TXNRD2 cDNA ORF clone, Bos taurus(Cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	TXNRD2
Entrez Gene ID	282389
Full Name	thioredoxin reductase 2
General protein information	Preferred Names thioredoxin reductase 2 Names thioredoxin reductase 2, mitochondrial thioredoxin reductase TR3
Gene Type	protein-coding
Organism	Bos taurus(Cattle)
Summary	The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jun 2017].

mRNA and Protein(s)

mRNA	Protein	Name
NM_174626.3	NP_777051.1	thioredoxin reductase 2, mitochondrial precursor
NM_174626.2	NP_777051.1	thioredoxin reductase 2, mitochondrial precursor

Pathways from BioSystems

Homologies

	TXNRD2	NP_001152971.1
Drosophila melanogaster (fruit fly)	Trxr-2	NP_524216.1
Drosophila melanogaster (fruit fly)	Trxr-1	NP_727252.1
Anopheles gambiae (African malaria mosquito)	TRXR	XP_003437030.1
Caenorhabditis elegans (roundworm)	trxr-2	NP_498971.1
Homo sapiens (human)	TXNRD2	NP_006431.2
Mus musculus (house mouse)	Txnrd2	NP_038739.2
Rattus norvegicus (Norway rat)	Txnrd2	NP_072106.1
Pan troglodytes (chimpanzee)	TXNRD2	XP_001166615.2
Xenopus tropicalis (tropical clawed frog)	txnrd2	NP_001120487.1
Canis lupus familiaris (dog)	TXNRD2	XP_005636641.1
Bos taurus (cattle)	TXNRD2	NP_777051.1
Gallus gallus (chicken)	TXNRD2	NP_001116163.1

Gene Ontology
Bibliography

Related articles in PubMed

Selenoprotein Gene Nomenclature.
Gladyshev VN, Arn?r ES, Berry MJ, Brigelius-Floh? R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Floh? L, Green FR, Guig? R, Handy DE, Hatfield DL, Hesketh J, Hoffmann PR, Holmgren A, Hondal RJ, Howard MT, Huang K, Kim HY, Kim IY, K?hrle J, Krol A, Kryukov GV, Lee BJ, Lee BC, Lei XG, Liu Q, Lescure A, Lobanov AV, Loscalzo J, Maiorino M, Mariotti M, Sandeep Prabhu K, Rayman MP, Rozovsky S, Salinas G, Schmidt EE, Schomburg L, Schweizer U, Simonovi? M, Sunde RA, Tsuji PA, Tweedie S, Ursini F, Whanger PD, Zhang Y
The Journal of biological chemistry291(46)24036-24040(2016 Nov)

Composition and evolution of the vertebrate and mammalian selenoproteomes.
Mariotti M, Ridge PG, Zhang Y, Lobanov AV, Pringle TH, Guigo R, Hatfield DL, Gladyshev VN
PloS one7(3)e33066(2012)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Mitochondrial thioredoxin reductase in bovine adrenal cortex its purification, properties, nucleotide/amino acid sequences, and identification of selenocysteine.
Watabe S, Makino Y, Ogawa K, Hiroi T, Yamamoto Y, Takahashi SY
European journal of biochemistry264(1)74-84(1999 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TXNRD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TXNRD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OBa41839	NM_174626.3 Latest version!	Bos taurus thioredoxin reductase 2 (TXNRD2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$342.30 $489.00
View Old Accession Versions >>
OBa41839	NM_174626.2	Bos taurus thioredoxin reductase 2 (TXNRD2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$342.30 $489.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TXNRD2 ( NM_174626.3 ) cDNA ORF clone, Bos taurus(Cattle) -> NP_777051.1 Bos taurus thioredoxin reductase 2 (TXNRD2), mRNA.

