Hsp26 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hsp26
Entrez Gene ID	39075
Full Name	Heat shock protein 26
Synonyms	26,26K,CG4183,DmHsp26,Dmel23.0,Dmel\CG4183,HSP26,hsp 26,hsp26,small hsp locus 67B
General protein information	Preferred Names Heat shock protein 26 Names CG4183 gene product from transcript CG4183-RB CG4183-PA CG4183-PB Hsp 26 Hsp26-PA Hsp26-PB heat shock protein 26 heat shock protein hsp26 protein 26
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3L Map Location: 67B2-67B2

mRNA and Protein(s)

mRNA	Protein	Name
NM_001300071.1	NP_001287000.1	heat shock protein 26, isoform B
NM_079273.3	NP_523997.1	heat shock protein 26, isoform A

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	Hsp23	NP_001246694.1
Drosophila melanogaster (fruit fly)	Hsp27	NP_524000.1
Drosophila melanogaster (fruit fly)	Hsp22	NP_001027114.1
Drosophila melanogaster (fruit fly)	Hsp26	NP_523997.1
Drosophila melanogaster (fruit fly)	Hsp67Ba	NP_523998.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The study provides evidence for the attenuation of cellular and functional decline in aged Drosophila after prolonged DCA exposure and the effect of hsp27 modulation which further incites studies towards the therapeutic application of DCA.
Title: Long-term dietary exposure to low concentration of dichloroacetic acid promoted longevity and attenuated cellular and functional declines in aged Drosophila melanogaster.

The functional similarities and differences of neuronal expression of hsp26 and hsp27 in adult Drosophila were demonstrated.
Title: The effect of neuronal expression of heat shock proteins 26 and 27 on lifespan, neurodegeneration, and apoptosis in Drosophila.

Hsp26 overexpression in larva had only a small thermoprotective effect on locomotion and no effect on neural function.
Title: Tissue-specific targeting of Hsp26 has no effect on heat resistance of neural function in larval Drosophila.

Data show that overexpression of either heat-shock proteins 26 or 27 extended the mean lifespan by 30%, and the flies also displayed increased stress resistance.
Title: Multiple-stress analysis for isolation of Drosophila longevity genes.

GAGA factor and the TFIID complex collaborate in generating an open chromatin structure at the Drosophila melanogaster hsp26 promoter.
Title: GAGA factor and the TFIID complex collaborate in generating an open chromatin structure at the Drosophila melanogaster hsp26 promoter.

The following Hsp26 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hsp26 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa18021	NM_079273.3 Latest version!	Drosophila melanogaster heat shock protein 26, transcript variant A (Hsp26), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OFa18021	NM_001300071.1 Latest version!	Drosophila melanogaster heat shock protein 26, transcript variant B (Hsp26), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hsp26 ( NM_001300071.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001287000.1 Drosophila melanogaster heat shock protein 26, transcript variant B (Hsp26), mRNA.

Price & Availability↑

CloneID	OFa18021
Clone ID Related Accession (Same CDS sequence)	NM_001300071.1 , NM_079273.3
Accession Version	NM_001300071.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	heat shock protein 26, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCGCTAT CTACTCTGCT TTCGCTTGTG GATGAACTCC AGGAGCCCCG CAGCCCCATC 
TACGAGCTTG GACTGGGATT GCATCCGCAT TCCCGCTACG TGCTGCCCCT TGGCACTCAG 
CAGCGCCGTT CCATCAACGG ATGCCCTTGC GCATCGCCGA TATGCCCATC GTCGCCCGCC 
GGCCAGGTTT TGGCTTTGCG GCGCGAGATG GCCAACCGCA ACGACATTCA CTGGCCGGCA 
ACCGCCCATG TGGGCAAGGA TGGATTCCAG GTGTGCATGG ACGTCGCCCA GTTCAAGCCC 
AGTGAGCTCA ACGTGAAGGT GGTGGACGAC TCCATCTTGG TCGAGGGCAA GCATGAGGAA 
CGCCAGGACG ACCATGGTCA CATCATGCGC CACTTTGTGC GCCGCTACAA GGTTCCCGAT 
GGCTACAAGG CGGAGCAAGT GGTCTCGCAG CTGTCGTCGG ATGGCGTGCT CACCGTCAGT 
ATTCCCAAGC CGCAGGCCGT CGAGGACAAG TCCAAGGAGC GCATCATTCA AATTCAGCAA 
GTGGGACCCG CTCACCTCAA CGTTAAGGCA AATGAAAGCG AGGTGAAGGG CAAGGAGAAC 
GGAGCACCCA ACGGCAAGGA CAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001287000.1
CDS	240..866
Translation	MSLSTLLSLVDELQEPRSPIYELGLGLHPHSRYVLPLGTQQRRSINGCPCASPICPSSPAGQVLALRREMANRNDIHWPATAHVGKDGFQVCMDVAQFKPSELNVKVVDDSILVEGKHEERQDDHGHIMRHFVRRYKVPDGYKAEQVVSQLSSDGVLTVSIPKPQAVEDKSKERIIQIQQVGPAHLNVKANESEVKGKENGAPNGKDK

Target ORF information:

RefSeq Version	NM_001300071.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster heat shock protein 26, transcript variant B (Hsp26), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001300071.1

ORF Insert Sequence:

ATGTCGCTAT CTACTCTGCT TTCGCTTGTG GATGAACTCC AGGAGCCCCG CAGCCCCATC 
TACGAGCTTG GACTGGGATT GCATCCGCAT TCCCGCTACG TGCTGCCCCT TGGCACTCAG 
CAGCGCCGTT CCATCAACGG ATGCCCTTGC GCATCGCCGA TATGCCCATC GTCGCCCGCC 
GGCCAGGTTT TGGCTTTGCG GCGCGAGATG GCCAACCGCA ACGACATTCA CTGGCCGGCA 
ACCGCCCATG TGGGCAAGGA TGGATTCCAG GTGTGCATGG ACGTCGCCCA GTTCAAGCCC 
AGTGAGCTCA ACGTGAAGGT GGTGGACGAC TCCATCTTGG TCGAGGGCAA GCATGAGGAA 
CGCCAGGACG ACCATGGTCA CATCATGCGC CACTTTGTGC GCCGCTACAA GGTTCCCGAT 
GGCTACAAGG CGGAGCAAGT GGTCTCGCAG CTGTCGTCGG ATGGCGTGCT CACCGTCAGT 
ATTCCCAAGC CGCAGGCCGT CGAGGACAAG TCCAAGGAGC GCATCATTCA AATTCAGCAA 
GTGGGACCCG CTCACCTCAA CGTTAAGGCA AATGAAAGCG AGGTGAAGGG CAAGGAGAAC 
GGAGCACCCA ACGGCAAGGA CAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Hsp26 ( NM_079273.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_523997.1 Drosophila melanogaster heat shock protein 26, transcript variant A (Hsp26), mRNA.

Price & Availability↑

CloneID	OFa18021
Clone ID Related Accession (Same CDS sequence)	NM_001300071.1 , NM_079273.3
Accession Version	NM_079273.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	heat shock protein 26, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_079273.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTCGCTAT CTACTCTGCT TTCGCTTGTG GATGAACTCC AGGAGCCCCG CAGCCCCATC 
TACGAGCTTG GACTGGGATT GCATCCGCAT TCCCGCTACG TGCTGCCCCT TGGCACTCAG 
CAGCGCCGTT CCATCAACGG ATGCCCTTGC GCATCGCCGA TATGCCCATC GTCGCCCGCC 
GGCCAGGTTT TGGCTTTGCG GCGCGAGATG GCCAACCGCA ACGACATTCA CTGGCCGGCA 
ACCGCCCATG TGGGCAAGGA TGGATTCCAG GTGTGCATGG ACGTCGCCCA GTTCAAGCCC 
AGTGAGCTCA ACGTGAAGGT GGTGGACGAC TCCATCTTGG TCGAGGGCAA GCATGAGGAA 
CGCCAGGACG ACCATGGTCA CATCATGCGC CACTTTGTGC GCCGCTACAA GGTTCCCGAT 
GGCTACAAGG CGGAGCAAGT GGTCTCGCAG CTGTCGTCGG ATGGCGTGCT CACCGTCAGT 
ATTCCCAAGC CGCAGGCCGT CGAGGACAAG TCCAAGGAGC GCATCATTCA AATTCAGCAA 
GTGGGACCCG CTCACCTCAA CGTTAAGGCA AATGAAAGCG AGGTGAAGGG CAAGGAGAAC 
GGAGCACCCA ACGGCAAGGA CAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_523997.1
CDS	188..814
Translation	MSLSTLLSLVDELQEPRSPIYELGLGLHPHSRYVLPLGTQQRRSINGCPCASPICPSSPAGQVLALRREMANRNDIHWPATAHVGKDGFQVCMDVAQFKPSELNVKVVDDSILVEGKHEERQDDHGHIMRHFVRRYKVPDGYKAEQVVSQLSSDGVLTVSIPKPQAVEDKSKERIIQIQQVGPAHLNVKANESEVKGKENGAPNGKDK

Target ORF information:

RefSeq Version	NM_079273.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster heat shock protein 26, transcript variant A (Hsp26), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079273.3

ORF Insert Sequence:

ATGTCGCTAT CTACTCTGCT TTCGCTTGTG GATGAACTCC AGGAGCCCCG CAGCCCCATC 
TACGAGCTTG GACTGGGATT GCATCCGCAT TCCCGCTACG TGCTGCCCCT TGGCACTCAG 
CAGCGCCGTT CCATCAACGG ATGCCCTTGC GCATCGCCGA TATGCCCATC GTCGCCCGCC 
GGCCAGGTTT TGGCTTTGCG GCGCGAGATG GCCAACCGCA ACGACATTCA CTGGCCGGCA 
ACCGCCCATG TGGGCAAGGA TGGATTCCAG GTGTGCATGG ACGTCGCCCA GTTCAAGCCC 
AGTGAGCTCA ACGTGAAGGT GGTGGACGAC TCCATCTTGG TCGAGGGCAA GCATGAGGAA 
CGCCAGGACG ACCATGGTCA CATCATGCGC CACTTTGTGC GCCGCTACAA GGTTCCCGAT 
GGCTACAAGG CGGAGCAAGT GGTCTCGCAG CTGTCGTCGG ATGGCGTGCT CACCGTCAGT 
ATTCCCAAGC CGCAGGCCGT CGAGGACAAG TCCAAGGAGC GCATCATTCA AATTCAGCAA 
GTGGGACCCG CTCACCTCAA CGTTAAGGCA AATGAAAGCG AGGTGAAGGG CAAGGAGAAC 
GGAGCACCCA ACGGCAAGGA CAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Hsp26 cDNA ORF clone, Drosophila melanogaster(fruit fly)

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Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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