Gene Symbol | BIRC3 |
Entrez Gene ID | 330 |
Full Name | baculoviral IAP repeat containing 3 |
Synonyms | AIP1,API2,CIAP2,HAIP1,HIAP1,MALT2,MIHC,RNF49,c-IAP2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]. |
Disorder MIM: |