Price & Availability↑

CloneID	OBa41839
Clone ID Related Accession (Same CDS sequence)	NM_174626.3 , NM_174626.2
Accession Version	NM_174626.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1536bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Bos taurus(cattle)
Product	thioredoxin reductase 2, mitochondrial precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB022283.1 and EE983361.1. On Jun 27, 2017 this sequence version replaced NM_174626.2. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN03145412, SAMN03145413 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology NMD candidate :: PMID: 10447675 protein contains selenocysteine :: PMID: 10447675 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGC TGCGCGGAGC GGCCGCGCGT TTCCGGGGCC GCGCGCCGGG AGGGGCGCGG 
GGCGCCGCAG GCCGGCAGTG CTACGACCTC CTGGTGATCG GCGGCGGATC CGGCGGCCTG 
GCCTGCGCCA AGGAAGCCGC CCAGCTGGGG AAGAAGGTGG CCGTGCTGGA CTACGTGGAG 
CCTTCCCCCC AAGGCACCAG GTGGGGCCTT GGCGGCACCT GCGTGAACGT CGGCTGCATC 
CCCAAGAAAC TGATGCACCA GGCGGCCCTG CTGGGGGGCA TGATCCGCGA CGCTCCCCAC 
TATGGCTGGG GCGTGGCCCA GGCCCCGCAC AGCTGGGCGA CGCTGGCGGA CGCTGTTCAG 
AACCACGTGA AGTCCCTGAA CTGGGGCCAC CGCATCCAGC TGCAGGACAG GAAAGTCAAG 
TATTTTAACG TCAAGGCCAG CTTTGTCGAC ACGCACACAG TTTGCGGTGT CTCCAAAGGC 
GGGGAGGAGA CTCTGCTTTC GGCCGAGCAC ATTGTCATCG CCACCGGAGG TCGGCCGCGG 
TACCCCACGC ACATCGAAGG TGCCTTGGAA TATGGGATCA CGAGTGATGA CCTCTTCTGG 
CTGAAGGAAT CCCCTGGGAA AACGTTGGTG GTCGGGGCCA GCTACGTAGC CCTGGAGTGC 
GCGGGCCTCC TCACCGGGCT CGGCTTGGAC ACCACCGTCA TGATACGCAG CGTGCCCCTC 
CGGGCCTTCG ACCAGCAAAT GGCTTCGCTG GTCACCGAGC ACATGGCTGG CCACGGCACC 
CGGATCCTAC GGGGCTGCGC CCCCGAGAAG GTAGAGAAAC TCCCAGGCCA GCAGCTCCGC 
GTCACCTGGG TGGACCTCAC CTCGGACCGG AAGGACGCGG GCACCTTTGA CACGGTGCTC 
TGGGCCATAG GCCGAGTTCC AGAAACCGCA AGTCTGAATT TGGAAAAGGC TGGTGTGCAT 
ACGAACCCCG TCACTGGGAA GATCCTCGTT GATGCCCAGG AAACCACCTC CGTCCCCCAC 
ATCTATGCCA TCGGTGATGT GGCAGAGGGG CGGCCGGAGC TGACGCCCAC GGCCATCATG 
GCCGGGCGGC TCCTGGCCCA GCGGCTGAGC GGCCGGACCT CAGACCTGAT GGACTACAGC 
AGCGTCCCCA CGACTGTCTT CACCCCGCTG GAGTACGGCT GCGTGGGGCT GTCAGAGGAG 
GCAGCCGTGG CTCGCCATGG AGAAGAGCAC GTGGAGGTTT ACCACGCGTT CTATAAACCA 
CTGGAGTTCA CTGTCCCCCA GCGGGATGCA TCTCAGTGCT ACATAAAGAT GGTGTGTCTG 
CGGGAGCCCC CACAGCTGGT GCTGGGCCTG CACTTCCTCG GCCCCAACGC AGGCGAAGTT 
ATTCAGGGAT TTGCCCTGGG GATCAAGTGT GGGGCCTCCT ACCAGCAGCT GATGCGGACA 
GTGGGCATCC ACCCCACCTG TGCGGAGGAG GTGGCCAAGC TCCGCATCTC CAAGCGCTCT 
GGCCTGGACC CCACAGTAAC CGGCTGCTGA GGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_777051.1
CDS	16..1551
Translation	MAALRGAAARFRGRAPGGARGAAGRQCYDLLVIGGGSGGLACAKEAAQLGKKVAVLDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAPHYGWGVAQAPHSWATLADAVQNHVKSLNWGHRIQLQDRKVKYFNVKASFVDTHTVCGVSKGGEETLLSAEHIVIATGGRPRYPTHIEGALEYGITSDDLFWLKESPGKTLVVGASYVALECAGLLTGLGLDTTVMIRSVPLRAFDQQMASLVTEHMAGHGTRILRGCAPEKVEKLPGQQLRVTWVDLTSDRKDAGTFDTVLWAIGRVPETASLNLEKAGVHTNPVTGKILVDAQETTSVPHIYAIGDVAEGRPELTPTAIMAGRLLAQRLSGRTSDLMDYSSVPTTVFTPLEYGCVGLSEEAAVARHGEEHVEVYHAFYKPLEFTVPQRDASQCYIKMVCLREPPQLVLGLHFLGPNAGEVIQGFALGIKCGASYQQLMRTVGIHPTCAEEVAKLRISKRSGLDPTVTGC*G

