng EC,Lee RE,Yee A,L'Italien L,Chuang PT,Young SG,Skarnes WC,Babbitt PC,Ferrin TE

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Med26 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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