PRDM4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PRDM4
Entrez Gene ID	11108
Full Name	PR/SET domain 4
Synonyms	PFM1
General protein information	Preferred Names PR/SET domain 4 Names PR domain zinc finger protein 4 PR domain 4 PR domain containing 4 PR domain-containing protein 4 PR-domain zinc-finger protein PFM1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q23.3
Summary	The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes. [provided by RefSeq, Jul 2008].
Disorder MIM:	605780

mRNA and Protein(s)

mRNA	Protein	Name
NM_012406.3	NP_036538.3	PR domain zinc finger protein 4
XM_005268593.1	XP_005268650.1	PR domain zinc finger protein 4 isoform X1
XM_024448807.1	XP_024304575.1	PR domain zinc finger protein 4 isoform X1
NM_012406.4	NP_036538.3	PR domain zinc finger protein 4

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Prdm4	NP_579846.1
Danio rerio (zebrafish)	prdm4	NP_001116215.1
Pan troglodytes (chimpanzee)	PRDM4	XP_001162965.1
	PRDM4	XP_001101382.1
Canis lupus familiaris (dog)	PRDM4	XP_538412.2
Bos taurus (cattle)	PRDM4	XP_005206854.1
Xenopus tropicalis (tropical clawed frog)	prdm4	NP_001072257.1
Homo sapiens (human)	PRDM4	NP_036538.3
Mus musculus (house mouse)	Prdm4	NP_857633.2
Gallus gallus (chicken)	PRDM4	XP_416301.4

Gene Ontology
Bibliography

Related articles in PubMed

Identification of Prdm genes in human corneal endothelium.
Rolev K, O'Donovan DG, Georgiou C, Rajan MS, Chittka A
Experimental eye research159114-122(2017 06)

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
Navarini AA, Simpson MA, Weale M, Knight J, Carlavan I, Reiniche P, Burden DA, Layton A, Bataille V, Allen M, Pleass R, Pink A, Creamer D, English J, Munn S, Walton S, , Willis C, D?ret S, Voegel JJ, Spector T, Smith CH, Trembath RC, Barker JN
Nature communications54020(2014 Jun)

Transcription factor positive regulatory domain 4 (PRDM4) recruits protein arginine methyltransferase 5 (PRMT5) to mediate histone arginine methylation and control neural stem cell proliferation and differentiation.
Chittka A, Nitarska J, Grazini U, Richardson WD
The Journal of biological chemistry287(51)42995-3006(2012 Dec)

The PR/SET domain in PRDM4 is preceded by a zinc knuckle.
Briknarov? K, Atwater DZ, Glicken JM, Maynard SJ, Ness TE
Proteins79(7)2341-5(2011 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Both Prdm 4 and Prdm 5 are expressed in human corneal endothelium, primary hCECs and in HCECs-12 cells, characterised by expression of the Na(+)/K(+)-ATPase.
Title: Identification of Prdm genes in human corneal endothelium.

PRDM4 zinc knuckle by NMR spectroscopy.
Title: The PR/SET domain in PRDM4 is preceded by a zinc knuckle.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following PRDM4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PRDM4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06214	NM_012406.4 Latest version!	Homo sapiens PR/SET domain 4 (PRDM4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu46269	XM_005268593.1 Latest version!	Homo sapiens PR/SET domain 4 (PRDM4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu46269	XM_024448807.1 Latest version!	Homo sapiens PR/SET domain 4 (PRDM4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu06214	NM_012406.3	Homo sapiens PR/SET domain 4 (PRDM4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PRDM4 ( NM_012406.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036538.3 Homo sapiens PR/SET domain 4 (PRDM4), mRNA.