Target ORF information:

RefSeq Version	NM_174626.3
Organism	Bos taurus(cattle)
Definition	Bos taurus thioredoxin reductase 2 (TXNRD2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174626.3

ORF Insert Sequence:

ATGGCGGCGC TGCGCGGAGC GGCCGCGCGT TTCCGGGGCC GCGCGCCGGG AGGGGCGCGG 
GGCGCCGCAG GCCGGCAGTG CTACGACCTC CTGGTGATCG GCGGCGGATC CGGCGGCCTG 
GCCTGCGCCA AGGAAGCCGC CCAGCTGGGG AAGAAGGTGG CCGTGCTGGA CTACGTGGAG 
CCTTCCCCCC AAGGCACCAG GTGGGGCCTT GGCGGCACCT GCGTGAACGT CGGCTGCATC 
CCCAAGAAAC TGATGCACCA GGCGGCCCTG CTGGGGGGCA TGATCCGCGA CGCTCCCCAC 
TATGGCTGGG GCGTGGCCCA GGCCCCGCAC AGCTGGGCGA CGCTGGCGGA CGCTGTTCAG 
AACCACGTGA AGTCCCTGAA CTGGGGCCAC CGCATCCAGC TGCAGGACAG GAAAGTCAAG 
TATTTTAACG TCAAGGCCAG CTTTGTCGAC ACGCACACAG TTTGCGGTGT CTCCAAAGGC 
GGGGAGGAGA CTCTGCTTTC GGCCGAGCAC ATTGTCATCG CCACCGGAGG TCGGCCGCGG 
TACCCCACGC ACATCGAAGG TGCCTTGGAA TATGGGATCA CGAGTGATGA CCTCTTCTGG 
CTGAAGGAAT CCCCTGGGAA AACGTTGGTG GTCGGGGCCA GCTACGTAGC CCTGGAGTGC 
GCGGGCCTCC TCACCGGGCT CGGCTTGGAC ACCACCGTCA TGATACGCAG CGTGCCCCTC 
CGGGCCTTCG ACCAGCAAAT GGCTTCGCTG GTCACCGAGC ACATGGCTGG CCACGGCACC 
CGGATCCTAC GGGGCTGCGC CCCCGAGAAG GTAGAGAAAC TCCCAGGCCA GCAGCTCCGC 
GTCACCTGGG TGGACCTCAC CTCGGACCGG AAGGACGCGG GCACCTTTGA CACGGTGCTC 
TGGGCCATAG GCCGAGTTCC AGAAACCGCA AGTCTGAATT TGGAAAAGGC TGGTGTGCAT 
ACGAACCCCG TCACTGGGAA GATCCTCGTT GATGCCCAGG AAACCACCTC CGTCCCCCAC 
ATCTATGCCA TCGGTGATGT GGCAGAGGGG CGGCCGGAGC TGACGCCCAC GGCCATCATG 
GCCGGGCGGC TCCTGGCCCA GCGGCTGAGC GGCCGGACCT CAGACCTGAT GGACTACAGC 
AGCGTCCCCA CGACTGTCTT CACCCCGCTG GAGTACGGCT GCGTGGGGCT GTCAGAGGAG 
GCAGCCGTGG CTCGCCATGG AGAAGAGCAC GTGGAGGTTT ACCACGCGTT CTATAAACCA 
CTGGAGTTCA CTGTCCCCCA GCGGGATGCA TCTCAGTGCT ACATAAAGAT GGTGTGTCTG 
CGGGAGCCCC CACAGCTGGT GCTGGGCCTG CACTTCCTCG GCCCCAACGC AGGCGAAGTT 
ATTCAGGGAT TTGCCCTGGG GATCAAGTGT GGGGCCTCCT ACCAGCAGCT GATGCGGACA 
GTGGGCATCC ACCCCACCTG TGCGGAGGAG GTGGCCAAGC TCCGCATCTC CAAGCGCTCT 
GGCCTGGACC CCACAGTAAC CGGCTGCTGA GGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TXNRD2 ( NM_174626.2 ) cDNA ORF clone, Bos taurus(Cattle) -> NP_777051.1 Bos taurus thioredoxin reductase 2 (TXNRD2), mRNA.

