LRTOMT cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LRTOMT
Entrez Gene ID	220074
Full Name	leucine rich transmembrane and O-methyltransferase domain containing
Synonyms	CFAP111,DFNB63,LRRC51
General protein information	Preferred Names leucine rich transmembrane and O-methyltransferase domain containing Names transmembrane O-methyltransferase leucine-rich repeat-containing protein 51 leucine rich transmembrane and 0-methyltransferase domain containing
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q13.4
Summary	This gene has evolved in primates as a fusion of two ancestral neighboring genes, Lrrc51 and Tomt, which exist as two independent genes in rodents. The fusion gene contains some shared exons, but encodes structurally unrelated proteins, LRTOMT1 and LRTOMT2. Those variants that utilize the more centromere-proximal 3' terminal exon (short transcript form) encode LRTOMT1, while those variants that use a more centromere-distal 3' terminal exon (long transcript form) encode the LRTOMT2 protein. There is a small region within one of the exons of this gene that contains overlapping alternate reading frames for both LRTOMT1 and LRTOMT2. LRTOMT1 shares similarity with the protein encoded by mouse Lrrc51, while LRTOMT2 shares similarity with the protein encoded by mouse Tomt. Alternative splicing results in multiple transcript variants, encoding different isoforms of both LRTOMT1 and LRTOMT2. The LRTOMT1 protein is a leucine-rich repeat-containing protein, while the LRTOMT2 protein is a catechol-O-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to a hydroxyl group of catechols and is essential for auditory and vestibular function. Mutations in this gene have been associated with nonsyndromic deafness. [provided by RefSeq, Nov 2017].
Disorder MIM:	612414
Disorder Html:	Deafness, autosomal recessive 63, 611451 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001145309.3	NP_001138781.1	transmembrane O-methyltransferase isoform LRTOMT2a
XM_024448401.1	XP_024304169.1	transmembrane O-methyltransferase isoform X2
NM_145309.6	NP_660352.1	leucine-rich repeat-containing protein 51 isoform LRTOMT1a
NM_001145308.4	NP_001138780.1	transmembrane O-methyltransferase isoform LRTOMT2a
XM_017017356.1	XP_016872845.1	transmembrane O-methyltransferase isoform X1
XM_017017357.1	XP_016872846.1	transmembrane O-methyltransferase isoform X1
XM_011544847.2	XP_011543149.1	leucine-rich repeat-containing protein 51 isoform X2
XM_006718473.3	XP_006718536.1	leucine-rich repeat-containing protein 51 isoform X2
NM_145309.5	NP_660352.1	leucine-rich repeat-containing protein 51 isoform LRTOMT1a
XM_011544847.3	XP_011543149.1	leucine-rich repeat-containing protein 51 isoform X1
XM_006718474.4	XP_006718537.1	leucine-rich repeat-containing protein 51 isoform X1
NM_001145310.4	NP_001138782.1	transmembrane O-methyltransferase isoform LRTOMT2b
XM_017017360.1	XP_016872849.1	leucine-rich repeat-containing protein 51 isoform X2
NM_001205138.3	NP_001192067.1	leucine-rich repeat-containing protein 51 isoform LRTOMT1c
NM_001145307.4	NP_001138779.1	leucine-rich repeat-containing protein 51 isoform LRTOMT1b
NM_001318803.1	NP_001305732.1	transmembrane O-methyltransferase isoform LRTOMT1a
XM_006718473.4	XP_006718536.1	leucine-rich repeat-containing protein 51 isoform X1
NM_001145308.5	NP_001138780.1	transmembrane O-methyltransferase isoform LRTOMT2a
NM_001205138.4	NP_001192067.1	leucine-rich repeat-containing protein 51 isoform LRTOMT1c
NM_001145309.4	NP_001138781.1	transmembrane O-methyltransferase isoform LRTOMT2a
NM_001271471.3	NP_001258400.1	leucine-rich repeat-containing protein 51 isoform LRTOMT1d
XM_017017359.1	XP_016872848.1	leucine-rich repeat-containing protein 51 isoform X2
XM_006718474.3	XP_006718537.1	leucine-rich repeat-containing protein 51 isoform X2
NM_001271471.2	NP_001258400.1	leucine-rich repeat-containing protein 51 isoform LRTOMT1d
XM_011544848.3	XP_011543150.1	leucine-rich repeat-containing protein 51 isoform X1
NM_001318803.2	NP_001305732.1	transmembrane O-methyltransferase isoform LRTOMT1a
NM_001145310.3	NP_001138782.1	transmembrane O-methyltransferase isoform LRTOMT2b
XM_017017358.1	XP_016872847.1	transmembrane O-methyltransferase isoform X1
XM_011544848.2	XP_011543150.1	leucine-rich repeat-containing protein 51 isoform X2
NM_001145307.5	NP_001138779.1	leucine-rich repeat-containing protein 51 isoform LRTOMT1b

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TOMT	XP_002693495.2
	LRTOMT	NP_001129574.1
Mus musculus (house mouse)	Tomt	NP_001075148.1
Homo sapiens (human)	LRTOMT	NP_001138780.1
Pan troglodytes (chimpanzee)	LRTOMT	NP_001186282.1
Rattus norvegicus (Norway rat)	Tomt	NP_001132966.1
Xenopus tropicalis (tropical clawed frog)	LOC100490284	XP_002943748.1

Gene Ontology
Bibliography

Related articles in PubMed

Novel mutations in LRTOMT associated with moderate progressive hearing loss in autosomal recessive inheritance.
Ichinose A, Moteki H, Hattori M, Nishio SY, Usami S
The Annals of otology, rhinology, and laryngology124 Suppl 1142S-7S(2015 May)

The c.242G>A mutation in LRTOMT gene is responsible for a high prevalence of deafness in the Moroccan population.
Charif M, Bounaceur S, Abidi O, Nahili H, Rouba H, Kandil M, Boulouiz R, Barakat A
Molecular biology reports39(12)11011-6(2012 Dec)

A 1 bp deletion in the dual reading frame deafness gene LRTOMT causes a frameshift from the first into the second reading frame.
Vanwesemael M, Schrauwen I, Ceuppens R, Alasti F, Jorssen E, Farrokhi E, Chaleshtori MH, Van Camp G
American journal of medical genetics. Part A155A(8)2021-3(2011 Aug)

Mutations of LRTOMT, a fusion gene with alternative reading frames, cause nonsyndromic deafness in humans.
Ahmed ZM, Masmoudi S, Kalay E, Belyantseva IA, Mosrati MA, Collin RW, Riazuddin S, Hmani-Aifa M, Venselaar H, Kawar MN, Tlili A, van der Zwaag B, Khan SY, Ayadi L, Riazuddin SA, Morell RJ, Griffith AJ, Charfedine I, Caylan R, Oostrik J, Karaguzel A, Ghorbel A, Riazuddin S, Friedman TB, Ayadi H, Kremer H
Nature genetics40(11)1335-40(2008 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results indicate that mutations in the LRT)MT gene lead to alterations in the LRTOMT2 protein and might be involved in progressive sensorineural hearing loss.
Title: Novel mutations in LRTOMT associated with moderate progressive hearing loss in autosomal recessive inheritance.

LRTOMT gene is the second cause of congenital hearing impairment in Moroccan patients.
Title: The c.242G>A mutation in LRTOMT gene is responsible for a high prevalence of deafness in the Moroccan population.

A 1 bp deletion in the dual reading frame deafness gene LRTOMT causes a frameshift from the first into the second reading frame.
Title: A 1 bp deletion in the dual reading frame deafness gene LRTOMT causes a frameshift from the first into the second reading frame.

Mutations of LRTOMT are associated with profound nonsyndromic hearing loss at the DFNB63 locus on human chromosome 11q13.3-q13.4.
Title: Mutations of LRTOMT, a fusion gene with alternative reading frames, cause nonsyndromic deafness in humans.

nonsense mutation in the human ortholog of the murine Comt2 gene that causes nonsyndromic deafness
Title: A catechol-O-methyltransferase that is essential for auditory function in mice and humans.

The following LRTOMT gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LRTOMT cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06548	XM_017017359.1 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu06548	XM_006718473.4 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu06548	XM_006718474.4 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu06548	XM_011544847.3 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu06548	XM_011544848.3 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu06548	XM_017017360.1 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu02522	NM_001145307.5 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu02528	NM_001145309.4 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu02528	NM_001145308.5 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu06548	NM_145309.6 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu06548	NM_001318803.2 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu10974	NM_001271471.3 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu27517	NM_001145310.4 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu27571	NM_001205138.4 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu77952	XM_024448401.1 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu92035	XM_017017357.1 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu92035	XM_017017356.1 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu92035	XM_017017358.1 Latest version!	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu06548	NM_145309.5	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu06548	XM_011544847.2	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu06548	XM_006718473.3	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu02528	NM_001145308.4	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu27571	NM_001205138.3	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu02528	NM_001145309.3	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu06548	XM_006718474.3	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu10974	NM_001271471.2	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu06548	NM_001318803.1	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu27517	NM_001145310.3	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu06548	XM_011544848.2	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu02522	NM_001145307.4	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LRTOMT ( NM_001145307.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138779.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02522
Clone ID Related Accession (Same CDS sequence)	NM_001145307.4 , NM_001145307.5
Accession Version	NM_001145307.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform LRTOMT1b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1 and BC012855.1. On Oct 3, 2012 this sequence version replaced NM_001145307.3. Transcript Variant: This variant (2, also known as B) represents the short transcript form. It lacks a segment in the 3' exon, compared to variant 1. The resulting isoform (LRTOMT1b) is a LRR-containing protein, but has a shorter and distinct C-terminus, compared to isoform LRTOMT1a. This protein is supported by Western blot as reported in PMID:18953341. ##Evidence-Data-START## CDS exon combination :: EU627067.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGAGT ACCAGGGTCT GTAGAGATGC CTCACAGGCC TCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138779.1
CDS	695..1171
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRVPGSVEMPHRPP

Target ORF information:

RefSeq Version	NM_001145307.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145307.4

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGAGT ACCAGGGTCT GTAGAGATGC CTCACAGGCC TCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_001145309.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138781.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu02528
Clone ID Related Accession (Same CDS sequence)	NM_001145309.3 , NM_001145308.4 , NM_001145308.5 , NM_001145309.4
Accession Version	NM_001145309.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	transmembrane O-methyltransferase isoform LRTOMT2a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1, EU627069.1 and BX115135.1. On Oct 3, 2012 this sequence version replaced NM_001145309.2. Transcript Variant: This variant (5, also known as D') represents the long transcript form. It lacks the 3' terminal exon and includes several alternate exons, compared to variant 1. This variant encodes isoform LRTOMT2a, which is a transmembrane catechol-O-methyltransferase and is supported by Western blot as reported in PMID: 18953341. Variants 4 and 5 encode the same isoform LRTOMT2a. ##Evidence-Data-START## Transcript exon combination :: EU627069.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAACCC CATGGAGGAA GAGAAAGGGT ATAGCAGGCC CTGGACTCCC CGACCTGTCC 
TGTGCTCTGG TCCTCCAGCC CAGGGCCCAG GTAGGGACCA TGTCCCCTGC CATTGCATTG 
GCCTTCCTGC CACTGGTGGT AACATTGCTG GTGCGGTACC GGCACTACTT CCGATTGCTG 
GTGCGCACGG TCTTGCTGCG AAGCCTCCGA GACTGCCTGT CAGGGCTGCG GATCGAGGAG 
CGGGCCTTCA GCTACGTGCT CACCCATGCC CTGCCCGGTG ACCCTGGTCA CATCCTCACC 
ACCCTGGACC ACTGGAGCAG CCGCTGCGAG TACTTGAGCC ACATGGGGCC TGTCAAAGGT 
CAGATCCTGA TGCGGCTGGT GGAGGAGAAG GCCCCTGCTT GTGTGCTGGA ATTGGGAACC 
TACTGTGGAT ACTCTACCCT GCTTATTGCC CGAGCCCTGC CCCCTGGGGG TCGCCTTCTT 
ACTGTGGAGC GGGACCCACG CACGGCAGCA GTGGCTGAAA AACTCATCCG CCTGGCCGGC 
TTTGATGAGC ACATGGTGGA GCTCATCGTG GGCAGCTCAG AGGACGTGAT CCCGTGCCTA 
CGCACCCAGT ATCAGCTGAG TCGGGCAGAC CTGGTGCTCC TGGCACACCG GCCACGATGT 
TACCTGAGGG ACCTGCAGCT GCTGGAGGCC CATGCCCTAC TGCCAGCAGG TGCCACCGTG 
CTGGCTGACC ATGTGCTCTT CCCTGGTGCA CCCCGCTTCT TGCAGTATGC TAAGAGCTGT 
GGCCGCTACC GCTGCCGCCT CCACCACACT GGCCTTCCAG ACTTCCCTGC CATCAAGGAT 
GGAATAGCTC AGCTCACCTA TGCTGGACCA GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138781.1
CDS	1098..1973
Translation	MGTPWRKRKGIAGPGLPDLSCALVLQPRAQVGTMSPAIALAFLPLVVTLLVRYRHYFRLLVRTVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAGFDEHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATVLADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG

Target ORF information:

RefSeq Version	NM_001145309.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145309.3

ORF Insert Sequence:

ATGGGAACCC CATGGAGGAA GAGAAAGGGT ATAGCAGGCC CTGGACTCCC CGACCTGTCC 
TGTGCTCTGG TCCTCCAGCC CAGGGCCCAG GTAGGGACCA TGTCCCCTGC CATTGCATTG 
GCCTTCCTGC CACTGGTGGT AACATTGCTG GTGCGGTACC GGCACTACTT CCGATTGCTG 
GTGCGCACGG TCTTGCTGCG AAGCCTCCGA GACTGCCTGT CAGGGCTGCG GATCGAGGAG 
CGGGCCTTCA GCTACGTGCT CACCCATGCC CTGCCCGGTG ACCCTGGTCA CATCCTCACC 
ACCCTGGACC ACTGGAGCAG CCGCTGCGAG TACTTGAGCC ACATGGGGCC TGTCAAAGGT 
CAGATCCTGA TGCGGCTGGT GGAGGAGAAG GCCCCTGCTT GTGTGCTGGA ATTGGGAACC 
TACTGTGGAT ACTCTACCCT GCTTATTGCC CGAGCCCTGC CCCCTGGGGG TCGCCTTCTT 
ACTGTGGAGC GGGACCCACG CACGGCAGCA GTGGCTGAAA AACTCATCCG CCTGGCCGGC 
TTTGATGAGC ACATGGTGGA GCTCATCGTG GGCAGCTCAG AGGACGTGAT CCCGTGCCTA 
CGCACCCAGT ATCAGCTGAG TCGGGCAGAC CTGGTGCTCC TGGCACACCG GCCACGATGT 
TACCTGAGGG ACCTGCAGCT GCTGGAGGCC CATGCCCTAC TGCCAGCAGG TGCCACCGTG 
CTGGCTGACC ATGTGCTCTT CCCTGGTGCA CCCCGCTTCT TGCAGTATGC TAAGAGCTGT 
GGCCGCTACC GCTGCCGCCT CCACCACACT GGCCTTCCAG ACTTCCCTGC CATCAAGGAT 
GGAATAGCTC AGCTCACCTA TGCTGGACCA GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_001145308.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138780.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 4, mRNA.

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CloneID	OHu02528
Clone ID Related Accession (Same CDS sequence)	NM_001145309.3 , NM_001145308.4 , NM_001145308.5 , NM_001145309.4
Accession Version	NM_001145308.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	transmembrane O-methyltransferase isoform LRTOMT2a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1, AK302772.1, EU627069.1 and BX115135.1. This sequence is a reference standard in the RefSeqGene project. On Oct 3, 2012 this sequence version replaced NM_001145308.3. Transcript Variant: This variant (4) represents the long transcript form. It has multiple differences from variant 1. This variant lacks the upstream open reading frame as seen in the other variants of the long transcript form. The encoded isoform (LRTOMT2a) is a transmembrane catechol-O-methyltransferase. This protein is supported by Western blot as reported in PMID:18953341. Variants 4 and 5 encode the same isoform LRTOMT2a. ##Evidence-Data-START## Transcript exon combination :: AK302772.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAACCC CATGGAGGAA GAGAAAGGGT ATAGCAGGCC CTGGACTCCC CGACCTGTCC 
TGTGCTCTGG TCCTCCAGCC CAGGGCCCAG GTAGGGACCA TGTCCCCTGC CATTGCATTG 
GCCTTCCTGC CACTGGTGGT AACATTGCTG GTGCGGTACC GGCACTACTT CCGATTGCTG 
GTGCGCACGG TCTTGCTGCG AAGCCTCCGA GACTGCCTGT CAGGGCTGCG GATCGAGGAG 
CGGGCCTTCA GCTACGTGCT CACCCATGCC CTGCCCGGTG ACCCTGGTCA CATCCTCACC 
ACCCTGGACC ACTGGAGCAG CCGCTGCGAG TACTTGAGCC ACATGGGGCC TGTCAAAGGT 
CAGATCCTGA TGCGGCTGGT GGAGGAGAAG GCCCCTGCTT GTGTGCTGGA ATTGGGAACC 
TACTGTGGAT ACTCTACCCT GCTTATTGCC CGAGCCCTGC CCCCTGGGGG TCGCCTTCTT 
ACTGTGGAGC GGGACCCACG CACGGCAGCA GTGGCTGAAA AACTCATCCG CCTGGCCGGC 
TTTGATGAGC ACATGGTGGA GCTCATCGTG GGCAGCTCAG AGGACGTGAT CCCGTGCCTA 
CGCACCCAGT ATCAGCTGAG TCGGGCAGAC CTGGTGCTCC TGGCACACCG GCCACGATGT 
TACCTGAGGG ACCTGCAGCT GCTGGAGGCC CATGCCCTAC TGCCAGCAGG TGCCACCGTG 
CTGGCTGACC ATGTGCTCTT CCCTGGTGCA CCCCGCTTCT TGCAGTATGC TAAGAGCTGT 
GGCCGCTACC GCTGCCGCCT CCACCACACT GGCCTTCCAG ACTTCCCTGC CATCAAGGAT 
GGAATAGCTC AGCTCACCTA TGCTGGACCA GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138780.1
CDS	877..1752
Translation	MGTPWRKRKGIAGPGLPDLSCALVLQPRAQVGTMSPAIALAFLPLVVTLLVRYRHYFRLLVRTVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAGFDEHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATVLADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG

Target ORF information:

RefSeq Version	NM_001145308.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145308.4

ORF Insert Sequence:

ATGGGAACCC CATGGAGGAA GAGAAAGGGT ATAGCAGGCC CTGGACTCCC CGACCTGTCC 
TGTGCTCTGG TCCTCCAGCC CAGGGCCCAG GTAGGGACCA TGTCCCCTGC CATTGCATTG 
GCCTTCCTGC CACTGGTGGT AACATTGCTG GTGCGGTACC GGCACTACTT CCGATTGCTG 
GTGCGCACGG TCTTGCTGCG AAGCCTCCGA GACTGCCTGT CAGGGCTGCG GATCGAGGAG 
CGGGCCTTCA GCTACGTGCT CACCCATGCC CTGCCCGGTG ACCCTGGTCA CATCCTCACC 
ACCCTGGACC ACTGGAGCAG CCGCTGCGAG TACTTGAGCC ACATGGGGCC TGTCAAAGGT 
CAGATCCTGA TGCGGCTGGT GGAGGAGAAG GCCCCTGCTT GTGTGCTGGA ATTGGGAACC 
TACTGTGGAT ACTCTACCCT GCTTATTGCC CGAGCCCTGC CCCCTGGGGG TCGCCTTCTT 
ACTGTGGAGC GGGACCCACG CACGGCAGCA GTGGCTGAAA AACTCATCCG CCTGGCCGGC 
TTTGATGAGC ACATGGTGGA GCTCATCGTG GGCAGCTCAG AGGACGTGAT CCCGTGCCTA 
CGCACCCAGT ATCAGCTGAG TCGGGCAGAC CTGGTGCTCC TGGCACACCG GCCACGATGT 
TACCTGAGGG ACCTGCAGCT GCTGGAGGCC CATGCCCTAC TGCCAGCAGG TGCCACCGTG 
CTGGCTGACC ATGTGCTCTT CCCTGGTGCA CCCCGCTTCT TGCAGTATGC TAAGAGCTGT 
GGCCGCTACC GCTGCCGCCT CCACCACACT GGCCTTCCAG ACTTCCCTGC CATCAAGGAT 
GGAATAGCTC AGCTCACCTA TGCTGGACCA GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_145309.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_660352.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 1, mRNA.

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CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	NM_145309.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform LRTOMT1a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1 and BC012855.1. On Oct 3, 2012 this sequence version replaced NM_145309.4. Transcript Variant: This variant (1, also known as A) represents the short transcript form. It encodes the longest isoform (LRTOMT1a) of the leucine-rich repeat (LRR)-containing protein. This protein is supported by Western blot as reported in PMID:18953341. ##Evidence-Data-START## Transcript exon combination :: BC012855.1, SRR1803613.255983.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_660352.1
CDS	695..1273
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	NM_145309.5
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145309.5

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_001318803.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305732.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 9, mRNA.

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CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	NM_001318803.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	transmembrane O-methyltransferase isoform LRTOMT1a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1, BI461207.1 and EU627066.1. On Jan 14, 2016 this sequence version replaced XM_006718472.2. Transcript Variant: This variant (9, also known as A) differs in the 5' UTR compared to variant 1. It encodes the longest isoform (LRTOMT1a) of the leucine-rich repeat (LRR)-containing protein. This protein is supported by Western blot as reported in PMID:18953341. Variants 1 and 9 both encode the same isoform (LRTOMT1a). ##Evidence-Data-START## Transcript exon combination :: SRR1803617.116383.1, BI462037.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305732.1
CDS	652..1230
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	NM_001318803.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318803.1

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_001271471.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001258400.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 8, mRNA.

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CloneID	OHu10974
Clone ID Related Accession (Same CDS sequence)	NM_001271471.3 , NM_001271471.2
Accession Version	NM_001271471.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 441bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform LRTOMT1d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1, EU627068.1 and AP000812.4. On Oct 3, 2012 this sequence version replaced NM_001271471.1. Transcript Variant: This variant (8, also known as C) represents the short transcript form. It lacks a splice junction in the 3' region, which results in a longer transcript and immediate translation termination, compared to variant 1. The encoded isoform (LRTOMT1d) is a LRR-containing protein, but is truncated at the C-terminus, compared to isoform LRTOMT1a. This protein is supported by Western blot as reported in PMID:18953341. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: EU627068.1, SRR1803617.2258.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258400.1
CDS	695..1135
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYR

Target ORF information:

RefSeq Version	NM_001271471.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271471.2

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_001145310.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138782.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 6, mRNA.

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CloneID	OHu27517
Clone ID Related Accession (Same CDS sequence)	NM_001145310.4 , NM_001145310.3
Accession Version	NM_001145310.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 756bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	transmembrane O-methyltransferase isoform LRTOMT2b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1 and EU627070.1. On Oct 3, 2012 this sequence version replaced NM_001145310.2. Transcript Variant: This variant (6, also known as E') represents the long transcript form. It lacks the 3' terminal exon and includes several alternate exons, compared to variant 1. This variant encodes isoform LRTOMT2b, which lacks an internal segment including the transmembrane region, compared to isoform LRTOMT2a. Isoform LRTOMT2b is a catechol-O-methyltransferase, which is supported by Western blot as reported in PMID: 18953341. ##Evidence-Data-START## Transcript exon combination :: EU627070.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2151119 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAACCC CATGGAGGAA GAGAAAGGGT ATAGCAGGCC CTGGACTCCC CGACCTGTCC 
TGTGCTCTGG TCCTCCAGCC CAGCCTCCGA GACTGCCTGT CAGGGCTGCG GATCGAGGAG 
CGGGCCTTCA GCTACGTGCT CACCCATGCC CTGCCCGGTG ACCCTGGTCA CATCCTCACC 
ACCCTGGACC ACTGGAGCAG CCGCTGCGAG TACTTGAGCC ACATGGGGCC TGTCAAAGGT 
CAGATCCTGA TGCGGCTGGT GGAGGAGAAG GCCCCTGCTT GTGTGCTGGA ATTGGGAACC 
TACTGTGGAT ACTCTACCCT GCTTATTGCC CGAGCCCTGC CCCCTGGGGG TCGCCTTCTT 
ACTGTGGAGC GGGACCCACG CACGGCAGCA GTGGCTGAAA AACTCATCCG CCTGGCCGGC 
TTTGATGAGC ACATGGTGGA GCTCATCGTG GGCAGCTCAG AGGACGTGAT CCCGTGCCTA 
CGCACCCAGT ATCAGCTGAG TCGGGCAGAC CTGGTGCTCC TGGCACACCG GCCACGATGT 
TACCTGAGGG ACCTGCAGCT GCTGGAGGCC CATGCCCTAC TGCCAGCAGG TGCCACCGTG 
CTGGCTGACC ATGTGCTCTT CCCTGGTGCA CCCCGCTTCT TGCAGTATGC TAAGAGCTGT 
GGCCGCTACC GCTGCCGCCT CCACCACACT GGCCTTCCAG ACTTCCCTGC CATCAAGGAT 
GGAATAGCTC AGCTCACCTA TGCTGGACCA GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138782.1
CDS	1098..1853
Translation	MGTPWRKRKGIAGPGLPDLSCALVLQPSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAGFDEHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATVLADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG

Target ORF information:

RefSeq Version	NM_001145310.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145310.3

ORF Insert Sequence:

ATGGGAACCC CATGGAGGAA GAGAAAGGGT ATAGCAGGCC CTGGACTCCC CGACCTGTCC 
TGTGCTCTGG TCCTCCAGCC CAGCCTCCGA GACTGCCTGT CAGGGCTGCG GATCGAGGAG 
CGGGCCTTCA GCTACGTGCT CACCCATGCC CTGCCCGGTG ACCCTGGTCA CATCCTCACC 
ACCCTGGACC ACTGGAGCAG CCGCTGCGAG TACTTGAGCC ACATGGGGCC TGTCAAAGGT 
CAGATCCTGA TGCGGCTGGT GGAGGAGAAG GCCCCTGCTT GTGTGCTGGA ATTGGGAACC 
TACTGTGGAT ACTCTACCCT GCTTATTGCC CGAGCCCTGC CCCCTGGGGG TCGCCTTCTT 
ACTGTGGAGC GGGACCCACG CACGGCAGCA GTGGCTGAAA AACTCATCCG CCTGGCCGGC 
TTTGATGAGC ACATGGTGGA GCTCATCGTG GGCAGCTCAG AGGACGTGAT CCCGTGCCTA 
CGCACCCAGT ATCAGCTGAG TCGGGCAGAC CTGGTGCTCC TGGCACACCG GCCACGATGT 
TACCTGAGGG ACCTGCAGCT GCTGGAGGCC CATGCCCTAC TGCCAGCAGG TGCCACCGTG 
CTGGCTGACC ATGTGCTCTT CCCTGGTGCA CCCCGCTTCT TGCAGTATGC TAAGAGCTGT 
GGCCGCTACC GCTGCCGCCT CCACCACACT GGCCTTCCAG ACTTCCCTGC CATCAAGGAT 
GGAATAGCTC AGCTCACCTA TGCTGGACCA GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_001205138.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001192067.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu27571
Clone ID Related Accession (Same CDS sequence)	NM_001205138.3 , NM_001205138.4
Accession Version	NM_001205138.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 525bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform LRTOMT1c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1 and BC012855.1. On Oct 3, 2012 this sequence version replaced NM_001205138.2. Transcript Variant: This variant (7) represents the short transcript form. It lacks the exon containing the expected translation start codon, compared to variant 1. This difference results in an upstream translation start codon and the encoded isoform (LRTOMT1c) is a LRR-containing protein, but has a shorter and distinct N-terminus, compared to isoform LRTOMT1a. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.254700.1, SRR1803620.3879.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGGAGT TTCAGCCATC AGTGACAGAT CTGGTAAATG AGGAGCCAAG GACAGGACTA 
CGACCACTGA AGCGTTCAAA GTCGGGGAAA TCACTGACCC AGTCCCTGTG GCTGAATAAC 
AATGTTCTCA ATGATCTGAG AGACTTCAAC CAGGTGGCTT CACAGCTGTT GGAGCACCCA 
GAGAACCTGG CCTGGATCGA CCTGTCCTTT AATGACCTGA CTTCCATTGA CCCTGTCCTA 
ACAACTTTCT TCAACCTGAG TGTCCTCTAT CTTCACGGCA ACAGCATCCA GCGCCTGGGG 
GAGGTGAATA AGCTGGCTGT CCTTCCTCGG CTCCGTAGCC TGACACTCCA TGGGAACCCC 
ATGGAGGAAG AGAAAGGGTA TAGGCAATAT GTGCTGTGCA CCCTGTCCCG TATCACCACG 
TTCGACTTCA GTGGGGTCAC CAAAGCAGAC CGCACCACAG CTGAAGTCTG GAAACGCATG 
AACATCAAGC CCAAGAAGGC CTGGACCAAG CAGAATACAC TTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001192067.1
CDS	612..1136
Translation	MVEFQPSVTDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	NM_001205138.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001205138.3

