Gene Symbol | CYP27A1 |
Entrez Gene ID | 511960 |
Full Name | cytochrome P450, family 27, subfamily A, polypeptide 1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » CYP27A1 cDNA ORF clone
Gene Symbol | CYP27A1 |
Entrez Gene ID | 511960 |
Full Name | cytochrome P450, family 27, subfamily A, polypeptide 1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_001083413.2 | NP_001076882.1 | sterol 26-hydroxylase, mitochondrial |
Bos taurus (cattle) | CYP27A1 | NP_001076882.1 |
Danio rerio (zebrafish) | cyp27a7 | XP_002663445.1 |
Xenopus tropicalis (tropical clawed frog) | cyp27a1 | XP_002933986.2 |
Xenopus tropicalis (tropical clawed frog) | cyp27b1 | XP_002934002.2 |
Homo sapiens (human) | CYP27A1 | NP_000775.1 |
CYP27A1 | XP_001095424.1 | |
Canis lupus familiaris (dog) | CYP27A1 | XP_853094.3 |
Danio rerio (zebrafish) | cyp27a1.4 | XP_001923080.3 |
Xenopus tropicalis (tropical clawed frog) | LOC100496109 | XP_002933985.2 |
Xenopus tropicalis (tropical clawed frog) | cyp27a1 | XP_002934001.2 |
Pan troglodytes (chimpanzee) | LOC459951 | XP_001159436.1 |
Rattus norvegicus (Norway rat) | Cyp27a1 | NP_849178.2 |
Danio rerio (zebrafish) | zgc:136333 | NP_001038769.1 |
Danio rerio (zebrafish) | cyp27a1.2 | XP_001334004.3 |
Drosophila melanogaster (fruit fly) | Cyp49a1 | NP_001246256.1 |
Mus musculus (house mouse) | Cyp27a1 | NP_077226.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005774 | XP_315789.4 |
Gallus gallus (chicken) | CYP27A1 | XP_422056.3 |
Posttranslational modification by an isolevuglandin diminishes activity of the mitochondrial cytochrome P450 27A1.
Charvet CD, Laird J, Xu Y, Salomon RG, Pikuleva IA
Journal of lipid research54(5)1421-9(2013 May)
Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1.
Heo GY, Liao WL, Turko IV, Pikuleva IA
Archives of biochemistry and biophysics518(2)119-26(2012 Feb)
Conversion of 7-ketocholesterol to oxysterol metabolites by recombinant CYP27A1 and retinal pigment epithelial cells.
Heo GY, Bederman I, Mast N, Liao WL, Turko IV, Pikuleva IA
Journal of lipid research52(6)1117-27(2011 Jun)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
isoLG adduction impairs enzyme activity, and support our hypothesis that isoLG modification in the retina is detrimental to CYP27A1 enzyme activity, potentially disrupting cholesterol homeostasis.
Title: Posttranslational modification by an isolevuglandin diminishes activity of the mitochondrial cytochrome P450 27A1.
Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1.
Title: Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1.
Sterol 27-hydroxylase cytochrome P450 27A1 (CYP27A1) is involved in elimination of 7-ketocholesterol from the retinal pigment epithelium.
Title: Conversion of 7-ketocholesterol to oxysterol metabolites by recombinant CYP27A1 and retinal pigment epithelial cells.
The following CYP27A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP27A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa01571 | |
Clone ID Related Accession (Same CDS sequence) | NM_001083413.2 | |
Accession Version | NM_001083413.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1605bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-13 | |
Organism | Bos taurus(cattle) | |
Product | sterol 26-hydroxylase, mitochondrial | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC123878.1. On Aug 31, 2012 this sequence version replaced NM_001083413.1. ##Evidence-Data-START## Transcript exon combination :: BC123878.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGGGCGCTC TGGGCTCCGC TAGGCTGCGA TGGGCGCTGC TGGGGAGGCG GGCGGCACTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001076882.1 |
CDS | 17..1621 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001083413.2 |
1 | ATGGGCGCTC TGGGCTCCGC TAGGCTGCGA TGGGCGCTGC TGGGGAGGCG GGCGGCACTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Posttranslational modification by an isolevuglandin diminishes activity of the mitochondrial cytochrome P450 27A1. |
Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1. |
Conversion of 7-ketocholesterol to oxysterol metabolites by recombinant CYP27A1 and retinal pigment epithelial cells. |
A whole-genome assembly of the domestic cow, Bos taurus. |