Price & Availability↑

CloneID	OBa41839
Clone ID Related Accession (Same CDS sequence)	NM_174626.3 , NM_174626.2
Accession Version	NM_174626.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1536bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-21
Organism	Bos taurus(Cattle)
Product	thioredoxin reductase 2, mitochondrial precursor
Comment	VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB022283.1. On Jun 3, 2003 this sequence version replaced NM_174626.1. ##Evidence-Data-START## Transcript exon combination :: AB022283.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00120237, SAMN00120238 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGC TGCGCGGAGC GGCCGCGCGT TTCCGGGGCC GCGCGCCGGG AGGGGCGCGG 
GGCGCCGCAG GCCGGCAGTG CTACGACCTC CTGGTGATCG GCGGCGGATC CGGCGGCCTG 
GCCTGCGCCA AGGAAGCCGC CCAGCTGGGG AAGAAGGTGG CCGTGCTGGA CTACGTGGAG 
CCTTCCCCCC AAGGCACCAG GTGGGGCCTT GGCGGCACCT GCGTGAACGT CGGCTGCATC 
CCCAAGAAAC TGATGCACCA GGCGGCCCTG CTGGGGGGCA TGATCCGCGA CGCTCCCCAC 
TATGGCTGGG GCGTGGCCCA GGCCCCGCAC AGCTGGGCGA CGCTGGCGGA CGCTGTTCAG 
AACCACGTGA AGTCCCTGAA CTGGGGCCAC CGCATCCAGC TGCAGGACAG GAAAGTCAAG 
TATTTTAACG TCAAGGCCAG CTTTGTCGAC ACGCACACAG TTTGCGGTGT CTCCAAAGGC 
GGGGAGGAGA CTCTGCTTTC GGCCGAGCAC ATTGTCATCG CCACCGGAGG TCGGCCGCGG 
TACCCCACGC ACATCGAAGG TGCCTTGGAA TATGGGATCA CGAGTGATGA CCTCTTCTGG 
CTGAAGGAAT CCCCTGGGAA AACGTTGGTG GTCGGGGCCA GCTACGTAGC CCTGGAGTGC 
GCGGGCCTCC TCACCGGGCT CGGCTTGGAC ACCACCGTCA TGATACGCAG CGTGCCCCTC 
CGGGCCTTCG ACCAGCAAAT GGCTTCGCTG GTCACCGAGC ACATGGCTGG CCACGGCACC 
CGGATCCTAC GGGGCTGCGC CCCCGAGAAG GTAGAGAAAC TCCCAGGCCA GCAGCTCCGC 
GTCACCTGGG TGGACCTCAC CTCGGACCGG AAGGACGCGG GCACCTTTGA CACGGTGCTC 
TGGGCCATAG GCCGAGTTCC AGAAACCGCA AGTCTGAATT TGGAAAAGGC TGGTGTGCAT 
ACGAACCCCG TCACTGGGAA GATCCTCGTT GATGCCCAGG AAACCACCTC CGTCCCCCAC 
ATCTATGCCA TCGGTGATGT GGCAGAGGGG CGGCCGGAGC TGACGCCCAC GGCCATCATG 
GCCGGGCGGC TCCTGGCCCA GCGGCTGAGC GGCCGGACCT CAGACCTGAT GGACTACAGC 
AGCGTCCCCA CGACTGTCTT CACCCCGCTG GAGTACGGCT GCGTGGGGCT GTCAGAGGAG 
GCAGCCGTGG CTCGCCATGG AGAAGAGCAC GTGGAGGTTT ACCACGCGTT CTATAAACCA 
CTGGAGTTCA CTGTCCCCCA GCGGGATGCA TCTCAGTGCT ACATAAAGAT GGTGTGTCTG 
CGGGAGCCCC CACAGCTGGT GCTGGGCCTG CACTTCCTCG GCCCCAACGC AGGCGAAGTT 
ATTCAGGGAT TTGCCCTGGG GATCAAGTGT GGGGCCTCCT ACCAGCAGCT GATGCGGACA 
GTGGGCATCC ACCCCACCTG TGCGGAGGAG GTGGCCAAGC TCCGCATCTC CAAGCGCTCT 
GGCCTGGACC CCACAGTAAC CGGCTGCTGA GGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_777051.1
CDS	16..1551
Translation	MAALRGAAARFRGRAPGGARGAAGRQCYDLLVIGGGSGGLACAKEAAQLGKKVAVLDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAPHYGWGVAQAPHSWATLADAVQNHVKSLNWGHRIQLQDRKVKYFNVKASFVDTHTVCGVSKGGEETLLSAEHIVIATGGRPRYPTHIEGALEYGITSDDLFWLKESPGKTLVVGASYVALECAGLLTGLGLDTTVMIRSVPLRAFDQQMASLVTEHMAGHGTRILRGCAPEKVEKLPGQQLRVTWVDLTSDRKDAGTFDTVLWAIGRVPETASLNLEKAGVHTNPVTGKILVDAQETTSVPHIYAIGDVAEGRPELTPTAIMAGRLLAQRLSGRTSDLMDYSSVPTTVFTPLEYGCVGLSEEAAVARHGEEHVEVYHAFYKPLEFTVPQRDASQCYIKMVCLREPPQLVLGLHFLGPNAGEVIQGFALGIKCGASYQQLMRTVGIHPTCAEEVAKLRISKRSGLDPTVTGC*G