Price & Availability↑

CloneID	OHu06214
Clone ID Related Accession (Same CDS sequence)	NM_012406.3 , NM_012406.4
Accession Version	NM_012406.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2406bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	PR domain zinc finger protein 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU502236.1, AK056378.1, AL133083.1, BC035581.1 and AF144757.2. On Jan 26, 2004 this sequence version replaced NM_012406.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.39635.1, SRR1660807.82133.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCATCACA GGATGAATGA AATGAACCTG AGTCCAGTGG GGATGGAGCA GCTGACTTCA 
TCCTCTGTGA GCAATGCCTT GCCAGTCTCA GGAAGTCACC TGGGATTGGC TGCCTCACCC 
ACTCACAGTG CCATCCCTGC CCCAGGCCTC CCAGTGGCAA TTCCAAACCT GGGTCCCTCC 
CTGAGCTCTC TGCCTTCTGC TCTGTCTTTA ATGCTACCAA TGGGTATTGG GGATCGAGGG 
GTGATGTGTG GGTTACCTGA AAGAAACTAC ACCCTACCTC CACCACCTTA CCCTCACCTG 
GAGAGCAGTT ATTTCAGAAC CATTCTACCT GGCATTTTAT CTTATTTAGC TGACAGACCA 
CCTCCACAGT ACATCCACCC TAACTCTATA AATGTTGATG GTAATACAGC ATTATCTATC 
ACCAATAACC CTTCAGCACT AGATCCCTAT CAGTCCAATG GAAATGTTGG ATTAGAACCA 
GGCATTGTTT CAATAGACTC TCGCTCTGTG AACACACATG GTGCCCAAAG TCTTCATCCC 
AGTGATGGCC ATGAGGTGGC CTTGGACACA GCAATCACTA TGGAGAACGT TTCTAGGGTT 
ACCAGCCCAA TTTCGACAGA TGGAATGGCA GAGGAGCTTA CGATGGACGG TGTTGCAGGC 
GAGCATTCCC AAATCCCAAA TGGCTCCAGA AGTCATGAAC CTCTGTCTGT GGATTCTGTG 
AGCAACAACC TTGCAGCAGA CGCTGTAGGA CATGGTGGTG TGATACCCAT GCATGGGAAT 
GGCCTGGAGC TCCCTGTGGT CATGGAGACA GACCACATTG CAAGTCGGGT CAATGGCATG 
TCTGACAGTG CCCTCAGTGA CTCCATTCAC ACTGTGGCCA TGAGCACCAA CTCTGTAAGC 
GTGGCACTCT CTACCTCACA CAACCTTGCC TCCCTAGAAT CTGTTTCCCT CCATGAAGTT 
GGCCTCAGCC TAGAACCTGT GGCTGTCTCC TCCATCACCC AGGAGGTTGC TATGGGGACA 
GGTCATGTAG ATGTATCTTC AGACAGTCTT TCTTTTGTAT CACCTTCACT GCAAATGGAA 
GACTCCAATT CAAACAAGGA GAACATGGCA ACCTTGTTTA CAATTTGGTG TACTCTGTGT 
GACCGCGCCT ATCCCTCGGA CTGTCCCGAA CATGGACCAG TGACTTTTGT TCCTGACACT 
CCAATAGAGA GCAGAGCAAG GCTTTCTCTC CCAAAGCAGC TTGTTCTCCG TCAGTCAATT 
GTGGGAGCAG AAGTTGGTGT ATGGACTGGA GAAACCATTC CTGTGCGGAC TTGCTTTGGA 
CCTCTAATTG GCCAGCAGAG TCACTCCATG GAAGTAGCAG AATGGACAGA CAAGGCAGTT 
AACCATATCT GGAAGATATA CCACAATGGT GTCCTAGAAT TCTGCATCAT TACAACTGAT 
GAAAATGAAT GTAATTGGAT GATGTTTGTG CGCAAAGCCA GGAACCGGGA AGAGCAGAAT 
TTGGTGGCTT ATCCTCATGA TGGAAAAATC TTTTTCTGCA CCTCACAAGA TATCCCTCCT 
GAAAATGAAC TGCTTTTTTA TTATAGCCGA GATTATGCTC AACAGATTGG TGTTCCTGAA 
CACCCAGATG TGCATCTCTG TAACTGTGGC AAGGAGTGCA ATTCTTACAC AGAGTTCAAA 
GCCCATCTGA CCAGCCACAT CCATAACCAT CTTCCTACCC AGGGACATAG CGGCAGCCAT 
GGGCCAAGTC ACAGCAAAGA AAGGAAGTGG AAGTGCTCAA TGTGCCCCCA AGCTTTTATC 
TCTCCTTCCA AACTTCATGT CCACTTTATG GGTCACATGG GTATGAAGCC CCACAAGTGT 
GATTTCTGTA GCAAGGCTTT TAGTGATCCC AGCAACCTGC GGACCCACCT CAAGATACAT 
ACAGGTCAGA AGAACTACAG GTGTACCTTG TGTGACAAGT CTTTCACCCA GAAGGCTCAC 
CTGGAGTCCC ACATGGTTAT CCACACTGGG GAGAAGAATC TTAAGTGTGA TTACTGTGAC 
AAGTTGTTTA TGCGGAGGCA GGACCTCAAG CAGCACGTGC TCATCCACAC TCAAGAACGC 
CAGATCAAGT GTCCCAAGTG TGATAAGCTG TTCTTGAGAA CAAATCACTT AAAGAAGCAT 
CTCAATTCTC ATGAAGGAAA ACGGGATTAT GTCTGTGAAA AATGTACAAA GGCTTATCTA 
ACCAAATACC ATCTCACCCG CCACCTGAAA ACCTGCAAAG GGCCCACCTC CAGTTCGTCA 
GCACCAGAGG AGGAAGAAGA GGATGACTCA GAAGAGGAAG ATCTAGCAGA CTCTGTGGGG 
ACAGAAGACT GTAGGATTAA CAGTGCTGTG TATTCAGCGG ATGAGTCTCT TTCTGCACAT 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036538.3
CDS	438..2843
