Gene Symbol | mec-10 |
Entrez Gene ID | 181101 |
Full Name | Degenerin mec-10 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » mec-10 cDNA ORF clone
Gene Symbol | mec-10 |
Entrez Gene ID | 181101 |
Full Name | Degenerin mec-10 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_077037.4 | NP_509438.1 | Degenerin mec-10 |
NM_077037.6 | NP_509438.1 | Degenerin mec-10 |
SCNN1G | XP_001093466.1 | |
Mus musculus (house mouse) | Scnn1g | NP_035456.1 |
Caenorhabditis elegans (roundworm) | asic-1 | NP_491214.3 |
Caenorhabditis elegans (roundworm) | mec-4 | NP_510712.2 |
Caenorhabditis elegans (roundworm) | del-1 | NP_510380.1 |
Caenorhabditis elegans (roundworm) | unc-8 | NP_501138.1 |
Xenopus tropicalis (tropical clawed frog) | scnn1g | XP_004918046.1 |
Pan troglodytes (chimpanzee) | SCNN1G | XP_003315070.1 |
Caenorhabditis elegans (roundworm) | unc-105 | NP_001254142.1 |
Caenorhabditis elegans (roundworm) | asic-2 | NP_492099.1 |
Caenorhabditis elegans (roundworm) | mec-10 | NP_509438.1 |
Bos taurus (cattle) | SCNN1G | NP_001180103.1 |
Gallus gallus (chicken) | SCNN1G | XP_414880.2 |
Homo sapiens (human) | SCNN1G | NP_001030.2 |
Rattus norvegicus (Norway rat) | Scnn1g | NP_058742.1 |
Canis lupus familiaris (dog) | SCNN1G | XP_547093.2 |
Caenorhabditis elegans (roundworm) | deg-1 | NP_509311.1 |
Caenorhabditis elegans (roundworm) | del-4 | NP_492230.2 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
LSS response was largely abolished by MEC-10 mutations encoded by a touch-insensitive mec-10 allele, providing a correlation between the channel's responses to two different mechanical forces
Title: Activation of the Caenorhabditis elegans Degenerin Channel by Shear Stress Requires the MEC-10 Subunit.
MEC-10, but not MEC-6, forms puncta in touch receptor neurites that colocalize with MEC-4 when MEC-4 is overexpressed in the touch receptor neurons
Title: Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans.
This study suggested that mutant MEC-10 proteins may affect channel current via MEC-2.
Title: The DEG/ENaC protein MEC-10 regulates the transduction channel complex in Caenorhabditis elegans touch receptor neurons.
MEC-10 protein is asymmetrically distributed within the touch neuron process. It may contribute to only a subset of gentle touch mechanosensory complexes found preferentially at the proximal dendrite.
Title: Spatial asymmetry in the mechanosensory phenotypes of the C. elegans DEG/ENaC gene mec-10.
harsh touch specifically required the DEG/ENaC proteins MEC-10 and DEGT-1 (F25D1.4), which represent putative components of a harsh touch mechanotransduction complex; responses to cold required the TRPA-1 channel and were MEC-10 and DEGT-1 independent
Title: Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors.
The following mec-10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mec-10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa349708 | |
Clone ID Related Accession (Same CDS sequence) | NM_077037.4 , NM_077037.6 | |
Accession Version | NM_077037.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2175bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Degenerin mec-10 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_077037.3. COMPLETENESS: incomplete on both ends. |
1 | ATGAATCGAA ACCCGCGAAT GTCAAAATTT CAACCAAATC CTCGTAGTCG CAGTCGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_509438.1 |
CDS | 1..2175 |
Translation |
Target ORF information:
Target ORF information:
|
NM_077037.4 |
1 | ATGAATCGAA ACCCGCGAAT GTCAAAATTT CAACCAAATC CTCGTAGTCG CAGTCGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349708 | |
Clone ID Related Accession (Same CDS sequence) | NM_077037.4 , NM_077037.6 | |
Accession Version | NM_077037.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2175bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Degenerin mec-10 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Oct 18, 2019 this sequence version replaced NM_077037.5. |
1 | ATGAATCGAA ACCCGCGAAT GTCAAAATTT CAACCAAATC CTCGTAGTCG CAGTCGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_509438.1 |
CDS | 75..2249 |
Translation |
Target ORF information:
Target ORF information:
|
NM_077037.6 |
1 | ATGAATCGAA ACCCGCGAAT GTCAAAATTT CAACCAAATC CTCGTAGTCG CAGTCGATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |