HSP90B1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	HSP90B1
Entrez Gene ID	282646
Full Name	heat shock protein 90 beta family member 1
Synonyms	TRA1
General protein information	Preferred Names heat shock protein 90 beta family member 1 Names endoplasmin 94 kDa glucose-regulated protein GRP-94 GRP94 heat shock protein 90 kDa beta member 1 heat shock protein 90kDa beta (Grp94), member 1 heat shock protein 90kDa beta, member 1 tumor rejection antigen (gp96) 1
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174700.2	NP_777125.1	endoplasmin precursor

Pathways from BioSystems

Homologies

	HSP90B1	XP_001095189.1
Mus musculus (house mouse)	Hsp90b1	NP_035761.1
Rattus norvegicus (Norway rat)	Hsp90b1	NP_001012197.2
Homo sapiens (human)	HSP90B1	NP_003290.1
Canis lupus familiaris (dog)	HSP90B1	NP_001003327.1
Bos taurus (cattle)	HSP90B1	NP_777125.1
Oryza sativa (rice)	Os06g0716700	NP_001058590.1
Gallus gallus (chicken)	HSP90B1	NP_989620.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001424	XP_321706.5
Caenorhabditis elegans (roundworm)	CELE_T05E11.3	NP_001255536.1
Danio rerio (zebrafish)	hsp90b1	NP_937853.1
Drosophila melanogaster (fruit fly)	Gp93	NP_651601.1
Arabidopsis thaliana (thale cress)	SHD	NP_974606.1
Xenopus tropicalis (tropical clawed frog)	hsp90b1	NP_001039228.1
Pan troglodytes (chimpanzee)	HSP90B1	NP_001233416.1

Gene Ontology
Bibliography

Related articles in PubMed

Regulation of endothelial barrier function by TGF-? type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90.
Antonov AS, Antonova GN, Fujii M, ten Dijke P, Handa V, Catravas JD, Verin AD
Journal of cellular physiology227(2)759-71(2012 Feb)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Molecular cloning of bovine (Bos taurus) cDNA encoding a 94-kDa glucose-regulated protein and developmental changes in its mRNA and protein content in the mammary gland.
Watanabe A, Uchida I, Nakata K, Fujimoto Y, Oikawa S
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology130(4)547-57(2001 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study showed that ubiquitinated ALK5 and phosphorylated heat shock protein 27 specifically accumulate in the cytoskeleton fraction, and ALK1 and ALK5 interact with heat shock protein 90(HSP90).
Title: Regulation of endothelial barrier function by TGF-? type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90.

The following HSP90B1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HSP90B1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa42513	NM_174700.2 Latest version!	Bos taurus heat shock protein 90 beta family member 1 (HSP90B1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HSP90B1 ( NM_174700.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_777125.1 Bos taurus heat shock protein 90 beta family member 1 (HSP90B1), mRNA.

Price & Availability↑

CloneID	OBa42513
Clone ID Related Accession (Same CDS sequence)	NM_174700.2
Accession Version	NM_174700.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2415bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Bos taurus(cattle)
Product	endoplasmin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB025193.1. On Jun 3, 2003 this sequence version replaced NM_174700.1. ##Evidence-Data-START## Transcript exon combination :: AB025193.1, BC104549.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END##