Translation	MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHPSDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSVSNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGAEVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEEDLADSVGTEDCRINSAVYSADESLSAHK

Target ORF information:

RefSeq Version	NM_012406.3
Organism	Homo sapiens(human)
Definition	Homo sapiens PR/SET domain 4 (PRDM4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012406.3

ORF Insert Sequence:

ATGCATCACA GGATGAATGA AATGAACCTG AGTCCAGTGG GGATGGAGCA GCTGACTTCA 
TCCTCTGTGA GCAATGCCTT GCCAGTCTCA GGAAGTCACC TGGGATTGGC TGCCTCACCC 
ACTCACAGTG CCATCCCTGC CCCAGGCCTC CCAGTGGCAA TTCCAAACCT GGGTCCCTCC 
CTGAGCTCTC TGCCTTCTGC TCTGTCTTTA ATGCTACCAA TGGGTATTGG GGATCGAGGG 
GTGATGTGTG GGTTACCTGA AAGAAACTAC ACCCTACCTC CACCACCTTA CCCTCACCTG 
GAGAGCAGTT ATTTCAGAAC CATTCTACCT GGCATTTTAT CTTATTTAGC TGACAGACCA 
CCTCCACAGT ACATCCACCC TAACTCTATA AATGTTGATG GTAATACAGC ATTATCTATC 
ACCAATAACC CTTCAGCACT AGATCCCTAT CAGTCCAATG GAAATGTTGG ATTAGAACCA 
GGCATTGTTT CAATAGACTC TCGCTCTGTG AACACACATG GTGCCCAAAG TCTTCATCCC 
AGTGATGGCC ATGAGGTGGC CTTGGACACA GCAATCACTA TGGAGAACGT TTCTAGGGTT 
ACCAGCCCAA TTTCGACAGA TGGAATGGCA GAGGAGCTTA CGATGGACGG TGTTGCAGGC 
GAGCATTCCC AAATCCCAAA TGGCTCCAGA AGTCATGAAC CTCTGTCTGT GGATTCTGTG 
AGCAACAACC TTGCAGCAGA CGCTGTAGGA CATGGTGGTG TGATACCCAT GCATGGGAAT 
GGCCTGGAGC TCCCTGTGGT CATGGAGACA GACCACATTG CAAGTCGGGT CAATGGCATG 
TCTGACAGTG CCCTCAGTGA CTCCATTCAC ACTGTGGCCA TGAGCACCAA CTCTGTAAGC 
GTGGCACTCT CTACCTCACA CAACCTTGCC TCCCTAGAAT CTGTTTCCCT CCATGAAGTT 
GGCCTCAGCC TAGAACCTGT GGCTGTCTCC TCCATCACCC AGGAGGTTGC TATGGGGACA 
GGTCATGTAG ATGTATCTTC AGACAGTCTT TCTTTTGTAT CACCTTCACT GCAAATGGAA 
GACTCCAATT CAAACAAGGA GAACATGGCA ACCTTGTTTA CAATTTGGTG TACTCTGTGT 
GACCGCGCCT ATCCCTCGGA CTGTCCCGAA CATGGACCAG TGACTTTTGT TCCTGACACT 
CCAATAGAGA GCAGAGCAAG GCTTTCTCTC CCAAAGCAGC TTGTTCTCCG TCAGTCAATT 
GTGGGAGCAG AAGTTGGTGT ATGGACTGGA GAAACCATTC CTGTGCGGAC TTGCTTTGGA 
CCTCTAATTG GCCAGCAGAG TCACTCCATG GAAGTAGCAG AATGGACAGA CAAGGCAGTT 
AACCATATCT GGAAGATATA CCACAATGGT GTCCTAGAAT TCTGCATCAT TACAACTGAT 
GAAAATGAAT GTAATTGGAT GATGTTTGTG CGCAAAGCCA GGAACCGGGA AGAGCAGAAT 
TTGGTGGCTT ATCCTCATGA TGGAAAAATC TTTTTCTGCA CCTCACAAGA TATCCCTCCT 
GAAAATGAAC TGCTTTTTTA TTATAGCCGA GATTATGCTC AACAGATTGG TGTTCCTGAA 
CACCCAGATG TGCATCTCTG TAACTGTGGC AAGGAGTGCA ATTCTTACAC AGAGTTCAAA 
GCCCATCTGA CCAGCCACAT CCATAACCAT CTTCCTACCC AGGGACATAG CGGCAGCCAT 
GGGCCAAGTC ACAGCAAAGA AAGGAAGTGG AAGTGCTCAA TGTGCCCCCA AGCTTTTATC 
TCTCCTTCCA AACTTCATGT CCACTTTATG GGTCACATGG GTATGAAGCC CCACAAGTGT 
GATTTCTGTA GCAAGGCTTT TAGTGATCCC AGCAACCTGC GGACCCACCT CAAGATACAT 
ACAGGTCAGA AGAACTACAG GTGTACCTTG TGTGACAAGT CTTTCACCCA GAAGGCTCAC 
CTGGAGTCCC ACATGGTTAT CCACACTGGG GAGAAGAATC TTAAGTGTGA TTACTGTGAC 
AAGTTGTTTA TGCGGAGGCA GGACCTCAAG CAGCACGTGC TCATCCACAC TCAAGAACGC 
CAGATCAAGT GTCCCAAGTG TGATAAGCTG TTCTTGAGAA CAAATCACTT AAAGAAGCAT 
CTCAATTCTC ATGAAGGAAA ACGGGATTAT GTCTGTGAAA AATGTACAAA GGCTTATCTA 
ACCAAATACC ATCTCACCCG CCACCTGAAA ACCTGCAAAG GGCCCACCTC CAGTTCGTCA 
GCACCAGAGG AGGAAGAAGA GGATGACTCA GAAGAGGAAG ATCTAGCAGA CTCTGTGGGG 
ACAGAAGACT GTAGGATTAA CAGTGCTGTG TATTCAGCGG ATGAGTCTCT TTCTGCACAT 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRDM4 ( NM_012406.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_036538.3 Homo sapiens PR/SET domain 4 (PRDM4), mRNA.

