KITLG cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	KITLG
Entrez Gene ID	403507
Full Name	KIT ligand
Synonyms	710-712,CSF,MGF
General protein information	Preferred Names KIT ligand Names kit ligand SCF c-kit ligand mast cell growth factor stem cell factor, CSF
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012735.2	NP_001012753.1	kit ligand precursor
XM_014119226.1	XP_013974701.1	kit ligand isoform X1
XM_022427652.1	XP_022283360.1	kit ligand isoform X1

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	kitlg	NP_001039061.1
Pan troglodytes (chimpanzee)	KITLG	XP_509255.2
Mus musculus (house mouse)	Kitl	NP_038626.1
Gallus gallus (chicken)	KITLG	NP_990461.1
Homo sapiens (human)	KITLG	NP_000890.1
Bos taurus (cattle)	KITLG	NP_776800.1
Rattus norvegicus (Norway rat)	Kitlg	NP_068615.1
	KITLG	XP_001101381.2
Canis lupus familiaris (dog)	KITLG	NP_001012753.1

Gene Ontology
Bibliography

Related articles in PubMed

A point mutation in the extracellular domain of KIT promotes tumorigenesis of mast cells via ligand-independent auto-dimerization.
Amagai Y, Matsuda A, Jung K, Oida K, Jang H, Ishizaka S, Matsuda H, Tanaka A
Scientific reports59775(2015 May)

The value of molecular expression of KIT and KIT ligand analysed using real-time polymerase chain reaction and immunohistochemistry as a prognostic indicator for canine cutaneous mast cell tumours.
Costa Casagrande TA, de Oliveira Barros LM, Fukumasu H, Cogliati B, Chaible LM, Dagli ML, Matera JM
Veterinary and comparative oncology13(1)1-10(2015 Mar)

A copy number variant at the KITLG locus likely confers risk for canine squamous cell carcinoma of the digit.
Karyadi DM, Karlins E, Decker B, vonHoldt BM, Carpintero-Ramirez G, Parker HG, Wayne RK, Ostrander EA
PLoS genetics9(3)e1003409(2013 Mar)

Canine stem cell factor augments expression of matrix metalloproteinase-9 by CD34 cells.
Ostronoff LK, Kremmer E, Ferm?n ML, Frag?o C, Mysliwietz J, Kolb HJ, Tejero C
Cytotherapy10(2)193-202(2008)

Evaluation of dysregulation of the receptor tyrosine kinases Kit, Flt3, and Met in histiocytic sarcomas of dogs.
Zavodovskaya R, Liao AT, Jones CL, Yip B, Chien MB, Moore PF, London CA
American journal of veterinary research67(4)633-41(2006 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A point mutation in the extracellular domain of KIT promotes tumorigenesis of mast cells via ligand-independent auto-dimerization
Title: A point mutation in the extracellular domain of KIT promotes tumorigenesis of mast cells via ligand-independent auto-dimerization.

The relationship between KIT gene expression and tumor recurrence and mortality in dogs with cutaneous mast cell tumors was investigated via RT-PCR and immunohistochemistry.
Title: The value of molecular expression of KIT and KIT ligand analysed using real-time polymerase chain reaction and immunohistochemistry as a prognostic indicator for canine cutaneous mast cell tumours.

Our findings highlight a role for KITLG in SCCD susceptibility, as well as demonstrate that interactions between the KITLG and MC1R loci are potentially required for SCCD oncogenesis
Title: A copy number variant at the KITLG locus likely confers risk for canine squamous cell carcinoma of the digit.

The aim of this work was to evaluate whether canine stem cell factor (cSCF) contributes to matrix metalloproteinase (MMP)-9 secretion by CD34 cells.
Title: Canine stem cell factor augments expression of matrix metalloproteinase-9 by CD34 cells.

Dysregulation of Kit/SCF, Flt3/Flt3L, and Met/HGF signaling pathways is unlikely to occur in histiocytic sarcomas of dogs.
Title: Evaluation of dysregulation of the receptor tyrosine kinases Kit, Flt3, and Met in histiocytic sarcomas of dogs.