ORF Insert Sequence:

ATGGTGGAGT TTCAGCCATC AGTGACAGAT CTGGTAAATG AGGAGCCAAG GACAGGACTA 
CGACCACTGA AGCGTTCAAA GTCGGGGAAA TCACTGACCC AGTCCCTGTG GCTGAATAAC 
AATGTTCTCA ATGATCTGAG AGACTTCAAC CAGGTGGCTT CACAGCTGTT GGAGCACCCA 
GAGAACCTGG CCTGGATCGA CCTGTCCTTT AATGACCTGA CTTCCATTGA CCCTGTCCTA 
ACAACTTTCT TCAACCTGAG TGTCCTCTAT CTTCACGGCA ACAGCATCCA GCGCCTGGGG 
GAGGTGAATA AGCTGGCTGT CCTTCCTCGG CTCCGTAGCC TGACACTCCA TGGGAACCCC 
ATGGAGGAAG AGAAAGGGTA TAGGCAATAT GTGCTGTGCA CCCTGTCCCG TATCACCACG 
TTCGACTTCA GTGGGGTCAC CAAAGCAGAC CGCACCACAG CTGAAGTCTG GAAACGCATG 
AACATCAAGC CCAAGAAGGC CTGGACCAAG CAGAATACAC TTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_011544847.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011543149.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	XM_011544847.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011544847.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543149.1
CDS	1149..1727
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	XM_011544847.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011544847.2

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_006718473.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006718536.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X7, mRNA.

Price & Availability↑

CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	XM_006718473.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006718473.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006718536.1
CDS	921..1499
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	XM_006718473.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006718473.3

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_011544847.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011543149.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	XM_011544847.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011544847.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543149.1
CDS	325..903
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	XM_011544847.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011544847.3

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_006718474.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_006718537.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	XM_006718474.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006718474.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006718537.1
CDS	600..1178
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	XM_006718474.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006718474.4

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_017017360.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016872849.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X8, mRNA.

Price & Availability↑

CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	XM_017017360.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016872849.1
CDS	1164..1742
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	XM_017017360.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017360.1

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_006718473.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_006718536.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	XM_006718473.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006718473.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006718536.1
CDS	229..807
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	XM_006718473.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006718473.4

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_017017359.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016872848.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	XM_017017359.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016872848.1
CDS	1312..1890
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	XM_017017359.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017359.1

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_006718474.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006718537.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X9, mRNA.

Price & Availability↑

CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	XM_006718474.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006718474.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006718537.1
CDS	960..1538
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	XM_006718474.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006718474.3

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_011544848.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011543150.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	XM_011544848.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011544848.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543150.1
CDS	589..1167
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	XM_011544848.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011544848.3

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_011544848.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011543150.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	XM_011544848.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011544848.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011543150.1
CDS	1207..1785
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	XM_011544848.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011544848.2

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_001145307.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138779.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 2, mRNA.

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CloneID	OHu02522
Clone ID Related Accession (Same CDS sequence)	NM_001145307.4 , NM_001145307.5
Accession Version	NM_001145307.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-29
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform LRTOMT1b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1 and BC012855.1. On Nov 30, 2019 this sequence version replaced NM_001145307.4. Transcript Variant: This variant (2, also known as B) represents the short transcript form. It lacks a segment in the 3' exon, compared to variant 1. The resulting isoform (LRTOMT1b) is a LRR-containing protein, but has a shorter and distinct C-terminus, compared to isoform LRTOMT1a. This protein is supported by Western blot as reported in PMID:18953341. ##Evidence-Data-START## Transcript exon combination :: ERR3218367.1430392.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGAGT ACCAGGGTCT GTAGAGATGC CTCACAGGCC TCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138779.1
CDS	176..652
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRVPGSVEMPHRPP

Target ORF information:

RefSeq Version	NM_001145307.5
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145307.5

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGAGT ACCAGGGTCT GTAGAGATGC CTCACAGGCC TCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_001145308.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138780.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 4, mRNA.

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CloneID	OHu02528
Clone ID Related Accession (Same CDS sequence)	NM_001145309.3 , NM_001145308.4 , NM_001145308.5 , NM_001145309.4
Accession Version	NM_001145308.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-29
Organism	Homo sapiens(human)
Product	transmembrane O-methyltransferase isoform LRTOMT2a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK302772.1, EU627069.1 and BX115135.1. On Nov 30, 2019 this sequence version replaced NM_001145308.4. Transcript Variant: This variant (4) represents the long transcript form. It has multiple differences from variant 1. This variant lacks the upstream open reading frame as seen in the other variants of the long transcript form. The encoded isoform (LRTOMT2a) is a transmembrane catechol-O-methyltransferase. This protein is supported by Western blot as reported in PMID:18953341. Variants 4 and 5 encode the same isoform LRTOMT2a. ##Evidence-Data-START## Transcript exon combination :: AK302772.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAACCC CATGGAGGAA GAGAAAGGGT ATAGCAGGCC CTGGACTCCC CGACCTGTCC 
TGTGCTCTGG TCCTCCAGCC CAGGGCCCAG GTAGGGACCA TGTCCCCTGC CATTGCATTG 
GCCTTCCTGC CACTGGTGGT AACATTGCTG GTGCGGTACC GGCACTACTT CCGATTGCTG 
GTGCGCACGG TCTTGCTGCG AAGCCTCCGA GACTGCCTGT CAGGGCTGCG GATCGAGGAG 
CGGGCCTTCA GCTACGTGCT CACCCATGCC CTGCCCGGTG ACCCTGGTCA CATCCTCACC 
ACCCTGGACC ACTGGAGCAG CCGCTGCGAG TACTTGAGCC ACATGGGGCC TGTCAAAGGT 
CAGATCCTGA TGCGGCTGGT GGAGGAGAAG GCCCCTGCTT GTGTGCTGGA ATTGGGAACC 
TACTGTGGAT ACTCTACCCT GCTTATTGCC CGAGCCCTGC CCCCTGGGGG TCGCCTTCTT 
ACTGTGGAGC GGGACCCACG CACGGCAGCA GTGGCTGAAA AACTCATCCG CCTGGCCGGC 
TTTGATGAGC ACATGGTGGA GCTCATCGTG GGCAGCTCAG AGGACGTGAT CCCGTGCCTA 
CGCACCCAGT ATCAGCTGAG TCGGGCAGAC CTGGTGCTCC TGGCACACCG GCCACGATGT 
TACCTGAGGG ACCTGCAGCT GCTGGAGGCC CATGCCCTAC TGCCAGCAGG TGCCACCGTG 
CTGGCTGACC ATGTGCTCTT CCCTGGTGCA CCCCGCTTCT TGCAGTATGC TAAGAGCTGT 
GGCCGCTACC GCTGCCGCCT CCACCACACT GGCCTTCCAG ACTTCCCTGC CATCAAGGAT 
GGAATAGCTC AGCTCACCTA TGCTGGACCA GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138780.1
CDS	358..1233
Translation	MGTPWRKRKGIAGPGLPDLSCALVLQPRAQVGTMSPAIALAFLPLVVTLLVRYRHYFRLLVRTVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAGFDEHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATVLADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG

Target ORF information:

RefSeq Version	NM_001145308.5
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145308.5

ORF Insert Sequence:

ATGGGAACCC CATGGAGGAA GAGAAAGGGT ATAGCAGGCC CTGGACTCCC CGACCTGTCC 
TGTGCTCTGG TCCTCCAGCC CAGGGCCCAG GTAGGGACCA TGTCCCCTGC CATTGCATTG 
GCCTTCCTGC CACTGGTGGT AACATTGCTG GTGCGGTACC GGCACTACTT CCGATTGCTG 
GTGCGCACGG TCTTGCTGCG AAGCCTCCGA GACTGCCTGT CAGGGCTGCG GATCGAGGAG 
CGGGCCTTCA GCTACGTGCT CACCCATGCC CTGCCCGGTG ACCCTGGTCA CATCCTCACC 
ACCCTGGACC ACTGGAGCAG CCGCTGCGAG TACTTGAGCC ACATGGGGCC TGTCAAAGGT 
CAGATCCTGA TGCGGCTGGT GGAGGAGAAG GCCCCTGCTT GTGTGCTGGA ATTGGGAACC 
TACTGTGGAT ACTCTACCCT GCTTATTGCC CGAGCCCTGC CCCCTGGGGG TCGCCTTCTT 
ACTGTGGAGC GGGACCCACG CACGGCAGCA GTGGCTGAAA AACTCATCCG CCTGGCCGGC 
TTTGATGAGC ACATGGTGGA GCTCATCGTG GGCAGCTCAG AGGACGTGAT CCCGTGCCTA 
CGCACCCAGT ATCAGCTGAG TCGGGCAGAC CTGGTGCTCC TGGCACACCG GCCACGATGT 
TACCTGAGGG ACCTGCAGCT GCTGGAGGCC CATGCCCTAC TGCCAGCAGG TGCCACCGTG 
CTGGCTGACC ATGTGCTCTT CCCTGGTGCA CCCCGCTTCT TGCAGTATGC TAAGAGCTGT 
GGCCGCTACC GCTGCCGCCT CCACCACACT GGCCTTCCAG ACTTCCCTGC CATCAAGGAT 
GGAATAGCTC AGCTCACCTA TGCTGGACCA GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_001145309.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138781.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 5, mRNA.