Price & Availability↑

CloneID	OHu06214
Clone ID Related Accession (Same CDS sequence)	NM_012406.3 , NM_012406.4
Accession Version	NM_012406.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2406bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	PR domain zinc finger protein 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU502236.1, AK056378.1 and AL133083.1. On Nov 22, 2018 this sequence version replaced NM_012406.3. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.39635.1, SRR1660807.82133.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000228437.10/ ENSP00000228437.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCATCACA GGATGAATGA AATGAACCTG AGTCCAGTGG GGATGGAGCA GCTGACTTCA 
TCCTCTGTGA GCAATGCCTT GCCAGTCTCA GGAAGTCACC TGGGATTGGC TGCCTCACCC 
ACTCACAGTG CCATCCCTGC CCCAGGCCTC CCAGTGGCAA TTCCAAACCT GGGTCCCTCC 
CTGAGCTCTC TGCCTTCTGC TCTGTCTTTA ATGCTACCAA TGGGTATTGG GGATCGAGGG 
GTGATGTGTG GGTTACCTGA AAGAAACTAC ACCCTACCTC CACCACCTTA CCCTCACCTG 
GAGAGCAGTT ATTTCAGAAC CATTCTACCT GGCATTTTAT CTTATTTAGC TGACAGACCA 
CCTCCACAGT ACATCCACCC TAACTCTATA AATGTTGATG GTAATACAGC ATTATCTATC 
ACCAATAACC CTTCAGCACT AGATCCCTAT CAGTCCAATG GAAATGTTGG ATTAGAACCA 
GGCATTGTTT CAATAGACTC TCGCTCTGTG AACACACATG GTGCCCAAAG TCTTCATCCC 
AGTGATGGCC ATGAGGTGGC CTTGGACACA GCAATCACTA TGGAGAACGT TTCTAGGGTT 
ACCAGCCCAA TTTCGACAGA TGGAATGGCA GAGGAGCTTA CGATGGACGG TGTTGCAGGC 
GAGCATTCCC AAATCCCAAA TGGCTCCAGA AGTCATGAAC CTCTGTCTGT GGATTCTGTG 
AGCAACAACC TTGCAGCAGA CGCTGTAGGA CATGGTGGTG TGATACCCAT GCATGGGAAT 
GGCCTGGAGC TCCCTGTGGT CATGGAGACA GACCACATTG CAAGTCGGGT CAATGGCATG 
TCTGACAGTG CCCTCAGTGA CTCCATTCAC ACTGTGGCCA TGAGCACCAA CTCTGTAAGC 
GTGGCACTCT CTACCTCACA CAACCTTGCC TCCCTAGAAT CTGTTTCCCT CCATGAAGTT 
GGCCTCAGCC TAGAACCTGT GGCTGTCTCC TCCATCACCC AGGAGGTTGC TATGGGGACA 
GGTCATGTAG ATGTATCTTC AGACAGTCTT TCTTTTGTAT CACCTTCACT GCAAATGGAA 
GACTCCAATT CAAACAAGGA GAACATGGCA ACCTTGTTTA CAATTTGGTG TACTCTGTGT 
GACCGCGCCT ATCCCTCGGA CTGTCCCGAA CATGGACCAG TGACTTTTGT TCCTGACACT 
CCAATAGAGA GCAGAGCAAG GCTTTCTCTC CCAAAGCAGC TTGTTCTCCG TCAGTCAATT 
GTGGGAGCAG AAGTTGGTGT ATGGACTGGA GAAACCATTC CTGTGCGGAC TTGCTTTGGA 
CCTCTAATTG GCCAGCAGAG TCACTCCATG GAAGTAGCAG AATGGACAGA CAAGGCAGTT 
AACCATATCT GGAAGATATA CCACAATGGT GTCCTAGAAT TCTGCATCAT TACAACTGAT 
GAAAATGAAT GTAATTGGAT GATGTTTGTG CGCAAAGCCA GGAACCGGGA AGAGCAGAAT 
TTGGTGGCTT ATCCTCATGA TGGAAAAATC TTTTTCTGCA CCTCACAAGA TATCCCTCCT 
GAAAATGAAC TGCTTTTTTA TTATAGCCGA GATTATGCTC AACAGATTGG TGTTCCTGAA 
CACCCAGATG TGCATCTCTG TAACTGTGGC AAGGAGTGCA ATTCTTACAC AGAGTTCAAA 
GCCCATCTGA CCAGCCACAT CCATAACCAT CTTCCTACCC AGGGACATAG CGGCAGCCAT 
GGGCCAAGTC ACAGCAAAGA AAGGAAGTGG AAGTGCTCAA TGTGCCCCCA AGCTTTTATC 
TCTCCTTCCA AACTTCATGT CCACTTTATG GGTCACATGG GTATGAAGCC CCACAAGTGT 
GATTTCTGTA GCAAGGCTTT TAGTGATCCC AGCAACCTGC GGACCCACCT CAAGATACAT 
ACAGGTCAGA AGAACTACAG GTGTACCTTG TGTGACAAGT CTTTCACCCA GAAGGCTCAC 
CTGGAGTCCC ACATGGTTAT CCACACTGGG GAGAAGAATC TTAAGTGTGA TTACTGTGAC 
AAGTTGTTTA TGCGGAGGCA GGACCTCAAG CAGCACGTGC TCATCCACAC TCAAGAACGC 
CAGATCAAGT GTCCCAAGTG TGATAAGCTG TTCTTGAGAA CAAATCACTT AAAGAAGCAT 
CTCAATTCTC ATGAAGGAAA ACGGGATTAT GTCTGTGAAA AATGTACAAA GGCTTATCTA 
ACCAAATACC ATCTCACCCG CCACCTGAAA ACCTGCAAAG GGCCCACCTC CAGTTCGTCA 
GCACCAGAGG AGGAAGAAGA GGATGACTCA GAAGAGGAAG ATCTAGCAGA CTCTGTGGGG 
ACAGAAGACT GTAGGATTAA CAGTGCTGTG TATTCAGCGG ATGAGTCTCT TTCTGCACAT 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036538.3
CDS	438..2843
Translation	MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHPSDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSVSNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGAEVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEEDLADSVGTEDCRINSAVYSADESLSAHK

