CCN2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCN2
Entrez Gene ID	1490
Full Name	connective tissue growth factor
Synonyms	CCN2,HCS24,IGFBP8,NOV2
General protein information	Preferred Names connective tissue growth factor Names connective tissue growth factor CCN family member 2 IBP-8 IGF-binding protein 8 IGFBP-8 hypertrophic chondrocyte-specific protein 24 insulin-like growth factor-binding protein 8
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q23.2
Summary	The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009].
Disorder MIM:	121009

mRNA and Protein(s)

mRNA	Protein	Name
NM_001901.2	NP_001892.1	connective tissue growth factor precursor
NM_001901.3	NP_001892.1	CCN family member 2 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CTGF	XP_518744.2
Canis lupus familiaris (dog)	LOC476202	XP_003638817.1
Mus musculus (house mouse)	Ctgf	NP_034347.2
Gallus gallus (chicken)	CTGF	NP_989605.1
Xenopus tropicalis (tropical clawed frog)	ctgf	NP_001015042.1
Rattus norvegicus (Norway rat)	Ctgf	NP_071602.1
Homo sapiens (human)	CTGF	NP_001892.1
Bos taurus (cattle)	CTGF	NP_776455.1
Danio rerio (zebrafish)	ctgfa	NP_001015041.1

Gene Ontology

The following CCN2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCN2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25598	NM_001901.3 Latest version!	Homo sapiens cellular communication network factor 2 (CCN2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu25598	NM_001901.2	Homo sapiens connective tissue growth factor (CTGF), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCN2 ( NM_001901.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001892.1 Homo sapiens connective tissue growth factor (CTGF), mRNA.

Price & Availability↑

CloneID	OHu25598
Clone ID Related Accession (Same CDS sequence)	NM_001901.2 , NM_001901.3
Accession Version	NM_001901.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1050bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-31
Organism	Homo sapiens(human)
Product	connective tissue growth factor precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA552292.1 and BC087839.1. This sequence is a reference standard in the RefSeqGene project. On May 19, 2006 this sequence version replaced NM_001901.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC087839.1, ERR279834.96.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2159080, SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCGCCG CCAGTATGGG CCCCGTCCGC GTCGCCTTCG TGGTCCTCCT CGCCCTCTGC 
AGCCGGCCGG CCGTCGGCCA GAACTGCAGC GGGCCGTGCC GGTGCCCGGA CGAGCCGGCG 
CCGCGCTGCC CGGCGGGCGT GAGCCTCGTG CTGGACGGCT GCGGCTGCTG CCGCGTCTGC 
GCCAAGCAGC TGGGCGAGCT GTGCACCGAG CGCGACCCCT GCGACCCGCA CAAGGGCCTC 
TTCTGTGACT TCGGCTCCCC GGCCAACCGC AAGATCGGCG TGTGCACCGC CAAAGATGGT 
GCTCCCTGCA TCTTCGGTGG TACGGTGTAC CGCAGCGGAG AGTCCTTCCA GAGCAGCTGC 
AAGTACCAGT GCACGTGCCT GGACGGGGCG GTGGGCTGCA TGCCCCTGTG CAGCATGGAC 
GTTCGTCTGC CCAGCCCTGA CTGCCCCTTC CCGAGGAGGG TCAAGCTGCC CGGGAAATGC 
TGCGAGGAGT GGGTGTGTGA CGAGCCCAAG GACCAAACCG TGGTTGGGCC TGCCCTCGCG 
GCTTACCGAC TGGAAGACAC GTTTGGCCCA GACCCAACTA TGATTAGAGC CAACTGCCTG 
GTCCAGACCA CAGAGTGGAG CGCCTGTTCC AAGACCTGTG GGATGGGCAT CTCCACCCGG 
GTTACCAATG ACAACGCCTC CTGCAGGCTA GAGAAGCAGA GCCGCCTGTG CATGGTCAGG 
CCTTGCGAAG CTGACCTGGA AGAGAACATT AAGAAGGGCA AAAAGTGCAT CCGTACTCCC 
AAAATCTCCA AGCCTATCAA GTTTGAGCTT TCTGGCTGCA CCAGCATGAA GACATACCGA 
GCTAAATTCT GTGGAGTATG TACCGACGGC CGATGCTGCA CCCCCCACAG AACCACCACC 
CTGCCGGTGG AGTTCAAGTG CCCTGACGGC GAGGTCATGA AGAAGAACAT GATGTTCATC 
AAGACCTGTG CCTGCCATTA CAACTGTCCC GGAGACAATG ACATCTTTGA ATCGCTGTAC 
TACAGGAAGA TGTACGGAGA CATGGCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001892.1
CDS	207..1256
Translation	MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA

Target ORF information:

RefSeq Version	NM_001901.2
Organism	Homo sapiens(human)
Definition	Homo sapiens connective tissue growth factor (CTGF), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001901.2

ORF Insert Sequence:

ATGACCGCCG CCAGTATGGG CCCCGTCCGC GTCGCCTTCG TGGTCCTCCT CGCCCTCTGC 
AGCCGGCCGG CCGTCGGCCA GAACTGCAGC GGGCCGTGCC GGTGCCCGGA CGAGCCGGCG 
CCGCGCTGCC CGGCGGGCGT GAGCCTCGTG CTGGACGGCT GCGGCTGCTG CCGCGTCTGC 
GCCAAGCAGC TGGGCGAGCT GTGCACCGAG CGCGACCCCT GCGACCCGCA CAAGGGCCTC 
TTCTGTGACT TCGGCTCCCC GGCCAACCGC AAGATCGGCG TGTGCACCGC CAAAGATGGT 
GCTCCCTGCA TCTTCGGTGG TACGGTGTAC CGCAGCGGAG AGTCCTTCCA GAGCAGCTGC 
AAGTACCAGT GCACGTGCCT GGACGGGGCG GTGGGCTGCA TGCCCCTGTG CAGCATGGAC 
GTTCGTCTGC CCAGCCCTGA CTGCCCCTTC CCGAGGAGGG TCAAGCTGCC CGGGAAATGC 
TGCGAGGAGT GGGTGTGTGA CGAGCCCAAG GACCAAACCG TGGTTGGGCC TGCCCTCGCG 
GCTTACCGAC TGGAAGACAC GTTTGGCCCA GACCCAACTA TGATTAGAGC CAACTGCCTG 
GTCCAGACCA CAGAGTGGAG CGCCTGTTCC AAGACCTGTG GGATGGGCAT CTCCACCCGG 
GTTACCAATG ACAACGCCTC CTGCAGGCTA GAGAAGCAGA GCCGCCTGTG CATGGTCAGG 
CCTTGCGAAG CTGACCTGGA AGAGAACATT AAGAAGGGCA AAAAGTGCAT CCGTACTCCC 
AAAATCTCCA AGCCTATCAA GTTTGAGCTT TCTGGCTGCA CCAGCATGAA GACATACCGA 
GCTAAATTCT GTGGAGTATG TACCGACGGC CGATGCTGCA CCCCCCACAG AACCACCACC 
CTGCCGGTGG AGTTCAAGTG CCCTGACGGC GAGGTCATGA AGAAGAACAT GATGTTCATC 
AAGACCTGTG CCTGCCATTA CAACTGTCCC GGAGACAATG ACATCTTTGA ATCGCTGTAC 
TACAGGAAGA TGTACGGAGA CATGGCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCN2 ( NM_001901.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001892.1 Homo sapiens cellular communication network factor 2 (CCN2), mRNA.