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CloneID	OHu02528
Clone ID Related Accession (Same CDS sequence)	NM_001145309.3 , NM_001145308.4 , NM_001145308.5 , NM_001145309.4
Accession Version	NM_001145309.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-29
Organism	Homo sapiens(human)
Product	transmembrane O-methyltransferase isoform LRTOMT2a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1, EU627069.1 and BX115135.1. On Nov 30, 2019 this sequence version replaced NM_001145309.3. Transcript Variant: This variant (5, also known as D') represents the long transcript form. It lacks the 3' terminal exon and includes several alternate exons, compared to variant 1. This variant encodes isoform LRTOMT2a, which is a transmembrane catechol-O-methyltransferase and is supported by Western blot as reported in PMID: 18953341. Variants 4 and 5 encode the same isoform LRTOMT2a. ##Evidence-Data-START## Transcript exon combination :: EU627069.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAACCC CATGGAGGAA GAGAAAGGGT ATAGCAGGCC CTGGACTCCC CGACCTGTCC 
TGTGCTCTGG TCCTCCAGCC CAGGGCCCAG GTAGGGACCA TGTCCCCTGC CATTGCATTG 
GCCTTCCTGC CACTGGTGGT AACATTGCTG GTGCGGTACC GGCACTACTT CCGATTGCTG 
GTGCGCACGG TCTTGCTGCG AAGCCTCCGA GACTGCCTGT CAGGGCTGCG GATCGAGGAG 
CGGGCCTTCA GCTACGTGCT CACCCATGCC CTGCCCGGTG ACCCTGGTCA CATCCTCACC 
ACCCTGGACC ACTGGAGCAG CCGCTGCGAG TACTTGAGCC ACATGGGGCC TGTCAAAGGT 
CAGATCCTGA TGCGGCTGGT GGAGGAGAAG GCCCCTGCTT GTGTGCTGGA ATTGGGAACC 
TACTGTGGAT ACTCTACCCT GCTTATTGCC CGAGCCCTGC CCCCTGGGGG TCGCCTTCTT 
ACTGTGGAGC GGGACCCACG CACGGCAGCA GTGGCTGAAA AACTCATCCG CCTGGCCGGC 
TTTGATGAGC ACATGGTGGA GCTCATCGTG GGCAGCTCAG AGGACGTGAT CCCGTGCCTA 
CGCACCCAGT ATCAGCTGAG TCGGGCAGAC CTGGTGCTCC TGGCACACCG GCCACGATGT 
TACCTGAGGG ACCTGCAGCT GCTGGAGGCC CATGCCCTAC TGCCAGCAGG TGCCACCGTG 
CTGGCTGACC ATGTGCTCTT CCCTGGTGCA CCCCGCTTCT TGCAGTATGC TAAGAGCTGT 
GGCCGCTACC GCTGCCGCCT CCACCACACT GGCCTTCCAG ACTTCCCTGC CATCAAGGAT 
GGAATAGCTC AGCTCACCTA TGCTGGACCA GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138781.1
CDS	579..1454
Translation	MGTPWRKRKGIAGPGLPDLSCALVLQPRAQVGTMSPAIALAFLPLVVTLLVRYRHYFRLLVRTVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAGFDEHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATVLADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG

Target ORF information:

RefSeq Version	NM_001145309.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145309.4

ORF Insert Sequence:

ATGGGAACCC CATGGAGGAA GAGAAAGGGT ATAGCAGGCC CTGGACTCCC CGACCTGTCC 
TGTGCTCTGG TCCTCCAGCC CAGGGCCCAG GTAGGGACCA TGTCCCCTGC CATTGCATTG 
GCCTTCCTGC CACTGGTGGT AACATTGCTG GTGCGGTACC GGCACTACTT CCGATTGCTG 
GTGCGCACGG TCTTGCTGCG AAGCCTCCGA GACTGCCTGT CAGGGCTGCG GATCGAGGAG 
CGGGCCTTCA GCTACGTGCT CACCCATGCC CTGCCCGGTG ACCCTGGTCA CATCCTCACC 
ACCCTGGACC ACTGGAGCAG CCGCTGCGAG TACTTGAGCC ACATGGGGCC TGTCAAAGGT 
CAGATCCTGA TGCGGCTGGT GGAGGAGAAG GCCCCTGCTT GTGTGCTGGA ATTGGGAACC 
TACTGTGGAT ACTCTACCCT GCTTATTGCC CGAGCCCTGC CCCCTGGGGG TCGCCTTCTT 
ACTGTGGAGC GGGACCCACG CACGGCAGCA GTGGCTGAAA AACTCATCCG CCTGGCCGGC 
TTTGATGAGC ACATGGTGGA GCTCATCGTG GGCAGCTCAG AGGACGTGAT CCCGTGCCTA 
CGCACCCAGT ATCAGCTGAG TCGGGCAGAC CTGGTGCTCC TGGCACACCG GCCACGATGT 
TACCTGAGGG ACCTGCAGCT GCTGGAGGCC CATGCCCTAC TGCCAGCAGG TGCCACCGTG 
CTGGCTGACC ATGTGCTCTT CCCTGGTGCA CCCCGCTTCT TGCAGTATGC TAAGAGCTGT 
GGCCGCTACC GCTGCCGCCT CCACCACACT GGCCTTCCAG ACTTCCCTGC CATCAAGGAT 
GGAATAGCTC AGCTCACCTA TGCTGGACCA GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_145309.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_660352.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 1, mRNA.

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CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	NM_145309.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform LRTOMT1a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1 and BC012855.1. On Nov 30, 2019 this sequence version replaced NM_145309.5. Transcript Variant: This variant (1, also known as A) represents the short transcript form. It encodes the longest isoform (LRTOMT1a) of the leucine-rich repeat (LRR)-containing protein. This protein is supported by Western blot as reported in PMID:18953341. ##Evidence-Data-START## Transcript exon combination :: EU627066.1, BC012855.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_660352.1
CDS	176..754
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	NM_145309.6
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145309.6

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_001318803.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305732.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 9, mRNA.

Price & Availability↑

CloneID	OHu06548
Clone ID Related Accession (Same CDS sequence)	NM_145309.6 , XM_011544847.2 , XM_006718473.3 , NM_145309.5 , XM_011544847.3 , XM_006718474.4 , XM_017017360.1 , NM_001318803.1 , XM_006718473.4 , XM_017017359.1 , XM_006718474.3 , XM_011544848.3 , NM_001318803.2 , XM_011544848.2
Accession Version	NM_001318803.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-29
Organism	Homo sapiens(human)
Product	transmembrane O-methyltransferase isoform LRTOMT1a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI461207.1 and EU627066.1. On Nov 30, 2019 this sequence version replaced NM_001318803.1. Transcript Variant: This variant (9, also known as A) differs in the 5' UTR compared to variant 1. It encodes the longest isoform (LRTOMT1a) of the leucine-rich repeat (LRR)-containing protein. This protein is supported by Western blot as reported in PMID:18953341. Variants 1 and 9 both encode the same isoform (LRTOMT1a). ##Evidence-Data-START## Transcript exon combination :: SRR1803617.116383.1, BI461207.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305732.1
CDS	133..711
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	NM_001318803.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318803.2

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGCA ATATGTGCTG TGCACCCTGT CCCGTATCAC CACGTTCGAC 
TTCAGTGGGG TCACCAAAGC AGACCGCACC ACAGCTGAAG TCTGGAAACG CATGAACATC 
AAGCCCAAGA AGGCCTGGAC CAAGCAGAAT ACACTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_001271471.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001258400.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 8, mRNA.

Price & Availability↑

CloneID	OHu10974
Clone ID Related Accession (Same CDS sequence)	NM_001271471.3 , NM_001271471.2
Accession Version	NM_001271471.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 441bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-29
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform LRTOMT1d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1, EU627068.1 and AP000812.4. On Nov 30, 2019 this sequence version replaced NM_001271471.2. Transcript Variant: This variant (8, also known as C) represents the short transcript form. It lacks a splice junction in the 3' region, which results in a longer transcript and immediate translation termination, compared to variant 1. The encoded isoform (LRTOMT1d) is a LRR-containing protein, but is truncated at the C-terminus, compared to isoform LRTOMT1a. This protein is supported by Western blot as reported in PMID:18953341. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: EU627068.1, SRR7346977.1097340.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258400.1
CDS	176..616
Translation	MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYR

Target ORF information:

RefSeq Version	NM_001271471.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271471.3

ORF Insert Sequence:

ATGAACAAAC GGGACTATAT GAACACTTCG GTACAGGAGC CCCCTCTTGA CTACTCCTTC 
AGAAGCATCC ACGTCATTCA AGATCTGGTA AATGAGGAGC CAAGGACAGG ACTACGACCA 
CTGAAGCGTT CAAAGTCGGG GAAATCACTG ACCCAGTCCC TGTGGCTGAA TAACAATGTT 
CTCAATGATC TGAGAGACTT CAACCAGGTG GCTTCACAGC TGTTGGAGCA CCCAGAGAAC 
CTGGCCTGGA TCGACCTGTC CTTTAATGAC CTGACTTCCA TTGACCCTGT CCTAACAACT 
TTCTTCAACC TGAGTGTCCT CTATCTTCAC GGCAACAGCA TCCAGCGCCT GGGGGAGGTG 
AATAAGCTGG CTGTCCTTCC TCGGCTCCGT AGCCTGACAC TCCATGGGAA CCCCATGGAG 
GAAGAGAAAG GGTATAGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_001145310.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138782.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 6, mRNA.