Target ORF information:

RefSeq Version	NM_012406.4
Organism	Homo sapiens(human)
Definition	Homo sapiens PR/SET domain 4 (PRDM4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012406.4

ORF Insert Sequence:

ATGCATCACA GGATGAATGA AATGAACCTG AGTCCAGTGG GGATGGAGCA GCTGACTTCA 
TCCTCTGTGA GCAATGCCTT GCCAGTCTCA GGAAGTCACC TGGGATTGGC TGCCTCACCC 
ACTCACAGTG CCATCCCTGC CCCAGGCCTC CCAGTGGCAA TTCCAAACCT GGGTCCCTCC 
CTGAGCTCTC TGCCTTCTGC TCTGTCTTTA ATGCTACCAA TGGGTATTGG GGATCGAGGG 
GTGATGTGTG GGTTACCTGA AAGAAACTAC ACCCTACCTC CACCACCTTA CCCTCACCTG 
GAGAGCAGTT ATTTCAGAAC CATTCTACCT GGCATTTTAT CTTATTTAGC TGACAGACCA 
CCTCCACAGT ACATCCACCC TAACTCTATA AATGTTGATG GTAATACAGC ATTATCTATC 
ACCAATAACC CTTCAGCACT AGATCCCTAT CAGTCCAATG GAAATGTTGG ATTAGAACCA 
GGCATTGTTT CAATAGACTC TCGCTCTGTG AACACACATG GTGCCCAAAG TCTTCATCCC 
AGTGATGGCC ATGAGGTGGC CTTGGACACA GCAATCACTA TGGAGAACGT TTCTAGGGTT 
ACCAGCCCAA TTTCGACAGA TGGAATGGCA GAGGAGCTTA CGATGGACGG TGTTGCAGGC 
GAGCATTCCC AAATCCCAAA TGGCTCCAGA AGTCATGAAC CTCTGTCTGT GGATTCTGTG 
AGCAACAACC TTGCAGCAGA CGCTGTAGGA CATGGTGGTG TGATACCCAT GCATGGGAAT 
GGCCTGGAGC TCCCTGTGGT CATGGAGACA GACCACATTG CAAGTCGGGT CAATGGCATG 
TCTGACAGTG CCCTCAGTGA CTCCATTCAC ACTGTGGCCA TGAGCACCAA CTCTGTAAGC 
GTGGCACTCT CTACCTCACA CAACCTTGCC TCCCTAGAAT CTGTTTCCCT CCATGAAGTT 
GGCCTCAGCC TAGAACCTGT GGCTGTCTCC TCCATCACCC AGGAGGTTGC TATGGGGACA 
GGTCATGTAG ATGTATCTTC AGACAGTCTT TCTTTTGTAT CACCTTCACT GCAAATGGAA 
GACTCCAATT CAAACAAGGA GAACATGGCA ACCTTGTTTA CAATTTGGTG TACTCTGTGT 
GACCGCGCCT ATCCCTCGGA CTGTCCCGAA CATGGACCAG TGACTTTTGT TCCTGACACT 
CCAATAGAGA GCAGAGCAAG GCTTTCTCTC CCAAAGCAGC TTGTTCTCCG TCAGTCAATT 
GTGGGAGCAG AAGTTGGTGT ATGGACTGGA GAAACCATTC CTGTGCGGAC TTGCTTTGGA 
CCTCTAATTG GCCAGCAGAG TCACTCCATG GAAGTAGCAG AATGGACAGA CAAGGCAGTT 
AACCATATCT GGAAGATATA CCACAATGGT GTCCTAGAAT TCTGCATCAT TACAACTGAT 
GAAAATGAAT GTAATTGGAT GATGTTTGTG CGCAAAGCCA GGAACCGGGA AGAGCAGAAT 
TTGGTGGCTT ATCCTCATGA TGGAAAAATC TTTTTCTGCA CCTCACAAGA TATCCCTCCT 
GAAAATGAAC TGCTTTTTTA TTATAGCCGA GATTATGCTC AACAGATTGG TGTTCCTGAA 
CACCCAGATG TGCATCTCTG TAACTGTGGC AAGGAGTGCA ATTCTTACAC AGAGTTCAAA 
GCCCATCTGA CCAGCCACAT CCATAACCAT CTTCCTACCC AGGGACATAG CGGCAGCCAT 
GGGCCAAGTC ACAGCAAAGA AAGGAAGTGG AAGTGCTCAA TGTGCCCCCA AGCTTTTATC 
TCTCCTTCCA AACTTCATGT CCACTTTATG GGTCACATGG GTATGAAGCC CCACAAGTGT 
GATTTCTGTA GCAAGGCTTT TAGTGATCCC AGCAACCTGC GGACCCACCT CAAGATACAT 
ACAGGTCAGA AGAACTACAG GTGTACCTTG TGTGACAAGT CTTTCACCCA GAAGGCTCAC 
CTGGAGTCCC ACATGGTTAT CCACACTGGG GAGAAGAATC TTAAGTGTGA TTACTGTGAC 
AAGTTGTTTA TGCGGAGGCA GGACCTCAAG CAGCACGTGC TCATCCACAC TCAAGAACGC 
CAGATCAAGT GTCCCAAGTG TGATAAGCTG TTCTTGAGAA CAAATCACTT AAAGAAGCAT 
CTCAATTCTC ATGAAGGAAA ACGGGATTAT GTCTGTGAAA AATGTACAAA GGCTTATCTA 
ACCAAATACC ATCTCACCCG CCACCTGAAA ACCTGCAAAG GGCCCACCTC CAGTTCGTCA 
GCACCAGAGG AGGAAGAAGA GGATGACTCA GAAGAGGAAG ATCTAGCAGA CTCTGTGGGG 
ACAGAAGACT GTAGGATTAA CAGTGCTGTG TATTCAGCGG ATGAGTCTCT TTCTGCACAT 
AAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRDM4 ( XM_005268593.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268650.1 Homo sapiens PR/SET domain 4 (PRDM4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu46269
Clone ID Related Accession (Same CDS sequence)	XM_005268593.1 , XM_024448807.1
Accession Version	XM_005268593.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2427bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	PR domain zinc finger protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCATCACA GGATGAATGA AATGAACCTG AGTCCAGTGG GGATGGAGCA GCTGACTTCA 
TCCTCTGTGA GCAATGCCTT GCCAGTCTCA GGAAGTCACC TGGGATTGGC TGCCTCACCC 
ACTCACAGTG CCATCCCTGC CCCAGGCCTC CCAGTGGCAA TTCCAAACCT GGGTCCCTCC 
CTGAGCTCTC TGCCTTCTGC TCTGTCTTTA ATGCTACCAA TGGGTATTGG GGATCGAGGG 
GTGATGTGTG GGTTACCTGA AAGAAACTAC ACCCTACCTC CACCACCTTA CCCTCACCTG 
GAGAGCAGTT ATTTCAGAAC CATTCTACCT GGCATTTTAT CTTATTTAGC TGACAGACCA 
CCTCCACAGT ACATCCACCC TAACTCTATA AATGTTGATG GTAATACAGC ATTATCTATC 
ACCAATAACC CTTCAGCACT AGATCCCTAT CAGTCCAATG GAAATGTTGG ATTAGAACCA 
GGCATTGTTT CAATAGACTC TCGCTCTGTG AACACACATG GTGCCCAAAG TCTTCATCCC 
AGTGATGGCC ATGAGGTGGC CTTGGACACA GCAATCACTA TGGAGAACGT TTCTAGGGTT 
ACCAGCCCAA TTTCGACAGA TGGAATGGCA GAGGAGCTTA CGATGGACGG TGTTGCAGGC 
GAGCATTCCC AAATCCCAAA TGGCTCCAGA AGTCATGAAC CTCTGTCTGT GGATTCTGTG 
AGCAACAACC TTGCAGCAGA CGCTGTAGGA CATGGTGGTG TGATACCCAT GCATGGGAAT 
GGCCTGGAGC TCCCTGTGGT CATGGAGACA GACCACATTG CAAGTCGGGT CAATGGCATG 
TCTGACAGTG CCCTCAGTGA CTCCATTCAC ACTGTGGCCA TGAGCACCAA CTCTGTAAGC 
GTGGCACTCT CTACCTCACA CAACCTTGCC TCCCTAGAAT CTGTTTCCCT CCATGAAGTT 
GGCCTCAGCC TAGAACCTGT GGCTGTCTCC TCCATCACCC AGGAGGTTGC TATGGGGACA 
GGTCATGTAG ATGTATCTTC AGACAGTCTT TCTTTTGTAT CACCTTCACT GCAAATGGAA 
GACTCCAATT CAAACAAGGA GAACATGGCA ACCTTGTTTA CAATTTGGTG TACTCTGTGT 
GACCGCGCCT ATCCCTCGGA CTGTCCCGAA CATGGACCAG TGACTTTTGT TCCTGACACT 
CCAATAGAGA GCAGAGCAAG GCTTTCTCTC CCAAAGCAGC TTGTTCTCCG TCAGTCAATT 
GTGGGAGCAG AAGTTGTTGG TGTCCTTCCA CTGACAGGTG TATGGACTGG AGAAACCATT 
CCTGTGCGGA CTTGCTTTGG ACCTCTAATT GGCCAGCAGA GTCACTCCAT GGAAGTAGCA 
GAATGGACAG ACAAGGCAGT TAACCATATC TGGAAGATAT ACCACAATGG TGTCCTAGAA 
TTCTGCATCA TTACAACTGA TGAAAATGAA TGTAATTGGA TGATGTTTGT GCGCAAAGCC 
AGGAACCGGG AAGAGCAGAA TTTGGTGGCT TATCCTCATG ATGGAAAAAT CTTTTTCTGC 
ACCTCACAAG ATATCCCTCC TGAAAATGAA CTGCTTTTTT ATTATAGCCG AGATTATGCT 
CAACAGATTG GTGTTCCTGA ACACCCAGAT GTGCATCTCT GTAACTGTGG CAAGGAGTGC 
AATTCTTACA CAGAGTTCAA AGCCCATCTG ACCAGCCACA TCCATAACCA TCTTCCTACC 
CAGGGACATA GCGGCAGCCA TGGGCCAAGT CACAGCAAAG AAAGGAAGTG GAAGTGCTCA 
ATGTGCCCCC AAGCTTTTAT CTCTCCTTCC AAACTTCATG TCCACTTTAT GGGTCACATG 
GGTATGAAGC CCCACAAGTG TGATTTCTGT AGCAAGGCTT TTAGTGATCC CAGCAACCTG 
CGGACCCACC TCAAGATACA TACAGGTCAG AAGAACTACA GGTGTACCTT GTGTGACAAG 
TCTTTCACCC AGAAGGCTCA CCTGGAGTCC CACATGGTTA TCCACACTGG GGAGAAGAAT 
CTTAAGTGTG ATTACTGTGA CAAGTTGTTT ATGCGGAGGC AGGACCTCAA GCAGCACGTG 
CTCATCCACA CTCAAGAACG CCAGATCAAG TGTCCCAAGT GTGATAAGCT GTTCTTGAGA 
ACAAATCACT TAAAGAAGCA TCTCAATTCT CATGAAGGAA AACGGGATTA TGTCTGTGAA 
AAATGTACAA AGGCTTATCT AACCAAATAC CATCTCACCC GCCACCTGAA AACCTGCAAA 
GGGCCCACCT CCAGTTCGTC AGCACCAGAG GAGGAAGAAG AGGATGACTC AGAAGAGGAA 
GATCTAGCAG ACTCTGTGGG GACAGAAGAC TGTAGGATTA ACAGTGCTGT GTATTCAGCG 
GATGAGTCTC TTTCTGCACA TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268650.1
CDS	436..2862
Translation	MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHPSDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSVSNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGAEVVGVLPLTGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEEDLADSVGTEDCRINSAVYSADESLSAHK