The following KITLG gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KITLG cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCe00479	NM_001012735.2 Latest version!	Canis lupus familiaris KIT ligand (KITLG), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OCe40066	XM_014119226.1 Latest version!	Canis lupus familiaris KIT ligand (KITLG), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00
OCe40066	XM_022427652.1 Latest version!	Canis lupus familiaris KIT ligand (KITLG), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KITLG ( NM_001012735.2 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001012753.1 Canis lupus familiaris KIT ligand (KITLG), mRNA.

Price & Availability↑

CloneID	OCe00479
Clone ID Related Accession (Same CDS sequence)	NM_001012735.2
Accession Version	NM_001012735.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Canis lupus familiaris(dog)
Product	kit ligand precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAEX03009912.1. On Sep 1, 2015 this sequence version replaced NM_001012735.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the same breed was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END##

ATGAAGAAGA CACAAACTTG GATTATCACT TGCATTTATC TTCAGCTGCT CCTATTTAAT 
CCTCTGGTCA AAACTAAAGG GATCTGCGGG AAACGTGTGA CTGATGATGT GAAGGACGTT 
ACAAAATTGG TGGCAAATCT TCCAAAAGAC TATAAGATAG CCCTCAAATA TGTCCCCGGG 
ATGGATGTTT TGCCTAGTCA TTGTTGGATA AGCGTGATGG TGGAACAGTT GTCAGTCAGC 
TTGACTGATC TTCTGGACAA GTTTTCAAAT ATTTCTGAAG GCCTGAGTAA TTATTCTATC 
ATAGACAAAC TTGTGAAAAT AGTGGATGAT CTTGTGGAGT GCACAGAAGG ATACTCATTT 
GAGAATGTAA AAAAAGCACC TAAGAGCCCA GAACTCAGGC TTTTTACTCC TGAAGAATTC 
TTTAGAATTT TTAATAGATC CATCGATGCC TTTAAGGACT TGGAGACGGT GGCATCTAAA 
AGTAGTGAAT GTGTGGTTTC TTCAACCTTA AGTCCTGATA AAGATTCCAG AGTCAGTGTC 
ACAAAACCAT TTATGTTACC CCCTGTTGCA GCCAGCTCCC TTAGGAATGA CAGCAGTAGC 
AGTAATAGGA AGGCCTCAAA TTCCATTGGA GACTCCAACT TACAATGGGC AGCCATGGCA 
TTGCCAGCAT TCTTTTCTCT TGTAATTGGG TTTGCTTTTG GAGCCTTATA CTGGAAGAAG 
AAACAACCAA ATCTCACAAG GACAGTTGAA AATATACAGA TTAATGAAGA GGATAATGAA 
ATAAGTATGT TGCAAGAGAA AGAGAGGGAG TTTCAAGAGG TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012753.1
CDS	195..1019
Translation	MKKTQTWIITCIYLQLLLFNPLVKTKGICGKRVTDDVKDVTKLVANLPKDYKIALKYVPGMDVLPSHCWISVMVEQLSVSLTDLLDKFSNISEGLSNYSIIDKLVKIVDDLVECTEGYSFENVKKAPKSPELRLFTPEEFFRIFNRSIDAFKDLETVASKSSECVVSSTLSPDKDSRVSVTKPFMLPPVAASSLRNDSSSSNRKASNSIGDSNLQWAAMALPAFFSLVIGFAFGALYWKKKQPNLTRTVENIQINEEDNEISMLQEKEREFQEV

Target ORF information:

RefSeq Version	NM_001012735.2
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris KIT ligand (KITLG), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012735.2

ORF Insert Sequence:

ATGAAGAAGA CACAAACTTG GATTATCACT TGCATTTATC TTCAGCTGCT CCTATTTAAT 
CCTCTGGTCA AAACTAAAGG GATCTGCGGG AAACGTGTGA CTGATGATGT GAAGGACGTT 
ACAAAATTGG TGGCAAATCT TCCAAAAGAC TATAAGATAG CCCTCAAATA TGTCCCCGGG 
ATGGATGTTT TGCCTAGTCA TTGTTGGATA AGCGTGATGG TGGAACAGTT GTCAGTCAGC 
TTGACTGATC TTCTGGACAA GTTTTCAAAT ATTTCTGAAG GCCTGAGTAA TTATTCTATC 
ATAGACAAAC TTGTGAAAAT AGTGGATGAT CTTGTGGAGT GCACAGAAGG ATACTCATTT 
GAGAATGTAA AAAAAGCACC TAAGAGCCCA GAACTCAGGC TTTTTACTCC TGAAGAATTC 
TTTAGAATTT TTAATAGATC CATCGATGCC TTTAAGGACT TGGAGACGGT GGCATCTAAA 
AGTAGTGAAT GTGTGGTTTC TTCAACCTTA AGTCCTGATA AAGATTCCAG AGTCAGTGTC 
ACAAAACCAT TTATGTTACC CCCTGTTGCA GCCAGCTCCC TTAGGAATGA CAGCAGTAGC 
AGTAATAGGA AGGCCTCAAA TTCCATTGGA GACTCCAACT TACAATGGGC AGCCATGGCA 
TTGCCAGCAT TCTTTTCTCT TGTAATTGGG TTTGCTTTTG GAGCCTTATA CTGGAAGAAG 
AAACAACCAA ATCTCACAAG GACAGTTGAA AATATACAGA TTAATGAAGA GGATAATGAA 
ATAAGTATGT TGCAAGAGAA AGAGAGGGAG TTTCAAGAGG TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KITLG ( XM_014119226.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_013974701.1 Canis lupus familiaris KIT ligand (KITLG), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe40066
Clone ID Related Accession (Same CDS sequence)	XM_014119226.1 , XM_022427652.1
Accession Version	XM_014119226.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	kit ligand isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726085.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAAGA CACAAACTTG GATTATCACT TGCATTTATC TTCAGCTGCT CCTATTTAAT 
CCTCTGGTCA AAACTAAAGG GATCTGCGGG AAACGTGTGA CTGATGATGT GAAGGACGTT 
ACAAAATTGG TGGCAAATCT TCCAAAAGAC TATAAGATAG CCCTCAAATA TGTCCCCGGG 
ATGGATGTTT TGCCTAGTCA TTGTTGGATA AGCGTGATGG TGGAACAGTT GTCAGTCAGC 
TTGACTGATC TTCTGGACAA GTTTTCAAAT ATTTCTGAAG GCCTGAGTAA TTATTCTATC 
ATAGACAAAC TTGTGAAAAT AGTGGATGAT CTTGTGGAGT GCACAGAAGG ATACTCATTT 
GAGAATGTAA AAAAAGCACC TAAGAGCCCA GAACTCAGGC TTTTTACTCC TGAAGAATTC 
TTTAGAATTT TTAATAGATC CATCGATGCC TTTAAGGACT TGGAGACGGT GGCATCTAAA 
AGTAGTGAAT GTGTGGTTTC TTCAACCTTA AGTCCTGATA AAGGGAAGGC CTCAAATTCC 
ATTGGAGACT CCAACTTACA ATGGGCAGCC ATGGCATTGC CAGCATTCTT TTCTCTTGTA 
ATTGGGTTTG CTTTTGGAGC CTTATACTGG AAGAAGAAAC AACCAAATCT CACAAGGACA 
GTTGAAAATA TACAGATTAA TGAAGAGGAT AATGAAATAA GTATGTTGCA AGAGAAAGAG 
AGGGAGTTTC AAGAGGTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_013974701.1
CDS	213..953
Translation	MKKTQTWIITCIYLQLLLFNPLVKTKGICGKRVTDDVKDVTKLVANLPKDYKIALKYVPGMDVLPSHCWISVMVEQLSVSLTDLLDKFSNISEGLSNYSIIDKLVKIVDDLVECTEGYSFENVKKAPKSPELRLFTPEEFFRIFNRSIDAFKDLETVASKSSECVVSSTLSPDKGKASNSIGDSNLQWAAMALPAFFSLVIGFAFGALYWKKKQPNLTRTVENIQINEEDNEISMLQEKEREFQEV

