Gene Symbol | OBFC1 |
Entrez Gene ID | 79991 |
Full Name | STN1, CST complex subunit |
Synonyms | AAF-44,AAF44,OBFC1,RPA-32,bA541N10.2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009 [PubMed 19119139]). OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1 (C17ORF106; MIM 613130) (Miyake et al., 2009 [PubMed 19854130]).[supplied by OMIM, Nov 2009]. |
Disorder MIM: | |
Disorder Html: | Cerebroretinal microangiopathy with calcifications and cysts 2, 617341 (3) |