Gene Symbol | PARP3 |
Entrez Gene ID | 10039 |
Full Name | poly(ADP-ribose) polymerase family member 3 |
Synonyms | ADPRT3,ADPRTL2,ADPRTL3,ARTD3,IRT1,PADPRT-3 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(Human) |
Genome | |
Summary | The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]. |
Disorder MIM: |