Slc25a4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc25a4
Entrez Gene ID	11739
Full Name	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
Synonyms	AU019225,Ant1
General protein information	Preferred Names solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 Names ADP/ATP translocase 1 ADP,ATP carrier protein 1 ADP,ATP carrier protein, heart/skeletal muscle ANT 1 adenine nucleotide translocase-1 adenine nucleotide translocator 1, skeletal muscle mANC1 solute carrier family 25 member 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8 B1.1\|8 26.22 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_007450.4	NP_031476.3	ADP/ATP translocase 1
NM_007450.5	NP_031476.3	ADP/ATP translocase 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SLC25A4	NP_777083.1
Anopheles gambiae (African malaria mosquito)	ADT2_ANOGA	XP_003436097.1
Danio rerio (zebrafish)	slc25a4	NP_999867.1
Xenopus tropicalis (tropical clawed frog)	slc25a4	NP_988909.1
	SLC25A4	XP_001084544.1
Canis lupus familiaris (dog)	SLC25A4	XP_532844.2
Mus musculus (house mouse)	Slc25a4	NP_031476.3
Gallus gallus (chicken)	SLC25A4	NP_001006443.1
Drosophila melanogaster (fruit fly)	sesB	NP_727448.1
Homo sapiens (human)	SLC25A4	NP_001142.2
Pan troglodytes (chimpanzee)	SLC25A4	XP_517556.3
Rattus norvegicus (Norway rat)	Slc25a4	NP_445967.1

Gene Ontology
Bibliography

Related articles in PubMed

Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity.
Morrow RM, Picard M, Derbeneva O, Leipzig J, McManus MJ, Gouspillou G, Barbat-Artigas S, Dos Santos C, Hepple RT, Murdock DG, Wallace DC
Proceedings of the National Academy of Sciences of the United States of America114(10)2705-2710(2017 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ANT1 can induce autoimmune myocarditis in A/J mice by generating autoreactive T cells.
Title: Identification of an Epitope from Adenine Nucleotide Translocator 1 That Induces Inflammation in Heart in A/J Mice.

miR-2861 and ANT1 are regulators of cardiomyocyte necrosis and myocardial infarction.
Title: MicroRNA-2861 regulates programmed necrosis in cardiomyocyte by impairing adenine nucleotide translocase 1 expression.

Data indicate that palmitoyl-carnitine (PC) increases the type 2 ryanodine receptor (RyR2) oxidation and reduces the ATP/ADP translocase (ANT) activity.
Title: Palmitoyl-carnitine increases RyR2 oxidation and sarcoplasmic reticulum Ca2+ leak in cardiomyocytes: Role of adenine nucleotide translocase.

These results suggest that follicular helper T cells cells and IL-21 might be involved in the pathogenesis of viral myocarditis and play an important role in anti-ANT autoantibody production.
Title: Increased frequency of follicular helper T cells in mice viral myocarditis is relevant with anti-ANT antoantibody.

Downregulation of adenine nucleotide translocator 1 exacerbates tumor necrosis factor-alpha-mediated cardiac inflammatory responses.
Title: Downregulation of adenine nucleotide translocator 1 exacerbates tumor necrosis factor-?-mediated cardiac inflammatory responses.

The following Slc25a4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc25a4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu14911	NM_007450.5 Latest version!	Mus musculus solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 (Slc25a4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
View Old Accession Versions >>
OMu14911	NM_007450.4	Mus musculus solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 (Slc25a4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc25a4 ( NM_007450.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031476.3 Mus musculus solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 (Slc25a4), mRNA.

Price & Availability↑

CloneID	OMu14911
Clone ID Related Accession (Same CDS sequence)	NM_007450.4 , NM_007450.5
Accession Version	NM_007450.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 897bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Mus musculus(house mouse)
Product	ADP/ATP translocase 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC003791.1. On Jun 10, 2007 this sequence version replaced NM_007450.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC003791.1, AK078077.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END##