ATGAGGGCCC TGTGGGTGCT GGGCCTCTGC TGCGTCCTGC TGACCTTCGG GTCAGTGCGG 
GCTGACGACG AAGTGGATGT GGATGGGACA GTGGAAGAAG ATCTGGGTAA AAGTAGAGAA 
GGCTCAAGGA CAGATGATGA AGTAGTACAG AGAGAGGAAG AAGCTATTCA GTTGGATGGA 
TTAAATGCAT CCCAAATAAG AGAACTTAGA GAGAAATCAG AAAAGTTTGC CTTCCAAGCT 
GAAGTTAACA GAATGATGAA ACTCATCATC AATTCATTGT ATAAAAATAA AGAGATTTTC 
CTGCGAGAAC TGATTTCAAA TGCTTCTGAT GCTTTAGATA AGATAAGACT AATATCACTG 
ACTGATGAAA ATGCTCTTGC TGGAAATGAG GAGTTGACGG TTAAAATTAA GTGTGACAAG 
GAGAAGAACC TGCTGCATGT CACAGACACT GGTGTAGGAA TGACCCGGGA GGAGTTGGTG 
AAAAACCTTG GCACCATAGC CAAGTCTGGA ACAAGCGAGT TTTTAAACAA AATGACTGAG 
GCACAAGAAG ATGGCCAGTC AACATCGGAA CTGATCGGTC AGTTTGGTGT TGGTTTCTAT 
TCTGCCTTCC TTGTGGCAGA TAAAGTTATT GTCACGTCAA AACACAACAA TGACACCCAA 
CACATCTGGG AGTCCGACTC CAATGAATTT TCTGTAATTG CTGACCCCAG AGGAAACACT 
CTCGGACGGG GAACAACCAT TACCCTTGTT TTAAAAGAAG AAGCATCTGA TTACCTTGAA 
TTGGATACAA TTAAAAACCT CGTGAAAAAA TATTCACAGT TCATAAACTT TCCTATTTAT 
GTATGGAGCA GCAAGACCGA AACGGTTGAG GAACCTGCTG AAGAAGAAGA AGCAGCAAAA 
GAAGATAAAG AAGAATCTGA TGATGAAGCT GCAGTAGAAG AAGAGGAAGA CGAAAAGAAA 
CCAAAAACTA AAAAAGTTGA AAAAACTGTC TGGGATTGGG AACTGATGAA CGATATCAAA 
CCCATATGGC AGAGACCATC GAAAGAAGTA GAGGAGGATG AATACAAAGC TTTCTACAAA 
TCATTTTCAA AGGAAAGCGA TGACCCCATG GCATATATCC ACTTTACTGC TGAAGGGGAA 
GTTACCTTCA AGTCAATTTT ATTCGTACCC ACATCTGCCC CACGTGGTCT GTTTGATGAA 
TATGGATCCA AGAAGAGTGA TTACATTAAG CTGTATGTGC GCCGAGTATT CATCACAGAC 
GACTTCCATG ATATGATGCC CAAGTACCTG AATTTTGTCA AGGGTGTTGT GGACTCGGAT 
GATCTCCCCT TGAATGTTTC CCGTGAGACA CTTCAGCAAC ATAAACTGCT TAAGGTGATT 
AGAAAGAAGC TTGTCCGTAA AACTCTGGAC ATGATCAAGA AGATTGCTGA TGAGAAATAC 
AATGATACTT TTTGGAAAGA ATTTGGTACC AACATCAAGC TTGGTGTGAT AGAAGATCAC 
TCAAATCGAA CACGTCTTGC CAAACTTCTT AGATTCCAGT CTTCTCACCA TCCAAGTGAC 
ATGACTAGTC TAGACCAGTA TGTGGAAAGA ATGAAGGAGA AGCAGGACAA AATCTACTTC 
ATGGCTGGGG CCAGCAGGAA AGAGGCCGAA TCTTCTCCCT TTGTTGAGCG ACTTCTGAAA 
AAGGGCTATG AAGTGATTTA TCTCACAGAA CCTGTGGACG AATACTGCAT TCAGGCTCTT 
CCCGAGTTCG ACGGGAAGAG GTTCCAGAAT GTTGCCAAAG AAGGAGTGAA GTTTGATGAA 
AGTGAGAAAA GTAAGGAGAG TCGTGAAGCA GTTGAGAAAG AATTTGAGCC TCTGCTAAAC 
TGGATGAAAG ATAAAGCCCT CAAGGACAAG ATCGAGAAGG CTGTGGTGTC TCAGCGCCTG 
ACAGAGTCTC CGTGTGCTCT GGTAGCCAGC CAGTACGGGT GGTCTGGCAA CATGGAGAGG 
ATCATGAAAG CCCAGGCATA CCAGACAGGC AAGGACATCT CAACCAATTA TTATGCCAGC 
CAGAAGAAAA CATTTGAAAT TAACCCCAGA CACCCACTAA TCAGAGACAT GCTTCGAAGA 
GTTAAGGAAG ATGAAGATGA CAAAACTGTT TCAGATCTTG CTGTGGTTTT GTTTGAAACA 
GCAACACTGC GGTCAGGATA TCTTTTGCCA GACACTAAAG CATATGGAGA CAGAATAGAA 
AGAATGCTTC GCCTCAGCTT AAACATCGAC CCTGATGCAA AGGTTGAAGA AGAACCCGAA 
GAAGAACCTG AGGAAACAAC AGAGGACACT GCAGAAGACA CAGAGCAAGA TGAAGAGGAA 
GAGATGGACG CAGGAACAGA CGAGGAAGAA CAAGAAACAG CAGAGAAATC TACAGCTGAA 
AAAGATGAAC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_777125.1
CDS	98..2512
Translation	MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPAEEEEAAKEDKEESDDEAAVEEEEDEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPSDMTSLDQYVERMKEKQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKSKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRVKEDEDDKTVSDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETTEDTAEDTEQDEEEEMDAGTDEEEQETAEKSTAEKDEL

