Canis lupus familiaris (dog) PI3K/AKT activation (provided by Reactome)

83 gene

The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.

Gene Symbol	Full Name
MTOR	mechanistic target of rapamycin kinase
FGF22	fibroblast growth factor 22
PHLPP2	PH domain and leucine rich repeat protein phosphatase 2
FRS2	fibroblast growth factor receptor substrate 2
CHUK	conserved helix-loop-helix ubiquitous kinase
FGFR2	fibroblast growth factor receptor 2
PIP5K1C	phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
FGFR3	fibroblast growth factor receptor 3
MET	MET proto-oncogene, receptor tyrosine kinase
HGF	hepatocyte growth factor
FGF2	fibroblast growth factor 2
EGFR	epidermal growth factor receptor
PDGFB	platelet derived growth factor subunit B
CREB1	cAMP responsive element binding protein 1
TRIB3	tribbles pseudokinase 3
FGF18	fibroblast growth factor 18
GAB1	GRB2 associated binding protein 1
BTC	betacellulin
RHOA	ras homolog family member A
LCK	LCK proto-oncogene, Src family tyrosine kinase
KLB	klotho beta
PRR5	proline rich 5
GRB2	growth factor receptor bound protein 2
PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
PIP4K2B	phosphatidylinositol-5-phosphate 4-kinase type 2 beta
FGFR4	fibroblast growth factor receptor 4
CDKN1B	cyclin dependent kinase inhibitor 1B
PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
ICOS	inducible T cell costimulator
CD80	CD80 molecule
PIP5K1A	phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
FGF9	fibroblast growth factor 9
TRAT1	T cell receptor associated transmembrane adaptor 1
PDGFRA	platelet derived growth factor receptor alpha
CD28	CD28 molecule
PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PDGFA	platelet derived growth factor subunit A
PDPK1	3-phosphoinositide dependent protein kinase 1
EGF	epidermal growth factor
HBEGF	heparin binding EGF like growth factor
TSC2	TSC complex subunit 2
CASP9	caspase 9
KL	klotho
FOXO4	forkhead box O4
NTRK1	neurotrophic receptor tyrosine kinase 1
AKT1	AKT serine/threonine kinase 1
FGF16	fibroblast growth factor 16
PIK3R2	phosphoinositide-3-kinase regulatory subunit 2
RICTOR	RPTOR independent companion of MTOR complex 2
PDGFRB	platelet derived growth factor receptor beta
FGF4	fibroblast growth factor 4
FGF7	fibroblast growth factor 7
FGF10	fibroblast growth factor 10
PTPN11	protein tyrosine phosphatase, non-receptor type 11
IRS2	insulin receptor substrate 2
NRG2	neuregulin 2
FGF17	fibroblast growth factor 17
ERBB2	erb-b2 receptor tyrosine kinase 2
FGFR1	fibroblast growth factor receptor 1
NRG1	neuregulin 1
FGF19	fibroblast growth factor 19
VAV1	vav guanine nucleotide exchange factor 1
MAPKAP1	mitogen-activated protein kinase associated protein 1
FGF1	fibroblast growth factor 1
MLST8	MTOR associated protein, LST8 homolog
FYN	FYN proto-oncogene, Src family tyrosine kinase
PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1
MDM2	MDM2 proto-oncogene
FGF6	fibroblast growth factor 6
ERBB4	erb-b2 receptor tyrosine kinase 4
CD19	CD19 molecule
AKT1S1	AKT1 substrate 1
RPS6KB2	ribosomal protein S6 kinase B2
KITLG	KIT ligand
FGF5	fibroblast growth factor 5
KIT	KIT proto-oncogene receptor tyrosine kinase
FOXO3	forkhead box O3
PTEN	phosphatase and tensin homolog
CD86	CD86 molecule
CDKN1A	cyclin dependent kinase inhibitor 1A
PIK3R1	phosphoinositide-3-kinase regulatory subunit 1
PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase type 1 beta