Target ORF information:

RefSeq Version	NM_174626.2
Organism	Bos taurus(Cattle)
Definition	Bos taurus thioredoxin reductase 2 (TXNRD2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174626.2

ORF Insert Sequence:

ATGGCGGCGC TGCGCGGAGC GGCCGCGCGT TTCCGGGGCC GCGCGCCGGG AGGGGCGCGG 
GGCGCCGCAG GCCGGCAGTG CTACGACCTC CTGGTGATCG GCGGCGGATC CGGCGGCCTG 
GCCTGCGCCA AGGAAGCCGC CCAGCTGGGG AAGAAGGTGG CCGTGCTGGA CTACGTGGAG 
CCTTCCCCCC AAGGCACCAG GTGGGGCCTT GGCGGCACCT GCGTGAACGT CGGCTGCATC 
CCCAAGAAAC TGATGCACCA GGCGGCCCTG CTGGGGGGCA TGATCCGCGA CGCTCCCCAC 
TATGGCTGGG GCGTGGCCCA GGCCCCGCAC AGCTGGGCGA CGCTGGCGGA CGCTGTTCAG 
AACCACGTGA AGTCCCTGAA CTGGGGCCAC CGCATCCAGC TGCAGGACAG GAAAGTCAAG 
TATTTTAACG TCAAGGCCAG CTTTGTCGAC ACGCACACAG TTTGCGGTGT CTCCAAAGGC 
GGGGAGGAGA CTCTGCTTTC GGCCGAGCAC ATTGTCATCG CCACCGGAGG TCGGCCGCGG 
TACCCCACGC ACATCGAAGG TGCCTTGGAA TATGGGATCA CGAGTGATGA CCTCTTCTGG 
CTGAAGGAAT CCCCTGGGAA AACGTTGGTG GTCGGGGCCA GCTACGTAGC CCTGGAGTGC 
GCGGGCCTCC TCACCGGGCT CGGCTTGGAC ACCACCGTCA TGATACGCAG CGTGCCCCTC 
CGGGCCTTCG ACCAGCAAAT GGCTTCGCTG GTCACCGAGC ACATGGCTGG CCACGGCACC 
CGGATCCTAC GGGGCTGCGC CCCCGAGAAG GTAGAGAAAC TCCCAGGCCA GCAGCTCCGC 
GTCACCTGGG TGGACCTCAC CTCGGACCGG AAGGACGCGG GCACCTTTGA CACGGTGCTC 
TGGGCCATAG GCCGAGTTCC AGAAACCGCA AGTCTGAATT TGGAAAAGGC TGGTGTGCAT 
ACGAACCCCG TCACTGGGAA GATCCTCGTT GATGCCCAGG AAACCACCTC CGTCCCCCAC 
ATCTATGCCA TCGGTGATGT GGCAGAGGGG CGGCCGGAGC TGACGCCCAC GGCCATCATG 
GCCGGGCGGC TCCTGGCCCA GCGGCTGAGC GGCCGGACCT CAGACCTGAT GGACTACAGC 
AGCGTCCCCA CGACTGTCTT CACCCCGCTG GAGTACGGCT GCGTGGGGCT GTCAGAGGAG 
GCAGCCGTGG CTCGCCATGG AGAAGAGCAC GTGGAGGTTT ACCACGCGTT CTATAAACCA 
CTGGAGTTCA CTGTCCCCCA GCGGGATGCA TCTCAGTGCT ACATAAAGAT GGTGTGTCTG 
