Tifab cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tifab
Entrez Gene ID	212937
Full Name	TRAF-interacting protein with forkhead-associated domain, family member B
General protein information	Preferred Names TRAF-interacting protein with forkhead-associated domain, family member B Names TRAF-interacting protein with FHA domain-containing protein B TIFA like protein TIFA related protein TIFAB tifab
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 B1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006517204.3	XP_006517267.1	TRAF-interacting protein with FHA domain-containing protein B isoform X1
XM_006517205.2	XP_006517268.1	TRAF-interacting protein with FHA domain-containing protein B isoform X1
XM_006517205.4	XP_006517268.1	TRAF-interacting protein with FHA domain-containing protein B isoform X1
XM_006517205.3	XP_006517268.1	TRAF-interacting protein with FHA domain-containing protein B isoform X1
NM_001168615.1	NP_001162086.1	TRAF-interacting protein with FHA domain-containing protein B
NM_145976.4	NP_666088.1	TRAF-interacting protein with FHA domain-containing protein B
XM_006517204.2	XP_006517267.1	TRAF-interacting protein with FHA domain-containing protein B isoform X1
XM_006517204.4	XP_006517267.1	TRAF-interacting protein with FHA domain-containing protein B isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Tifab	NP_666088.1
Rattus norvegicus (Norway rat)	Tifab	NP_001020200.1
Homo sapiens (human)	TIFAB	NP_001092691.1
Canis lupus familiaris (dog)	TIFAB	XP_005626616.1
Bos taurus (cattle)	TIFAB	XP_002689248.2
Pan troglodytes (chimpanzee)	TIFAB	XP_527016.3
	LOC715045	XP_001105096.2

Gene Ontology
Bibliography

Related articles in PubMed

Epistasis between TIFAB and miR-146a: neighboring genes in del(5q) myelodysplastic syndrome.
Varney ME, Choi K, Bolanos L, Christie S, Fang J, Grimes LH, Maciejewski JP, Inoue JI, Starczynowski DT
Leukemia31(2)491-495(2017 02)

Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms.
Stoddart A, Qian Z, Fernald AA, Bergerson RJ, Wang J, Karrison T, Anastasi J, Bartom ET, Sarver AL, McNerney ME, Largaespada DA, Le Beau MM
Haematologica101(6)e232-6(2016 06)

Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signaling.
Varney ME, Niederkorn M, Konno H, Matsumura T, Gohda J, Yoshida N, Akiyama T, Christie S, Fang J, Miller D, Jerez A, Karsan A, Maciejewski JP, Meetei RA, Inoue J, Starczynowski DT
The Journal of experimental medicine212(11)1967-85(2015 Oct)

TRAF-interacting protein with a forkhead-associated domain B (TIFAB) is a negative regulator of the TRAF6-induced cellular functions.
Matsumura T, Kawamura-Tsuzuku J, Yamamoto T, Semba K, Inoue J
Journal of biochemistry146(3)375-81(2009 Sep)

TIFAB inhibits TIFA, TRAF-interacting protein with a forkhead-associated domain.
Matsumura T, Semba K, Azuma S, Ikawa S, Gohda J, Akiyama T, Inoue J
Biochemical and biophysical research communications317(1)230-4(2004 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TIFAB loss increases TRAF6 protein and the dynamic range of TLR4 signaling
Title: Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signaling.

study shows TIFAB is mainly expressed in B cells rather than T cells in the spleen; results suggest TIFAB could act as a negative regulator of TRAF6-induced cellular function such as B cell proliferation and maturation of dendritic cellss & macrophages
Title: TRAF-interacting protein with a forkhead-associated domain B (TIFAB) is a negative regulator of the TRAF6-induced cellular functions.

The following Tifab gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tifab cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu11551	NM_145976.4 Latest version!	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu11551	NM_001168615.1 Latest version!	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu11551	XM_006517205.4 Latest version!	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OMu11551	XM_006517204.4 Latest version!	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu11551	XM_006517205.2	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu11551	XM_006517205.3	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu11551	XM_006517204.2	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu11551	XM_006517204.3	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tifab ( NM_001168615.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001162086.1 Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu11551
Clone ID Related Accession (Same CDS sequence)	XM_006517204.3 , XM_006517205.2 , XM_006517205.4 , XM_006517205.3 , NM_001168615.1 , NM_145976.4 , XM_006517204.2 , XM_006517204.4
Accession Version	NM_001168615.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Mus musculus(house mouse)
Product	TRAF-interacting protein with FHA domain-containing protein B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY209244.1, AK153654.1 and AC124395.5. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC031130.1, AK153654.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001162086.1
CDS	573..1016
Translation	MERPLTVLQVSLYHPTQGPVAFAHVPQQLQHDASRLLVGRGQNTHLQLQLPQLSRYHLSLEPYLEKGSSLLAFCLKVLTRKSCVWVNGLPLRYLEQVPLGTINRISFSGIQMLVRKEGGASLETFVCYFHLSPSPLIYRPKAQETDE