Target ORF information:

RefSeq Version	XM_005268593.1
Organism	Homo sapiens(human)
Definition	Homo sapiens PR/SET domain 4 (PRDM4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005268593.1

ORF Insert Sequence:

ATGCATCACA GGATGAATGA AATGAACCTG AGTCCAGTGG GGATGGAGCA GCTGACTTCA 
TCCTCTGTGA GCAATGCCTT GCCAGTCTCA GGAAGTCACC TGGGATTGGC TGCCTCACCC 
ACTCACAGTG CCATCCCTGC CCCAGGCCTC CCAGTGGCAA TTCCAAACCT GGGTCCCTCC 
CTGAGCTCTC TGCCTTCTGC TCTGTCTTTA ATGCTACCAA TGGGTATTGG GGATCGAGGG 
GTGATGTGTG GGTTACCTGA AAGAAACTAC ACCCTACCTC CACCACCTTA CCCTCACCTG 
GAGAGCAGTT ATTTCAGAAC CATTCTACCT GGCATTTTAT CTTATTTAGC TGACAGACCA 
CCTCCACAGT ACATCCACCC TAACTCTATA AATGTTGATG GTAATACAGC ATTATCTATC 
ACCAATAACC CTTCAGCACT AGATCCCTAT CAGTCCAATG GAAATGTTGG ATTAGAACCA 
GGCATTGTTT CAATAGACTC TCGCTCTGTG AACACACATG GTGCCCAAAG TCTTCATCCC 
AGTGATGGCC ATGAGGTGGC CTTGGACACA GCAATCACTA TGGAGAACGT TTCTAGGGTT 
ACCAGCCCAA TTTCGACAGA TGGAATGGCA GAGGAGCTTA CGATGGACGG TGTTGCAGGC 
GAGCATTCCC AAATCCCAAA TGGCTCCAGA AGTCATGAAC CTCTGTCTGT GGATTCTGTG 
AGCAACAACC TTGCAGCAGA CGCTGTAGGA CATGGTGGTG TGATACCCAT GCATGGGAAT 
GGCCTGGAGC TCCCTGTGGT CATGGAGACA GACCACATTG CAAGTCGGGT CAATGGCATG 
TCTGACAGTG CCCTCAGTGA CTCCATTCAC ACTGTGGCCA TGAGCACCAA CTCTGTAAGC 
GTGGCACTCT CTACCTCACA CAACCTTGCC TCCCTAGAAT CTGTTTCCCT CCATGAAGTT 
GGCCTCAGCC TAGAACCTGT GGCTGTCTCC TCCATCACCC AGGAGGTTGC TATGGGGACA 
GGTCATGTAG ATGTATCTTC AGACAGTCTT TCTTTTGTAT CACCTTCACT GCAAATGGAA 
GACTCCAATT CAAACAAGGA GAACATGGCA ACCTTGTTTA CAATTTGGTG TACTCTGTGT 
GACCGCGCCT ATCCCTCGGA CTGTCCCGAA CATGGACCAG TGACTTTTGT TCCTGACACT 
CCAATAGAGA GCAGAGCAAG GCTTTCTCTC CCAAAGCAGC TTGTTCTCCG TCAGTCAATT 
GTGGGAGCAG AAGTTGTTGG TGTCCTTCCA CTGACAGGTG TATGGACTGG AGAAACCATT 
CCTGTGCGGA CTTGCTTTGG ACCTCTAATT GGCCAGCAGA GTCACTCCAT GGAAGTAGCA 
GAATGGACAG ACAAGGCAGT TAACCATATC TGGAAGATAT ACCACAATGG TGTCCTAGAA 
TTCTGCATCA TTACAACTGA TGAAAATGAA TGTAATTGGA TGATGTTTGT GCGCAAAGCC 
AGGAACCGGG AAGAGCAGAA TTTGGTGGCT TATCCTCATG ATGGAAAAAT CTTTTTCTGC 
ACCTCACAAG ATATCCCTCC TGAAAATGAA CTGCTTTTTT ATTATAGCCG AGATTATGCT 
CAACAGATTG GTGTTCCTGA ACACCCAGAT GTGCATCTCT GTAACTGTGG CAAGGAGTGC 
AATTCTTACA CAGAGTTCAA AGCCCATCTG ACCAGCCACA TCCATAACCA TCTTCCTACC 
CAGGGACATA GCGGCAGCCA TGGGCCAAGT CACAGCAAAG AAAGGAAGTG GAAGTGCTCA 
ATGTGCCCCC AAGCTTTTAT CTCTCCTTCC AAACTTCATG TCCACTTTAT GGGTCACATG 
GGTATGAAGC CCCACAAGTG TGATTTCTGT AGCAAGGCTT TTAGTGATCC CAGCAACCTG 
CGGACCCACC TCAAGATACA TACAGGTCAG AAGAACTACA GGTGTACCTT GTGTGACAAG 
TCTTTCACCC AGAAGGCTCA CCTGGAGTCC CACATGGTTA TCCACACTGG GGAGAAGAAT 
CTTAAGTGTG ATTACTGTGA CAAGTTGTTT ATGCGGAGGC AGGACCTCAA GCAGCACGTG 
CTCATCCACA CTCAAGAACG CCAGATCAAG TGTCCCAAGT GTGATAAGCT GTTCTTGAGA 
ACAAATCACT TAAAGAAGCA TCTCAATTCT CATGAAGGAA AACGGGATTA TGTCTGTGAA 
AAATGTACAA AGGCTTATCT AACCAAATAC CATCTCACCC GCCACCTGAA AACCTGCAAA 
GGGCCCACCT CCAGTTCGTC AGCACCAGAG GAGGAAGAAG AGGATGACTC AGAAGAGGAA 
GATCTAGCAG ACTCTGTGGG GACAGAAGAC TGTAGGATTA ACAGTGCTGT GTATTCAGCG 
GATGAGTCTC TTTCTGCACA TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRDM4 ( XM_024448807.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024304575.1 Homo sapiens PR/SET domain 4 (PRDM4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu46269
Clone ID Related Accession (Same CDS sequence)	XM_005268593.1 , XM_024448807.1