Target ORF information:

RefSeq Version	XM_014119226.1
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris KIT ligand (KITLG), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_014119226.1

ORF Insert Sequence:

ATGAAGAAGA CACAAACTTG GATTATCACT TGCATTTATC TTCAGCTGCT CCTATTTAAT 
CCTCTGGTCA AAACTAAAGG GATCTGCGGG AAACGTGTGA CTGATGATGT GAAGGACGTT 
ACAAAATTGG TGGCAAATCT TCCAAAAGAC TATAAGATAG CCCTCAAATA TGTCCCCGGG 
ATGGATGTTT TGCCTAGTCA TTGTTGGATA AGCGTGATGG TGGAACAGTT GTCAGTCAGC 
TTGACTGATC TTCTGGACAA GTTTTCAAAT ATTTCTGAAG GCCTGAGTAA TTATTCTATC 
ATAGACAAAC TTGTGAAAAT AGTGGATGAT CTTGTGGAGT GCACAGAAGG ATACTCATTT 
GAGAATGTAA AAAAAGCACC TAAGAGCCCA GAACTCAGGC TTTTTACTCC TGAAGAATTC 
TTTAGAATTT TTAATAGATC CATCGATGCC TTTAAGGACT TGGAGACGGT GGCATCTAAA 
AGTAGTGAAT GTGTGGTTTC TTCAACCTTA AGTCCTGATA AAGGGAAGGC CTCAAATTCC 
ATTGGAGACT CCAACTTACA ATGGGCAGCC ATGGCATTGC CAGCATTCTT TTCTCTTGTA 
ATTGGGTTTG CTTTTGGAGC CTTATACTGG AAGAAGAAAC AACCAAATCT CACAAGGACA 
GTTGAAAATA TACAGATTAA TGAAGAGGAT AATGAAATAA GTATGTTGCA AGAGAAAGAG 
AGGGAGTTTC AAGAGGTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KITLG ( XM_022427652.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_022283360.1 Canis lupus familiaris KIT ligand (KITLG), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe40066
Clone ID Related Accession (Same CDS sequence)	XM_014119226.1 , XM_022427652.1
Accession Version	XM_022427652.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	kit ligand isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006597.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGAAGA CACAAACTTG GATTATCACT TGCATTTATC TTCAGCTGCT CCTATTTAAT 
CCTCTGGTCA AAACTAAAGG GATCTGCGGG AAACGTGTGA CTGATGATGT GAAGGACGTT 
ACAAAATTGG TGGCAAATCT TCCAAAAGAC TATAAGATAG CCCTCAAATA TGTCCCCGGG 
ATGGATGTTT TGCCTAGTCA TTGTTGGATA AGCGTGATGG TGGAACAGTT GTCAGTCAGC 
TTGACTGATC TTCTGGACAA GTTTTCAAAT ATTTCTGAAG GCCTGAGTAA TTATTCTATC 
ATAGACAAAC TTGTGAAAAT AGTGGATGAT CTTGTGGAGT GCACAGAAGG ATACTCATTT 
GAGAATGTAA AAAAAGCACC TAAGAGCCCA GAACTCAGGC TTTTTACTCC TGAAGAATTC 
TTTAGAATTT TTAATAGATC CATCGATGCC TTTAAGGACT TGGAGACGGT GGCATCTAAA 
AGTAGTGAAT GTGTGGTTTC TTCAACCTTA AGTCCTGATA AAGGGAAGGC CTCAAATTCC 
ATTGGAGACT CCAACTTACA ATGGGCAGCC ATGGCATTGC CAGCATTCTT TTCTCTTGTA 
ATTGGGTTTG CTTTTGGAGC CTTATACTGG AAGAAGAAAC AACCAAATCT CACAAGGACA 
GTTGAAAATA TACAGATTAA TGAAGAGGAT AATGAAATAA GTATGTTGCA AGAGAAAGAG 
AGGGAGTTTC AAGAGGTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_022283360.1
CDS	206..946
Translation	MKKTQTWIITCIYLQLLLFNPLVKTKGICGKRVTDDVKDVTKLVANLPKDYKIALKYVPGMDVLPSHCWISVMVEQLSVSLTDLLDKFSNISEGLSNYSIIDKLVKIVDDLVECTEGYSFENVKKAPKSPELRLFTPEEFFRIFNRSIDAFKDLETVASKSSECVVSSTLSPDKGKASNSIGDSNLQWAAMALPAFFSLVIGFAFGALYWKKKQPNLTRTVENIQINEEDNEISMLQEKEREFQEV

