Gene Symbol | AFDN |
Entrez Gene ID | 4301 |
Full Name | afadin, adherens junction formation factor |
Synonyms | AF6,MLL-AF6,MLLT4,l-afadin |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011]. |
Disorder MIM: |