Accession Version	XM_024448807.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2427bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	PR domain zinc finger protein 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCATCACA GGATGAATGA AATGAACCTG AGTCCAGTGG GGATGGAGCA GCTGACTTCA 
TCCTCTGTGA GCAATGCCTT GCCAGTCTCA GGAAGTCACC TGGGATTGGC TGCCTCACCC 
ACTCACAGTG CCATCCCTGC CCCAGGCCTC CCAGTGGCAA TTCCAAACCT GGGTCCCTCC 
CTGAGCTCTC TGCCTTCTGC TCTGTCTTTA ATGCTACCAA TGGGTATTGG GGATCGAGGG 
GTGATGTGTG GGTTACCTGA AAGAAACTAC ACCCTACCTC CACCACCTTA CCCTCACCTG 
GAGAGCAGTT ATTTCAGAAC CATTCTACCT GGCATTTTAT CTTATTTAGC TGACAGACCA 
CCTCCACAGT ACATCCACCC TAACTCTATA AATGTTGATG GTAATACAGC ATTATCTATC 
ACCAATAACC CTTCAGCACT AGATCCCTAT CAGTCCAATG GAAATGTTGG ATTAGAACCA 
GGCATTGTTT CAATAGACTC TCGCTCTGTG AACACACATG GTGCCCAAAG TCTTCATCCC 
AGTGATGGCC ATGAGGTGGC CTTGGACACA GCAATCACTA TGGAGAACGT TTCTAGGGTT 
ACCAGCCCAA TTTCGACAGA TGGAATGGCA GAGGAGCTTA CGATGGACGG TGTTGCAGGC 
GAGCATTCCC AAATCCCAAA TGGCTCCAGA AGTCATGAAC CTCTGTCTGT GGATTCTGTG 
AGCAACAACC TTGCAGCAGA CGCTGTAGGA CATGGTGGTG TGATACCCAT GCATGGGAAT 
GGCCTGGAGC TCCCTGTGGT CATGGAGACA GACCACATTG CAAGTCGGGT CAATGGCATG 
TCTGACAGTG CCCTCAGTGA CTCCATTCAC ACTGTGGCCA TGAGCACCAA CTCTGTAAGC 
GTGGCACTCT CTACCTCACA CAACCTTGCC TCCCTAGAAT CTGTTTCCCT CCATGAAGTT 
GGCCTCAGCC TAGAACCTGT GGCTGTCTCC TCCATCACCC AGGAGGTTGC TATGGGGACA 
GGTCATGTAG ATGTATCTTC AGACAGTCTT TCTTTTGTAT CACCTTCACT GCAAATGGAA 
GACTCCAATT CAAACAAGGA GAACATGGCA ACCTTGTTTA CAATTTGGTG TACTCTGTGT 
GACCGCGCCT ATCCCTCGGA CTGTCCCGAA CATGGACCAG TGACTTTTGT TCCTGACACT 
CCAATAGAGA GCAGAGCAAG GCTTTCTCTC CCAAAGCAGC TTGTTCTCCG TCAGTCAATT 
GTGGGAGCAG AAGTTGTTGG TGTCCTTCCA CTGACAGGTG TATGGACTGG AGAAACCATT 
CCTGTGCGGA CTTGCTTTGG ACCTCTAATT GGCCAGCAGA GTCACTCCAT GGAAGTAGCA 
GAATGGACAG ACAAGGCAGT TAACCATATC TGGAAGATAT ACCACAATGG TGTCCTAGAA 
TTCTGCATCA TTACAACTGA TGAAAATGAA TGTAATTGGA TGATGTTTGT GCGCAAAGCC 
AGGAACCGGG AAGAGCAGAA TTTGGTGGCT TATCCTCATG ATGGAAAAAT CTTTTTCTGC 
ACCTCACAAG ATATCCCTCC TGAAAATGAA CTGCTTTTTT ATTATAGCCG AGATTATGCT 
CAACAGATTG GTGTTCCTGA ACACCCAGAT GTGCATCTCT GTAACTGTGG CAAGGAGTGC 
AATTCTTACA CAGAGTTCAA AGCCCATCTG ACCAGCCACA TCCATAACCA TCTTCCTACC 
CAGGGACATA GCGGCAGCCA TGGGCCAAGT CACAGCAAAG AAAGGAAGTG GAAGTGCTCA 
ATGTGCCCCC AAGCTTTTAT CTCTCCTTCC AAACTTCATG TCCACTTTAT GGGTCACATG 
GGTATGAAGC CCCACAAGTG TGATTTCTGT AGCAAGGCTT TTAGTGATCC CAGCAACCTG 
CGGACCCACC TCAAGATACA TACAGGTCAG AAGAACTACA GGTGTACCTT GTGTGACAAG 
TCTTTCACCC AGAAGGCTCA CCTGGAGTCC CACATGGTTA TCCACACTGG GGAGAAGAAT 
CTTAAGTGTG ATTACTGTGA CAAGTTGTTT ATGCGGAGGC AGGACCTCAA GCAGCACGTG 
CTCATCCACA CTCAAGAACG CCAGATCAAG TGTCCCAAGT GTGATAAGCT GTTCTTGAGA 
ACAAATCACT TAAAGAAGCA TCTCAATTCT CATGAAGGAA AACGGGATTA TGTCTGTGAA 
AAATGTACAA AGGCTTATCT AACCAAATAC CATCTCACCC GCCACCTGAA AACCTGCAAA 
GGGCCCACCT CCAGTTCGTC AGCACCAGAG GAGGAAGAAG AGGATGACTC AGAAGAGGAA 
GATCTAGCAG ACTCTGTGGG GACAGAAGAC TGTAGGATTA ACAGTGCTGT GTATTCAGCG 
GATGAGTCTC TTTCTGCACA TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024304575.1
CDS	399..2825
Translation	MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHPSDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSVSNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGAEVVGVLPLTGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEEDLADSVGTEDCRINSAVYSADESLSAHK

Target ORF information:

RefSeq Version	XM_024448807.1
Organism	Homo sapiens(human)
Definition	Homo sapiens PR/SET domain 4 (PRDM4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024448807.1

ORF Insert Sequence:

ATGCATCACA GGATGAATGA AATGAACCTG AGTCCAGTGG GGATGGAGCA GCTGACTTCA 
TCCTCTGTGA GCAATGCCTT GCCAGTCTCA GGAAGTCACC TGGGATTGGC TGCCTCACCC 
ACTCACAGTG CCATCCCTGC CCCAGGCCTC CCAGTGGCAA TTCCAAACCT GGGTCCCTCC 
CTGAGCTCTC TGCCTTCTGC TCTGTCTTTA ATGCTACCAA TGGGTATTGG GGATCGAGGG 
GTGATGTGTG GGTTACCTGA AAGAAACTAC ACCCTACCTC CACCACCTTA CCCTCACCTG 
GAGAGCAGTT ATTTCAGAAC CATTCTACCT GGCATTTTAT CTTATTTAGC TGACAGACCA 
CCTCCACAGT ACATCCACCC TAACTCTATA AATGTTGATG GTAATACAGC ATTATCTATC 
ACCAATAACC CTTCAGCACT AGATCCCTAT CAGTCCAATG GAAATGTTGG ATTAGAACCA 
GGCATTGTTT CAATAGACTC TCGCTCTGTG AACACACATG GTGCCCAAAG TCTTCATCCC 
AGTGATGGCC ATGAGGTGGC CTTGGACACA GCAATCACTA TGGAGAACGT TTCTAGGGTT 
ACCAGCCCAA TTTCGACAGA TGGAATGGCA GAGGAGCTTA CGATGGACGG TGTTGCAGGC 
GAGCATTCCC AAATCCCAAA TGGCTCCAGA AGTCATGAAC CTCTGTCTGT GGATTCTGTG 
AGCAACAACC TTGCAGCAGA CGCTGTAGGA CATGGTGGTG TGATACCCAT GCATGGGAAT 
GGCCTGGAGC TCCCTGTGGT CATGGAGACA GACCACATTG CAAGTCGGGT CAATGGCATG 
TCTGACAGTG CCCTCAGTGA CTCCATTCAC ACTGTGGCCA TGAGCACCAA CTCTGTAAGC 
GTGGCACTCT CTACCTCACA CAACCTTGCC TCCCTAGAAT CTGTTTCCCT CCATGAAGTT 
GGCCTCAGCC TAGAACCTGT GGCTGTCTCC TCCATCACCC AGGAGGTTGC TATGGGGACA 
GGTCATGTAG ATGTATCTTC AGACAGTCTT TCTTTTGTAT CACCTTCACT GCAAATGGAA 
GACTCCAATT CAAACAAGGA GAACATGGCA ACCTTGTTTA CAATTTGGTG TACTCTGTGT 
GACCGCGCCT ATCCCTCGGA CTGTCCCGAA CATGGACCAG TGACTTTTGT TCCTGACACT 
CCAATAGAGA GCAGAGCAAG GCTTTCTCTC CCAAAGCAGC TTGTTCTCCG TCAGTCAATT 
GTGGGAGCAG AAGTTGTTGG TGTCCTTCCA CTGACAGGTG TATGGACTGG AGAAACCATT 
CCTGTGCGGA CTTGCTTTGG ACCTCTAATT GGCCAGCAGA GTCACTCCAT GGAAGTAGCA 
GAATGGACAG ACAAGGCAGT TAACCATATC TGGAAGATAT ACCACAATGG TGTCCTAGAA 
TTCTGCATCA TTACAACTGA TGAAAATGAA TGTAATTGGA TGATGTTTGT GCGCAAAGCC 
AGGAACCGGG AAGAGCAGAA TTTGGTGGCT TATCCTCATG ATGGAAAAAT CTTTTTCTGC 
ACCTCACAAG ATATCCCTCC TGAAAATGAA CTGCTTTTTT ATTATAGCCG AGATTATGCT 
CAACAGATTG GTGTTCCTGA ACACCCAGAT GTGCATCTCT GTAACTGTGG CAAGGAGTGC 
AATTCTTACA CAGAGTTCAA AGCCCATCTG ACCAGCCACA TCCATAACCA TCTTCCTACC 
CAGGGACATA GCGGCAGCCA TGGGCCAAGT CACAGCAAAG AAAGGAAGTG GAAGTGCTCA 
ATGTGCCCCC AAGCTTTTAT CTCTCCTTCC AAACTTCATG TCCACTTTAT GGGTCACATG 
GGTATGAAGC CCCACAAGTG TGATTTCTGT AGCAAGGCTT TTAGTGATCC CAGCAACCTG 
CGGACCCACC TCAAGATACA TACAGGTCAG AAGAACTACA GGTGTACCTT GTGTGACAAG 
TCTTTCACCC AGAAGGCTCA CCTGGAGTCC CACATGGTTA TCCACACTGG GGAGAAGAAT 
CTTAAGTGTG ATTACTGTGA CAAGTTGTTT ATGCGGAGGC AGGACCTCAA GCAGCACGTG 
CTCATCCACA CTCAAGAACG CCAGATCAAG TGTCCCAAGT GTGATAAGCT GTTCTTGAGA 
ACAAATCACT TAAAGAAGCA TCTCAATTCT CATGAAGGAA AACGGGATTA TGTCTGTGAA 
AAATGTACAA AGGCTTATCT AACCAAATAC CATCTCACCC GCCACCTGAA AACCTGCAAA 
GGGCCCACCT CCAGTTCGTC AGCACCAGAG GAGGAAGAAG AGGATGACTC AGAAGAGGAA 
GATCTAGCAG ACTCTGTGGG GACAGAAGAC TGTAGGATTA ACAGTGCTGT GTATTCAGCG 
GATGAGTCTC TTTCTGCACA TAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of Prdm genes in human corneal endothelium.
Experimental eye research159114-122(2017 06)
Rolev K,O'Donovan DG,Georgiou C,Rajan MS,Chittka A

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
Nature communications54020(2014 Jun)
Navarini AA,Simpson MA,Weale M,Knight J,Carlavan I,Reiniche P,Burden DA,Layton A,Bataille V,Allen M,Pleass R,Pink A,Creamer D,English J,Munn S,Walton S,,Willis C,D?ret S,Voegel JJ,Spector T,Smith CH,Trembath RC,Barker JN

Transcription factor positive regulatory domain 4 (PRDM4) recruits protein arginine methyltransferase 5 (PRMT5) to mediate histone arginine methylation and control neural stem cell proliferation and differentiation.
The Journal of biological chemistry287(51)42995-3006(2012 Dec)
Chittka A,Nitarska J,Grazini U,Richardson WD

The PR/SET domain in PRDM4 is preceded by a zinc knuckle.
Proteins79(7)2341-5(2011 Jul)
Briknarov? K,Atwater DZ,Glicken JM,Maynard SJ,Ness TE

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PRDM4 cDNA ORF clone, Homo sapiens(human)

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