Gene Symbol | MED25 |
Entrez Gene ID | 81857 |
Full Name | mediator complex subunit 25 |
Synonyms | ACID1,ARC92,BVSYS,CMT2B2,P78,PTOV2,TCBAP0758 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq, Apr 2010]. |
Disorder MIM: | |
Disorder Html: | ?Charcot-Marie-Tooth disease, type 2B2, 605589 (3); Basel-Vanagait-Smirin-Yosef syndrome, 616449 (3) |