CGGGAGCCCC CACAGCTGGT GCTGGGCCTG CACTTCCTCG GCCCCAACGC AGGCGAAGTT 
ATTCAGGGAT TTGCCCTGGG GATCAAGTGT GGGGCCTCCT ACCAGCAGCT GATGCGGACA 
GTGGGCATCC ACCCCACCTG TGCGGAGGAG GTGGCCAAGC TCCGCATCTC CAAGCGCTCT 
GGCCTGGACC CCACAGTAAC CGGCTGCTGA GGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Selenoprotein Gene Nomenclature.
The Journal of biological chemistry291(46)24036-24040(2016 Nov)
Gladyshev VN,Arn?r ES,Berry MJ,Brigelius-Floh? R,Bruford EA,Burk RF,Carlson BA,Castellano S,Chavatte L,Conrad M,Copeland PR,Diamond AM,Driscoll DM,Ferreiro A,Floh? L,Green FR,Guig? R,Handy DE,Hatfield DL,Hesketh J,Hoffmann PR,Holmgren A,Hondal RJ,Howard MT,Huang K,Kim HY,Kim IY,K?hrle J,Krol A,Kryukov GV,Lee BJ,Lee BC,Lei XG,Liu Q,Lescure A,Lobanov AV,Loscalzo J,Maiorino M,Mariotti M,Sandeep Prabhu K,Rayman MP,Rozovsky S,Salinas G,Schmidt EE,Schomburg L,Schweizer U,Simonovi? M,Sunde RA,Tsuji PA,Tweedie S,Ursini F,Whanger PD,Zhang Y

Composition and evolution of the vertebrate and mammalian selenoproteomes.
PloS one7(3)e33066(2012)
Mariotti M,Ridge PG,Zhang Y,Lobanov AV,Pringle TH,Guigo R,Hatfield DL,Gladyshev VN

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Mitochondrial thioredoxin reductase in bovine adrenal cortex its purification, properties, nucleotide/amino acid sequences, and identification of selenocysteine.
European journal of biochemistry264(1)74-84(1999 Aug)
Watabe S,Makino Y,Ogawa K,Hiroi T,Yamamoto Y,Takahashi SY

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TXNRD2 cDNA ORF clone, Bos taurus(Cattle)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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