Target ORF information:

RefSeq Version	NM_001168615.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001168615.1

ORF Insert Sequence:

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tifab ( NM_145976.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_666088.1 Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu11551
Clone ID Related Accession (Same CDS sequence)	XM_006517204.3 , XM_006517205.2 , XM_006517205.4 , XM_006517205.3 , NM_001168615.1 , NM_145976.4 , XM_006517204.2 , XM_006517204.4
Accession Version	NM_145976.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Mus musculus(house mouse)
Product	TRAF-interacting protein with FHA domain-containing protein B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY209244.1, AK036643.1 and AC124395.5. On Dec 16, 2009 this sequence version replaced NM_145976.3. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK036643.1, BC005528.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_666088.1
CDS	509..952
Translation	MERPLTVLQVSLYHPTQGPVAFAHVPQQLQHDASRLLVGRGQNTHLQLQLPQLSRYHLSLEPYLEKGSSLLAFCLKVLTRKSCVWVNGLPLRYLEQVPLGTINRISFSGIQMLVRKEGGASLETFVCYFHLSPSPLIYRPKAQETDE

Target ORF information:

RefSeq Version	NM_145976.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145976.4

ORF Insert Sequence:

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tifab ( XM_006517204.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517267.1 Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu11551
Clone ID Related Accession (Same CDS sequence)	XM_006517204.3 , XM_006517205.2 , XM_006517205.4 , XM_006517205.3 , NM_001168615.1 , NM_145976.4 , XM_006517204.2 , XM_006517204.4
Accession Version	XM_006517204.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	TRAF-interacting protein with FHA domain-containing protein B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006517204.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517267.1
CDS	696..1139
Translation	MERPLTVLQVSLYHPTQGPVAFAHVPQQLQHDASRLLVGRGQNTHLQLQLPQLSRYHLSLEPYLEKGSSLLAFCLKVLTRKSCVWVNGLPLRYLEQVPLGTINRISFSGIQMLVRKEGGASLETFVCYFHLSPSPLIYRPKAQETDE

Target ORF information:

RefSeq Version	XM_006517204.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517204.3

ORF Insert Sequence:

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tifab ( XM_006517205.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517268.1 Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu11551
Clone ID Related Accession (Same CDS sequence)	XM_006517204.3 , XM_006517205.2 , XM_006517205.4 , XM_006517205.3 , NM_001168615.1 , NM_145976.4 , XM_006517204.2 , XM_006517204.4
Accession Version	XM_006517205.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	TRAF-interacting protein with FHA domain-containing protein B isoform X1
Comment

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517268.1
Translation	MERPLTVLQVSLYHPTQGPVAFAHVPQQLQHDASRLLVGRGQNTHLQLQLPQLSRYHLSLEPYLEKGSSLLAFCLKVLTRKSCVWVNGLPLRYLEQVPLGTINRISFSGIQMLVRKEGGASLETFVCYFHLSPSPLIYRPKAQETDE

Target ORF information:

RefSeq Version	XM_006517205.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517205.2

ORF Insert Sequence:

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tifab ( XM_006517205.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517268.1 Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu11551
Clone ID Related Accession (Same CDS sequence)	XM_006517204.3 , XM_006517205.2 , XM_006517205.4 , XM_006517205.3 , NM_001168615.1 , NM_145976.4 , XM_006517204.2 , XM_006517204.4
Accession Version	XM_006517205.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	TRAF-interacting protein with FHA domain-containing protein B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006517205.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517268.1
CDS	621..1064
Translation	MERPLTVLQVSLYHPTQGPVAFAHVPQQLQHDASRLLVGRGQNTHLQLQLPQLSRYHLSLEPYLEKGSSLLAFCLKVLTRKSCVWVNGLPLRYLEQVPLGTINRISFSGIQMLVRKEGGASLETFVCYFHLSPSPLIYRPKAQETDE

Target ORF information:

RefSeq Version	XM_006517205.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517205.4

ORF Insert Sequence:

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tifab ( XM_006517205.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517268.1 Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X2, mRNA.