ATGGGGGATC AGGCTTTGAG CTTTCTTAAG GACTTCCTGG CAGGTGGCAT CGCCGCCGCC 
GTCTCCAAGA CGGCGGTCGC CCCGATCGAG AGGGTCAAAC TGCTGCTGCA GGTCCAGCAT 
GCCAGCAAAC AGATCAGTGC AGAGAAGCAG TACAAAGGCA TCATTGATTG TGTCGTGAGA 
ATCCCCAAGG AGCAGGGCTT TCTCTCTTTC TGGAGGGGTA ACCTGGCCAA CGTGATCCGG 
TACTTCCCCA CTCAAGCCCT GAACTTCGCC TTCAAAGACA AGTACAAGCA GATCTTCCTG 
GGAGGCGTGG ATCGCCATAA GCAGTTCTGG CGCTACTTTG CTGGTAACCT GGCCTCTGGT 
GGGGCAGCTG GGGCCACCTC CCTCTGCTTC GTCTACCCGC TGGACTTTGC TAGGACCAGG 
CTGGCTGCCG ACGTGGGCAA GGGATCTTCC CAGCGAGAAT TCAATGGGCT GGGCGACTGT 
CTCACCAAGA TCTTCAAGTC GGACGGCCTG AAGGGTCTCT ACCAGGGTTT CAGTGTCTCT 
GTCCAGGGCA TCATCATCTA CAGAGCTGCC TACTTCGGAG TCTATGACAC TGCCAAGGGG 
ATGCTGCCAG ACCCCAAGAA TGTGCACATT ATCGTGAGCT GGATGATTGC CCAGAGTGTG 
ACAGCGGTGG CGGGGCTGGT GTCCTATCCG TTTGACACTG TTCGTCGTAG GATGATGATG 
CAGTCTGGCC GGAAAGGGGC TGATATTATG TACACGGGGA CACTTGACTG CTGGAGGAAG 
ATTGCAAAAG ATGAAGGAGC CAACGCTTTC TTCAAAGGTG CTTGGTCCAA TGTACTGAGA 
GGCATGGGTG GTGCTTTTGT ATTGGTATTG TATGATGAGA TCAAAAAATA TGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031476.3
CDS	88..984
Translation	MGDQALSFLKDFLAGGIAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGSSQREFNGLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPDPKNVHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTLDCWRKIAKDEGANAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV

Target ORF information:

RefSeq Version	NM_007450.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 (Slc25a4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007450.4

ORF Insert Sequence:

ATGGGGGATC AGGCTTTGAG CTTTCTTAAG GACTTCCTGG CAGGTGGCAT CGCCGCCGCC 
GTCTCCAAGA CGGCGGTCGC CCCGATCGAG AGGGTCAAAC TGCTGCTGCA GGTCCAGCAT 
GCCAGCAAAC AGATCAGTGC AGAGAAGCAG TACAAAGGCA TCATTGATTG TGTCGTGAGA 
ATCCCCAAGG AGCAGGGCTT TCTCTCTTTC TGGAGGGGTA ACCTGGCCAA CGTGATCCGG 
TACTTCCCCA CTCAAGCCCT GAACTTCGCC TTCAAAGACA AGTACAAGCA GATCTTCCTG 
GGAGGCGTGG ATCGCCATAA GCAGTTCTGG CGCTACTTTG CTGGTAACCT GGCCTCTGGT 
GGGGCAGCTG GGGCCACCTC CCTCTGCTTC GTCTACCCGC TGGACTTTGC TAGGACCAGG 
CTGGCTGCCG ACGTGGGCAA GGGATCTTCC CAGCGAGAAT TCAATGGGCT GGGCGACTGT 
CTCACCAAGA TCTTCAAGTC GGACGGCCTG AAGGGTCTCT ACCAGGGTTT CAGTGTCTCT 
GTCCAGGGCA TCATCATCTA CAGAGCTGCC TACTTCGGAG TCTATGACAC TGCCAAGGGG 
ATGCTGCCAG ACCCCAAGAA TGTGCACATT ATCGTGAGCT GGATGATTGC CCAGAGTGTG 
ACAGCGGTGG CGGGGCTGGT GTCCTATCCG TTTGACACTG TTCGTCGTAG GATGATGATG 
CAGTCTGGCC GGAAAGGGGC TGATATTATG TACACGGGGA CACTTGACTG CTGGAGGAAG 
ATTGCAAAAG ATGAAGGAGC CAACGCTTTC TTCAAAGGTG CTTGGTCCAA TGTACTGAGA 
GGCATGGGTG GTGCTTTTGT ATTGGTATTG TATGATGAGA TCAAAAAATA TGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc25a4 ( NM_007450.5 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_031476.3 Mus musculus solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 (Slc25a4), mRNA.

Price & Availability↑

CloneID	OMu14911
Clone ID Related Accession (Same CDS sequence)	NM_007450.4 , NM_007450.5
Accession Version	NM_007450.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 897bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Mus musculus(house mouse)
Product	ADP/ATP translocase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC156551.5. On Mar 28, 2018 this sequence version replaced NM_007450.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660813.186775.1, AK078077.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGGATC AGGCTTTGAG CTTTCTTAAG GACTTCCTGG CAGGTGGCAT CGCCGCCGCC 
GTCTCCAAGA CGGCGGTCGC CCCGATCGAG AGGGTCAAAC TGCTGCTGCA GGTCCAGCAT 
GCCAGCAAAC AGATCAGTGC AGAGAAGCAG TACAAAGGCA TCATTGATTG TGTCGTGAGA 
ATCCCCAAGG AGCAGGGCTT TCTCTCTTTC TGGAGGGGTA ACCTGGCCAA CGTGATCCGG 
TACTTCCCCA CTCAAGCCCT GAACTTCGCC TTCAAAGACA AGTACAAGCA GATCTTCCTG 
GGAGGCGTGG ATCGCCATAA GCAGTTCTGG CGCTACTTTG CTGGTAACCT GGCCTCTGGT 
GGGGCAGCTG GGGCCACCTC CCTCTGCTTC GTCTACCCGC TGGACTTTGC TAGGACCAGG 
CTGGCTGCCG ACGTGGGCAA GGGATCTTCC CAGCGAGAAT TCAATGGGCT GGGCGACTGT 
CTCACCAAGA TCTTCAAGTC GGACGGCCTG AAGGGTCTCT ACCAGGGTTT CAGTGTCTCT 
GTCCAGGGCA TCATCATCTA CAGAGCTGCC TACTTCGGAG TCTATGACAC TGCCAAGGGG 
ATGCTGCCAG ACCCCAAGAA TGTGCACATT ATCGTGAGCT GGATGATTGC CCAGAGTGTG 
ACAGCGGTGG CGGGGCTGGT GTCCTATCCG TTTGACACTG TTCGTCGTAG GATGATGATG 
CAGTCTGGCC GGAAAGGGGC TGATATTATG TACACGGGGA CACTTGACTG CTGGAGGAAG 
ATTGCAAAAG ATGAAGGAGC CAACGCTTTC TTCAAAGGTG CTTGGTCCAA TGTACTGAGA 
GGCATGGGTG GTGCTTTTGT ATTGGTATTG TATGATGAGA TCAAAAAATA TGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031476.3
CDS	141..1037
Translation	MGDQALSFLKDFLAGGIAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGSSQREFNGLGDCLTKIFKSDGLKGLYQGFSVSVQGIIIYRAAYFGVYDTAKGMLPDPKNVHIIVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTLDCWRKIAKDEGANAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV

Target ORF information:

RefSeq Version	NM_007450.5
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 (Slc25a4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007450.5

ORF Insert Sequence:

ATGGGGGATC AGGCTTTGAG CTTTCTTAAG GACTTCCTGG CAGGTGGCAT CGCCGCCGCC 
GTCTCCAAGA CGGCGGTCGC CCCGATCGAG AGGGTCAAAC TGCTGCTGCA GGTCCAGCAT 
GCCAGCAAAC AGATCAGTGC AGAGAAGCAG TACAAAGGCA TCATTGATTG TGTCGTGAGA 
ATCCCCAAGG AGCAGGGCTT TCTCTCTTTC TGGAGGGGTA ACCTGGCCAA CGTGATCCGG 
TACTTCCCCA CTCAAGCCCT GAACTTCGCC TTCAAAGACA AGTACAAGCA GATCTTCCTG 
GGAGGCGTGG ATCGCCATAA GCAGTTCTGG CGCTACTTTG CTGGTAACCT GGCCTCTGGT 
GGGGCAGCTG GGGCCACCTC CCTCTGCTTC GTCTACCCGC TGGACTTTGC TAGGACCAGG 
CTGGCTGCCG ACGTGGGCAA GGGATCTTCC CAGCGAGAAT TCAATGGGCT GGGCGACTGT 
CTCACCAAGA TCTTCAAGTC GGACGGCCTG AAGGGTCTCT ACCAGGGTTT CAGTGTCTCT 
GTCCAGGGCA TCATCATCTA CAGAGCTGCC TACTTCGGAG TCTATGACAC TGCCAAGGGG 
ATGCTGCCAG ACCCCAAGAA TGTGCACATT ATCGTGAGCT GGATGATTGC CCAGAGTGTG 
ACAGCGGTGG CGGGGCTGGT GTCCTATCCG TTTGACACTG TTCGTCGTAG GATGATGATG 
CAGTCTGGCC GGAAAGGGGC TGATATTATG TACACGGGGA CACTTGACTG CTGGAGGAAG 
ATTGCAAAAG ATGAAGGAGC CAACGCTTTC TTCAAAGGTG CTTGGTCCAA TGTACTGAGA 
GGCATGGGTG GTGCTTTTGT ATTGGTATTG TATGATGAGA TCAAAAAATA TGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity.
Proceedings of the National Academy of Sciences of the United States of America114(10)2705-2710(2017 Mar)
Morrow RM,Picard M,Derbeneva O,Leipzig J,McManus MJ,Gouspillou G,Barbat-Artigas S,Dos Santos C,Hepple RT,Murdock DG,Wallace DC

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Slc25a4 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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