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CloneID	OHu27517
Clone ID Related Accession (Same CDS sequence)	NM_001145310.4 , NM_001145310.3
Accession Version	NM_001145310.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 756bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-29
Organism	Homo sapiens(human)
Product	transmembrane O-methyltransferase isoform LRTOMT2b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1 and EU627070.1. On Nov 30, 2019 this sequence version replaced NM_001145310.3. Transcript Variant: This variant (6, also known as E') represents the long transcript form. It lacks the 3' terminal exon and includes several alternate exons, compared to variant 1. This variant encodes isoform LRTOMT2b, which lacks an internal segment including the transmembrane region, compared to isoform LRTOMT2a. Isoform LRTOMT2b is a catechol-O-methyltransferase, which is supported by Western blot as reported in PMID: 18953341. ##Evidence-Data-START## Transcript exon combination :: EU627070.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAACCC CATGGAGGAA GAGAAAGGGT ATAGCAGGCC CTGGACTCCC CGACCTGTCC 
TGTGCTCTGG TCCTCCAGCC CAGCCTCCGA GACTGCCTGT CAGGGCTGCG GATCGAGGAG 
CGGGCCTTCA GCTACGTGCT CACCCATGCC CTGCCCGGTG ACCCTGGTCA CATCCTCACC 
ACCCTGGACC ACTGGAGCAG CCGCTGCGAG TACTTGAGCC ACATGGGGCC TGTCAAAGGT 
CAGATCCTGA TGCGGCTGGT GGAGGAGAAG GCCCCTGCTT GTGTGCTGGA ATTGGGAACC 
TACTGTGGAT ACTCTACCCT GCTTATTGCC CGAGCCCTGC CCCCTGGGGG TCGCCTTCTT 
ACTGTGGAGC GGGACCCACG CACGGCAGCA GTGGCTGAAA AACTCATCCG CCTGGCCGGC 
TTTGATGAGC ACATGGTGGA GCTCATCGTG GGCAGCTCAG AGGACGTGAT CCCGTGCCTA 
CGCACCCAGT ATCAGCTGAG TCGGGCAGAC CTGGTGCTCC TGGCACACCG GCCACGATGT 
TACCTGAGGG ACCTGCAGCT GCTGGAGGCC CATGCCCTAC TGCCAGCAGG TGCCACCGTG 
CTGGCTGACC ATGTGCTCTT CCCTGGTGCA CCCCGCTTCT TGCAGTATGC TAAGAGCTGT 
GGCCGCTACC GCTGCCGCCT CCACCACACT GGCCTTCCAG ACTTCCCTGC CATCAAGGAT 
GGAATAGCTC AGCTCACCTA TGCTGGACCA GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138782.1
CDS	579..1334
Translation	MGTPWRKRKGIAGPGLPDLSCALVLQPSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAGFDEHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATVLADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG

Target ORF information:

RefSeq Version	NM_001145310.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145310.4

ORF Insert Sequence:

ATGGGAACCC CATGGAGGAA GAGAAAGGGT ATAGCAGGCC CTGGACTCCC CGACCTGTCC 
TGTGCTCTGG TCCTCCAGCC CAGCCTCCGA GACTGCCTGT CAGGGCTGCG GATCGAGGAG 
CGGGCCTTCA GCTACGTGCT CACCCATGCC CTGCCCGGTG ACCCTGGTCA CATCCTCACC 
ACCCTGGACC ACTGGAGCAG CCGCTGCGAG TACTTGAGCC ACATGGGGCC TGTCAAAGGT 
CAGATCCTGA TGCGGCTGGT GGAGGAGAAG GCCCCTGCTT GTGTGCTGGA ATTGGGAACC 
TACTGTGGAT ACTCTACCCT GCTTATTGCC CGAGCCCTGC CCCCTGGGGG TCGCCTTCTT 
ACTGTGGAGC GGGACCCACG CACGGCAGCA GTGGCTGAAA AACTCATCCG CCTGGCCGGC 
TTTGATGAGC ACATGGTGGA GCTCATCGTG GGCAGCTCAG AGGACGTGAT CCCGTGCCTA 
CGCACCCAGT ATCAGCTGAG TCGGGCAGAC CTGGTGCTCC TGGCACACCG GCCACGATGT 
TACCTGAGGG ACCTGCAGCT GCTGGAGGCC CATGCCCTAC TGCCAGCAGG TGCCACCGTG 
CTGGCTGACC ATGTGCTCTT CCCTGGTGCA CCCCGCTTCT TGCAGTATGC TAAGAGCTGT 
GGCCGCTACC GCTGCCGCCT CCACCACACT GGCCTTCCAG ACTTCCCTGC CATCAAGGAT 
GGAATAGCTC AGCTCACCTA TGCTGGACCA GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( NM_001205138.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001192067.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 7, mRNA.

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CloneID	OHu27571
Clone ID Related Accession (Same CDS sequence)	NM_001205138.3 , NM_001205138.4
Accession Version	NM_001205138.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 525bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-29
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 51 isoform LRTOMT1c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA151871.1 and BC012855.1. On Nov 30, 2019 this sequence version replaced NM_001205138.3. Transcript Variant: This variant (7) represents the short transcript form. It lacks the exon containing the expected translation start codon, compared to variant 1. This difference results in an upstream translation start codon and the encoded isoform (LRTOMT1c) is a LRR-containing protein, but has a shorter and distinct N-terminus, compared to isoform LRTOMT1a. ##Evidence-Data-START## Transcript exon combination :: AK298997.1, SRR1803620.3879.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGGAGT TTCAGCCATC AGTGACAGAT CTGGTAAATG AGGAGCCAAG GACAGGACTA 
CGACCACTGA AGCGTTCAAA GTCGGGGAAA TCACTGACCC AGTCCCTGTG GCTGAATAAC 
AATGTTCTCA ATGATCTGAG AGACTTCAAC CAGGTGGCTT CACAGCTGTT GGAGCACCCA 
GAGAACCTGG CCTGGATCGA CCTGTCCTTT AATGACCTGA CTTCCATTGA CCCTGTCCTA 
ACAACTTTCT TCAACCTGAG TGTCCTCTAT CTTCACGGCA ACAGCATCCA GCGCCTGGGG 
GAGGTGAATA AGCTGGCTGT CCTTCCTCGG CTCCGTAGCC TGACACTCCA TGGGAACCCC 
ATGGAGGAAG AGAAAGGGTA TAGGCAATAT GTGCTGTGCA CCCTGTCCCG TATCACCACG 
TTCGACTTCA GTGGGGTCAC CAAAGCAGAC CGCACCACAG CTGAAGTCTG GAAACGCATG 
AACATCAAGC CCAAGAAGGC CTGGACCAAG CAGAATACAC TTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001192067.1
CDS	93..617
Translation	MVEFQPSVTDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Target ORF information:

RefSeq Version	NM_001205138.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001205138.4

ORF Insert Sequence:

ATGGTGGAGT TTCAGCCATC AGTGACAGAT CTGGTAAATG AGGAGCCAAG GACAGGACTA 
CGACCACTGA AGCGTTCAAA GTCGGGGAAA TCACTGACCC AGTCCCTGTG GCTGAATAAC 
AATGTTCTCA ATGATCTGAG AGACTTCAAC CAGGTGGCTT CACAGCTGTT GGAGCACCCA 
GAGAACCTGG CCTGGATCGA CCTGTCCTTT AATGACCTGA CTTCCATTGA CCCTGTCCTA 
ACAACTTTCT TCAACCTGAG TGTCCTCTAT CTTCACGGCA ACAGCATCCA GCGCCTGGGG 
GAGGTGAATA AGCTGGCTGT CCTTCCTCGG CTCCGTAGCC TGACACTCCA TGGGAACCCC 
ATGGAGGAAG AGAAAGGGTA TAGGCAATAT GTGCTGTGCA CCCTGTCCCG TATCACCACG 
TTCGACTTCA GTGGGGTCAC CAAAGCAGAC CGCACCACAG CTGAAGTCTG GAAACGCATG 
AACATCAAGC CCAAGAAGGC CTGGACCAAG CAGAATACAC TTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_024448401.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024304169.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X5, mRNA.