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CloneID	OMu11551
Clone ID Related Accession (Same CDS sequence)	XM_006517204.3 , XM_006517205.2 , XM_006517205.4 , XM_006517205.3 , NM_001168615.1 , NM_145976.4 , XM_006517204.2 , XM_006517204.4
Accession Version	XM_006517205.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	TRAF-interacting protein with FHA domain-containing protein B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006517205.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517268.1
CDS	632..1075
Translation	MERPLTVLQVSLYHPTQGPVAFAHVPQQLQHDASRLLVGRGQNTHLQLQLPQLSRYHLSLEPYLEKGSSLLAFCLKVLTRKSCVWVNGLPLRYLEQVPLGTINRISFSGIQMLVRKEGGASLETFVCYFHLSPSPLIYRPKAQETDE

Target ORF information:

RefSeq Version	XM_006517205.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517205.3

ORF Insert Sequence:

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tifab ( XM_006517204.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517267.1 Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu11551
Clone ID Related Accession (Same CDS sequence)	XM_006517204.3 , XM_006517205.2 , XM_006517205.4 , XM_006517205.3 , NM_001168615.1 , NM_145976.4 , XM_006517204.2 , XM_006517204.4
Accession Version	XM_006517204.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-02-08
Organism	Mus musculus(House mouse)
Product	TRAF-interacting protein with FHA domain-containing protein B isoform X1
Comment

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517267.1
Translation	MERPLTVLQVSLYHPTQGPVAFAHVPQQLQHDASRLLVGRGQNTHLQLQLPQLSRYHLSLEPYLEKGSSLLAFCLKVLTRKSCVWVNGLPLRYLEQVPLGTINRISFSGIQMLVRKEGGASLETFVCYFHLSPSPLIYRPKAQETDE

Target ORF information:

RefSeq Version	XM_006517204.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517204.2

ORF Insert Sequence:

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tifab ( XM_006517204.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006517267.1 Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu11551
Clone ID Related Accession (Same CDS sequence)	XM_006517204.3 , XM_006517205.2 , XM_006517205.4 , XM_006517205.3 , NM_001168615.1 , NM_145976.4 , XM_006517204.2 , XM_006517204.4
Accession Version	XM_006517204.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	TRAF-interacting protein with FHA domain-containing protein B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006517204.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006517267.1
CDS	685..1128
Translation	MERPLTVLQVSLYHPTQGPVAFAHVPQQLQHDASRLLVGRGQNTHLQLQLPQLSRYHLSLEPYLEKGSSLLAFCLKVLTRKSCVWVNGLPLRYLEQVPLGTINRISFSGIQMLVRKEGGASLETFVCYFHLSPSPLIYRPKAQETDE

Target ORF information:

RefSeq Version	XM_006517204.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus TRAF-interacting protein with forkhead-associated domain, family member B (Tifab), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006517204.4

ORF Insert Sequence:

ATGGAGAGGC CCCTCACAGT CCTGCAGGTG AGCCTGTACC ACCCTACACA GGGCCCGGTC 
GCCTTTGCCC ACGTCCCACA GCAGCTGCAA CATGACGCCA GCCGGCTGTT GGTTGGGCGA 
GGACAGAACA CCCATCTCCA GCTGCAGCTG CCACAGTTGT CTCGCTACCA TTTGTCCCTG 
GAACCCTACC TGGAGAAAGG CAGCAGTCTG CTGGCCTTCT GCCTCAAGGT GCTGACCCGC 
AAGAGCTGTG TGTGGGTCAA CGGGCTGCCA CTGAGGTACC TGGAGCAGGT TCCCTTGGGC 
ACCATCAACA GAATCTCCTT CTCTGGCATC CAGATGCTAG TCCGCAAAGA GGGGGGAGCC 
TCCCTTGAGA CCTTTGTCTG CTACTTCCAT CTCAGCCCTT CACCCCTGAT TTACAGACCC 
AAGGCTCAGG AGACAGATGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Epistasis between TIFAB and miR-146a: neighboring genes in del(5q) myelodysplastic syndrome.
Leukemia31(2)491-495(2017 02)
Varney ME,Choi K,Bolanos L,Christie S,Fang J,Grimes LH,Maciejewski JP,Inoue JI,Starczynowski DT

Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms.
Haematologica101(6)e232-6(2016 06)
Stoddart A,Qian Z,Fernald AA,Bergerson RJ,Wang J,Karrison T,Anastasi J,Bartom ET,Sarver AL,McNerney ME,Largaespada DA,Le Beau MM

Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signaling.
The Journal of experimental medicine212(11)1967-85(2015 Oct)
Varney ME,Niederkorn M,Konno H,Matsumura T,Gohda J,Yoshida N,Akiyama T,Christie S,Fang J,Miller D,Jerez A,Karsan A,Maciejewski JP,Meetei RA,Inoue J,Starczynowski DT

TRAF-interacting protein with a forkhead-associated domain B (TIFAB) is a negative regulator of the TRAF6-induced cellular functions.
Journal of biochemistry146(3)375-81(2009 Sep)
Matsumura T,Kawamura-Tsuzuku J,Yamamoto T,Semba K,Inoue J

TIFAB inhibits TIFA, TRAF-interacting protein with a forkhead-associated domain.
Biochemical and biophysical research communications317(1)230-4(2004 Apr)
Matsumura T,Semba K,Azuma S,Ikawa S,Gohda J,Akiyama T,Inoue J

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Tifab cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

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ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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