Gene Symbol | LON1 |
Entrez Gene ID | 832744 |
Full Name | lon protease 1 |
Synonyms | F2P16.23,F2P16_23,LON_ARA_ARA,lon protease 1 |
Gene Type | protein-coding |
Organism | Arabidopsis thaliana(thale cress) |
ORF » Species Summary » Arabidopsis thaliana » LON1 cDNA ORF clone
Gene Symbol | LON1 |
Entrez Gene ID | 832744 |
Full Name | lon protease 1 |
Synonyms | F2P16.23,F2P16_23,LON_ARA_ARA,lon protease 1 |
Gene Type | protein-coding |
Organism | Arabidopsis thaliana(thale cress) |
mRNA | Protein | Name |
---|---|---|
NM_122568.4 | NP_568490.4 | lon protease 1 |
Pan troglodytes (chimpanzee) | LONP1 | XP_001143873.1 |
Canis lupus familiaris (dog) | LONP1 | XP_854391.2 |
Mus musculus (house mouse) | Lonp1 | NP_083058.2 |
Rattus norvegicus (Norway rat) | Lonp1 | NP_596895.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010451 | XP_311497.4 |
Caenorhabditis elegans (roundworm) | C34B2.6 | NP_492796.1 |
Homo sapiens (human) | LONP1 | NP_004784.2 |
Bos taurus (cattle) | LONP1 | NP_001015569.2 |
Danio rerio (zebrafish) | lonp1 | XP_691712.4 |
Saccharomyces cerevisiae (baker's yeast) | PIM1 | NP_009531.1 |
Kluyveromyces lactis | KLLA0E10407g | XP_454420.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_11141 | XP_003714792.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100492505 | XP_002938599.1 |
LONP1 | XP_001088663.2 | |
Gallus gallus (chicken) | LONP1 | XP_001232112.2 |
Oryza sativa (rice) | Os07g0689300 | NP_001175344.1 |
Schizosaccharomyces pombe (fission yeast) | lon1 | NP_593035.1 |
Drosophila melanogaster (fruit fly) | Lon | NP_649133.1 |
Neurospora crassa | NCU05261 | XP_961826.1 |
Arabidopsis thaliana (thale cress) | LON1 | NP_568490.3 |
Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.
Tabata S, Kaneko T, Nakamura Y, Kotani H, Kato T, Asamizu E, Miyajima N, Sasamoto S, Kimura T, Hosouchi T, Kawashima K, Kohara M, Matsumoto M, Matsuno A, Muraki A, Nakayama S, Nakazaki N, Naruo K, Okumura S, Shinpo S, Takeuchi C, Wada T, Watanabe A, Yamada M, Yasuda M, Sato S, de la Bastide M, Huang E, Spiegel L, Gnoj L, O'Shaughnessy A, Preston R, Habermann K, Murray J, Johnson D, Rohlfing T, Nelson J, Stoneking T, Pepin K, Spieth J, Sekhon M, Armstrong J, Becker M, Belter E, Cordum H, Cordes M, Courtney L, Courtney W, Dante M, Du H, Edwards J, Fryman J, Haakensen B, Lamar E, Latreille P, Leonard S, Meyer R, Mulvaney E, Ozersky P, Riley A, Strowmatt C, Wagner-McPherson C, Wollam A, Yoakum M, Bell M, Dedhia N, Parnell L, Shah R, Rodriguez M, See LH, Vil D, Baker J, Kirchoff K, Toth K, King L, Bahret A, Miller B, Marra M, Martienssen R, McCombie WR, Wilson RK, Murphy G, Bancroft I, Volckaert G, Wambutt R, D?sterh?ft A, Stiekema W, Pohl T, Entian KD, Terryn N, Hartley N, Bent E, Johnson S, Langham SA, McCullagh B, Robben J, Grymonprez B, Zimmermann W, Ramsperger U, Wedler H, Balke K, Wedler E, Peters S, van Staveren M, Dirkse W, Mooijman P, Lankhorst RK, Weitzenegger T, Bothe G, Rose M, Hauf J, Berneiser S, Hempel S, Feldpausch M, Lamberth S, Villarroel R, Gielen J, Ardiles W, Bents O, Lemcke K, Kolesov G, Mayer K, Rudd S, Schoof H, Schueller C, Zaccaria P, Mewes HW, Bevan M, Fransz P, , ,
Nature408(6814)823-6(2000 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data indicate roles of Lon1 as a chaperone aiding the proper folding of newly synthesized/imported proteins to stabilise them and as a protease to degrade mitochondrial protein aggregates.
Title: Changes in specific protein degradation rates in Arabidopsis thaliana reveal multiple roles of Lon1 in mitochondrial protein homeostasis.
Data postulate that Lon1 and its subfunctional paralog Lon4 evolved complementary subsets of transcriptional and posttranscriptional regulatory components responsive to environmental cues for dual-organellar targeting.
Title: Alternative transcription initiation and the AUG context configuration control dual-organellar targeting and functional competence of Arabidopsis Lon1 protease.
Loss of Lon1 significantly modifies respiratory function and plant performance by small but broad alterations in the mitochondrial proteome.
Title: Loss of Lon1 in Arabidopsis changes the mitochondrial proteome leading to altered metabolite profiles and growth retardation without an accumulation of oxidative damage.
These results shed light on the developmental mechanisms of selective proteolysis in plant mitochondria and suggest a critical role for AtLon1 protease in organelle biogenesis and seedling establishment.
Title: Role of Lon1 protease in post-germinative growth and maintenance of mitochondrial function in Arabidopsis thaliana.
The following LON1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LON1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OAb40376 | |
Clone ID Related Accession (Same CDS sequence) | NM_122568.4 | |
Accession Version | NM_122568.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2958bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-13 | |
Organism | Arabidopsis thaliana(thale cress) | |
Product | lon protease 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003076). On Sep 12, 2016 this sequence version replaced NM_122568.3. |
1 | ATGAAGGGCT TTGATACTAA TCTTCGTCTA CAGGCTTCTT CTCCAGAATT CTCCAATGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_568490.4 |
CDS | 97..3054 |
Translation |
Target ORF information:
Target ORF information:
|
NM_122568.4 |
1 | ATGAAGGGCT TTGATACTAA TCTTCGTCTA CAGGCTTCTT CTCCAGAATT CTCCAATGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. |