Gene Symbol | nca-2 |
Entrez Gene ID | 175674 |
Full Name | Novel Channel type/putative Nematode CAlcium channel |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » nca-2 cDNA ORF clone
Gene Symbol | nca-2 |
Entrez Gene ID | 175674 |
Full Name | Novel Channel type/putative Nematode CAlcium channel |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001136363.2 | NP_001129835.1 | Novel Channel type/putative Nematode CAlcium channel |
NM_065653.4 | NP_498054.2 | Novel Channel type/putative Nematode CAlcium channel |
NM_001136363.3 | NP_001129835.1 | Novel Channel type/putative Nematode CAlcium channel |
NM_065653.5 | NP_498054.2 | Novel Channel type/putative Nematode CAlcium channel |
Pan troglodytes (chimpanzee) | NALCN | XP_001149573.1 |
Canis lupus familiaris (dog) | NALCN | XP_542654.4 |
Bos taurus (cattle) | NALCN | XP_002692026.1 |
Rattus norvegicus (Norway rat) | Nalcn | NP_705894.1 |
Drosophila melanogaster (fruit fly) | na | NP_001096981.1 |
Homo sapiens (human) | NALCN | NP_443099.1 |
Caenorhabditis elegans (roundworm) | nca-2 | NP_498054.2 |
Mus musculus (house mouse) | Nalcn | NP_796367.3 |
Caenorhabditis elegans (roundworm) | unc-77 | NP_741413.2 |
Gallus gallus (chicken) | NALCN | XP_416967.2 |
Danio rerio (zebrafish) | nalcn | NP_001017549.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003921 | XP_318373.5 |
Xenopus tropicalis (tropical clawed frog) | nalcn | XP_002937125.2 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Genetic epistasis experiments suggest that GRK-2 acts on the D2-like dopamine receptor DOP-3 to inhibit Go signaling and positively modulate NCA-1 and NCA-2 activity.
Title: Dopamine negatively modulates the NCA ion channels in C. elegans.
Our results suggest that NCA-1 and NCA-2 are physiologically relevant targets of neuronal Gq-Rho signaling in C. elegans
Title: The NCA-1 and NCA-2 Ion Channels Function Downstream of G
UNC-80 is required for the proper localization of the NCA-1 and NCA-2 ion channel subunits.
Title: UNC-80 and the NCA ion channels contribute to endocytosis defects in synaptojanin mutants.
The following nca-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the nca-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa341127 | |
Clone ID Related Accession (Same CDS sequence) | NM_065653.4 , NM_065653.5 | |
Accession Version | NM_065653.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5358bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Novel Channel type/putative Nematode CAlcium channel | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_065653.3. COMPLETENESS: incomplete on both ends. |
1 | ATGACTTCAA CAACTGCAAA ATTGTTGGGA CTGTCAGCGT GCCGTGCGGC CGCATTGTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_498054.2 |
CDS | 1..5358 |
Translation |
Target ORF information:
Target ORF information:
|
NM_065653.4 |
1 | ATGACTTCAA CAACTGCAAA ATTGTTGGGA CTGTCAGCGT GCCGTGCGGC CGCATTGTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341127 | |
Clone ID Related Accession (Same CDS sequence) | NM_065653.4 , NM_065653.5 | |
Accession Version | NM_065653.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5358bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Novel Channel type/putative Nematode CAlcium channel | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_065653.4. |
1 | ATGACTTCAA CAACTGCAAA ATTGTTGGGA CTGTCAGCGT GCCGTGCGGC CGCATTGTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_498054.2 |
CDS | 91..5448 |
Translation |
Target ORF information:
Target ORF information:
|
NM_065653.5 |
1 | ATGACTTCAA CAACTGCAAA ATTGTTGGGA CTGTCAGCGT GCCGTGCGGC CGCATTGTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341131 | |
Clone ID Related Accession (Same CDS sequence) | NM_001136363.2 , NM_001136363.3 | |
Accession Version | NM_001136363.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5292bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Novel Channel type/putative Nematode CAlcium channel | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_001136363.1. COMPLETENESS: incomplete on both ends. |
1 | ATGCTGACGC GCCGCAAATC GTCAATAGAT GGAACAAAAA CAGAAAGAAA TCGGAGAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001129835.1 |
CDS | 1..5292 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001136363.2 |
1 | ATGCTGACGC GCCGCAAATC GTCAATAGAT GGAACAAAAA CAGAAAGAAA TCGGAGAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341131 | |
Clone ID Related Accession (Same CDS sequence) | NM_001136363.2 , NM_001136363.3 | |
Accession Version | NM_001136363.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5292bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Novel Channel type/putative Nematode CAlcium channel | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001136363.2. |
1 | ATGCTGACGC GCCGCAAATC GTCAATAGAT GGAACAAAAA CAGAAAGAAA TCGGAGAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001129835.1 |
CDS | 39..5330 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001136363.3 |
1 | ATGCTGACGC GCCGCAAATC GTCAATAGAT GGAACAAAAA CAGAAAGAAA TCGGAGAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |