Gene Symbol | ISG15 |
Entrez Gene ID | 9636 |
Full Name | ISG15 ubiquitin-like modifier |
Synonyms | G1P2,IFI15,IMD38,IP17,UCRP,hUCRP |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. [provided by RefSeq, Dec 2012]. |
Disorder MIM: | |
Disorder Html: | Immunodeficiency 38, 616126 (3) |