Price & Availability↑

CloneID	OHu25598
Clone ID Related Accession (Same CDS sequence)	NM_001901.2 , NM_001901.3
Accession Version	NM_001901.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1050bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	CCN family member 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA552292.1 and BC087839.1. On Nov 22, 2018 this sequence version replaced NM_001901.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC087839.1, AK290884.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACCGCCG CCAGTATGGG CCCCGTCCGC GTCGCCTTCG TGGTCCTCCT CGCCCTCTGC 
AGCCGGCCGG CCGTCGGCCA GAACTGCAGC GGGCCGTGCC GGTGCCCGGA CGAGCCGGCG 
CCGCGCTGCC CGGCGGGCGT GAGCCTCGTG CTGGACGGCT GCGGCTGCTG CCGCGTCTGC 
GCCAAGCAGC TGGGCGAGCT GTGCACCGAG CGCGACCCCT GCGACCCGCA CAAGGGCCTC 
TTCTGTGACT TCGGCTCCCC GGCCAACCGC AAGATCGGCG TGTGCACCGC CAAAGATGGT 
GCTCCCTGCA TCTTCGGTGG TACGGTGTAC CGCAGCGGAG AGTCCTTCCA GAGCAGCTGC 
AAGTACCAGT GCACGTGCCT GGACGGGGCG GTGGGCTGCA TGCCCCTGTG CAGCATGGAC 
GTTCGTCTGC CCAGCCCTGA CTGCCCCTTC CCGAGGAGGG TCAAGCTGCC CGGGAAATGC 
TGCGAGGAGT GGGTGTGTGA CGAGCCCAAG GACCAAACCG TGGTTGGGCC TGCCCTCGCG 
GCTTACCGAC TGGAAGACAC GTTTGGCCCA GACCCAACTA TGATTAGAGC CAACTGCCTG 
GTCCAGACCA CAGAGTGGAG CGCCTGTTCC AAGACCTGTG GGATGGGCAT CTCCACCCGG 
GTTACCAATG ACAACGCCTC CTGCAGGCTA GAGAAGCAGA GCCGCCTGTG CATGGTCAGG 
CCTTGCGAAG CTGACCTGGA AGAGAACATT AAGAAGGGCA AAAAGTGCAT CCGTACTCCC 
AAAATCTCCA AGCCTATCAA GTTTGAGCTT TCTGGCTGCA CCAGCATGAA GACATACCGA 
GCTAAATTCT GTGGAGTATG TACCGACGGC CGATGCTGCA CCCCCCACAG AACCACCACC 
CTGCCGGTGG AGTTCAAGTG CCCTGACGGC GAGGTCATGA AGAAGAACAT GATGTTCATC 
AAGACCTGTG CCTGCCATTA CAACTGTCCC GGAGACAATG ACATCTTTGA ATCGCTGTAC 
TACAGGAAGA TGTACGGAGA CATGGCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001892.1
CDS	201..1250
Translation	MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA

Target ORF information:

RefSeq Version	NM_001901.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cellular communication network factor 2 (CCN2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001901.3

ORF Insert Sequence:

ATGACCGCCG CCAGTATGGG CCCCGTCCGC GTCGCCTTCG TGGTCCTCCT CGCCCTCTGC 
AGCCGGCCGG CCGTCGGCCA GAACTGCAGC GGGCCGTGCC GGTGCCCGGA CGAGCCGGCG 
CCGCGCTGCC CGGCGGGCGT GAGCCTCGTG CTGGACGGCT GCGGCTGCTG CCGCGTCTGC 
GCCAAGCAGC TGGGCGAGCT GTGCACCGAG CGCGACCCCT GCGACCCGCA CAAGGGCCTC 
TTCTGTGACT TCGGCTCCCC GGCCAACCGC AAGATCGGCG TGTGCACCGC CAAAGATGGT 
GCTCCCTGCA TCTTCGGTGG TACGGTGTAC CGCAGCGGAG AGTCCTTCCA GAGCAGCTGC 
AAGTACCAGT GCACGTGCCT GGACGGGGCG GTGGGCTGCA TGCCCCTGTG CAGCATGGAC 
GTTCGTCTGC CCAGCCCTGA CTGCCCCTTC CCGAGGAGGG TCAAGCTGCC CGGGAAATGC 
TGCGAGGAGT GGGTGTGTGA CGAGCCCAAG GACCAAACCG TGGTTGGGCC TGCCCTCGCG 
GCTTACCGAC TGGAAGACAC GTTTGGCCCA GACCCAACTA TGATTAGAGC CAACTGCCTG 
GTCCAGACCA CAGAGTGGAG CGCCTGTTCC AAGACCTGTG GGATGGGCAT CTCCACCCGG 
GTTACCAATG ACAACGCCTC CTGCAGGCTA GAGAAGCAGA GCCGCCTGTG CATGGTCAGG 
CCTTGCGAAG CTGACCTGGA AGAGAACATT AAGAAGGGCA AAAAGTGCAT CCGTACTCCC 
AAAATCTCCA AGCCTATCAA GTTTGAGCTT TCTGGCTGCA CCAGCATGAA GACATACCGA 
GCTAAATTCT GTGGAGTATG TACCGACGGC CGATGCTGCA CCCCCCACAG AACCACCACC 
CTGCCGGTGG AGTTCAAGTG CCCTGACGGC GAGGTCATGA AGAAGAACAT GATGTTCATC 
AAGACCTGTG CCTGCCATTA CAACTGTCCC GGAGACAATG ACATCTTTGA ATCGCTGTAC 
TACAGGAAGA TGTACGGAGA CATGGCATGA