Gene Symbol | EML4 |
Entrez Gene ID | 27436 |
Full Name | echinoderm microtubule associated protein like 4 |
Synonyms | C2orf2,ELP120,EMAP-4,EMAPL4,ROPP120 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015]. |
Disorder MIM: |