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CloneID	OHu77952
Clone ID Related Accession (Same CDS sequence)	XM_024448401.1
Accession Version	XM_024448401.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1101bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane O-methyltransferase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 21% of CDS bases ##RefSeq-Attributes-END##

ATGGCCGGGG TCGGGCCGGG CGCTCAGGCC GCGCCGAGGA GGGACGGCGT CCGTGAGGAG 
CCCTTCCGGT CACATGACCC GCGGCGGCCT CCCGCAGGCA ACCACCCGCC CCCACCCCCC 
GTACCCCCTG TCCCGGAGCC GCTTGGCCGC CTCAGTCAAT ACCCCGGCTT CCGGTCCCGC 
CCGCTAGCGC GTGATCGTTG TCAACCAATG GGAAGGCGAA AGCCATTCCA GCCTCCTACC 
TCAGGGTTAT CCCCCGCAGC AGGCCCTGGA CTCCCCGACC TGTCCTGTGC TCTGGTCCTC 
CAGCCCAGGG CCCAGGTAGG GACCATGTCC CCTGCCATTG CATTGGCCTT CCTGCCACTG 
GTGGTAACAT TGCTGGTGCG GTACCGGCAC TACTTCCGAT TGCTGGTGCG CACGGTCTTG 
CTGCGAAGCC TCCGAGACTG CCTGTCAGGG CTGCGGATCG AGGAGCGGGC CTTCAGCTAC 
GTGCTCACCC ATGCCCTGCC CGGTGACCCT GGTCACATCC TCACCACCCT GGACCACTGG 
AGCAGCCGCT GCGAGTACTT GAGCCACATG GGGCCTGTCA AAGGTCAGAT CCTGATGCGG 
CTGGTGGAGG AGAAGGCCCC TGCTTGTGTG CTGGAATTGG GAACCTACTG TGGATACTCT 
ACCCTGCTTA TTGCCCGAGC CCTGCCCCCT GGGGGTCGCC TTCTTACTGT GGAGCGGGAC 
CCACGCACGG CAGCAGTGGC TGAAAAACTC ATCCGCCTGG CCGGCTTTGA TGAGCACATG 
GTGGAGCTCA TCGTGGGCAG CTCAGAGGAC GTGATCCCGT GCCTACGCAC CCAGTATCAG 
CTGAGTCGGG CAGACCTGGT GCTCCTGGCA CACCGGCCAC GATGTTACCT GAGGGACCTG 
CAGCTGCTGG AGGCCCATGC CCTACTGCCA GCAGGTGCCA CCGTGCTGGC TGACCATGTG 
CTCTTCCCTG GTGCACCCCG CTTCTTGCAG TATGCTAAGA GCTGTGGCCG CTACCGCTGC 
CGCCTCCACC ACACTGGCCT TCCAGACTTC CCTGCCATCA AGGATGGAAT AGCTCAGCTC 
ACCTATGCTG GACCAGGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024304169.1
CDS	1..1101
Translation	MAGVGPGAQAAPRRDGVREEPFRSHDPRRPPAGNHPPPPPVPPVPEPLGRLSQYPGFRSRPLARDRCQPMGRRKPFQPPTSGLSPAAGPGLPDLSCALVLQPRAQVGTMSPAIALAFLPLVVTLLVRYRHYFRLLVRTVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAGFDEHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATVLADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG

Target ORF information:

RefSeq Version	XM_024448401.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024448401.1

ORF Insert Sequence:

ATGGCCGGGG TCGGGCCGGG CGCTCAGGCC GCGCCGAGGA GGGACGGCGT CCGTGAGGAG 
CCCTTCCGGT CACATGACCC GCGGCGGCCT CCCGCAGGCA ACCACCCGCC CCCACCCCCC 
GTACCCCCTG TCCCGGAGCC GCTTGGCCGC CTCAGTCAAT ACCCCGGCTT CCGGTCCCGC 
CCGCTAGCGC GTGATCGTTG TCAACCAATG GGAAGGCGAA AGCCATTCCA GCCTCCTACC 
TCAGGGTTAT CCCCCGCAGC AGGCCCTGGA CTCCCCGACC TGTCCTGTGC TCTGGTCCTC 
CAGCCCAGGG CCCAGGTAGG GACCATGTCC CCTGCCATTG CATTGGCCTT CCTGCCACTG 
GTGGTAACAT TGCTGGTGCG GTACCGGCAC TACTTCCGAT TGCTGGTGCG CACGGTCTTG 
CTGCGAAGCC TCCGAGACTG CCTGTCAGGG CTGCGGATCG AGGAGCGGGC CTTCAGCTAC 
GTGCTCACCC ATGCCCTGCC CGGTGACCCT GGTCACATCC TCACCACCCT GGACCACTGG 
AGCAGCCGCT GCGAGTACTT GAGCCACATG GGGCCTGTCA AAGGTCAGAT CCTGATGCGG 
CTGGTGGAGG AGAAGGCCCC TGCTTGTGTG CTGGAATTGG GAACCTACTG TGGATACTCT 
ACCCTGCTTA TTGCCCGAGC CCTGCCCCCT GGGGGTCGCC TTCTTACTGT GGAGCGGGAC 
CCACGCACGG CAGCAGTGGC TGAAAAACTC ATCCGCCTGG CCGGCTTTGA TGAGCACATG 
GTGGAGCTCA TCGTGGGCAG CTCAGAGGAC GTGATCCCGT GCCTACGCAC CCAGTATCAG 
CTGAGTCGGG CAGACCTGGT GCTCCTGGCA CACCGGCCAC GATGTTACCT GAGGGACCTG 
CAGCTGCTGG AGGCCCATGC CCTACTGCCA GCAGGTGCCA CCGTGCTGGC TGACCATGTG 
CTCTTCCCTG GTGCACCCCG CTTCTTGCAG TATGCTAAGA GCTGTGGCCG CTACCGCTGC 
CGCCTCCACC ACACTGGCCT TCCAGACTTC CCTGCCATCA AGGATGGAAT AGCTCAGCTC 
ACCTATGCTG GACCAGGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_017017356.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016872845.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu92035
Clone ID Related Accession (Same CDS sequence)	XM_017017356.1 , XM_017017357.1 , XM_017017358.1
Accession Version	XM_017017356.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	transmembrane O-methyltransferase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCCTG CCATTGCATT GGCCTTCCTG CCACTGGTGG TAACATTGCT GGTGCGGTAC 
CGGCACTACT TCCGATTGCT GGTGCGCACG GTCTTGCTGC GAAGCCTCCG AGACTGCCTG 
TCAGGGCTGC GGATCGAGGA GCGGGCCTTC AGCTACGTGC TCACCCATGC CCTGCCCGGT 
GACCCTGGTC ACATCCTCAC CACCCTGGAC CACTGGAGCA GCCGCTGCGA GTACTTGAGC 
CACATGGGGC CTGTCAAAGG TCAGATCCTG ATGCGGCTGG TGGAGGAGAA GGCCCCTGCT 
TGTGTGCTGG AATTGGGAAC CTACTGTGGA TACTCTACCC TGCTTATTGC CCGAGCCCTG 
CCCCCTGGGG GTCGCCTTCT TACTGTGGAG CGGGACCCAC GCACGGCAGC AGTGGCTGAA 
AAACTCATCC GCCTGGCCGG CTTTGATGAG CACATGGTGG AGCTCATCGT GGGCAGCTCA 
GAGGACGTGA TCCCGTGCCT ACGCACCCAG TATCAGCTGA GTCGGGCAGA CCTGGTGCTC 
CTGGCACACC GGCCACGATG TTACCTGAGG GACCTGCAGC TGCTGGAGGC CCATGCCCTA 
CTGCCAGCAG GTGCCACCGT GCTGGCTGAC CATGTGCTCT TCCCTGGTGC ACCCCGCTTC 
TTGCAGTATG CTAAGAGCTG TGGCCGCTAC CGCTGCCGCC TCCACCACAC TGGCCTTCCA 
GACTTCCCTG CCATCAAGGA TGGAATAGCT CAGCTCACCT ATGCTGGACC AGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016872845.1
CDS	1591..2367
Translation	MSPAIALAFLPLVVTLLVRYRHYFRLLVRTVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAGFDEHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATVLADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG

Target ORF information:

RefSeq Version	XM_017017356.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017356.1

ORF Insert Sequence:

ATGTCCCCTG CCATTGCATT GGCCTTCCTG CCACTGGTGG TAACATTGCT GGTGCGGTAC 
CGGCACTACT TCCGATTGCT GGTGCGCACG GTCTTGCTGC GAAGCCTCCG AGACTGCCTG 
TCAGGGCTGC GGATCGAGGA GCGGGCCTTC AGCTACGTGC TCACCCATGC CCTGCCCGGT 
GACCCTGGTC ACATCCTCAC CACCCTGGAC CACTGGAGCA GCCGCTGCGA GTACTTGAGC 
CACATGGGGC CTGTCAAAGG TCAGATCCTG ATGCGGCTGG TGGAGGAGAA GGCCCCTGCT 
TGTGTGCTGG AATTGGGAAC CTACTGTGGA TACTCTACCC TGCTTATTGC CCGAGCCCTG 
CCCCCTGGGG GTCGCCTTCT TACTGTGGAG CGGGACCCAC GCACGGCAGC AGTGGCTGAA 
AAACTCATCC GCCTGGCCGG CTTTGATGAG CACATGGTGG AGCTCATCGT GGGCAGCTCA 
GAGGACGTGA TCCCGTGCCT ACGCACCCAG TATCAGCTGA GTCGGGCAGA CCTGGTGCTC 
CTGGCACACC GGCCACGATG TTACCTGAGG GACCTGCAGC TGCTGGAGGC CCATGCCCTA 
CTGCCAGCAG GTGCCACCGT GCTGGCTGAC CATGTGCTCT TCCCTGGTGC ACCCCGCTTC 
TTGCAGTATG CTAAGAGCTG TGGCCGCTAC CGCTGCCGCC TCCACCACAC TGGCCTTCCA 
GACTTCCCTG CCATCAAGGA TGGAATAGCT CAGCTCACCT ATGCTGGACC AGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_017017357.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016872846.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu92035
Clone ID Related Accession (Same CDS sequence)	XM_017017356.1 , XM_017017357.1 , XM_017017358.1
Accession Version	XM_017017357.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	transmembrane O-methyltransferase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCCTG CCATTGCATT GGCCTTCCTG CCACTGGTGG TAACATTGCT GGTGCGGTAC 
CGGCACTACT TCCGATTGCT GGTGCGCACG GTCTTGCTGC GAAGCCTCCG AGACTGCCTG 
TCAGGGCTGC GGATCGAGGA GCGGGCCTTC AGCTACGTGC TCACCCATGC CCTGCCCGGT 
GACCCTGGTC ACATCCTCAC CACCCTGGAC CACTGGAGCA GCCGCTGCGA GTACTTGAGC 
CACATGGGGC CTGTCAAAGG TCAGATCCTG ATGCGGCTGG TGGAGGAGAA GGCCCCTGCT 
TGTGTGCTGG AATTGGGAAC CTACTGTGGA TACTCTACCC TGCTTATTGC CCGAGCCCTG 
CCCCCTGGGG GTCGCCTTCT TACTGTGGAG CGGGACCCAC GCACGGCAGC AGTGGCTGAA 
AAACTCATCC GCCTGGCCGG CTTTGATGAG CACATGGTGG AGCTCATCGT GGGCAGCTCA 
GAGGACGTGA TCCCGTGCCT ACGCACCCAG TATCAGCTGA GTCGGGCAGA CCTGGTGCTC 
CTGGCACACC GGCCACGATG TTACCTGAGG GACCTGCAGC TGCTGGAGGC CCATGCCCTA 
CTGCCAGCAG GTGCCACCGT GCTGGCTGAC CATGTGCTCT TCCCTGGTGC ACCCCGCTTC 
TTGCAGTATG CTAAGAGCTG TGGCCGCTAC CGCTGCCGCC TCCACCACAC TGGCCTTCCA 
GACTTCCCTG CCATCAAGGA TGGAATAGCT CAGCTCACCT ATGCTGGACC AGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016872846.1
CDS	2514..3290
Translation	MSPAIALAFLPLVVTLLVRYRHYFRLLVRTVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAGFDEHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATVLADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG

Target ORF information:

RefSeq Version	XM_017017357.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017357.1

ORF Insert Sequence:

ATGTCCCCTG CCATTGCATT GGCCTTCCTG CCACTGGTGG TAACATTGCT GGTGCGGTAC 
CGGCACTACT TCCGATTGCT GGTGCGCACG GTCTTGCTGC GAAGCCTCCG AGACTGCCTG 
TCAGGGCTGC GGATCGAGGA GCGGGCCTTC AGCTACGTGC TCACCCATGC CCTGCCCGGT 
GACCCTGGTC ACATCCTCAC CACCCTGGAC CACTGGAGCA GCCGCTGCGA GTACTTGAGC 
CACATGGGGC CTGTCAAAGG TCAGATCCTG ATGCGGCTGG TGGAGGAGAA GGCCCCTGCT 
TGTGTGCTGG AATTGGGAAC CTACTGTGGA TACTCTACCC TGCTTATTGC CCGAGCCCTG 
CCCCCTGGGG GTCGCCTTCT TACTGTGGAG CGGGACCCAC GCACGGCAGC AGTGGCTGAA 
AAACTCATCC GCCTGGCCGG CTTTGATGAG CACATGGTGG AGCTCATCGT GGGCAGCTCA 
GAGGACGTGA TCCCGTGCCT ACGCACCCAG TATCAGCTGA GTCGGGCAGA CCTGGTGCTC 
CTGGCACACC GGCCACGATG TTACCTGAGG GACCTGCAGC TGCTGGAGGC CCATGCCCTA 
CTGCCAGCAG GTGCCACCGT GCTGGCTGAC CATGTGCTCT TCCCTGGTGC ACCCCGCTTC 
TTGCAGTATG CTAAGAGCTG TGGCCGCTAC CGCTGCCGCC TCCACCACAC TGGCCTTCCA 
GACTTCCCTG CCATCAAGGA TGGAATAGCT CAGCTCACCT ATGCTGGACC AGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRTOMT ( XM_017017358.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016872847.1 Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X3, mRNA.

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CloneID	OHu92035
Clone ID Related Accession (Same CDS sequence)	XM_017017356.1 , XM_017017357.1 , XM_017017358.1
Accession Version	XM_017017358.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	transmembrane O-methyltransferase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCCTG CCATTGCATT GGCCTTCCTG CCACTGGTGG TAACATTGCT GGTGCGGTAC 
CGGCACTACT TCCGATTGCT GGTGCGCACG GTCTTGCTGC GAAGCCTCCG AGACTGCCTG 
TCAGGGCTGC GGATCGAGGA GCGGGCCTTC AGCTACGTGC TCACCCATGC CCTGCCCGGT 
GACCCTGGTC ACATCCTCAC CACCCTGGAC CACTGGAGCA GCCGCTGCGA GTACTTGAGC 
CACATGGGGC CTGTCAAAGG TCAGATCCTG ATGCGGCTGG TGGAGGAGAA GGCCCCTGCT 
TGTGTGCTGG AATTGGGAAC CTACTGTGGA TACTCTACCC TGCTTATTGC CCGAGCCCTG 
CCCCCTGGGG GTCGCCTTCT TACTGTGGAG CGGGACCCAC GCACGGCAGC AGTGGCTGAA 
AAACTCATCC GCCTGGCCGG CTTTGATGAG CACATGGTGG AGCTCATCGT GGGCAGCTCA 
GAGGACGTGA TCCCGTGCCT ACGCACCCAG TATCAGCTGA GTCGGGCAGA CCTGGTGCTC 
CTGGCACACC GGCCACGATG TTACCTGAGG GACCTGCAGC TGCTGGAGGC CCATGCCCTA 
CTGCCAGCAG GTGCCACCGT GCTGGCTGAC CATGTGCTCT TCCCTGGTGC ACCCCGCTTC 
TTGCAGTATG CTAAGAGCTG TGGCCGCTAC CGCTGCCGCC TCCACCACAC TGGCCTTCCA 
GACTTCCCTG CCATCAAGGA TGGAATAGCT CAGCTCACCT ATGCTGGACC AGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016872847.1
CDS	2514..3290
Translation	MSPAIALAFLPLVVTLLVRYRHYFRLLVRTVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAGFDEHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATVLADHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG

Target ORF information:

RefSeq Version	XM_017017358.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017017358.1

ORF Insert Sequence:

ATGTCCCCTG CCATTGCATT GGCCTTCCTG CCACTGGTGG TAACATTGCT GGTGCGGTAC 
CGGCACTACT TCCGATTGCT GGTGCGCACG GTCTTGCTGC GAAGCCTCCG AGACTGCCTG 
TCAGGGCTGC GGATCGAGGA GCGGGCCTTC AGCTACGTGC TCACCCATGC CCTGCCCGGT 
GACCCTGGTC ACATCCTCAC CACCCTGGAC CACTGGAGCA GCCGCTGCGA GTACTTGAGC 
CACATGGGGC CTGTCAAAGG TCAGATCCTG ATGCGGCTGG TGGAGGAGAA GGCCCCTGCT 
TGTGTGCTGG AATTGGGAAC CTACTGTGGA TACTCTACCC TGCTTATTGC CCGAGCCCTG 
CCCCCTGGGG GTCGCCTTCT TACTGTGGAG CGGGACCCAC GCACGGCAGC AGTGGCTGAA 
AAACTCATCC GCCTGGCCGG CTTTGATGAG CACATGGTGG AGCTCATCGT GGGCAGCTCA 
GAGGACGTGA TCCCGTGCCT ACGCACCCAG TATCAGCTGA GTCGGGCAGA CCTGGTGCTC 
CTGGCACACC GGCCACGATG TTACCTGAGG GACCTGCAGC TGCTGGAGGC CCATGCCCTA 
CTGCCAGCAG GTGCCACCGT GCTGGCTGAC CATGTGCTCT TCCCTGGTGC ACCCCGCTTC 
TTGCAGTATG CTAAGAGCTG TGGCCGCTAC CGCTGCCGCC TCCACCACAC TGGCCTTCCA 
GACTTCCCTG CCATCAAGGA TGGAATAGCT CAGCTCACCT ATGCTGGACC AGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Novel mutations in LRTOMT associated with moderate progressive hearing loss in autosomal recessive inheritance.
The Annals of otology, rhinology, and laryngology124 Suppl 1142S-7S(2015 May)
Ichinose A,Moteki H,Hattori M,Nishio SY,Usami S

The c.242G>A mutation in LRTOMT gene is responsible for a high prevalence of deafness in the Moroccan population.
Molecular biology reports39(12)11011-6(2012 Dec)
Charif M,Bounaceur S,Abidi O,Nahili H,Rouba H,Kandil M,Boulouiz R,Barakat A

A 1 bp deletion in the dual reading frame deafness gene LRTOMT causes a frameshift from the first into the second reading frame.
American journal of medical genetics. Part A155A(8)2021-3(2011 Aug)
Vanwesemael M,Schrauwen I,Ceuppens R,Alasti F,Jorssen E,Farrokhi E,Chaleshtori MH,Van Camp G

Mutations of LRTOMT, a fusion gene with alternative reading frames, cause nonsyndromic deafness in humans.
Nature genetics40(11)1335-40(2008 Nov)
Ahmed ZM,Masmoudi S,Kalay E,Belyantseva IA,Mosrati MA,Collin RW,Riazuddin S,Hmani-Aifa M,Venselaar H,Kawar MN,Tlili A,van der Zwaag B,Khan SY,Ayadi L,Riazuddin SA,Morell RJ,Griffith AJ,Charfedine I,Caylan R,Oostrik J,Karaguzel A,Ghorbel A,Riazuddin S,Friedman TB,Ayadi H,Kremer H

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LRTOMT cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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