Target ORF information:

RefSeq Version	NM_174700.2
Organism	Bos taurus(cattle)
Definition	Bos taurus heat shock protein 90 beta family member 1 (HSP90B1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174700.2

ORF Insert Sequence:

ATGAGGGCCC TGTGGGTGCT GGGCCTCTGC TGCGTCCTGC TGACCTTCGG GTCAGTGCGG 
GCTGACGACG AAGTGGATGT GGATGGGACA GTGGAAGAAG ATCTGGGTAA AAGTAGAGAA 
GGCTCAAGGA CAGATGATGA AGTAGTACAG AGAGAGGAAG AAGCTATTCA GTTGGATGGA 
TTAAATGCAT CCCAAATAAG AGAACTTAGA GAGAAATCAG AAAAGTTTGC CTTCCAAGCT 
GAAGTTAACA GAATGATGAA ACTCATCATC AATTCATTGT ATAAAAATAA AGAGATTTTC 
CTGCGAGAAC TGATTTCAAA TGCTTCTGAT GCTTTAGATA AGATAAGACT AATATCACTG 
ACTGATGAAA ATGCTCTTGC TGGAAATGAG GAGTTGACGG TTAAAATTAA GTGTGACAAG 
GAGAAGAACC TGCTGCATGT CACAGACACT GGTGTAGGAA TGACCCGGGA GGAGTTGGTG 
AAAAACCTTG GCACCATAGC CAAGTCTGGA ACAAGCGAGT TTTTAAACAA AATGACTGAG 
GCACAAGAAG ATGGCCAGTC AACATCGGAA CTGATCGGTC AGTTTGGTGT TGGTTTCTAT 
TCTGCCTTCC TTGTGGCAGA TAAAGTTATT GTCACGTCAA AACACAACAA TGACACCCAA 
CACATCTGGG AGTCCGACTC CAATGAATTT TCTGTAATTG CTGACCCCAG AGGAAACACT 
CTCGGACGGG GAACAACCAT TACCCTTGTT TTAAAAGAAG AAGCATCTGA TTACCTTGAA 
TTGGATACAA TTAAAAACCT CGTGAAAAAA TATTCACAGT TCATAAACTT TCCTATTTAT 
GTATGGAGCA GCAAGACCGA AACGGTTGAG GAACCTGCTG AAGAAGAAGA AGCAGCAAAA 
GAAGATAAAG AAGAATCTGA TGATGAAGCT GCAGTAGAAG AAGAGGAAGA CGAAAAGAAA 
CCAAAAACTA AAAAAGTTGA AAAAACTGTC TGGGATTGGG AACTGATGAA CGATATCAAA 
CCCATATGGC AGAGACCATC GAAAGAAGTA GAGGAGGATG AATACAAAGC TTTCTACAAA 
TCATTTTCAA AGGAAAGCGA TGACCCCATG GCATATATCC ACTTTACTGC TGAAGGGGAA 
GTTACCTTCA AGTCAATTTT ATTCGTACCC ACATCTGCCC CACGTGGTCT GTTTGATGAA 
TATGGATCCA AGAAGAGTGA TTACATTAAG CTGTATGTGC GCCGAGTATT CATCACAGAC 
GACTTCCATG ATATGATGCC CAAGTACCTG AATTTTGTCA AGGGTGTTGT GGACTCGGAT 
GATCTCCCCT TGAATGTTTC CCGTGAGACA CTTCAGCAAC ATAAACTGCT TAAGGTGATT 
AGAAAGAAGC TTGTCCGTAA AACTCTGGAC ATGATCAAGA AGATTGCTGA TGAGAAATAC 