Target ORF information:

RefSeq Version	XM_022427652.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris KIT ligand (KITLG), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_022427652.1

ORF Insert Sequence:

ATGAAGAAGA CACAAACTTG GATTATCACT TGCATTTATC TTCAGCTGCT CCTATTTAAT 
CCTCTGGTCA AAACTAAAGG GATCTGCGGG AAACGTGTGA CTGATGATGT GAAGGACGTT 
ACAAAATTGG TGGCAAATCT TCCAAAAGAC TATAAGATAG CCCTCAAATA TGTCCCCGGG 
ATGGATGTTT TGCCTAGTCA TTGTTGGATA AGCGTGATGG TGGAACAGTT GTCAGTCAGC 
TTGACTGATC TTCTGGACAA GTTTTCAAAT ATTTCTGAAG GCCTGAGTAA TTATTCTATC 
ATAGACAAAC TTGTGAAAAT AGTGGATGAT CTTGTGGAGT GCACAGAAGG ATACTCATTT 
GAGAATGTAA AAAAAGCACC TAAGAGCCCA GAACTCAGGC TTTTTACTCC TGAAGAATTC 
TTTAGAATTT TTAATAGATC CATCGATGCC TTTAAGGACT TGGAGACGGT GGCATCTAAA 
AGTAGTGAAT GTGTGGTTTC TTCAACCTTA AGTCCTGATA AAGGGAAGGC CTCAAATTCC 
ATTGGAGACT CCAACTTACA ATGGGCAGCC ATGGCATTGC CAGCATTCTT TTCTCTTGTA 
ATTGGGTTTG CTTTTGGAGC CTTATACTGG AAGAAGAAAC AACCAAATCT CACAAGGACA 
GTTGAAAATA TACAGATTAA TGAAGAGGAT AATGAAATAA GTATGTTGCA AGAGAAAGAG 
AGGGAGTTTC AAGAGGTGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A point mutation in the extracellular domain of KIT promotes tumorigenesis of mast cells via ligand-independent auto-dimerization.
Scientific reports59775(2015 May)
Amagai Y,Matsuda A,Jung K,Oida K,Jang H,Ishizaka S,Matsuda H,Tanaka A

The value of molecular expression of KIT and KIT ligand analysed using real-time polymerase chain reaction and immunohistochemistry as a prognostic indicator for canine cutaneous mast cell tumours.
Veterinary and comparative oncology13(1)1-10(2015 Mar)
Costa Casagrande TA,de Oliveira Barros LM,Fukumasu H,Cogliati B,Chaible LM,Dagli ML,Matera JM

A copy number variant at the KITLG locus likely confers risk for canine squamous cell carcinoma of the digit.
PLoS genetics9(3)e1003409(2013 Mar)
Karyadi DM,Karlins E,Decker B,vonHoldt BM,Carpintero-Ramirez G,Parker HG,Wayne RK,Ostrander EA

Canine stem cell factor augments expression of matrix metalloproteinase-9 by CD34 cells.
Cytotherapy10(2)193-202(2008)
Ostronoff LK,Kremmer E,Ferm?n ML,Frag?o C,Mysliwietz J,Kolb HJ,Tejero C

Evaluation of dysregulation of the receptor tyrosine kinases Kit, Flt3, and Met in histiocytic sarcomas of dogs.
American journal of veterinary research67(4)633-41(2006 Apr)
Zavodovskaya R,Liao AT,Jones CL,Yip B,Chien MB,Moore PF,London CA

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KITLG cDNA ORF clone, Canis lupus familiaris(dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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