AATGATACTT TTTGGAAAGA ATTTGGTACC AACATCAAGC TTGGTGTGAT AGAAGATCAC 
TCAAATCGAA CACGTCTTGC CAAACTTCTT AGATTCCAGT CTTCTCACCA TCCAAGTGAC 
ATGACTAGTC TAGACCAGTA TGTGGAAAGA ATGAAGGAGA AGCAGGACAA AATCTACTTC 
ATGGCTGGGG CCAGCAGGAA AGAGGCCGAA TCTTCTCCCT TTGTTGAGCG ACTTCTGAAA 
AAGGGCTATG AAGTGATTTA TCTCACAGAA CCTGTGGACG AATACTGCAT TCAGGCTCTT 
CCCGAGTTCG ACGGGAAGAG GTTCCAGAAT GTTGCCAAAG AAGGAGTGAA GTTTGATGAA 
AGTGAGAAAA GTAAGGAGAG TCGTGAAGCA GTTGAGAAAG AATTTGAGCC TCTGCTAAAC 
TGGATGAAAG ATAAAGCCCT CAAGGACAAG ATCGAGAAGG CTGTGGTGTC TCAGCGCCTG 
ACAGAGTCTC CGTGTGCTCT GGTAGCCAGC CAGTACGGGT GGTCTGGCAA CATGGAGAGG 
ATCATGAAAG CCCAGGCATA CCAGACAGGC AAGGACATCT CAACCAATTA TTATGCCAGC 
CAGAAGAAAA CATTTGAAAT TAACCCCAGA CACCCACTAA TCAGAGACAT GCTTCGAAGA 
GTTAAGGAAG ATGAAGATGA CAAAACTGTT TCAGATCTTG CTGTGGTTTT GTTTGAAACA 
GCAACACTGC GGTCAGGATA TCTTTTGCCA GACACTAAAG CATATGGAGA CAGAATAGAA 
AGAATGCTTC GCCTCAGCTT AAACATCGAC CCTGATGCAA AGGTTGAAGA AGAACCCGAA 
GAAGAACCTG AGGAAACAAC AGAGGACACT GCAGAAGACA CAGAGCAAGA TGAAGAGGAA 
GAGATGGACG CAGGAACAGA CGAGGAAGAA CAAGAAACAG CAGAGAAATC TACAGCTGAA 
AAAGATGAAC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Regulation of endothelial barrier function by TGF-? type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90.
Journal of cellular physiology227(2)759-71(2012 Feb)
Antonov AS,Antonova GN,Fujii M,ten Dijke P,Handa V,Catravas JD,Verin AD

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Molecular cloning of bovine (Bos taurus) cDNA encoding a 94-kDa glucose-regulated protein and developmental changes in its mRNA and protein content in the mammary gland.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology130(4)547-57(2001 Dec)
Watanabe A,Uchida I,Nakata K,Fujimoto Y,Oikawa S

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HSP90B1 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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